Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7t1h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N LEU 37.A O no hydrogen 2.964 N/A TYR 5.A N ASN 35.A O no hydrogen 3.019 N/A TYR 5.A OH GLU 114.A OE1 no hydrogen 2.991 N/A CYS 7.A N ASN 35.A OD1 no hydrogen 3.262 N/A CYS 7.A SG TYR 5.A O no hydrogen 3.533 N/A TYR 9.A OH SER 30.A OG no hydrogen 2.734 N/A GLY 10.A N ASP 8.A OD1 no hydrogen 3.247 N/A ASP 11.A N SER 341.A O no hydrogen 2.815 N/A ASN 12.A N TYR 9.A O no hydrogen 2.710 N/A THR 13.A N ASP 11.A OD1 no hydrogen 2.878 N/A THR 13.A OG1 ASP 11.A OD1 no hydrogen 2.542 N/A THR 13.A OG1 ASP 11.A OD2 no hydrogen 3.302 N/A PHE 14.A N MET 68.A O no hydrogen 2.745 N/A ASN 15.A ND2 SER 341.A OG no hydrogen 2.996 N/A LEU 16.A N HIS 70.A O no hydrogen 2.803 N/A ALA 17.A N VAL 28.A O no hydrogen 2.822 N/A ILE 18.A N ILE 72.A O no hydrogen 2.848 N/A ASP 19.A N LYS 26.A O no hydrogen 2.735 N/A ILE 20.A N THR 74.A O no hydrogen 2.812 N/A GLY 21.A N LEU 24.A O no hydrogen 2.760 N/A ALA 25.A N ILE 42.A O no hydrogen 2.751 N/A LYS 26.A N ASP 19.A O no hydrogen 2.796 N/A LYS 26.A NZ LEU 24.A O no hydrogen 2.958 N/A VAL 27.A N TYR 40.A O no hydrogen 2.745 N/A VAL 28.A N ALA 17.A O no hydrogen 2.989 N/A PHE 29.A N MET 38.A O no hydrogen 3.154 N/A SER 30.A OG TYR 9.A OH no hydrogen 2.734 N/A SER 30.A OG PRO 31.A O no hydrogen 3.560 N/A SER 30.A OG SER 34.A OG no hydrogen 3.034 N/A SER 30.A OG ARG 36.A O no hydrogen 2.392 N/A SER 34.A N PRO 31.A O no hydrogen 2.982 N/A SER 34.A OG TYR 9.A OH no hydrogen 3.359 N/A SER 34.A OG PRO 31.A O no hydrogen 2.781 N/A SER 34.A OG ARG 36.A O no hydrogen 3.264 N/A ASN 35.A N TYR 9.A OH no hydrogen 2.782 N/A ARG 36.A N SER 34.A OG no hydrogen 2.825 N/A ARG 36.A NH1 ASN 35.A O no hydrogen 2.995 N/A LEU 37.A N ILE 3.A O no hydrogen 2.776 N/A MET 38.A N PHE 29.A O no hydrogen 2.849 N/A PHE 39.A N GLN 1.A O no hydrogen 3.222 N/A TYR 40.A N VAL 27.A O no hydrogen 3.020 N/A THR 41.A OG1 TYR 327.A OH no hydrogen 2.522 N/A ILE 42.A N ALA 25.A O no hydrogen 2.908 N/A THR 44.A N THR 23.A O no hydrogen 3.054 N/A THR 44.A OG1 THR 23.A O no hydrogen 3.298 N/A LYS 49.A N LYS 46.A O no hydrogen 3.265 N/A PHE 50.A N LYS 46.A O no hydrogen 3.192 N/A MET 51.A N ILE 47.A O no hydrogen 2.872 N/A GLU 52.A N ASP 48.A O no hydrogen 2.876 N/A LEU 53.A N LYS 49.A O no hydrogen 3.136 N/A LEU 54.A N PHE 50.A O no hydrogen 3.404 N/A HIS 55.A N MET 51.A O no hydrogen 3.081 N/A HIS 55.A ND1 TYR 66.A OH no hydrogen 2.766 N/A SER 56.A N GLU 52.A O no hydrogen 2.863 N/A SER 56.A OG GLU 52.A O no hydrogen 2.970 N/A ILE 57.A N LEU 53.A O no hydrogen 2.837 N/A ILE 58.A N LEU 54.A O no hydrogen 3.048 N/A LYS 59.A N HIS 55.A O no hydrogen 2.936 N/A GLU 60.A N SER 56.A O no hydrogen 2.954 N/A HIS 61.A N ILE 57.A O no hydrogen 2.843 N/A ASN 62.A N ILE 58.A O no hydrogen 3.007 N/A ASN 62.A ND2 CYS 65.A O no hydrogen 2.973 N/A ASN 62.A ND2 THR 69.A OG1 no hydrogen 3.378 N/A GLY 64.A N ILE 58.A O no hydrogen 2.874 N/A CYS 65.A N ASN 62.A O no hydrogen 2.853 N/A TYR 66.A N GLY 64.A O no hydrogen 3.095 N/A TYR 66.A OH HIS 55.A ND1 no hydrogen 2.766 N/A ARG 67.A NE GLN 91.A O no hydrogen 3.317 N/A THR 69.A N TYR 66.A O no hydrogen 2.971 N/A THR 69.A OG1 CYS 65.A O no hydrogen 2.891 N/A HIS 70.A N PHE 14.A O no hydrogen 2.841 N/A HIS 70.A NE2 SER 96.A OG no hydrogen 2.725 N/A ILE 71.A N GLY 94.A O no hydrogen 2.943 N/A ILE 72.A N LEU 16.A O no hydrogen 3.060 N/A ALA 73.A N SER 96.A O no hydrogen 2.855 N/A THR 74.A N ILE 18.A O no hydrogen 2.759 N/A THR 74.A OG1 PHE 98.A O no hydrogen 2.516 N/A GLY 75.A N THR 74.A OG1 no hydrogen 2.917 N/A GLY 77.A N ILE 20.A O no hydrogen 3.001 N/A ALA 78.A N GLY 75.A O no hydrogen 2.894 N/A PHE 81.A N GLY 77.A O no hydrogen 3.140 N/A TYR 82.A N PHE 79.A O no hydrogen 3.404 N/A TYR 82.A OH ILE 95.A O no hydrogen 3.014 N/A LEU 85.A N PHE 81.A O no hydrogen 2.881 N/A TYR 86.A N TYR 82.A O no hydrogen 2.910 N/A GLU 87.A N ASP 83.A O no hydrogen 2.907 N/A ASN 88.A N LEU 84.A O no hydrogen 2.945 N/A ASN 88.A ND2 LEU 84.A O no hydrogen 3.047 N/A LYS 93.A N TYR 66.A O no hydrogen 3.259 N/A LYS 93.A N THR 69.A O no hydrogen 2.956 N/A SER 96.A N ILE 71.A O no hydrogen 3.005 N/A SER 96.A OG HIS 70.A NE2 no hydrogen 2.725 N/A PHE 98.A N ALA 73.A O no hydrogen 2.833 N/A MET 101.A N GLU 99.A OE2 no hydrogen 3.034 N/A GLU 102.A N GLU 99.A OE1 no hydrogen 2.937 N/A GLY 103.A N GLU 99.A O no hydrogen 2.954 N/A LEU 104.A N GLU 100.A O no hydrogen 2.957 N/A ILE 105.A N MET 101.A O no hydrogen 2.869 N/A HIS 106.A N GLU 102.A O no hydrogen 2.830 N/A GLY 107.A N GLY 103.A O no hydrogen 2.891 N/A LEU 108.A N LEU 104.A O no hydrogen 2.918 N/A ASP 109.A N ILE 105.A O no hydrogen 2.949 N/A PHE 110.A N HIS 106.A O no hydrogen 3.003 N/A PHE 111.A N GLY 107.A O no hydrogen 2.990 N/A ILE 112.A N LEU 108.A O no hydrogen 2.745 N/A HIS 113.A N ASP 109.A O no hydrogen 3.027 N/A HIS 113.A NE2 TYR 144.A OH no hydrogen 3.121 N/A GLU 114.A N PHE 110.A O no hydrogen 2.859 N/A ILE 115.A N PHE 111.A O no hydrogen 3.230 N/A PHE 120.A N PHE 321.A O no hydrogen 3.029 N/A THR 121.A N ARG 129.A O no hydrogen 2.940 N/A THR 121.A OG1 ARG 129.A O no hydrogen 3.450 N/A TYR 122.A OH ASP 124.A OD1 no hydrogen 2.665 N/A ASN 123.A ND2 ASP 126.A OD2 no hydrogen 3.186 N/A ASP 124.A N ASN 303.A OD1 no hydrogen 2.758 N/A ASP 126.A N ASN 123.A OD1 no hydrogen 2.627 N/A GLY 127.A N ASN 123.A O no hydrogen 2.858 N/A ARG 129.A N THR 121.A O no hydrogen 2.908 N/A ILE 131.A N VAL 119.A O no hydrogen 2.779 N/A THR 133.A N ILE 131.A O no hydrogen 2.864 N/A THR 133.A OG1 ILE 112.A O no hydrogen 2.514 N/A SER 135.A N PRO 132.A O no hydrogen 3.282 N/A TYR 144.A OH ASP 109.A OD2 no hydrogen 2.847 N/A TYR 146.A N VAL 160.A O no hydrogen 2.945 N/A TYR 146.A OH ASP 109.A OD1 no hydrogen 2.687 N/A LEU 147.A N ASN 287.A O no hydrogen 2.959 N/A LEU 148.A N LEU 158.A O no hydrogen 2.761 N/A VAL 149.A N TYR 289.A O no hydrogen 2.753 N/A ASN 150.A N SER 156.A O no hydrogen 2.715 N/A ILE 151.A N GLY 291.A O no hydrogen 2.817 N/A GLY 152.A N GLY 154.A O no hydrogen 2.798 N/A VAL 155.A N SER 172.A O no hydrogen 2.800 N/A SER 156.A N ASN 150.A O no hydrogen 2.917 N/A LEU 158.A N LEU 148.A O no hydrogen 2.906 N/A LYS 159.A N SER 167.A O no hydrogen 2.800 N/A LYS 159.A NZ ASN 283.A OD1 no hydrogen 3.064 N/A VAL 160.A N TYR 146.A O no hydrogen 2.768 N/A THR 161.A N ASN 165.A O no hydrogen 2.993 N/A THR 161.A OG1 ASN 165.A O no hydrogen 3.501 N/A ASN 165.A N GLU 162.A O no hydrogen 2.958 N/A ASN 165.A ND2 GLU 162.A OE2 no hydrogen 2.814 N/A SER 167.A N LYS 159.A O no hydrogen 2.975 N/A VAL 169.A N ILE 157.A O no hydrogen 2.883 N/A SER 172.A N VAL 155.A O no hydrogen 2.989 N/A LEU 174.A N SER 172.A OG no hydrogen 3.135 N/A GLY 175.A N THR 178.A OG1 no hydrogen 3.293 N/A GLY 177.A N SER 153.A O no hydrogen 2.873 N/A THR 178.A N GLY 175.A O no hydrogen 3.131 N/A THR 178.A OG1 SER 173.A O no hydrogen 3.015 N/A LEU 179.A N GLY 175.A O no hydrogen 3.313 N/A TRP 180.A N GLY 176.A O no hydrogen 2.853 N/A GLY 181.A N GLY 177.A O no hydrogen 2.847 N/A LEU 182.A N THR 178.A O no hydrogen 2.986 N/A LEU 183.A N LEU 179.A O no hydrogen 3.001 N/A SER 184.A N TRP 180.A O no hydrogen 2.923 N/A SER 184.A OG TRP 180.A O no hydrogen 2.992 N/A SER 184.A OG GLY 181.A O no hydrogen 3.107 N/A LEU 185.A N GLY 181.A O no hydrogen 3.222 N/A ILE 186.A N LEU 182.A O no hydrogen 2.920 N/A THR 187.A N LEU 183.A O no hydrogen 2.839 N/A THR 187.A OG1 LEU 183.A O no hydrogen 2.444 N/A GLY 188.A N SER 184.A O no hydrogen 2.913 N/A ALA 189.A N THR 187.A OG1 no hydrogen 3.137 N/A GLN 190.A N GLN 194.A OE1 no hydrogen 2.820 N/A TYR 192.A OH TYR 294.A O no hydrogen 2.860 N/A GLN 194.A N THR 191.A OG1 no hydrogen 2.957 N/A MET 195.A N THR 191.A O no hydrogen 3.195 N/A LEU 196.A N TYR 192.A O no hydrogen 3.044 N/A ASP 197.A N ASP 193.A O no hydrogen 3.024 N/A TRP 198.A N GLN 194.A O no hydrogen 2.857 N/A ALA 199.A N MET 195.A O no hydrogen 2.954 N/A GLN 200.A N LEU 196.A O no hydrogen 2.993 N/A GLN 200.A N ASP 197.A O no hydrogen 3.030 N/A GLY 202.A N ALA 199.A O no hydrogen 3.081 N/A ASP 203.A N ASP 259.A OD1 no hydrogen 2.626 N/A ASN 204.A ND2 ASP 208.A OD2 no hydrogen 2.803 N/A SER 205.A N ASP 203.A OD1 no hydrogen 3.195 N/A SER 205.A OG ASP 203.A OD1 no hydrogen 2.982 N/A SER 205.A OG ASP 203.A OD2 no hydrogen 3.273 N/A SER 206.A N ASP 203.A O no hydrogen 3.320 N/A SER 206.A OG ASP 203.A O no hydrogen 3.533 N/A SER 206.A OG ASP 259.A OD2 no hydrogen 2.930 N/A VAL 207.A N ASN 204.A O no hydrogen 2.891 N/A ASP 208.A N ASN 204.A O no hydrogen 2.827 N/A MET 209.A N SER 229.A O no hydrogen 2.911 N/A LEU 210.A N ASP 213.A OD2 no hydrogen 2.774 N/A VAL 211.A N ALA 226.A O no hydrogen 2.946 N/A GLY 212.A N SER 224.A O no hydrogen 2.773 N/A ILE 214.A N LEU 210.A O no hydrogen 3.358 N/A ILE 214.A N VAL 211.A O no hydrogen 3.021 N/A TYR 215.A N VAL 211.A O no hydrogen 2.722 N/A TYR 219.A N LEU 222.A O no hydrogen 3.207 N/A SER 224.A N ASP 218.A OD1 no hydrogen 2.849 N/A SER 224.A OG.B ASP 218.A OD1 no hydrogen 3.530 N/A SER 224.A OG.C ASP 218.A OD1 no hydrogen 2.849 N/A ALA 226.A N LYS 223.A O no hydrogen 3.083 N/A ALA 228.A N MET 209.A O no hydrogen 2.825 N/A SER 229.A N MET 209.A O no hydrogen 2.958 N/A PHE 231.A N ASP 208.A OD1 no hydrogen 2.901 N/A GLY 232.A N SER 229.A O no hydrogen 3.117 N/A LYS 233.A N VAL 207.A O no hydrogen 2.858 N/A LYS 233.A NZ SER 205.A O no hydrogen 2.536 N/A LYS 233.A NZ ASP 208.A O no hydrogen 3.054 N/A LYS 233.A NZ ASP 213.A OD1 no hydrogen 3.548 N/A LYS 233.A NZ ASP 213.A OD2 no hydrogen 2.942 N/A VAL 234.A N PHE 231.A O no hydrogen 3.084 N/A SER 243.A N SER 246.A OG no hydrogen 2.883 N/A SER 246.A N SER 243.A OG no hydrogen 3.026 N/A SER 246.A OG SER 243.A O no hydrogen 2.893 N/A ILE 247.A N SER 243.A O no hydrogen 3.028 N/A GLU 248.A N HIS 244.A O no hydrogen 2.807 N/A LYS 249.A N GLU 245.A O no hydrogen 2.930 N/A ASN 250.A N SER 246.A O no hydrogen 3.061 N/A ASN 251.A N ILE 247.A O no hydrogen 3.103 N/A ASN 251.A ND2 ILE 247.A O no hydrogen 2.788 N/A MET 254.A N ASN 251.A O no hydrogen 3.011 N/A ILE 260.A N LYS 256.A O no hydrogen 3.096 N/A CYS 261.A N ASN 257.A O no hydrogen 2.931 N/A CYS 261.A SG ASN 257.A O no hydrogen 3.378 N/A LYS 262.A N PRO 258.A O no hydrogen 3.034 N/A LYS 262.A NZ GLY 202.A O no hydrogen 3.282 N/A SER 263.A N ASP 259.A O no hydrogen 2.999 N/A SER 263.A OG ASP 208.A OD1 no hydrogen 2.505 N/A SER 263.A OG ASP 208.A OD2 no hydrogen 3.561 N/A LEU 264.A N ILE 260.A O no hydrogen 3.067 N/A LEU 265.A N CYS 261.A O no hydrogen 2.956 N/A PHE 266.A N LYS 262.A O no hydrogen 2.950 N/A ALA 267.A N SER 263.A O no hydrogen 2.841 N/A ILE 268.A N LEU 264.A O no hydrogen 2.948 N/A SER 269.A N LEU 265.A O no hydrogen 3.005 N/A SER 269.A OG LEU 265.A O no hydrogen 2.888 N/A SER 269.A OG TYR 294.A OH no hydrogen 2.738 N/A ASN 270.A N PHE 266.A O no hydrogen 2.840 N/A ASN 271.A N ALA 267.A O no hydrogen 3.072 N/A ILE 272.A N ILE 268.A O no hydrogen 3.003 N/A GLY 273.A N SER 269.A O no hydrogen 2.894 N/A GLN 274.A N ASN 270.A O no hydrogen 2.951 N/A ILE 275.A N ASN 271.A O no hydrogen 3.053 N/A ALA 276.A N ILE 272.A O no hydrogen 2.916 N/A TYR 277.A N GLY 273.A O no hydrogen 2.936 N/A LEU 278.A N GLN 274.A O no hydrogen 2.878 N/A GLN 279.A N ILE 275.A O no hydrogen 2.947 N/A GLN 279.A NE2 GLY 170.A O no hydrogen 2.855 N/A ALA 280.A N ALA 276.A O no hydrogen 2.896 N/A LYS 281.A N TYR 277.A O no hydrogen 2.787 N/A ILE 282.A N LEU 278.A O no hydrogen 3.023 N/A ASN 283.A N GLN 279.A O no hydrogen 3.124 N/A ASN 283.A ND2 GLN 279.A O no hydrogen 2.787 N/A ASN 284.A N LYS 281.A O no hydrogen 3.197 N/A ILE 285.A N ALA 280.A O no hydrogen 2.818 N/A GLN 286.A NE2 ASN 284.A OD1 no hydrogen 3.206 N/A ASN 287.A ND2 ALA 142.A O no hydrogen 3.130 N/A ASN 287.A ND2 ILE 143.A O no hydrogen 3.205 N/A ASN 287.A ND2 PRO 145.A O no hydrogen 3.465 N/A ILE 288.A N GLN 318.A O no hydrogen 2.894 N/A TYR 289.A N LEU 147.A O no hydrogen 2.689 N/A PHE 290.A N PHE 320.A O no hydrogen 2.924 N/A GLY 291.A N VAL 149.A O no hydrogen 2.851 N/A GLY 292.A N GLU 325.A O no hydrogen 2.939 N/A SER 293.A N ILE 151.A O no hydrogen 3.181 N/A TYR 294.A OH SER 269.A OG no hydrogen 2.738 N/A THR 295.A OG1 GLU 325.A OE1 no hydrogen 2.457 N/A ARG 296.A N GLU 325.A OE2 no hydrogen 2.780 N/A ARG 296.A NE SER 293.A O no hydrogen 2.840 N/A ARG 296.A NH2 SER 293.A O no hydrogen 3.483 N/A HIS 298.A N THR 295.A O no hydrogen 2.851 N/A THR 300.A OG1 GLN 200.A OE1 no hydrogen 2.988 N/A MET 302.A N HIS 298.A O no hydrogen 3.036 N/A ASN 303.A N LEU 299.A O no hydrogen 2.779 N/A THR 304.A N THR 300.A O no hydrogen 2.814 N/A THR 304.A OG1 THR 300.A O no hydrogen 2.821 N/A LEU 305.A N THR 301.A O no hydrogen 2.914 N/A SER 306.A N MET 302.A O no hydrogen 2.910 N/A SER 306.A OG TYR 122.A O no hydrogen 2.797 N/A SER 306.A OG MET 302.A O no hydrogen 2.880 N/A TYR 307.A N ASN 303.A O no hydrogen 2.958 N/A ALA 308.A N THR 304.A O no hydrogen 3.078 N/A ILE 309.A N LEU 305.A O no hydrogen 3.115 N/A ASN 310.A N SER 306.A O no hydrogen 2.832 N/A PHE 311.A N TYR 307.A O no hydrogen 2.614 N/A TRP 312.A N ALA 308.A O no hydrogen 2.984 N/A SER 313.A N ILE 309.A O no hydrogen 3.263 N/A SER 313.A OG ILE 309.A O no hydrogen 2.882 N/A SER 313.A OG ASN 310.A O no hydrogen 3.517 N/A SER 313.A OG LYS 317.A O no hydrogen 3.566 N/A GLN 314.A N PHE 311.A O no hydrogen 3.255 N/A GLY 315.A N ASN 310.A O no hydrogen 2.901 N/A SER 316.A N SER 313.A O no hydrogen 3.008 N/A SER 316.A OG SER 313.A O no hydrogen 2.888 N/A LYS 317.A N SER 313.A OG no hydrogen 2.933 N/A LYS 317.A NZ ILE 285.A O no hydrogen 2.819 N/A GLN 318.A N GLN 286.A O no hydrogen 2.853 N/A GLN 318.A NE2 ALA 319.A O no hydrogen 3.083 N/A PHE 320.A N ILE 288.A O no hydrogen 2.734 N/A PHE 321.A N PHE 120.A O no hydrogen 2.691 N/A LYS 323.A N GLU 118.A O no hydrogen 2.870 N/A LYS 323.A NZ GLU 128.A OE1 no hydrogen 2.900 N/A HIS 324.A N GLU 118.A OE1 no hydrogen 2.713 N/A HIS 324.A ND1 GLU 118.A OE2 no hydrogen 2.570 N/A GLU 325.A N LEU 322.A O no hydrogen 3.174 N/A TYR 327.A N HIS 324.A O no hydrogen 2.947 N/A MET 331.A N TYR 327.A O no hydrogen 2.770 N/A GLY 332.A N LEU 328.A O no hydrogen 3.048 N/A ALA 333.A N GLY 329.A O no hydrogen 2.977 N/A PHE 334.A N ALA 330.A O no hydrogen 2.856 N/A LEU 335.A N MET 331.A O no hydrogen 3.045 N/A SER 336.A N GLY 332.A O no hydrogen 3.162 N/A ALA 337.A N ALA 333.A O no hydrogen 3.095 N/A SER 338.A N PHE 334.A O no hydrogen 2.751 N/A SER 338.A OG ASP 8.A O no hydrogen 3.295 N/A ARG 339.A N LEU 335.A O no hydrogen 3.015 N/A HIS 340.A N SER 336.A O no hydrogen 3.035 N/A SER 341.A N ALA 337.A O no hydrogen 2.921 N/A SER 341.A OG ALA 337.A O no hydrogen 3.193 N/A SER 341.A OG SER 338.A O no hydrogen 3.073 N/A SER 342.A OG ASP 8.A OD2 no hydrogen 2.578 N/A