Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7t4j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 7.A N ILE 75.A O no hydrogen 2.679 N/A LYS 8.A N GLU 11.A OE1 no hydrogen 2.627 N/A LYS 8.A NZ GLU 34.A OE1 no hydrogen 3.276 N/A LYS 8.A NZ GLU 34.A OE2 no hydrogen 3.472 N/A GLU 11.A N LYS 8.A O no hydrogen 2.835 N/A LYS 13.A N LEU 30.A O no hydrogen 2.892 N/A LYS 14.A NZ GLU 46.A OE1 no hydrogen 2.734 N/A ILE 15.A N LYS 28.A O no hydrogen 2.890 N/A LYS 16.A N LYS 28.A O no hydrogen 3.321 N/A LEU 18.A N VAL 26.A O no hydrogen 2.882 N/A GLY 19.A N VAL 26.A O no hydrogen 3.380 N/A GLY 21.A N GLY 24.A O no hydrogen 3.036 N/A THR 25.A N GLU 46.A O no hydrogen 2.762 N/A VAL 26.A N GLY 19.A O no hydrogen 2.881 N/A TYR 27.A N ILE 44.A O no hydrogen 2.811 N/A TYR 27.A OH GLU 46.A OE2 no hydrogen 3.107 N/A LYS 28.A N LYS 16.A O no hydrogen 2.803 N/A GLY 29.A N VAL 42.A O no hydrogen 2.752 N/A LEU 30.A N LYS 13.A O no hydrogen 2.903 N/A TRP 31.A N ILE 40.A O no hydrogen 2.913 N/A TRP 31.A NE1 GLU 11.A OE2 no hydrogen 2.993 N/A ILE 32.A N GLU 11.A O no hydrogen 2.987 N/A GLU 34.A N GLU 11.A OE2 no hydrogen 3.384 N/A GLU 36.A N PRO 33.A O no hydrogen 3.040 N/A ILE 40.A N TRP 31.A O no hydrogen 2.733 N/A VAL 42.A N GLY 29.A O no hydrogen 2.995 N/A ALA 43.A N THR 85.A O no hydrogen 3.065 N/A ILE 44.A N TYR 27.A O no hydrogen 2.862 N/A LYS 45.A N LEU 83.A O no hydrogen 2.792 N/A LYS 45.A NZ GLU 54.A OE1 no hydrogen 3.320 N/A LYS 45.A NZ GLU 54.A OE2 no hydrogen 2.568 N/A GLU 46.A N THR 25.A O no hydrogen 3.087 N/A LYS 49.A NZ ASP 53.A OD2 no hydrogen 3.078 N/A ILE 51.A N ASN 48.A O no hydrogen 3.317 N/A LEU 52.A N LYS 49.A O no hydrogen 3.033 N/A ASP 53.A N LYS 49.A O no hydrogen 2.983 N/A GLU 54.A N GLU 50.A O no hydrogen 2.986 N/A ALA 55.A N ILE 51.A O no hydrogen 3.032 N/A TYR 56.A N LEU 52.A O no hydrogen 2.890 N/A VAL 57.A N ASP 53.A O no hydrogen 2.943 N/A MET 58.A N GLU 54.A O no hydrogen 2.962 N/A ALA 59.A N ALA 55.A O no hydrogen 3.004 N/A ALA 59.A N TYR 56.A O no hydrogen 3.053 N/A SER 60.A N TYR 56.A O no hydrogen 2.821 N/A SER 60.A OG TYR 56.A O no hydrogen 2.972 N/A ASP 62.A N ALA 59.A O no hydrogen 3.058 N/A GLY 65.A N TYR 122.A OH no hydrogen 2.690 N/A HIS 68.A N ASN 66.A OD1 no hydrogen 2.648 N/A HIS 68.A ND1 VAL 146.A O no hydrogen 2.954 N/A VAL 69.A N ASN 66.A O no hydrogen 3.143 N/A CYS 70.A N ILE 148.A O no hydrogen 2.955 N/A CYS 70.A SG ARG 71.A O no hydrogen 3.895 N/A CYS 70.A SG GLN 86.A O no hydrogen 3.771 N/A ARG 71.A N GLN 86.A OE1 no hydrogen 2.745 N/A LEU 73.A N ILE 84.A O no hydrogen 2.828 N/A GLY 74.A N ILE 84.A O no hydrogen 3.227 N/A ILE 75.A N ARG 5.A O no hydrogen 2.945 N/A CYS 76.A N GLN 82.A O no hydrogen 3.090 N/A CYS 76.A SG LEU 7.A O no hydrogen 3.544 N/A CYS 76.A SG GLN 82.A OE1 no hydrogen 3.649 N/A THR 78.A OG1 GLN 82.A OE1 no hydrogen 3.215 N/A THR 80.A OG1 VAL 81.A O no hydrogen 3.148 N/A GLN 82.A N CYS 76.A O no hydrogen 3.045 N/A LEU 83.A N LYS 45.A O no hydrogen 2.950 N/A ILE 84.A N GLY 74.A O no hydrogen 2.996 N/A THR 85.A N ALA 43.A O no hydrogen 2.957 N/A GLN 86.A N ARG 71.A O no hydrogen 3.122 N/A PHE 90.A N VAL 140.A O no hydrogen 3.127 N/A GLY 91.A N MET 88.A O no hydrogen 3.283 N/A LEU 93.A N VAL 138.A O no hydrogen 2.709 N/A LEU 94.A N ALA 135.A O no hydrogen 3.066 N/A TYR 96.A N CYS 92.A O no hydrogen 3.094 N/A VAL 97.A N LEU 93.A O no hydrogen 2.890 N/A ARG 98.A N LEU 94.A O no hydrogen 3.274 N/A ARG 98.A NE GLY 206.A O no hydrogen 2.882 N/A ARG 98.A NH2 GLY 206.A O no hydrogen 3.246 N/A GLU 99.A N ASP 95.A O no hydrogen 3.062 N/A HIS 100.A N TYR 96.A O no hydrogen 3.060 N/A ASN 103.A N HIS 100.A O no hydrogen 2.672 N/A SER 106.A N ASP 279.A OD2 no hydrogen 3.356 N/A SER 106.A OG ASP 279.A OD2 no hydrogen 3.175 N/A GLN 107.A NE2 GLN 107.A O no hydrogen 3.520 N/A GLN 107.A NE2 ALA 267.A O no hydrogen 3.059 N/A TYR 108.A N GLY 105.A O no hydrogen 3.221 N/A LEU 109.A N GLY 105.A O no hydrogen 3.424 N/A LEU 110.A N SER 106.A O no hydrogen 3.284 N/A ASN 111.A N GLN 107.A O no hydrogen 2.964 N/A TRP 112.A N TYR 108.A O no hydrogen 2.917 N/A TRP 112.A NE1 PRO 143.A O no hydrogen 2.849 N/A CYS 113.A N LEU 109.A O no hydrogen 3.370 N/A CYS 113.A SG LEU 109.A O no hydrogen 3.073 N/A VAL 114.A N LEU 110.A O no hydrogen 3.028 N/A VAL 114.A N ASN 111.A O no hydrogen 3.104 N/A GLN 115.A N ASN 111.A O no hydrogen 3.115 N/A GLN 115.A NE2 GLN 144.A O no hydrogen 2.968 N/A ILE 116.A N TRP 112.A O no hydrogen 2.895 N/A ALA 117.A N CYS 113.A O no hydrogen 3.285 N/A LYS 118.A N VAL 114.A O no hydrogen 2.742 N/A GLY 119.A N GLN 115.A O no hydrogen 2.836 N/A MET 120.A N ILE 116.A O no hydrogen 3.009 N/A ASN 121.A N ALA 117.A O no hydrogen 2.815 N/A TYR 122.A N LYS 118.A O no hydrogen 3.098 N/A TYR 122.A OH VAL 61.A O no hydrogen 2.580 N/A LEU 123.A N GLY 119.A O no hydrogen 3.009 N/A GLU 124.A N MET 120.A O no hydrogen 2.995 N/A ASP 125.A N ASN 121.A O no hydrogen 2.848 N/A ARG 126.A N TYR 122.A O no hydrogen 2.859 N/A ARG 126.A N LEU 123.A O no hydrogen 2.964 N/A ARG 127.A N GLU 124.A O no hydrogen 2.927 N/A ARG 127.A NE LEU 157.A O no hydrogen 3.080 N/A ARG 127.A NH2 GLY 158.A O no hydrogen 2.631 N/A LEU 128.A N LEU 123.A O no hydrogen 2.764 N/A VAL 129.A N LYS 155.A O no hydrogen 2.877 N/A HIS 130.A N ASP 191.A OD2 no hydrogen 2.670 N/A HIS 130.A NE2 THR 149.A O no hydrogen 2.942 N/A ARG 131.A N ASP 191.A OD1 no hydrogen 2.878 N/A ARG 131.A NH1 LEU 153.A O no hydrogen 2.668 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 2.923 N/A ALA 135.A N GLU 201.A OE1 no hydrogen 3.228 N/A ARG 136.A NH2 ASP 132.A OD1 no hydrogen 3.263 N/A ASN 137.A N ALA 134.A O no hydrogen 2.868 N/A ASN 137.A ND2 ASP 132.A O no hydrogen 3.149 N/A VAL 138.A N ALA 135.A O no hydrogen 3.351 N/A LEU 139.A N LYS 147.A O no hydrogen 2.813 N/A VAL 140.A N GLY 91.A O no hydrogen 2.921 N/A LYS 141.A N HIS 145.A O no hydrogen 2.854 N/A THR 142.A N HIS 145.A O no hydrogen 3.223 N/A THR 142.A OG1 GLN 144.A OE1 no hydrogen 3.093 N/A GLN 144.A N THR 142.A OG1 no hydrogen 3.281 N/A GLN 144.A NE2 TYR 108.A OH no hydrogen 2.804 N/A HIS 145.A N THR 142.A O no hydrogen 2.673 N/A HIS 145.A NE2 PRO 67.A O no hydrogen 2.866 N/A VAL 146.A N GLN 115.A OE1 no hydrogen 2.819 N/A LYS 147.A N LEU 139.A O no hydrogen 2.856 N/A LYS 147.A NZ GLN 86.A OE1 no hydrogen 2.982 N/A ILE 148.A N HIS 68.A O no hydrogen 2.700 N/A THR 149.A N ASN 137.A O no hydrogen 2.958 N/A GLY 152.A N ASP 150.A OD1 no hydrogen 3.087 N/A ALA 154.A N PHE 151.A O no hydrogen 2.992 N/A LYS 155.A N VAL 129.A O no hydrogen 2.930 N/A LYS 155.A NZ TYR 164.A OH no hydrogen 3.392 N/A LEU 157.A N ARG 127.A O no hydrogen 2.890 N/A GLY 158.A N GLU 161.A OE1 no hydrogen 2.828 N/A GLU 161.A N GLY 158.A O no hydrogen 3.204 N/A TYR 164.A N TYR 186.A O no hydrogen 2.888 N/A HIS 165.A ND1 ALA 166.A O no hydrogen 3.260 N/A ALA 166.A N ARG 184.A O no hydrogen 3.079 N/A LYS 174.A NZ TYR 210.A O no hydrogen 3.090 N/A LYS 174.A NZ ILE 213.A O no hydrogen 2.763 N/A TRP 175.A NE1 GLU 201.A OE1 no hydrogen 2.572 N/A MET 176.A N ILE 173.A O no hydrogen 2.597 N/A GLU 179.A N GLU 179.A OE1 no hydrogen 2.548 N/A SER 180.A N ALA 177.A O no hydrogen 2.815 N/A SER 180.A OG ILE 185.A O no hydrogen 2.496 N/A ILE 181.A N ALA 177.A O no hydrogen 2.991 N/A LEU 182.A N LEU 178.A O no hydrogen 2.891 N/A HIS 183.A N GLU 179.A O no hydrogen 2.981 N/A ARG 184.A N SER 180.A O no hydrogen 2.983 N/A ILE 185.A N GLU 179.A O no hydrogen 3.423 N/A TYR 186.A N TYR 164.A O no hydrogen 3.179 N/A THR 187.A N SER 190.A OG no hydrogen 2.678 N/A GLN 189.A NE2 ALA 250.A O no hydrogen 3.560 N/A GLN 189.A NE2 PRO 254.A O no hydrogen 3.115 N/A SER 190.A N THR 187.A OG1 no hydrogen 2.978 N/A SER 190.A OG THR 187.A O no hydrogen 2.642 N/A ASP 191.A N THR 187.A O no hydrogen 3.296 N/A VAL 192.A N HIS 188.A O no hydrogen 3.097 N/A TRP 193.A N GLN 189.A O no hydrogen 3.270 N/A SER 194.A N SER 190.A O no hydrogen 3.304 N/A SER 194.A OG TRP 175.A O no hydrogen 2.959 N/A SER 194.A OG SER 190.A O no hydrogen 3.362 N/A TYR 195.A N ASP 191.A O no hydrogen 2.850 N/A TYR 195.A OH CYS 113.A O no hydrogen 2.603 N/A GLY 196.A N VAL 192.A O no hydrogen 2.930 N/A VAL 197.A N TRP 193.A O no hydrogen 3.231 N/A THR 198.A N TYR 195.A O no hydrogen 3.007 N/A THR 198.A OG1 SER 194.A O no hydrogen 2.759 N/A VAL 199.A N TYR 195.A O no hydrogen 2.960 N/A TRP 200.A N GLY 196.A O no hydrogen 2.917 N/A TRP 200.A NE1 PRO 229.A O no hydrogen 2.893 N/A GLU 201.A N VAL 197.A O no hydrogen 2.936 N/A LEU 202.A N THR 198.A O no hydrogen 3.036 N/A MET 203.A N VAL 199.A O no hydrogen 2.879 N/A THR 204.A N TRP 200.A O no hydrogen 3.074 N/A THR 204.A OG1 TRP 200.A O no hydrogen 3.097 N/A THR 204.A OG1 GLU 201.A O no hydrogen 3.360 N/A PHE 205.A N LEU 202.A O no hydrogen 3.051 N/A GLY 206.A N GLU 201.A O no hydrogen 2.755 N/A SER 207.A N THR 204.A OG1 no hydrogen 3.107 N/A SER 207.A OG THR 204.A O no hydrogen 3.249 N/A ILE 213.A N TYR 210.A O no hydrogen 3.181 N/A GLU 217.A N PRO 214.A O no hydrogen 3.162 N/A ILE 221.A N GLU 217.A O no hydrogen 2.765 N/A LEU 222.A N ILE 218.A O no hydrogen 2.713 N/A GLU 223.A N SER 219.A O no hydrogen 2.885 N/A LYS 224.A N SER 220.A O no hydrogen 3.042 N/A GLY 225.A N LEU 222.A O no hydrogen 3.097 N/A GLU 226.A N ILE 221.A O no hydrogen 3.057 N/A ARG 227.A NE TRP 246.A O no hydrogen 2.980 N/A ARG 227.A NH1 TRP 246.A O no hydrogen 2.992 N/A ARG 227.A NH2 LEU 222.A O no hydrogen 2.714 N/A ARG 227.A NH2 GLU 226.A O no hydrogen 2.950 N/A CYS 234.A N PRO 231.A O no hydrogen 3.000 N/A THR 235.A N TYR 273.A O no hydrogen 3.193 N/A THR 235.A OG1 TYR 273.A O no hydrogen 2.675 N/A VAL 238.A N THR 235.A O no hydrogen 3.126 N/A TYR 239.A N THR 235.A O no hydrogen 3.250 N/A TYR 239.A OH LEU 228.A O no hydrogen 2.894 N/A MET 240.A N ILE 236.A O no hydrogen 3.031 N/A ILE 241.A N ASP 237.A O no hydrogen 3.468 N/A MET 242.A N VAL 238.A O no hydrogen 3.405 N/A ARG 243.A N TYR 239.A O no hydrogen 3.089 N/A ARG 243.A NH2 TYR 239.A OH no hydrogen 2.925 N/A LYS 244.A N MET 240.A O no hydrogen 2.806 N/A CYS 245.A N ILE 241.A O no hydrogen 3.054 N/A CYS 245.A N MET 242.A O no hydrogen 2.726 N/A CYS 245.A SG ILE 241.A O no hydrogen 3.432 N/A TRP 246.A N ARG 243.A O no hydrogen 3.065 N/A MET 247.A N LYS 244.A O no hydrogen 3.274 N/A SER 252.A N ASP 249.A O no hydrogen 2.985 N/A SER 252.A OG ASP 249.A O no hydrogen 3.534 N/A SER 252.A OG ASP 249.A OD2 no hydrogen 2.378 N/A ARG 253.A N ALA 250.A O no hydrogen 2.946 N/A ARG 253.A NE MET 247.A O no hydrogen 2.867 N/A ARG 253.A NH1 GLU 179.A OE2 no hydrogen 3.012 N/A ARG 253.A NH1 GLN 189.A O no hydrogen 3.092 N/A ARG 253.A NH2 GLU 179.A OE1 no hydrogen 2.866 N/A ARG 253.A NH2 GLU 179.A OE2 no hydrogen 3.401 N/A ARG 253.A NH2 MET 247.A O no hydrogen 3.152 N/A LYS 255.A N GLU 258.A OE1 no hydrogen 2.954 N/A GLU 258.A N LYS 255.A O no hydrogen 2.610 N/A LEU 259.A N LYS 255.A O no hydrogen 2.997 N/A ILE 260.A N PHE 256.A O no hydrogen 2.998 N/A GLU 262.A N GLU 258.A O no hydrogen 2.793 N/A PHE 263.A N LEU 259.A O no hydrogen 2.881 N/A SER 264.A N ILE 260.A O no hydrogen 2.895 N/A SER 264.A OG ILE 260.A O no hydrogen 2.565 N/A LYS 265.A N ILE 261.A O no hydrogen 2.947 N/A MET 266.A N GLU 262.A O no hydrogen 3.055 N/A ALA 267.A N PHE 263.A O no hydrogen 2.715 N/A ARG 268.A N SER 264.A O no hydrogen 3.004 N/A ARG 268.A N LYS 265.A O no hydrogen 3.017 N/A ASP 269.A N MET 266.A O no hydrogen 2.853 N/A ARG 272.A N ASP 269.A O no hydrogen 3.192 N/A TYR 273.A N PRO 270.A O no hydrogen 2.746 N/A LEU 274.A N PRO 270.A O no hydrogen 2.800 N/A VAL 275.A N ILE 233.A O no hydrogen 2.839 N/A ASP 279.A N ILE 276.A O no hydrogen 3.513 N/A