Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7qg5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 2.A N LEU 73.A O no hydrogen 2.907 N/A PHE 4.A N PHE 75.A O no hydrogen 2.862 N/A SER 5.A N GLU 8.A OE2 no hydrogen 3.219 N/A SER 5.A OG GLU 8.A OE2 no hydrogen 3.173 N/A GLU 8.A N SER 5.A OG no hydrogen 3.145 N/A LEU 9.A N SER 5.A O no hydrogen 3.296 N/A LYS 10.A N PHE 6.A O no hydrogen 2.866 N/A ASN 11.A N TYR 7.A O no hydrogen 2.999 N/A VAL 12.A N GLU 8.A O no hydrogen 3.042 N/A THR 13.A OG1 LEU 9.A O no hydrogen 2.829 N/A THR 13.A OG1 LYS 10.A O no hydrogen 3.149 N/A ASN 14.A N ASN 11.A O no hydrogen 3.220 N/A ASN 14.A ND2 ASN 22.A OD1 no hydrogen 2.933 N/A ASN 15.A N LYS 10.A O no hydrogen 2.779 N/A PHE 16.A N THR 13.A OG1 no hydrogen 3.018 N/A ASP 17.A N THR 13.A O no hydrogen 3.060 N/A ARG 19.A N ASP 17.A OD1 no hydrogen 2.843 N/A ASN 22.A ND2 LYS 34.A O no hydrogen 2.944 N/A LYS 23.A N ARG 19.A O no hydrogen 3.091 N/A MET 24.A N VAL 32.A O no hydrogen 2.873 N/A VAL 31.A N LYS 46.A O no hydrogen 3.204 N/A VAL 32.A N GLY 25.A O no hydrogen 2.906 N/A TYR 33.A N VAL 44.A O no hydrogen 2.870 N/A LYS 34.A N ASN 22.A O no hydrogen 2.857 N/A LYS 34.A NZ TYR 36.A OH no hydrogen 3.453 N/A GLY 35.A N VAL 42.A O no hydrogen 2.911 N/A VAL 37.A N THR 40.A O no hydrogen 3.109 N/A VAL 42.A N GLY 35.A O no hydrogen 2.859 N/A ALA 43.A N TYR 80.A O no hydrogen 2.912 N/A VAL 44.A N TYR 33.A O no hydrogen 2.843 N/A LYS 45.A N LEU 78.A O no hydrogen 2.834 N/A LYS 46.A N VAL 31.A O no hydrogen 2.903 N/A LYS 51.A NZ ASP 55.A OD1 no hydrogen 3.065 N/A LYS 51.A NZ ASP 55.A OD2 no hydrogen 3.478 N/A GLN 52.A N GLU 48.A O no hydrogen 3.003 N/A GLN 53.A N GLU 49.A O no hydrogen 3.105 N/A PHE 54.A N LEU 50.A O no hydrogen 3.052 N/A ASP 55.A N LYS 51.A O no hydrogen 2.989 N/A GLN 56.A N GLN 52.A O no hydrogen 2.955 N/A GLU 57.A N GLN 53.A O no hydrogen 3.055 N/A ILE 58.A N PHE 54.A O no hydrogen 3.232 N/A LYS 59.A N ASP 55.A O no hydrogen 2.952 N/A LYS 59.A NZ GLN 56.A OE1 no hydrogen 3.261 N/A VAL 60.A N GLN 56.A O no hydrogen 2.905 N/A MET 61.A N GLU 57.A O no hydrogen 3.063 N/A ALA 62.A N ILE 58.A O no hydrogen 2.893 N/A LYS 63.A N LYS 59.A O no hydrogen 3.359 N/A CYS 64.A N VAL 60.A O no hydrogen 2.807 N/A CYS 64.A SG HIS 125.A ND1 no hydrogen 4.029 N/A ASN 68.A N HIS 66.A ND1 no hydrogen 2.983 N/A ASN 68.A ND2 ALA 143.A O no hydrogen 2.903 N/A LEU 69.A N HIS 66.A O no hydrogen 3.080 N/A VAL 70.A N ILE 145.A O no hydrogen 2.963 N/A LEU 73.A N VAL 79.A O no hydrogen 2.747 N/A GLY 74.A N VAL 79.A O no hydrogen 3.178 N/A PHE 75.A N HIS 2.A O no hydrogen 3.075 N/A SER 76.A N CYS 77.A O no hydrogen 2.970 N/A SER 76.A OG PHE 4.A O no hydrogen 2.647 N/A LEU 78.A N LYS 45.A O no hydrogen 2.996 N/A VAL 79.A N GLY 74.A O no hydrogen 2.854 N/A TYR 80.A N ALA 43.A O no hydrogen 2.891 N/A VAL 81.A N GLU 71.A O no hydrogen 3.439 N/A TYR 82.A N THR 41.A O no hydrogen 3.382 N/A ASN 85.A N LEU 137.A O no hydrogen 2.931 N/A ASN 85.A ND2 ASP 138.A O no hydrogen 2.846 N/A GLY 86.A N MET 83.A O no hydrogen 3.224 N/A LEU 88.A N ILE 135.A O no hydrogen 2.846 N/A LEU 89.A N SER 132.A O no hydrogen 3.216 N/A ASP 90.A N SER 87.A OG no hydrogen 3.242 N/A ARG 91.A N SER 87.A O no hydrogen 3.005 N/A ARG 91.A NE THR 98.A OG1 no hydrogen 2.871 N/A ARG 91.A NH1 LEU 95.A O no hydrogen 2.935 N/A ARG 91.A NH2 ASN 85.A O no hydrogen 2.952 N/A LEU 92.A N LEU 88.A O no hydrogen 2.803 N/A SER 93.A N LEU 89.A O no hydrogen 3.154 N/A SER 93.A OG LEU 89.A O no hydrogen 3.498 N/A SER 93.A OG ASP 90.A O no hydrogen 3.317 N/A CYS 94.A N ARG 91.A O no hydrogen 3.242 N/A CYS 94.A SG ARG 91.A O no hydrogen 3.932 N/A LEU 95.A N ASP 90.A O no hydrogen 2.940 N/A GLY 97.A N CYS 94.A O no hydrogen 3.121 N/A THR 98.A OG1 LEU 95.A O no hydrogen 3.448 N/A TRP 103.A N ASP 230.A OD1 no hydrogen 2.871 N/A TRP 103.A NE1 SER 235.A OG no hydrogen 2.509 N/A HIS 104.A N ASP 230.A OD2 no hydrogen 3.084 N/A MET 105.A N SER 102.A OG no hydrogen 3.050 N/A ARG 106.A N SER 102.A O no hydrogen 2.912 N/A ARG 106.A NE LEU 101.A O no hydrogen 2.936 N/A ARG 106.A NH1 ILE 190.A O no hydrogen 2.863 N/A ARG 106.A NH1 ASP 225.A OD2 no hydrogen 2.879 N/A ARG 106.A NH2 LEU 101.A O no hydrogen 2.998 N/A ARG 106.A NH2 ASP 225.A OD2 no hydrogen 2.962 N/A CYS 107.A N TRP 103.A O no hydrogen 2.929 N/A CYS 107.A SG TRP 103.A O no hydrogen 3.416 N/A LYS 108.A N HIS 104.A O no hydrogen 3.319 N/A ILE 109.A N MET 105.A O no hydrogen 2.927 N/A ALA 110.A N ARG 106.A O no hydrogen 2.915 N/A GLN 111.A N CYS 107.A O no hydrogen 3.001 N/A GLN 111.A NE2 LEU 264.A O no hydrogen 2.887 N/A GLN 111.A NE2 THR 268.A OG1 no hydrogen 2.613 N/A GLY 112.A N LYS 108.A O no hydrogen 2.888 N/A ALA 113.A N ILE 109.A O no hydrogen 2.897 N/A ALA 114.A N ALA 110.A O no hydrogen 3.108 N/A ASN 115.A N GLN 111.A O no hydrogen 2.964 N/A GLY 116.A N GLY 112.A O no hydrogen 2.992 N/A ILE 117.A N ALA 113.A O no hydrogen 2.979 N/A ASN 118.A N ALA 114.A O no hydrogen 2.845 N/A ASN 118.A ND2 GLU 122.A OE2 no hydrogen 3.208 N/A PHE 119.A N ASN 115.A O no hydrogen 3.019 N/A LEU 120.A N GLY 116.A O no hydrogen 3.087 N/A HIS 121.A N ILE 117.A O no hydrogen 2.899 N/A HIS 121.A NE2 ASP 179.A OD2 no hydrogen 2.837 N/A GLU 122.A N ASN 118.A O no hydrogen 2.845 N/A ASN 123.A N PHE 119.A O no hydrogen 3.130 N/A ASN 123.A ND2 PHE 119.A O no hydrogen 2.811 N/A HIS 124.A N HIS 121.A O no hydrogen 3.000 N/A HIS 125.A N LEU 120.A O no hydrogen 2.891 N/A HIS 125.A ND1 ASN 123.A O no hydrogen 3.003 N/A ILE 126.A N ARG 152.A O no hydrogen 2.889 N/A HIS 127.A N ASP 179.A OD2 no hydrogen 2.791 N/A HIS 127.A NE2 SER 146.A O no hydrogen 2.744 N/A ARG 128.A N ASP 179.A OD1 no hydrogen 3.023 N/A ARG 128.A NE LEU 150.A O no hydrogen 3.178 N/A ARG 128.A NH2 LEU 150.A O no hydrogen 2.985 N/A ASP 129.A N HIS 127.A ND1 no hydrogen 2.976 N/A LYS 131.A NZ THR 161.A OG1 no hydrogen 2.957 N/A SER 132.A OG TYR 164.A OH no hydrogen 3.338 N/A SER 132.A OG GLU 189.A OE1 no hydrogen 3.057 N/A SER 132.A OG GLU 189.A OE2 no hydrogen 2.911 N/A ASN 134.A N LYS 131.A O no hydrogen 2.977 N/A ASN 134.A ND2 ASP 129.A O no hydrogen 2.843 N/A ILE 135.A N SER 132.A O no hydrogen 3.321 N/A LEU 136.A N LYS 144.A O no hydrogen 2.840 N/A LEU 137.A N GLY 86.A O no hydrogen 2.792 N/A ASP 138.A N THR 142.A O no hydrogen 3.265 N/A ALA 140.A N ASP 138.A OD1 no hydrogen 2.869 N/A PHE 141.A N ASP 138.A O no hydrogen 2.997 N/A THR 142.A N ASP 138.A OD1 no hydrogen 2.974 N/A LYS 144.A N LEU 136.A O no hydrogen 2.814 N/A LYS 144.A NZ GLU 67.A O no hydrogen 2.779 N/A ILE 145.A N ASN 68.A O no hydrogen 2.843 N/A SER 146.A N ASN 134.A O no hydrogen 2.839 N/A SER 146.A OG ASN 134.A O no hydrogen 3.312 N/A PHE 148.A N GLU 57.A OE2 no hydrogen 3.266 N/A ALA 151.A N PHE 148.A O no hydrogen 3.258 N/A ARG 152.A N ILE 126.A O no hydrogen 2.937 N/A THR 161.A OG1 ASP 129.A OD1 no hydrogen 2.791 N/A TYR 164.A N THR 161.A O no hydrogen 3.007 N/A TYR 164.A OH SER 132.A OG no hydrogen 3.338 N/A TYR 164.A OH GLU 189.A OE1 no hydrogen 2.969 N/A TYR 164.A OH GLU 189.A OE2 no hydrogen 2.990 N/A MET 165.A N THR 162.A O no hydrogen 3.189 N/A GLU 168.A N GLU 168.A OE1 no hydrogen 2.892 N/A LEU 170.A N ALA 166.A O no hydrogen 3.165 N/A ARG 171.A N PRO 167.A O no hydrogen 3.242 N/A ARG 171.A N GLU 168.A O no hydrogen 3.206 N/A GLY 172.A N ALA 169.A O no hydrogen 3.229 N/A GLU 173.A N GLU 168.A O no hydrogen 2.931 N/A ILE 174.A N VAL 155.A O no hydrogen 2.811 N/A LYS 177.A N THR 175.A OG1 no hydrogen 3.125 N/A SER 178.A N THR 175.A O no hydrogen 3.042 N/A SER 178.A OG GLU 168.A OE2 no hydrogen 2.793 N/A ILE 180.A N PRO 176.A O no hydrogen 3.326 N/A TYR 181.A N LYS 177.A O no hydrogen 3.200 N/A SER 182.A N SER 178.A O no hydrogen 3.088 N/A SER 182.A OG TYR 164.A O no hydrogen 2.571 N/A SER 182.A OG SER 178.A O no hydrogen 3.308 N/A PHE 183.A N ASP 179.A O no hydrogen 2.927 N/A GLY 184.A N ILE 180.A O no hydrogen 2.980 N/A VAL 185.A N TYR 181.A O no hydrogen 3.269 N/A VAL 186.A N SER 182.A O no hydrogen 3.128 N/A LEU 187.A N PHE 183.A O no hydrogen 2.879 N/A LEU 188.A N GLY 184.A O no hydrogen 3.135 N/A GLU 189.A N VAL 185.A O no hydrogen 2.987 N/A ILE 190.A N VAL 186.A O no hydrogen 2.918 N/A ILE 191.A N LEU 187.A O no hydrogen 2.966 N/A THR 192.A N LEU 188.A O no hydrogen 2.951 N/A THR 192.A OG1 LEU 188.A O no hydrogen 2.783 N/A GLY 193.A N GLU 189.A O no hydrogen 2.788 N/A LEU 194.A N THR 192.A OG1 no hydrogen 3.122 N/A ASP 198.A N GLN 204.A O no hydrogen 2.998 N/A HIS 200.A N ASP 198.A OD1 no hydrogen 2.888 N/A ARG 201.A N ASP 198.A O no hydrogen 3.237 N/A ARG 201.A NE PRO 203.A O no hydrogen 2.869 N/A ARG 201.A NH1 PRO 195.A O no hydrogen 2.902 N/A ARG 201.A NH2 PRO 195.A O no hydrogen 2.974 N/A ARG 201.A NH2 GLN 204.A O no hydrogen 2.840 N/A LEU 206.A N ALA 196.A O no hydrogen 2.893 N/A ASP 208.A N LEU 205.A O no hydrogen 3.155 N/A ILE 209.A N LEU 206.A O no hydrogen 2.947 N/A LYS 210.A N LEU 207.A O no hydrogen 3.255 N/A LYS 210.A NZ GLU 211.A OE1 no hydrogen 3.355 N/A LYS 210.A NZ GLU 214.A OE1 no hydrogen 2.946 N/A LYS 210.A NZ GLU 214.A OE2 no hydrogen 3.239 N/A GLU 211.A N ASP 208.A O no hydrogen 3.235 N/A GLU 212.A N ASP 208.A O no hydrogen 3.302 N/A ILE 213.A N ILE 209.A O no hydrogen 2.917 N/A GLU 214.A N LYS 210.A O no hydrogen 3.017 N/A ASP 215.A N GLU 211.A O no hydrogen 2.886 N/A GLU 216.A N ILE 213.A O no hydrogen 3.183 N/A GLU 217.A N GLU 212.A O no hydrogen 2.919 N/A LYS 218.A N GLU 212.A O no hydrogen 3.323 N/A THR 219.A N ASP 222.A OD2 no hydrogen 3.241 N/A ASP 222.A N THR 219.A O no hydrogen 3.205 N/A TYR 223.A N ILE 220.A O no hydrogen 2.895 N/A TYR 223.A OH GLU 212.A OE2 no hydrogen 2.642 N/A ILE 224.A N ILE 220.A O no hydrogen 3.015 N/A ASP 225.A N ILE 191.A O no hydrogen 2.888 N/A LYS 227.A N ASP 225.A OD1 no hydrogen 3.007 N/A LYS 227.A NZ ASP 225.A OD1 no hydrogen 2.818 N/A LYS 227.A NZ ASP 225.A OD2 no hydrogen 3.474 N/A SER 233.A OG GLU 221.A OE2 no hydrogen 3.142 N/A SER 235.A N ASP 232.A OD2 no hydrogen 3.053 N/A SER 235.A OG ASP 232.A O no hydrogen 3.381 N/A SER 235.A OG ASP 232.A OD1 no hydrogen 2.597 N/A VAL 236.A N ASP 232.A O no hydrogen 3.000 N/A GLU 237.A N SER 233.A O no hydrogen 2.841 N/A ALA 238.A N THR 234.A O no hydrogen 2.960 N/A MET 239.A N SER 235.A O no hydrogen 2.953 N/A TYR 240.A N VAL 236.A O no hydrogen 2.869 N/A SER 241.A N GLU 237.A O no hydrogen 2.885 N/A VAL 242.A N ALA 238.A O no hydrogen 3.237 N/A ALA 243.A N MET 239.A O no hydrogen 2.973 N/A SER 244.A N TYR 240.A O no hydrogen 2.797 N/A GLN 245.A N SER 241.A O no hydrogen 3.036 N/A CYS 246.A N VAL 242.A O no hydrogen 2.938 N/A CYS 246.A SG VAL 242.A O no hydrogen 3.209 N/A LEU 247.A N ALA 243.A O no hydrogen 2.932 N/A LEU 247.A N SER 244.A O no hydrogen 3.170 N/A HIS 248.A N GLN 245.A O no hydrogen 3.439 N/A LYS 251.A NZ GLU 173.A OE1 no hydrogen 3.140 N/A LYS 253.A N LYS 250.A O no hydrogen 3.019 N/A ARG 254.A N LYS 251.A O no hydrogen 3.264 N/A ARG 254.A NE HIS 248.A O no hydrogen 2.767 N/A ARG 254.A NH1 GLU 168.A OE1 no hydrogen 3.478 N/A ARG 254.A NH1 GLU 168.A OE2 no hydrogen 2.779 N/A ARG 254.A NH1 LYS 177.A O no hydrogen 2.942 N/A ARG 254.A NH2 GLU 168.A OE1 no hydrogen 2.844 N/A ARG 254.A NH2 HIS 248.A O no hydrogen 3.211 N/A ARG 254.A NH2 GLU 249.A O no hydrogen 3.434 N/A LYS 258.A NZ GLN 261.A OE1 no hydrogen 3.087 N/A LYS 259.A N ASP 256.A OD1 no hydrogen 2.959 N/A VAL 260.A N ASP 256.A O no hydrogen 3.091 N/A GLN 261.A N ILE 257.A O no hydrogen 2.853 N/A GLN 261.A NE2 ASN 115.A OD1 no hydrogen 2.830 N/A GLN 262.A N LYS 258.A O no hydrogen 2.947 N/A LEU 263.A N LYS 259.A O no hydrogen 2.884 N/A LEU 264.A N VAL 260.A O no hydrogen 2.960 N/A GLN 265.A N GLN 261.A O no hydrogen 3.141 N/A GLU 266.A N GLN 262.A O no hydrogen 2.987 N/A MET 267.A N LEU 263.A O no hydrogen 3.179 N/A THR 268.A N GLN 265.A O no hydrogen 3.337 N/A THR 268.A OG1 GLN 265.A O no hydrogen 3.452 N/A