Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7siu_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 3.A N ASN 1.A OD1 no hydrogen 2.891 N/A PHE 4.A N ASN 1.A O no hydrogen 3.335 N/A PHE 10.A N SER 81.A O no hydrogen 2.927 N/A ARG 15.A N ASP 13.A OD1 no hydrogen 3.105 N/A ARG 15.A NH1 ASP 13.A OD1 no hydrogen 2.910 N/A ARG 15.A NH1 ASP 13.A OD2 no hydrogen 3.530 N/A ASP 16.A N ASP 13.A O no hydrogen 2.965 N/A HIS 17.A N PRO 14.A O no hydrogen 3.007 N/A HIS 17.A ND1 TYR 82.A OH no hydrogen 2.860 N/A TYR 18.A N PRO 14.A O no hydrogen 2.898 N/A ASP 19.A N ARG 36.A O no hydrogen 2.912 N/A LEU 21.A N LYS 34.A O no hydrogen 2.805 N/A ARG 23.A NE GLU 31.A OE2 no hydrogen 3.048 N/A LEU 24.A N VAL 32.A O no hydrogen 2.775 N/A GLY 25.A N VAL 32.A O no hydrogen 3.407 N/A GLY 27.A N GLY 30.A O no hydrogen 2.993 N/A GLY 30.A N GLY 27.A O no hydrogen 3.183 N/A GLU 31.A N MET 48.A O no hydrogen 3.096 N/A VAL 32.A N GLY 25.A O no hydrogen 2.957 N/A PHE 33.A N LEU 46.A O no hydrogen 2.808 N/A LYS 34.A N GLN 22.A O no hydrogen 2.879 N/A ALA 35.A N VAL 44.A O no hydrogen 2.862 N/A ARG 36.A N ASP 19.A O no hydrogen 3.049 N/A ARG 36.A NH1 GLY 41.A O no hydrogen 3.267 N/A ASP 37.A N ASP 42.A O no hydrogen 2.851 N/A LYS 38.A N HIS 17.A O no hydrogen 3.018 N/A LYS 38.A NZ ARG 15.A O no hydrogen 2.789 N/A VAL 39.A N ASP 37.A OD1 no hydrogen 2.943 N/A SER 40.A N ASP 37.A OD1 no hydrogen 3.287 N/A GLY 41.A N ASP 37.A O no hydrogen 2.976 N/A ASP 42.A N SER 40.A OG no hydrogen 3.361 N/A VAL 44.A N ALA 35.A O no hydrogen 2.863 N/A ALA 45.A N MET 92.A O no hydrogen 2.875 N/A LEU 46.A N PHE 33.A O no hydrogen 2.803 N/A LYS 47.A N ILE 90.A O no hydrogen 2.840 N/A MET 48.A N GLU 31.A O no hydrogen 2.767 N/A VAL 49.A N LEU 88.A O no hydrogen 2.802 N/A MET 51.A N GLN 86.A O no hydrogen 2.894 N/A GLU 52.A N ASP 55.A OD2 no hydrogen 2.827 N/A ASP 55.A N GLU 52.A O no hydrogen 3.144 N/A THR 59.A N ASP 56.A OD2 no hydrogen 2.933 N/A THR 59.A OG1 ASP 56.A OD1 no hydrogen 2.864 N/A THR 59.A OG1 ASP 56.A OD2 no hydrogen 2.732 N/A LEU 60.A N ASP 56.A O no hydrogen 3.141 N/A GLN 61.A N VAL 57.A O no hydrogen 2.944 N/A GLN 61.A NE2 VAL 57.A O no hydrogen 3.292 N/A LYS 62.A N SER 58.A O no hydrogen 3.246 N/A GLU 63.A N THR 59.A O no hydrogen 2.983 N/A ILE 64.A N LEU 60.A O no hydrogen 2.947 N/A LEU 65.A N GLN 61.A O no hydrogen 3.003 N/A ILE 66.A N LYS 62.A O no hydrogen 3.365 N/A ILE 66.A N GLU 63.A O no hydrogen 3.206 N/A LEU 67.A N GLU 63.A O no hydrogen 3.365 N/A LYS 68.A N ILE 64.A O no hydrogen 2.998 N/A LYS 68.A NZ ASP 6.A O no hydrogen 3.509 N/A LYS 68.A NZ PRO 7.A O no hydrogen 3.509 N/A THR 69.A N LEU 65.A O no hydrogen 3.186 N/A THR 69.A N ILE 66.A O no hydrogen 3.342 N/A THR 69.A OG1 LEU 65.A O no hydrogen 3.041 N/A THR 69.A OG1 ILE 66.A O no hydrogen 3.465 N/A ARG 71.A N TYR 128.A OH no hydrogen 2.986 N/A ARG 71.A NE LYS 68.A O no hydrogen 2.831 N/A ASN 74.A N HIS 72.A ND1 no hydrogen 2.930 N/A ASN 74.A ND2 GLU 121.A OE2 no hydrogen 2.957 N/A ASN 74.A ND2 VAL 152.A O no hydrogen 3.066 N/A ILE 75.A N HIS 72.A O no hydrogen 2.963 N/A VAL 76.A N LEU 154.A O no hydrogen 2.968 N/A ALA 77.A N GLU 93.A OE2 no hydrogen 2.944 N/A TYR 78.A OH SER 81.A OG no hydrogen 2.587 N/A HIS 79.A N CYS 91.A O no hydrogen 2.831 N/A GLY 80.A N CYS 91.A O no hydrogen 3.403 N/A SER 81.A OG TYR 78.A OH no hydrogen 2.587 N/A TYR 82.A N TRP 89.A O no hydrogen 2.930 N/A TYR 82.A OH HIS 17.A ND1 no hydrogen 2.860 N/A LEU 83.A N PHE 10.A O no hydrogen 2.892 N/A TRP 84.A N LYS 87.A O no hydrogen 2.935 N/A LYS 87.A N TRP 84.A O no hydrogen 3.090 N/A LEU 88.A N VAL 49.A O no hydrogen 2.869 N/A TRP 89.A N TYR 82.A O no hydrogen 2.761 N/A ILE 90.A N LYS 47.A O no hydrogen 2.824 N/A CYS 91.A N GLY 80.A O no hydrogen 2.826 N/A CYS 91.A SG TYR 18.A OH no hydrogen 3.450 N/A MET 92.A N ALA 45.A O no hydrogen 2.901 N/A GLU 93.A N ALA 77.A O no hydrogen 2.899 N/A ALA 97.A N ILE 146.A O no hydrogen 3.048 N/A GLY 98.A N CYS 95.A O no hydrogen 3.214 N/A SER 99.A N ASP 102.A OD2 no hydrogen 3.015 N/A LEU 100.A N ILE 144.A O no hydrogen 2.915 N/A GLN 101.A N GLY 141.A O no hydrogen 3.373 N/A ASP 102.A N SER 99.A OG no hydrogen 3.044 N/A ILE 103.A N SER 99.A O no hydrogen 3.038 N/A TYR 104.A N LEU 100.A O no hydrogen 2.808 N/A TYR 104.A OH GLU 208.A OE2 no hydrogen 2.567 N/A GLN 105.A N GLN 101.A O no hydrogen 3.104 N/A VAL 106.A N ILE 103.A O no hydrogen 2.915 N/A THR 107.A N ILE 103.A O no hydrogen 2.962 N/A THR 107.A OG1 ILE 103.A O no hydrogen 3.316 N/A THR 107.A OG1 GLY 108.A O no hydrogen 2.990 N/A GLY 108.A N TYR 104.A O no hydrogen 2.912 N/A LEU 110.A N LEU 209.A O no hydrogen 3.020 N/A SER 111.A N GLN 114.A OE1 no hydrogen 2.914 N/A GLN 114.A N SER 111.A OG no hydrogen 3.036 N/A GLN 114.A NE2 LEU 284.A O no hydrogen 3.037 N/A ILE 115.A N SER 111.A O no hydrogen 2.934 N/A SER 116.A N GLU 112.A O no hydrogen 2.883 N/A SER 116.A OG GLU 112.A O no hydrogen 2.701 N/A TYR 117.A N LEU 113.A O no hydrogen 3.085 N/A VAL 118.A N GLN 114.A O no hydrogen 3.048 N/A CYS 119.A N ILE 115.A O no hydrogen 2.862 N/A CYS 119.A SG ILE 115.A O no hydrogen 3.385 N/A ARG 120.A N SER 116.A O no hydrogen 2.949 N/A ARG 120.A NE GLU 121.A OE1 no hydrogen 2.981 N/A ARG 120.A NH1 LEU 280.A O no hydrogen 3.068 N/A ARG 120.A NH2 GLU 121.A OE1 no hydrogen 2.983 N/A GLU 121.A N TYR 117.A O no hydrogen 3.020 N/A VAL 122.A N VAL 118.A O no hydrogen 2.878 N/A LEU 123.A N CYS 119.A O no hydrogen 2.865 N/A GLN 124.A N ARG 120.A O no hydrogen 3.015 N/A GLN 124.A NE2 ASN 74.A OD1 no hydrogen 2.986 N/A GLN 124.A NE2 GLU 121.A OE1 no hydrogen 3.021 N/A GLY 125.A N GLU 121.A O no hydrogen 3.207 N/A LEU 126.A N VAL 122.A O no hydrogen 2.859 N/A ALA 127.A N LEU 123.A O no hydrogen 2.782 N/A TYR 128.A N GLN 124.A O no hydrogen 3.165 N/A LEU 129.A N GLY 125.A O no hydrogen 2.936 N/A HIS 130.A N LEU 126.A O no hydrogen 2.795 N/A HIS 130.A NE2 ASP 198.A OD2 no hydrogen 2.734 N/A SER 131.A N ALA 127.A O no hydrogen 3.037 N/A SER 131.A OG TYR 128.A O no hydrogen 2.583 N/A GLN 132.A N TYR 128.A O no hydrogen 3.182 N/A GLN 132.A N LEU 129.A O no hydrogen 3.043 N/A LYS 133.A N HIS 130.A O no hydrogen 3.051 N/A LYS 134.A N LEU 129.A O no hydrogen 3.013 N/A HIS 136.A N ASP 198.A OD2 no hydrogen 2.941 N/A HIS 136.A NE2 ASP 156.A O no hydrogen 3.132 N/A ARG 137.A N ASP 198.A OD1 no hydrogen 2.820 N/A ASP 138.A N HIS 136.A ND1 no hydrogen 2.982 N/A GLY 141.A N GLU 208.A OE1 no hydrogen 2.886 N/A ASN 143.A N LYS 140.A O no hydrogen 2.953 N/A ASN 143.A ND2 ASP 138.A O no hydrogen 2.835 N/A ILE 144.A N GLY 141.A O no hydrogen 3.391 N/A LEU 145.A N ARG 153.A O no hydrogen 2.746 N/A ILE 146.A N GLY 98.A O no hydrogen 2.915 N/A ASN 147.A N GLU 151.A O no hydrogen 3.084 N/A ASN 147.A ND2 GLU 151.A OE2 no hydrogen 3.094 N/A ALA 149.A N ASN 147.A OD1 no hydrogen 2.989 N/A GLY 150.A N ASN 147.A O no hydrogen 2.968 N/A GLU 151.A N ASN 147.A OD1 no hydrogen 2.956 N/A ARG 153.A N LEU 145.A O no hydrogen 2.880 N/A ARG 153.A NE GLU 93.A OE1 no hydrogen 2.853 N/A ARG 153.A NH1 VAL 152.A O no hydrogen 2.994 N/A LEU 154.A N ASN 74.A O no hydrogen 2.846 N/A ALA 155.A N ASN 143.A O no hydrogen 2.947 N/A GLY 158.A N ASP 156.A OD1 no hydrogen 2.857 N/A ILE 159.A N HIS 136.A O no hydrogen 2.949 N/A ALA 161.A N GLY 158.A O no hydrogen 2.907 N/A GLN 162.A N ILE 159.A O no hydrogen 3.220 N/A THR 166.A OG1 ILE 163.A O no hydrogen 3.192 N/A ALA 168.A N GLY 164.A O no hydrogen 2.970 N/A ARG 169.A N ALA 165.A O no hydrogen 3.018 N/A ARG 170.A N THR 166.A O no hydrogen 3.100 N/A ARG 170.A NE GLN 162.A OE1 no hydrogen 2.892 N/A ARG 170.A NH1 ALA 188.A O no hydrogen 2.716 N/A ARG 170.A NH2 LEU 189.A O no hydrogen 3.047 N/A LEU 171.A N LEU 167.A O no hydrogen 2.886 N/A SER 172.A N ALA 168.A O no hydrogen 3.079 N/A SER 172.A OG ALA 168.A O no hydrogen 3.317 N/A PHE 173.A N ARG 169.A O no hydrogen 3.153 N/A ILE 174.A N ARG 170.A O no hydrogen 2.962 N/A GLY 175.A N LEU 171.A O no hydrogen 2.932 N/A MET 180.A N PRO 177.A O no hydrogen 3.028 N/A GLU 183.A N GLU 183.A OE1 no hydrogen 2.842 N/A VAL 184.A N ALA 181.A O no hydrogen 2.993 N/A ALA 185.A N ALA 181.A O no hydrogen 2.940 N/A ALA 186.A N PRO 182.A O no hydrogen 2.929 N/A VAL 187.A N GLU 183.A O no hydrogen 3.393 N/A ALA 188.A N VAL 184.A O no hydrogen 2.948 N/A LEU 189.A N ALA 185.A O no hydrogen 2.903 N/A LYS 190.A N ALA 186.A O no hydrogen 3.036 N/A LYS 190.A NZ LYS 133.A O no hydrogen 3.285 N/A GLY 191.A N VAL 187.A O no hydrogen 2.997 N/A GLY 191.A N ALA 188.A O no hydrogen 3.255 N/A GLY 192.A N VAL 187.A O no hydrogen 3.082 N/A GLU 195.A N GLU 195.A OE2 no hydrogen 2.771 N/A LEU 196.A N ASN 194.A OD1 no hydrogen 3.054 N/A CYS 197.A N ASN 194.A O no hydrogen 3.443 N/A CYS 197.A SG ASN 194.A O no hydrogen 3.396 N/A ASP 198.A N GLU 195.A O no hydrogen 3.086 N/A ILE 199.A N LEU 196.A O no hydrogen 3.054 N/A TRP 200.A N LEU 196.A O no hydrogen 3.385 N/A SER 201.A N CYS 197.A O no hydrogen 3.047 N/A SER 201.A OG CYS 197.A O no hydrogen 3.206 N/A LEU 202.A N ASP 198.A O no hydrogen 3.004 N/A GLY 203.A N ILE 199.A O no hydrogen 3.167 N/A ILE 204.A N TRP 200.A O no hydrogen 3.025 N/A THR 205.A N SER 201.A O no hydrogen 2.894 N/A THR 205.A OG1 SER 201.A O no hydrogen 2.761 N/A ALA 206.A N LEU 202.A O no hydrogen 2.893 N/A ILE 207.A N GLY 203.A O no hydrogen 3.215 N/A GLU 208.A N ILE 204.A O no hydrogen 2.867 N/A LEU 209.A N THR 205.A O no hydrogen 2.869 N/A ALA 210.A N ALA 206.A O no hydrogen 3.094 N/A GLU 211.A N ILE 207.A O no hydrogen 2.782 N/A LEU 212.A N GLU 208.A O no hydrogen 2.750 N/A PHE 217.A N PRO 214.A O no hydrogen 3.276 N/A VAL 219.A N LEU 216.A O no hydrogen 2.903 N/A LEU 222.A N HIS 220.A ND1 no hydrogen 2.978 N/A ARG 223.A N HIS 220.A O no hydrogen 3.010 N/A VAL 224.A N HIS 220.A O no hydrogen 3.197 N/A LEU 225.A N PRO 221.A O no hydrogen 3.190 N/A PHE 226.A N LEU 222.A O no hydrogen 3.049 N/A LEU 227.A N ARG 223.A O no hydrogen 2.947 N/A MET 228.A N VAL 224.A O no hydrogen 3.345 N/A MET 228.A N LEU 225.A O no hydrogen 3.154 N/A THR 229.A N PHE 226.A O no hydrogen 2.914 N/A THR 229.A OG1 PHE 226.A O no hydrogen 2.643 N/A LYS 230.A N LEU 227.A O no hydrogen 3.378 N/A TYR 233.A N LYS 230.A O no hydrogen 3.136 N/A GLN 234.A NE2 TYR 233.A O no hydrogen 3.155 N/A LYS 239.A N GLU 211.A OE2 no hydrogen 2.775 N/A TRP 244.A N LYS 241.A O no hydrogen 3.282 N/A SER 245.A N GLU 112.A OE2 no hydrogen 2.871 N/A SER 245.A OG GLU 112.A OE1 no hydrogen 2.527 N/A SER 245.A OG GLU 112.A OE2 no hydrogen 3.490 N/A PHE 248.A N SER 245.A OG no hydrogen 3.135 N/A HIS 249.A N SER 245.A O no hydrogen 3.049 N/A HIS 249.A NE2 LYS 241.A O no hydrogen 2.838 N/A ASN 250.A N ALA 246.A O no hydrogen 2.915 N/A PHE 251.A N ALA 247.A O no hydrogen 2.902 N/A ILE 252.A N PHE 248.A O no hydrogen 3.080 N/A LYS 253.A N HIS 249.A O no hydrogen 2.961 N/A VAL 254.A N ASN 250.A O no hydrogen 2.930 N/A THR 255.A N PHE 251.A O no hydrogen 3.040 N/A THR 255.A OG1 PHE 251.A O no hydrogen 2.828 N/A THR 255.A OG1 ILE 252.A O no hydrogen 3.310 N/A LEU 256.A N ILE 252.A O no hydrogen 2.922 N/A THR 257.A OG1 LYS 253.A O no hydrogen 3.544 N/A THR 257.A OG1 VAL 254.A O no hydrogen 2.587 N/A ALA 262.A N SER 259.A O no hydrogen 3.019 N/A ARG 263.A N PRO 260.A O no hydrogen 3.056 N/A ARG 263.A NE THR 257.A O no hydrogen 2.849 N/A ARG 263.A NH1 LEU 196.A O no hydrogen 2.983 N/A ARG 263.A NH2 THR 257.A O no hydrogen 2.872 N/A LYS 268.A N SER 265.A OG no hydrogen 3.074 N/A MET 269.A N SER 265.A O no hydrogen 2.913 N/A LEU 270.A N ALA 266.A O no hydrogen 3.039 N/A SER 271.A N LYS 268.A O no hydrogen 2.927 N/A SER 271.A OG LYS 268.A O no hydrogen 2.584 N/A HIS 272.A N MET 269.A O no hydrogen 2.950 N/A HIS 272.A NE2 ASN 250.A OD1 no hydrogen 2.780 N/A LEU 274.A N HIS 272.A ND1 no hydrogen 3.075 N/A VAL 275.A N HIS 272.A O no hydrogen 3.083 N/A SER 276.A N HIS 272.A O no hydrogen 2.983 N/A SER 276.A OG HIS 272.A O no hydrogen 3.166 N/A GLN 277.A N GLN 273.A O no hydrogen 3.152 N/A GLN 277.A NE2 LEU 274.A O no hydrogen 2.823 N/A ARG 282.A NH1 ALA 149.A O no hydrogen 3.078 N/A GLY 283.A N ASN 281.A OD1 no hydrogen 3.011 N/A LEU 284.A N ASN 281.A O no hydrogen 3.078 N/A LEU 286.A N ARG 282.A O no hydrogen 2.917 N/A ASP 287.A N GLY 283.A O no hydrogen 3.130 N/A LEU 288.A N LEU 284.A O no hydrogen 3.358 N/A LEU 289.A N ILE 285.A O no hydrogen 2.852 N/A ASP 290.A N LEU 286.A O no hydrogen 2.912 N/A LYS 291.A N ASP 287.A O no hydrogen 3.103 N/A LYS 291.A NZ THR 107.A O no hydrogen 3.008 N/A LEU 292.A N LEU 288.A O no hydrogen 3.240 N/A LYS 293.A N LEU 289.A O no hydrogen 3.321 N/A LYS 293.A N ASP 290.A O no hydrogen 3.235 N/A ASN 294.A N ASP 290.A O no hydrogen 2.896 N/A ASN 294.A ND2 ASP 290.A O no hydrogen 3.082 N/A