Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7vkm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N GLU 67.A OE1 no hydrogen 3.250 N/A HIS 8.A ND1 HIS 9.A O no hydrogen 2.889 N/A HIS 9.A ND1 VAL 7.A O no hydrogen 2.880 N/A ILE 10.A N VAL 83.A O no hydrogen 2.744 N/A ARG 12.A N GLU 86.A OE2 no hydrogen 3.257 N/A ARG 12.A NE ARG 12.A O no hydrogen 2.739 N/A ARG 12.A NH1 ILE 15.A O no hydrogen 2.655 N/A ASP 14.A N LYS 11.A O no hydrogen 2.880 N/A ILE 15.A N ARG 12.A O no hydrogen 3.184 N/A VAL 16.A N GLU 33.A O no hydrogen 2.955 N/A LYS 18.A N LEU 31.A O no hydrogen 2.847 N/A LEU 21.A N VAL 29.A O no hydrogen 2.785 N/A GLY 22.A N VAL 29.A O no hydrogen 3.206 N/A GLY 24.A N GLY 27.A O no hydrogen 3.198 N/A ALA 25.A N ASP 179.A OD2 no hydrogen 3.073 N/A LYS 28.A N ALA 50.A O no hydrogen 2.991 N/A VAL 29.A N GLY 22.A O no hydrogen 2.879 N/A PHE 30.A N VAL 48.A O no hydrogen 2.978 N/A LEU 31.A N TRP 19.A O no hydrogen 2.941 N/A ALA 32.A N VAL 46.A O no hydrogen 2.940 N/A GLU 33.A N VAL 16.A O no hydrogen 2.948 N/A CYS 34.A N MET 44.A O no hydrogen 2.837 N/A CYS 34.A SG ASP 14.A O no hydrogen 3.321 N/A HIS 35.A N ASP 14.A O no hydrogen 2.743 N/A ASN 36.A N ASP 42.A O no hydrogen 2.548 N/A VAL 46.A N ALA 32.A O no hydrogen 2.698 N/A ALA 47.A N PHE 94.A O no hydrogen 2.947 N/A VAL 48.A N PHE 30.A O no hydrogen 3.013 N/A LYS 49.A N MET 92.A O no hydrogen 2.619 N/A ALA 50.A N LYS 28.A O no hydrogen 2.783 N/A LEU 51.A N LEU 90.A O no hydrogen 2.871 N/A LYS 52.A NZ ALA 25.A O no hydrogen 2.594 N/A SER 55.A OG GLU 53.A OE1.A no hydrogen 2.290 N/A SER 55.A OG SER 57.A OG no hydrogen 3.193 N/A SER 57.A OG SER 55.A OG no hydrogen 3.193 N/A ARG 59.A N SER 55.A O no hydrogen 2.829 N/A GLN 60.A N GLU 56.A O no hydrogen 3.134 N/A ASP 61.A N SER 57.A O no hydrogen 3.212 N/A PHE 62.A N ALA 58.A O no hydrogen 2.814 N/A GLN 63.A N ARG 59.A O no hydrogen 3.117 N/A ARG 64.A N GLN 60.A O no hydrogen 3.012 N/A GLU 65.A N ASP 61.A O no hydrogen 2.640 N/A ALA 66.A N PHE 62.A O no hydrogen 2.856 N/A GLU 67.A N GLN 63.A O no hydrogen 2.887 N/A LEU 68.A N ARG 64.A O no hydrogen 2.985 N/A LEU 69.A N GLU 65.A O no hydrogen 2.795 N/A THR 70.A N ALA 66.A O no hydrogen 2.733 N/A THR 70.A OG1 ALA 66.A O no hydrogen 2.310 N/A MET 71.A N GLU 67.A O no hydrogen 2.991 N/A LEU 72.A N LEU 68.A O no hydrogen 3.215 N/A GLN 73.A N TYR 145.A OH no hydrogen 3.116 N/A GLN 73.A NE2 LEU 72.A O no hydrogen 2.691 N/A HIS 76.A ND1 VAL 169.A O no hydrogen 3.011 N/A ILE 77.A N HIS 74.A O no hydrogen 3.184 N/A VAL 78.A N ILE 171.A O no hydrogen 3.159 N/A ARG 79.A N GLU 95.A OE1 no hydrogen 2.945 N/A PHE 81.A N VAL 93.A O no hydrogen 2.952 N/A VAL 83.A N HIS 8.A O no hydrogen 3.184 N/A CYS 84.A N LEU 91.A O no hydrogen 3.115 N/A CYS 84.A SG ILE 10.A O no hydrogen 3.443 N/A THR 85.A OG1 HIS 9.A NE2 no hydrogen 3.127 N/A GLY 87.A N THR 85.A O no hydrogen 2.949 N/A LEU 91.A N CYS 84.A O no hydrogen 3.320 N/A MET 92.A N LYS 49.A O no hydrogen 2.834 N/A VAL 93.A N GLY 82.A O no hydrogen 3.130 N/A PHE 94.A N ALA 47.A O no hydrogen 2.711 N/A GLU 95.A N ARG 79.A O no hydrogen 3.082 N/A ARG 98.A NH1 GLU 120.A OE1 no hydrogen 3.244 N/A ARG 98.A NH2 GLU 120.A OE1 no hydrogen 3.179 N/A HIS 99.A N VAL 163.A O no hydrogen 3.004 N/A HIS 99.A NE2 ASP 121.A OD2 no hydrogen 2.758 N/A ARG 100.A N MET 97.A O no hydrogen 3.202 N/A ARG 100.A NH2 LEU 21.A O no hydrogen 3.292 N/A LEU 102.A N CYS 161.A O no hydrogen 2.841 N/A ASN 103.A ND2 THR 158.A OG1 no hydrogen 3.109 N/A ASN 103.A ND2 GLU 224.A OE1 no hydrogen 3.461 N/A ASN 103.A ND2 GLY 229.A O no hydrogen 2.844 N/A ARG 104.A N ASP 101.A OD1 no hydrogen 2.784 N/A PHE 105.A N ASP 101.A O no hydrogen 3.043 N/A LEU 106.A N LEU 102.A O no hydrogen 2.935 N/A ARG 107.A N ASN 103.A O no hydrogen 3.057 N/A ARG 107.A NH1 ASN 103.A OD1 no hydrogen 3.413 N/A SER 108.A N ARG 104.A O no hydrogen 3.153 N/A SER 108.A OG PHE 105.A O no hydrogen 2.696 N/A HIS 109.A N LEU 106.A O no hydrogen 2.943 N/A HIS 109.A ND1 GLY 125.A O no hydrogen 3.194 N/A GLY 110.A N ARG 107.A O no hydrogen 3.302 N/A LEU 127.A N TYR 228.A OH no hydrogen 2.832 N/A GLY 128.A N GLN 131.A OE1 no hydrogen 2.931 N/A GLN 131.A N GLY 128.A O no hydrogen 2.531 N/A LEU 132.A N GLY 128.A O no hydrogen 2.999 N/A LEU 133.A N LEU 129.A O no hydrogen 2.953 N/A ALA 134.A N GLY 130.A O no hydrogen 3.130 N/A VAL 135.A N GLN 131.A O no hydrogen 2.842 N/A ALA 136.A N LEU 132.A O no hydrogen 2.973 N/A SER 137.A N LEU 133.A O no hydrogen 2.944 N/A GLN 138.A N ALA 134.A O no hydrogen 3.128 N/A GLN 138.A N VAL 135.A O no hydrogen 3.053 N/A GLN 138.A NE2 ALA 134.A O no hydrogen 3.190 N/A GLN 138.A NE2 LEU 167.A O no hydrogen 3.110 N/A VAL 139.A N VAL 135.A O no hydrogen 3.149 N/A ALA 140.A N ALA 136.A O no hydrogen 3.133 N/A ALA 141.A N SER 137.A O no hydrogen 2.900 N/A GLY 142.A N GLN 138.A O no hydrogen 3.097 N/A MET 143.A N VAL 139.A O no hydrogen 2.945 N/A VAL 144.A N ALA 140.A O no hydrogen 2.963 N/A TYR 145.A N ALA 141.A O no hydrogen 3.297 N/A LEU 146.A N GLY 142.A O no hydrogen 3.064 N/A ALA 147.A N MET 143.A O no hydrogen 2.719 N/A GLY 148.A N VAL 144.A O no hydrogen 2.856 N/A LEU 149.A N LEU 146.A O no hydrogen 3.115 N/A HIS 150.A N ALA 147.A O no hydrogen 2.861 N/A PHE 151.A N LEU 146.A O no hydrogen 2.966 N/A HIS 153.A N ASP 214.A OD2 no hydrogen 2.744 N/A ARG 154.A N ASP 214.A OD1 no hydrogen 3.178 N/A ASP 155.A N HIS 153.A ND1 no hydrogen 3.221 N/A THR 158.A N GLU 224.A OE2 no hydrogen 2.906 N/A THR 158.A OG1 GLU 224.A OE1 no hydrogen 2.611 N/A ARG 159.A NE ASP 184.A OD2 no hydrogen 3.128 N/A ARG 159.A NH2 TYR 185.A OH no hydrogen 3.131 N/A ASN 160.A N ALA 157.A O no hydrogen 2.966 N/A ASN 160.A ND2 ASP 155.A O no hydrogen 2.555 N/A CYS 161.A N THR 158.A O no hydrogen 3.007 N/A CYS 161.A SG ALA 157.A O no hydrogen 3.680 N/A LEU 162.A N LYS 170.A O no hydrogen 2.793 N/A VAL 163.A N ARG 100.A O no hydrogen 2.766 N/A GLY 164.A N VAL 168.A O no hydrogen 2.652 N/A GLN 165.A NE2 ASP 121.A OD1 no hydrogen 2.954 N/A GLY 166.A N ASP 121.A OD2 no hydrogen 3.068 N/A VAL 169.A N GLN 138.A OE1 no hydrogen 2.973 N/A LYS 170.A N LEU 162.A O no hydrogen 2.942 N/A LYS 170.A NZ GLU 95.A OE1 no hydrogen 2.671 N/A LYS 170.A NZ GLU 95.A OE2 no hydrogen 3.471 N/A ILE 171.A N HIS 76.A O no hydrogen 2.865 N/A GLY 172.A N ASN 160.A O no hydrogen 3.093 N/A GLY 175.A N ASP 173.A OD2 no hydrogen 3.014 N/A SER 177.A OG ASN 160.A OD1 no hydrogen 2.621 N/A ARG 178.A NE MET 193.A O no hydrogen 3.399 N/A ARG 178.A NH1 MET 193.A O no hydrogen 2.992 N/A ASP 179.A N MET 176.A O no hydrogen 3.084 N/A ILE 180.A N MET 176.A O no hydrogen 2.928 N/A TYR 181.A N SER 177.A O no hydrogen 2.815 N/A TYR 181.A OH ASP 101.A OD2 no hydrogen 2.678 N/A ASP 184.A N TYR 181.A O no hydrogen 3.090 N/A TYR 185.A N SER 182.A O no hydrogen 3.124 N/A TYR 185.A OH ASP 155.A OD2 no hydrogen 2.400 N/A TYR 186.A N LEU 194.A O no hydrogen 2.715 N/A VAL 188.A N THR 192.A O no hydrogen 2.902 N/A THR 192.A OG1 GLY 190.A O no hydrogen 3.370 N/A LEU 194.A N TYR 186.A O no hydrogen 3.059 N/A ARG 197.A NH1 PRO 232.A O no hydrogen 3.114 N/A ARG 197.A NH1 TRP 233.A O no hydrogen 2.808 N/A ARG 197.A NH1 LEU 236.A O no hydrogen 3.334 N/A ARG 197.A NH2 LEU 236.A O no hydrogen 3.180 N/A ARG 197.A NH2 ASN 238.A OD1 no hydrogen 3.196 N/A TRP 198.A N PRO 195.A O no hydrogen 3.226 N/A TRP 198.A NE1 GLU 224.A OE2 no hydrogen 2.843 N/A MET 199.A N ILE 196.A O no hydrogen 3.100 N/A GLU 202.A N GLU 202.A OE2 no hydrogen 2.995 N/A SER 203.A N PRO 200.A O no hydrogen 3.101 N/A SER 203.A OG LYS 208.A O no hydrogen 2.425 N/A ILE 204.A N PRO 200.A O no hydrogen 3.143 N/A LEU 205.A N PRO 201.A O no hydrogen 2.846 N/A TYR 206.A N GLU 202.A O no hydrogen 3.142 N/A LYS 208.A N GLU 202.A O no hydrogen 3.106 N/A THR 210.A N SER 213.A OG no hydrogen 2.936 N/A THR 210.A OG1 GLU 212.A OE1 no hydrogen 3.147 N/A THR 210.A OG1 SER 213.A OG no hydrogen 3.205 N/A THR 211.A OG1 GLU 212.A OE1 no hydrogen 3.036 N/A GLU 212.A N GLU 212.A OE1 no hydrogen 2.794 N/A SER 213.A N THR 210.A O no hydrogen 2.866 N/A SER 213.A N THR 210.A OG1 no hydrogen 3.184 N/A SER 213.A OG GLU 202.A OE1 no hydrogen 3.094 N/A SER 213.A OG THR 210.A O no hydrogen 3.524 N/A SER 213.A OG THR 210.A OG1 no hydrogen 3.205 N/A ASP 214.A N THR 210.A O no hydrogen 3.204 N/A VAL 215.A N THR 211.A O no hydrogen 3.166 N/A TRP 216.A N GLU 212.A O no hydrogen 3.278 N/A SER 217.A N SER 213.A O no hydrogen 3.026 N/A SER 217.A OG TRP 198.A O no hydrogen 2.591 N/A SER 217.A OG SER 213.A O no hydrogen 3.384 N/A PHE 218.A N ASP 214.A O no hydrogen 2.813 N/A GLY 219.A N VAL 215.A O no hydrogen 3.121 N/A VAL 220.A N TRP 216.A O no hydrogen 3.413 N/A VAL 221.A N SER 217.A O no hydrogen 2.861 N/A LEU 222.A N PHE 218.A O no hydrogen 2.811 N/A TRP 223.A N GLY 219.A O no hydrogen 3.014 N/A TRP 223.A NE1 GLU 252.A O no hydrogen 2.989 N/A GLU 224.A N VAL 220.A O no hydrogen 2.832 N/A ILE 225.A N VAL 221.A O no hydrogen 2.823 N/A PHE 226.A N LEU 222.A O no hydrogen 3.034 N/A THR 227.A N GLU 224.A O no hydrogen 3.343 N/A THR 227.A OG1 TRP 223.A O no hydrogen 2.940 N/A THR 227.A OG1 GLU 224.A O no hydrogen 3.226 N/A TYR 228.A N ILE 225.A O no hydrogen 3.204 N/A GLY 229.A N GLU 224.A O no hydrogen 2.800 N/A GLN 231.A NE2 THR 183.A O no hydrogen 3.109 N/A GLN 231.A NE2 ASP 184.A OD1 no hydrogen 2.674 N/A LEU 236.A N TRP 233.A O no hydrogen 2.710 N/A SER 237.A N GLU 240.A OE1 no hydrogen 2.549 N/A GLU 240.A N SER 237.A OG no hydrogen 3.026 N/A ALA 241.A N SER 237.A O no hydrogen 2.823 N/A ILE 242.A N ASN 238.A O no hydrogen 3.001 N/A ASP 243.A N THR 239.A O no hydrogen 3.063 N/A CYS 244.A N GLU 240.A O no hydrogen 3.059 N/A CYS 244.A SG GLU 240.A O no hydrogen 3.589 N/A ILE 245.A N ALA 241.A O no hydrogen 3.098 N/A THR 246.A N ILE 242.A O no hydrogen 2.979 N/A THR 246.A OG1 ILE 242.A O no hydrogen 2.622 N/A THR 246.A OG1 ASP 243.A O no hydrogen 2.833 N/A GLN 247.A N ASP 243.A O no hydrogen 2.707 N/A GLY 248.A N ILE 245.A O no hydrogen 3.344 N/A ARG 249.A N CYS 244.A O no hydrogen 3.145 N/A ARG 253.A NH1 CYS 257.A O no hydrogen 2.743 N/A ARG 253.A NH1 TYR 296.A OH no hydrogen 2.470 N/A CYS 257.A N PRO 254.A O no hydrogen 2.947 N/A CYS 257.A SG PRO 258.A O no hydrogen 3.484 N/A TYR 262.A N PRO 258.A O no hydrogen 2.953 N/A TYR 262.A OH LEU 251.A O no hydrogen 2.637 N/A ALA 263.A N PRO 259.A O no hydrogen 2.960 N/A ILE 264.A N GLU 260.A O no hydrogen 3.207 N/A MET 265.A N VAL 261.A O no hydrogen 3.151 N/A ARG 266.A N TYR 262.A O no hydrogen 3.061 N/A GLY 267.A N ALA 263.A O no hydrogen 2.977 N/A CYS 268.A N ILE 264.A O no hydrogen 3.037 N/A CYS 268.A N MET 265.A O no hydrogen 3.046 N/A CYS 268.A SG ILE 264.A O no hydrogen 3.314 N/A TRP 269.A N MET 265.A O no hydrogen 3.033 N/A TRP 269.A N ARG 266.A O no hydrogen 3.153 N/A ARG 271.A NH1 THR 246.A O no hydrogen 2.757 N/A ARG 271.A NH2 THR 246.A O no hydrogen 3.339 N/A GLN 275.A N GLU 272.A O no hydrogen 2.850 N/A ARG 276.A N PRO 273.A O no hydrogen 3.273 N/A ARG 276.A NE GLN 270.A O no hydrogen 2.624 N/A ARG 276.A NH1 GLU 202.A OE1 no hydrogen 2.914 N/A ARG 276.A NH1 GLU 202.A OE2 no hydrogen 3.388 N/A ARG 276.A NH1 GLU 212.A O no hydrogen 2.950 N/A ARG 276.A NH2 GLU 202.A OE2 no hydrogen 2.925 N/A ARG 276.A NH2 GLN 270.A O no hydrogen 3.102 N/A HIS 277.A N GLY 267.A O no hydrogen 3.171 N/A VAL 282.A N SER 278.A O no hydrogen 3.280 N/A HIS 283.A N ILE 279.A O no hydrogen 2.960 N/A ALA 284.A N LYS 280.A O no hydrogen 2.871 N/A ARG 285.A N ASP 281.A O no hydrogen 2.895 N/A LEU 286.A N VAL 282.A O no hydrogen 3.136 N/A GLN 287.A N HIS 283.A O no hydrogen 2.753 N/A ALA 288.A N ALA 284.A O no hydrogen 3.022 N/A LEU 289.A N ARG 285.A O no hydrogen 2.941 N/A ALA 290.A N LEU 286.A O no hydrogen 2.699 N/A GLN 291.A N GLN 287.A O no hydrogen 2.815 N/A ALA 292.A N ALA 288.A O no hydrogen 3.073 N/A TYR 296.A OH ARG 255.A O no hydrogen 2.521 N/A LEU 297.A N VAL 295.A O no hydrogen 2.790 N/A