Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7vfa_E.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A N GLN 295.A OE1 no hydrogen 2.944 N/A PHE 8.A N SER 113.A OG no hydrogen 2.837 N/A SER 10.A OG GLU 14.A OE1 no hydrogen 2.524 N/A VAL 13.A N SER 10.A O no hydrogen 2.989 N/A GLU 14.A N SER 10.A O no hydrogen 2.795 N/A GLY 15.A N GLY 11.A O no hydrogen 3.107 N/A CYS 16.A N VAL 13.A O no hydrogen 2.864 N/A CYS 16.A SG LYS 12.A O no hydrogen 3.459 N/A CYS 16.A SG TRP 31.A O no hydrogen 3.490 N/A MET 17.A N GLU 14.A O no hydrogen 3.200 N/A VAL 18.A N GLY 29.A O no hydrogen 2.978 N/A GLN 19.A N GLN 69.A O no hydrogen 2.909 N/A VAL 20.A N LEU 27.A O no hydrogen 2.894 N/A THR 21.A N LEU 67.A O no hydrogen 2.797 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 2.685 N/A CYS 22.A N THR 25.A O no hydrogen 2.913 N/A CYS 22.A SG ASN 65.A O no hydrogen 3.681 N/A THR 25.A N CYS 22.A O no hydrogen 3.171 N/A THR 25.A OG1 CYS 44.A O no hydrogen 3.023 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 2.685 N/A LEU 27.A N VAL 20.A O no hydrogen 3.002 N/A ASN 28.A N CYS 145.A O no hydrogen 3.010 N/A ASN 28.A ND2 CYS 117.A O no hydrogen 2.943 N/A ASN 28.A ND2 CYS 145.A O no hydrogen 2.951 N/A GLY 29.A N VAL 18.A O no hydrogen 2.804 N/A LEU 30.A N TYR 37.A O no hydrogen 2.834 N/A TRP 31.A N CYS 16.A O no hydrogen 2.715 N/A TRP 31.A NE1 THR 93.A O no hydrogen 3.130 N/A LEU 32.A N VAL 35.A O no hydrogen 2.950 N/A ASP 33.A N THR 98.A OG1 no hydrogen 3.002 N/A VAL 35.A N LEU 32.A O no hydrogen 3.036 N/A VAL 36.A N LEU 89.A O no hydrogen 2.801 N/A TYR 37.A N LEU 30.A O no hydrogen 2.840 N/A CYS 38.A N LEU 87.A O no hydrogen 3.091 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.642 N/A ARG 40.A N CYS 85.A O no hydrogen 2.966 N/A ARG 40.A NE ASP 187.A OD2 no hydrogen 2.727 N/A ARG 40.A NH2 ASP 187.A OD1 no hydrogen 3.029 N/A ARG 40.A NH2 ASP 187.A OD2 no hydrogen 3.567 N/A HIS 41.A NE2 HIS 164.A O no hydrogen 2.861 N/A VAL 42.A N PRO 39.A O no hydrogen 3.044 N/A ILE 43.A N ARG 40.A O no hydrogen 3.214 N/A CYS 44.A N HIS 41.A O no hydrogen 2.952 N/A THR 45.A N ASP 48.A OD1 no hydrogen 3.024 N/A ASP 48.A N THR 45.A OG1 no hydrogen 3.121 N/A MET 49.A N THR 45.A O no hydrogen 3.281 N/A MET 49.A N SER 46.A O no hydrogen 3.137 N/A LEU 50.A N GLU 47.A O no hydrogen 3.109 N/A TYR 54.A OH ASP 187.A O no hydrogen 2.700 N/A GLU 55.A N GLU 55.A OE1 no hydrogen 2.701 N/A ASP 56.A N ASN 53.A OD1 no hydrogen 2.935 N/A LEU 57.A N ASN 53.A O no hydrogen 2.855 N/A LEU 58.A N TYR 54.A O no hydrogen 2.862 N/A ILE 59.A N GLU 55.A O no hydrogen 3.106 N/A ARG 60.A N LEU 57.A O no hydrogen 3.276 N/A LYS 61.A N LEU 58.A O no hydrogen 2.984 N/A SER 62.A N ASN 65.A OD1 no hydrogen 2.792 N/A ASN 65.A N SER 62.A O no hydrogen 2.971 N/A PHE 66.A N ASN 63.A O no hydrogen 3.069 N/A LEU 67.A N THR 21.A O no hydrogen 2.824 N/A GLN 69.A N GLN 19.A O no hydrogen 2.819 N/A GLN 69.A NE2 GLY 71.A O no hydrogen 2.697 N/A ALA 70.A N VAL 73.A O no hydrogen 2.648 N/A VAL 73.A N ALA 70.A O no hydrogen 3.054 N/A LEU 75.A N VAL 68.A O no hydrogen 2.760 N/A ILE 78.A N LYS 90.A O no hydrogen 2.726 N/A HIS 80.A ND1 ASN 63.A OD1 no hydrogen 2.678 N/A SER 81.A N LYS 88.A O no hydrogen 2.995 N/A GLN 83.A N VAL 86.A O no hydrogen 2.895 N/A ASN 84.A ND2 GLU 178.A O no hydrogen 2.762 N/A CYS 85.A N GLY 179.A O no hydrogen 2.861 N/A CYS 85.A SG ASP 187.A OD2 no hydrogen 3.836 N/A VAL 86.A N GLN 83.A O no hydrogen 2.920 N/A LEU 87.A N CYS 38.A O no hydrogen 2.754 N/A LYS 88.A N SER 81.A O no hydrogen 2.836 N/A LYS 88.A NZ GLN 83.A OE1 no hydrogen 3.171 N/A LEU 89.A N VAL 36.A O no hydrogen 2.822 N/A LYS 90.A N GLY 79.A O no hydrogen 2.810 N/A LYS 90.A NZ ASP 34.A OD1 no hydrogen 2.830 N/A VAL 91.A N ASP 34.A O no hydrogen 2.836 N/A ASP 92.A N ARG 76.A O no hydrogen 2.993 N/A THR 93.A OG1 ASP 92.A OD1 no hydrogen 3.001 N/A ASN 95.A N ASP 33.A O no hydrogen 2.837 N/A ASN 95.A ND2 GLY 15.A O no hydrogen 3.147 N/A ASN 95.A ND2 TRP 31.A O no hydrogen 2.941 N/A LYS 97.A N ASN 95.A OD1 no hydrogen 2.929 N/A THR 98.A N ASN 95.A O no hydrogen 3.116 N/A THR 98.A OG1 ASN 95.A O no hydrogen 2.627 N/A TYR 101.A OH ASP 33.A OD2 no hydrogen 3.192 N/A LYS 102.A N VAL 157.A O no hydrogen 3.029 N/A VAL 104.A N PHE 159.A O no hydrogen 2.898 N/A ARG 105.A NH1 ASP 176.A OD2 no hydrogen 2.823 N/A ARG 105.A NH1 ASN 180.A O no hydrogen 3.018 N/A ARG 105.A NH2 PHE 181.A O no hydrogen 2.921 N/A ILE 106.A N TYR 182.A OH no hydrogen 3.078 N/A GLN 107.A N GLN 110.A OE1 no hydrogen 2.981 N/A GLY 109.A N MET 130.A O no hydrogen 2.558 N/A GLN 110.A N GLN 107.A O no hydrogen 3.126 N/A THR 111.A OG1 ASP 291.A OD1 no hydrogen 3.308 N/A THR 111.A OG1 ASP 291.A OD2 no hydrogen 2.641 N/A PHE 112.A N CYS 128.A O no hydrogen 2.862 N/A SER 113.A N PHE 150.A O no hydrogen 2.918 N/A SER 113.A OG GLN 127.A OE1 no hydrogen 2.716 N/A VAL 114.A N TYR 126.A O no hydrogen 2.734 N/A LEU 115.A N VAL 148.A O no hydrogen 3.232 N/A ALA 116.A N GLY 124.A O no hydrogen 2.828 N/A CYS 117.A N SER 147.A OG no hydrogen 2.930 N/A CYS 117.A SG LEU 115.A O no hydrogen 3.553 N/A TYR 118.A N SER 121.A O no hydrogen 2.823 N/A GLY 120.A N ASN 28.A OD1 no hydrogen 2.494 N/A SER 121.A N TYR 118.A O no hydrogen 2.851 N/A SER 123.A N ALA 116.A O no hydrogen 2.701 N/A SER 123.A OG ALA 116.A O no hydrogen 3.480 N/A SER 123.A OG SER 121.A O no hydrogen 3.373 N/A GLY 124.A N ALA 116.A O no hydrogen 3.319 N/A TYR 126.A N VAL 114.A O no hydrogen 2.908 N/A CYS 128.A N PHE 112.A O no hydrogen 2.749 N/A CYS 128.A SG TYR 126.A O no hydrogen 3.779 N/A MET 130.A N GLN 110.A O no hydrogen 2.980 N/A ARG 131.A NE ASP 197.A OD2 no hydrogen 2.837 N/A ARG 131.A NH1 ASP 285.A OD1 no hydrogen 3.054 N/A ARG 131.A NH1 ASP 285.A OD2 no hydrogen 3.458 N/A ARG 131.A NH1 GLU 286.A OE2 no hydrogen 2.854 N/A ARG 131.A NH2 ASP 197.A OD2 no hydrogen 3.498 N/A ARG 131.A NH2 THR 198.A O no hydrogen 3.024 N/A ARG 131.A NH2 ASP 285.A OD2 no hydrogen 2.835 N/A ASN 133.A N ASP 197.A OD1 no hydrogen 3.267 N/A ASN 133.A ND2 GLY 195.A O no hydrogen 2.960 N/A PHE 134.A N ARG 131.A O no hydrogen 2.807 N/A THR 135.A N ASN 133.A OD1 no hydrogen 3.152 N/A THR 135.A OG1 ASN 133.A OD1 no hydrogen 2.694 N/A ILE 136.A N HIS 172.A O no hydrogen 3.176 N/A ASN 142.A N SER 139.A O no hydrogen 2.969 N/A ASN 142.A ND2 GLU 166.A OE1 no hydrogen 2.557 N/A SER 144.A N LEU 141.A O no hydrogen 3.087 N/A SER 144.A OG CYS 117.A O no hydrogen 3.364 N/A SER 144.A OG PHE 140.A O no hydrogen 3.257 N/A SER 144.A OG ASN 142.A O no hydrogen 3.395 N/A CYS 145.A SG HIS 164.A O no hydrogen 3.087 N/A GLY 146.A N HIS 163.A O no hydrogen 2.838 N/A SER 147.A N SER 144.A O no hydrogen 3.124 N/A SER 147.A OG LEU 115.A O no hydrogen 3.375 N/A SER 147.A OG SER 144.A O no hydrogen 2.873 N/A GLY 149.A N TYR 161.A O no hydrogen 2.807 N/A PHE 150.A N SER 113.A O no hydrogen 2.845 N/A ASN 151.A N SER 158.A O no hydrogen 2.945 N/A ASN 151.A ND2 THR 111.A O no hydrogen 2.984 N/A ASP 153.A N CYS 156.A O no hydrogen 2.946 N/A CYS 156.A N ASP 153.A O no hydrogen 2.989 N/A VAL 157.A N LYS 100.A O no hydrogen 2.889 N/A SER 158.A N ASN 151.A O no hydrogen 2.781 N/A PHE 159.A N LYS 102.A O no hydrogen 2.880 N/A CYS 160.A N GLY 149.A O no hydrogen 3.026 N/A MET 162.A N THR 175.A O no hydrogen 2.829 N/A HIS 163.A N SER 147.A O no hydrogen 2.819 N/A HIS 163.A NE2 HIS 172.A ND1 no hydrogen 2.991 N/A HIS 164.A N ALA 173.A O no hydrogen 3.008 N/A MET 165.A N ALA 173.A O no hydrogen 3.129 N/A LEU 167.A N VAL 171.A O no hydrogen 2.832 N/A GLY 170.A N LEU 167.A O no hydrogen 2.883 N/A HIS 172.A N ILE 136.A O no hydrogen 2.798 N/A HIS 172.A ND1 HIS 163.A NE2 no hydrogen 2.991 N/A HIS 172.A NE2 GLY 138.A O no hydrogen 2.724 N/A ALA 173.A N MET 165.A O no hydrogen 2.906 N/A THR 175.A N MET 162.A O no hydrogen 2.994 N/A THR 175.A OG1 HIS 164.A NE2 no hydrogen 2.915 N/A THR 175.A OG1 ASP 176.A O no hydrogen 2.779 N/A ASP 176.A N ASN 180.A O no hydrogen 3.066 N/A GLY 179.A N ASP 176.A O no hydrogen 2.989 N/A ASN 180.A N ASP 176.A OD1 no hydrogen 3.003 N/A TYR 182.A N GLY 174.A O no hydrogen 2.919 N/A TYR 182.A OH CYS 160.A O no hydrogen 2.600 N/A PHE 185.A N GLY 183.A O no hydrogen 2.914 N/A VAL 186.A N GLN 192.A OE1 no hydrogen 2.803 N/A ARG 188.A NE LEU 50.A O no hydrogen 3.126 N/A ARG 188.A NH2 ASN 51.A OD1 no hydrogen 3.284 N/A GLN 189.A N MET 49.A O no hydrogen 2.654 N/A GLN 192.A NE2 VAL 186.A O no hydrogen 3.103 N/A GLN 192.A NE2 THR 190.A O no hydrogen 3.436 N/A THR 198.A OG1 GLU 236.A OE2 no hydrogen 2.415 N/A THR 199.A N ASN 234.A O no hydrogen 3.144 N/A ILE 200.A N ASP 285.A OD2 no hydrogen 2.849 N/A THR 201.A OG1 GLU 236.A O no hydrogen 2.482 N/A ASN 203.A N ILE 200.A O no hydrogen 3.140 N/A ASN 203.A ND2 GLY 109.A O no hydrogen 2.822 N/A ASN 203.A ND2 ASP 285.A O no hydrogen 3.029 N/A VAL 204.A N ILE 200.A O no hydrogen 3.105 N/A LEU 205.A N THR 201.A O no hydrogen 3.073 N/A ALA 206.A N VAL 202.A O no hydrogen 3.137 N/A TRP 207.A N ASN 203.A O no hydrogen 2.924 N/A LEU 208.A N VAL 204.A O no hydrogen 2.850 N/A TYR 209.A N LEU 205.A O no hydrogen 2.913 N/A TYR 209.A OH ILE 255.A O no hydrogen 2.909 N/A ALA 210.A N ALA 206.A O no hydrogen 2.893 N/A ALA 211.A N TRP 207.A O no hydrogen 2.799 N/A VAL 212.A N LEU 208.A O no hydrogen 2.962 N/A VAL 212.A N TYR 209.A O no hydrogen 3.038 N/A ILE 213.A N TYR 209.A O no hydrogen 3.030 N/A GLY 215.A N VAL 212.A O no hydrogen 3.157 N/A ASP 216.A N ALA 211.A O no hydrogen 2.713 N/A ASP 225.A N THR 222.A OG1 no hydrogen 3.304 N/A PHE 226.A N THR 222.A O no hydrogen 3.178 N/A ASN 227.A N LEU 223.A O no hydrogen 3.027 N/A ASN 227.A ND2 LEU 238.A O no hydrogen 2.880 N/A LEU 228.A N ASN 224.A O no hydrogen 3.109 N/A VAL 229.A N PHE 226.A O no hydrogen 2.831 N/A ALA 230.A N PHE 226.A O no hydrogen 2.785 N/A MET 231.A N ASN 227.A O no hydrogen 2.920 N/A LYS 232.A N VAL 229.A O no hydrogen 3.138 N/A TYR 233.A N ALA 230.A O no hydrogen 3.021 N/A GLU 236.A N THR 199.A O no hydrogen 2.899 N/A LEU 238.A N ASN 227.A OD1 no hydrogen 2.668 N/A THR 239.A N HIS 242.A ND1 no hydrogen 3.064 N/A HIS 242.A N THR 239.A OG1 no hydrogen 3.091 N/A VAL 243.A N THR 239.A O no hydrogen 3.250 N/A ASP 244.A N GLN 240.A O no hydrogen 3.129 N/A ILE 245.A N ASP 241.A O no hydrogen 3.006 N/A LEU 246.A N HIS 242.A O no hydrogen 3.074 N/A GLY 247.A N ASP 244.A O no hydrogen 3.080 N/A SER 250.A N LEU 246.A O no hydrogen 2.803 N/A SER 250.A OG ILE 255.A O no hydrogen 2.444 N/A ALA 251.A N GLY 247.A O no hydrogen 2.725 N/A GLN 252.A N PRO 248.A O no hydrogen 3.074 N/A GLN 252.A NE2 CYS 296.A O no hydrogen 3.060 N/A THR 253.A N LEU 249.A O no hydrogen 3.146 N/A THR 253.A OG1 LEU 249.A O no hydrogen 2.991 N/A GLY 254.A N ALA 251.A O no hydrogen 3.273 N/A ILE 255.A N THR 253.A OG1 no hydrogen 3.374 N/A MET 260.A N ALA 256.A O no hydrogen 2.841 N/A CYS 261.A N VAL 257.A O no hydrogen 2.759 N/A CYS 261.A SG VAL 257.A O no hydrogen 3.182 N/A ALA 262.A N LEU 258.A O no hydrogen 2.956 N/A SER 263.A N ASP 259.A O no hydrogen 3.108 N/A SER 263.A OG ASP 259.A O no hydrogen 3.354 N/A LEU 264.A N MET 260.A O no hydrogen 2.960 N/A LYS 265.A N CYS 261.A O no hydrogen 2.999 N/A LYS 265.A N ALA 262.A O no hydrogen 3.295 N/A GLN 269.A NE2 TYR 233.A OH no hydrogen 3.500 N/A ASN 270.A N GLU 266.A O no hydrogen 3.216 N/A ARG 275.A N MET 272.A O no hydrogen 3.298 N/A THR 276.A OG1 SER 280.A O no hydrogen 3.029 N/A ILE 277.A N SER 280.A O no hydrogen 2.571 N/A LEU 278.A N ASP 216.A OD2 no hydrogen 3.324 N/A SER 280.A N ILE 277.A O no hydrogen 3.001 N/A SER 280.A OG LEU 282.A O no hydrogen 2.881 N/A LEU 282.A N SER 280.A OG no hydrogen 3.211 N/A GLU 286.A N GLU 284.A OE2 no hydrogen 3.019 N/A THR 288.A N ASP 291.A OD2 no hydrogen 3.146 N/A ASP 291.A N THR 288.A OG1 no hydrogen 2.954 N/A VAL 292.A N THR 288.A O no hydrogen 3.169 N/A VAL 293.A N PRO 289.A O no hydrogen 3.152 N/A ARG 294.A N PHE 290.A O no hydrogen 2.794 N/A GLN 295.A N ASP 291.A O no hydrogen 3.292 N/A GLN 295.A N VAL 292.A O no hydrogen 3.084 N/A GLN 295.A NE2 ARG 4.A O no hydrogen 2.745 N/A CYS 296.A N VAL 292.A O no hydrogen 2.710 N/A