Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7tk9_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 6.A N VAL 71.A O no hydrogen 3.164 N/A LYS 7.A N HIS 19.A O no hydrogen 3.430 N/A VAL 8.A N GLU 69.A O no hydrogen 3.330 N/A THR 9.A N ASP 17.A O no hydrogen 2.877 N/A ILE 12.A N ILE 15.A O no hydrogen 3.191 N/A VAL 16.A N THR 56.A O no hydrogen 3.091 N/A ASP 17.A N ALA 10.A O no hydrogen 3.169 N/A VAL 18.A N VAL 54.A O no hydrogen 3.134 N/A GLU 24.A N GLU 21.A O no hydrogen 3.222 N/A LEU 29.A N VAL 45.A O no hydrogen 2.797 N/A ASN 30.A N ALA 27.A O no hydrogen 3.091 N/A LEU 32.A N LEU 43.A O no hydrogen 2.825 N/A GLU 33.A N LEU 72.A O no hydrogen 3.002 N/A ILE 34.A N LEU 41.A O no hydrogen 2.912 N/A THR 36.A N GLY 39.A O no hydrogen 2.854 N/A LEU 41.A N ILE 34.A O no hydrogen 2.925 N/A LEU 43.A N LEU 32.A O no hydrogen 2.887 N/A GLU 44.A N ILE 57.A O no hydrogen 2.995 N/A VAL 45.A N ASN 30.A O no hydrogen 3.058 N/A ALA 46.A N ARG 55.A O no hydrogen 3.316 N/A GLN 47.A N ARG 55.A O no hydrogen 2.969 N/A LEU 49.A N THR 53.A O no hydrogen 3.037 N/A THR 53.A N GLY 50.A O no hydrogen 3.170 N/A VAL 54.A N VAL 18.A O no hydrogen 3.112 N/A ARG 55.A N GLN 47.A O no hydrogen 3.148 N/A THR 56.A N VAL 16.A O no hydrogen 3.142 N/A ILE 57.A N GLU 44.A O no hydrogen 3.169 N/A ALA 58.A N ALA 14.A O no hydrogen 2.984 N/A LEU 65.A N THR 62.A O no hydrogen 3.386 N/A LEU 72.A N GLU 33.A O no hydrogen 2.939 N/A THR 74.A N ALA 31.A O no hydrogen 2.917 N/A GLY 75.A N ALA 31.A O no hydrogen 3.319 N/A VAL 80.A N LYS 110.A O no hydrogen 3.006 N/A VAL 82.A N LEU 108.A O no hydrogen 2.976 N/A GLY 88.A N VAL 210.A O no hydrogen 3.006 N/A ILE 91.A N LEU 212.A O no hydrogen 3.279 N/A ASN 92.A N GLU 96.A O no hydrogen 2.941 N/A GLY 95.A N ASN 92.A O no hydrogen 2.897 N/A ILE 98.A N ILE 90.A O no hydrogen 3.235 N/A LYS 107.A N VAL 82.A O no hydrogen 3.291 N/A LEU 108.A N VAL 82.A O no hydrogen 3.435 N/A LYS 110.A N VAL 80.A O no hydrogen 3.396 N/A ILE 112.A N ILE 78.A O no hydrogen 2.907 N/A GLU 121.A N SER 118.A O no hydrogen 3.071 N/A GLN 122.A N PHE 119.A O no hydrogen 3.301 N/A SER 123.A N THR 293.A O no hydrogen 3.106 N/A ASP 137.A N ILE 133.A O no hydrogen 2.818 N/A LEU 138.A N LYS 134.A O no hydrogen 2.944 N/A LEU 139.A N VAL 135.A O no hydrogen 2.898 N/A ALA 140.A N VAL 136.A O no hydrogen 3.046 N/A ARG 144.A N GLU 127.A O no hydrogen 3.248 N/A GLY 146.A N ALA 143.A O no hydrogen 3.063 N/A ILE 148.A N SER 301.A O no hydrogen 2.884 N/A GLY 149.A N ALA 326.A O no hydrogen 2.975 N/A LEU 150.A N GLN 303.A O no hydrogen 3.020 N/A GLY 157.A N GLY 155.A O no hydrogen 2.677 N/A PHE 161.A N GLY 157.A O no hydrogen 2.734 N/A ILE 162.A N LYS 158.A O no hydrogen 3.097 N/A GLN 163.A N THR 159.A O no hydrogen 2.869 N/A GLU 164.A N VAL 160.A O no hydrogen 2.976 N/A LEU 165.A N PHE 161.A O no hydrogen 3.028 N/A ILE 166.A N ILE 162.A O no hydrogen 2.906 N/A ASN 167.A N GLN 163.A O no hydrogen 2.888 N/A ASN 168.A N GLU 164.A O no hydrogen 2.889 N/A ILE 169.A N LEU 165.A O no hydrogen 2.835 N/A ALA 170.A N ILE 166.A O no hydrogen 3.282 N/A ALA 172.A N ASN 168.A O no hydrogen 3.071 N/A HIS 173.A N ILE 169.A O no hydrogen 2.849 N/A VAL 178.A N LEU 247.A O no hydrogen 3.281 N/A PHE 179.A N ALA 211.A O no hydrogen 3.201 N/A THR 180.A N PHE 249.A O no hydrogen 2.996 N/A GLY 181.A N VAL 213.A O no hydrogen 3.070 N/A VAL 182.A N ASP 251.A O no hydrogen 2.845 N/A GLY 183.A N GLY 215.A O no hydrogen 2.867 N/A GLY 189.A N ARG 185.A O no hydrogen 2.829 N/A ASN 190.A N THR 186.A O no hydrogen 3.196 N/A ASP 191.A N ARG 187.A O no hydrogen 3.189 N/A LEU 192.A N GLU 188.A O no hydrogen 2.896 N/A TYR 193.A N GLY 189.A O no hydrogen 2.845 N/A ARG 194.A N ASN 190.A O no hydrogen 3.008 N/A GLU 195.A N ASP 191.A O no hydrogen 2.775 N/A MET 196.A N LEU 192.A O no hydrogen 2.875 N/A LYS 197.A N TYR 193.A O no hydrogen 3.042 N/A GLU 198.A N ARG 194.A O no hydrogen 2.868 N/A THR 199.A N GLU 195.A O no hydrogen 2.847 N/A GLY 200.A N MET 196.A O no hydrogen 3.134 N/A ILE 202.A N MET 196.A O no hydrogen 3.125 N/A GLY 206.A N ASN 203.A O no hydrogen 3.339 N/A LYS 209.A N VAL 201.A O no hydrogen 3.379 N/A ALA 211.A N SER 177.A O no hydrogen 3.351 N/A LEU 212.A N ARG 89.A O no hydrogen 3.385 N/A VAL 213.A N PHE 179.A O no hydrogen 3.107 N/A GLY 215.A N GLY 181.A O no hydrogen 2.950 N/A ALA 223.A N PRO 220.A O no hydrogen 3.015 N/A ARG 224.A N PRO 220.A O no hydrogen 3.243 N/A ALA 225.A N PRO 221.A O no hydrogen 3.174 N/A ARG 226.A N ALA 223.A O no hydrogen 3.075 N/A THR 230.A N ARG 226.A O no hydrogen 3.371 N/A GLY 231.A N VAL 227.A O no hydrogen 3.143 N/A LEU 232.A N ALA 228.A O no hydrogen 2.978 N/A THR 233.A N LEU 229.A O no hydrogen 3.228 N/A THR 233.A N THR 230.A O no hydrogen 3.335 N/A ILE 234.A N GLY 231.A O no hydrogen 3.110 N/A ALA 235.A N GLY 231.A O no hydrogen 3.308 N/A GLU 236.A N LEU 232.A O no hydrogen 2.986 N/A TYR 237.A N THR 233.A O no hydrogen 3.077 N/A PHE 238.A N ILE 234.A O no hydrogen 3.039 N/A ARG 239.A N ALA 235.A O no hydrogen 2.840 N/A ASP 240.A N GLU 236.A O no hydrogen 2.786 N/A GLU 242.A N TYR 237.A O no hydrogen 2.910 N/A VAL 246.A N SER 298.A O no hydrogen 3.012 N/A PHE 249.A N VAL 178.A O no hydrogen 2.759 N/A ILE 250.A N VAL 302.A O no hydrogen 2.970 N/A ASN 252.A N VAL 182.A O no hydrogen 3.243 N/A ILE 253.A N ALA 304.A O no hydrogen 2.817 N/A ARG 255.A N ASN 252.A O no hydrogen 3.111 N/A THR 257.A N ILE 253.A O no hydrogen 3.043 N/A GLN 258.A N PHE 254.A O no hydrogen 2.733 N/A ALA 259.A N ARG 255.A O no hydrogen 3.025 N/A GLY 260.A N PHE 256.A O no hydrogen 3.249 N/A SER 261.A N THR 257.A O no hydrogen 2.943 N/A GLU 262.A N GLN 258.A O no hydrogen 3.100 N/A VAL 263.A N ALA 259.A O no hydrogen 3.216 N/A SER 264.A N GLY 260.A O no hydrogen 3.068 N/A ALA 265.A N SER 261.A O no hydrogen 3.353 N/A LEU 266.A N GLU 262.A O no hydrogen 3.286 N/A LEU 267.A N VAL 263.A O no hydrogen 2.835 N/A GLY 268.A N ALA 265.A O no hydrogen 2.940 N/A ARG 269.A N SER 264.A O no hydrogen 3.020 N/A SER 272.A N TYR 276.A O no hydrogen 2.795 N/A GLY 275.A N SER 272.A O no hydrogen 2.990 N/A TYR 276.A N ALA 273.A O no hydrogen 2.986 N/A LEU 280.A N GLN 277.A O no hydrogen 3.131 N/A ASP 283.A N THR 279.A O no hydrogen 2.971 N/A MET 284.A N LEU 280.A O no hydrogen 2.960 N/A GLY 285.A N ALA 281.A O no hydrogen 2.847 N/A LEU 286.A N THR 282.A O no hydrogen 2.868 N/A LEU 287.A N ASP 283.A O no hydrogen 3.257 N/A GLN 288.A N MET 284.A O no hydrogen 2.845 N/A GLU 289.A N GLY 285.A O no hydrogen 2.837 N/A ARG 290.A N LEU 286.A O no hydrogen 3.150 N/A ILE 291.A N GLN 288.A O no hydrogen 3.013 N/A THR 294.A N GLY 297.A O no hydrogen 2.949 N/A SER 301.A N GLY 146.A O no hydrogen 3.040 N/A VAL 302.A N LEU 248.A O no hydrogen 3.013 N/A GLN 303.A N ILE 148.A O no hydrogen 3.077 N/A ALA 304.A N ILE 250.A O no hydrogen 3.170 N/A VAL 307.A N GLY 152.A O no hydrogen 3.055 N/A ASP 310.A N VAL 307.A O no hydrogen 3.151 N/A ASP 311.A N PRO 308.A O no hydrogen 3.137 N/A ASP 314.A N ASP 311.A O no hydrogen 3.297 N/A ALA 318.A N ASP 314.A O no hydrogen 3.070 N/A THR 319.A N PRO 315.A O no hydrogen 2.876 N/A THR 320.A N ALA 316.A O no hydrogen 3.292 N/A PHE 321.A N PRO 317.A O no hydrogen 2.860 N/A HIS 323.A N THR 319.A O no hydrogen 3.357 N/A ASP 325.A N LYS 147.A O no hydrogen 3.338 N/A ALA 326.A N LYS 147.A O no hydrogen 3.142 N/A LEU 330.A N PHE 151.A O no hydrogen 2.994 N/A SER 331.A N ALA 342.A O no hydrogen 2.843 N/A SER 335.A N SER 331.A O no hydrogen 3.402 N/A GLU 336.A N ARG 332.A O no hydrogen 2.985 N/A LEU 337.A N GLY 333.A O no hydrogen 2.904 N/A GLY 338.A N SER 335.A O no hydrogen 2.885 N/A ILE 339.A N ILE 334.A O no hydrogen 3.186 N/A ASP 344.A N VAL 329.A O no hydrogen 2.930 N/A ASP 347.A N ASP 344.A O no hydrogen 3.219 N/A SER 348.A N PRO 345.A O no hydrogen 3.495 N/A GLY 359.A N ALA 356.A O no hydrogen 3.036 N/A TYR 363.A N GLY 359.A O no hydrogen 2.845 N/A ASP 364.A N GLN 360.A O no hydrogen 2.943 N/A VAL 365.A N GLU 361.A O no hydrogen 2.869 N/A ALA 366.A N HIS 362.A O no hydrogen 2.889 N/A SER 367.A N TYR 363.A O no hydrogen 2.796 N/A LYS 368.A N ASP 364.A O no hydrogen 2.913 N/A VAL 369.A N VAL 365.A O no hydrogen 2.901 N/A GLN 370.A N ALA 366.A O no hydrogen 3.075 N/A GLU 371.A N SER 367.A O no hydrogen 3.055 N/A THR 372.A N LYS 368.A O no hydrogen 3.000 N/A LEU 373.A N VAL 369.A O no hydrogen 3.000 N/A GLN 374.A N GLN 370.A O no hydrogen 2.863 N/A THR 375.A N GLU 371.A O no hydrogen 2.830 N/A TYR 376.A N THR 372.A O no hydrogen 2.945 N/A LYS 377.A N LEU 373.A O no hydrogen 2.984 N/A SER 378.A N GLN 374.A O no hydrogen 2.983 N/A LEU 379.A N THR 375.A O no hydrogen 2.803 N/A GLN 380.A N LYS 377.A O no hydrogen 3.221 N/A ILE 383.A N LEU 379.A O no hydrogen 2.895 N/A ALA 384.A N GLN 380.A O no hydrogen 2.938 N/A ILE 385.A N ASP 381.A O no hydrogen 3.395 N/A LEU 386.A N ILE 382.A O no hydrogen 2.956 N/A GLY 387.A N ILE 382.A O no hydrogen 3.328 N/A LEU 391.A N MET 388.A O no hydrogen 3.367 N/A LYS 396.A N SER 392.A O no hydrogen 2.910 N/A LEU 397.A N GLU 393.A O no hydrogen 3.014 N/A THR 398.A N GLN 394.A O no hydrogen 2.998 N/A VAL 399.A N ASP 395.A O no hydrogen 2.775 N/A GLU 400.A N LYS 396.A O no hydrogen 2.975 N/A ARG 401.A N LEU 397.A O no hydrogen 2.969 N/A ALA 402.A N THR 398.A O no hydrogen 2.893 N/A ARG 403.A N VAL 399.A O no hydrogen 3.000 N/A LYS 404.A N GLU 400.A O no hydrogen 3.195 N/A ILE 405.A N ARG 401.A O no hydrogen 2.795 N/A GLN 406.A N ALA 402.A O no hydrogen 2.805 N/A ARG 407.A N ARG 403.A O no hydrogen 3.291 N/A PHE 408.A N ILE 405.A O no hydrogen 2.906 N/A LEU 409.A N ILE 405.A O no hydrogen 2.952 N/A ALA 416.A N PHE 413.A O no hydrogen 2.979 N/A GLU 417.A N ALA 414.A O no hydrogen 3.085 N/A GLY 421.A N ALA 416.A O no hydrogen 2.981 N/A LYS 425.A N PRO 412.A O no hydrogen 2.976 N/A VAL 427.A N GLY 132.A O no hydrogen 2.940 N/A THR 432.A N ARG 428.A O no hydrogen 3.103 N/A VAL 433.A N LEU 429.A O no hydrogen 3.144 N/A ALA 434.A N LYS 430.A O no hydrogen 3.195 N/A SER 435.A N ASP 431.A O no hydrogen 3.062 N/A PHE 436.A N THR 432.A O no hydrogen 2.946 N/A LYS 437.A N VAL 433.A O no hydrogen 3.222 N/A ALA 438.A N ALA 434.A O no hydrogen 3.367 N/A VAL 439.A N SER 435.A O no hydrogen 3.373 N/A LEU 440.A N PHE 436.A O no hydrogen 3.234 N/A GLU 441.A N LYS 437.A O no hydrogen 3.112 N/A GLY 442.A N ALA 438.A O no hydrogen 3.057 N/A GLY 442.A N VAL 439.A O no hydrogen 2.896 N/A LYS 443.A N ALA 438.A O no hydrogen 3.064 N/A ASP 445.A N GLY 442.A O no hydrogen 3.345 N/A ILE 447.A N TYR 444.A O no hydrogen 3.336 N/A ALA 451.A N PRO 448.A O no hydrogen 3.093 N/A PHE 452.A N GLU 449.A O no hydrogen 3.121 N/A TYR 453.A N GLU 449.A O no hydrogen 3.310 N/A VAL 455.A N PHE 452.A O no hydrogen 3.271 N/A VAL 461.A N GLY 457.A O no hydrogen 2.894 N/A VAL 462.A N ILE 458.A O no hydrogen 2.890 N/A ALA 463.A N GLU 459.A O no hydrogen 2.919 N/A LYS 464.A N ASP 460.A O no hydrogen 2.785 N/A ALA 465.A N VAL 461.A O no hydrogen 2.989 N/A GLU 466.A N VAL 462.A O no hydrogen 3.031 N/A LYS 467.A N ALA 463.A O no hydrogen 2.894 N/A LEU 468.A N LYS 464.A O no hydrogen 3.046 N/A ALA 469.A N ALA 465.A O no hydrogen 2.986 N/A ALA 470.A N GLU 466.A O no hydrogen 2.974 N/A