Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7q43_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A NZ GLN 351.A OE1 no hydrogen 3.061 N/A VAL 3.A N SER 32.A OG no hydrogen 3.040 N/A PHE 4.A N ALA 365.A O no hydrogen 2.802 N/A VAL 5.A N SER 26.A O no hydrogen 2.912 N/A TRP 6.A N SER 363.A O no hydrogen 3.069 N/A TRP 6.A NE1 GLN 330.A O no hydrogen 2.776 N/A GLY 7.A N ILE 22.A O no hydrogen 2.829 N/A LEU 8.A N SER 361.A O no hydrogen 2.843 N/A ASN 9.A N SER 20.A O no hydrogen 2.682 N/A ASN 9.A ND2 LEU 17.A O no hydrogen 2.843 N/A ASN 9.A ND2 GLY 19.A O no hydrogen 2.837 N/A LYS 11.A N GLN 13.A OE1 no hydrogen 2.905 N/A ASP 12.A N ASN 9.A O no hydrogen 3.002 N/A GLN 13.A N GLN 13.A OE1 no hydrogen 2.661 N/A GLN 13.A NE2 ASP 10.A OD1 no hydrogen 2.956 N/A LEU 14.A N ASN 9.A OD1 no hydrogen 3.133 N/A GLY 15.A N ASP 12.A O no hydrogen 3.020 N/A LYS 21.A NZ ASP 327.A O no hydrogen 3.116 N/A LYS 21.A NZ HIS 328.A ND1 no hydrogen 3.157 N/A ILE 22.A N GLY 7.A O no hydrogen 2.895 N/A SER 26.A N VAL 5.A O no hydrogen 2.866 N/A SER 26.A OG VAL 24.A O no hydrogen 2.955 N/A SER 28.A N VAL 3.A O no hydrogen 2.887 N/A THR 30.A OG1 GLY 15.A O no hydrogen 2.750 N/A LEU 31.A N SER 28.A OG no hydrogen 3.121 N/A SER 32.A N SER 28.A O no hydrogen 3.130 N/A SER 32.A OG SER 28.A O no hydrogen 2.265 N/A ALA 33.A N GLU 29.A O no hydrogen 3.290 N/A LEU 34.A N LEU 31.A O no hydrogen 3.406 N/A VAL 37.A N VAL 49.A O no hydrogen 2.791 N/A GLN 38.A N VAL 49.A O no hydrogen 3.425 N/A GLN 38.A NE2 VAL 92.A O no hydrogen 2.772 N/A ALA 40.A N PHE 47.A O no hydrogen 2.849 N/A GLY 42.A N SER 45.A O no hydrogen 3.146 N/A SER 43.A N GLY 98.A O no hydrogen 3.183 N/A LYS 44.A N SER 360.A OG no hydrogen 3.157 N/A LYS 44.A NZ ASP 10.A OD2 no hydrogen 2.654 N/A LEU 46.A N CYS 58.A O no hydrogen 2.955 N/A PHE 47.A N ALA 40.A O no hydrogen 2.774 N/A ALA 48.A N TYR 56.A O no hydrogen 2.889 N/A VAL 49.A N GLN 38.A O no hydrogen 2.835 N/A THR 50.A N LYS 54.A O no hydrogen 2.897 N/A THR 50.A OG1 GLU 52.A OE2 no hydrogen 3.000 N/A VAL 51.A N ASN 35.A O no hydrogen 2.950 N/A GLY 53.A N THR 50.A O no hydrogen 3.114 N/A LYS 54.A N THR 50.A OG1 no hydrogen 2.963 N/A TYR 56.A N ALA 48.A O no hydrogen 2.981 N/A ALA 57.A N ARG 79.A O no hydrogen 2.850 N/A CYS 58.A N LEU 46.A O no hydrogen 2.955 N/A CYS 58.A SG GLN 13.A O no hydrogen 3.239 N/A GLY 59.A N VAL 75.A O no hydrogen 2.785 N/A GLU 60.A N LYS 44.A O no hydrogen 2.945 N/A ALA 61.A N GLY 73.A O no hydrogen 2.856 N/A THR 62.A OG1 GLU 60.A OE2 no hydrogen 2.641 N/A GLY 64.A N ALA 61.A O no hydrogen 3.057 N/A ARG 65.A N THR 62.A O no hydrogen 3.295 N/A ARG 65.A NE THR 62.A O no hydrogen 2.870 N/A ARG 65.A NH1 SER 43.A O no hydrogen 2.909 N/A ARG 65.A NH2 THR 62.A O no hydrogen 3.444 N/A ARG 65.A NH2 ASN 63.A OD1 no hydrogen 2.530 N/A GLY 67.A N GLY 64.A O no hydrogen 3.055 N/A GLY 69.A N ASP 130.A O no hydrogen 2.738 N/A VAL 75.A N GLY 59.A O no hydrogen 2.760 N/A ARG 79.A N ALA 57.A O no hydrogen 2.950 N/A ILE 81.A N VAL 55.A O no hydrogen 2.695 N/A LEU 84.A N ILE 81.A O no hydrogen 3.162 N/A SER 85.A N THR 82.A O no hydrogen 3.209 N/A SER 85.A OG THR 82.A O no hydrogen 2.873 N/A TYR 87.A N LEU 84.A O no hydrogen 3.059 N/A VAL 89.A N GLY 53.A O no hydrogen 3.056 N/A LYS 90.A N LEU 104.A O no hydrogen 2.737 N/A LYS 91.A N LEU 104.A O no hydrogen 3.326 N/A LYS 91.A NZ ASP 145.A OD1 no hydrogen 2.591 N/A LYS 91.A NZ ILE 146.A O no hydrogen 2.921 N/A VAL 92.A N GLN 38.A OE1 no hydrogen 2.815 N/A ALA 93.A N THR 102.A O no hydrogen 2.828 N/A HIS 95.A NE2 CYS 254.A O no hydrogen 3.085 N/A GLY 97.A N HIS 95.A ND1 no hydrogen 3.002 N/A GLY 98.A N HIS 95.A O no hydrogen 2.749 N/A ARG 99.A NE GLU 115.A OE1 no hydrogen 2.992 N/A ARG 99.A NE GLU 115.A OE2 no hydrogen 3.268 N/A ARG 99.A NH1 GLU 115.A OE1 no hydrogen 3.154 N/A HIS 100.A NE2 SER 153.A OG no hydrogen 2.834 N/A ALA 101.A N TRP 113.A O no hydrogen 3.057 N/A THR 102.A N ALA 93.A O no hydrogen 2.961 N/A ALA 103.A N PHE 111.A O no hydrogen 2.834 N/A LEU 104.A N LYS 91.A O no hydrogen 2.841 N/A THR 105.A N LYS 109.A O no hydrogen 2.818 N/A THR 105.A OG1 ASP 107.A OD1 no hydrogen 2.895 N/A THR 105.A OG1 LYS 109.A O no hydrogen 3.527 N/A VAL 106.A N VAL 88.A O no hydrogen 2.948 N/A GLY 108.A N THR 105.A O no hydrogen 2.840 N/A LYS 109.A N THR 105.A OG1 no hydrogen 2.837 N/A PHE 111.A N ALA 103.A O no hydrogen 3.012 N/A SER 112.A N ARG 133.A O no hydrogen 2.853 N/A SER 112.A OG LEU 121.A O no hydrogen 2.815 N/A SER 112.A OG HIS 123.A NE2 no hydrogen 2.908 N/A TRP 113.A N ALA 101.A O no hydrogen 3.164 N/A TRP 113.A NE1 ARG 65.A O no hydrogen 2.992 N/A GLY 114.A N CYS 129.A O no hydrogen 2.615 N/A GLU 115.A N ARG 99.A O no hydrogen 3.061 N/A GLY 116.A N ASN 128.A OD1 no hydrogen 2.503 N/A GLY 119.A N GLY 116.A O no hydrogen 3.046 N/A LYS 120.A N ASP 117.A O no hydrogen 3.253 N/A LYS 120.A NZ GLU 115.A OE1 no hydrogen 2.792 N/A LYS 120.A NZ SER 150.A O no hydrogen 2.868 N/A GLY 122.A N GLY 119.A O no hydrogen 3.062 N/A PHE 124.A N LEU 182.A O no hydrogen 3.142 N/A MET 127.A N SER 125.A OG no hydrogen 2.975 N/A CYS 129.A N GLY 114.A O no hydrogen 3.074 N/A ARG 133.A N SER 112.A O no hydrogen 2.817 N/A ILE 135.A N VAL 110.A O no hydrogen 2.872 N/A LEU 138.A N ILE 135.A O no hydrogen 3.110 N/A LYS 139.A N GLU 136.A O no hydrogen 3.105 N/A LYS 141.A N LEU 138.A O no hydrogen 2.957 N/A ILE 143.A N GLY 108.A O no hydrogen 3.433 N/A ARG 144.A N LEU 156.A O no hydrogen 2.845 N/A ARG 144.A NH1 VAL 195.A O no hydrogen 3.491 N/A ARG 144.A NH2 SER 158.A O no hydrogen 3.222 N/A ARG 144.A NH2 VAL 195.A O no hydrogen 3.458 N/A ALA 147.A N ALA 154.A O no hydrogen 3.207 N/A CYS 148.A SG ALA 93.A O no hydrogen 3.422 N/A CYS 148.A SG HIS 100.A NE2 no hydrogen 3.841 N/A CYS 148.A SG THR 102.A OG1 no hydrogen 3.597 N/A GLY 149.A N HIS 152.A O no hydrogen 2.773 N/A SER 150.A N GLY 201.A O no hydrogen 3.393 N/A HIS 152.A NE2 THR 207.A OG1 no hydrogen 2.949 N/A SER 153.A N TRP 165.A O no hydrogen 2.848 N/A SER 153.A OG HIS 100.A NE2 no hydrogen 2.834 N/A SER 153.A OG LYS 120.A O no hydrogen 2.865 N/A ALA 154.A N ALA 147.A O no hydrogen 2.888 N/A ALA 155.A N TYR 163.A O no hydrogen 2.882 N/A LEU 156.A N ASP 145.A O no hydrogen 3.049 N/A THR 157.A N GLU 161.A O no hydrogen 2.857 N/A THR 157.A OG1 GLU 161.A OE1 no hydrogen 3.180 N/A SER 158.A N ARG 142.A O no hydrogen 3.193 N/A GLY 160.A N THR 157.A O no hydrogen 3.008 N/A GLU 161.A N THR 157.A OG1 no hydrogen 3.059 N/A TYR 163.A N ALA 155.A O no hydrogen 2.853 N/A THR 164.A N LYS 185.A O no hydrogen 2.910 N/A THR 164.A OG1 LEU 173.A O no hydrogen 2.666 N/A TRP 165.A N SER 153.A O no hydrogen 3.121 N/A GLY 166.A N GLN 181.A O no hydrogen 2.704 N/A LEU 167.A N SER 151.A O no hydrogen 2.849 N/A GLY 168.A N THR 180.A OG1 no hydrogen 3.277 N/A GLY 171.A N GLY 168.A O no hydrogen 3.182 N/A ARG 172.A NE GLU 169.A O no hydrogen 2.995 N/A ARG 172.A NH1 ARG 203.A O no hydrogen 2.531 N/A ARG 172.A NH2 GLU 169.A O no hydrogen 2.853 N/A GLY 174.A N GLY 171.A O no hydrogen 3.125 N/A HIS 175.A NE2 LYS 185.A O no hydrogen 3.036 N/A GLY 176.A N ASN 236.A O no hydrogen 2.829 N/A THR 179.A N ASP 177.A OD1 no hydrogen 3.063 N/A GLN 181.A N GLY 166.A O no hydrogen 3.126 N/A LYS 185.A N THR 164.A O no hydrogen 2.856 N/A VAL 187.A N LEU 162.A O no hydrogen 2.713 N/A LEU 190.A N VAL 187.A O no hydrogen 3.222 N/A LEU 191.A N LYS 188.A O no hydrogen 3.304 N/A HIS 193.A N LEU 190.A O no hydrogen 3.012 N/A ARG 194.A NH2.A SER 158.A O no hydrogen 2.947 N/A VAL 195.A N GLY 160.A O no hydrogen 3.077 N/A ILE 196.A N LEU 210.A O no hydrogen 2.644 N/A GLN 197.A N LEU 210.A O no hydrogen 3.164 N/A GLN 197.A NE2 CYS 250.A O no hydrogen 3.562 N/A ALA 199.A N LEU 208.A O no hydrogen 2.714 N/A CYS 200.A SG HIS 152.A NE2 no hydrogen 3.502 N/A GLY 201.A N GLN 206.A O no hydrogen 2.751 N/A ARG 203.A N SER 150.A OG no hydrogen 3.065 N/A GLN 206.A N GLN 206.A OE1 no hydrogen 2.712 N/A GLN 206.A NE2 PHE 258.A O no hydrogen 3.084 N/A GLN 206.A NE2 SER 259.A OG no hydrogen 2.881 N/A THR 207.A N TRP 219.A O no hydrogen 2.760 N/A THR 207.A OG1 HIS 152.A NE2 no hydrogen 2.949 N/A THR 207.A OG1 ARG 172.A O no hydrogen 2.625 N/A LEU 208.A N ALA 199.A O no hydrogen 2.720 N/A ALA 209.A N PHE 217.A O no hydrogen 2.858 N/A LEU 210.A N GLN 197.A O no hydrogen 2.773 N/A THR 211.A N LEU 215.A O no hydrogen 2.978 N/A ASP 212.A N ARG 194.A O.A no hydrogen 3.109 N/A ASP 212.A N ARG 194.A O.B no hydrogen 3.155 N/A GLY 214.A N THR 211.A O no hydrogen 3.179 N/A LEU 215.A N THR 211.A OG1 no hydrogen 3.262 N/A PHE 217.A N ALA 209.A O no hydrogen 2.822 N/A SER 218.A N GLN 239.A O no hydrogen 2.911 N/A SER 218.A OG LEU 227.A O no hydrogen 2.663 N/A TRP 219.A N THR 207.A O no hydrogen 3.048 N/A GLY 220.A N CYS 235.A O no hydrogen 2.867 N/A ASP 221.A N ALA 205.A O no hydrogen 3.033 N/A ASP 223.A N ASP 221.A OD1 no hydrogen 2.755 N/A GLY 225.A N GLY 222.A O no hydrogen 3.203 N/A LYS 226.A NZ ASP 204.A O no hydrogen 3.282 N/A LYS 226.A NZ ASP 221.A OD1 no hydrogen 2.802 N/A LYS 226.A NZ ASP 223.A O no hydrogen 3.027 N/A LYS 226.A NZ GLN 257.A OE1 no hydrogen 2.475 N/A GLY 228.A N GLY 225.A O no hydrogen 2.892 N/A ARG 229.A NE GLU 242.A OE2 no hydrogen 3.173 N/A ARG 229.A NH2 GLU 242.A OE1 no hydrogen 3.064 N/A GLY 230.A N ARG 288.A O no hydrogen 2.748 N/A CYS 235.A N GLY 220.A O no hydrogen 3.239 N/A CYS 235.A SG ILE 237.A O no hydrogen 3.270 N/A GLN 239.A N SER 218.A O no hydrogen 2.989 N/A ILE 241.A N VAL 216.A O no hydrogen 2.807 N/A GLU 242.A N GLU 242.A OE2 no hydrogen 2.900 N/A ARG 243.A NH1 PRO 290.A O no hydrogen 2.832 N/A LEU 244.A N ILE 241.A O no hydrogen 3.158 N/A ASN 245.A N GLU 242.A O no hydrogen 3.124 N/A GLN 247.A N LEU 244.A O no hydrogen 3.217 N/A GLN 247.A NE2 ASN 245.A O no hydrogen 3.670 N/A CYS 250.A N LEU 262.A O no hydrogen 2.685 N/A CYS 250.A SG LEU 262.A O no hydrogen 3.639 N/A GLN 251.A N LEU 262.A O no hydrogen 3.164 N/A GLN 251.A NE2 GLU 253.A OE2 no hydrogen 2.877 N/A GLN 251.A NE2 VAL 304.A O no hydrogen 3.085 N/A ILE 252.A N GLN 197.A OE1 no hydrogen 2.950 N/A GLU 253.A N LEU 260.A O no hydrogen 2.831 N/A GLY 255.A N PHE 258.A O no hydrogen 3.000 N/A ALA 256.A N ALA 308.A O no hydrogen 3.028 N/A GLN 257.A NE2 ASP 204.A O no hydrogen 3.014 N/A SER 259.A N TRP 271.A O no hydrogen 2.864 N/A SER 259.A OG LYS 226.A O no hydrogen 3.001 N/A LEU 260.A N GLU 253.A O no hydrogen 3.004 N/A ALA 261.A N TRP 269.A O no hydrogen 2.997 N/A LEU 262.A N GLN 251.A O no hydrogen 2.855 N/A THR 263.A N VAL 267.A O no hydrogen 2.957 N/A THR 263.A OG1 VAL 267.A O no hydrogen 3.472 N/A LYS 264.A N GLY 248.A O no hydrogen 2.873 N/A LYS 264.A NZ GLY 248.A O no hydrogen 3.495 N/A LYS 264.A NZ VAL 249.A O no hydrogen 3.152 N/A GLY 266.A N THR 263.A O no hydrogen 2.737 N/A VAL 267.A N THR 263.A OG1 no hydrogen 2.996 N/A TRP 269.A N ALA 261.A O no hydrogen 2.944 N/A THR 270.A N GLN 291.A O no hydrogen 3.038 N/A THR 270.A OG1 LEU 279.A O no hydrogen 2.783 N/A THR 270.A OG1 HIS 281.A NE2 no hydrogen 2.540 N/A TRP 271.A N SER 259.A O no hydrogen 3.065 N/A GLY 272.A N VAL 287.A O no hydrogen 2.651 N/A LYS 273.A N GLN 257.A O no hydrogen 2.921 N/A GLY 274.A N HIS 286.A ND1 no hydrogen 2.971 N/A PHE 277.A N GLY 274.A O no hydrogen 3.046 N/A ARG 278.A NE ASP 275.A O no hydrogen 2.778 N/A ARG 278.A NH1 ALA 256.A O no hydrogen 2.927 N/A ARG 278.A NH2 ASP 275.A O no hydrogen 2.853 N/A GLY 280.A N PHE 277.A O no hydrogen 3.102 N/A GLY 282.A N ARG 340.A O no hydrogen 3.187 N/A VAL 287.A N GLY 272.A O no hydrogen 3.153 N/A ARG 288.A NH1 GLY 231.A O no hydrogen 3.193 N/A GLN 291.A N THR 270.A O no hydrogen 3.281 N/A VAL 293.A N VAL 268.A O no hydrogen 2.603 N/A LEU 296.A N VAL 293.A O no hydrogen 2.966 N/A ARG 297.A N GLU 294.A O no hydrogen 3.237 N/A LYS 299.A N LEU 296.A O no hydrogen 2.888 N/A ILE 301.A N GLY 266.A O no hydrogen 3.294 N/A VAL 302.A N VAL 314.A O no hydrogen 2.710 N/A ALA 305.A N LEU 312.A O no hydrogen 2.677 N/A GLY 307.A N HIS 310.A O no hydrogen 2.834 N/A ALA 308.A N SER 360.A O no hydrogen 3.416 N/A HIS 310.A NE2 HIS 362.A O no hydrogen 3.104 N/A CYS 311.A N TRP 323.A O no hydrogen 3.052 N/A CYS 311.A SG ARG 278.A O no hydrogen 3.603 N/A LEU 312.A N ALA 305.A O no hydrogen 2.922 N/A ALA 313.A N TYR 321.A O no hydrogen 2.881 N/A VAL 314.A N HIS 303.A O no hydrogen 2.738 N/A THR 315.A N GLN 319.A O no hydrogen 2.897 N/A THR 315.A OG1 SER 317.A OG no hydrogen 2.663 N/A ASP 316.A N LYS 300.A O no hydrogen 2.939 N/A SER 317.A N THR 315.A OG1 no hydrogen 3.107 N/A SER 317.A OG THR 315.A OG1 no hydrogen 2.663 N/A GLY 318.A N THR 315.A O no hydrogen 3.051 N/A GLN 319.A N THR 315.A OG1 no hydrogen 3.269 N/A TYR 321.A N ALA 313.A O no hydrogen 2.846 N/A ALA 322.A N THR 343.A O no hydrogen 2.989 N/A TRP 323.A N CYS 311.A O no hydrogen 3.295 N/A TRP 323.A NE1 ARG 278.A O no hydrogen 2.962 N/A GLY 324.A N ASN 339.A O no hydrogen 2.787 N/A ASP 325.A N LEU 309.A O no hydrogen 2.996 N/A ASN 326.A ND2 ASN 333.A OD1 no hydrogen 3.102 N/A ASN 326.A ND2 THR 335.A O no hydrogen 2.830 N/A ASN 326.A ND2 THR 337.A O no hydrogen 2.788 N/A HIS 328.A N GLN 330.A OE1 no hydrogen 3.030 N/A GLY 329.A N ASN 326.A O no hydrogen 3.223 N/A GLN 330.A N GLN 330.A OE1 no hydrogen 2.838 N/A GLN 331.A N ASN 326.A OD1 no hydrogen 2.770 N/A GLN 331.A NE2 ASP 325.A O no hydrogen 2.781 N/A GLY 332.A N GLY 329.A O no hydrogen 2.967 N/A ASN 333.A ND2 THR 337.A O no hydrogen 3.303 N/A ASN 333.A ND2 ASN 339.A OD1 no hydrogen 2.986 N/A GLY 334.A N LYS 23.A O no hydrogen 2.837 N/A THR 335.A N ASN 333.A OD1 no hydrogen 2.996 N/A THR 335.A OG1 ASN 333.A OD1 no hydrogen 2.369 N/A THR 337.A N THR 335.A OG1 no hydrogen 3.288 N/A ASN 339.A N GLY 324.A O no hydrogen 3.171 N/A ASN 339.A ND2 GLN 331.A OE1 no hydrogen 3.002 N/A THR 343.A N ALA 322.A O no hydrogen 2.771 N/A THR 343.A OG1 LYS 341.A O no hydrogen 2.865 N/A VAL 345.A N VAL 320.A O no hydrogen 2.858 N/A GLN 351.A N LEU 348.A O no hydrogen 2.939 N/A ILE 353.A N GLY 318.A O no hydrogen 3.033 N/A THR 354.A N TRP 366.A O no hydrogen 3.034 N/A THR 354.A OG1 TRP 366.A O no hydrogen 3.398 N/A ARG 355.A N TRP 366.A O no hydrogen 3.329 N/A ARG 355.A NH2 HIS 303.A NE2 no hydrogen 3.489 N/A VAL 356.A N HIS 303.A ND1 no hydrogen 3.149 N/A ALA 357.A N VAL 364.A O no hydrogen 2.833 N/A CYS 358.A SG HIS 310.A NE2 no hydrogen 3.489 N/A GLY 359.A N HIS 362.A O no hydrogen 3.097 N/A SER 360.A N GLY 42.A O no hydrogen 3.095 N/A HIS 362.A NE2 SER 45.A O no hydrogen 2.805 N/A SER 363.A N TRP 6.A O no hydrogen 2.940 N/A SER 363.A OG HIS 310.A NE2 no hydrogen 3.267 N/A SER 363.A OG GLN 330.A O no hydrogen 2.772 N/A VAL 364.A N ALA 357.A O no hydrogen 2.837 N/A ALA 365.A N PHE 4.A O no hydrogen 2.879 N/A TRP 366.A N ARG 355.A O no hydrogen 3.033 N/A THR 367.A N LYS 2.A O no hydrogen 3.199 N/A THR 367.A OG1 LYS 352.A O no hydrogen 2.785 N/A