Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7pip_9.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A N GLU 264.A OE2 no hydrogen 2.958 N/A LYS 4.A NZ PHE 5.A O no hydrogen 2.829 N/A LYS 4.A NZ ASP 266.A OD1 no hydrogen 2.149 N/A PHE 5.A N GLU 264.A O no hydrogen 3.123 N/A ARG 7.A N ASP 266.A OD2 no hydrogen 2.493 N/A ARG 7.A NH2 HIS 75.A ND1 no hydrogen 3.562 N/A SER 8.A OG ASP 6.A O no hydrogen 3.506 N/A LYS 9.A NZ ASP 72.A O no hydrogen 2.492 N/A VAL 12.A N HIS 75.A O no hydrogen 2.926 N/A VAL 14.A N ALA 77.A O no hydrogen 2.745 N/A ILE 17.A N ILE 102.A O no hydrogen 3.300 N/A THR 25.A OG1 TYR 46.A O no hydrogen 2.855 N/A THR 26.A OG1 GLY 23.A O no hydrogen 2.300 N/A LEU 27.A N GLY 23.A O no hydrogen 2.581 N/A THR 28.A N LYS 24.A O no hydrogen 2.913 N/A THR 28.A OG1 LYS 24.A O no hydrogen 3.208 N/A THR 28.A OG1 THR 25.A O no hydrogen 2.482 N/A ALA 29.A N THR 25.A O no hydrogen 2.952 N/A ALA 30.A N THR 26.A O no hydrogen 2.816 N/A ILE 31.A N LEU 27.A O no hydrogen 2.922 N/A CYS 32.A SG THR 28.A O no hydrogen 3.423 N/A CYS 32.A SG ALA 43.A O no hydrogen 3.368 N/A THR 33.A N ALA 29.A O no hydrogen 2.935 N/A THR 33.A OG1 ALA 29.A O no hydrogen 2.942 N/A THR 33.A OG1 ALA 30.A O no hydrogen 2.861 N/A VAL 34.A N ALA 30.A O no hydrogen 2.869 N/A LEU 35.A N ILE 31.A O no hydrogen 2.950 N/A LYS 37.A N VAL 34.A O no hydrogen 3.376 N/A LYS 37.A NZ LYS 37.A O no hydrogen 3.200 N/A LYS 40.A N ASP 72.A OD1 no hydrogen 2.862 N/A LYS 40.A NZ LYS 37.A O no hydrogen 2.704 N/A THR 44.A OG1 ALA 42.A O no hydrogen 3.317 N/A TYR 46.A N GLN 48.A OE1 no hydrogen 3.305 N/A LYS 51.A N GLU 55.A OE1 no hydrogen 2.533 N/A ALA 52.A N GLU 55.A OE1 no hydrogen 2.876 N/A GLU 55.A N ALA 52.A O no hydrogen 2.936 N/A LYS 56.A N ALA 52.A O no hydrogen 2.644 N/A LYS 56.A NZ ASP 47.A O no hydrogen 2.979 N/A LYS 56.A NZ ASP 50.A O no hydrogen 2.511 N/A SER 64.A OG ASP 80.A O no hydrogen 2.815 N/A HIS 66.A NE2 GLN 97.A OE1 no hydrogen 2.623 N/A VAL 67.A N HIS 78.A O no hydrogen 2.918 N/A TYR 69.A N TYR 76.A O no hydrogen 2.949 N/A SER 70.A N SER 41.A O no hydrogen 3.182 N/A SER 70.A OG SER 71.A O no hydrogen 3.214 N/A SER 70.A OG ARG 74.A O no hydrogen 3.331 N/A SER 71.A N ARG 74.A O no hydrogen 2.587 N/A SER 71.A OG ARG 74.A O no hydrogen 3.039 N/A LYS 73.A N SER 71.A OG no hydrogen 2.914 N/A ARG 74.A N SER 71.A OG no hydrogen 2.823 N/A ARG 74.A NH2 HIS 11.A O no hydrogen 2.850 N/A ARG 74.A NH2 THR 201.A OG1 no hydrogen 2.345 N/A HIS 75.A N PRO 10.A O no hydrogen 2.430 N/A TYR 76.A N TYR 69.A O no hydrogen 2.889 N/A ALA 77.A N VAL 12.A O no hydrogen 3.360 N/A HIS 78.A N VAL 67.A O no hydrogen 2.882 N/A VAL 79.A N VAL 14.A O no hydrogen 2.893 N/A ASP 80.A N ALA 65.A O no hydrogen 2.928 N/A CYS 81.A N VAL 79.A O no hydrogen 2.956 N/A CYS 81.A SG THR 16.A O no hydrogen 3.391 N/A CYS 81.A SG VAL 79.A O no hydrogen 3.483 N/A TYR 87.A N HIS 84.A O no hydrogen 2.931 N/A MET 91.A N TYR 87.A O no hydrogen 3.408 N/A ILE 92.A N ILE 88.A O no hydrogen 2.902 N/A THR 93.A N LYS 89.A O no hydrogen 3.007 N/A THR 93.A OG1 LYS 89.A O no hydrogen 3.567 N/A THR 93.A OG1 ASN 90.A O no hydrogen 2.845 N/A ALA 95.A N MET 91.A O no hydrogen 2.795 N/A ALA 96.A N ILE 92.A O no hydrogen 2.483 N/A GLN 97.A N GLY 94.A O no hydrogen 2.930 N/A GLY 100.A N ASN 13.A O no hydrogen 2.908 N/A ILE 102.A N GLY 15.A O no hydrogen 2.874 N/A LEU 103.A N VAL 131.A O no hydrogen 3.075 N/A VAL 104.A N ILE 17.A O no hydrogen 2.645 N/A SER 106.A OG HIS 22.A O no hydrogen 3.264 N/A ALA 107.A N ASN 135.A O no hydrogen 2.717 N/A THR 108.A OG1 ASP 109.A OD1 no hydrogen 3.318 N/A SER 110.A OG SER 106.A O no hydrogen 2.921 N/A ARG 116.A N MET 112.A O no hydrogen 2.923 N/A GLU 117.A N PRO 113.A O no hydrogen 2.916 N/A HIS 118.A N GLN 114.A O no hydrogen 2.894 N/A HIS 118.A ND1 GLN 114.A O no hydrogen 2.244 N/A HIS 118.A NE2 PRO 82.A O no hydrogen 2.846 N/A ILE 119.A N THR 115.A O no hydrogen 2.908 N/A LEU 120.A N ARG 116.A O no hydrogen 2.920 N/A LEU 121.A N GLU 117.A O no hydrogen 2.912 N/A ALA 122.A N HIS 118.A O no hydrogen 2.905 N/A ARG 123.A N ILE 119.A O no hydrogen 2.911 N/A ARG 123.A NE ARG 123.A O no hydrogen 2.550 N/A GLN 124.A N LEU 120.A O no hydrogen 2.891 N/A GLN 124.A NE2 PHE 374.A O no hydrogen 2.393 N/A VAL 125.A N LEU 121.A O no hydrogen 2.926 N/A GLY 126.A N ALA 122.A O no hydrogen 3.354 N/A VAL 132.A N PRO 168.A O no hydrogen 3.030 N/A PHE 133.A N LEU 103.A O no hydrogen 3.238 N/A LEU 134.A N ILE 170.A O no hydrogen 2.470 N/A ASN 135.A N VAL 105.A O no hydrogen 3.037 N/A CYS 137.A N GLY 172.A O no hydrogen 3.096 N/A CYS 137.A SG LEU 134.A O no hydrogen 4.025 N/A CYS 137.A SG GLY 172.A O no hydrogen 3.221 N/A THR 141.A OG1 CYS 137.A O no hydrogen 2.441 N/A THR 141.A OG1 ASP 138.A O no hydrogen 3.025 N/A LEU 148.A N GLU 144.A O no hydrogen 2.575 N/A VAL 149.A N VAL 145.A O no hydrogen 2.870 N/A ALA 150.A N GLN 146.A O no hydrogen 2.956 N/A GLU 151.A N GLU 147.A O no hydrogen 2.843 N/A GLU 152.A N LEU 148.A O no hydrogen 2.939 N/A VAL 153.A N VAL 149.A O no hydrogen 2.917 N/A ARG 154.A N ALA 150.A O no hydrogen 2.938 N/A ARG 154.A NH1 GLY 164.A O no hydrogen 2.315 N/A ASP 155.A N GLU 151.A O no hydrogen 2.864 N/A LEU 156.A N GLU 152.A O no hydrogen 2.876 N/A LEU 157.A N VAL 153.A O no hydrogen 2.950 N/A THR 158.A N ARG 154.A O no hydrogen 2.890 N/A THR 158.A OG1 ARG 154.A O no hydrogen 3.076 N/A THR 158.A OG1 ASP 155.A O no hydrogen 2.636 N/A SER 159.A N ASP 155.A O no hydrogen 2.894 N/A SER 159.A OG LEU 156.A O no hydrogen 2.478 N/A TYR 160.A N LEU 157.A O no hydrogen 3.243 N/A TYR 160.A OH ARG 116.A O no hydrogen 2.514 N/A GLY 161.A N THR 158.A O no hydrogen 2.945 N/A PHE 162.A N LEU 157.A O no hydrogen 2.897 N/A LYS 165.A NZ ASP 163.A OD1 no hydrogen 3.395 N/A LYS 165.A NZ ASN 166.A OD1 no hydrogen 3.384 N/A ASN 166.A N ASP 163.A O no hydrogen 2.752 N/A THR 167.A N GLY 164.A O no hydrogen 3.349 N/A THR 167.A OG1 GLY 164.A O no hydrogen 2.860 N/A ILE 170.A N VAL 132.A O no hydrogen 3.090 N/A LYS 176.A NZ ASP 138.A OD2 no hydrogen 3.256 N/A LEU 178.A N ALA 174.A O no hydrogen 2.895 N/A GLU 179.A N LEU 175.A O no hydrogen 2.910 N/A GLY 180.A N LYS 176.A O no hydrogen 3.043 N/A ASP 181.A N LYS 176.A O no hydrogen 2.941 N/A TRP 184.A N ASP 181.A O no hydrogen 3.203 N/A GLU 185.A N ASP 181.A O no hydrogen 3.008 N/A ALA 186.A N PRO 182.A O no hydrogen 2.905 N/A ILE 188.A N GLU 185.A O no hydrogen 3.250 N/A ASP 190.A N ALA 186.A O no hydrogen 2.904 N/A LEU 191.A N LYS 187.A O no hydrogen 2.873 N/A MET 192.A N ILE 188.A O no hydrogen 2.861 N/A ASN 193.A N HIS 189.A O no hydrogen 2.940 N/A ALA 194.A N ASP 190.A O no hydrogen 2.941 N/A VAL 195.A N LEU 191.A O no hydrogen 2.831 N/A ASP 196.A N MET 192.A O no hydrogen 2.915 N/A ASP 196.A N ASN 193.A O no hydrogen 3.190 N/A ALA 213.A N ARG 230.A O no hydrogen 2.907 N/A GLU 215.A N THR 228.A O no hydrogen 2.897 N/A MET 218.A N VAL 226.A O no hydrogen 2.527 N/A ILE 220.A N GLY 224.A O no hydrogen 3.012 N/A VAL 226.A N MET 218.A O no hydrogen 2.428 N/A VAL 227.A N VAL 276.A O no hydrogen 2.874 N/A THR 228.A N ASP 216.A O no hydrogen 3.498 N/A THR 228.A OG1 ALA 274.A O no hydrogen 2.863 N/A GLY 229.A N ALA 274.A O no hydrogen 2.878 N/A ARG 230.A N ALA 213.A O no hydrogen 2.900 N/A ARG 230.A NE GLU 232.A OE2 no hydrogen 2.486 N/A ARG 230.A NH2 GLU 232.A OE2 no hydrogen 3.033 N/A VAL 231.A N ASP 272.A O no hydrogen 2.559 N/A ARG 233.A NH1 GLU 369.A OE1 no hydrogen 2.867 N/A ARG 233.A NH2 GLU 369.A OE1 no hydrogen 3.444 N/A LEU 236.A N ALA 268.A O no hydrogen 2.744 N/A LYS 237.A NZ VAL 238.A O no hydrogen 3.444 N/A ILE 242.A N ALA 253.A O no hydrogen 2.933 N/A GLU 243.A N ALA 293.A O no hydrogen 2.570 N/A ILE 244.A N ARG 251.A O no hydrogen 2.849 N/A ARG 251.A N ILE 244.A O no hydrogen 3.011 N/A LYS 252.A NZ ILE 250.A O no hydrogen 3.411 N/A ALA 253.A N ILE 242.A O no hydrogen 2.878 N/A VAL 255.A N GLN 240.A O no hydrogen 3.055 N/A THR 256.A N LEU 277.A O no hydrogen 2.575 N/A GLY 257.A N LEU 277.A O no hydrogen 2.949 N/A GLU 259.A N GLY 275.A O no hydrogen 2.867 N/A MET 260.A N LYS 263.A O no hydrogen 2.771 N/A LEU 265.A N ILE 258.A O no hydrogen 2.872 N/A SER 267.A OG ASP 266.A O no hydrogen 2.764 N/A MET 269.A N ASP 272.A OD2 no hydrogen 2.571 N/A GLY 271.A N GLU 232.A O no hydrogen 3.055 N/A ASP 272.A N VAL 231.A O no hydrogen 3.120 N/A ALA 274.A N GLY 229.A O no hydrogen 2.898 N/A GLY 275.A N GLU 259.A O no hydrogen 2.864 N/A VAL 276.A N VAL 227.A O no hydrogen 2.877 N/A LEU 277.A N GLY 257.A O no hydrogen 2.865 N/A LEU 278.A N THR 225.A O no hydrogen 2.950 N/A ARG 279.A N VAL 254.A O no hydrogen 2.641 N/A LYS 284.A NZ LYS 284.A O no hydrogen 2.484 N/A LYS 284.A NZ GLU 287.A OE2 no hydrogen 3.382 N/A VAL 286.A N ASP 282.A O no hydrogen 3.092 N/A ARG 288.A NH2 ASN 90.A OD1 no hydrogen 2.681 N/A VAL 291.A N GLN 290.A OE1 no hydrogen 3.073 N/A ALA 293.A N GLU 243.A O no hydrogen 3.033 N/A LYS 294.A NZ PRO 209.A O no hydrogen 3.536 N/A LYS 294.A NZ GLN 240.A OE1 no hydrogen 3.381 N/A SER 297.A OG LYS 294.A O no hydrogen 3.293 N/A LYS 299.A NZ PRO 300.A O no hydrogen 3.097 N/A LYS 299.A NZ GLU 393.A OXT no hydrogen 3.410 N/A HIS 301.A N ILE 366.A O no hydrogen 2.587 N/A HIS 301.A ND1 GLU 393.A O no hydrogen 2.265 N/A LYS 302.A N GLU 393.A OE1 no hydrogen 3.028 N/A LYS 302.A NZ ILE 363.A O no hydrogen 3.000 N/A LYS 303.A N GLU 393.A OE1 no hydrogen 3.231 N/A LYS 303.A NZ LEU 392.A O no hydrogen 3.494 N/A PHE 304.A N VAL 360.A O no hydrogen 2.924 N/A LYS 305.A N GLU 390.A O no hydrogen 2.935 N/A ALA 306.A N ILE 358.A O no hydrogen 2.892 N/A GLU 307.A N SER 387.A O no hydrogen 3.489 N/A ILE 308.A N THR 356.A O no hydrogen 2.917 N/A TYR 309.A N ALA 385.A O no hydrogen 2.516 N/A ALA 310.A N GLY 353.A O no hydrogen 3.400 N/A LEU 311.A N VAL 383.A O no hydrogen 3.321 N/A LYS 312.A NZ GLU 314.A OE1 no hydrogen 3.132 N/A LYS 312.A NZ GLU 314.A OE2 no hydrogen 3.210 N/A LYS 313.A NZ LYS 313.A O no hydrogen 3.094 N/A GLU 315.A N LYS 312.A O no hydrogen 3.156 N/A GLY 316.A N LYS 313.A O no hydrogen 3.096 N/A ARG 318.A N LEU 311.A O no hydrogen 2.883 N/A ARG 318.A NE THR 320.A O no hydrogen 2.573 N/A ARG 318.A NH2 THR 320.A O no hydrogen 2.885 N/A PHE 322.A N VAL 350.A O no hydrogen 2.725 N/A ASN 324.A ND2 LEU 343.A O no hydrogen 3.422 N/A ASN 324.A ND2 GLU 348.A OE1 no hydrogen 2.813 N/A TYR 326.A OH GLU 378.A OE1 no hydrogen 3.164 N/A GLN 329.A N ARG 377.A O no hydrogen 2.663 N/A PHE 330.A N VAL 337.A O no hydrogen 2.403 N/A THR 334.A OG1 PHE 332.A O no hydrogen 3.036 N/A GLY 339.A N PRO 328.A O no hydrogen 3.138 N/A SER 340.A OG ASN 324.A O no hydrogen 2.875 N/A SER 340.A OG TYR 326.A O no hydrogen 2.982 N/A ILE 341.A N TYR 326.A O no hydrogen 3.173 N/A SER 342.A OG SER 342.A O no hydrogen 2.373 N/A SER 342.A OG THR 359.A O no hydrogen 2.225 N/A LEU 343.A N ILE 341.A O no hydrogen 2.878 N/A GLU 345.A N GLU 345.A OE2 no hydrogen 2.685 N/A THR 347.A N PRO 344.A O no hydrogen 3.124 N/A THR 347.A OG1 PRO 344.A O no hydrogen 2.467 N/A VAL 350.A N PHE 322.A O no hydrogen 2.974 N/A THR 356.A N ILE 308.A O no hydrogen 2.904 N/A THR 356.A OG1 ASP 354.A O no hydrogen 2.620 N/A ILE 358.A N ALA 306.A O no hydrogen 2.904 N/A VAL 360.A N PHE 304.A O no hydrogen 2.937 N/A LEU 362.A N LYS 302.A O no hydrogen 2.738 N/A ILE 363.A N THR 338.A O no hydrogen 3.123 N/A ILE 366.A N HIS 301.A O no hydrogen 2.952 N/A CYS 368.A SG ILE 366.A O no hydrogen 3.138 N/A SER 372.A OG GLU 369.A O no hydrogen 2.758 N/A PHE 374.A N GLY 386.A O no hydrogen 3.215 N/A ILE 376.A N GLY 384.A O no hydrogen 2.882 N/A ARG 377.A N GLN 329.A O no hydrogen 2.972 N/A ARG 377.A NH2 GLY 380.A O no hydrogen 2.761 N/A GLU 378.A N ARG 381.A O no hydrogen 2.921 N/A ARG 381.A N GLU 378.A O no hydrogen 2.933 N/A VAL 383.A N ILE 376.A O no hydrogen 2.857 N/A GLY 384.A N ILE 376.A O no hydrogen 3.049 N/A SER 387.A OG SER 372.A O no hydrogen 2.801 N/A VAL 388.A N SER 372.A O no hydrogen 3.346 N/A THR 389.A N LYS 305.A O no hydrogen 3.179 N/A THR 389.A OG1 SER 387.A O no hydrogen 3.517 N/A GLU 390.A N LYS 305.A O no hydrogen 2.874 N/A