Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7q45_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A N THR 368.A OG1 no hydrogen 3.190 N/A VAL 4.A N SER 33.A OG no hydrogen 2.988 N/A PHE 5.A N ALA 366.A O no hydrogen 2.708 N/A VAL 6.A N SER 27.A O no hydrogen 2.961 N/A TRP 7.A N SER 364.A O no hydrogen 3.012 N/A GLY 8.A N ILE 23.A O no hydrogen 2.738 N/A LEU 9.A N SER 362.A O no hydrogen 2.980 N/A ASN 10.A N SER 21.A O no hydrogen 2.674 N/A ASN 10.A ND2 LEU 18.A O no hydrogen 2.834 N/A ASN 10.A ND2 GLY 20.A O no hydrogen 2.958 N/A LYS 12.A N GLN 14.A OE1 no hydrogen 2.781 N/A ASP 13.A N ASN 10.A O no hydrogen 3.183 N/A GLN 14.A N GLN 14.A OE1 no hydrogen 2.693 N/A GLN 14.A NE2 ASP 11.A OD1 no hydrogen 3.098 N/A LEU 15.A N ASN 10.A OD1 no hydrogen 3.060 N/A GLY 16.A N ASP 13.A O no hydrogen 3.181 N/A LYS 22.A NZ ASP 328.A O no hydrogen 3.385 N/A LYS 22.A NZ HIS 329.A ND1 no hydrogen 3.115 N/A ILE 23.A N GLY 8.A O no hydrogen 2.959 N/A LYS 24.A NZ LYS 22.A O no hydrogen 3.469 N/A SER 27.A N VAL 6.A O no hydrogen 2.900 N/A SER 27.A OG VAL 25.A O no hydrogen 2.812 N/A SER 29.A N VAL 4.A O no hydrogen 2.819 N/A THR 31.A OG1 GLY 16.A O no hydrogen 3.122 N/A THR 31.A OG1 SER 29.A OG no hydrogen 3.311 N/A LEU 32.A N SER 29.A OG no hydrogen 3.210 N/A SER 33.A N SER 29.A O no hydrogen 2.766 N/A SER 33.A OG SER 29.A O no hydrogen 2.523 N/A ALA 34.A N GLU 30.A O no hydrogen 3.041 N/A LEU 35.A N LEU 32.A O no hydrogen 3.161 N/A ASN 36.A N SER 33.A O no hydrogen 3.517 N/A VAL 37.A N THR 2.A OG1 no hydrogen 3.090 N/A VAL 38.A N VAL 50.A O no hydrogen 2.712 N/A GLN 39.A N VAL 50.A O no hydrogen 3.197 N/A GLN 39.A NE2 VAL 93.A O no hydrogen 2.906 N/A ALA 41.A N PHE 48.A O no hydrogen 2.782 N/A GLY 43.A N SER 46.A O no hydrogen 3.001 N/A SER 44.A N GLY 99.A O no hydrogen 3.145 N/A LYS 45.A N SER 361.A OG no hydrogen 3.077 N/A LYS 45.A NZ ASP 11.A OD2 no hydrogen 2.704 N/A SER 46.A N GLY 43.A O no hydrogen 3.422 N/A LEU 47.A N CYS 59.A O no hydrogen 3.044 N/A PHE 48.A N ALA 41.A O no hydrogen 2.785 N/A ALA 49.A N TYR 57.A O no hydrogen 2.751 N/A VAL 50.A N GLN 39.A O no hydrogen 2.753 N/A THR 51.A N LYS 55.A O no hydrogen 2.997 N/A VAL 52.A N ASN 36.A O no hydrogen 3.019 N/A GLY 54.A N THR 51.A O no hydrogen 2.842 N/A LYS 55.A N THR 51.A OG1 no hydrogen 3.202 N/A LYS 55.A NZ GLU 53.A OE2 no hydrogen 2.894 N/A TYR 57.A N ALA 49.A O no hydrogen 2.756 N/A ALA 58.A N ARG 80.A O no hydrogen 2.951 N/A CYS 59.A N LEU 47.A O no hydrogen 2.985 N/A CYS 59.A SG GLN 14.A O no hydrogen 3.780 N/A GLY 60.A N VAL 76.A O no hydrogen 2.823 N/A GLU 61.A N LYS 45.A O no hydrogen 2.976 N/A ALA 62.A N GLY 74.A O no hydrogen 2.944 N/A THR 63.A OG1 GLU 61.A OE2 no hydrogen 2.562 N/A THR 63.A OG1 SER 73.A O no hydrogen 3.280 N/A GLY 65.A N ALA 62.A O no hydrogen 2.988 N/A ARG 66.A N THR 63.A O no hydrogen 3.059 N/A ARG 66.A NE ASN 64.A OD1 no hydrogen 3.434 N/A GLY 68.A N GLY 65.A O no hydrogen 3.419 N/A GLY 70.A N ASP 131.A O no hydrogen 2.879 N/A VAL 76.A N GLY 60.A O no hydrogen 2.898 N/A ARG 80.A N ALA 58.A O no hydrogen 2.815 N/A GLN 81.A NE2 TYR 57.A OH no hydrogen 3.203 N/A ILE 82.A N VAL 56.A O no hydrogen 2.821 N/A LEU 85.A N ILE 82.A O no hydrogen 3.119 N/A SER 86.A N THR 83.A O no hydrogen 3.185 N/A SER 86.A OG THR 83.A O no hydrogen 2.951 N/A TYR 88.A N LEU 85.A O no hydrogen 2.985 N/A VAL 90.A N GLY 54.A O no hydrogen 2.783 N/A LYS 91.A N LEU 105.A O no hydrogen 2.681 N/A LYS 92.A N LEU 105.A O no hydrogen 3.239 N/A LYS 92.A NZ ASP 146.A OD1 no hydrogen 2.814 N/A VAL 93.A N GLN 39.A OE1 no hydrogen 2.902 N/A ALA 94.A N THR 103.A O no hydrogen 2.934 N/A GLY 98.A N HIS 96.A ND1 no hydrogen 2.910 N/A GLY 99.A N HIS 96.A O no hydrogen 2.891 N/A ARG 100.A NE GLU 116.A OE1 no hydrogen 3.111 N/A ARG 100.A NE GLU 116.A OE2 no hydrogen 2.972 N/A ARG 100.A NH1 GLU 116.A OE1 no hydrogen 3.210 N/A HIS 101.A NE2 SER 154.A OG no hydrogen 2.840 N/A ALA 102.A N TRP 114.A O no hydrogen 3.021 N/A THR 103.A N ALA 94.A O no hydrogen 3.018 N/A ALA 104.A N PHE 112.A O no hydrogen 2.785 N/A LEU 105.A N LYS 92.A O no hydrogen 2.879 N/A THR 106.A N LYS 110.A O no hydrogen 2.907 N/A THR 106.A OG1 ASP 108.A OD1 no hydrogen 2.532 N/A VAL 107.A N VAL 89.A O no hydrogen 2.983 N/A ASP 108.A N ASP 108.A OD1 no hydrogen 2.481 N/A GLY 109.A N THR 106.A O no hydrogen 3.011 N/A LYS 110.A N THR 106.A OG1 no hydrogen 3.021 N/A PHE 112.A N ALA 104.A O no hydrogen 2.934 N/A SER 113.A N ARG 134.A O no hydrogen 2.964 N/A SER 113.A OG LEU 122.A O no hydrogen 2.620 N/A TRP 114.A N ALA 102.A O no hydrogen 3.050 N/A TRP 114.A NE1 ARG 66.A O no hydrogen 2.668 N/A GLY 115.A N CYS 130.A O no hydrogen 2.652 N/A GLU 116.A N ARG 100.A O no hydrogen 2.941 N/A GLY 117.A N ASN 129.A OD1 no hydrogen 2.674 N/A GLY 120.A N GLY 117.A O no hydrogen 3.202 N/A LYS 121.A N ASP 118.A O no hydrogen 3.433 N/A LYS 121.A NZ GLU 116.A OE1 no hydrogen 2.689 N/A LYS 121.A NZ SER 151.A O no hydrogen 2.973 N/A GLY 123.A N GLY 120.A O no hydrogen 2.955 N/A PHE 125.A N LEU 183.A O no hydrogen 2.994 N/A ARG 127.A NH1 ASP 119.A OD1 no hydrogen 3.526 N/A MET 128.A N SER 126.A OG no hydrogen 3.199 N/A CYS 130.A N GLY 115.A O no hydrogen 2.990 N/A ARG 134.A N SER 113.A O no hydrogen 2.837 N/A ILE 136.A N VAL 111.A O no hydrogen 2.929 N/A LEU 139.A N ILE 136.A O no hydrogen 3.192 N/A LYS 140.A N GLU 137.A O no hydrogen 2.913 N/A LYS 140.A NZ GLU 137.A OE2 no hydrogen 3.209 N/A LYS 142.A N LEU 139.A O no hydrogen 3.070 N/A ARG 145.A N LEU 157.A O no hydrogen 2.708 N/A ASP 146.A N LEU 157.A O no hydrogen 3.394 N/A ILE 147.A N ASP 146.A OD1 no hydrogen 2.746 N/A ALA 148.A N ALA 155.A O no hydrogen 3.003 N/A CYS 149.A SG ALA 94.A O no hydrogen 3.516 N/A CYS 149.A SG HIS 101.A NE2 no hydrogen 3.647 N/A CYS 149.A SG THR 103.A OG1 no hydrogen 3.408 N/A GLY 150.A N HIS 153.A O no hydrogen 2.819 N/A SER 151.A N GLY 202.A O no hydrogen 3.161 N/A SER 151.A OG SER 152.A OG no hydrogen 3.113 N/A SER 152.A OG SER 151.A OG no hydrogen 3.113 N/A HIS 153.A NE2 THR 208.A OG1 no hydrogen 2.914 N/A SER 154.A N TRP 166.A O no hydrogen 2.829 N/A SER 154.A OG HIS 101.A NE2 no hydrogen 2.840 N/A SER 154.A OG LYS 121.A O no hydrogen 2.729 N/A ALA 155.A N ALA 148.A O no hydrogen 2.807 N/A ALA 156.A N TYR 164.A O no hydrogen 3.005 N/A LEU 157.A N ASP 146.A O no hydrogen 2.985 N/A THR 158.A N GLU 162.A O no hydrogen 2.964 N/A THR 158.A OG1 SER 160.A OG no hydrogen 2.743 N/A SER 159.A N ARG 143.A O no hydrogen 2.970 N/A SER 160.A OG THR 158.A OG1 no hydrogen 2.743 N/A GLY 161.A N THR 158.A O no hydrogen 2.877 N/A GLU 162.A N THR 158.A OG1 no hydrogen 3.248 N/A TYR 164.A N ALA 156.A O no hydrogen 2.760 N/A THR 165.A N LYS 186.A O no hydrogen 2.960 N/A THR 165.A OG1 LEU 174.A O no hydrogen 2.659 N/A THR 165.A OG1 HIS 176.A NE2 no hydrogen 2.829 N/A TRP 166.A N SER 154.A O no hydrogen 3.061 N/A GLY 167.A N GLN 182.A O no hydrogen 2.729 N/A LEU 168.A N SER 152.A O no hydrogen 2.916 N/A GLY 169.A N THR 181.A OG1 no hydrogen 3.155 N/A GLY 172.A N GLY 169.A O no hydrogen 3.079 N/A ARG 173.A NE GLU 170.A O no hydrogen 2.968 N/A ARG 173.A NH1 ARG 204.A O no hydrogen 2.664 N/A ARG 173.A NH2 GLU 170.A O no hydrogen 3.064 N/A ARG 173.A NH2 ARG 204.A O no hydrogen 3.390 N/A GLY 175.A N GLY 172.A O no hydrogen 3.312 N/A GLY 177.A N ASN 237.A O no hydrogen 2.860 N/A THR 180.A N ASP 178.A OD1 no hydrogen 2.902 N/A GLN 182.A N GLY 167.A O no hydrogen 3.036 N/A LYS 186.A N THR 165.A O no hydrogen 3.020 N/A VAL 188.A N LEU 163.A O no hydrogen 2.877 N/A LYS 189.A NZ MET 187.A O no hydrogen 3.087 N/A LEU 191.A N VAL 188.A O no hydrogen 3.166 N/A LEU 192.A N LYS 189.A O no hydrogen 3.231 N/A HIS 194.A N LEU 191.A O no hydrogen 2.990 N/A VAL 196.A N GLY 161.A O no hydrogen 3.019 N/A ILE 197.A N LEU 211.A O no hydrogen 2.666 N/A GLN 198.A N LEU 211.A O no hydrogen 3.326 N/A ALA 200.A N LEU 209.A O no hydrogen 2.788 N/A GLY 202.A N GLN 207.A O no hydrogen 2.926 N/A ARG 204.A N SER 151.A OG no hydrogen 2.900 N/A GLN 207.A N GLN 207.A OE1 no hydrogen 2.640 N/A GLN 207.A NE2 PHE 259.A O no hydrogen 3.061 N/A GLN 207.A NE2 SER 260.A OG no hydrogen 3.016 N/A THR 208.A N TRP 220.A O no hydrogen 2.873 N/A THR 208.A OG1 HIS 153.A NE2 no hydrogen 2.914 N/A THR 208.A OG1 ARG 173.A O no hydrogen 2.734 N/A LEU 209.A N ALA 200.A O no hydrogen 2.774 N/A ALA 210.A N PHE 218.A O no hydrogen 2.901 N/A LEU 211.A N GLN 198.A O no hydrogen 2.956 N/A THR 212.A N LEU 216.A O no hydrogen 2.864 N/A ASP 213.A N ARG 195.A O no hydrogen 2.860 N/A GLU 214.A N THR 212.A OG1 no hydrogen 3.303 N/A GLY 215.A N THR 212.A O no hydrogen 2.993 N/A LEU 216.A N THR 212.A OG1 no hydrogen 3.239 N/A PHE 218.A N ALA 210.A O no hydrogen 2.792 N/A SER 219.A N GLN 240.A O no hydrogen 2.876 N/A SER 219.A OG LEU 228.A O no hydrogen 2.640 N/A TRP 220.A N THR 208.A O no hydrogen 3.081 N/A GLY 221.A N CYS 236.A O no hydrogen 2.597 N/A ASP 222.A N ALA 206.A O no hydrogen 2.870 N/A ASP 224.A N ASP 222.A OD2 no hydrogen 3.056 N/A GLY 226.A N GLY 223.A O no hydrogen 3.132 N/A LYS 227.A N ASP 224.A O no hydrogen 3.420 N/A LYS 227.A NZ ASP 222.A O no hydrogen 3.507 N/A LYS 227.A NZ ASP 222.A OD2 no hydrogen 2.595 N/A LYS 227.A NZ ASP 224.A O no hydrogen 2.940 N/A LYS 227.A NZ GLN 258.A OE1 no hydrogen 2.949 N/A GLY 229.A N GLY 226.A O no hydrogen 3.072 N/A ARG 230.A NE ASN 241.A O no hydrogen 3.162 N/A ARG 230.A NH2 GLU 243.A OE1 no hydrogen 3.061 N/A GLY 231.A N ARG 289.A O no hydrogen 2.841 N/A CYS 236.A N GLY 221.A O no hydrogen 2.964 N/A CYS 236.A SG ILE 238.A O no hydrogen 3.425 N/A ASN 237.A ND2 ASN 179.A OD1 no hydrogen 3.618 N/A GLN 240.A N SER 219.A O no hydrogen 3.058 N/A ASN 241.A ND2 VAL 217.A O no hydrogen 2.922 N/A ASN 241.A ND2 ASN 246.A OD1 no hydrogen 3.053 N/A ILE 242.A N VAL 217.A O no hydrogen 2.810 N/A GLU 243.A N GLU 243.A OE2 no hydrogen 2.787 N/A LEU 245.A N ILE 242.A O no hydrogen 3.232 N/A ASN 246.A N GLU 243.A O no hydrogen 3.058 N/A ASN 246.A ND2 ASN 241.A OD1 no hydrogen 2.790 N/A GLN 248.A N LEU 245.A O no hydrogen 3.125 N/A GLN 248.A NE2 ASN 246.A O no hydrogen 3.545 N/A CYS 251.A N LEU 263.A O no hydrogen 2.783 N/A CYS 251.A SG LEU 263.A O no hydrogen 3.632 N/A GLN 252.A N LEU 263.A O no hydrogen 3.210 N/A GLN 252.A NE2 GLU 254.A OE2 no hydrogen 2.780 N/A GLN 252.A NE2 VAL 305.A O no hydrogen 3.070 N/A ILE 253.A N GLN 198.A OE1 no hydrogen 3.244 N/A GLU 254.A N LEU 261.A O no hydrogen 2.973 N/A GLY 256.A N PHE 259.A O no hydrogen 3.018 N/A ALA 257.A N ALA 309.A O no hydrogen 3.261 N/A GLN 258.A NE2 SER 203.A O no hydrogen 3.097 N/A GLN 258.A NE2 ASP 205.A O no hydrogen 2.952 N/A SER 260.A N TRP 272.A O no hydrogen 2.753 N/A SER 260.A OG LYS 227.A O no hydrogen 2.833 N/A LEU 261.A N GLU 254.A O no hydrogen 3.051 N/A ALA 262.A N TRP 270.A O no hydrogen 2.829 N/A LEU 263.A N GLN 252.A O no hydrogen 2.838 N/A THR 264.A N VAL 268.A O no hydrogen 2.942 N/A THR 264.A OG1 SER 266.A OG no hydrogen 3.333 N/A THR 264.A OG1 VAL 268.A O no hydrogen 3.546 N/A LYS 265.A N GLY 249.A O no hydrogen 2.844 N/A SER 266.A OG THR 264.A OG1 no hydrogen 3.333 N/A GLY 267.A N THR 264.A O no hydrogen 2.935 N/A VAL 268.A N THR 264.A OG1 no hydrogen 3.046 N/A TRP 270.A N ALA 262.A O no hydrogen 2.791 N/A THR 271.A N GLN 292.A O no hydrogen 3.051 N/A THR 271.A OG1 LEU 280.A O no hydrogen 2.769 N/A THR 271.A OG1 HIS 282.A NE2 no hydrogen 2.754 N/A TRP 272.A N SER 260.A O no hydrogen 3.070 N/A GLY 273.A N VAL 288.A O no hydrogen 2.645 N/A LYS 274.A N GLN 258.A O no hydrogen 2.900 N/A GLY 275.A N HIS 287.A ND1 no hydrogen 2.970 N/A PHE 278.A N GLY 275.A O no hydrogen 3.057 N/A ARG 279.A NE ASP 276.A O no hydrogen 2.921 N/A ARG 279.A NH1 ALA 257.A O no hydrogen 2.707 N/A ARG 279.A NH2 ASP 276.A O no hydrogen 3.043 N/A GLY 283.A N ARG 341.A O no hydrogen 3.176 N/A VAL 288.A N GLY 273.A O no hydrogen 3.078 N/A ARG 289.A NH1 GLY 232.A O no hydrogen 2.989 N/A GLN 292.A N THR 271.A O no hydrogen 3.077 N/A GLN 292.A NE2 HIS 282.A ND1 no hydrogen 3.062 N/A VAL 294.A N VAL 269.A O no hydrogen 2.763 N/A LEU 297.A N VAL 294.A O no hydrogen 3.182 N/A ARG 298.A N GLU 295.A O no hydrogen 2.937 N/A ARG 298.A NE GLU 295.A OE2 no hydrogen 3.471 N/A ARG 298.A NH2 GLU 295.A OE1 no hydrogen 2.454 N/A LYS 300.A N LEU 297.A O no hydrogen 2.985 N/A ILE 302.A N GLY 267.A O no hydrogen 3.282 N/A VAL 303.A N VAL 315.A O no hydrogen 2.781 N/A ALA 306.A N LEU 313.A O no hydrogen 2.890 N/A GLY 308.A N HIS 311.A O no hydrogen 2.743 N/A ALA 309.A N SER 361.A O no hydrogen 3.382 N/A HIS 311.A NE2 HIS 363.A O no hydrogen 3.189 N/A CYS 312.A N TRP 324.A O no hydrogen 3.033 N/A CYS 312.A SG ARG 279.A O no hydrogen 3.517 N/A LEU 313.A N ALA 306.A O no hydrogen 2.825 N/A ALA 314.A N TYR 322.A O no hydrogen 2.896 N/A VAL 315.A N HIS 304.A O no hydrogen 2.858 N/A THR 316.A N GLN 320.A O no hydrogen 2.781 N/A THR 316.A OG1 SER 318.A OG no hydrogen 3.006 N/A THR 316.A OG1 GLN 320.A O no hydrogen 3.520 N/A ASP 317.A N LYS 301.A O no hydrogen 2.835 N/A SER 318.A N THR 316.A OG1 no hydrogen 3.345 N/A SER 318.A OG THR 316.A OG1 no hydrogen 3.006 N/A GLY 319.A N THR 316.A O no hydrogen 3.005 N/A GLN 320.A N THR 316.A OG1 no hydrogen 3.096 N/A TYR 322.A N ALA 314.A O no hydrogen 2.763 N/A ALA 323.A N THR 344.A O no hydrogen 2.898 N/A TRP 324.A N CYS 312.A O no hydrogen 3.251 N/A TRP 324.A NE1 ARG 279.A O no hydrogen 3.025 N/A GLY 325.A N ASN 340.A O no hydrogen 2.848 N/A ASP 326.A N LEU 310.A O no hydrogen 3.006 N/A ASN 327.A ND2 ASN 334.A OD1 no hydrogen 2.982 N/A ASN 327.A ND2 THR 338.A O no hydrogen 2.837 N/A ASP 328.A N ASP 326.A OD2 no hydrogen 3.302 N/A HIS 329.A N GLN 331.A OE1 no hydrogen 2.930 N/A GLY 330.A N ASN 327.A O no hydrogen 3.254 N/A GLN 331.A N GLN 331.A OE1 no hydrogen 2.827 N/A GLN 332.A N ASN 327.A OD1 no hydrogen 2.825 N/A GLN 332.A NE2 ASP 326.A O no hydrogen 2.885 N/A GLY 333.A N GLY 330.A O no hydrogen 2.984 N/A ASN 334.A ND2 THR 338.A O no hydrogen 3.025 N/A ASN 334.A ND2 ASN 340.A OD1 no hydrogen 2.990 N/A GLY 335.A N LYS 24.A O no hydrogen 2.950 N/A THR 336.A N ASN 334.A OD1 no hydrogen 2.921 N/A THR 336.A OG1 ASN 334.A OD1 no hydrogen 2.682 N/A THR 338.A N THR 336.A OG1 no hydrogen 2.931 N/A ASN 340.A N GLY 325.A O no hydrogen 3.104 N/A ASN 340.A ND2 ALA 323.A O no hydrogen 3.390 N/A ASN 340.A ND2 GLN 332.A OE1 no hydrogen 2.786 N/A THR 344.A N ALA 323.A O no hydrogen 2.867 N/A THR 344.A OG1 LYS 342.A O no hydrogen 2.867 N/A VAL 346.A N VAL 321.A O no hydrogen 2.846 N/A GLN 347.A N GLY 333.A O no hydrogen 3.159 N/A GLN 352.A N LEU 349.A O no hydrogen 2.863 N/A THR 355.A N TRP 367.A O no hydrogen 3.078 N/A THR 355.A OG1 TRP 367.A O no hydrogen 3.478 N/A ARG 356.A N TRP 367.A O no hydrogen 3.292 N/A ARG 356.A NH1 THR 355.A O no hydrogen 2.996 N/A VAL 357.A N HIS 304.A ND1 no hydrogen 3.174 N/A ALA 358.A N VAL 365.A O no hydrogen 2.893 N/A CYS 359.A SG HIS 311.A NE2 no hydrogen 3.454 N/A GLY 360.A N HIS 363.A O no hydrogen 3.032 N/A SER 361.A N GLY 43.A O no hydrogen 3.190 N/A HIS 363.A NE2 SER 46.A O no hydrogen 2.865 N/A SER 364.A N TRP 7.A O no hydrogen 2.733 N/A SER 364.A OG HIS 311.A NE2 no hydrogen 2.964 N/A SER 364.A OG GLN 331.A O no hydrogen 2.887 N/A VAL 365.A N ALA 358.A O no hydrogen 2.761 N/A ALA 366.A N PHE 5.A O no hydrogen 2.873 N/A TRP 367.A N ARG 356.A O no hydrogen 3.016 N/A THR 368.A N LYS 3.A O no hydrogen 3.048 N/A