Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7smk_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 9.A NZ SER 5.A O no hydrogen 3.030 N/A LYS 9.A NZ SER 5.A OG no hydrogen 3.322 N/A LYS 9.A NZ THR 59.A OG1 no hydrogen 2.860 N/A GLU 10.A N GLN 13.A OE1 no hydrogen 3.012 N/A TYR 11.A N GLU 43.A OE2 no hydrogen 3.052 N/A TYR 11.A OH GLU 51.A OE2 no hydrogen 2.744 N/A ARG 12.A N GLU 43.A OE1 no hydrogen 2.916 N/A THR 14.A N TYR 11.A O no hydrogen 3.149 N/A TYR 15.A N TYR 11.A O no hydrogen 2.975 N/A MET 17.A N ALA 75.A O no hydrogen 2.786 N/A GLU 19.A N GLU 19.A OE1 no hydrogen 2.754 N/A TYR 20.A N MET 17.A O no hydrogen 3.071 N/A TYR 20.A OH ASP 26.A OD2 no hydrogen 2.555 N/A LEU 23.A N ASP 26.A OD2 no hydrogen 2.884 N/A ASP 26.A N LEU 23.A O no hydrogen 3.244 N/A ILE 27.A N TYR 94.A O no hydrogen 2.898 N/A LEU 28.A N ARG 130.A O no hydrogen 3.238 N/A ALA 29.A N ILE 92.A O no hydrogen 2.861 N/A CYS 30.A N ASP 128.A O no hydrogen 2.834 N/A PHE 31.A N ALA 90.A O no hydrogen 2.965 N/A LYS 32.A N ARG 125.A O no hydrogen 2.660 N/A LYS 32.A NZ PRO 296.A O no hydrogen 3.003 N/A ILE 33.A N PHE 88.A O no hydrogen 2.801 N/A THR 34.A N GLY 123.A O no hydrogen 3.013 N/A GLN 36.A N ALA 120.A O no hydrogen 2.837 N/A GLN 36.A NE2 LYS 119.A O no hydrogen 3.541 N/A VAL 39.A N GLN 36.A O no hydrogen 3.276 N/A ARG 41.A NH1 ASP 80.A OD1 no hydrogen 2.898 N/A GLU 42.A N ASP 40.A OD1 no hydrogen 3.047 N/A GLU 42.A N GLU 42.A OE1 no hydrogen 2.834 N/A ALA 44.A N ASP 40.A O no hydrogen 2.857 N/A ALA 45.A N ARG 41.A O no hydrogen 2.797 N/A ALA 46.A N GLU 42.A O no hydrogen 2.750 N/A ALA 47.A N GLU 43.A O no hydrogen 2.808 N/A VAL 48.A N ALA 44.A O no hydrogen 3.046 N/A ALA 49.A N ALA 45.A O no hydrogen 2.929 N/A ALA 50.A N ALA 46.A O no hydrogen 2.769 N/A GLU 51.A N ALA 47.A O no hydrogen 3.054 N/A SER 52.A N VAL 48.A O no hydrogen 3.096 N/A SER 52.A OG VAL 48.A O no hydrogen 2.600 N/A SER 52.A OG ALA 49.A O no hydrogen 3.118 N/A SER 52.A OG TYR 94.A OH no hydrogen 2.647 N/A SER 53.A N ALA 50.A O no hydrogen 3.187 N/A SER 53.A OG ALA 49.A O no hydrogen 2.669 N/A SER 53.A OG ALA 50.A O no hydrogen 3.525 N/A THR 54.A N SER 53.A OG no hydrogen 2.590 N/A GLY 55.A N ALA 50.A O no hydrogen 2.604 N/A THR 59.A N GLY 7.A O no hydrogen 3.005 N/A THR 59.A OG1 GLY 7.A O no hydrogen 2.968 N/A ASP 63.A N VAL 60.A O no hydrogen 3.405 N/A LEU 64.A N TRP 61.A O no hydrogen 2.907 N/A LEU 65.A N THR 62.A O no hydrogen 3.012 N/A THR 66.A N ASP 63.A O no hydrogen 3.224 N/A ASP 67.A N THR 66.A OG1 no hydrogen 2.786 N/A ASP 69.A N ASP 67.A OD1 no hydrogen 2.906 N/A TYR 70.A N ASP 67.A O no hydrogen 3.132 N/A TYR 70.A OH ASP 97.A OD2 no hydrogen 2.466 N/A TYR 71.A N ASP 67.A O no hydrogen 3.280 N/A LYS 72.A N MET 68.A O no hydrogen 2.853 N/A LYS 72.A NZ THR 14.A O no hydrogen 2.891 N/A LYS 72.A NZ ASP 69.A OD1 no hydrogen 3.532 N/A GLY 73.A N SER 53.A OG no hydrogen 3.120 N/A ARG 74.A N ALA 93.A O no hydrogen 3.017 N/A ARG 74.A NE LYS 72.A O no hydrogen 3.052 N/A ARG 74.A NH1 ASP 69.A O no hydrogen 3.287 N/A ARG 74.A NH2 ASP 69.A O no hydrogen 2.910 N/A ARG 74.A NH2 TYR 70.A O no hydrogen 3.079 N/A ARG 74.A NH2 LYS 72.A O no hydrogen 2.510 N/A ALA 75.A N TYR 15.A O no hydrogen 2.848 N/A TYR 76.A N PHE 91.A O no hydrogen 2.827 N/A ARG 77.A NE GLU 79.A OE2 no hydrogen 2.749 N/A GLU 79.A N TYR 89.A O no hydrogen 2.916 N/A ASP 84.A N VAL 81.A O no hydrogen 2.973 N/A ALA 86.A N ASP 84.A OD1 no hydrogen 3.176 N/A PHE 88.A N ILE 33.A O no hydrogen 2.965 N/A TYR 89.A N GLU 79.A O no hydrogen 2.733 N/A ALA 90.A N PHE 31.A O no hydrogen 2.774 N/A PHE 91.A N ARG 77.A O no hydrogen 2.941 N/A ILE 92.A N ALA 29.A O no hydrogen 2.957 N/A ALA 93.A N ARG 74.A O no hydrogen 2.857 N/A TYR 94.A N ILE 27.A O no hydrogen 2.650 N/A TYR 94.A OH SER 52.A OG no hydrogen 2.647 N/A LEU 98.A N PRO 95.A O no hydrogen 3.050 N/A PHE 99.A N ILE 96.A O no hydrogen 3.244 N/A GLU 100.A N ASN 106.A OD1 no hydrogen 2.952 N/A GLU 101.A N GLU 101.A OE1 no hydrogen 2.989 N/A GLY 102.A N THR 138.A OG1 no hydrogen 2.788 N/A SER 103.A N TYR 135.A OH no hydrogen 3.067 N/A ASN 106.A N SER 103.A OG no hydrogen 3.110 N/A VAL 107.A N SER 103.A O no hydrogen 3.302 N/A PHE 108.A N VAL 104.A O no hydrogen 2.866 N/A THR 109.A N VAL 105.A O no hydrogen 2.719 N/A THR 109.A OG1 VAL 105.A O no hydrogen 2.777 N/A SER 110.A N ASN 106.A O no hydrogen 3.002 N/A SER 110.A OG ASN 106.A O no hydrogen 3.046 N/A LEU 111.A N VAL 107.A O no hydrogen 3.121 N/A VAL 112.A N PHE 108.A O no hydrogen 2.989 N/A GLY 117.A N ASN 114.A O no hydrogen 3.223 N/A PHE 118.A N VAL 115.A O no hydrogen 3.300 N/A ARG 122.A N THR 34.A O no hydrogen 2.613 N/A GLY 123.A N THR 34.A O no hydrogen 3.212 N/A LEU 124.A N HIS 298.A ND1 no hydrogen 3.228 N/A ARG 125.A N LYS 32.A O no hydrogen 3.013 N/A ARG 125.A NH1 GLU 127.A OE2 no hydrogen 3.001 N/A ARG 125.A NH2 ASP 293.A O no hydrogen 3.229 N/A LEU 126.A N GLY 299.A O no hydrogen 2.978 N/A GLU 127.A N CYS 30.A O no hydrogen 2.703 N/A ASP 128.A N CYS 30.A O no hydrogen 3.465 N/A VAL 129.A N ASP 128.A OD1 no hydrogen 3.005 N/A ARG 130.A N LEU 28.A O no hydrogen 2.688 N/A ARG 130.A NE ASP 26.A O no hydrogen 3.023 N/A ARG 130.A NE ARG 130.A O no hydrogen 3.294 N/A ARG 130.A NH2 LEU 23.A O no hydrogen 3.094 N/A ARG 130.A NH2 ASP 26.A O no hydrogen 2.460 N/A PHE 131.A N GLN 357.A OE1 no hydrogen 3.148 N/A TYR 135.A OH GLU 100.A O no hydrogen 2.651 N/A TYR 135.A OH SER 103.A O no hydrogen 2.863 N/A VAL 136.A N PRO 132.A O no hydrogen 2.890 N/A LYS 137.A N LEU 133.A O no hydrogen 2.944 N/A THR 138.A N TYR 135.A O no hydrogen 2.989 N/A THR 138.A OG1 TYR 135.A O no hydrogen 2.742 N/A CYS 139.A N VAL 136.A O no hydrogen 2.995 N/A CYS 139.A SG TYR 135.A O no hydrogen 3.744 N/A GLY 141.A N LEU 311.A O no hydrogen 3.026 N/A HIS 144.A N ASP 315.A OD1 no hydrogen 2.805 N/A HIS 144.A ND1 ASP 315.A OD2 no hydrogen 2.944 N/A GLY 145.A N ASP 315.A OD1 no hydrogen 2.992 N/A ILE 146.A N GLY 364.A O no hydrogen 3.098 N/A GLU 149.A N GLY 145.A O no hydrogen 2.893 N/A ARG 150.A N ILE 146.A O no hydrogen 2.951 N/A ARG 150.A NE ASP 388.A OD1 no hydrogen 3.212 N/A ARG 150.A NH1 LYS 155.A O no hydrogen 2.933 N/A ARG 150.A NH1 ARG 158.A O no hydrogen 3.381 N/A ARG 150.A NH2 ARG 158.A O no hydrogen 2.984 N/A ARG 150.A NH2 ASP 388.A OD1 no hydrogen 3.454 N/A ASP 151.A N GLN 147.A O no hydrogen 3.030 N/A LYS 152.A N VAL 148.A O no hydrogen 2.822 N/A MET 153.A N GLU 149.A O no hydrogen 2.900 N/A ASN 154.A N ASP 151.A O no hydrogen 3.354 N/A LYS 155.A N ARG 150.A O no hydrogen 3.081 N/A LYS 155.A NZ ASP 189.A OD1 no hydrogen 3.034 N/A LYS 155.A NZ ARG 226.A O no hydrogen 2.723 N/A TYR 156.A OH ASP 151.A OD1 no hydrogen 2.645 N/A ARG 158.A NH1 PRO 159.A O no hydrogen 2.982 N/A ARG 158.A NH1 ASP 189.A OD2 no hydrogen 2.787 N/A ARG 158.A NH2 ASP 189.A OD1 no hydrogen 2.588 N/A ARG 158.A NH2 ASP 189.A OD2 no hydrogen 3.364 N/A LEU 160.A N SER 389.A O no hydrogen 2.872 N/A LEU 161.A N ASP 189.A OD2 no hydrogen 2.753 N/A GLY 162.A N LEU 391.A O no hydrogen 2.715 N/A CYS 163.A SG THR 164.A O no hydrogen 3.480 N/A CYS 163.A SG PHE 393.A O no hydrogen 3.170 N/A CYS 163.A SG GLY 394.A O no hydrogen 3.711 N/A ILE 165.A N LYS 192.A O no hydrogen 3.245 N/A LYS 166.A NZ ASP 194.A OD1 no hydrogen 3.450 N/A LYS 168.A NZ ASP 194.A OD2 no hydrogen 3.540 N/A LYS 168.A NZ ASN 196.A OD1 no hydrogen 2.351 N/A ASN 175.A N SER 172.A OG no hydrogen 3.335 N/A TYR 176.A N SER 172.A O no hydrogen 2.751 N/A TYR 176.A OH ASP 193.A OD1 no hydrogen 3.249 N/A GLY 177.A N ALA 173.A O no hydrogen 2.911 N/A ARG 178.A N LYS 174.A O no hydrogen 2.966 N/A ARG 178.A NH1 GLU 182.A OE2 no hydrogen 3.021 N/A ALA 179.A N ASN 175.A O no hydrogen 3.029 N/A VAL 180.A N TYR 176.A O no hydrogen 2.957 N/A TYR 181.A N GLY 177.A O no hydrogen 2.684 N/A TYR 181.A OH GLN 222.A OE1 no hydrogen 2.469 N/A GLU 182.A N ARG 178.A O no hydrogen 2.964 N/A CYS 183.A N ALA 179.A O no hydrogen 3.088 N/A CYS 183.A SG ALA 179.A O no hydrogen 3.172 N/A LEU 184.A N VAL 180.A O no hydrogen 2.955 N/A ARG 185.A N TYR 181.A O no hydrogen 2.967 N/A ARG 185.A NE GLU 182.A OE1 no hydrogen 2.907 N/A ARG 185.A NE GLU 182.A OE2 no hydrogen 3.468 N/A ARG 185.A NH2 GLU 182.A OE1 no hydrogen 3.131 N/A GLY 186.A N GLU 182.A O no hydrogen 3.249 N/A GLY 186.A N CYS 183.A O no hydrogen 3.262 N/A GLY 187.A N LEU 184.A O no hydrogen 3.221 N/A PHE 190.A N LEU 161.A O no hydrogen 2.937 N/A THR 191.A N GLY 228.A O no hydrogen 3.094 N/A THR 191.A OG1 HIS 229.A ND1 no hydrogen 2.556 N/A LYS 192.A N CYS 163.A O no hydrogen 2.784 N/A LYS 192.A NZ THR 164.A OG1 no hydrogen 3.321 N/A LYS 192.A NZ ASP 193.A O no hydrogen 2.878 N/A ASP 193.A N TYR 230.A O no hydrogen 3.093 N/A GLU 195.A N GLU 195.A OE1 no hydrogen 2.800 N/A ASN 196.A N ASP 194.A OD2 no hydrogen 3.000 N/A ILE 197.A N ASP 194.A O no hydrogen 3.029 N/A ASN 198.A N GLN 200.A OE1 no hydrogen 3.103 N/A ASN 198.A ND2 ILE 197.A O no hydrogen 2.868 N/A GLN 200.A N MET 203.A O no hydrogen 3.110 N/A GLN 200.A NE2 ASN 196.A O no hydrogen 2.775 N/A MET 203.A N GLN 200.A O no hydrogen 2.936 N/A TRP 205.A N SER 199.A OG no hydrogen 3.004 N/A ARG 208.A N ARG 204.A O no hydrogen 3.006 N/A ARG 208.A NE ASP 193.A OD2 no hydrogen 2.859 N/A ARG 208.A NH1 ASN 198.A O no hydrogen 2.738 N/A ARG 208.A NH2 ASP 193.A OD2 no hydrogen 3.205 N/A ARG 208.A NH2 ASN 198.A O no hydrogen 2.962 N/A PHE 209.A N TRP 205.A O no hydrogen 2.815 N/A LEU 210.A N ARG 206.A O no hydrogen 3.081 N/A PHE 211.A N ASP 207.A O no hydrogen 3.101 N/A VAL 212.A N ARG 208.A O no hydrogen 2.858 N/A GLN 213.A N PHE 209.A O no hydrogen 2.996 N/A GLN 213.A NE2 GLU 217.A OE2 no hydrogen 3.120 N/A ASP 214.A N LEU 210.A O no hydrogen 3.066 N/A ALA 215.A N PHE 211.A O no hydrogen 2.868 N/A THR 216.A N VAL 212.A O no hydrogen 2.739 N/A THR 216.A OG1 VAL 212.A O no hydrogen 2.926 N/A GLU 217.A N GLN 213.A O no hydrogen 2.974 N/A THR 218.A N ASP 214.A O no hydrogen 2.987 N/A THR 218.A OG1 ASP 214.A O no hydrogen 2.648 N/A ALA 219.A N ALA 215.A O no hydrogen 3.025 N/A GLU 220.A N THR 216.A O no hydrogen 2.954 N/A ALA 221.A N GLU 217.A O no hydrogen 3.025 N/A GLN 222.A N THR 218.A O no hydrogen 3.065 N/A THR 223.A OG1 ALA 219.A O no hydrogen 2.829 N/A THR 223.A OG1 GLU 220.A O no hydrogen 3.552 N/A THR 223.A OG1 GLU 225.A O no hydrogen 3.553 N/A GLY 224.A N GLU 220.A O no hydrogen 2.967 N/A GLU 225.A N THR 223.A OG1 no hydrogen 3.331 N/A LYS 227.A N GLU 220.A OE1 no hydrogen 3.148 N/A LYS 227.A NZ LEU 184.A O no hydrogen 3.004 N/A LYS 227.A NZ LEU 188.A O no hydrogen 2.749 N/A GLY 228.A N ASP 189.A O no hydrogen 3.155 N/A HIS 229.A ND1 THR 191.A OG1 no hydrogen 2.556 N/A HIS 229.A NE2 ASP 193.A OD1 no hydrogen 2.681 N/A TYR 230.A N THR 191.A O no hydrogen 2.823 N/A ASN 232.A N ASP 193.A OD2 no hydrogen 2.731 N/A ASN 232.A ND2 ASP 194.A O no hydrogen 3.361 N/A ASN 232.A ND2 GLU 195.A O no hydrogen 3.185 N/A ASN 232.A ND2 ILE 197.A O no hydrogen 3.023 N/A VAL 233.A N MET 257.A O no hydrogen 3.095 N/A THR 234.A N ASN 232.A OD1 no hydrogen 3.069 N/A THR 234.A OG1 ASN 232.A OD1 no hydrogen 2.627 N/A GLU 239.A N GLU 239.A OE1 no hydrogen 2.613 N/A GLU 240.A N THR 237.A OG1 no hydrogen 3.125 N/A MET 241.A N THR 237.A O no hydrogen 2.921 N/A TYR 242.A N PRO 238.A O no hydrogen 2.885 N/A LYS 243.A N GLU 239.A O no hydrogen 2.977 N/A ARG 244.A N GLU 240.A O no hydrogen 3.074 N/A ARG 244.A NE GLU 240.A OE2 no hydrogen 3.162 N/A ALA 245.A N MET 241.A O no hydrogen 3.040 N/A GLU 246.A N TYR 242.A O no hydrogen 2.799 N/A PHE 247.A N LYS 243.A O no hydrogen 3.009 N/A ALA 248.A N ARG 244.A O no hydrogen 2.993 N/A LYS 249.A N ALA 245.A O no hydrogen 3.019 N/A LYS 249.A NZ ASN 278.A O no hydrogen 3.489 N/A LYS 249.A NZ ASN 278.A OD1 no hydrogen 2.884 N/A GLU 250.A N GLU 246.A O no hydrogen 2.830 N/A ILE 251.A N PHE 247.A O no hydrogen 3.004 N/A GLY 252.A N LYS 249.A O no hydrogen 3.105 N/A ALA 253.A N ALA 248.A O no hydrogen 2.872 N/A ILE 256.A N LEU 281.A O no hydrogen 2.891 N/A MET 257.A N LEU 231.A O no hydrogen 2.844 N/A HIS 258.A N HIS 283.A O no hydrogen 2.927 N/A HIS 258.A ND1 ASN 268.A OD1 no hydrogen 2.970 N/A ASP 259.A N THR 234.A OG1 no hydrogen 3.242 N/A TYR 260.A N HIS 285.A O no hydrogen 3.389 N/A TYR 260.A OH LEU 305.A O no hydrogen 3.100 N/A GLY 263.A N ASP 259.A O no hydrogen 2.773 N/A GLY 264.A N TYR 260.A O no hydrogen 3.002 N/A ASN 268.A N GLY 264.A O no hydrogen 2.925 N/A ASN 268.A ND2 SER 312.A OG no hydrogen 2.936 N/A ASN 268.A ND2 GLY 313.A O no hydrogen 3.088 N/A THR 269.A N PHE 265.A O no hydrogen 2.824 N/A THR 269.A OG1 PHE 265.A O no hydrogen 2.763 N/A THR 269.A OG1 SER 312.A OG no hydrogen 2.985 N/A GLY 270.A N THR 266.A O no hydrogen 3.135 N/A LEU 271.A N ALA 267.A O no hydrogen 2.886 N/A ALA 272.A N ASN 268.A O no hydrogen 2.775 N/A LYS 273.A N THR 269.A O no hydrogen 3.039 N/A TRP 274.A N GLY 270.A O no hydrogen 2.889 N/A TRP 274.A NE1 GLU 246.A OE2 no hydrogen 2.863 N/A CYS 275.A N LEU 271.A O no hydrogen 2.734 N/A CYS 275.A SG LEU 271.A O no hydrogen 3.281 N/A GLN 276.A N ALA 272.A O no hydrogen 3.079 N/A ASP 277.A N LYS 273.A O no hydrogen 3.018 N/A ASN 278.A N TRP 274.A O no hydrogen 2.961 N/A ASN 278.A N CYS 275.A O no hydrogen 3.254 N/A ASN 278.A ND2 TRP 274.A O no hydrogen 2.822 N/A VAL 280.A N CYS 275.A O no hydrogen 3.107 N/A LEU 281.A N PRO 254.A O no hydrogen 2.961 N/A LEU 282.A N ASP 315.A OD2 no hydrogen 2.976 N/A HIS 283.A N ILE 256.A O no hydrogen 2.788 N/A ILE 284.A N HIS 316.A O no hydrogen 2.840 N/A HIS 285.A N HIS 258.A O no hydrogen 2.897 N/A ARG 286.A NE HIS 318.A ND1.A no hydrogen 3.016 N/A ALA 287.A N ASP 259.A OD1 no hydrogen 3.127 N/A HIS 289.A N ARG 286.A O no hydrogen 3.067 N/A HIS 289.A ND1 ASP 293.A OD2 no hydrogen 2.995 N/A VAL 291.A N MET 288.A O no hydrogen 2.965 N/A ILE 292.A N HIS 289.A O no hydrogen 2.946 N/A ASP 293.A N HIS 289.A O no hydrogen 2.647 N/A ARG 294.A N ALA 290.A O no hydrogen 3.426 N/A ASN 297.A N ASN 295.A OD1 no hydrogen 3.007 N/A ASN 297.A ND2 ASN 295.A OD1 no hydrogen 3.408 N/A GLY 299.A N LEU 124.A O no hydrogen 2.994 N/A ILE 300.A N ILE 292.A O no hydrogen 3.094 N/A HIS 301.A N LEU 126.A O no hydrogen 3.047 N/A ARG 303.A N HIS 301.A ND1 no hydrogen 2.963 N/A ARG 303.A NH1 GLU 127.A O no hydrogen 2.931 N/A ARG 303.A NH1 GLU 127.A OE1 no hydrogen 2.962 N/A VAL 304.A N HIS 301.A O no hydrogen 3.014 N/A LEU 305.A N HIS 301.A O no hydrogen 3.500 N/A THR 306.A N PHE 302.A O no hydrogen 2.683 N/A THR 306.A OG1 PHE 302.A O no hydrogen 2.917 N/A LYS 307.A N ARG 303.A O no hydrogen 3.109 N/A LYS 307.A NZ ASP 128.A OD1 no hydrogen 3.242 N/A LYS 307.A NZ VAL 129.A O no hydrogen 2.647 N/A LYS 307.A NZ GLN 357.A OE1 no hydrogen 2.874 N/A ILE 308.A N VAL 304.A O no hydrogen 3.059 N/A LEU 309.A N LEU 305.A O no hydrogen 3.023 N/A ARG 310.A N THR 306.A O no hydrogen 3.044 N/A ARG 310.A NE PRO 363.A O no hydrogen 3.037 N/A ARG 310.A NH1 LEU 339.A O no hydrogen 2.632 N/A ARG 310.A NH1 GLU 342.A O no hydrogen 2.684 N/A ARG 310.A NH2 GLU 342.A O no hydrogen 3.033 N/A ARG 310.A NH2 MET 362.A O no hydrogen 2.891 N/A ARG 310.A NH2 PRO 363.A O no hydrogen 3.230 N/A LEU 311.A N LYS 307.A O no hydrogen 3.032 N/A SER 312.A N ILE 308.A O no hydrogen 2.678 N/A SER 312.A OG THR 269.A OG1 no hydrogen 2.985 N/A GLY 313.A N LEU 309.A O no hydrogen 2.702 N/A ASP 315.A N LEU 282.A O no hydrogen 2.632 N/A HIS 316.A N LEU 282.A O no hydrogen 3.168 N/A HIS 316.A NE2 GLU 149.A OE1 no hydrogen 2.760 N/A HIS 316.A NE2 GLU 149.A OE2 no hydrogen 2.358 N/A LEU 317.A N PHE 366.A O no hydrogen 2.899 N/A HIS 318.A N ILE 284.A O no hydrogen 3.158 N/A HIS 318.A NE2.A SER 370.A OG no hydrogen 2.429 N/A THR 319.A N VAL 368.A O no hydrogen 2.755 N/A THR 319.A OG1 VAL 368.A O no hydrogen 2.820 N/A THR 321.A OG1 SER 370.A O no hydrogen 3.087 N/A LEU 326.A N ASP 329.A OD2 no hydrogen 2.483 N/A ARG 330.A N LEU 326.A O no hydrogen 2.618 N/A ARG 330.A N GLU 327.A O no hydrogen 3.195 N/A ALA 331.A N GLU 327.A O no hydrogen 3.472 N/A SER 332.A OG HIS 301.A NE2 no hydrogen 3.263 N/A THR 333.A N ASP 329.A O no hydrogen 2.995 N/A THR 333.A OG1 ASP 329.A O no hydrogen 2.877 N/A LEU 334.A N ARG 330.A O no hydrogen 2.836 N/A GLY 335.A N ALA 331.A O no hydrogen 2.859 N/A TRP 336.A N SER 332.A O no hydrogen 3.110 N/A ILE 337.A N THR 333.A O no hydrogen 3.068 N/A ASP 338.A N LEU 334.A O no hydrogen 3.141 N/A LEU 339.A N GLY 335.A O no hydrogen 3.103 N/A LEU 340.A N TRP 336.A O no hydrogen 2.771 N/A ARG 341.A N ILE 337.A O no hydrogen 2.994 N/A ARG 341.A N ASP 338.A O no hydrogen 3.200 N/A ARG 341.A NH1 PHE 385.A O no hydrogen 2.810 N/A ARG 341.A NH1 ASP 388.A O no hydrogen 2.882 N/A ARG 341.A NH2 PHE 385.A O no hydrogen 2.887 N/A GLU 342.A N ASP 338.A O no hydrogen 2.682 N/A SER 343.A OG GLY 360.A O no hydrogen 2.728 N/A ILE 345.A N GLN 357.A O no hydrogen 2.871 N/A GLU 347.A N ASP 356.A OD1 no hydrogen 2.445 N/A ASP 348.A N ILE 353.A O no hydrogen 2.879 N/A ARG 349.A NE GLU 347.A OE2 no hydrogen 2.834 N/A ARG 349.A NH1 GLU 79.A OE1 no hydrogen 3.032 N/A ARG 349.A NH2 GLU 79.A OE1 no hydrogen 3.261 N/A ARG 349.A NH2 GLU 79.A OE2 no hydrogen 3.381 N/A ARG 349.A NH2 GLU 347.A OE2 no hydrogen 3.421 N/A SER 350.A N ASP 348.A OD1 no hydrogen 3.320 N/A SER 350.A OG ASP 348.A OD1 no hydrogen 2.657 N/A SER 350.A OG ASP 348.A OD2 no hydrogen 3.306 N/A ARG 351.A N ASP 348.A O no hydrogen 3.123 N/A ARG 351.A NE ASP 348.A OD2 no hydrogen 3.363 N/A ARG 351.A NH1 ASP 338.A OD2 no hydrogen 2.954 N/A ARG 351.A NH2 ASP 338.A OD2 no hydrogen 2.791 N/A GLY 352.A N ARG 349.A O no hydrogen 3.063 N/A ILE 353.A N ASP 348.A O no hydrogen 2.837 N/A PHE 354.A N ASP 128.A OD2 no hydrogen 3.005 N/A GLN 357.A N ILE 345.A O no hydrogen 2.928 N/A GLN 357.A NE2 PHE 131.A O no hydrogen 3.019 N/A GLN 357.A NE2 ASP 358.A O no hydrogen 3.068 N/A TRP 359.A N SER 343.A O no hydrogen 2.689 N/A GLY 360.A N ASP 358.A OD1 no hydrogen 2.907 N/A MET 362.A N TRP 359.A O no hydrogen 3.125 N/A VAL 365.A N LEU 340.A O no hydrogen 3.008 N/A PHE 366.A N ASP 315.A O no hydrogen 2.890 N/A VAL 368.A N LEU 317.A O no hydrogen 2.924 N/A ALA 369.A N VAL 390.A O no hydrogen 2.842 N/A SER 370.A OG HIS 318.A NE2.A no hydrogen 2.429 N/A HIS 374.A N HIS 377.A ND1 no hydrogen 2.922 N/A TRP 376.A N HIS 374.A ND1 no hydrogen 3.357 N/A TRP 376.A NE1 MET 450.A O no hydrogen 3.115 N/A TRP 376.A NE1 TRP 453.A O no hydrogen 2.897 N/A HIS 377.A N HIS 374.A O no hydrogen 2.717 N/A MET 378.A N VAL 375.A O no hydrogen 2.986 N/A LEU 381.A N HIS 377.A O no hydrogen 2.941 N/A VAL 382.A N MET 378.A O no hydrogen 2.875 N/A ASN 383.A N PRO 379.A O no hydrogen 3.046 N/A ASN 383.A ND2 GLU 429.A OE2 no hydrogen 2.328 N/A ILE 384.A N ALA 380.A O no hydrogen 2.868 N/A PHE 385.A N LEU 381.A O no hydrogen 2.930 N/A GLY 386.A N VAL 382.A O no hydrogen 3.015 N/A SER 389.A N ASP 387.A O no hydrogen 2.668 N/A SER 389.A OG GLY 386.A O no hydrogen 3.118 N/A VAL 390.A N ALA 367.A O no hydrogen 2.808 N/A LEU 391.A N LEU 160.A O no hydrogen 2.853 N/A GLN 392.A N ALA 369.A O no hydrogen 2.821 N/A GLN 392.A NE2 HIS 318.A NE2.B no hydrogen 3.125 N/A PHE 393.A N GLY 162.A O no hydrogen 2.787 N/A THR 397.A N GLY 394.A O no hydrogen 3.154 N/A THR 397.A OG1 PHE 393.A O no hydrogen 2.673 N/A LEU 398.A N GLY 394.A O no hydrogen 3.071 N/A GLY 399.A N GLY 395.A O no hydrogen 2.849 N/A HIS 400.A N THR 397.A O no hydrogen 3.237 N/A HIS 400.A NE2 GLU 445.A O no hydrogen 2.974 N/A TRP 402.A N HIS 400.A ND1 no hydrogen 2.869 N/A GLY 403.A N HIS 400.A O no hydrogen 3.118 N/A ASN 404.A ND2 ALA 179.A O no hydrogen 3.117 N/A GLY 407.A N GLY 403.A O no hydrogen 2.911 N/A ALA 408.A N ASN 404.A O no hydrogen 2.775 N/A ALA 409.A N ALA 405.A O no hydrogen 3.000 N/A ALA 410.A N ALA 406.A O no hydrogen 2.815 N/A ASN 411.A N GLY 407.A O no hydrogen 3.041 N/A ASN 411.A ND2 GLY 396.A O no hydrogen 3.200 N/A ARG 412.A N ALA 408.A O no hydrogen 2.809 N/A ARG 412.A NE GLU 416.A OE2 no hydrogen 3.019 N/A ARG 412.A NH1 GLY 187.A O no hydrogen 2.814 N/A ARG 412.A NH1 GLU 225.A OE1 no hydrogen 3.100 N/A ARG 412.A NH2 GLU 225.A OE2 no hydrogen 3.018 N/A ARG 412.A NH2 GLU 416.A OE2 no hydrogen 3.224 N/A VAL 413.A N ALA 409.A O no hydrogen 2.797 N/A ALA 414.A N ALA 410.A O no hydrogen 2.978 N/A LEU 415.A N ASN 411.A O no hydrogen 2.864 N/A GLU 416.A N ARG 412.A O no hydrogen 2.956 N/A ALA 417.A N VAL 413.A O no hydrogen 2.863 N/A CYS 418.A N ALA 414.A O no hydrogen 3.026 N/A CYS 418.A SG ALA 414.A O no hydrogen 3.224 N/A VAL 419.A N LEU 415.A O no hydrogen 2.932 N/A GLU 420.A N GLU 416.A O no hydrogen 2.822 N/A ALA 421.A N ALA 417.A O no hydrogen 2.957 N/A ARG 422.A N CYS 418.A O no hydrogen 2.891 N/A ARG 422.A NE ASN 423.A OD1 no hydrogen 3.138 N/A ARG 422.A NH1 ASP 387.A OD1 no hydrogen 2.811 N/A ARG 422.A NH2 ASP 387.A OD1 no hydrogen 3.134 N/A ARG 422.A NH2 ASP 387.A OD2 no hydrogen 3.280 N/A ARG 422.A NH2 ASN 423.A OD1 no hydrogen 3.017 N/A ASN 423.A N VAL 419.A O no hydrogen 2.917 N/A GLN 424.A N GLU 420.A O no hydrogen 3.015 N/A GLY 425.A N ARG 422.A O no hydrogen 2.944 N/A ARG 426.A N ALA 421.A O no hydrogen 3.105 N/A ARG 426.A NE GLU 431.A OE2 no hydrogen 3.083 N/A ARG 426.A NH2 GLU 431.A OE2 no hydrogen 3.193 N/A ASP 427.A N GLU 431.A OE1 no hydrogen 2.918 N/A GLU 431.A N ASP 427.A O no hydrogen 2.849 N/A GLY 432.A N GLU 429.A O no hydrogen 3.440 N/A LYS 433.A NZ GLU 455.A OE1 no hydrogen 2.362 N/A GLU 434.A N GLU 434.A OE1 no hydrogen 2.879 N/A ILE 435.A N GLU 431.A O no hydrogen 2.898 N/A LEU 436.A N GLY 432.A O no hydrogen 2.871 N/A THR 437.A N LYS 433.A O no hydrogen 2.744 N/A THR 437.A OG1 LYS 433.A O no hydrogen 2.692 N/A ALA 438.A N GLU 434.A O no hydrogen 2.894 N/A ALA 439.A N ILE 435.A O no hydrogen 2.989 N/A ALA 440.A N LEU 436.A O no hydrogen 2.902 N/A GLN 441.A N ALA 438.A O no hydrogen 3.288 N/A GLN 441.A NE2 THR 437.A O no hydrogen 2.657 N/A HIS 442.A N ALA 439.A O no hydrogen 3.056 N/A SER 443.A N ALA 440.A O no hydrogen 3.038 N/A SER 443.A OG GLU 445.A OE1 no hydrogen 3.351 N/A GLU 445.A N GLU 445.A OE1 no hydrogen 2.948 N/A LEU 446.A N SER 443.A OG no hydrogen 3.080 N/A LYS 447.A N SER 443.A O no hydrogen 3.001 N/A ILE 448.A N PRO 444.A O no hydrogen 3.028 N/A ALA 449.A N GLU 445.A O no hydrogen 2.926 N/A MET 450.A N LEU 446.A O no hydrogen 2.844 N/A GLU 451.A N LYS 447.A O no hydrogen 3.213 N/A THR 452.A N ILE 448.A O no hydrogen 2.864 N/A THR 452.A N ALA 449.A O no hydrogen 3.156 N/A THR 452.A OG1 ILE 448.A O no hydrogen 2.739 N/A TRP 453.A N ALA 449.A O no hydrogen 3.403 N/A