Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7sse_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A N GLU 297.A O no hydrogen 3.081 N/A ARG 3.A NH1 GLU 297.A OE1 no hydrogen 2.532 N/A ILE 5.A N LEU 295.A O no hydrogen 2.776 N/A SER 6.A N LEU 295.A O no hydrogen 3.354 N/A SER 6.A OG.A VAL 44.A O no hydrogen 2.744 N/A SER 6.A OG.B VAL 44.A O no hydrogen 3.083 N/A SER 6.A OG.B PHE 45.A O no hydrogen 3.458 N/A PHE 8.A N CYS 293.A O no hydrogen 2.984 N/A ARG 9.A NH1 GLU 13.A O no hydrogen 2.748 N/A ARG 9.A NH2 GLU 13.A O no hydrogen 2.883 N/A ARG 9.A NH2 ASP 14.A O no hydrogen 3.087 N/A ARG 9.A NH2 ASP 290.A OD1 no hydrogen 3.169 N/A GLU 10.A N SER 16.A OG no hydrogen 2.820 N/A ALA 11.A N TYR 42.A OH no hydrogen 2.894 N/A GLU 13.A N GLU 10.A O no hydrogen 3.354 N/A SER 16.A N ASP 290.A OD1 no hydrogen 2.923 N/A SER 16.A OG THR 291.A O no hydrogen 2.674 N/A GLY 17.A N GLU 10.A OE1 no hydrogen 2.873 N/A THR 19.A N GLY 33.A O no hydrogen 2.827 N/A THR 19.A OG1 ILE 60.A O no hydrogen 2.526 N/A CYS 20.A SG ILE 60.A O no hydrogen 3.724 N/A CYS 21.A N ASP 266.A OD2 no hydrogen 2.878 N/A ALA 22.A N MET 31.A O no hydrogen 2.883 N/A SER 24.A N PHE 29.A O no hydrogen 2.943 N/A SER 24.A OG ARG 26.A O no hydrogen 2.544 N/A SER 24.A OG PHE 29.A O no hydrogen 2.938 N/A ARG 26.A N SER 24.A OG no hydrogen 2.976 N/A PHE 29.A N ARG 26.A O no hydrogen 3.363 N/A LEU 30.A N TYR 42.A O no hydrogen 2.911 N/A MET 31.A N ALA 22.A O no hydrogen 2.776 N/A LEU 32.A N LYS 40.A O no hydrogen 2.806 N/A GLY 33.A N CYS 20.A O no hydrogen 3.033 N/A THR 34.A N GLN 38.A O no hydrogen 2.949 N/A THR 34.A OG1 THR 36.A OG1 no hydrogen 3.235 N/A THR 34.A OG1 GLN 38.A O no hydrogen 3.481 N/A CYS 35.A N GLY 17.A O no hydrogen 2.808 N/A CYS 35.A SG GLY 17.A O no hydrogen 3.872 N/A THR 36.A N THR 34.A OG1 no hydrogen 3.418 N/A THR 36.A OG1 THR 34.A OG1 no hydrogen 3.235 N/A GLY 37.A N THR 34.A O no hydrogen 3.049 N/A GLN 38.A N THR 34.A OG1 no hydrogen 3.152 N/A GLN 38.A NE2 ASN 54.A OD1 no hydrogen 2.914 N/A LEU 39.A N TYR 53.A O no hydrogen 2.836 N/A LYS 40.A N LEU 32.A O no hydrogen 2.699 N/A LYS 40.A NZ GLN 38.A OE1 no hydrogen 3.306 N/A LYS 40.A NZ GLU 49.A OE2 no hydrogen 3.445 N/A LYS 40.A NZ SER 52.A OG no hydrogen 2.772 N/A LEU 41.A N ALA 51.A O no hydrogen 2.875 N/A TYR 42.A N LEU 30.A O no hydrogen 2.912 N/A TYR 42.A OH GLU 49.A OE1 no hydrogen 2.625 N/A ASN 43.A N GLN 48.A O no hydrogen 2.968 N/A VAL 44.A N ARG 28.A O no hydrogen 3.019 N/A PHE 45.A N ASN 43.A OD1 no hydrogen 3.020 N/A SER 46.A N ASN 43.A OD1 no hydrogen 3.001 N/A GLY 47.A N ASN 43.A O no hydrogen 2.817 N/A GLN 48.A N SER 46.A OG no hydrogen 3.177 N/A GLN 48.A NE2 SER 46.A O no hydrogen 2.898 N/A GLU 50.A N LEU 41.A O no hydrogen 2.800 N/A ALA 51.A N LEU 41.A O no hydrogen 3.363 N/A TYR 53.A N LEU 39.A O no hydrogen 2.869 N/A CYS 55.A N GLY 37.A O no hydrogen 3.054 N/A HIS 56.A N GLY 37.A O no hydrogen 2.960 N/A HIS 56.A NE2 THR 74.A OG1 no hydrogen 2.694 N/A SER 58.A OG THR 77.A OG1.B no hydrogen 3.001 N/A SER 58.A OG SER 79.A OG no hydrogen 2.548 N/A ILE 60.A N THR 34.A O no hydrogen 3.036 N/A THR 61.A N SER 75.A O no hydrogen 2.818 N/A THR 61.A OG1 SER 75.A O no hydrogen 3.240 N/A GLU 64.A N LEU 73.A O no hydrogen 2.905 N/A SER 66.A N LEU 71.A O no hydrogen 2.777 N/A SER 66.A OG ASP 68.A OD1 no hydrogen 2.791 N/A SER 66.A OG LEU 71.A O no hydrogen 3.195 N/A ARG 67.A N GLN 111.A OE1 no hydrogen 2.866 N/A ARG 67.A NH1 LYS 108.A O no hydrogen 2.876 N/A ARG 67.A NH2 LYS 108.A O no hydrogen 3.018 N/A ARG 67.A NH2 HIS 109.A O no hydrogen 2.982 N/A GLY 69.A N SER 66.A O no hydrogen 3.181 N/A SER 70.A N ASP 68.A OD1 no hydrogen 2.874 N/A SER 70.A OG ASP 68.A OD1 no hydrogen 2.623 N/A SER 70.A OG ASP 68.A OD2 no hydrogen 3.200 N/A LEU 71.A N SER 66.A OG no hydrogen 2.985 N/A LEU 72.A N TRP 86.A O no hydrogen 2.894 N/A LEU 73.A N GLU 64.A O no hydrogen 2.893 N/A THR 74.A N ALA 84.A O no hydrogen 2.979 N/A THR 74.A OG1 HIS 56.A NE2 no hydrogen 2.694 N/A SER 75.A N HIS 62.A O no hydrogen 3.040 N/A SER 75.A OG SER 83.A OG no hydrogen 2.817 N/A ALA 76.A N LEU 82.A O no hydrogen 2.682 N/A THR 77.A N.A SER 58.A OG no hydrogen 3.237 N/A THR 77.A N.B SER 58.A OG no hydrogen 3.243 N/A THR 77.A OG1.A ALA 59.A O no hydrogen 2.869 N/A THR 77.A OG1.B SER 58.A OG no hydrogen 3.001 N/A TRP 78.A N SER 58.A OG no hydrogen 3.196 N/A SER 79.A OG ASN 57.A OD1 no hydrogen 2.634 N/A SER 79.A OG SER 58.A OG no hydrogen 2.548 N/A LEU 82.A N THR 99.A O no hydrogen 3.127 N/A SER 83.A N PHE 98.A O no hydrogen 3.364 N/A SER 83.A OG SER 75.A OG no hydrogen 2.817 N/A SER 83.A OG ASP 101.A O no hydrogen 2.637 N/A ALA 84.A N THR 74.A O no hydrogen 2.943 N/A LEU 85.A N HIS 96.A O no hydrogen 2.829 N/A TRP 86.A N LEU 72.A O no hydrogen 2.780 N/A TRP 86.A NE1 THR 74.A OG1 no hydrogen 2.793 N/A GLY 87.A N ASP 93.A O no hydrogen 2.763 N/A MET 88.A N SER 70.A O no hydrogen 2.907 N/A ASP 93.A N GLY 87.A O no hydrogen 3.272 N/A LYS 95.A N LEU 85.A O no hydrogen 2.769 N/A LYS 95.A NZ ASP 93.A OD2 no hydrogen 3.095 N/A HIS 96.A N LEU 85.A O no hydrogen 3.349 N/A HIS 96.A NE2 GLN 128.A O no hydrogen 2.983 N/A PHE 98.A N SER 83.A O no hydrogen 2.800 N/A ASP 101.A N PHE 98.A O no hydrogen 3.402 N/A HIS 102.A N.A THR 117.A O no hydrogen 3.010 N/A HIS 102.A N.B THR 117.A O no hydrogen 2.985 N/A TYR 103.A OH GLU 105.A OE2 no hydrogen 2.627 N/A GLU 105.A N ILE 115.A O no hydrogen 2.920 N/A PHE 106.A N GLU 64.A OE1 no hydrogen 2.934 N/A SER 107.A N ARG 113.A O no hydrogen 2.991 N/A SER 107.A OG SER 110.A O no hydrogen 2.674 N/A SER 107.A OG ARG 113.A O no hydrogen 3.149 N/A LYS 108.A N ASP 156.A OD1 no hydrogen 2.685 N/A LYS 108.A NZ PHE 152.A O no hydrogen 3.096 N/A HIS 109.A N ASP 156.A OD1 no hydrogen 3.293 N/A HIS 109.A N ASP 156.A OD2 no hydrogen 3.123 N/A SER 110.A N ASP 156.A OD2 no hydrogen 3.228 N/A ARG 113.A N SER 107.A OG no hydrogen 3.084 N/A ARG 113.A NE ASP 112.A OD1 no hydrogen 3.375 N/A VAL 114.A N TYR 125.A O no hydrogen 2.980 N/A ILE 115.A N GLU 105.A O no hydrogen 2.851 N/A GLY 116.A N HIS 123.A O no hydrogen 2.729 N/A THR 117.A N TYR 103.A O no hydrogen 2.812 N/A LYS 118.A N ILE 121.A O no hydrogen 2.908 N/A GLY 119.A N HIS 102.A NE2.A no hydrogen 3.299 N/A ILE 121.A N LYS 118.A O no hydrogen 2.883 N/A ALA 122.A N LEU 136.A O no hydrogen 3.100 N/A HIS 123.A N GLY 116.A O no hydrogen 2.869 N/A HIS 123.A ND1 ASP 101.A OD1 no hydrogen 2.647 N/A ILE 124.A N LEU 134.A O no hydrogen 2.932 N/A TYR 125.A N VAL 114.A O no hydrogen 2.792 N/A TYR 125.A OH ASP 101.A OD2 no hydrogen 2.603 N/A ASP 126.A N ASN 131.A O no hydrogen 2.998 N/A ILE 127.A N ASP 112.A O no hydrogen 3.097 N/A THR 129.A N ASP 126.A OD2 no hydrogen 2.892 N/A THR 129.A OG1 ASP 126.A OD2 no hydrogen 3.196 N/A GLY 130.A N ASP 126.A O no hydrogen 2.759 N/A ASN 131.A N THR 129.A OG1 no hydrogen 3.067 N/A LYS 132.A NZ GLU 100.A OE1 no hydrogen 2.743 N/A LEU 133.A N ILE 124.A O no hydrogen 2.735 N/A LEU 134.A N ILE 124.A O no hydrogen 3.343 N/A LEU 136.A N ALA 122.A O no hydrogen 2.775 N/A ASP 140.A N ASN 138.A OD1 no hydrogen 2.866 N/A LEU 141.A N ASN 138.A O no hydrogen 3.186 N/A ASN 143.A N ASP 162.A OD2 no hydrogen 2.890 N/A ASN 143.A ND2 ASP 162.A O no hydrogen 2.902 N/A ASN 143.A ND2 PHE 177.A O no hydrogen 3.278 N/A ASN 144.A N ASP 162.A OD2 no hydrogen 2.768 N/A ASN 144.A ND2 ASP 120.A OD2 no hydrogen 3.110 N/A TYR 145.A N ASP 162.A OD1 no hydrogen 2.766 N/A LYS 146.A N MET 182.A O no hydrogen 2.973 N/A ARG 147.A N ASN 183.A O no hydrogen 2.915 N/A ASN 148.A N TYR 145.A O no hydrogen 3.355 N/A ASN 148.A ND2 GLY 119.A O no hydrogen 2.973 N/A ASN 148.A ND2 ASN 161.A OD1 no hydrogen 2.930 N/A CYS 149.A N.A SER 185.A OG no hydrogen 3.165 N/A CYS 149.A N.B SER 185.A OG no hydrogen 3.145 N/A CYS 149.A SG.B ARG 147.A O no hydrogen 3.880 N/A ALA 150.A N THR 117.A OG1 no hydrogen 2.846 N/A THR 151.A N LEU 160.A O no hydrogen 3.070 N/A THR 151.A OG1 GLU 105.A OE1 no hydrogen 2.663 N/A THR 151.A OG1 PHE 152.A O no hydrogen 3.331 N/A ASN 153.A N LEU 158.A O no hydrogen 3.005 N/A THR 155.A OG1 ASP 157.A OD2 no hydrogen 2.818 N/A ASP 156.A N ASN 153.A O no hydrogen 3.059 N/A LEU 158.A N ASN 153.A OD1 no hydrogen 2.885 N/A VAL 159.A N TRP 166.A O no hydrogen 3.060 N/A LEU 160.A N THR 151.A O no hydrogen 2.868 N/A ASN 161.A N VAL 164.A O no hydrogen 2.897 N/A ASN 161.A ND2 ASP 120.A O no hydrogen 2.974 N/A ASP 162.A N ASN 148.A OD1 no hydrogen 2.746 N/A VAL 164.A N ASN 161.A O no hydrogen 2.910 N/A LEU 165.A N HIS 175.A O no hydrogen 2.740 N/A TRP 166.A N VAL 159.A O no hydrogen 2.774 N/A ASP 167.A N GLN 172.A O no hydrogen 2.883 N/A VAL 168.A N ASP 157.A O no hydrogen 3.105 N/A ARG 169.A NH1 ASP 157.A OD1 no hydrogen 3.223 N/A ARG 169.A NH2 ASP 157.A OD1 no hydrogen 2.851 N/A SER 170.A N ASP 167.A OD2 no hydrogen 3.051 N/A SER 170.A OG ASP 167.A O no hydrogen 3.524 N/A SER 170.A OG ASP 167.A OD2 no hydrogen 2.994 N/A GLN 172.A N ASP 167.A O no hydrogen 3.296 N/A GLN 172.A N SER 170.A OG no hydrogen 3.261 N/A ILE 174.A N LEU 165.A O no hydrogen 2.800 N/A HIS 175.A N LEU 165.A O no hydrogen 3.436 N/A LYS 176.A NZ ASN 143.A OD1 no hydrogen 3.559 N/A PHE 177.A N GLY 163.A O no hydrogen 2.930 N/A LYS 179.A NZ ASN 143.A O no hydrogen 2.688 N/A ASN 181.A ND2 ILE 184.A O no hydrogen 3.010 N/A ASN 183.A N ASN 181.A OD1 no hydrogen 3.027 N/A ASN 183.A ND2 GLN 218.A OE1 no hydrogen 2.771 N/A ILE 184.A N ASN 181.A OD1 no hydrogen 2.883 N/A SER 185.A OG ASN 148.A OD1 no hydrogen 3.418 N/A VAL 187.A N ILE 196.A O no hydrogen 2.880 N/A HIS 189.A N GLU 194.A O no hydrogen 2.991 N/A HIS 189.A NE2 ALA 249.A O no hydrogen 2.880 N/A ASN 191.A N HIS 189.A ND1 no hydrogen 2.998 N/A ASN 191.A ND2 GLU 194.A OE2 no hydrogen 2.943 N/A GLY 192.A N HIS 189.A O no hydrogen 2.944 N/A LEU 193.A N ASN 191.A OD1 no hydrogen 2.854 N/A VAL 195.A N TRP 202.A O no hydrogen 2.929 N/A ILE 196.A N VAL 187.A O no hydrogen 2.853 N/A ILE 197.A N GLU 200.A O no hydrogen 2.812 N/A ASN 198.A ND2 ASP 217.A OD1 no hydrogen 2.991 N/A THR 199.A OG1 GLU 200.A OE1 no hydrogen 3.265 N/A THR 199.A OG1 GLU 200.A OE2 no hydrogen 2.662 N/A GLU 200.A N ILE 197.A O no hydrogen 3.088 N/A ILE 201.A N HIS 211.A O no hydrogen 3.012 N/A TRP 202.A N VAL 195.A O no hydrogen 2.771 N/A ASP 203.A N HIS 208.A O no hydrogen 2.829 N/A LEU 204.A N LEU 193.A O no hydrogen 2.926 N/A THR 206.A N ASP 203.A OD2 no hydrogen 2.979 N/A THR 206.A OG1 ASP 203.A OD2 no hydrogen 2.837 N/A HIS 208.A N THR 206.A OG1 no hydrogen 3.146 N/A LEU 210.A N ILE 201.A O no hydrogen 2.756 N/A HIS 211.A N ILE 201.A O no hydrogen 3.452 N/A VAL 213.A N THR 199.A O no hydrogen 2.688 N/A LEU 216.A N VAL 213.A O no hydrogen 3.052 N/A ASP 217.A N PRO 214.A O no hydrogen 3.057 N/A GLN 218.A N ASN 198.A OD1 no hydrogen 2.711 N/A GLN 218.A NE2 ASN 181.A OD1 no hydrogen 3.120 N/A GLN 218.A NE2 ASP 217.A OD1 no hydrogen 2.985 N/A CYS 219.A N LEU 216.A O no hydrogen 3.137 N/A CYS 219.A SG ASP 217.A O no hydrogen 3.796 N/A ARG 220.A N ALA 233.A O no hydrogen 3.157 N/A ARG 220.A NH1 ASP 266.A OD1 no hydrogen 3.337 N/A ARG 220.A NH2 ASP 266.A OD1 no hydrogen 3.011 N/A VAL 222.A N TYR 231.A O no hydrogen 2.883 N/A ASN 224.A N VAL 229.A O no hydrogen 3.035 N/A ASN 224.A ND2 THR 228.A OG1 no hydrogen 3.027 N/A HIS 225.A N ASP 273.A OD1 no hydrogen 2.863 N/A HIS 225.A ND1 ASP 273.A OD1 no hydrogen 3.047 N/A THR 226.A N ASP 273.A OD2 no hydrogen 2.812 N/A THR 226.A OG1 THR 228.A OG1 no hydrogen 3.168 N/A THR 226.A OG1 ASP 273.A OD2 no hydrogen 3.127 N/A GLY 227.A N ASN 224.A O no hydrogen 3.186 N/A THR 228.A N ASN 224.A OD1 no hydrogen 2.943 N/A THR 228.A OG1 THR 226.A OG1 no hydrogen 3.168 N/A VAL 229.A N ASN 224.A OD1 no hydrogen 3.171 N/A MET 230.A N PHE 247.A O no hydrogen 2.923 N/A TYR 231.A N VAL 222.A O no hydrogen 2.679 N/A GLY 232.A N ARG 245.A O no hydrogen 2.738 N/A ALA 233.A N ARG 220.A O no hydrogen 3.419 N/A LEU 235.A N GLN 218.A O no hydrogen 2.830 N/A GLN 236.A N PRO 239.A O no hydrogen 2.742 N/A GLN 236.A NE2 SER 238.A O.A no hydrogen 2.687 N/A GLN 236.A NE2 SER 238.A O.B no hydrogen 2.680 N/A SER 238.A OG.A PHE 240.A O no hydrogen 3.395 N/A SER 238.A OG.A ILE 264.A O no hydrogen 2.417 N/A SER 238.A OG.B PHE 240.A O no hydrogen 3.134 N/A PHE 240.A N SER 238.A OG.A no hydrogen 2.918 N/A GLY 241.A N MET 234.A O no hydrogen 3.100 N/A SER 242.A OG ASP 259.A OD1 no hydrogen 2.832 N/A PHE 244.A N ILE 258.A O no hydrogen 2.973 N/A ARG 245.A N GLY 232.A O no hydrogen 2.662 N/A THR 246.A N ALA 256.A O no hydrogen 2.906 N/A THR 246.A OG1 ALA 256.A O no hydrogen 3.495 N/A PHE 247.A N MET 230.A O no hydrogen 2.821 N/A ASN 248.A N LYS 253.A O no hydrogen 2.850 N/A ALA 249.A N THR 228.A O no hydrogen 3.009 N/A THR 250.A N ASN 248.A OD1 no hydrogen 2.879 N/A THR 250.A OG1 ASN 248.A OD1 no hydrogen 2.621 N/A TYR 252.A N ASN 248.A O no hydrogen 2.662 N/A TYR 252.A OH GLU 194.A OE1 no hydrogen 2.463 N/A LYS 253.A N ASP 251.A OD1 no hydrogen 3.031 N/A ILE 255.A N THR 246.A O no hydrogen 2.891 N/A ALA 256.A N THR 246.A OG1 no hydrogen 3.102 N/A ILE 258.A N PHE 244.A O no hydrogen 2.898 N/A VAL 260.A N SER 242.A O no hydrogen 2.795 N/A LYS 261.A N ASP 259.A OD1 no hydrogen 2.903 N/A ARG 262.A NH2 LYS 261.A O no hydrogen 2.697 N/A ASN 263.A ND2 GLN 236.A OE1 no hydrogen 3.637 N/A ASN 263.A ND2 PHE 240.A O no hydrogen 3.187 N/A ASN 263.A ND2 ASP 285.A OD1 no hydrogen 3.407 N/A ILE 264.A N GLY 241.A O no hydrogen 2.920 N/A PHE 265.A N ILE 279.A O no hydrogen 2.752 N/A LEU 267.A N ASP 266.A OD1 no hydrogen 2.914 N/A CYS 268.A N ALA 277.A O no hydrogen 2.977 N/A THR 269.A OG1 HIS 225.A ND1 no hydrogen 3.390 N/A THR 269.A OG1 ASP 273.A OD1 no hydrogen 3.069 N/A ASP 273.A N ASP 270.A O no hydrogen 2.933 N/A CYS 274.A SG LYS 272.A O no hydrogen 3.748 N/A TYR 275.A N ASP 270.A OD1 no hydrogen 2.832 N/A LEU 276.A N TYR 296.A O no hydrogen 2.858 N/A ALA 277.A N CYS 268.A O no hydrogen 2.867 N/A VAL 278.A N ARG 294.A O no hydrogen 2.875 N/A ILE 279.A N ASP 266.A O no hydrogen 2.903 N/A GLU 280.A N VAL 292.A O no hydrogen 2.935 N/A ASN 281.A N ASN 263.A O no hydrogen 2.917 N/A ASN 281.A ND2 ASN 288.A O no hydrogen 2.842 N/A GLN 282.A N ASP 290.A O no hydrogen 3.147 N/A GLN 282.A NE2 ASP 290.A O no hydrogen 3.102 N/A SER 283.A OG MET 284.A O no hydrogen 3.487 N/A ASP 285.A N ASN 263.A OD1 no hydrogen 2.701 N/A ALA 286.A N SER 283.A O no hydrogen 3.296 N/A ASP 290.A N ASN 281.A OD1 no hydrogen 2.875 N/A THR 291.A N SER 16.A O no hydrogen 2.952 N/A THR 291.A OG1 SER 16.A O no hydrogen 3.465 N/A THR 291.A OG1 PHE 18.A O no hydrogen 2.778 N/A VAL 292.A N GLU 280.A O no hydrogen 2.923 N/A CYS 293.A N PHE 8.A O no hydrogen 2.853 N/A ARG 294.A N VAL 278.A O no hydrogen 2.841 N/A LEU 295.A N SER 6.A O no hydrogen 2.870 N/A TYR 296.A N LEU 276.A O no hydrogen 2.785 N/A TYR 296.A OH GLU 280.A OE2 no hydrogen 3.194 N/A GLU 297.A N ARG 3.A O no hydrogen 2.884 N/A VAL 298.A N CYS 274.A O no hydrogen 2.809 N/A