Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7sx8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 GLU 95.A O no hydrogen 3.459 N/A THR 2.A OG1 ALA 3.A O no hydrogen 3.473 N/A LEU 4.A N PRO 97.A O no hydrogen 2.500 N/A VAL 5.A N GLY 16.A O no hydrogen 2.858 N/A CYS 6.A N LEU 99.A O no hydrogen 2.816 N/A CYS 6.A SG LYS 14.A O no hydrogen 3.326 N/A ASP 7.A N LYS 14.A O no hydrogen 2.508 N/A ASN 8.A N THR 101.A OG1 no hydrogen 2.831 N/A ASN 8.A ND2 THR 101.A O no hydrogen 2.763 N/A LYS 14.A N ASP 7.A O no hydrogen 2.430 N/A LYS 14.A NZ LEU 12.A O no hydrogen 3.025 N/A ARG 24.A NH1 GLU 88.A O no hydrogen 3.549 N/A SER 29.A N GLY 11.A O no hydrogen 2.528 N/A SER 29.A OG GLY 9.A O no hydrogen 3.329 N/A SER 29.A OG SER 10.A O no hydrogen 2.309 N/A VAL 31.A N LYS 64.A O no hydrogen 2.665 N/A GLY 32.A N TYR 49.A O no hydrogen 3.205 N/A ARG 33.A NH2 ASP 76.A OD1 no hydrogen 3.436 N/A GLN 45.A N GLN 45.A OE1 no hydrogen 2.294 N/A GLN 45.A NE2 GLY 42.A O no hydrogen 2.422 N/A SER 48.A N ASP 47.A OD1 no hydrogen 2.803 N/A SER 48.A OG ASP 47.A O no hydrogen 2.842 N/A TYR 49.A N GLY 32.A O no hydrogen 2.389 N/A VAL 50.A N GLU 53.A OE2 no hydrogen 2.433 N/A GLY 51.A N ILE 30.A O no hydrogen 2.881 N/A ALA 54.A N GLY 51.A O no hydrogen 2.937 N/A GLN 55.A N GLY 51.A O no hydrogen 2.918 N/A GLN 55.A NE2 GLU 202.A OE1 no hydrogen 2.717 N/A SER 56.A N ASP 52.A O no hydrogen 2.891 N/A SER 56.A OG ASP 52.A O no hydrogen 2.883 N/A SER 56.A OG GLU 53.A O no hydrogen 3.510 N/A LYS 57.A N ALA 54.A O no hydrogen 3.225 N/A LYS 57.A NZ GLU 53.A O no hydrogen 3.497 N/A LEU 63.A N THR 198.A OG1 no hydrogen 2.899 N/A LYS 64.A N VAL 31.A O no hydrogen 2.407 N/A GLU 68.A N ILE 70.A O no hydrogen 3.102 N/A ILE 70.A N GLU 68.A O no hydrogen 3.237 N/A THR 72.A OG1 GLU 68.A OE1 no hydrogen 3.154 N/A THR 72.A OG1 GLU 68.A OE2 no hydrogen 3.398 N/A THR 72.A OG1 ASN 73.A OD1 no hydrogen 3.170 N/A ASN 73.A N ASN 73.A OD1 no hydrogen 2.541 N/A ASP 76.A N ASP 75.A OD1 no hydrogen 2.389 N/A GLU 78.A N TRP 74.A O no hydrogen 2.894 N/A LYS 79.A NZ ASP 75.A O no hydrogen 2.823 N/A LYS 79.A NZ ASP 76.A OD1 no hydrogen 2.863 N/A ILE 80.A N ASP 76.A O no hydrogen 2.903 N/A TRP 81.A N MET 77.A O no hydrogen 2.880 N/A HIS 82.A N GLU 78.A O no hydrogen 2.914 N/A HIS 83.A N LYS 79.A O no hydrogen 2.873 N/A THR 84.A N ILE 80.A O no hydrogen 2.901 N/A THR 84.A OG1 ILE 80.A O no hydrogen 2.891 N/A PHE 85.A N TRP 81.A O no hydrogen 2.918 N/A TYR 86.A N HIS 82.A O no hydrogen 3.299 N/A ASN 87.A ND2 HIS 83.A ND1 no hydrogen 3.134 N/A ASN 87.A ND2 HIS 83.A O no hydrogen 3.288 N/A GLU 88.A N PHE 85.A O no hydrogen 3.361 N/A ARG 90.A NH1 ASN 87.A O no hydrogen 3.213 N/A GLU 95.A N ALA 92.A O no hydrogen 3.243 N/A HIS 96.A N PRO 93.A O no hydrogen 3.391 N/A HIS 96.A ND1 THR 2.A O no hydrogen 2.965 N/A LEU 99.A N LEU 4.A O no hydrogen 2.375 N/A LEU 100.A N TYR 128.A O no hydrogen 2.695 N/A THR 101.A OG1 CYS 6.A O no hydrogen 3.294 N/A THR 101.A OG1 ASP 7.A OD1 no hydrogen 3.217 N/A THR 101.A OG1 ASN 8.A OD1 no hydrogen 2.243 N/A GLU 102.A N ALA 130.A O no hydrogen 3.091 N/A ASN 110.A N PRO 107.A O no hydrogen 3.174 N/A ASN 110.A ND2 ASN 106.A OD1 no hydrogen 3.165 N/A GLU 112.A N LYS 108.A O no hydrogen 2.896 N/A LYS 113.A N ALA 109.A O no hydrogen 2.901 N/A MET 114.A N ASN 110.A O no hydrogen 2.933 N/A THR 115.A N ARG 111.A O no hydrogen 2.936 N/A THR 115.A OG1 ARG 111.A O no hydrogen 2.421 N/A GLN 116.A N GLU 112.A O no hydrogen 2.907 N/A ILE 117.A N LYS 113.A O no hydrogen 2.901 N/A MET 118.A N MET 114.A O no hydrogen 3.356 N/A PHE 119.A N THR 115.A O no hydrogen 2.915 N/A GLU 120.A N GLN 116.A O no hydrogen 2.698 N/A PHE 122.A N ILE 117.A O no hydrogen 3.242 N/A ASN 123.A N GLU 94.A OE2 no hydrogen 3.379 N/A MET 127.A N ILE 352.A O no hydrogen 2.938 N/A TYR 128.A N THR 98.A O no hydrogen 3.377 N/A ALA 130.A N LEU 100.A O no hydrogen 2.783 N/A GLN 132.A NE2 ASN 8.A OD1 no hydrogen 3.244 N/A LEU 135.A N ILE 131.A O no hydrogen 3.061 N/A SER 136.A N GLN 132.A O no hydrogen 2.906 N/A LEU 137.A N VAL 134.A O no hydrogen 3.250 N/A TYR 138.A N LEU 135.A O no hydrogen 3.127 N/A ALA 139.A N SER 136.A O no hydrogen 3.328 N/A SER 140.A OG LEU 137.A O no hydrogen 2.935 N/A GLY 141.A N TYR 138.A O no hydrogen 3.303 N/A GLY 145.A N ILE 160.A O no hydrogen 2.544 N/A LEU 148.A N VAL 293.A O no hydrogen 3.066 N/A ASP 149.A N HIS 156.A O no hydrogen 3.438 N/A SER 150.A N SER 295.A O no hydrogen 3.463 N/A SER 150.A OG THR 155.A OG1 no hydrogen 3.021 N/A SER 150.A OG THR 298.A OG1 no hydrogen 3.118 N/A GLY 151.A N VAL 154.A O no hydrogen 2.882 N/A THR 155.A N LEU 173.A O no hydrogen 2.708 N/A THR 155.A OG1 SER 150.A OG no hydrogen 3.021 N/A THR 155.A OG1 LEU 175.A O no hydrogen 2.821 N/A HIS 156.A N ASP 149.A O no hydrogen 3.248 N/A ILE 160.A N GLY 145.A O no hydrogen 3.411 N/A TYR 161.A N TYR 164.A O no hydrogen 2.618 N/A GLU 162.A N THR 144.A OG1 no hydrogen 2.835 N/A GLY 163.A N THR 143.A O no hydrogen 2.949 N/A TYR 164.A N TYR 161.A O no hydrogen 2.978 N/A ALA 169.A N LEU 166.A O no hydrogen 3.158 N/A ARG 172.A NH1 LEU 105.A O no hydrogen 3.213 N/A LEU 173.A N THR 155.A O no hydrogen 2.485 N/A GLY 177.A N ASP 152.A O no hydrogen 2.592 N/A ARG 178.A N ASP 152.A O no hydrogen 2.522 N/A ARG 178.A NE ASP 152.A OD2 no hydrogen 3.360 N/A ARG 178.A NH1 ILE 67.A O no hydrogen 2.434 N/A ARG 178.A NH2 ILE 67.A O no hydrogen 2.839 N/A ARG 178.A NH2 ASP 152.A OD2 no hydrogen 3.481 N/A THR 181.A N GLY 177.A O no hydrogen 3.018 N/A THR 181.A OG1 GLY 177.A O no hydrogen 2.635 N/A ASP 182.A N ARG 178.A O no hydrogen 2.912 N/A TYR 183.A N ASP 179.A O no hydrogen 2.856 N/A LEU 184.A N LEU 180.A O no hydrogen 2.911 N/A MET 185.A N THR 181.A O no hydrogen 2.910 N/A LYS 186.A N ASP 182.A O no hydrogen 2.901 N/A ILE 187.A N TYR 183.A O no hydrogen 2.910 N/A LEU 188.A N LEU 184.A O no hydrogen 2.898 N/A THR 189.A N LYS 186.A O no hydrogen 3.447 N/A THR 189.A OG1 LYS 186.A O no hydrogen 2.710 N/A GLU 190.A N ILE 187.A O no hydrogen 3.305 N/A ARG 191.A NE GLU 248.A OE1 no hydrogen 2.513 N/A ARG 201.A N THR 198.A O no hydrogen 2.984 N/A VAL 204.A N GLU 200.A O no hydrogen 2.903 N/A ARG 205.A N ARG 201.A O no hydrogen 2.877 N/A ARG 205.A NE GLU 202.A OE1 no hydrogen 3.424 N/A ARG 205.A NH1 GLU 209.A OE2 no hydrogen 2.893 N/A ARG 205.A NH2 GLU 202.A OE1 no hydrogen 2.699 N/A ASP 206.A N GLU 202.A O no hydrogen 2.900 N/A ILE 207.A N ILE 203.A O no hydrogen 2.905 N/A LYS 208.A N VAL 204.A O no hydrogen 2.873 N/A LYS 208.A NZ TYR 301.A OH no hydrogen 3.432 N/A GLU 209.A N ARG 205.A O no hydrogen 2.880 N/A LYS 210.A N ASP 206.A O no hydrogen 2.945 N/A LEU 211.A N ILE 207.A O no hydrogen 2.858 N/A CYS 212.A N LYS 208.A O no hydrogen 3.005 N/A CYS 212.A SG ARG 249.A O no hydrogen 3.072 N/A GLU 221.A N ASP 217.A O no hydrogen 3.073 N/A MET 222.A N PHE 218.A O no hydrogen 2.887 N/A ALA 223.A N GLU 219.A O no hydrogen 2.927 N/A THR 224.A N ASN 220.A O no hydrogen 2.875 N/A THR 224.A OG1 ASN 220.A O no hydrogen 2.669 N/A ALA 225.A N GLU 221.A O no hydrogen 2.895 N/A ALA 226.A N MET 222.A O no hydrogen 2.899 N/A SER 227.A N ALA 223.A O no hydrogen 2.903 N/A SER 227.A OG ALA 223.A O no hydrogen 2.653 N/A SER 228.A N THR 224.A O no hydrogen 2.878 N/A SER 228.A OG THR 224.A O no hydrogen 2.588 N/A LYS 233.A N ILE 245.A O no hydrogen 3.435 N/A SER 234.A OG THR 244.A OG1 no hydrogen 2.515 N/A TYR 235.A N ILE 243.A O no hydrogen 2.815 N/A LEU 237.A N GLN 241.A O no hydrogen 2.996 N/A GLN 241.A N ASP 239.A OD1 no hydrogen 3.448 N/A ILE 243.A N TYR 235.A O no hydrogen 3.076 N/A THR 244.A N TYR 193.A OH no hydrogen 3.219 N/A THR 244.A OG1 SER 234.A OG no hydrogen 2.515 N/A ILE 245.A N LYS 233.A O no hydrogen 3.219 N/A ARG 249.A NH1 LEU 231.A O no hydrogen 3.226 N/A ARG 251.A NE TYR 183.A OH no hydrogen 3.495 N/A ARG 251.A NH1 GLU 190.A OE1 no hydrogen 3.246 N/A ARG 251.A NH2 TYR 183.A OH no hydrogen 3.347 N/A CYS 252.A SG LEU 180.A O no hydrogen 3.089 N/A GLU 254.A N ARG 251.A O no hydrogen 3.265 N/A THR 255.A N CYS 252.A O no hydrogen 3.222 N/A THR 255.A OG1 CYS 252.A O no hydrogen 3.062 N/A LEU 256.A N PRO 253.A O no hydrogen 3.311 N/A GLN 258.A N GLU 254.A O no hydrogen 2.905 N/A ILE 262.A N PRO 259.A O no hydrogen 3.338 N/A GLY 263.A N PRO 259.A O no hydrogen 3.204 N/A ILE 269.A N LEU 256.A O no hydrogen 3.138 N/A THR 272.A N GLY 268.A O no hydrogen 3.261 N/A THR 272.A OG1 GLY 268.A O no hydrogen 2.520 N/A TYR 274.A OH LEU 315.A O no hydrogen 3.173 N/A ASN 275.A N GLU 271.A O no hydrogen 2.894 N/A SER 276.A N THR 272.A O no hydrogen 2.908 N/A SER 276.A OG ALA 169.A O no hydrogen 2.947 N/A ILE 277.A N THR 273.A O no hydrogen 2.903 N/A MET 278.A N TYR 274.A O no hydrogen 2.903 N/A LYS 279.A N ASN 275.A O no hydrogen 3.062 N/A LYS 279.A N SER 276.A O no hydrogen 3.155 N/A CYS 280.A N ILE 277.A O no hydrogen 2.912 N/A CYS 280.A SG SER 276.A O no hydrogen 3.235 N/A LYS 286.A NZ ASP 287.A OD1 no hydrogen 2.879 N/A LEU 288.A N ARG 285.A O no hydrogen 3.123 N/A TYR 289.A N ARG 285.A O no hydrogen 2.907 N/A ASN 291.A N LEU 288.A O no hydrogen 3.406 N/A ASN 291.A ND2 ASP 287.A O no hydrogen 2.501 N/A VAL 293.A N ILE 146.A O no hydrogen 3.240 N/A MET 294.A N ILE 325.A O no hydrogen 2.829 N/A SER 295.A N LEU 148.A O no hydrogen 3.182 N/A SER 295.A OG SER 136.A OG no hydrogen 3.293 N/A SER 295.A OG LEU 148.A O no hydrogen 3.224 N/A THR 298.A N SER 150.A O no hydrogen 2.925 N/A THR 298.A OG1 SER 150.A O no hydrogen 3.261 N/A THR 298.A OG1 SER 150.A OG no hydrogen 3.118 N/A THR 298.A OG1 GLY 151.A O no hydrogen 2.625 N/A THR 299.A OG1 SER 295.A O no hydrogen 3.098 N/A MET 300.A N THR 298.A O no hydrogen 2.770 N/A ILE 304.A N TYR 301.A O no hydrogen 3.292 N/A ARG 307.A NE GLU 311.A OE2 no hydrogen 3.168 N/A ARG 307.A NH1 ALA 215.A O no hydrogen 2.398 N/A ARG 307.A NH1 GLU 254.A OE2 no hydrogen 2.730 N/A ARG 307.A NH2 GLU 254.A OE2 no hydrogen 2.921 N/A ARG 307.A NH2 GLU 311.A OE2 no hydrogen 3.281 N/A MET 308.A N ILE 304.A O no hydrogen 2.994 N/A GLN 309.A N ALA 305.A O no hydrogen 2.895 N/A GLN 309.A NE2 ILE 322.A O no hydrogen 2.589 N/A LYS 310.A N ASP 306.A O no hydrogen 2.915 N/A GLU 311.A N ARG 307.A O no hydrogen 2.891 N/A ILE 312.A N MET 308.A O no hydrogen 2.917 N/A THR 313.A N GLN 309.A O no hydrogen 2.889 N/A THR 313.A OG1 GLN 309.A O no hydrogen 2.743 N/A ALA 314.A N LYS 310.A O no hydrogen 2.911 N/A LEU 315.A N GLU 311.A O no hydrogen 3.123 N/A ALA 316.A N THR 313.A O no hydrogen 3.066 N/A LYS 323.A N TYR 289.A O no hydrogen 3.217 N/A LYS 323.A NZ ILE 324.A O no hydrogen 2.787 N/A ILE 325.A N ASN 292.A O no hydrogen 2.686 N/A ARG 330.A NE PRO 327.A O no hydrogen 3.096 N/A TYR 332.A N GLU 329.A O no hydrogen 3.128 N/A SER 333.A OG GLU 329.A O no hydrogen 2.800 N/A SER 333.A OG GLU 329.A OE1 no hydrogen 3.548 N/A SER 333.A OG GLU 329.A OE2 no hydrogen 3.446 N/A ILE 336.A N TYR 332.A O no hydrogen 2.849 N/A GLY 337.A N SER 333.A O no hydrogen 2.898 N/A GLY 338.A N VAL 334.A O no hydrogen 2.898 N/A SER 339.A N TRP 335.A O no hydrogen 2.885 N/A SER 339.A OG TRP 335.A O no hydrogen 3.253 N/A SER 339.A OG ILE 336.A O no hydrogen 2.539 N/A ILE 340.A N ILE 336.A O no hydrogen 2.909 N/A LEU 341.A N GLY 337.A O no hydrogen 2.897 N/A ALA 342.A N GLY 338.A O no hydrogen 2.880 N/A SER 343.A N SER 339.A O no hydrogen 2.975 N/A SER 343.A OG SER 339.A O no hydrogen 2.489 N/A LEU 344.A N LEU 341.A O no hydrogen 3.197 N/A GLN 348.A NE2 ALA 342.A O no hydrogen 3.674 N/A GLN 349.A N THR 346.A O no hydrogen 3.290 N/A ILE 352.A N MET 127.A O no hydrogen 2.303 N/A LYS 354.A N PRO 125.A O no hydrogen 3.160 N/A LYS 354.A NZ ASP 358.A OD1 no hydrogen 3.145 N/A LYS 354.A NZ ASP 358.A OD2 no hydrogen 3.283 N/A GLN 355.A N GLN 355.A OE1 no hydrogen 2.603 N/A TYR 357.A N THR 353.A O no hydrogen 3.157 N/A ASP 358.A N LYS 354.A O no hydrogen 2.894 N/A ALA 360.A N GLU 356.A O no hydrogen 2.891 N/A GLY 361.A N TYR 357.A O no hydrogen 3.020 N/A ILE 364.A N GLY 361.A O no hydrogen 3.419 N/A HIS 366.A N SER 363.A O no hydrogen 2.972 N/A LYS 368.A N ILE 364.A O no hydrogen 3.169 N/A CYS 369.A SG VAL 129.A O no hydrogen 3.203 N/A