Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7w3h_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 1.A N ASP 1.A OD1 no hydrogen 2.521 N/A ARG 5.A N ASP 1.A O no hydrogen 3.482 N/A TYR 6.A N LEU 2.A O no hydrogen 2.955 N/A LYS 7.A N TYR 3.A O no hydrogen 2.970 N/A LYS 7.A NZ TYR 3.A OH no hydrogen 2.832 N/A LYS 8.A N SER 4.A O no hydrogen 2.905 N/A LEU 9.A N ARG 5.A O no hydrogen 2.935 N/A GLN 10.A N TYR 6.A O no hydrogen 3.015 N/A GLN 11.A N LYS 7.A O no hydrogen 2.961 N/A GLU 12.A N LYS 8.A O no hydrogen 2.918 N/A LEU 13.A N LEU 9.A O no hydrogen 2.983 N/A GLU 14.A N GLN 10.A O no hydrogen 3.012 N/A PHE 15.A N GLN 11.A O no hydrogen 2.923 N/A LEU 16.A N GLU 12.A O no hydrogen 2.943 N/A GLU 17.A N LEU 13.A O no hydrogen 3.073 N/A GLN 19.A N PHE 15.A O no hydrogen 3.026 N/A GLU 20.A N LEU 16.A O no hydrogen 2.962 N/A GLU 21.A N GLU 17.A O no hydrogen 2.996 N/A TYR 22.A N VAL 18.A O no hydrogen 3.004 N/A ILE 23.A N GLN 19.A O no hydrogen 3.023 N/A LYS 24.A N GLU 20.A O no hydrogen 2.996 N/A ASP 25.A N GLU 21.A O no hydrogen 3.050 N/A GLU 26.A N TYR 22.A O no hydrogen 2.949 N/A GLN 27.A N ILE 23.A O no hydrogen 2.963 N/A LYS 28.A N LYS 24.A O no hydrogen 3.046 N/A LYS 28.A NZ ASP 25.A OD1 no hydrogen 3.106 N/A ASN 29.A N ASP 25.A O no hydrogen 3.023 N/A LEU 30.A N GLU 26.A O no hydrogen 2.921 N/A LYS 31.A N GLN 27.A O no hydrogen 2.984 N/A LYS 32.A N LYS 28.A O no hydrogen 3.068 N/A GLU 33.A N ASN 29.A O no hydrogen 2.973 N/A PHE 34.A N LEU 30.A O no hydrogen 2.905 N/A LEU 35.A N LYS 31.A O no hydrogen 3.031 N/A HIS 36.A N LYS 32.A O no hydrogen 3.040 N/A ALA 37.A N GLU 33.A O no hydrogen 2.935 N/A GLN 38.A N PHE 34.A O no hydrogen 2.937 N/A GLU 39.A N LEU 35.A O no hydrogen 3.004 N/A GLU 40.A N HIS 36.A O no hydrogen 2.940 N/A VAL 41.A N ALA 37.A O no hydrogen 2.943 N/A LYS 42.A N GLN 38.A O no hydrogen 2.962 N/A ARG 43.A N GLU 39.A O no hydrogen 2.936 N/A ILE 44.A N VAL 41.A O no hydrogen 3.422 N/A GLN 45.A N LYS 42.A O no hydrogen 3.363 N/A SER 46.A OG ARG 43.A O no hydrogen 3.418 N/A VAL 50.A N LEU 94.A O no hydrogen 2.949 N/A GLY 52.A N VAL 92.A O no hydrogen 2.421 N/A GLN 53.A N GLY 66.A O no hydrogen 2.666 N/A PHE 54.A N ALA 90.A O no hydrogen 2.955 N/A LEU 55.A N ILE 64.A O no hydrogen 3.068 N/A GLU 56.A N ILE 64.A O no hydrogen 3.114 N/A GLN 60.A N GLN 60.A OE1 no hydrogen 2.767 N/A THR 62.A OG1 ASP 59.A OD1 no hydrogen 2.390 N/A THR 62.A OG1 GLN 60.A O no hydrogen 3.291 N/A ALA 63.A N VAL 75.A O no hydrogen 2.964 N/A ILE 64.A N GLU 56.A O no hydrogen 2.817 N/A VAL 65.A N TYR 73.A O no hydrogen 3.395 N/A GLY 66.A N GLN 53.A O no hydrogen 2.634 N/A SER 67.A OG THR 69.A OG1 no hydrogen 2.994 N/A SER 67.A OG GLY 70.A O no hydrogen 2.342 N/A THR 69.A OG1 SER 67.A OG no hydrogen 2.994 N/A THR 69.A OG1 GLY 70.A O no hydrogen 3.219 N/A GLY 70.A N SER 67.A O no hydrogen 3.168 N/A SER 71.A OG GLY 70.A O no hydrogen 2.620 N/A SER 71.A OG SER 71.A O no hydrogen 2.506 N/A SER 71.A OG TYR 73.A OH no hydrogen 3.027 N/A TYR 73.A N VAL 65.A O no hydrogen 2.907 N/A VAL 75.A N ALA 63.A O no hydrogen 3.100 N/A ILE 77.A N ASN 61.A O no hydrogen 2.696 N/A LEU 78.A N LEU 101.A O no hydrogen 3.390 N/A ILE 81.A N LEU 78.A O no hydrogen 3.401 N/A ARG 83.A NE ILE 81.A O no hydrogen 2.936 N/A ARG 83.A NH2 SER 79.A O no hydrogen 3.373 N/A GLU 84.A N ASP 82.A OD1 no hydrogen 2.850 N/A VAL 92.A N GLY 52.A O no hydrogen 2.796 N/A ALA 93.A N ASP 103.A O no hydrogen 3.042 N/A LEU 94.A N VAL 50.A O no hydrogen 2.635 N/A HIS 95.A N ALA 100.A O no hydrogen 3.050 N/A SER 98.A N HIS 95.A ND1 no hydrogen 3.351 N/A LEU 101.A N ARG 76.A O no hydrogen 3.045 N/A VAL 102.A N ALA 93.A O no hydrogen 3.241 N/A LEU 105.A N SER 91.A O no hydrogen 3.005 N/A GLU 108.A N GLU 108.A OE1 no hydrogen 2.757 N/A THR 117.A N MET 115.A O no hydrogen 2.733 N/A SER 118.A N THR 117.A OG1 no hydrogen 2.571 N/A VAL 124.A N HIS 183.A ND1 no hydrogen 3.256 N/A MET 125.A N ASP 128.A OD2 no hydrogen 3.193 N/A ASP 133.A N GLY 131.A O no hydrogen 2.849 N/A ILE 134.A N ASP 133.A OD1 no hydrogen 2.726 N/A GLN 135.A N GLN 135.A OE1 no hydrogen 2.776 N/A GLN 135.A NE2 GLU 294.A O no hydrogen 3.164 N/A LYS 136.A N MET 132.A O no hydrogen 2.880 N/A GLN 137.A N ASP 133.A O no hydrogen 2.965 N/A GLN 137.A N ILE 134.A O no hydrogen 2.575 N/A GLU 138.A N ILE 134.A O no hydrogen 3.020 N/A GLU 138.A N GLU 138.A OE1 no hydrogen 3.124 N/A VAL 139.A N GLN 135.A O no hydrogen 2.963 N/A ARG 140.A N LYS 136.A O no hydrogen 2.913 N/A GLU 141.A N GLN 137.A O no hydrogen 2.894 N/A ALA 142.A N GLU 138.A O no hydrogen 2.960 N/A GLU 144.A N ARG 140.A O no hydrogen 2.812 N/A LEU 145.A N ARG 140.A O no hydrogen 3.000 N/A LEU 147.A N GLU 144.A O no hydrogen 3.191 N/A THR 148.A N GLU 144.A O no hydrogen 3.318 N/A THR 148.A OG1 GLU 144.A O no hydrogen 3.218 N/A THR 148.A OG1 HIS 149.A ND1 no hydrogen 3.011 N/A HIS 149.A N LEU 145.A O no hydrogen 2.809 N/A LYS 154.A N PHE 150.A O no hydrogen 2.937 N/A GLN 155.A N GLU 151.A O no hydrogen 2.713 N/A GLY 157.A N TYR 153.A O no hydrogen 3.096 N/A ILE 158.A N TYR 153.A O no hydrogen 3.356 N/A ARG 162.A NE ASN 264.A O no hydrogen 2.742 N/A ARG 162.A NH1 PRO 160.A O no hydrogen 3.478 N/A ARG 162.A NH2 ASN 264.A O no hydrogen 2.921 N/A VAL 164.A N VAL 269.A O no hydrogen 3.382 N/A LEU 165.A N ARG 291.A O no hydrogen 2.772 N/A MET 166.A N MET 271.A O no hydrogen 3.107 N/A TYR 167.A N ILE 293.A O no hydrogen 2.974 N/A TYR 167.A OH GLU 294.A OE1 no hydrogen 2.614 N/A GLY 168.A N THR 273.A O no hydrogen 3.222 N/A CYS 172.A SG PRO 169.A O no hydrogen 3.380 N/A CYS 172.A SG PHE 295.A O no hydrogen 3.294 N/A LYS 174.A NZ PRO 169.A O no hydrogen 2.820 N/A LYS 179.A N THR 175.A O no hydrogen 2.955 N/A LYS 179.A NZ THR 175.A O no hydrogen 2.962 N/A ALA 180.A N MET 176.A O no hydrogen 2.836 N/A VAL 181.A N LEU 177.A O no hydrogen 2.919 N/A ALA 182.A N ALA 178.A O no hydrogen 2.900 N/A HIS 183.A N LYS 179.A O no hydrogen 2.903 N/A HIS 184.A N ALA 180.A O no hydrogen 2.955 N/A THR 185.A OG1 GLU 144.A OE2 no hydrogen 2.295 N/A THR 185.A OG1 VAL 181.A O no hydrogen 2.477 N/A ALA 188.A N PRO 221.A O no hydrogen 3.156 N/A ILE 190.A N ILE 223.A O no hydrogen 2.978 N/A VAL 192.A N PHE 225.A O no hydrogen 3.191 N/A SER 195.A OG GLU 196.A OE1 no hydrogen 3.051 N/A GLU 196.A N VAL 193.A O no hydrogen 3.433 N/A GLN 199.A NE2 GLU 196.A O no hydrogen 2.654 N/A GLN 199.A NE2 VAL 198.A O no hydrogen 3.607 N/A GLY 203.A N GLU 246.A OE2 no hydrogen 2.569 N/A ARG 207.A NE GLU 204.A OE1 no hydrogen 3.339 N/A ARG 207.A NH2 GLU 204.A OE1 no hydrogen 3.293 N/A MET 208.A N GLU 204.A O no hydrogen 2.904 N/A VAL 209.A N GLY 205.A O no hydrogen 2.971 N/A ARG 210.A N PRO 206.A O no hydrogen 2.949 N/A ARG 210.A NE GLU 253.A OE2 no hydrogen 2.395 N/A ASP 211.A N ARG 207.A O no hydrogen 2.908 N/A VAL 212.A N MET 208.A O no hydrogen 2.876 N/A PHE 213.A N VAL 209.A O no hydrogen 3.027 N/A ARG 214.A N ARG 210.A O no hydrogen 2.901 N/A LEU 215.A N ASP 211.A O no hydrogen 2.879 N/A ALA 216.A N VAL 212.A O no hydrogen 2.933 N/A LYS 217.A N PHE 213.A O no hydrogen 2.912 N/A GLU 218.A N ARG 214.A O no hydrogen 2.888 N/A ASN 219.A N LEU 215.A O no hydrogen 3.338 N/A ALA 222.A N ASN 266.A O no hydrogen 3.164 N/A ILE 223.A N ALA 188.A O no hydrogen 2.766 N/A ILE 224.A N LYS 268.A O no hydrogen 2.730 N/A PHE 225.A N ILE 190.A O no hydrogen 2.991 N/A ILE 226.A N ILE 270.A O no hydrogen 3.076 N/A ASP 227.A N VAL 192.A O no hydrogen 2.884 N/A THR 234.A OG1 THR 278.A O no hydrogen 3.012 N/A LYS 235.A N THR 234.A OG1 no hydrogen 2.512 N/A ARG 236.A NE ASP 280.A OD2 no hydrogen 2.928 N/A THR 241.A OG1 GLY 242.A O no hydrogen 2.964 N/A THR 241.A OG1 ASP 244.A OD2 no hydrogen 3.447 N/A ARG 249.A N ARG 245.A O no hydrogen 2.890 N/A ARG 249.A NH1 GLU 246.A OE1 no hydrogen 3.185 N/A ILE 250.A N GLU 246.A O no hydrogen 2.986 N/A LEU 251.A N VAL 247.A O no hydrogen 3.431 N/A LEU 252.A N GLN 248.A O no hydrogen 2.877 N/A GLU 253.A N ARG 249.A O no hydrogen 2.922 N/A LEU 254.A N ILE 250.A O no hydrogen 2.949 N/A LEU 255.A N LEU 251.A O no hydrogen 2.896 N/A ASN 256.A N LEU 252.A O no hydrogen 2.897 N/A GLN 257.A N GLU 253.A O no hydrogen 2.908 N/A MET 258.A N LEU 254.A O no hydrogen 2.922 N/A ASP 259.A N LEU 255.A O no hydrogen 2.905 N/A ASN 264.A ND2 MET 258.A O no hydrogen 3.311 N/A LYS 268.A N ALA 222.A O no hydrogen 3.102 N/A VAL 269.A N ARG 162.A O no hydrogen 3.274 N/A ILE 270.A N ILE 224.A O no hydrogen 2.866 N/A MET 271.A N VAL 164.A O no hydrogen 3.008 N/A THR 273.A N MET 166.A O no hydrogen 3.096 N/A THR 273.A OG1 ASP 230.A OD1 no hydrogen 2.356 N/A THR 273.A OG1 ASN 274.A O no hydrogen 3.548 N/A ASN 274.A N ASP 230.A OD1 no hydrogen 3.233 N/A LEU 279.A N ALA 276.A O no hydrogen 3.271 N/A ALA 282.A N ASP 280.A OD1 no hydrogen 2.925 N/A LEU 283.A N ASP 280.A O no hydrogen 2.885 N/A LEU 284.A N ASP 280.A O no hydrogen 3.370 N/A ARG 285.A NH1 PRO 286.A O no hydrogen 2.683 N/A ARG 285.A NH2 ASP 259.A OD2 no hydrogen 2.753 N/A GLY 287.A N ASP 290.A OD1 no hydrogen 2.418 N/A ARG 288.A NH2 LEU 255.A O no hydrogen 2.775 N/A LEU 289.A N ARG 285.A O no hydrogen 3.507 N/A ARG 291.A N GLY 163.A O no hydrogen 3.133 N/A LYS 292.A NZ LEU 284.A O no hydrogen 3.142 N/A LYS 292.A NZ LEU 289.A O no hydrogen 2.726 N/A ILE 293.A N LEU 165.A O no hydrogen 2.756 N/A PHE 295.A N TYR 167.A O no hydrogen 3.082 N/A ILE 306.A N GLN 302.A O no hydrogen 2.792 N/A PHE 307.A N LYS 303.A O no hydrogen 2.907 N/A SER 308.A N ARG 304.A O no hydrogen 2.912 N/A SER 308.A OG ARG 304.A O no hydrogen 3.266 N/A SER 308.A OG LEU 305.A O no hydrogen 2.571 N/A THR 309.A N LEU 305.A O no hydrogen 2.924 N/A THR 309.A OG1 LEU 305.A O no hydrogen 3.043 N/A THR 309.A OG1 ILE 306.A O no hydrogen 2.980 N/A ILE 310.A N ILE 306.A O no hydrogen 2.929 N/A THR 311.A N PHE 307.A O no hydrogen 2.888 N/A THR 311.A OG1 PHE 307.A O no hydrogen 2.452 N/A SER 312.A OG THR 309.A O no hydrogen 3.492 N/A LEU 316.A N MET 314.A O no hydrogen 2.952 N/A SER 317.A OG SER 317.A O no hydrogen 2.521 N/A GLU 319.A N GLU 319.A OE1 no hydrogen 2.749 N/A LEU 322.A N GLU 323.A OE1 no hydrogen 3.358 N/A GLU 323.A N GLU 323.A OE1 no hydrogen 2.670 N/A TYR 325.A N LEU 322.A O no hydrogen 2.971 N/A TYR 325.A N ASP 324.A OD1 no hydrogen 2.879 N/A TYR 325.A OH GLU 362.A OE1 no hydrogen 3.276 N/A VAL 326.A N LEU 322.A O no hydrogen 3.045 N/A ALA 327.A N GLU 323.A O no hydrogen 3.088 N/A ARG 328.A N TYR 325.A O no hydrogen 3.251 N/A ARG 328.A NH2 GLU 362.A OE2 no hydrogen 3.160 N/A SER 333.A N ASP 336.A OD2 no hydrogen 2.879 N/A SER 333.A OG GLY 171.A O no hydrogen 3.356 N/A GLY 334.A N GLY 171.A O no hydrogen 3.297 N/A ILE 337.A N SER 333.A O no hydrogen 3.281 N/A ASN 338.A N GLY 334.A O no hydrogen 2.968 N/A SER 339.A N ALA 335.A O no hydrogen 2.887 N/A SER 339.A OG ALA 335.A O no hydrogen 2.862 N/A ILE 340.A N ASP 336.A O no hydrogen 2.868 N/A CYS 341.A N ILE 337.A O no hydrogen 2.977 N/A CYS 341.A SG ILE 337.A O no hydrogen 3.401 N/A GLN 342.A N ASN 338.A O no hydrogen 2.947 N/A GLU 343.A N SER 339.A O no hydrogen 2.871 N/A SER 344.A N ILE 340.A O no hydrogen 2.911 N/A SER 344.A OG ILE 340.A O no hydrogen 3.055 N/A GLY 345.A N CYS 341.A O no hydrogen 2.955 N/A MET 346.A N GLN 342.A O no hydrogen 2.922 N/A LEU 347.A N GLU 343.A O no hydrogen 2.871 N/A ALA 348.A N SER 344.A O no hydrogen 2.925 N/A VAL 349.A N GLY 345.A O no hydrogen 2.921 N/A ARG 350.A N MET 346.A O no hydrogen 3.154 N/A ARG 350.A NH1 MET 346.A O no hydrogen 3.327 N/A ASN 352.A N VAL 349.A O no hydrogen 3.092 N/A ALA 364.A N ASP 360.A O no hydrogen 2.894 N/A TYR 365.A N PHE 361.A O no hydrogen 2.845 N/A LYS 366.A N GLU 362.A O no hydrogen 2.907 N/A THR 367.A N LYS 363.A O no hydrogen 2.922 N/A THR 367.A OG1 GLU 343.A OE2 no hydrogen 2.629 N/A THR 367.A OG1 LYS 363.A O no hydrogen 2.932 N/A THR 367.A OG1 ALA 364.A O no hydrogen 2.672 N/A VAL 368.A N ALA 364.A O no hydrogen 2.930 N/A ILE 369.A N TYR 365.A O no hydrogen 2.927 N/A HIS 376.A N GLN 374.A O no hydrogen 2.730 N/A GLU 377.A N GLU 377.A OE1 no hydrogen 2.748 N/A PHE 378.A N HIS 376.A O no hydrogen 2.499 N/A TYR 379.A N HIS 376.A O no hydrogen 3.214 N/A