Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7uoo_n.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 8.A OG1 LYS 5.A O no hydrogen 2.776 N/A ARG 13.A N GLY 10.A O no hydrogen 3.286 N/A ASN 14.A N GLY 10.A O no hydrogen 2.904 N/A ILE 16.A N TYR 63.A O no hydrogen 2.909 N/A THR 17.A N GLN 20.A OE1 no hydrogen 3.349 N/A ALA 21.A N THR 17.A O no hydrogen 2.902 N/A VAL 22.A N ARG 18.A O no hydrogen 2.899 N/A ARG 23.A N SER 19.A O no hydrogen 2.934 N/A LYS 24.A N GLN 20.A O no hydrogen 2.883 N/A LYS 24.A NZ GLN 69.A OE1 no hydrogen 3.313 N/A LEU 25.A N ALA 21.A O no hydrogen 2.916 N/A GLN 26.A N VAL 22.A O no hydrogen 2.930 N/A ASP 31.A N SER 28.A OG no hydrogen 3.380 N/A PHE 32.A N SER 28.A O no hydrogen 2.933 N/A ARG 33.A N LEU 29.A O no hydrogen 2.915 N/A ARG 33.A NH1 ASP 214.A OD2 no hydrogen 3.458 N/A ARG 33.A NH2 ASP 214.A OD2 no hydrogen 2.812 N/A ARG 34.A N ALA 30.A O no hydrogen 2.995 N/A ARG 34.A NH2 ASP 31.A OD1 no hydrogen 3.515 N/A LEU 35.A N ASP 31.A O no hydrogen 2.897 N/A CYS 36.A N PHE 32.A O no hydrogen 2.920 N/A CYS 36.A SG PHE 32.A O no hydrogen 3.223 N/A ILE 37.A N ARG 33.A O no hydrogen 2.965 N/A PHE 38.A N ARG 34.A O no hydrogen 2.929 N/A LYS 39.A N LEU 35.A O no hydrogen 2.921 N/A LYS 39.A NZ GLU 74.A OE1 no hydrogen 2.679 N/A LYS 39.A NZ GLU 120.A OE1 no hydrogen 3.389 N/A LYS 39.A NZ GLU 120.A OE2 no hydrogen 3.409 N/A ILE 41.A N CYS 36.A O no hydrogen 2.903 N/A ARG 44.A N PHE 62.A O no hydrogen 2.775 N/A LYS 51.A N ASN 48.A OD1 no hydrogen 3.445 N/A ALA 52.A N ASN 48.A O no hydrogen 2.942 N/A ASN 53.A N LYS 49.A O no hydrogen 2.892 N/A GLY 55.A N LYS 50.A O no hydrogen 2.630 N/A SER 56.A N ASN 53.A O no hydrogen 3.290 N/A THR 60.A OG1 ALA 58.A O no hydrogen 3.126 N/A TYR 63.A N ILE 16.A O no hydrogen 2.906 N/A ALA 65.A N ASN 14.A O no hydrogen 3.124 N/A ILE 68.A N TYR 64.A O no hydrogen 3.003 N/A GLN 69.A N ALA 65.A O no hydrogen 2.911 N/A TYR 70.A N LYS 66.A O no hydrogen 2.899 N/A TYR 70.A OH GLU 120.A OE1 no hydrogen 3.043 N/A TYR 70.A OH GLU 120.A OE2 no hydrogen 3.056 N/A LEU 71.A N ASP 67.A O no hydrogen 2.907 N/A MET 72.A N ILE 68.A O no hydrogen 2.994 N/A MET 72.A N GLN 69.A O no hydrogen 3.216 N/A HIS 73.A N TYR 70.A O no hydrogen 3.156 N/A GLU 74.A N LEU 71.A O no hydrogen 3.330 N/A LEU 77.A N GLU 74.A O no hydrogen 3.092 N/A LYS 79.A N PRO 75.A O no hydrogen 2.955 N/A PHE 80.A N VAL 76.A O no hydrogen 2.878 N/A ARG 81.A N LEU 77.A O no hydrogen 2.992 N/A ARG 81.A NH1 GLN 26.A O no hydrogen 3.402 N/A ARG 81.A NH2 LEU 25.A O no hydrogen 3.363 N/A ARG 81.A NH2 GLN 26.A O no hydrogen 3.554 N/A GLU 82.A N ALA 78.A O no hydrogen 2.918 N/A HIS 83.A N LYS 79.A O no hydrogen 2.909 N/A LYS 84.A N PHE 80.A O no hydrogen 2.977 N/A THR 85.A N ARG 81.A O no hydrogen 3.003 N/A THR 85.A OG1 ARG 81.A O no hydrogen 3.269 N/A PHE 86.A N GLU 82.A O no hydrogen 2.912 N/A ALA 87.A N HIS 83.A O no hydrogen 2.869 N/A ARG 88.A N LYS 84.A O no hydrogen 3.025 N/A LYS 89.A N THR 85.A O no hydrogen 2.994 N/A LEU 90.A N PHE 86.A O no hydrogen 2.877 N/A THR 91.A N ALA 87.A O no hydrogen 2.932 N/A THR 91.A OG1 ALA 87.A O no hydrogen 2.709 N/A ARG 92.A N ARG 88.A O no hydrogen 2.965 N/A ALA 93.A N LYS 89.A O no hydrogen 2.971 N/A LEU 94.A N LEU 90.A O no hydrogen 2.947 N/A GLY 95.A N THR 91.A O no hydrogen 2.892 N/A ARG 96.A N ARG 92.A O no hydrogen 2.919 N/A ARG 96.A NE GLU 98.A OE2 no hydrogen 2.943 N/A GLY 97.A N LEU 94.A O no hydrogen 3.105 N/A GLU 98.A N ALA 93.A O no hydrogen 2.974 N/A ALA 102.A N GLU 98.A O no hydrogen 2.921 N/A LYS 103.A N VAL 99.A O no hydrogen 2.901 N/A ARG 104.A N SER 100.A O no hydrogen 2.952 N/A LEU 105.A N SER 101.A O no hydrogen 2.919 N/A GLU 106.A N ALA 102.A O no hydrogen 2.921 N/A GLU 107.A N LYS 103.A O no hydrogen 2.937 N/A ASN 108.A N ARG 104.A O no hydrogen 2.937 N/A TYR 112.A OH GLU 223.A OE1 no hydrogen 3.097 N/A HIS 116.A NE2 GLU 74.A OE2 no hydrogen 2.501 N/A ILE 118.A N LEU 114.A O no hydrogen 2.920 N/A LYS 119.A N ASP 115.A O no hydrogen 2.927 N/A GLU 120.A N HIS 116.A O no hydrogen 2.894 N/A ARG 121.A N ILE 117.A O no hydrogen 2.899 N/A ARG 121.A NH1 ILE 37.A O no hydrogen 3.358 N/A ARG 121.A NH1 PHE 38.A O no hydrogen 2.852 N/A TYR 122.A N ILE 118.A O no hydrogen 2.934 N/A TYR 122.A OH ASP 131.A OD2 no hydrogen 2.334 N/A SER 124.A OG ASP 127.A OD2 no hydrogen 3.450 N/A ALA 128.A N SER 124.A O no hydrogen 2.986 N/A ILE 129.A N PHE 125.A O no hydrogen 2.896 N/A ARG 130.A N PRO 126.A O no hydrogen 2.868 N/A ARG 130.A NE PRO 126.A O no hydrogen 3.153 N/A ASP 131.A N ASP 127.A O no hydrogen 2.974 N/A ASP 131.A N ALA 128.A O no hydrogen 3.102 N/A LEU 136.A N ILE 132.A O no hydrogen 2.893 N/A ASN 137.A N ASP 133.A O no hydrogen 2.973 N/A MET 138.A N ASP 134.A O no hydrogen 2.931 N/A LEU 139.A N ALA 135.A O no hydrogen 2.920 N/A PHE 140.A N LEU 136.A O no hydrogen 2.914 N/A LEU 141.A N ASN 137.A O no hydrogen 2.941 N/A PHE 142.A N MET 138.A O no hydrogen 2.921 N/A SER 143.A N LEU 139.A O no hydrogen 2.901 N/A SER 143.A OG LEU 139.A O no hydrogen 3.121 N/A SER 143.A OG PHE 140.A O no hydrogen 3.064 N/A ASN 144.A N LEU 141.A O no hydrogen 3.275 N/A ASN 144.A ND2 PHE 203.A O no hydrogen 2.655 N/A LEU 145.A N PHE 142.A O no hydrogen 3.406 N/A SER 147.A OG SER 153.A OG no hydrogen 2.800 N/A THR 148.A N VAL 151.A O no hydrogen 2.916 N/A VAL 151.A N THR 148.A OG1 no hydrogen 3.319 N/A SER 153.A OG SER 147.A OG no hydrogen 2.800 N/A ILE 156.A N SER 152.A O no hydrogen 2.994 N/A ASN 157.A N SER 153.A O no hydrogen 2.848 N/A ASP 158.A N LYS 154.A O no hydrogen 2.926 N/A ALA 159.A N ILE 155.A O no hydrogen 2.969 N/A GLN 160.A N ILE 156.A O no hydrogen 2.913 N/A LYS 161.A N ASN 157.A O no hydrogen 2.892 N/A ILE 162.A N ASP 158.A O no hydrogen 2.987 N/A CYS 163.A N ALA 159.A O no hydrogen 2.949 N/A CYS 163.A SG SER 143.A OG no hydrogen 3.775 N/A CYS 163.A SG ALA 159.A O no hydrogen 3.204 N/A ASN 164.A N GLN 160.A O no hydrogen 2.915 N/A GLN 165.A N LYS 161.A O no hydrogen 2.939 N/A TRP 166.A N ILE 162.A O no hydrogen 2.985 N/A LEU 167.A N CYS 163.A O no hydrogen 2.931 N/A ALA 168.A N ASN 164.A O no hydrogen 2.865 N/A TYR 169.A N GLN 165.A O no hydrogen 2.967 N/A VAL 170.A N TRP 166.A O no hydrogen 2.986 N/A ALA 171.A N LEU 167.A O no hydrogen 2.895 N/A LYS 172.A N ALA 168.A O no hydrogen 2.924 N/A GLU 173.A N TYR 169.A O no hydrogen 2.934 N/A ARG 174.A N VAL 170.A O no hydrogen 2.918 N/A ARG 174.A NE ALA 274.A O no hydrogen 3.319 N/A ARG 174.A NH2 ALA 274.A O no hydrogen 2.332 N/A VAL 176.A N SER 299.A OG no hydrogen 3.384 N/A ARG 177.A N GLN 189.A O no hydrogen 2.775 N/A ARG 177.A NH1 VAL 176.A O no hydrogen 2.481 N/A ARG 177.A NH2 ARG 174.A O no hydrogen 3.420 N/A LYS 178.A N GLN 189.A O no hydrogen 2.945 N/A LYS 178.A NZ ASN 346.A O no hydrogen 3.422 N/A VAL 179.A N ASN 346.A OD1 no hydrogen 3.176 N/A PHE 180.A N TYR 187.A O no hydrogen 2.933 N/A SER 182.A N GLY 185.A O no hydrogen 2.892 N/A SER 182.A OG GLY 185.A O no hydrogen 2.988 N/A LYS 184.A NZ TYR 187.A OH no hydrogen 3.431 N/A GLY 185.A N SER 182.A O no hydrogen 2.943 N/A VAL 186.A N VAL 201.A O no hydrogen 2.954 N/A TYR 187.A N PHE 180.A O no hydrogen 2.864 N/A TYR 188.A N TRP 199.A O no hydrogen 2.893 N/A GLN 189.A N LYS 178.A O no hydrogen 2.876 N/A GLN 189.A NE2 GLU 196.A OE1 no hydrogen 2.939 N/A ALA 190.A N VAL 197.A O no hydrogen 2.913 N/A ASN 191.A N LEU 175.A O no hydrogen 3.013 N/A ASN 191.A ND2 GLU 196.A OE2 no hydrogen 2.484 N/A ILE 192.A N GLU 195.A O no hydrogen 2.734 N/A GLU 195.A N ILE 192.A O no hydrogen 2.940 N/A VAL 197.A N ALA 190.A O no hydrogen 2.889 N/A TRP 199.A N TYR 188.A O no hydrogen 2.911 N/A LEU 200.A N ASN 137.A OD1 no hydrogen 2.965 N/A VAL 201.A N VAL 186.A O no hydrogen 2.884 N/A LYS 204.A NZ ASP 291.A OD2 no hydrogen 2.587 N/A PHE 205.A N PHE 203.A O no hydrogen 2.946 N/A SER 211.A OG PRO 210.A O no hydrogen 2.549 N/A MET 218.A N ASP 214.A O no hydrogen 2.995 N/A LEU 219.A N PHE 215.A O no hydrogen 2.810 N/A THR 220.A N ARG 216.A O no hydrogen 2.965 N/A THR 220.A OG1 ARG 216.A O no hydrogen 2.781 N/A PHE 221.A N ILE 217.A O no hydrogen 3.014 N/A LEU 222.A N MET 218.A O no hydrogen 2.853 N/A GLU 223.A N LEU 219.A O no hydrogen 2.895 N/A PHE 224.A N THR 220.A O no hydrogen 3.086 N/A TYR 225.A N PHE 221.A O no hydrogen 2.897 N/A SER 226.A N LEU 222.A O no hydrogen 2.848 N/A SER 226.A OG LEU 222.A O no hydrogen 2.800 N/A THR 227.A N GLU 223.A O no hydrogen 3.040 N/A THR 227.A OG1 GLU 223.A O no hydrogen 3.007 N/A LEU 228.A N PHE 224.A O no hydrogen 2.990 N/A LEU 229.A N TYR 225.A O no hydrogen 2.895 N/A HIS 230.A N SER 226.A O no hydrogen 2.905 N/A PHE 231.A N THR 227.A O no hydrogen 3.044 N/A VAL 232.A N LEU 228.A O no hydrogen 2.953 N/A LEU 233.A N LEU 229.A O no hydrogen 2.843 N/A TYR 234.A N HIS 230.A O no hydrogen 2.978 N/A LYS 235.A N PHE 231.A O no hydrogen 3.016 N/A LYS 235.A NZ ASP 239.A OD2 no hydrogen 3.238 N/A LEU 236.A N VAL 232.A O no hydrogen 2.901 N/A TYR 237.A N LEU 233.A O no hydrogen 2.922 N/A TYR 237.A OH GLN 165.A O no hydrogen 3.006 N/A THR 238.A N TYR 234.A O no hydrogen 2.972 N/A THR 238.A OG1 TYR 234.A O no hydrogen 2.783 N/A THR 238.A OG1 LYS 235.A O no hydrogen 2.763 N/A THR 238.A OG1 ASP 239.A OD1 no hydrogen 3.524 N/A ASP 239.A N LYS 235.A O no hydrogen 2.882 N/A SER 240.A N LEU 236.A O no hydrogen 2.933 N/A SER 240.A OG GLU 173.A OE2 no hydrogen 2.605 N/A GLY 241.A N THR 238.A O no hydrogen 3.054 N/A LEU 242.A N TYR 237.A O no hydrogen 2.761 N/A ILE 243.A N GLU 265.A O no hydrogen 3.259 N/A TYR 244.A OH GLN 165.A OE1 no hydrogen 2.586 N/A TYR 244.A OH HIS 230.A ND1 no hydrogen 3.357 N/A ASP 249.A N SER 261.A O no hydrogen 3.010 N/A ASP 253.A N ASP 249.A O no hydrogen 2.912 N/A LYS 254.A N LEU 250.A O no hydrogen 2.905 N/A ILE 255.A N LYS 251.A O no hydrogen 2.927 N/A ILE 256.A N LYS 252.A O no hydrogen 2.910 N/A SER 257.A OG ASP 253.A OD1 no hydrogen 2.914 N/A SER 261.A N GLY 258.A O no hydrogen 3.494 N/A SER 261.A OG ASP 253.A OD1 no hydrogen 3.084 N/A ILE 263.A N LYS 247.A O no hydrogen 3.315 N/A SER 266.A OG GLY 241.A O no hydrogen 3.310 N/A ARG 267.A N GLY 241.A O no hydrogen 3.284 N/A SER 275.A OG PRO 272.A O no hydrogen 3.012 N/A LEU 276.A N VAL 273.A O no hydrogen 3.291 N/A SER 278.A N SER 275.A O no hydrogen 3.372 N/A SER 278.A OG SER 275.A O no hydrogen 3.077 N/A VAL 281.A N THR 317.A OG1 no hydrogen 3.264 N/A PHE 282.A N ASN 303.A O no hydrogen 2.862 N/A TYR 283.A N HIS 318.A O no hydrogen 2.861 N/A VAL 284.A N ILE 305.A O no hydrogen 2.906 N/A SER 285.A N ILE 320.A O no hydrogen 2.919 N/A SER 285.A OG GLU 287.A OE2 no hydrogen 2.665 N/A SER 285.A OG GLU 307.A OE1 no hydrogen 3.416 N/A LEU 293.A N PRO 289.A O no hydrogen 2.999 N/A GLU 294.A N ILE 290.A O no hydrogen 2.831 N/A PHE 295.A N ASP 291.A O no hydrogen 2.946 N/A LEU 296.A N ILE 292.A O no hydrogen 2.985 N/A ILE 297.A N LEU 293.A O no hydrogen 2.917 N/A LEU 298.A N GLU 294.A O no hydrogen 2.899 N/A SER 299.A N PHE 295.A O no hydrogen 2.936 N/A CYS 300.A N LEU 296.A O no hydrogen 2.906 N/A CYS 300.A SG VAL 273.A O no hydrogen 3.260 N/A ASN 303.A N PHE 280.A O no hydrogen 2.942 N/A ILE 305.A N PHE 282.A O no hydrogen 2.920 N/A GLU 307.A N VAL 284.A O no hydrogen 3.177 N/A MET 310.A N GLU 307.A O no hydrogen 3.389 N/A LYS 315.A N SER 314.A OG no hydrogen 2.576 N/A THR 317.A N VAL 281.A O no hydrogen 3.005 N/A THR 317.A OG1 VAL 281.A O no hydrogen 3.251 N/A THR 317.A OG1 HIS 318.A ND1 no hydrogen 2.542 N/A HIS 318.A N VAL 281.A O no hydrogen 2.943 N/A HIS 318.A ND1 THR 317.A OG1 no hydrogen 2.542 N/A GLN 319.A N THR 334.A O no hydrogen 2.867 N/A ILE 320.A N TYR 283.A O no hydrogen 2.913 N/A VAL 321.A N ILE 336.A O no hydrogen 2.907 N/A ARG 323.A NE GLU 287.A OE1 no hydrogen 2.917 N/A VAL 330.A N TYR 335.A OH no hydrogen 2.818 N/A ARG 333.A N VAL 330.A O no hydrogen 3.274 N/A ARG 333.A NH1 GLN 319.A OE1 no hydrogen 2.972 N/A THR 334.A N THR 317.A O no hydrogen 2.907 N/A ILE 336.A N GLN 319.A O no hydrogen 2.928 N/A GLN 337.A NE2 LEU 357.A O no hydrogen 2.422 N/A GLN 339.A NE2 ASP 343.A OD2 no hydrogen 3.191 N/A GLN 339.A NE2 PRO 363.A O no hydrogen 2.672 N/A TRP 340.A N GLN 337.A O no hydrogen 3.172 N/A TRP 340.A NE1 VAL 351.A O no hydrogen 2.843 N/A ILE 341.A N PRO 338.A O no hydrogen 3.234 N/A ASP 343.A N GLN 339.A O no hydrogen 2.922 N/A CYS 344.A N TRP 340.A O no hydrogen 2.886 N/A CYS 344.A SG TRP 340.A O no hydrogen 3.209 N/A CYS 344.A SG VAL 351.A O no hydrogen 3.797 N/A ILE 345.A N ILE 341.A O no hydrogen 2.958 N/A ASN 346.A N PHE 342.A O no hydrogen 2.941 N/A ASN 346.A ND2 VAL 179.A O no hydrogen 2.646 N/A LYS 347.A N ASP 343.A O no hydrogen 2.882 N/A GLY 348.A N CYS 344.A O no hydrogen 2.917 N/A TYR 356.A N ALA 353.A O no hydrogen 3.412 N/A TYR 356.A OH ASP 343.A OD2 no hydrogen 2.756 N/A GLU 360.A N LEU 357.A O no hydrogen 3.385 N/A TRP 369.A NE1 GLN 189.A OE1 no hydrogen 2.600 N/A