Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7tza_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N HIS 2.A ND1 no hydrogen 2.990 N/A ARG 5.A N HIS 2.A O no hydrogen 2.896 N/A ARG 5.A NE GLY 222.A O no hydrogen 3.173 N/A ARG 5.A NH2 GLY 222.A O no hydrogen 2.948 N/A LEU 6.A N LEU 224.A O no hydrogen 2.807 N/A GLY 10.A N LEU 18.A O no hydrogen 2.930 N/A LEU 12.A N LEU 16.A O no hydrogen 2.771 N/A ASP 13.A N LEU 16.A O no hydrogen 3.210 N/A ASP 14.A N ASP 13.A OD1 no hydrogen 2.666 N/A LEU 16.A N ASP 13.A O no hydrogen 3.169 N/A CYS 17.A N LEU 28.A O no hydrogen 2.929 N/A LEU 18.A N GLY 10.A O no hydrogen 2.774 N/A LEU 19.A N VAL 26.A O no hydrogen 2.714 N/A GLY 20.A N ASP 53.A OD2 no hydrogen 2.637 N/A GLN 23.A N ASP 21.A OD1 no hydrogen 2.914 N/A GLN 23.A NE2 ASP 21.A OD2 no hydrogen 2.951 N/A VAL 24.A N ASP 21.A O no hydrogen 2.971 N/A VAL 26.A N LEU 19.A O no hydrogen 3.131 N/A PHE 27.A N VAL 39.A O no hydrogen 2.913 N/A LEU 28.A N CYS 17.A O no hydrogen 2.839 N/A LEU 29.A N ALA 37.A O no hydrogen 2.722 N/A ARG 30.A N ASP 15.A O no hydrogen 2.876 N/A ARG 30.A NH1 GLY 32.A O no hydrogen 3.270 N/A ARG 30.A NH1 GLU 33.A O no hydrogen 3.411 N/A LEU 31.A N SER 35.A O no hydrogen 2.721 N/A GLY 32.A N SER 35.A O no hydrogen 3.136 N/A SER 35.A OG HIS 65.A ND1 no hydrogen 2.538 N/A TRP 36.A N GLN 63.A O no hydrogen 2.992 N/A ALA 37.A N LEU 29.A O no hydrogen 2.815 N/A LEU 38.A N TYR 66.A O no hydrogen 2.977 N/A VAL 39.A N PHE 27.A O no hydrogen 2.846 N/A GLU 40.A N LEU 68.A O no hydrogen 2.907 N/A SER 44.A N ASN 115.A OD1 no hydrogen 2.768 N/A SER 44.A OG GLY 78.A O no hydrogen 2.659 N/A ARG 45.A NE ASP 46.A OD1 no hydrogen 2.867 N/A ARG 45.A NH1 LEU 118.A O no hydrogen 2.758 N/A ARG 45.A NH1 ASP 275.A O no hydrogen 3.494 N/A ARG 45.A NH2 ASP 275.A O no hydrogen 2.877 N/A ASP 46.A N ILE 43.A O no hydrogen 3.139 N/A ALA 47.A N SER 44.A O no hydrogen 2.935 N/A VAL 50.A N ASP 46.A O no hydrogen 2.822 N/A TRP 51.A N ALA 47.A O no hydrogen 2.842 N/A ALA 52.A N GLU 48.A O no hydrogen 2.812 N/A ASP 53.A N LEU 49.A O no hydrogen 2.973 N/A LEU 54.A N VAL 50.A O no hydrogen 2.740 N/A CYS 55.A N TRP 51.A O no hydrogen 2.962 N/A CYS 55.A SG TRP 51.A O no hydrogen 3.377 N/A ARG 56.A N ALA 52.A O no hydrogen 3.264 N/A ARG 56.A N ASP 53.A O no hydrogen 3.069 N/A TRP 57.A N LEU 54.A O no hydrogen 2.959 N/A VAL 58.A N LEU 54.A O no hydrogen 2.863 N/A SER 62.A N ASP 60.A OD1 no hydrogen 3.032 N/A SER 62.A OG ASP 60.A OD1 no hydrogen 2.769 N/A SER 62.A OG ASP 60.A OD2 no hydrogen 3.214 N/A GLN 63.A N ASP 60.A O no hydrogen 2.998 N/A VAL 64.A N PRO 61.A O no hydrogen 3.239 N/A HIS 65.A N TRP 36.A O no hydrogen 2.820 N/A HIS 65.A ND1 SER 35.A OG no hydrogen 2.538 N/A TRP 67.A N GLN 91.A O no hydrogen 2.927 N/A TRP 67.A NE1 GLU 40.A O no hydrogen 2.909 N/A LEU 68.A N LEU 38.A O no hydrogen 2.798 N/A ILE 69.A N LEU 93.A O no hydrogen 3.039 N/A THR 70.A OG1 GLU 40.A OE1 no hydrogen 2.973 N/A THR 70.A OG1 GLU 40.A OE2 no hydrogen 3.314 N/A THR 70.A OG1 HIS 71.A ND1 no hydrogen 2.949 N/A HIS 71.A ND1 THR 70.A OG1 no hydrogen 2.949 N/A LYS 72.A NZ ASP 161.A OD1 no hydrogen 2.893 N/A TYR 74.A OH PHE 276.A O no hydrogen 2.502 N/A ASP 75.A N ASP 75.A OD1 no hydrogen 2.586 N/A HIS 76.A N HIS 73.A O no hydrogen 2.876 N/A HIS 76.A ND1 GLU 40.A OE1 no hydrogen 2.927 N/A CYS 77.A SG LYS 72.A O no hydrogen 3.499 N/A CYS 77.A SG HIS 73.A O no hydrogen 3.478 N/A GLY 78.A N GLY 42.A O no hydrogen 2.838 N/A LEU 79.A N GLY 41.A O no hydrogen 2.868 N/A LEU 80.A N CYS 77.A O no hydrogen 3.204 N/A TYR 82.A N LEU 79.A O no hydrogen 2.972 N/A LEU 83.A N LEU 79.A O no hydrogen 3.015 N/A CYS 84.A N LEU 80.A O no hydrogen 3.111 N/A CYS 84.A SG LEU 80.A O no hydrogen 3.356 N/A ARG 86.A N LEU 83.A O no hydrogen 2.736 N/A ARG 86.A NH1 GLU 48.A OE1 no hydrogen 2.950 N/A ARG 86.A NH2 GLU 48.A OE1 no hydrogen 3.449 N/A ARG 86.A NH2 GLU 48.A OE2 no hydrogen 2.706 N/A LEU 87.A N CYS 84.A O no hydrogen 2.851 N/A ASN 89.A ND2 SER 62.A O no hydrogen 2.875 N/A VAL 90.A N LEU 87.A O no hydrogen 3.172 N/A GLN 91.A N HIS 65.A O no hydrogen 2.910 N/A VAL 92.A N PRO 133.A O no hydrogen 2.775 N/A LEU 93.A N TRP 67.A O no hydrogen 2.806 N/A SER 95.A OG THR 98.A OG1 no hydrogen 2.942 N/A SER 95.A OG ASP 162.A O no hydrogen 3.053 N/A ARG 97.A NH1.A ASP 161.A O no hydrogen 2.773 N/A THR 98.A N SER 95.A OG no hydrogen 3.299 N/A THR 98.A OG1 SER 95.A OG no hydrogen 2.942 N/A THR 98.A OG1 ASP 162.A O no hydrogen 3.519 N/A THR 98.A OG1 ASP 162.A OD2 no hydrogen 2.492 N/A CYS 99.A N SER 95.A O no hydrogen 2.990 N/A CYS 99.A SG ALA 94.A O no hydrogen 3.808 N/A CYS 99.A SG SER 95.A O no hydrogen 3.272 N/A GLN 100.A N GLU 96.A O no hydrogen 2.923 N/A GLN 100.A NE2 GLU 96.A OE1 no hydrogen 3.527 N/A ALA 101.A N ARG 97.A O no hydrogen 2.998 N/A TRP 102.A N CYS 99.A O no hydrogen 3.032 N/A LYS 103.A N CYS 99.A O no hydrogen 3.335 N/A LYS 103.A N GLN 100.A O no hydrogen 3.020 N/A LYS 103.A NZ ASP 130.A O no hydrogen 2.974 N/A SER 104.A N ALA 101.A O no hydrogen 3.210 N/A SER 106.A OG.B SER 104.A OG no hydrogen 3.084 N/A ALA 107.A N SER 104.A OG no hydrogen 3.097 N/A VAL 108.A N SER 104.A O no hydrogen 2.942 N/A ARG 109.A N GLU 105.A O no hydrogen 3.059 N/A VAL 110.A N SER 106.A O no hydrogen 3.222 N/A VAL 111.A N ALA 107.A O no hydrogen 3.094 N/A GLU 112.A N VAL 108.A O no hydrogen 2.929 N/A ARG 113.A N ARG 109.A O no hydrogen 3.032 N/A LEU 114.A N VAL 110.A O no hydrogen 2.907 N/A ASN 115.A N VAL 111.A O no hydrogen 3.113 N/A ASN 115.A ND2 TYR 74.A O no hydrogen 3.044 N/A ASN 115.A ND2 VAL 111.A O no hydrogen 2.895 N/A ARG 116.A N GLU 112.A O no hydrogen 2.890 N/A ARG 116.A NH2 GLU 112.A OE1 no hydrogen 2.739 N/A GLN 117.A N ARG 113.A O no hydrogen 3.273 N/A LEU 118.A N ASN 115.A O no hydrogen 3.028 N/A LEU 119.A N ARG 116.A O no hydrogen 3.065 N/A ARG 120.A N GLN 121.A OE1 no hydrogen 3.056 N/A GLN 121.A NE2 ARG 45.A O no hydrogen 3.591 N/A CYS 127.A N PRO 81.A O no hydrogen 3.187 N/A CYS 127.A SG PRO 81.A O no hydrogen 3.996 N/A CYS 127.A SG ALA 128.A O no hydrogen 3.618 N/A TRP 129.A NE1 GLU 112.A OE2 no hydrogen 3.096 N/A ALA 131.A N ALA 128.A O no hydrogen 3.024 N/A LEU 132.A N TRP 129.A O no hydrogen 3.196 N/A VAL 134.A N LEU 132.A O no hydrogen 2.766 N/A ARG 135.A N VAL 92.A O no hydrogen 2.761 N/A ARG 135.A NH2 GLU 141.A OE2 no hydrogen 2.576 N/A VAL 137.A N ALA 94.A O no hydrogen 2.836 N/A ALA 138.A N GLU 141.A OE1 no hydrogen 3.196 N/A GLY 140.A N VAL 153.A O no hydrogen 2.739 N/A GLU 141.A N ALA 138.A O no hydrogen 2.917 N/A LEU 143.A N LEU 151.A O no hydrogen 2.699 N/A LEU 145.A N LEU 143.A O no hydrogen 3.022 N/A LEU 145.A N HIS 149.A O no hydrogen 2.971 N/A GLY 146.A N HIS 149.A O no hydrogen 3.174 N/A HIS 149.A N GLY 146.A O no hydrogen 3.138 N/A HIS 149.A NE2 ASP 15.A OD2 no hydrogen 2.756 N/A ARG 150.A NE GLU 144.A OE1 no hydrogen 2.965 N/A ARG 150.A NE GLU 144.A OE2 no hydrogen 2.772 N/A ARG 150.A NH2 GLU 144.A OE2 no hydrogen 2.803 N/A LEU 151.A N LEU 143.A O no hydrogen 3.025 N/A GLN 152.A N TYR 167.A O no hydrogen 2.901 N/A GLN 152.A NE2 GLY 140.A O no hydrogen 3.145 N/A VAL 153.A N GLU 141.A O no hydrogen 2.814 N/A ILE 154.A N VAL 165.A O no hydrogen 2.936 N/A GLU 155.A N ASP 139.A OD1 no hydrogen 2.871 N/A ALA 156.A N HIS 163.A O no hydrogen 2.913 N/A GLY 158.A N SER 160.A O no hydrogen 3.216 N/A HIS 159.A ND1 LEU 193.A O no hydrogen 2.866 N/A SER 160.A OG ASP 162.A OD1 no hydrogen 2.729 N/A HIS 163.A N SER 160.A O no hydrogen 3.503 N/A VAL 164.A N THR 70.A O no hydrogen 2.868 N/A VAL 165.A N ILE 154.A O no hydrogen 2.883 N/A PHE 166.A N PHE 175.A O no hydrogen 3.069 N/A TYR 167.A N GLN 152.A O no hydrogen 3.041 N/A ASP 168.A N ARG 173.A O no hydrogen 2.721 N/A ARG 171.A N ASP 168.A O no hydrogen 3.250 N/A ARG 171.A N ASP 168.A OD1 no hydrogen 3.378 N/A ARG 171.A NH1 ARG 148.A O no hydrogen 2.825 N/A ARG 171.A NH1 ASP 168.A OD1 no hydrogen 3.520 N/A ARG 171.A NH1 ASP 168.A OD2 no hydrogen 2.786 N/A ARG 171.A NH2 ARG 148.A O no hydrogen 3.068 N/A ARG 172.A N VAL 169.A O no hydrogen 3.285 N/A ARG 172.A NH1 THR 213.A O no hydrogen 2.864 N/A ARG 173.A N ASP 168.A O no hydrogen 3.044 N/A ARG 173.A NE GLN 216.A OE1 no hydrogen 2.731 N/A ARG 173.A NH1 ASP 15.A OD2 no hydrogen 2.806 N/A ARG 173.A NH2 ASP 13.A OD2 no hydrogen 3.200 N/A ARG 173.A NH2 ASP 15.A OD1 no hydrogen 2.800 N/A ARG 173.A NH2 ASP 15.A OD2 no hydrogen 3.484 N/A ARG 173.A NH2 GLN 216.A OE1 no hydrogen 3.194 N/A LEU 174.A N GLN 216.A O no hydrogen 3.020 N/A PHE 175.A N PHE 166.A O no hydrogen 2.842 N/A CYS 176.A N ILE 218.A O no hydrogen 3.009 N/A CYS 176.A SG GLY 177.A O no hydrogen 3.992 N/A ASP 178.A N HIS 163.A NE2 no hydrogen 2.970 N/A ALA 179.A N CYS 176.A O no hydrogen 3.116 N/A GLY 181.A N ASP 178.A O no hydrogen 2.929 N/A GLU 182.A N ARG 191.A O no hydrogen 2.743 N/A ASP 184.A N VAL 189.A O no hydrogen 2.730 N/A GLU 185.A N GLN 272.A OE1 no hydrogen 2.853 N/A GLU 187.A N ASP 184.A OD1 no hydrogen 2.905 N/A GLY 188.A N ASP 184.A O no hydrogen 2.738 N/A ARG 191.A N GLU 182.A O no hydrogen 2.672 N/A ARG 191.A NE ASP 184.A OD2 no hydrogen 2.726 N/A ARG 191.A NH1 GLU 182.A OE1 no hydrogen 3.122 N/A ARG 191.A NH2 ASP 184.A OD2 no hydrogen 3.006 N/A LEU 193.A N TYR 201.A OH no hydrogen 3.286 N/A ASP 196.A N GLY 158.A O no hydrogen 2.997 N/A ASP 197.A N GLY 158.A O no hydrogen 3.045 N/A MET 198.A N GLN 296.A OE1 no hydrogen 2.954 N/A ALA 200.A N ASP 197.A OD1 no hydrogen 2.973 N/A TYR 201.A N ASP 197.A O no hydrogen 2.937 N/A LEU 202.A N MET 198.A O no hydrogen 2.934 N/A GLU 203.A N GLU 199.A O no hydrogen 3.013 N/A SER 204.A N ALA 200.A O no hydrogen 2.869 N/A SER 204.A OG HIS 157.A O no hydrogen 2.825 N/A SER 204.A OG ALA 200.A O no hydrogen 3.130 N/A LEU 205.A N TYR 201.A O no hydrogen 3.210 N/A GLU 206.A N LEU 202.A O no hydrogen 3.019 N/A ARG 207.A N GLU 203.A O no hydrogen 3.118 N/A ARG 207.A NE GLU 203.A OE1 no hydrogen 3.042 N/A ARG 207.A NE GLU 203.A OE2 no hydrogen 2.855 N/A ARG 207.A NH1 GLU 155.A O no hydrogen 2.696 N/A ARG 207.A NH2 GLU 155.A O no hydrogen 2.784 N/A ARG 207.A NH2 GLU 203.A OE1 no hydrogen 3.086 N/A LEU 208.A N SER 204.A O no hydrogen 2.841 N/A GLN 209.A N LEU 205.A O no hydrogen 2.900 N/A GLN 209.A NE2 LEU 205.A O no hydrogen 3.561 N/A ARG 210.A N ARG 207.A O no hydrogen 2.955 N/A LEU 211.A N LEU 208.A O no hydrogen 3.086 N/A LEU 215.A N ARG 172.A O no hydrogen 2.908 N/A GLN 216.A N ARG 172.A O no hydrogen 3.156 N/A GLN 216.A NE2 ASP 13.A OD2 no hydrogen 2.863 N/A LEU 217.A N LEU 225.A O no hydrogen 2.752 N/A ILE 218.A N LEU 174.A O no hydrogen 2.813 N/A GLY 220.A N GLY 177.A O no hydrogen 2.658 N/A HIS 221.A ND1 GLN 23.A O no hydrogen 2.733 N/A HIS 221.A NE2 HIS 76.A NE2 no hydrogen 3.026 N/A GLY 222.A N VAL 22.A O no hydrogen 2.913 N/A LEU 224.A N LEU 6.A O no hydrogen 2.810 N/A LEU 225.A N LEU 217.A O no hydrogen 2.794 N/A ARG 226.A N LEU 4.A O no hydrogen 2.970 N/A ARG 226.A NE MET 3.A O no hydrogen 2.866 N/A ARG 226.A NH2 MET 3.A O no hydrogen 2.778 N/A ALA 230.A N GLY 227.A O no hydrogen 3.185 N/A ALA 231.A N GLY 227.A O no hydrogen 3.100 N/A ASP 232.A N ARG 228.A O no hydrogen 2.798 N/A GLY 233.A N ALA 230.A O no hydrogen 3.276 N/A SER 236.A N ASP 232.A O no hydrogen 2.895 N/A SER 236.A OG ASP 232.A O no hydrogen 3.151 N/A ALA 237.A N GLY 233.A O no hydrogen 2.927 N/A TYR 238.A N ALA 234.A O no hydrogen 3.059 N/A TYR 238.A OH GLU 206.A OE2 no hydrogen 3.235 N/A THR 239.A N GLU 235.A O no hydrogen 2.946 N/A THR 239.A OG1 GLU 235.A O no hydrogen 3.206 N/A GLU 240.A N SER 236.A O no hydrogen 2.833 N/A CYS 241.A N ALA 237.A O no hydrogen 3.098 N/A LEU 242.A N TYR 238.A O no hydrogen 3.097 N/A ARG 243.A N THR 239.A O no hydrogen 2.915 N/A LEU 244.A N GLU 240.A O no hydrogen 2.988 N/A CYS 245.A N CYS 241.A O no hydrogen 3.029 N/A CYS 245.A SG CYS 241.A O no hydrogen 3.317 N/A ARG 246.A N LEU 242.A O no hydrogen 2.937 N/A ARG 247.A N ARG 243.A O no hydrogen 3.038 N/A LEU 248.A N LEU 244.A O no hydrogen 2.892 N/A LEU 249.A N CYS 245.A O no hydrogen 2.840 N/A TRP 250.A N ARG 246.A O no hydrogen 2.875 N/A ARG 251.A N ARG 247.A O no hydrogen 3.096 N/A ARG 251.A NH1 GLU 256.A OE1 no hydrogen 2.963 N/A GLN 252.A N LEU 248.A O no hydrogen 2.931 N/A GLN 252.A NE2 SER 294.A OG no hydrogen 3.154 N/A SER 253.A N LEU 249.A O no hydrogen 2.878 N/A SER 253.A OG LEU 249.A O no hydrogen 2.727 N/A MET 254.A N ARG 251.A O no hydrogen 2.913 N/A GLY 255.A N GLN 252.A O no hydrogen 2.784 N/A GLU 256.A N ARG 251.A O no hydrogen 3.132 N/A SER 257.A N GLU 260.A OE2 no hydrogen 3.176 N/A SER 257.A OG GLU 260.A OE2 no hydrogen 3.524 N/A GLU 260.A N SER 257.A O no hydrogen 2.944 N/A SER 262.A N LEU 258.A O no hydrogen 3.107 N/A SER 262.A OG LEU 258.A O no hydrogen 2.447 N/A GLU 263.A N ASP 259.A O no hydrogen 2.981 N/A GLU 264.A N GLU 260.A O no hydrogen 3.003 N/A LEU 265.A N LEU 261.A O no hydrogen 2.646 N/A HIS 266.A N SER 262.A O no hydrogen 2.833 N/A HIS 266.A ND1 HIS 282.A ND1 no hydrogen 2.841 N/A ARG 267.A N GLU 263.A O no hydrogen 2.871 N/A ALA 268.A N GLU 264.A O no hydrogen 2.810 N/A TRP 269.A N LEU 265.A O no hydrogen 2.695 N/A GLY 270.A N HIS 266.A O no hydrogen 2.667 N/A GLN 272.A NE2 PHE 183.A O no hydrogen 2.981 N/A PHE 276.A N SER 273.A O no hydrogen 3.085 N/A HIS 282.A N PRO 278.A O no hydrogen 3.106 N/A HIS 282.A ND1 HIS 266.A ND1 no hydrogen 2.841 N/A LEU 283.A N GLY 279.A O no hydrogen 3.095 N/A GLY 284.A N GLU 280.A O no hydrogen 2.809 N/A SER 285.A N LEU 281.A O no hydrogen 2.789 N/A SER 285.A OG LEU 281.A O no hydrogen 3.409 N/A MET 286.A N HIS 282.A O no hydrogen 2.871 N/A ARG 287.A N LEU 283.A O no hydrogen 2.935 N/A ARG 287.A NE ASP 259.A OD1 no hydrogen 2.823 N/A ARG 287.A NH2 ASP 259.A OD1 no hydrogen 3.061 N/A ARG 288.A N GLY 284.A O no hydrogen 2.856 N/A ARG 288.A NE PHE 195.A O no hydrogen 2.935 N/A MET 289.A N SER 285.A O no hydrogen 2.919 N/A LEU 290.A N MET 286.A O no hydrogen 3.026 N/A GLU 291.A N ARG 287.A O no hydrogen 2.921 N/A ILE 292.A N ARG 288.A O no hydrogen 2.930 N/A LEU 293.A N MET 289.A O no hydrogen 2.806 N/A SER 294.A N LEU 290.A O no hydrogen 2.735 N/A SER 294.A OG GLN 252.A OE1 no hydrogen 3.133 N/A ARG 295.A N GLU 291.A O no hydrogen 3.195 N/A GLN 296.A N ILE 292.A O no hydrogen 3.133 N/A GLN 296.A NE2 ASP 197.A OD1 no hydrogen 3.195 N/A