Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7vkn_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N GLU 66.A OE2 no hydrogen 3.392 N/A HIS 7.A ND1 HIS 8.A O no hydrogen 2.612 N/A HIS 8.A ND1 VAL 6.A O no hydrogen 2.955 N/A ILE 9.A N VAL 82.A O no hydrogen 3.038 N/A ARG 11.A NE GLU 85.A O no hydrogen 3.352 N/A ARG 11.A NH1 GLY 86.A O no hydrogen 2.675 N/A ARG 11.A NH1 PRO 88.A O no hydrogen 2.638 N/A ASP 13.A N LYS 10.A O no hydrogen 2.792 N/A ILE 14.A N ARG 11.A O no hydrogen 2.988 N/A VAL 15.A N GLU 32.A O no hydrogen 2.914 N/A LYS 17.A N LEU 30.A O no hydrogen 2.890 N/A TRP 18.A N LEU 30.A O no hydrogen 3.506 N/A LEU 20.A N VAL 28.A O no hydrogen 2.804 N/A GLY 21.A N VAL 28.A O no hydrogen 3.243 N/A ALA 24.A N ARG 176.A O no hydrogen 2.829 N/A LYS 27.A N ALA 49.A O no hydrogen 3.086 N/A VAL 28.A N GLY 21.A O no hydrogen 3.065 N/A PHE 29.A N VAL 47.A O no hydrogen 2.950 N/A LEU 30.A N TRP 18.A O no hydrogen 2.831 N/A ALA 31.A N VAL 45.A O no hydrogen 2.992 N/A GLU 32.A N VAL 15.A O no hydrogen 2.895 N/A CYS 33.A N MET 43.A O no hydrogen 2.724 N/A CYS 33.A SG ASP 13.A O no hydrogen 3.416 N/A HIS 34.A N ASP 13.A O no hydrogen 3.029 N/A ASN 35.A N ASP 41.A O no hydrogen 2.757 N/A ASN 35.A ND2 ASP 41.A OD2 no hydrogen 3.119 N/A GLN 40.A NE2 LYS 42.A O no hydrogen 3.401 N/A MET 43.A N CYS 33.A O no hydrogen 3.074 N/A VAL 45.A N ALA 31.A O no hydrogen 2.747 N/A ALA 46.A N PHE 93.A O no hydrogen 2.932 N/A VAL 47.A N PHE 29.A O no hydrogen 3.029 N/A LYS 48.A N MET 91.A O no hydrogen 2.687 N/A ALA 49.A N LYS 27.A O no hydrogen 2.845 N/A LEU 50.A N LEU 89.A O no hydrogen 3.027 N/A LYS 51.A N PHE 25.A O no hydrogen 2.672 N/A SER 54.A OG SER 56.A OG no hydrogen 2.641 N/A SER 56.A OG SER 54.A OG no hydrogen 2.641 N/A ARG 58.A N SER 54.A O no hydrogen 3.035 N/A GLN 59.A N GLU 55.A O no hydrogen 3.260 N/A ASP 60.A N SER 56.A O no hydrogen 3.238 N/A PHE 61.A N ALA 57.A O no hydrogen 2.678 N/A GLN 62.A N ARG 58.A O no hydrogen 3.232 N/A GLN 62.A N GLN 59.A O no hydrogen 3.124 N/A ARG 63.A N GLN 59.A O no hydrogen 3.187 N/A GLU 64.A N ASP 60.A O no hydrogen 2.809 N/A ALA 65.A N PHE 61.A O no hydrogen 2.820 N/A GLU 66.A N GLN 62.A O no hydrogen 2.623 N/A LEU 67.A N ARG 63.A O no hydrogen 2.677 N/A LEU 68.A N GLU 64.A O no hydrogen 2.748 N/A THR 69.A N ALA 65.A O no hydrogen 3.006 N/A THR 69.A OG1 ALA 65.A O no hydrogen 2.503 N/A MET 70.A N GLU 66.A O no hydrogen 3.057 N/A LEU 71.A N LEU 67.A O no hydrogen 3.046 N/A GLN 72.A N TYR 144.A OH no hydrogen 3.274 N/A GLN 72.A NE2 LEU 71.A O no hydrogen 2.662 N/A ILE 76.A N HIS 73.A O no hydrogen 3.110 N/A VAL 77.A N ILE 170.A O no hydrogen 2.916 N/A ARG 78.A N GLU 94.A OE1 no hydrogen 2.650 N/A PHE 80.A N VAL 92.A O no hydrogen 2.789 N/A VAL 82.A N HIS 7.A O no hydrogen 3.125 N/A CYS 83.A N LEU 90.A O no hydrogen 3.030 N/A LEU 90.A N CYS 83.A O no hydrogen 3.255 N/A MET 91.A N LYS 48.A O no hydrogen 2.910 N/A VAL 92.A N GLY 81.A O no hydrogen 2.997 N/A PHE 93.A N ALA 46.A O no hydrogen 2.678 N/A GLU 94.A N ARG 78.A O no hydrogen 3.069 N/A ARG 97.A NH2 GLU 119.A OE1 no hydrogen 3.241 N/A HIS 98.A N VAL 162.A O no hydrogen 2.926 N/A HIS 98.A NE2 ASP 120.A OD1 no hydrogen 2.820 N/A HIS 98.A NE2 ASP 120.A OD2 no hydrogen 2.827 N/A ARG 99.A N.A MET 96.A O no hydrogen 3.205 N/A ARG 99.A N.B MET 96.A O no hydrogen 3.175 N/A ARG 99.A NH1.A ARG 97.A O no hydrogen 2.459 N/A ARG 99.A NH1.B LEU 20.A O no hydrogen 2.662 N/A LEU 101.A N CYS 160.A O no hydrogen 2.850 N/A ASN 102.A N ASP 100.A OD1 no hydrogen 2.813 N/A ASN 102.A ND2 THR 157.A OG1 no hydrogen 2.904 N/A ASN 102.A ND2 GLU 222.A OE1 no hydrogen 3.502 N/A ASN 102.A ND2 GLY 227.A O no hydrogen 3.303 N/A ARG 103.A N ASP 100.A OD1 no hydrogen 3.053 N/A ARG 103.A NH1 HIS 98.A O no hydrogen 2.550 N/A PHE 104.A N ASP 100.A O no hydrogen 3.181 N/A LEU 105.A N LEU 101.A O no hydrogen 2.849 N/A ARG 106.A N ASN 102.A O no hydrogen 3.046 N/A ARG 106.A NE ASN 102.A OD1 no hydrogen 3.064 N/A SER 107.A N ARG 103.A O no hydrogen 2.839 N/A SER 107.A N PHE 104.A O no hydrogen 3.157 N/A SER 107.A OG ARG 103.A O no hydrogen 3.317 N/A SER 107.A OG PHE 104.A O no hydrogen 2.619 N/A HIS 108.A N LEU 105.A O no hydrogen 3.115 N/A HIS 108.A ND1 GLY 124.A O no hydrogen 3.180 N/A GLY 109.A N ARG 106.A O no hydrogen 3.373 N/A ALA 112.A N GLY 109.A O no hydrogen 3.229 N/A LEU 126.A N TYR 226.A OH no hydrogen 3.047 N/A GLY 127.A N GLN 130.A OE1 no hydrogen 2.527 N/A LEU 131.A N GLY 127.A O no hydrogen 2.893 N/A LEU 132.A N LEU 128.A O no hydrogen 2.829 N/A ALA 133.A N GLY 129.A O no hydrogen 2.890 N/A VAL 134.A N GLN 130.A O no hydrogen 2.860 N/A ALA 135.A N LEU 131.A O no hydrogen 2.972 N/A SER 136.A N LEU 132.A O no hydrogen 2.787 N/A GLN 137.A N ALA 133.A O no hydrogen 3.014 N/A GLN 137.A NE2 ALA 133.A O no hydrogen 3.474 N/A GLN 137.A NE2 LEU 166.A O no hydrogen 2.934 N/A VAL 138.A N VAL 134.A O no hydrogen 3.141 N/A ALA 139.A N ALA 135.A O no hydrogen 3.196 N/A ALA 140.A N SER 136.A O no hydrogen 2.909 N/A GLY 141.A N GLN 137.A O no hydrogen 3.208 N/A MET 142.A N VAL 138.A O no hydrogen 3.035 N/A VAL 143.A N ALA 139.A O no hydrogen 2.733 N/A TYR 144.A N ALA 140.A O no hydrogen 3.276 N/A LEU 145.A N GLY 141.A O no hydrogen 3.173 N/A ALA 146.A N MET 142.A O no hydrogen 2.822 N/A GLY 147.A N VAL 143.A O no hydrogen 2.958 N/A LEU 148.A N TYR 144.A O no hydrogen 3.207 N/A LEU 148.A N LEU 145.A O no hydrogen 3.215 N/A HIS 149.A N ALA 146.A O no hydrogen 2.592 N/A PHE 150.A N LEU 145.A O no hydrogen 2.732 N/A HIS 152.A N ASP 212.A OD2 no hydrogen 2.704 N/A HIS 152.A NE2 ASP 172.A O no hydrogen 2.849 N/A ASP 154.A N HIS 152.A ND1 no hydrogen 3.071 N/A THR 157.A N GLU 222.A OE2 no hydrogen 2.995 N/A THR 157.A OG1 GLU 222.A OE1 no hydrogen 2.765 N/A ARG 158.A NE TYR 183.A OH no hydrogen 3.115 N/A ARG 158.A NH2 TYR 183.A OH no hydrogen 3.227 N/A ASN 159.A N ALA 156.A O no hydrogen 2.809 N/A ASN 159.A ND2 ASP 154.A O no hydrogen 2.525 N/A ASN 159.A ND2 ASP 154.A OD2 no hydrogen 2.989 N/A CYS 160.A N THR 157.A O no hydrogen 3.129 N/A CYS 160.A SG ALA 156.A O no hydrogen 3.776 N/A LEU 161.A N LYS 169.A O no hydrogen 2.805 N/A VAL 162.A N ARG 99.A O.A no hydrogen 2.773 N/A VAL 162.A N ARG 99.A O.B no hydrogen 2.764 N/A GLY 163.A N VAL 167.A O no hydrogen 2.775 N/A GLY 165.A N ASP 120.A OD2 no hydrogen 2.807 N/A VAL 167.A N GLY 163.A O no hydrogen 3.153 N/A VAL 168.A N GLN 137.A OE1 no hydrogen 2.926 N/A LYS 169.A N LEU 161.A O no hydrogen 2.995 N/A LYS 169.A NZ GLU 94.A OE1 no hydrogen 1.813 N/A ILE 170.A N HIS 75.A O no hydrogen 2.998 N/A GLY 171.A N ASN 159.A O no hydrogen 2.768 N/A ASP 172.A N ASN 159.A O no hydrogen 3.134 N/A GLY 174.A N ASP 172.A OD2 no hydrogen 2.748 N/A SER 180.A OG ASP 182.A OD2 no hydrogen 2.669 N/A TYR 183.A OH ASP 154.A OD2 no hydrogen 2.284 N/A TYR 184.A N LEU 192.A O no hydrogen 2.847 N/A VAL 186.A N THR 190.A O no hydrogen 3.078 N/A THR 190.A N GLY 187.A O no hydrogen 3.089 N/A THR 190.A OG1 GLY 188.A O no hydrogen 3.551 N/A LEU 192.A N TYR 184.A O no hydrogen 3.110 N/A ARG 195.A NH1 PRO 230.A O no hydrogen 2.877 N/A ARG 195.A NH1 TRP 231.A O no hydrogen 2.580 N/A ARG 195.A NH2 LEU 234.A O no hydrogen 3.152 N/A TRP 196.A N PRO 193.A O no hydrogen 3.060 N/A TRP 196.A NE1 GLU 222.A OE2 no hydrogen 2.884 N/A MET 197.A N ILE 194.A O no hydrogen 3.040 N/A SER 201.A N PRO 198.A O no hydrogen 3.164 N/A SER 201.A OG LYS 206.A O no hydrogen 2.822 N/A ILE 202.A N PRO 198.A O no hydrogen 3.269 N/A LEU 203.A N PRO 199.A O no hydrogen 2.728 N/A TYR 204.A N GLU 200.A O no hydrogen 3.147 N/A ARG 205.A NE SER 201.A O no hydrogen 3.431 N/A ARG 205.A NH1 ILE 202.A O no hydrogen 2.947 N/A LYS 206.A N GLU 200.A O no hydrogen 3.218 N/A THR 208.A N SER 211.A OG no hydrogen 2.600 N/A THR 208.A OG1 GLU 210.A OE2 no hydrogen 2.913 N/A THR 208.A OG1 SER 211.A OG no hydrogen 3.251 N/A THR 209.A OG1 GLU 210.A OE2 no hydrogen 2.956 N/A GLU 210.A N THR 208.A OG1 no hydrogen 2.932 N/A GLU 210.A N GLU 210.A OE2 no hydrogen 2.675 N/A SER 211.A N THR 208.A OG1 no hydrogen 3.334 N/A SER 211.A OG GLU 200.A OE2 no hydrogen 2.916 N/A SER 211.A OG THR 208.A O no hydrogen 3.060 N/A SER 211.A OG THR 208.A OG1 no hydrogen 3.251 N/A ASP 212.A N THR 208.A O no hydrogen 3.191 N/A VAL 213.A N THR 209.A O no hydrogen 3.108 N/A TRP 214.A N GLU 210.A O no hydrogen 3.169 N/A SER 215.A N SER 211.A O no hydrogen 3.072 N/A SER 215.A OG ASP 212.A O no hydrogen 3.236 N/A PHE 216.A N ASP 212.A O no hydrogen 2.806 N/A GLY 217.A N VAL 213.A O no hydrogen 3.173 N/A VAL 218.A N SER 215.A O no hydrogen 2.892 N/A VAL 219.A N SER 215.A O no hydrogen 3.104 N/A VAL 219.A N PHE 216.A O no hydrogen 2.863 N/A LEU 220.A N PHE 216.A O no hydrogen 2.963 N/A TRP 221.A N GLY 217.A O no hydrogen 3.193 N/A TRP 221.A NE1 GLU 250.A O no hydrogen 3.095 N/A GLU 222.A N VAL 218.A O no hydrogen 2.842 N/A ILE 223.A N VAL 219.A O no hydrogen 2.738 N/A PHE 224.A N LEU 220.A O no hydrogen 2.860 N/A THR 225.A N GLU 222.A O no hydrogen 3.290 N/A THR 225.A OG1 TRP 221.A O no hydrogen 2.881 N/A THR 225.A OG1 GLU 222.A O no hydrogen 3.091 N/A TYR 226.A N ILE 223.A O no hydrogen 3.001 N/A GLY 227.A N GLU 222.A O no hydrogen 2.653 N/A LYS 228.A N THR 225.A OG1 no hydrogen 3.288 N/A GLN 229.A NE2 ASP 182.A OD1 no hydrogen 3.211 N/A LEU 234.A N TRP 231.A O no hydrogen 2.760 N/A SER 235.A N GLU 238.A OE1 no hydrogen 2.837 N/A SER 235.A OG GLU 238.A OE1 no hydrogen 2.693 N/A GLU 238.A N SER 235.A OG no hydrogen 3.049 N/A ALA 239.A N SER 235.A O no hydrogen 2.778 N/A ILE 240.A N ASN 236.A O no hydrogen 3.039 N/A ASP 241.A N THR 237.A O no hydrogen 3.214 N/A CYS 242.A N GLU 238.A O no hydrogen 3.037 N/A CYS 242.A SG GLU 238.A O no hydrogen 3.469 N/A ILE 243.A N ALA 239.A O no hydrogen 2.803 N/A THR 244.A N ILE 240.A O no hydrogen 2.980 N/A THR 244.A OG1 ILE 240.A O no hydrogen 2.503 N/A THR 244.A OG1 ASP 241.A O no hydrogen 2.930 N/A GLN 245.A N ASP 241.A O no hydrogen 2.852 N/A GLN 245.A N CYS 242.A O no hydrogen 3.191 N/A GLY 246.A N ILE 243.A O no hydrogen 3.416 N/A ARG 247.A N CYS 242.A O no hydrogen 2.956 N/A ARG 251.A NH1 CYS 255.A O no hydrogen 2.986 N/A CYS 255.A N PRO 252.A O no hydrogen 2.873 N/A CYS 255.A SG PRO 256.A O no hydrogen 3.200 N/A GLU 258.A N GLU 258.A OE1 no hydrogen 2.988 N/A VAL 259.A N PRO 256.A O no hydrogen 3.060 N/A TYR 260.A N PRO 256.A O no hydrogen 3.141 N/A TYR 260.A OH LEU 249.A O no hydrogen 2.254 N/A ALA 261.A N PRO 257.A O no hydrogen 2.840 N/A MET 263.A N VAL 259.A O no hydrogen 3.087 N/A ARG 264.A N TYR 260.A O no hydrogen 2.900 N/A GLY 265.A N ALA 261.A O no hydrogen 3.021 N/A CYS 266.A N ILE 262.A O no hydrogen 3.141 N/A CYS 266.A N MET 263.A O no hydrogen 2.627 N/A CYS 266.A SG VAL 213.A O no hydrogen 3.485 N/A CYS 266.A SG ILE 262.A O no hydrogen 3.489 N/A TRP 267.A N MET 263.A O no hydrogen 3.202 N/A GLN 273.A N GLU 270.A O no hydrogen 2.945 N/A ARG 274.A N PRO 271.A O no hydrogen 2.930 N/A ARG 274.A NE GLN 268.A O no hydrogen 2.708 N/A ARG 274.A NH1 GLU 200.A OE1 no hydrogen 2.546 N/A ARG 274.A NH1 GLU 210.A O no hydrogen 2.929 N/A ARG 274.A NH2 GLU 200.A OE1 no hydrogen 3.057 N/A ARG 274.A NH2 GLN 268.A O no hydrogen 2.889 N/A ASP 279.A N SER 276.A OG no hydrogen 3.271 N/A VAL 280.A N SER 276.A O no hydrogen 3.130 N/A HIS 281.A N ILE 277.A O no hydrogen 2.945 N/A ALA 282.A N LYS 278.A O no hydrogen 3.089 N/A ARG 283.A N ASP 279.A O no hydrogen 3.245 N/A ARG 283.A NH2 HIS 275.A NE2 no hydrogen 3.397 N/A LEU 284.A N VAL 280.A O no hydrogen 3.117 N/A GLN 285.A N HIS 281.A O no hydrogen 2.617 N/A ALA 286.A N ALA 282.A O no hydrogen 2.908 N/A LEU 287.A N ARG 283.A O no hydrogen 3.180 N/A ALA 288.A N LEU 284.A O no hydrogen 2.883 N/A GLN 289.A N GLN 285.A O no hydrogen 3.031 N/A GLN 289.A N ALA 286.A O no hydrogen 3.010 N/A ALA 290.A N ALA 286.A O no hydrogen 3.125 N/A TYR 294.A OH ARG 253.A O no hydrogen 2.783 N/A