Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7s46_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 2.A NE2 ASP 90.A OD1 no hydrogen 2.747 N/A PHE 5.A N SER 1.A O no hydrogen 3.134 N/A ARG 6.A N HIS 2.A O no hydrogen 2.911 N/A ARG 6.A NE GLY 89.A O no hydrogen 2.971 N/A ARG 6.A NH1 GLU 3.A OE1 no hydrogen 3.529 N/A ARG 6.A NH2 GLY 89.A O no hydrogen 2.987 N/A ALA 7.A N GLU 3.A O no hydrogen 3.210 N/A ALA 8.A N GLN 4.A O no hydrogen 3.248 N/A LEU 9.A N PHE 5.A O no hydrogen 3.026 N/A GLN 10.A N ARG 6.A O no hydrogen 2.870 N/A GLN 10.A NE2 GLN 10.A O no hydrogen 3.215 N/A LEU 11.A N ALA 7.A O no hydrogen 3.293 N/A LEU 11.A N ALA 8.A O no hydrogen 3.113 N/A VAL 12.A N LEU 9.A O no hydrogen 3.046 N/A VAL 13.A N LEU 9.A O no hydrogen 3.250 N/A ASP 14.A N SER 85.A O no hydrogen 2.795 N/A ARG 19.A N ASP 17.A OD1 no hydrogen 2.907 N/A ARG 19.A NE ASP 17.A OD1 no hydrogen 3.142 N/A ARG 19.A NE ASP 17.A OD2 no hydrogen 3.163 N/A ARG 19.A NH2 ASP 17.A OD2 no hydrogen 2.541 N/A SER 20.A N ASP 17.A O no hydrogen 3.217 N/A SER 20.A OG ASP 17.A O no hydrogen 2.817 N/A TYR 21.A N PRO 18.A O no hydrogen 2.918 N/A TYR 21.A OH TYR 86.A OH no hydrogen 2.618 N/A LEU 22.A N PRO 18.A O no hydrogen 3.081 N/A ASP 23.A N THR 40.A O no hydrogen 2.747 N/A ILE 26.A N ILE 38.A O no hydrogen 2.971 N/A LYS 27.A NZ GLU 30.A OE1 no hydrogen 3.195 N/A ILE 28.A N VAL 36.A O no hydrogen 2.792 N/A GLY 31.A N GLY 34.A O no hydrogen 2.830 N/A ILE 35.A N LYS 52.A O no hydrogen 2.980 N/A VAL 36.A N GLY 29.A O no hydrogen 2.951 N/A CYS 37.A N VAL 50.A O no hydrogen 3.015 N/A ILE 38.A N ILE 26.A O no hydrogen 2.847 N/A ALA 39.A N VAL 48.A O no hydrogen 2.944 N/A THR 40.A N ASP 23.A O no hydrogen 2.825 N/A VAL 41.A N LYS 46.A O no hydrogen 2.722 N/A ARG 42.A N TYR 21.A O no hydrogen 2.892 N/A ARG 42.A NE ASP 23.A OD1 no hydrogen 3.027 N/A ARG 42.A NE ASP 23.A OD2 no hydrogen 3.273 N/A ARG 42.A NH1 SER 20.A O no hydrogen 2.544 N/A ARG 42.A NH2 ARG 19.A O no hydrogen 3.322 N/A ARG 42.A NH2 ASP 23.A OD1 no hydrogen 2.765 N/A SER 44.A N VAL 41.A O no hydrogen 3.449 N/A GLY 45.A N VAL 41.A O no hydrogen 2.774 N/A LYS 46.A N SER 44.A OG no hydrogen 3.232 N/A VAL 48.A N ALA 39.A O no hydrogen 2.975 N/A ALA 49.A N MET 96.A O no hydrogen 2.921 N/A VAL 50.A N CYS 37.A O no hydrogen 2.902 N/A LYS 51.A N VAL 94.A O no hydrogen 2.750 N/A LYS 51.A NZ GLU 67.A OE2 no hydrogen 2.867 N/A LYS 51.A NZ ASP 159.A OD1 no hydrogen 3.240 N/A LYS 52.A N ILE 35.A O no hydrogen 2.881 N/A MET 53.A N LEU 92.A O no hydrogen 2.879 N/A LEU 55.A N ASP 90.A O no hydrogen 2.942 N/A ARG 56.A N ASP 54.A OD1 no hydrogen 2.890 N/A ARG 56.A NE ASP 54.A OD1 no hydrogen 3.058 N/A ARG 56.A NH2 ASP 54.A OD1 no hydrogen 3.469 N/A ARG 56.A NH2 ASP 54.A OD2 no hydrogen 2.742 N/A LYS 57.A N ASP 54.A O no hydrogen 3.227 N/A GLN 58.A NE2 THR 33.A O no hydrogen 2.910 N/A GLN 58.A NE2 ASP 54.A O no hydrogen 2.861 N/A ARG 60.A NE GLU 62.A OE2 no hydrogen 3.079 N/A ARG 60.A NH2 GLU 62.A OE2 no hydrogen 3.397 N/A GLU 62.A N GLU 62.A OE1 no hydrogen 2.934 N/A LEU 63.A N ARG 60.A O no hydrogen 3.244 N/A LEU 64.A N ARG 61.A O no hydrogen 2.853 N/A PHE 65.A N GLU 62.A O no hydrogen 3.341 N/A ASN 66.A N LEU 63.A O no hydrogen 2.824 N/A ASN 66.A ND2 GLY 161.A O no hydrogen 3.188 N/A ASN 66.A ND2 CYS 163.A O no hydrogen 2.851 N/A VAL 69.A N PHE 65.A O no hydrogen 2.950 N/A ILE 70.A N ASN 66.A O no hydrogen 3.058 N/A MET 71.A N GLU 67.A O no hydrogen 3.380 N/A ARG 72.A N VAL 68.A O no hydrogen 3.062 N/A ARG 72.A NH2 VAL 12.A O no hydrogen 3.075 N/A ASP 73.A N ILE 70.A O no hydrogen 3.246 N/A TYR 74.A N ILE 70.A O no hydrogen 2.823 N/A ASN 78.A N HIS 76.A ND1 no hydrogen 3.043 N/A ASN 78.A ND2 VAL 155.A O no hydrogen 3.059 N/A VAL 79.A N HIS 76.A O no hydrogen 3.018 N/A VAL 80.A N LEU 157.A O no hydrogen 2.972 N/A GLU 81.A N GLU 97.A OE1 no hydrogen 2.883 N/A TYR 83.A N VAL 95.A O no hydrogen 2.792 N/A ASN 84.A N VAL 95.A O no hydrogen 3.294 N/A ASN 84.A ND2 ASP 14.A OD2 no hydrogen 2.915 N/A SER 85.A N ASP 14.A OD2 no hydrogen 3.027 N/A TYR 86.A N TRP 93.A O no hydrogen 2.805 N/A TYR 86.A OH TYR 21.A OH no hydrogen 2.618 N/A VAL 88.A N GLU 91.A O no hydrogen 2.819 N/A GLU 91.A N VAL 88.A O no hydrogen 3.024 N/A LEU 92.A N MET 53.A O no hydrogen 2.880 N/A TRP 93.A N TYR 86.A O no hydrogen 2.837 N/A TRP 93.A NE1 GLU 91.A OE1 no hydrogen 2.892 N/A VAL 94.A N LYS 51.A O no hydrogen 2.796 N/A VAL 95.A N ASN 84.A O no hydrogen 2.905 N/A MET 96.A N ALA 49.A O no hydrogen 2.804 N/A GLU 97.A N GLU 81.A O no hydrogen 2.813 N/A GLY 101.A N LEU 149.A O no hydrogen 2.919 N/A GLY 102.A N LEU 99.A O no hydrogen 3.043 N/A LEU 104.A N ILE 147.A O no hydrogen 2.852 N/A THR 105.A OG1 SER 144.A OG no hydrogen 2.755 N/A ASP 106.A N ALA 103.A O no hydrogen 3.215 N/A VAL 108.A N LEU 104.A O no hydrogen 3.027 N/A THR 109.A N THR 105.A O no hydrogen 3.099 N/A THR 109.A OG1 THR 105.A O no hydrogen 2.759 N/A THR 109.A OG1 ASP 106.A O no hydrogen 3.250 N/A THR 109.A OG1 HIS 110.A ND1 no hydrogen 3.342 N/A HIS 110.A N ILE 107.A O no hydrogen 3.118 N/A HIS 110.A ND1 ASP 106.A O no hydrogen 2.907 N/A THR 111.A N ILE 107.A O no hydrogen 2.870 N/A THR 111.A OG1 ILE 107.A O no hydrogen 3.282 N/A ASN 114.A N GLN 117.A OE1 no hydrogen 2.895 N/A GLN 117.A N ASN 114.A OD1 no hydrogen 3.049 N/A GLN 117.A NE2 SER 281.A O no hydrogen 2.821 N/A ILE 118.A N ASN 114.A O no hydrogen 3.002 N/A ALA 119.A N GLU 115.A O no hydrogen 2.983 N/A ALA 120.A N GLU 116.A O no hydrogen 3.087 N/A VAL 121.A N GLN 117.A O no hydrogen 2.938 N/A CYS 122.A N ILE 118.A O no hydrogen 2.894 N/A CYS 122.A SG ILE 118.A O no hydrogen 3.455 N/A LEU 123.A N ALA 119.A O no hydrogen 2.808 N/A ALA 124.A N ALA 120.A O no hydrogen 3.023 N/A VAL 125.A N VAL 121.A O no hydrogen 2.980 N/A LEU 126.A N CYS 122.A O no hydrogen 2.863 N/A GLN 127.A N LEU 123.A O no hydrogen 2.966 N/A ALA 128.A N ALA 124.A O no hydrogen 3.255 N/A LEU 129.A N VAL 125.A O no hydrogen 2.816 N/A SER 130.A N LEU 126.A O no hydrogen 2.792 N/A SER 130.A OG LEU 126.A O no hydrogen 3.034 N/A SER 130.A OG GLN 127.A O no hydrogen 2.703 N/A VAL 131.A N GLN 127.A O no hydrogen 3.441 N/A LEU 132.A N ALA 128.A O no hydrogen 2.961 N/A HIS 133.A N LEU 129.A O no hydrogen 2.787 N/A HIS 133.A NE2 ASP 198.A OD2 no hydrogen 2.734 N/A ALA 134.A N SER 130.A O no hydrogen 3.123 N/A GLN 135.A N LEU 132.A O no hydrogen 3.102 N/A GLN 135.A NE2 VAL 131.A O no hydrogen 3.548 N/A GLY 136.A N HIS 133.A O no hydrogen 3.060 N/A VAL 137.A N LEU 132.A O no hydrogen 3.049 N/A ILE 138.A N ALA 164.A O no hydrogen 2.922 N/A HIS 139.A N ASP 198.A OD2 no hydrogen 2.840 N/A HIS 139.A NE2 SER 158.A O no hydrogen 2.771 N/A ARG 140.A N ASP 198.A OD1 no hydrogen 2.802 N/A ARG 140.A NE PHE 162.A O no hydrogen 2.746 N/A ARG 140.A NH1 GLU 175.A OE1 no hydrogen 2.946 N/A ARG 140.A NH1 TYR 193.A OH no hydrogen 2.968 N/A ARG 140.A NH2 PHE 162.A O no hydrogen 2.972 N/A ASN 141.A N HIS 139.A ND1 no hydrogen 3.177 N/A ASN 141.A ND2 ASP 159.A OD2 no hydrogen 3.057 N/A LYS 143.A NZ THR 179.A OG1 no hydrogen 2.829 N/A SER 144.A N GLU 208.A OE1 no hydrogen 2.951 N/A SER 144.A OG THR 105.A OG1 no hydrogen 2.755 N/A SER 144.A OG GLU 208.A OE1 no hydrogen 3.475 N/A SER 144.A OG GLU 208.A OE2 no hydrogen 2.442 N/A SER 146.A N LYS 143.A O no hydrogen 2.948 N/A SER 146.A OG ASN 141.A O no hydrogen 2.799 N/A ILE 147.A N SER 144.A O no hydrogen 3.216 N/A LEU 148.A N LYS 156.A O no hydrogen 2.860 N/A LEU 149.A N GLY 102.A O no hydrogen 2.974 N/A THR 150.A N ARG 154.A O no hydrogen 2.920 N/A THR 150.A OG1 ASP 152.A OD1 no hydrogen 2.406 N/A HIS 151.A N GLU 100.A OE1 no hydrogen 2.754 N/A GLY 153.A N THR 150.A O no hydrogen 3.043 N/A ARG 154.A N THR 150.A OG1 no hydrogen 2.848 N/A ARG 154.A NH2 ASP 152.A OD2 no hydrogen 2.505 N/A LYS 156.A N LEU 148.A O no hydrogen 2.869 N/A LYS 156.A NZ GLU 97.A OE1 no hydrogen 3.437 N/A LYS 156.A NZ GLU 97.A OE2 no hydrogen 2.763 N/A LEU 157.A N ASN 78.A O no hydrogen 2.703 N/A SER 158.A N SER 146.A O no hydrogen 2.746 N/A GLY 161.A N ASP 159.A OD1 no hydrogen 3.418 N/A CYS 163.A N PHE 160.A O no hydrogen 3.225 N/A CYS 163.A SG PHE 160.A O no hydrogen 3.222 N/A ALA 164.A N ILE 138.A O no hydrogen 3.074 N/A VAL 166.A N GLY 136.A O no hydrogen 2.679 N/A SER 167.A N VAL 170.A O no hydrogen 2.971 N/A SER 167.A OG GLU 169.A OE1 no hydrogen 3.437 N/A VAL 170.A N SER 167.A OG no hydrogen 3.236 N/A ARG 172.A NH1 GLU 196.A OE1 no hydrogen 3.193 N/A ARG 172.A NH1 GLU 196.A OE2 no hydrogen 3.390 N/A ARG 172.A NH2 GLU 196.A OE2 no hydrogen 2.658 N/A ARG 173.A N TYR 193.A O no hydrogen 2.870 N/A ARG 173.A NE GLU 175.A OE1 no hydrogen 3.221 N/A ARG 173.A NH1 GLN 165.A O no hydrogen 2.827 N/A ARG 173.A NH2 GLU 175.A OE1 no hydrogen 3.453 N/A ARG 173.A NH2 GLU 175.A OE2 no hydrogen 2.818 N/A THR 179.A OG1 ASN 141.A OD1 no hydrogen 2.948 N/A TYR 181.A OH GLU 219.A O no hydrogen 2.838 N/A TRP 182.A N THR 179.A O no hydrogen 2.913 N/A TRP 182.A NE1 GLU 208.A OE1 no hydrogen 2.787 N/A MET 183.A N PRO 180.A O no hydrogen 3.183 N/A GLU 186.A N GLU 186.A OE1 no hydrogen 2.914 N/A ILE 188.A N ALA 184.A O no hydrogen 2.976 N/A SER 189.A N PRO 185.A O no hydrogen 2.677 N/A SER 189.A OG PRO 185.A O no hydrogen 3.048 N/A ARG 190.A N LEU 187.A O no hydrogen 3.101 N/A ARG 190.A NH1 LYS 174.A O no hydrogen 2.867 N/A LEU 191.A N GLU 186.A O no hydrogen 2.944 N/A TYR 193.A N ARG 173.A O no hydrogen 2.952 N/A TYR 193.A OH GLU 175.A O no hydrogen 2.569 N/A GLU 196.A N GLU 196.A OE1 no hydrogen 2.865 N/A VAL 197.A N GLY 194.A O no hydrogen 3.187 N/A ASP 198.A N PRO 195.A O no hydrogen 2.989 N/A ILE 199.A N GLU 196.A O no hydrogen 2.941 N/A TRP 200.A N GLU 196.A O no hydrogen 3.235 N/A SER 201.A N VAL 197.A O no hydrogen 3.048 N/A SER 201.A OG TRP 182.A O no hydrogen 2.712 N/A SER 201.A OG VAL 197.A O no hydrogen 3.095 N/A LEU 202.A N ASP 198.A O no hydrogen 2.900 N/A GLY 203.A N ILE 199.A O no hydrogen 3.113 N/A ILE 204.A N TRP 200.A O no hydrogen 3.086 N/A MET 205.A N SER 201.A O no hydrogen 2.969 N/A VAL 206.A N LEU 202.A O no hydrogen 2.828 N/A ILE 207.A N GLY 203.A O no hydrogen 2.900 N/A GLU 208.A N ILE 204.A O no hydrogen 2.859 N/A MET 209.A N MET 205.A O no hydrogen 2.786 N/A VAL 210.A N VAL 206.A O no hydrogen 2.951 N/A VAL 210.A N ILE 207.A O no hydrogen 3.180 N/A ASP 211.A N ILE 207.A O no hydrogen 2.789 N/A GLY 212.A N GLU 208.A O no hydrogen 2.856 N/A GLU 219.A N TYR 216.A O no hydrogen 2.905 N/A ALA 224.A N PRO 220.A O no hydrogen 2.838 N/A MET 225.A N PRO 221.A O no hydrogen 2.774 N/A LYS 226.A N LEU 222.A O no hydrogen 2.994 N/A MET 227.A N LYS 223.A O no hydrogen 3.005 N/A ILE 228.A N ALA 224.A O no hydrogen 2.894 N/A ARG 229.A N MET 225.A O no hydrogen 2.915 N/A ARG 229.A NE ASP 230.A OD1 no hydrogen 2.929 N/A ARG 229.A NH2 ASP 230.A OD1 no hydrogen 3.311 N/A ARG 229.A NH2 ASP 230.A OD2 no hydrogen 2.958 N/A ASP 230.A N LYS 226.A O no hydrogen 2.855 N/A ASN 231.A N MET 227.A O no hydrogen 2.853 N/A LYS 237.A N ASP 211.A OD2 no hydrogen 2.925 N/A ASN 238.A N ASP 211.A OD1 no hydrogen 3.352 N/A LYS 241.A N ASN 238.A O no hydrogen 2.851 N/A VAL 242.A N LEU 239.A O no hydrogen 3.241 N/A SER 243.A N GLU 115.A OE2 no hydrogen 2.891 N/A SER 243.A OG GLU 115.A OE1 no hydrogen 2.637 N/A SER 243.A OG GLU 115.A OE2 no hydrogen 3.438 N/A LEU 246.A N SER 243.A OG no hydrogen 3.012 N/A LYS 247.A N SER 243.A O no hydrogen 3.054 N/A LYS 247.A NZ ASP 251.A OD1 no hydrogen 3.025 N/A GLY 248.A N PRO 244.A O no hydrogen 2.894 N/A PHE 249.A N SER 245.A O no hydrogen 3.116 N/A LEU 250.A N LEU 246.A O no hydrogen 2.926 N/A ASP 251.A N LYS 247.A O no hydrogen 2.950 N/A ARG 252.A N GLY 248.A O no hydrogen 3.352 N/A ARG 252.A N PHE 249.A O no hydrogen 2.942 N/A ARG 252.A NH1 GLN 260.A O no hydrogen 3.049 N/A ARG 252.A NH2 GLN 260.A O no hydrogen 3.407 N/A LEU 253.A N LEU 250.A O no hydrogen 3.098 N/A LEU 254.A N LEU 250.A O no hydrogen 2.995 N/A ARG 256.A NH1 ILE 228.A O no hydrogen 2.967 N/A ARG 256.A NH1 ARG 229.A O no hydrogen 2.932 N/A ARG 256.A NH2 ARG 229.A O no hydrogen 2.528 N/A ALA 259.A N ASP 257.A OD1 no hydrogen 2.978 N/A GLN 260.A N ASP 257.A O no hydrogen 2.960 N/A ARG 261.A N PRO 258.A O no hydrogen 3.272 N/A ARG 261.A NE VAL 255.A O no hydrogen 2.732 N/A ARG 261.A NH1 GLU 186.A OE1 no hydrogen 3.561 N/A ARG 261.A NH1 GLU 186.A OE2 no hydrogen 2.856 N/A ARG 261.A NH1 GLU 196.A O no hydrogen 2.897 N/A ARG 261.A NH2 GLU 186.A OE1 no hydrogen 2.738 N/A ARG 261.A NH2 GLU 186.A OE2 no hydrogen 3.539 N/A ARG 261.A NH2 VAL 255.A O no hydrogen 2.816 N/A ALA 262.A N ARG 252.A O no hydrogen 2.951 N/A THR 263.A N GLU 266.A OE1 no hydrogen 3.129 N/A GLU 266.A N THR 263.A OG1 no hydrogen 3.129 N/A LEU 267.A N THR 263.A O no hydrogen 2.985 N/A LEU 268.A N ALA 264.A O no hydrogen 3.078 N/A LYS 269.A N GLU 266.A O no hydrogen 2.984 N/A HIS 270.A N LEU 267.A O no hydrogen 2.914 N/A PHE 272.A N HIS 270.A ND1 no hydrogen 3.078 N/A LEU 273.A N HIS 270.A O no hydrogen 2.997 N/A ALA 274.A N PRO 271.A O no hydrogen 2.853 N/A LYS 275.A N PHE 272.A O no hydrogen 3.107 N/A LYS 275.A NZ GLU 115.A OE1 no hydrogen 3.287 N/A ALA 276.A N LEU 273.A O no hydrogen 3.034 N/A GLY 277.A N GLU 116.A O no hydrogen 3.123 N/A SER 281.A N PRO 278.A O no hydrogen 3.004 N/A SER 281.A OG PRO 278.A O no hydrogen 2.662 N/A ILE 282.A N PRO 279.A O no hydrogen 2.851 N/A VAL 283.A N ALA 280.A O no hydrogen 3.240 N/A LEU 285.A N ILE 282.A O no hydrogen 2.919 N/A MET 286.A N VAL 283.A O no hydrogen 3.266 N/A ARG 287.A NH2 ASP 106.A OD1 no hydrogen 2.700 N/A GLN 288.A N GLN 288.A OE1 no hydrogen 2.861 N/A ASN 289.A N MET 286.A O no hydrogen 2.876 N/A ASN 289.A ND2 VAL 283.A O no hydrogen 3.022 N/A ARG 290.A N ARG 287.A O no hydrogen 3.400 N/A ARG 290.A NH1 ASP 106.A OD2 no hydrogen 3.342 N/A ARG 290.A NH1 LEU 285.A O no hydrogen 2.781 N/A ARG 290.A NH2 ASP 106.A OD2 no hydrogen 3.284 N/A