Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7tko_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 5.A N HIS 17.A O no hydrogen 2.828 N/A VAL 6.A N GLU 67.A O no hydrogen 3.198 N/A THR 7.A N ASP 15.A O no hydrogen 2.802 N/A ALA 8.A N ASP 15.A O no hydrogen 3.067 N/A ILE 10.A N ILE 13.A O no hydrogen 3.143 N/A ILE 13.A N ILE 10.A O no hydrogen 3.044 N/A ASP 15.A N ALA 8.A O no hydrogen 3.084 N/A HIS 17.A N LYS 5.A O no hydrogen 2.916 N/A PHE 18.A N ASN 50.A O no hydrogen 2.763 N/A GLU 19.A N THR 3.A O no hydrogen 3.394 N/A GLU 22.A N GLU 19.A O no hydrogen 3.291 N/A LEU 27.A N VAL 43.A O no hydrogen 2.869 N/A ASN 28.A N ALA 25.A O no hydrogen 3.072 N/A LEU 30.A N LEU 41.A O no hydrogen 2.811 N/A GLU 31.A N LEU 70.A O no hydrogen 2.865 N/A ILE 32.A N LEU 39.A O no hydrogen 2.841 N/A THR 34.A N GLY 37.A O no hydrogen 2.975 N/A LEU 39.A N ILE 32.A O no hydrogen 2.817 N/A LEU 41.A N LEU 30.A O no hydrogen 2.888 N/A GLU 42.A N ILE 55.A O no hydrogen 2.800 N/A VAL 43.A N ASN 28.A O no hydrogen 2.985 N/A ALA 44.A N ARG 53.A O no hydrogen 3.026 N/A THR 51.A N GLY 48.A O no hydrogen 3.041 N/A VAL 52.A N VAL 16.A O no hydrogen 3.005 N/A ARG 53.A N GLN 45.A O no hydrogen 3.154 N/A THR 54.A N VAL 14.A O no hydrogen 3.325 N/A ILE 55.A N GLU 42.A O no hydrogen 2.920 N/A MET 57.A N VAL 40.A O no hydrogen 2.962 N/A LEU 63.A N THR 60.A O no hydrogen 3.434 N/A GLU 67.A N VAL 64.A O no hydrogen 3.326 N/A LEU 70.A N GLU 31.A O no hydrogen 3.114 N/A THR 72.A N ALA 29.A O no hydrogen 2.816 N/A GLY 73.A N ALA 29.A O no hydrogen 3.422 N/A VAL 78.A N LYS 108.A O no hydrogen 3.313 N/A VAL 80.A N LEU 106.A O no hydrogen 2.882 N/A THR 84.A N GLY 81.A O no hydrogen 3.223 N/A LEU 85.A N ARG 82.A O no hydrogen 3.164 N/A ASN 90.A N GLU 94.A O no hydrogen 3.017 N/A GLY 93.A N ASN 90.A O no hydrogen 2.938 N/A ILE 96.A N ILE 88.A O no hydrogen 2.898 N/A LYS 108.A N VAL 78.A O no hydrogen 3.089 N/A GLN 120.A N SER 116.A O no hydrogen 3.107 N/A GLN 120.A N PHE 117.A O no hydrogen 3.252 N/A LEU 127.A N TYR 140.A O no hydrogen 2.837 N/A ASP 135.A N ILE 131.A O no hydrogen 3.031 N/A LEU 136.A N LYS 132.A O no hydrogen 2.894 N/A LEU 137.A N VAL 133.A O no hydrogen 3.045 N/A ALA 138.A N VAL 134.A O no hydrogen 2.972 N/A ARG 142.A N GLU 125.A O no hydrogen 3.022 N/A GLY 144.A N ALA 141.A O no hydrogen 3.108 N/A ILE 146.A N SER 299.A O no hydrogen 2.952 N/A GLY 147.A N ALA 324.A O no hydrogen 3.094 N/A LEU 148.A N GLN 301.A O no hydrogen 2.854 N/A GLY 155.A N ALA 152.A O no hydrogen 3.020 N/A LYS 156.A N GLY 151.A O no hydrogen 2.902 N/A VAL 158.A N GLY 153.A O no hydrogen 3.352 N/A PHE 159.A N GLY 155.A O no hydrogen 3.045 N/A ILE 160.A N LYS 156.A O no hydrogen 2.846 N/A GLN 161.A N THR 157.A O no hydrogen 2.965 N/A GLU 162.A N VAL 158.A O no hydrogen 3.003 N/A LEU 163.A N PHE 159.A O no hydrogen 3.240 N/A ILE 164.A N ILE 160.A O no hydrogen 3.340 N/A ASN 165.A N GLN 161.A O no hydrogen 3.219 N/A ASN 166.A N GLU 162.A O no hydrogen 2.928 N/A ILE 167.A N LEU 163.A O no hydrogen 2.882 N/A ALA 168.A N ILE 164.A O no hydrogen 3.031 N/A LYS 169.A N ASN 165.A O no hydrogen 3.134 N/A ALA 170.A N ASN 166.A O no hydrogen 2.734 N/A HIS 171.A N ILE 167.A O no hydrogen 2.833 N/A GLY 172.A N ILE 167.A O no hydrogen 2.920 N/A PHE 174.A N ASP 243.A O no hydrogen 3.418 N/A VAL 176.A N LEU 245.A O no hydrogen 3.123 N/A PHE 177.A N ALA 209.A O no hydrogen 3.168 N/A THR 178.A N PHE 247.A O no hydrogen 3.120 N/A GLY 179.A N VAL 211.A O no hydrogen 3.116 N/A GLU 182.A N GLY 213.A O no hydrogen 3.043 N/A GLY 187.A N ARG 183.A O no hydrogen 2.808 N/A ASN 188.A N THR 184.A O no hydrogen 2.992 N/A ASP 189.A N ARG 185.A O no hydrogen 3.112 N/A LEU 190.A N GLU 186.A O no hydrogen 2.900 N/A TYR 191.A N GLY 187.A O no hydrogen 2.935 N/A ARG 192.A N ASN 188.A O no hydrogen 2.897 N/A GLU 193.A N ASP 189.A O no hydrogen 2.744 N/A MET 194.A N LEU 190.A O no hydrogen 2.848 N/A LYS 195.A N TYR 191.A O no hydrogen 2.980 N/A GLU 196.A N ARG 192.A O no hydrogen 2.943 N/A THR 197.A N GLU 193.A O no hydrogen 2.813 N/A GLY 198.A N LYS 195.A O no hydrogen 3.040 N/A VAL 199.A N MET 194.A O no hydrogen 3.044 N/A ILE 200.A N MET 194.A O no hydrogen 3.215 N/A LYS 207.A N VAL 199.A O no hydrogen 3.114 N/A ALA 209.A N SER 175.A O no hydrogen 3.230 N/A LEU 210.A N ARG 87.A O no hydrogen 3.387 N/A VAL 211.A N PHE 177.A O no hydrogen 3.088 N/A GLY 213.A N GLY 179.A O no hydrogen 3.069 N/A GLU 217.A N GLN 214.A O no hydrogen 3.262 N/A ARG 222.A N PRO 218.A O no hydrogen 3.034 N/A ALA 223.A N PRO 219.A O no hydrogen 2.905 N/A ARG 224.A N GLY 220.A O no hydrogen 2.970 N/A THR 228.A N ARG 224.A O no hydrogen 3.085 N/A GLY 229.A N VAL 225.A O no hydrogen 3.075 N/A LEU 230.A N ALA 226.A O no hydrogen 3.043 N/A THR 231.A N LEU 227.A O no hydrogen 3.203 N/A ILE 232.A N THR 228.A O no hydrogen 3.380 N/A ALA 233.A N GLY 229.A O no hydrogen 3.192 N/A GLU 234.A N LEU 230.A O no hydrogen 2.921 N/A TYR 235.A N THR 231.A O no hydrogen 3.069 N/A PHE 236.A N ILE 232.A O no hydrogen 3.172 N/A ARG 237.A N ALA 233.A O no hydrogen 2.860 N/A ASP 238.A N GLU 234.A O no hydrogen 2.871 N/A GLU 239.A N TYR 235.A O no hydrogen 2.902 N/A GLU 240.A N PHE 236.A O no hydrogen 3.008 N/A VAL 244.A N SER 296.A O no hydrogen 3.107 N/A LEU 246.A N THR 298.A O no hydrogen 2.805 N/A PHE 247.A N VAL 176.A O no hydrogen 2.923 N/A ILE 248.A N VAL 300.A O no hydrogen 3.059 N/A ILE 251.A N ALA 302.A O no hydrogen 3.012 N/A PHE 254.A N ASN 250.A O no hydrogen 3.276 N/A THR 255.A N ILE 251.A O no hydrogen 2.904 N/A GLN 256.A N PHE 252.A O no hydrogen 2.753 N/A ALA 257.A N ARG 253.A O no hydrogen 3.026 N/A GLY 258.A N PHE 254.A O no hydrogen 3.045 N/A SER 259.A N THR 255.A O no hydrogen 2.844 N/A GLU 260.A N GLN 256.A O no hydrogen 3.229 N/A VAL 261.A N ALA 257.A O no hydrogen 3.225 N/A SER 262.A N GLY 258.A O no hydrogen 3.043 N/A ALA 263.A N SER 259.A O no hydrogen 3.188 N/A LEU 264.A N GLU 260.A O no hydrogen 2.828 N/A LEU 265.A N VAL 261.A O no hydrogen 3.020 N/A GLY 266.A N ALA 263.A O no hydrogen 2.973 N/A ARG 267.A N SER 262.A O no hydrogen 3.011 N/A SER 270.A N TYR 274.A O no hydrogen 2.710 N/A TYR 274.A N SER 270.A O no hydrogen 3.079 N/A ASP 281.A N THR 277.A O no hydrogen 3.331 N/A MET 282.A N LEU 278.A O no hydrogen 3.377 N/A GLY 283.A N ALA 279.A O no hydrogen 2.879 N/A LEU 284.A N THR 280.A O no hydrogen 2.959 N/A LEU 285.A N ASP 281.A O no hydrogen 3.229 N/A GLN 286.A N MET 282.A O no hydrogen 2.826 N/A ARG 288.A N LEU 284.A O no hydrogen 3.159 N/A THR 292.A N GLY 295.A O no hydrogen 2.929 N/A VAL 297.A N THR 290.A O no hydrogen 3.246 N/A SER 299.A N GLY 144.A O no hydrogen 2.947 N/A VAL 300.A N LEU 246.A O no hydrogen 2.900 N/A GLN 301.A N ILE 146.A O no hydrogen 3.041 N/A ALA 302.A N ASP 249.A O no hydrogen 3.397 N/A ASP 309.A N PRO 306.A O no hydrogen 3.175 N/A ASP 312.A N ASP 309.A O no hydrogen 3.253 N/A ALA 316.A N ASP 312.A O no hydrogen 3.204 N/A THR 317.A N PRO 313.A O no hydrogen 2.941 N/A THR 318.A N ALA 314.A O no hydrogen 3.304 N/A PHE 319.A N PRO 315.A O no hydrogen 2.883 N/A ALA 320.A N ALA 316.A O no hydrogen 3.146 N/A LEU 322.A N THR 318.A O no hydrogen 2.988 N/A ASP 323.A N LYS 145.A O no hydrogen 2.921 N/A ALA 324.A N LYS 145.A O no hydrogen 3.053 N/A THR 325.A N LYS 347.A O no hydrogen 2.917 N/A THR 326.A N GLY 147.A O no hydrogen 3.196 N/A LEU 328.A N PHE 149.A O no hydrogen 3.030 N/A SER 329.A N ALA 340.A O no hydrogen 3.085 N/A SER 333.A N SER 329.A O no hydrogen 3.380 N/A GLU 334.A N ARG 330.A O no hydrogen 2.844 N/A LEU 335.A N ILE 332.A O no hydrogen 3.017 N/A GLY 336.A N SER 333.A O no hydrogen 3.003 N/A ILE 337.A N ILE 332.A O no hydrogen 3.218 N/A ASP 342.A N VAL 327.A O no hydrogen 3.176 N/A SER 346.A N ASP 342.A O no hydrogen 2.849 N/A LYS 347.A N THR 325.A O no hydrogen 3.100 N/A VAL 355.A N ASP 352.A O no hydrogen 3.085 N/A VAL 356.A N ASP 352.A O no hydrogen 2.871 N/A TYR 361.A N GLY 357.A O no hydrogen 2.938 N/A ASP 362.A N GLN 358.A O no hydrogen 2.788 N/A VAL 363.A N GLU 359.A O no hydrogen 2.839 N/A ALA 364.A N HIS 360.A O no hydrogen 2.871 N/A SER 365.A N TYR 361.A O no hydrogen 2.791 N/A LYS 366.A N ASP 362.A O no hydrogen 2.990 N/A VAL 367.A N VAL 363.A O no hydrogen 2.944 N/A GLN 368.A N ALA 364.A O no hydrogen 2.817 N/A GLU 369.A N SER 365.A O no hydrogen 2.787 N/A THR 370.A N LYS 366.A O no hydrogen 2.719 N/A LEU 371.A N VAL 367.A O no hydrogen 3.025 N/A GLN 372.A N GLN 368.A O no hydrogen 2.792 N/A THR 373.A N GLU 369.A O no hydrogen 2.815 N/A TYR 374.A N THR 370.A O no hydrogen 2.849 N/A LYS 375.A N LEU 371.A O no hydrogen 2.890 N/A SER 376.A N GLN 372.A O no hydrogen 3.306 N/A LEU 377.A N THR 373.A O no hydrogen 2.774 N/A GLN 378.A N TYR 374.A O no hydrogen 2.783 N/A ASP 379.A N SER 376.A O no hydrogen 3.224 N/A ILE 380.A N LEU 377.A O no hydrogen 3.206 N/A ILE 381.A N LEU 377.A O no hydrogen 2.768 N/A ALA 382.A N GLN 378.A O no hydrogen 2.942 N/A LEU 384.A N ILE 380.A O no hydrogen 2.745 N/A GLY 385.A N ILE 381.A O no hydrogen 2.808 N/A GLU 388.A N GLY 385.A O no hydrogen 3.355 N/A LYS 394.A N SER 390.A O no hydrogen 2.823 N/A LEU 395.A N GLU 391.A O no hydrogen 3.213 N/A THR 396.A N GLN 392.A O no hydrogen 3.207 N/A VAL 397.A N ASP 393.A O no hydrogen 2.839 N/A GLU 398.A N LYS 394.A O no hydrogen 2.911 N/A ARG 399.A N LEU 395.A O no hydrogen 3.166 N/A ALA 400.A N THR 396.A O no hydrogen 2.726 N/A ARG 401.A N VAL 397.A O no hydrogen 3.001 N/A LYS 402.A N GLU 398.A O no hydrogen 3.223 N/A ILE 403.A N ARG 399.A O no hydrogen 2.749 N/A GLN 404.A N ALA 400.A O no hydrogen 2.775 N/A ARG 405.A N ARG 401.A O no hydrogen 3.179 N/A PHE 406.A N LYS 402.A O no hydrogen 2.836 N/A LEU 407.A N ILE 403.A O no hydrogen 2.918 N/A ALA 414.A N PHE 411.A O no hydrogen 3.097 N/A GLU 415.A N ALA 412.A O no hydrogen 3.030 N/A THR 418.A N ALA 414.A O no hydrogen 2.890 N/A GLY 419.A N GLU 415.A O no hydrogen 2.799 N/A VAL 425.A N GLY 130.A O no hydrogen 3.288 N/A THR 430.A N ARG 426.A O no hydrogen 2.923 N/A THR 430.A N LEU 427.A O no hydrogen 3.075 N/A VAL 431.A N LEU 427.A O no hydrogen 3.313 N/A ALA 432.A N LYS 428.A O no hydrogen 3.256 N/A SER 433.A N ASP 429.A O no hydrogen 3.319 N/A SER 433.A N THR 430.A O no hydrogen 3.243 N/A LYS 435.A N VAL 431.A O no hydrogen 3.103 N/A ALA 436.A N ALA 432.A O no hydrogen 3.157 N/A VAL 437.A N SER 433.A O no hydrogen 3.363 N/A LEU 438.A N PHE 434.A O no hydrogen 2.988 N/A GLU 439.A N LYS 435.A O no hydrogen 2.827 N/A GLY 440.A N VAL 437.A O no hydrogen 3.122 N/A LYS 441.A N ALA 436.A O no hydrogen 3.097 N/A ASP 443.A N GLY 440.A O no hydrogen 3.019 N/A ILE 445.A N TYR 442.A O no hydrogen 3.420 N/A ALA 449.A N PRO 446.A O no hydrogen 3.276 N/A PHE 450.A N GLU 447.A O no hydrogen 3.295 N/A VAL 453.A N SER 408.A O no hydrogen 3.013 N/A VAL 459.A N GLY 455.A O no hydrogen 3.351 N/A VAL 460.A N GLU 457.A O no hydrogen 3.178 N/A LYS 462.A N ASP 458.A O no hydrogen 3.006 N/A ALA 463.A N VAL 459.A O no hydrogen 3.035 N/A LYS 465.A N ALA 461.A O no hydrogen 3.069 N/A LEU 466.A N LYS 462.A O no hydrogen 2.762 N/A ALA 467.A N ALA 463.A O no hydrogen 3.330 N/A ALA 468.A N GLU 464.A O no hydrogen 2.948 N/A