Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7w3h_E.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A NE ASP 3.A O no hydrogen 3.163 N/A ARG 5.A NH2 ASP 3.A O no hydrogen 2.625 N/A ASP 6.A N ASP 3.A OD1 no hydrogen 3.194 N/A LYS 7.A N ASP 3.A OD1 no hydrogen 2.858 N/A LYS 7.A NZ LYS 7.A O no hydrogen 3.368 N/A ALA 8.A N ASP 3.A OD2 no hydrogen 2.386 N/A GLN 10.A N ASP 6.A O no hydrogen 3.012 N/A ASP 11.A N LYS 7.A O no hydrogen 2.900 N/A TYR 12.A N ALA 8.A O no hydrogen 2.861 N/A ARG 13.A N LEU 9.A O no hydrogen 2.906 N/A LYS 14.A N GLN 10.A O no hydrogen 2.892 N/A LYS 15.A N ASP 11.A O no hydrogen 2.909 N/A LEU 16.A N TYR 12.A O no hydrogen 2.861 N/A LEU 17.A N ARG 13.A O no hydrogen 2.896 N/A GLU 18.A N LYS 14.A O no hydrogen 2.932 N/A HIS 19.A N LYS 15.A O no hydrogen 2.890 N/A LYS 20.A N LEU 16.A O no hydrogen 2.852 N/A GLU 21.A N LEU 17.A O no hydrogen 2.983 N/A ILE 22.A N GLU 18.A O no hydrogen 2.915 N/A ASP 23.A N HIS 19.A O no hydrogen 2.895 N/A GLY 24.A N LYS 20.A O no hydrogen 2.961 N/A ARG 25.A N GLU 21.A O no hydrogen 2.885 N/A LEU 26.A N ILE 22.A O no hydrogen 2.850 N/A LYS 27.A N ASP 23.A O no hydrogen 2.915 N/A GLU 28.A N GLY 24.A O no hydrogen 2.961 N/A LEU 29.A N ARG 25.A O no hydrogen 2.929 N/A ARG 30.A N LEU 26.A O no hydrogen 2.933 N/A GLU 31.A N LYS 27.A O no hydrogen 2.921 N/A GLN 32.A N GLU 28.A O no hydrogen 2.933 N/A LEU 33.A N LEU 29.A O no hydrogen 2.895 N/A LYS 34.A N ARG 30.A O no hydrogen 2.949 N/A GLU 35.A N GLU 31.A O no hydrogen 2.985 N/A LEU 36.A N GLN 32.A O no hydrogen 2.924 N/A THR 37.A N LEU 33.A O no hydrogen 2.878 N/A THR 37.A OG1 LEU 33.A O no hydrogen 2.515 N/A LYS 38.A N LYS 34.A O no hydrogen 3.015 N/A LYS 38.A NZ LYS 34.A O no hydrogen 3.223 N/A GLN 39.A N GLU 35.A O no hydrogen 2.988 N/A TYR 40.A N LEU 36.A O no hydrogen 2.875 N/A GLU 41.A N THR 37.A O no hydrogen 2.960 N/A LYS 42.A N LYS 38.A O no hydrogen 2.976 N/A SER 43.A N GLN 39.A O no hydrogen 2.959 N/A SER 43.A OG TYR 40.A O no hydrogen 2.924 N/A GLU 44.A N TYR 40.A O no hydrogen 2.914 N/A ASN 45.A N GLU 41.A O no hydrogen 2.954 N/A ASN 45.A ND2 GLU 41.A O no hydrogen 2.413 N/A ASP 46.A N LYS 42.A O no hydrogen 2.922 N/A LEU 47.A N SER 43.A O no hydrogen 2.944 N/A LYS 48.A N GLU 44.A O no hydrogen 2.905 N/A ALA 49.A N ASN 45.A O no hydrogen 2.904 N/A ILE 56.A N LEU 100.A O no hydrogen 2.858 N/A GLY 58.A N VAL 98.A O no hydrogen 2.861 N/A GLU 59.A N LYS 72.A O no hydrogen 2.951 N/A VAL 60.A N THR 96.A O no hydrogen 3.011 N/A LEU 61.A N ILE 70.A O no hydrogen 2.481 N/A GLN 63.A NE2 THR 65.A O no hydrogen 2.930 N/A LEU 64.A N LYS 68.A O no hydrogen 2.733 N/A THR 65.A N LYS 68.A O no hydrogen 3.100 N/A THR 65.A OG1 GLU 66.A OE1 no hydrogen 3.476 N/A GLU 66.A N GLU 66.A OE1 no hydrogen 2.832 N/A GLU 67.A N THR 65.A OG1 no hydrogen 3.052 N/A PHE 69.A N VAL 81.A O no hydrogen 3.109 N/A ILE 70.A N LYS 62.A O no hydrogen 2.911 N/A VAL 71.A N TYR 79.A O no hydrogen 3.225 N/A LYS 72.A N GLU 59.A O no hydrogen 2.837 N/A ALA 73.A N PRO 77.A O no hydrogen 3.172 N/A THR 74.A OG1 ASN 75.A OD1 no hydrogen 3.119 N/A TYR 79.A N VAL 71.A O no hydrogen 3.024 N/A VAL 81.A N PHE 69.A O no hydrogen 3.173 N/A CYS 83.A SG GLU 67.A OE1 no hydrogen 3.477 N/A CYS 83.A SG GLU 67.A OE2 no hydrogen 3.263 N/A ARG 84.A NH1 MET 108.A O no hydrogen 2.354 N/A LYS 91.A N ASP 88.A O no hydrogen 2.587 N/A LEU 92.A N LYS 89.A O no hydrogen 3.326 N/A LYS 93.A N LYS 91.A O no hydrogen 2.721 N/A GLY 95.A N VAL 60.A O no hydrogen 3.018 N/A THR 96.A N LYS 93.A O no hydrogen 3.266 N/A THR 96.A OG1 LYS 91.A O no hydrogen 3.555 N/A THR 96.A OG1 LYS 93.A O no hydrogen 2.775 N/A VAL 98.A N GLY 58.A O no hydrogen 2.543 N/A ALA 99.A N ARG 109.A O no hydrogen 2.813 N/A LEU 100.A N ILE 56.A O no hydrogen 2.700 N/A ASP 101.A N THR 106.A O no hydrogen 2.879 N/A THR 103.A N ASP 101.A OD2 no hydrogen 3.112 N/A THR 103.A OG1 ASP 101.A OD2 no hydrogen 2.970 N/A THR 104.A N ASP 101.A OD2 no hydrogen 2.512 N/A THR 104.A OG1 ASP 101.A OD2 no hydrogen 2.446 N/A THR 106.A OG1 GLY 82.A O no hydrogen 2.445 N/A ILE 107.A N GLY 82.A O no hydrogen 3.422 N/A MET 108.A N ALA 99.A O no hydrogen 2.707 N/A LEU 111.A N ARG 97.A O no hydrogen 2.704 N/A VAL 119.A N ASP 116.A O no hydrogen 3.442 N/A ASN 121.A ND2 LEU 118.A O no hydrogen 2.638 N/A SER 123.A OG VAL 119.A O no hydrogen 2.807 N/A HIS 124.A ND1 ASN 121.A O no hydrogen 2.662 N/A ASP 126.A N ASN 194.A O no hydrogen 2.908 N/A GLY 128.A N ASP 126.A O no hydrogen 2.698 N/A SER 131.A OG SER 131.A O no hydrogen 2.374 N/A SER 133.A OG GLU 134.A OE1 no hydrogen 2.950 N/A GLN 141.A N GLN 141.A OE1 no hydrogen 2.844 N/A ILE 142.A N LEU 138.A O no hydrogen 2.708 N/A ARG 143.A N SER 139.A O no hydrogen 2.889 N/A ARG 143.A NE ARG 143.A O no hydrogen 3.161 N/A ARG 143.A NH2 GLU 150.A OE2 no hydrogen 3.309 N/A GLU 144.A N GLU 140.A O no hydrogen 2.924 N/A LEU 145.A N GLN 141.A O no hydrogen 2.912 N/A ARG 146.A N ILE 142.A O no hydrogen 2.867 N/A ARG 146.A N ARG 143.A O no hydrogen 3.248 N/A ARG 146.A NH2 SER 189.A OG no hydrogen 3.296 N/A VAL 148.A N LEU 145.A O no hydrogen 3.275 N/A GLU 150.A N ARG 146.A O no hydrogen 2.883 N/A LEU 151.A N GLU 147.A O no hydrogen 2.944 N/A THR 154.A N GLU 150.A O no hydrogen 3.001 N/A THR 154.A OG1 GLU 150.A O no hydrogen 2.950 N/A LEU 158.A N ASN 155.A OD1 no hydrogen 3.072 N/A ARG 161.A N GLU 157.A O no hydrogen 2.847 N/A VAL 162.A N LEU 158.A O no hydrogen 2.915 N/A GLY 163.A N PHE 159.A O no hydrogen 2.791 N/A LYS 168.A NZ ASP 265.A OD1 no hydrogen 3.194 N/A LEU 171.A N ARG 297.A O no hydrogen 2.896 N/A LEU 172.A N MET 277.A O no hydrogen 3.482 N/A TYR 173.A N ILE 299.A O no hydrogen 2.660 N/A LYS 180.A NZ GLY 174.A O no hydrogen 2.996 N/A LYS 180.A NZ PRO 175.A O no hydrogen 3.497 N/A LEU 183.A N GLY 179.A O no hydrogen 2.927 N/A ALA 184.A N LYS 180.A O no hydrogen 2.908 N/A ARG 185.A N THR 181.A O no hydrogen 2.859 N/A ALA 186.A N LEU 182.A O no hydrogen 2.943 N/A VAL 187.A N LEU 183.A O no hydrogen 2.919 N/A ALA 188.A N ALA 184.A O no hydrogen 2.860 N/A SER 189.A N ALA 186.A O no hydrogen 3.307 N/A CYS 193.A N ASP 192.A OD1 no hydrogen 2.691 N/A ASN 194.A ND2 PRO 227.A O no hydrogen 2.638 N/A PHE 195.A N ASN 194.A OD1 no hydrogen 2.499 N/A SER 200.A OG VAL 199.A O no hydrogen 2.790 N/A SER 200.A OG ASP 233.A O no hydrogen 2.362 N/A SER 201.A OG VAL 199.A O no hydrogen 2.976 N/A SER 211.A OG ILE 203.A O no hydrogen 2.888 N/A ALA 212.A N ILE 208.A O no hydrogen 3.507 N/A LEU 214.A N GLU 210.A O no hydrogen 2.894 N/A ILE 215.A N SER 211.A O no hydrogen 2.913 N/A ARG 216.A N ALA 212.A O no hydrogen 2.916 N/A GLU 217.A N ARG 213.A O no hydrogen 2.885 N/A MET 218.A N LEU 214.A O no hydrogen 2.913 N/A PHE 219.A N ILE 215.A O no hydrogen 2.934 N/A ASN 220.A N ARG 216.A O no hydrogen 2.904 N/A TYR 221.A N GLU 217.A O no hydrogen 2.949 N/A ALA 222.A N MET 218.A O no hydrogen 2.859 N/A ARG 223.A N PHE 219.A O no hydrogen 2.904 N/A ARG 223.A NH2 ASP 268.A OD1 no hydrogen 2.998 N/A HIS 225.A ND1 TYR 221.A O no hydrogen 3.076 N/A MET 232.A N ILE 276.A O no hydrogen 2.788 N/A ASP 236.A N ASP 236.A OD1 no hydrogen 2.460 N/A ARG 242.A NE THR 284.A OG1 no hydrogen 3.247 N/A ARG 242.A NH1 ASP 250.A O no hydrogen 2.571 N/A ARG 242.A NH2 ASP 250.A O no hydrogen 2.760 N/A PHE 243.A N ARG 241.A O no hydrogen 2.719 N/A GLY 246.A N SER 244.A O no hydrogen 2.665 N/A SER 248.A N THR 247.A OG1 no hydrogen 2.660 N/A ALA 249.A N THR 247.A O no hydrogen 2.553 N/A ARG 251.A NH2 ASP 286.A OD1 no hydrogen 2.828 N/A GLU 252.A N GLU 252.A OE1 no hydrogen 2.948 N/A ARG 255.A N ARG 251.A O no hydrogen 2.903 N/A ARG 255.A NE ARG 251.A O no hydrogen 3.183 N/A THR 256.A N GLU 252.A O no hydrogen 2.941 N/A THR 256.A OG1 GLU 252.A O no hydrogen 2.808 N/A THR 256.A OG1 ILE 253.A O no hydrogen 2.616 N/A LEU 257.A N ILE 253.A O no hydrogen 2.947 N/A MET 258.A N GLN 254.A O no hydrogen 2.884 N/A GLU 259.A N ARG 255.A O no hydrogen 2.936 N/A LEU 260.A N THR 256.A O no hydrogen 2.893 N/A LEU 261.A N LEU 257.A O no hydrogen 2.958 N/A ASN 262.A N MET 258.A O no hydrogen 2.893 N/A GLN 263.A N GLU 259.A O no hydrogen 2.870 N/A GLN 263.A NE2 ALA 212.A O no hydrogen 3.214 N/A MET 264.A N LEU 260.A O no hydrogen 2.969 N/A ASP 265.A N LEU 261.A O no hydrogen 3.150 N/A THR 269.A OG1 MET 264.A O no hydrogen 2.287 N/A THR 269.A OG1 GLY 266.A O no hydrogen 3.508 N/A LYS 274.A N CYS 228.A O no hydrogen 2.692 N/A LYS 274.A NZ ILE 149.A O no hydrogen 2.824 N/A ILE 276.A N ILE 230.A O no hydrogen 2.686 N/A THR 279.A N MET 277.A O no hydrogen 3.105 N/A ASN 280.A ND2 GLY 174.A O no hydrogen 2.364 N/A ARG 281.A NH1 ASP 385.A O no hydrogen 2.446 N/A ARG 281.A NH2 ASP 385.A O no hydrogen 3.074 N/A THR 284.A OG1 PHE 243.A O no hydrogen 3.568 N/A LEU 285.A N ASP 283.A O no hydrogen 2.704 N/A ARG 291.A N PRO 287.A O no hydrogen 2.929 N/A ARG 291.A NE ALA 288.A O no hydrogen 2.560 N/A ARG 297.A N ASP 296.A OD1 no hydrogen 2.758 N/A ARG 297.A NH1 GLU 144.A OE2 no hydrogen 2.549 N/A ARG 297.A NH2 GLU 144.A OE2 no hydrogen 3.041 N/A ILE 299.A N LEU 171.A O no hydrogen 2.774 N/A ILE 301.A N TYR 173.A O no hydrogen 3.151 N/A ASN 305.A ND2 ASP 302.A O no hydrogen 2.702 N/A ASN 305.A ND2 ASP 302.A OD1 no hydrogen 3.362 N/A ARG 309.A NH1 SER 335.A O no hydrogen 2.961 N/A ARG 309.A NH1 ASP 336.A OD1 no hydrogen 2.394 N/A ASP 311.A N GLN 307.A O no hydrogen 3.381 N/A ILE 312.A N ALA 308.A O no hydrogen 2.906 N/A LEU 313.A N ARG 309.A O no hydrogen 2.887 N/A LYS 314.A N LEU 310.A O no hydrogen 2.880 N/A ILE 315.A N ASP 311.A O no hydrogen 2.913 N/A HIS 316.A N ILE 312.A O no hydrogen 2.929 N/A HIS 316.A ND1 ILE 312.A O no hydrogen 2.851 N/A ALA 317.A N LEU 313.A O no hydrogen 2.809 N/A ILE 320.A N GLY 318.A O no hydrogen 2.639 N/A THR 321.A OG1 ASP 360.A O no hydrogen 2.947 N/A LYS 322.A NZ ALA 317.A O no hydrogen 2.970 N/A HIS 323.A N VAL 362.A O no hydrogen 2.781 N/A GLU 329.A N GLU 329.A OE1 no hydrogen 2.767 N/A ILE 331.A N TYR 328.A O no hydrogen 3.123 N/A VAL 332.A N TYR 328.A O no hydrogen 2.914 N/A LYS 333.A N GLU 329.A O no hydrogen 2.896 N/A LYS 333.A NZ GLU 306.A OE1 no hydrogen 2.692 N/A LEU 334.A N ILE 331.A O no hydrogen 3.171 N/A ASN 339.A ND2 GLY 337.A O no hydrogen 3.602 N/A LEU 343.A N ASN 339.A O no hydrogen 3.147 N/A ARG 344.A N GLY 340.A O no hydrogen 2.944 N/A ASN 345.A N ALA 341.A O no hydrogen 2.919 N/A VAL 346.A N ASP 342.A O no hydrogen 2.865 N/A CYS 347.A N LEU 343.A O no hydrogen 2.956 N/A CYS 347.A SG LEU 343.A O no hydrogen 3.413 N/A THR 348.A N ARG 344.A O no hydrogen 2.934 N/A THR 348.A OG1 ARG 344.A O no hydrogen 2.751 N/A GLU 349.A N ASN 345.A O no hydrogen 2.864 N/A ALA 350.A N VAL 346.A O no hydrogen 2.905 N/A GLY 351.A N CYS 347.A O no hydrogen 2.948 N/A MET 352.A N THR 348.A O no hydrogen 2.882 N/A PHE 353.A N GLU 349.A O no hydrogen 2.893 N/A ALA 354.A N ALA 350.A O no hydrogen 2.915 N/A ILE 355.A N GLY 351.A O no hydrogen 2.935 N/A ARG 356.A N MET 352.A O no hydrogen 3.343 N/A ARG 356.A NH1 GLU 349.A OE2 no hydrogen 3.372 N/A ASP 358.A N ILE 355.A O no hydrogen 3.392 N/A HIS 359.A N ALA 354.A O no hydrogen 2.840 N/A HIS 359.A ND1 PHE 361.A O no hydrogen 2.438 N/A VAL 362.A N THR 321.A O no hydrogen 3.204 N/A PHE 367.A N VAL 363.A O no hydrogen 3.412 N/A MET 368.A N GLN 364.A O no hydrogen 2.931 N/A LYS 369.A N GLU 365.A O no hydrogen 2.899 N/A LYS 369.A NZ GLU 365.A O no hydrogen 3.170 N/A LYS 369.A NZ ASP 366.A OD1 no hydrogen 2.739 N/A ALA 370.A N ASP 366.A O no hydrogen 2.913 N/A VAL 371.A N PHE 367.A O no hydrogen 2.905 N/A ARG 372.A N MET 368.A O no hydrogen 2.940 N/A LYS 373.A N LYS 369.A O no hydrogen 2.931 N/A VAL 374.A N ALA 370.A O no hydrogen 2.903 N/A ALA 375.A N VAL 371.A O no hydrogen 2.880 N/A ASP 376.A N ARG 372.A O no hydrogen 2.956 N/A SER 377.A N LYS 373.A O no hydrogen 2.910 N/A SER 377.A OG LYS 373.A O no hydrogen 3.218 N/A SER 377.A OG VAL 374.A O no hydrogen 2.682 N/A LYS 378.A N VAL 374.A O no hydrogen 2.872 N/A LYS 378.A NZ ASP 336.A O no hydrogen 3.011 N/A LYS 379.A N ALA 375.A O no hydrogen 2.937 N/A LYS 379.A NZ ASP 376.A O no hydrogen 3.209 N/A LYS 387.A NZ ASP 283.A OD1 no hydrogen 3.076 N/A