Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7ti2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 5.A N ALA 1.A O no hydrogen 2.856 N/A LYS 6.A N GLU 2.A O no hydrogen 2.898 N/A LEU 7.A N PRO 3.A O no hydrogen 3.013 N/A GLU 8.A N PHE 4.A O no hydrogen 2.999 N/A GLN 9.A N ALA 5.A O no hydrogen 3.026 N/A ASP 10.A N LYS 6.A O no hydrogen 2.931 N/A PHE 11.A N LEU 7.A O no hydrogen 2.940 N/A GLY 12.A N GLU 8.A O no hydrogen 2.838 N/A GLY 13.A N GLU 8.A O no hydrogen 3.176 N/A SER 14.A N ARG 235.A O no hydrogen 2.775 N/A ILE 15.A N GLU 8.A OE1 no hydrogen 3.004 N/A GLY 16.A N TYR 233.A O no hydrogen 2.697 N/A VAL 17.A N TYR 30.A O no hydrogen 2.796 N/A TYR 18.A N ALA 231.A O no hydrogen 3.136 N/A ALA 19.A N VAL 28.A O no hydrogen 2.980 N/A MET 20.A N VAL 229.A O no hydrogen 2.747 N/A ASP 21.A N ALA 26.A O no hydrogen 2.875 N/A THR 22.A N PRO 227.A O no hydrogen 3.073 N/A THR 22.A OG1 PRO 227.A O no hydrogen 2.726 N/A GLY 23.A N ASP 21.A OD1 no hydrogen 2.838 N/A SER 24.A N ASP 21.A OD1 no hydrogen 3.243 N/A GLY 25.A N ASP 21.A O no hydrogen 2.787 N/A ALA 26.A N SER 24.A OG no hydrogen 3.030 N/A VAL 28.A N ALA 19.A O no hydrogen 2.965 N/A TYR 30.A N VAL 17.A O no hydrogen 2.902 N/A TYR 30.A OH GLU 8.A OE2 no hydrogen 2.506 N/A ARG 31.A NE GLU 8.A OE1 no hydrogen 2.952 N/A ARG 31.A NE GLU 8.A OE2 no hydrogen 3.361 N/A ARG 31.A NH1 GLU 34.A OE2 no hydrogen 2.818 N/A ARG 31.A NH2 GLU 8.A OE2 no hydrogen 2.913 N/A GLU 34.A N ARG 31.A O no hydrogen 3.159 N/A ARG 35.A NH1 THR 129.A O no hydrogen 2.997 N/A ARG 35.A NH1 THR 150.A OG1 no hydrogen 2.889 N/A ARG 35.A NH2 THR 129.A O no hydrogen 3.034 N/A PHE 36.A N SER 151.A O no hydrogen 2.889 N/A LEU 38.A N ASP 149.A O no hydrogen 2.947 N/A CYS 39.A SG PRO 37.A O no hydrogen 4.015 N/A CYS 39.A SG THR 213.A O no hydrogen 3.933 N/A SER 40.A OG SER 100.A OG no hydrogen 3.071 N/A SER 41.A N LEU 38.A O no hydrogen 3.029 N/A SER 41.A OG LEU 38.A O no hydrogen 2.639 N/A SER 41.A OG TYR 233.A OH no hydrogen 2.892 N/A LYS 43.A N SER 40.A O no hydrogen 2.893 N/A LYS 43.A NZ SER 40.A OG no hydrogen 2.913 N/A LYS 43.A NZ SER 100.A O no hydrogen 2.759 N/A LYS 43.A NZ SER 100.A OG no hydrogen 3.290 N/A LYS 43.A NZ ASN 102.A OD1 no hydrogen 2.685 N/A LEU 46.A N PHE 42.A O no hydrogen 2.886 N/A ALA 47.A N LYS 43.A O no hydrogen 3.082 N/A ALA 48.A N GLY 44.A O no hydrogen 3.103 N/A ALA 49.A N PHE 45.A O no hydrogen 2.884 N/A VAL 50.A N LEU 46.A O no hydrogen 3.026 N/A LEU 51.A N ALA 47.A O no hydrogen 2.955 N/A ALA 52.A N ALA 48.A O no hydrogen 2.842 N/A ARG 53.A N ALA 49.A O no hydrogen 3.003 N/A SER 54.A N VAL 50.A O no hydrogen 2.952 N/A SER 54.A OG LEU 51.A O no hydrogen 2.513 N/A GLN 55.A N LEU 51.A O no hydrogen 3.284 N/A GLN 55.A N ALA 52.A O no hydrogen 3.201 N/A GLN 56.A N ARG 53.A O no hydrogen 2.981 N/A GLN 57.A N ARG 53.A O no hydrogen 3.110 N/A LEU 60.A N GLN 57.A O no hydrogen 3.190 N/A THR 63.A N LEU 60.A O no hydrogen 3.075 N/A THR 63.A OG1 GLY 59.A O no hydrogen 2.748 N/A THR 63.A OG1 LEU 60.A O no hydrogen 3.367 N/A ILE 65.A N MET 87.A O no hydrogen 3.055 N/A TYR 67.A OH SER 79.A O no hydrogen 2.607 N/A ALA 71.A N GLY 68.A O no hydrogen 3.000 N/A LEU 72.A N LYS 69.A O no hydrogen 3.058 N/A TRP 75.A NE1 TYR 99.A O no hydrogen 3.142 N/A SER 76.A OG VAL 73.A O no hydrogen 2.624 N/A ILE 78.A N ASP 101.A OD2 no hydrogen 2.845 N/A SER 79.A N ASP 101.A OD2 no hydrogen 2.894 N/A SER 79.A OG SER 76.A O no hydrogen 3.555 N/A SER 79.A OG ASP 101.A OD1 no hydrogen 2.818 N/A SER 79.A OG ASP 101.A OD2 no hydrogen 3.289 N/A GLU 80.A N SER 76.A O no hydrogen 3.026 N/A LYS 81.A N PRO 77.A O no hydrogen 3.130 N/A TYR 82.A N ILE 78.A O no hydrogen 2.904 N/A LEU 83.A N GLU 80.A O no hydrogen 3.462 N/A GLY 86.A N TYR 82.A O no hydrogen 2.866 N/A THR 88.A N GLU 91.A OE1 no hydrogen 2.983 N/A THR 88.A OG1 LEU 61.A O no hydrogen 3.359 N/A VAL 89.A N THR 63.A O no hydrogen 3.025 N/A ALA 90.A N LEU 61.A O no hydrogen 2.880 N/A GLU 91.A N THR 88.A OG1 no hydrogen 3.311 N/A LEU 92.A N THR 88.A O no hydrogen 2.931 N/A SER 93.A N VAL 89.A O no hydrogen 2.928 N/A SER 93.A OG VAL 89.A O no hydrogen 2.910 N/A ALA 94.A N ALA 90.A O no hydrogen 3.001 N/A ALA 95.A N GLU 91.A O no hydrogen 3.009 N/A ALA 96.A N LEU 92.A O no hydrogen 2.881 N/A VAL 97.A N SER 93.A O no hydrogen 3.000 N/A GLN 98.A N ALA 94.A O no hydrogen 2.833 N/A GLN 98.A NE2 TRP 180.A O no hydrogen 3.011 N/A TYR 99.A N ALA 95.A O no hydrogen 3.064 N/A ASP 101.A N ALA 95.A O no hydrogen 3.243 N/A ASN 102.A N TRP 75.A O no hydrogen 2.932 N/A ASN 102.A ND2 PRO 74.A O no hydrogen 2.820 N/A ALA 103.A N SER 76.A OG no hydrogen 2.901 N/A ALA 104.A N ASP 101.A OD1 no hydrogen 2.838 N/A ALA 105.A N ASP 101.A O no hydrogen 3.195 N/A ASN 106.A N ASN 102.A O no hydrogen 2.970 N/A ASN 106.A ND2 GLU 136.A O no hydrogen 2.980 N/A LEU 107.A N ALA 103.A O no hydrogen 2.811 N/A LEU 108.A N ALA 104.A O no hydrogen 2.976 N/A LEU 109.A N ALA 105.A O no hydrogen 2.837 N/A LYS 110.A N ASN 106.A O no hydrogen 2.993 N/A GLU 111.A N LEU 107.A O no hydrogen 3.228 N/A LEU 112.A N LEU 108.A O no hydrogen 3.097 N/A LEU 112.A N LEU 109.A O no hydrogen 3.078 N/A GLY 113.A N LYS 110.A O no hydrogen 3.347 N/A GLY 114.A N LEU 109.A O no hydrogen 2.612 N/A LEU 118.A N GLY 114.A O no hydrogen 3.103 N/A THR 119.A N PRO 115.A O no hydrogen 2.943 N/A THR 119.A OG1 PRO 115.A O no hydrogen 2.973 N/A THR 119.A OG1 LEU 132.A O no hydrogen 3.128 N/A ALA 120.A N ALA 116.A O no hydrogen 2.926 N/A PHE 121.A N GLY 117.A O no hydrogen 3.133 N/A MET 122.A N LEU 118.A O no hydrogen 3.103 N/A ARG 123.A N THR 119.A O no hydrogen 2.954 N/A ARG 123.A NH1 ASP 127.A O no hydrogen 2.785 N/A ARG 123.A NH1 PHE 130.A O no hydrogen 2.784 N/A ARG 123.A NH2 PHE 130.A O no hydrogen 2.912 N/A SER 124.A N ALA 120.A O no hydrogen 3.002 N/A SER 124.A OG PHE 121.A O no hydrogen 2.590 N/A ILE 125.A N MET 122.A O no hydrogen 3.197 N/A GLY 126.A N ARG 123.A O no hydrogen 2.883 N/A ASP 127.A N MET 122.A O no hydrogen 2.949 N/A THR 129.A N ASP 127.A OD1 no hydrogen 2.847 N/A PHE 130.A N ASP 127.A OD1 no hydrogen 2.838 N/A ARG 131.A N THR 150.A O no hydrogen 3.085 N/A ARG 131.A NE ASP 133.A OD1 no hydrogen 2.901 N/A ARG 131.A NH2 ASP 133.A OD1 no hydrogen 3.508 N/A ARG 131.A NH2 ASP 133.A OD2 no hydrogen 2.859 N/A LEU 132.A N THR 119.A OG1 no hydrogen 2.960 N/A ASP 133.A N ASP 149.A OD1 no hydrogen 2.649 N/A ARG 134.A N ASP 149.A OD1 no hydrogen 2.941 N/A ARG 134.A NE ASP 149.A OD2 no hydrogen 2.725 N/A ARG 134.A NH1 SER 141.A OG no hydrogen 3.024 N/A ARG 134.A NH2 SER 141.A OG no hydrogen 2.994 N/A ARG 134.A NH2 ASP 149.A OD2 no hydrogen 2.800 N/A GLU 136.A N ASN 106.A OD1 no hydrogen 2.994 N/A LEU 139.A N TRP 135.A O no hydrogen 2.986 N/A ASN 140.A N LEU 137.A O no hydrogen 3.134 N/A ASN 140.A ND2 GLU 136.A OE1 no hydrogen 2.808 N/A ASN 140.A ND2 LEU 137.A O no hydrogen 3.167 N/A SER 141.A N GLU 138.A O no hydrogen 3.317 N/A ASP 146.A N ILE 143.A O no hydrogen 2.962 N/A ARG 148.A N ASP 146.A OD1 no hydrogen 3.065 N/A ARG 148.A NE ASP 146.A OD1 no hydrogen 3.278 N/A ARG 148.A NE ASP 146.A OD2 no hydrogen 3.022 N/A ARG 148.A NH2 ASP 146.A OD2 no hydrogen 2.906 N/A ASP 149.A N ASP 133.A OD1 no hydrogen 2.937 N/A THR 150.A OG1 ALA 147.A O no hydrogen 2.619 N/A SER 151.A N PHE 36.A O no hydrogen 3.112 N/A SER 152.A OG ALA 32.A O no hydrogen 3.568 N/A ARG 154.A N ALA 32.A O no hydrogen 2.928 N/A ARG 154.A NE GLU 158.A OE2 no hydrogen 3.069 N/A ALA 155.A N SER 152.A OG no hydrogen 3.097 N/A VAL 156.A N SER 152.A O no hydrogen 2.947 N/A THR 157.A N PRO 153.A O no hydrogen 2.957 N/A THR 157.A OG1 TYR 18.A O no hydrogen 3.291 N/A THR 157.A OG1 PRO 153.A O no hydrogen 2.950 N/A GLU 158.A N ARG 154.A O no hydrogen 2.878 N/A SER 159.A N ALA 155.A O no hydrogen 2.883 N/A SER 159.A OG ASP 127.A OD2 no hydrogen 2.614 N/A SER 159.A OG ALA 155.A O no hydrogen 3.257 N/A LEU 160.A N VAL 156.A O no hydrogen 2.891 N/A GLN 161.A N THR 157.A O no hydrogen 2.892 N/A LYS 162.A N GLU 158.A O no hydrogen 2.998 N/A LYS 162.A NZ ILE 125.A O no hydrogen 2.918 N/A LEU 163.A N SER 159.A O no hydrogen 3.068 N/A THR 164.A N LEU 160.A O no hydrogen 2.946 N/A THR 164.A OG1 LEU 160.A O no hydrogen 2.757 N/A LEU 165.A N GLN 161.A O no hydrogen 2.898 N/A GLY 166.A N GLN 161.A O no hydrogen 2.853 N/A ALA 168.A N LYS 162.A O no hydrogen 3.234 N/A ALA 170.A N GLN 55.A OE1 no hydrogen 2.869 N/A GLN 173.A N GLN 173.A OE1 no hydrogen 2.799 N/A ARG 174.A N ALA 170.A O no hydrogen 2.796 N/A ARG 174.A NE LEU 169.A O no hydrogen 3.435 N/A ARG 174.A NH1 LEU 169.A O no hydrogen 2.864 N/A GLN 175.A N ALA 171.A O no hydrogen 3.013 N/A GLN 175.A NE2 ASP 179.A OD1 no hydrogen 2.823 N/A GLN 176.A N PRO 172.A O no hydrogen 3.047 N/A PHE 177.A N GLN 173.A O no hydrogen 2.914 N/A VAL 178.A N ARG 174.A O no hydrogen 2.955 N/A ASP 179.A N GLN 175.A O no hydrogen 2.847 N/A TRP 180.A N GLN 176.A O no hydrogen 2.937 N/A LEU 181.A N PHE 177.A O no hydrogen 3.054 N/A LYS 182.A N VAL 178.A O no hydrogen 2.876 N/A GLY 183.A N ASP 179.A O no hydrogen 3.128 N/A GLY 183.A N TRP 180.A O no hydrogen 3.224 N/A ASN 184.A N LEU 181.A O no hydrogen 3.172 N/A ASN 184.A ND2 THR 186.A OG1 no hydrogen 3.117 N/A ASN 184.A ND2 ASP 203.A OD1 no hydrogen 3.082 N/A ASN 184.A ND2 ASP 203.A OD2 no hydrogen 3.250 N/A THR 185.A N GLN 98.A O no hydrogen 3.098 N/A THR 185.A OG1 GLN 98.A O no hydrogen 2.723 N/A THR 186.A N ASN 184.A OD1 no hydrogen 3.304 N/A THR 186.A OG1 ASN 184.A OD1 no hydrogen 3.092 N/A THR 186.A OG1 THR 205.A OG1 no hydrogen 2.566 N/A ARG 190.A N GLY 187.A O no hydrogen 3.169 N/A ARG 190.A NE GLU 245.A OE2 no hydrogen 2.814 N/A ARG 190.A NH1 GLY 206.A O no hydrogen 2.893 N/A ARG 190.A NH1 THR 207.A OG1 no hydrogen 3.311 N/A ARG 190.A NH1 ASN 215.A O no hydrogen 3.009 N/A ARG 190.A NH2 THR 207.A OG1 no hydrogen 2.833 N/A ARG 190.A NH2 GLU 245.A OE2 no hydrogen 3.524 N/A ILE 191.A N ASP 216.A OD2 no hydrogen 2.952 N/A ARG 192.A NE ASP 203.A OD1 no hydrogen 2.849 N/A ARG 192.A NH2 LYS 182.A O no hydrogen 3.182 N/A ARG 192.A NH2 ASP 203.A OD1 no hydrogen 3.068 N/A ALA 193.A N ARG 190.A O no hydrogen 2.920 N/A ALA 194.A N ILE 191.A O no hydrogen 2.933 N/A VAL 195.A N ARG 192.A O no hydrogen 3.136 N/A TRP 199.A N PRO 196.A O no hydrogen 3.052 N/A GLY 202.A N VAL 219.A O no hydrogen 2.968 N/A ASP 203.A N LEU 181.A O no hydrogen 3.134 N/A LYS 204.A N TYR 217.A O no hydrogen 3.055 N/A LYS 204.A NZ SER 100.A OG no hydrogen 2.938 N/A LYS 204.A NZ THR 205.A O no hydrogen 2.848 N/A THR 205.A OG1 THR 186.A OG1 no hydrogen 2.566 N/A GLY 206.A N ASN 215.A O no hydrogen 3.051 N/A CYS 208.A N THR 213.A O no hydrogen 3.029 N/A CYS 208.A SG ASN 140.A OD1 no hydrogen 3.896 N/A TYR 211.A N LYS 239.A O no hydrogen 2.831 N/A GLY 212.A N ASP 241.A O no hydrogen 2.889 N/A THR 213.A N VAL 210.A O no hydrogen 3.040 N/A THR 213.A OG1 VAL 210.A O no hydrogen 3.473 N/A THR 213.A OG1 TYR 211.A O no hydrogen 2.790 N/A ALA 214.A N THR 234.A O no hydrogen 3.392 N/A ALA 214.A N THR 234.A OG1 no hydrogen 3.324 N/A ASN 215.A N GLY 206.A O no hydrogen 2.878 N/A ASN 215.A ND2 LEU 38.A O no hydrogen 3.001 N/A ASP 216.A N VAL 232.A O no hydrogen 2.928 N/A TYR 217.A N LYS 204.A O no hydrogen 3.110 N/A TYR 217.A OH SER 41.A O no hydrogen 2.615 N/A ALA 218.A N LEU 230.A O no hydrogen 2.914 N/A VAL 219.A N GLY 202.A O no hydrogen 2.879 N/A VAL 220.A N ILE 228.A O no hydrogen 2.749 N/A TRP 221.A N ALA 200.A O no hydrogen 2.853 N/A ARG 225.A N PRO 222.A O no hydrogen 2.989 N/A ILE 228.A N VAL 220.A O no hydrogen 2.693 N/A VAL 229.A N MET 20.A O no hydrogen 2.920 N/A LEU 230.A N ALA 218.A O no hydrogen 3.028 N/A ALA 231.A N TYR 18.A O no hydrogen 2.859 N/A VAL 232.A N ASP 216.A O no hydrogen 2.829 N/A TYR 233.A N GLY 16.A O no hydrogen 2.797 N/A TYR 233.A OH SER 41.A OG no hydrogen 2.892 N/A THR 234.A N ALA 214.A O no hydrogen 2.869 N/A THR 234.A OG1 GLY 212.A O no hydrogen 3.081 N/A THR 234.A OG1 ALA 214.A O no hydrogen 3.055 N/A ARG 235.A N SER 14.A O no hydrogen 3.008 N/A ALA 236.A N TYR 211.A O no hydrogen 2.790 N/A ASN 238.A N ASP 241.A OD2 no hydrogen 2.912 N/A ASP 241.A N ASN 238.A O no hydrogen 3.048 N/A VAL 247.A N SER 244.A OG no hydrogen 3.082 N/A ALA 249.A N GLU 245.A O no hydrogen 2.953 N/A ALA 250.A N ALA 246.A O no hydrogen 2.830 N/A ALA 251.A N VAL 247.A O no hydrogen 2.874 N/A ALA 252.A N ILE 248.A O no hydrogen 2.936 N/A ARG 253.A N ALA 249.A O no hydrogen 2.973 N/A ARG 253.A NH1.A ALA 193.A O no hydrogen 3.351 N/A LEU 254.A N ALA 250.A O no hydrogen 2.978 N/A ALA 255.A N ALA 251.A O no hydrogen 2.951 N/A LEU 256.A N ALA 252.A O no hydrogen 2.941 N/A GLU 257.A N ARG 253.A O no hydrogen 2.850 N/A GLY 258.A N LEU 254.A O no hydrogen 2.891 N/A LEU 259.A N ALA 255.A O no hydrogen 3.063 N/A LEU 259.A N LEU 256.A O no hydrogen 3.191 N/A GLY 260.A N GLU 257.A O no hydrogen 2.967 N/A VAL 261.A N LEU 256.A O no hydrogen 3.001 N/A