Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7wu3_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 TYR 24.A OH no hydrogen 2.274 N/A SER 4.A N SER 2.A OG no hydrogen 3.023 N/A SER 4.A OG SER 8.A OG no hydrogen 3.009 N/A SER 4.A OG HIS 248.A ND1 no hydrogen 2.742 N/A MET 7.A N SER 4.A O no hydrogen 3.104 N/A SER 8.A OG SER 4.A O no hydrogen 2.479 N/A SER 8.A OG SER 4.A OG no hydrogen 3.009 N/A PHE 16.A N PRO 12.A O no hydrogen 2.838 N/A VAL 19.A N ILE 15.A O no hydrogen 3.005 N/A LYS 20.A N PHE 16.A O no hydrogen 2.942 N/A TRP 21.A N PRO 17.A O no hydrogen 2.986 N/A ILE 22.A N VAL 18.A O no hydrogen 3.175 N/A THR 23.A N VAL 19.A O no hydrogen 2.806 N/A THR 23.A OG1 SER 2.A O no hydrogen 2.718 N/A THR 23.A OG1 VAL 19.A O no hydrogen 2.958 N/A TYR 24.A N LYS 20.A O no hydrogen 2.913 N/A VAL 25.A N TRP 21.A O no hydrogen 3.309 N/A GLY 26.A N ILE 22.A O no hydrogen 3.007 N/A LEU 27.A N THR 23.A O no hydrogen 2.935 N/A GLY 28.A N TYR 24.A O no hydrogen 3.192 N/A ILE 29.A N VAL 25.A O no hydrogen 3.295 N/A SER 30.A N GLY 26.A O no hydrogen 3.064 N/A SER 30.A OG GLY 26.A O no hydrogen 3.349 N/A SER 30.A OG LEU 27.A O no hydrogen 3.015 N/A ILE 31.A N LEU 27.A O no hydrogen 2.859 N/A SER 33.A N ILE 29.A O no hydrogen 2.901 N/A SER 33.A OG ILE 29.A O no hydrogen 2.525 N/A LEU 34.A N SER 30.A O no hydrogen 2.772 N/A ILE 35.A N ILE 31.A O no hydrogen 3.064 N/A LEU 36.A N GLY 32.A O no hydrogen 3.188 N/A CYS 37.A N SER 33.A O no hydrogen 3.018 N/A LEU 38.A N LEU 34.A O no hydrogen 3.043 N/A ILE 39.A N ILE 35.A O no hydrogen 3.177 N/A ILE 40.A N LEU 36.A O no hydrogen 2.945 N/A GLU 41.A N CYS 37.A O no hydrogen 2.942 N/A ALA 42.A N LEU 38.A O no hydrogen 2.889 N/A LEU 43.A N ILE 39.A O no hydrogen 2.921 N/A PHE 44.A N ILE 40.A O no hydrogen 2.970 N/A SER 51.A N LYS 49.A O no hydrogen 2.941 N/A HIS 55.A N SER 51.A O no hydrogen 2.997 N/A THR 56.A N GLN 52.A O no hydrogen 3.393 N/A ARG 57.A N THR 53.A O no hydrogen 3.326 N/A ARG 58.A N SER 54.A O no hydrogen 3.301 N/A ILE 59.A N HIS 55.A O no hydrogen 3.071 N/A CYS 60.A N THR 56.A O no hydrogen 3.257 N/A CYS 60.A SG THR 56.A O no hydrogen 3.469 N/A MET 61.A N ARG 57.A O no hydrogen 2.870 N/A VAL 62.A N ARG 58.A O no hydrogen 3.046 N/A ASN 63.A N ILE 59.A O no hydrogen 3.071 N/A ILE 64.A N CYS 60.A O no hydrogen 3.010 N/A ALA 65.A N MET 61.A O no hydrogen 2.854 N/A LEU 66.A N VAL 62.A O no hydrogen 2.484 N/A SER 67.A N ASN 63.A O no hydrogen 2.874 N/A SER 67.A OG ASN 63.A O no hydrogen 3.003 N/A SER 67.A OG SER 98.A OG no hydrogen 2.990 N/A SER 67.A OG TYR 135.A OH no hydrogen 3.396 N/A LEU 68.A N ILE 64.A O no hydrogen 2.983 N/A LEU 69.A N ALA 65.A O no hydrogen 3.131 N/A ILE 70.A N LEU 66.A O no hydrogen 3.282 N/A ALA 71.A N SER 67.A O no hydrogen 2.994 N/A ASP 72.A N LEU 68.A O no hydrogen 2.971 N/A VAL 73.A N LEU 69.A O no hydrogen 3.149 N/A TRP 74.A N ILE 70.A O no hydrogen 3.132 N/A PHE 75.A N ALA 71.A O no hydrogen 3.014 N/A ILE 76.A N ASP 72.A O no hydrogen 3.179 N/A VAL 77.A N VAL 73.A O no hydrogen 3.306 N/A GLY 78.A N TRP 74.A O no hydrogen 3.331 N/A ALA 79.A N PHE 75.A O no hydrogen 3.219 N/A THR 80.A N ILE 76.A O no hydrogen 3.162 N/A THR 80.A OG1 VAL 77.A O no hydrogen 2.650 N/A VAL 81.A N VAL 77.A O no hydrogen 3.242 N/A CYS 85.A SG GLY 78.A O no hydrogen 3.471 N/A THR 86.A N SER 82.A O no hydrogen 3.215 N/A ALA 87.A N GLY 83.A O no hydrogen 2.936 N/A ALA 88.A N VAL 84.A O no hydrogen 3.310 N/A ALA 88.A N CYS 85.A O no hydrogen 3.146 N/A VAL 89.A N THR 86.A O no hydrogen 3.429 N/A THR 92.A N ALA 88.A O no hydrogen 2.928 N/A THR 92.A OG1 ALA 88.A O no hydrogen 2.897 N/A HIS 93.A N VAL 89.A O no hydrogen 2.866 N/A HIS 93.A ND1 SER 142.A OG no hydrogen 3.139 N/A PHE 94.A N PHE 90.A O no hydrogen 2.911 N/A PHE 95.A N PHE 91.A O no hydrogen 2.776 N/A TYR 96.A N THR 92.A O no hydrogen 3.064 N/A TYR 96.A OH ASP 72.A OD1 no hydrogen 3.068 N/A LEU 97.A N HIS 93.A O no hydrogen 3.203 N/A SER 98.A N PHE 94.A O no hydrogen 2.846 N/A SER 98.A OG SER 67.A OG no hydrogen 2.990 N/A SER 98.A OG PHE 95.A O no hydrogen 2.497 N/A LEU 99.A N PHE 95.A O no hydrogen 2.781 N/A PHE 100.A N TYR 96.A O no hydrogen 2.832 N/A PHE 101.A N LEU 97.A O no hydrogen 2.734 N/A TRP 102.A N SER 98.A O no hydrogen 2.844 N/A MET 103.A N LEU 99.A O no hydrogen 2.949 N/A LEU 104.A N PHE 100.A O no hydrogen 2.984 N/A MET 105.A N PHE 101.A O no hydrogen 3.104 N/A LEU 106.A N TRP 102.A O no hydrogen 3.202 N/A GLY 107.A N MET 103.A O no hydrogen 3.086 N/A ILE 108.A N LEU 104.A O no hydrogen 2.639 N/A LEU 109.A N MET 105.A O no hydrogen 2.805 N/A LEU 110.A N LEU 106.A O no hydrogen 2.992 N/A ALA 111.A N GLY 107.A O no hydrogen 2.947 N/A TYR 112.A N ILE 108.A O no hydrogen 2.667 N/A TYR 112.A OH HIS 119.A O no hydrogen 2.344 N/A ARG 113.A N LEU 109.A O no hydrogen 2.957 N/A ARG 113.A NH1 HIS 119.A O no hydrogen 3.524 N/A ARG 113.A NH2 VAL 117.A O no hydrogen 2.994 N/A ILE 114.A N ALA 111.A O no hydrogen 3.174 N/A ILE 115.A N ALA 111.A O no hydrogen 2.811 N/A LEU 116.A N TYR 112.A O no hydrogen 3.035 N/A MET 126.A N ALA 122.A O no hydrogen 3.149 N/A MET 127.A N GLN 123.A O no hydrogen 2.797 N/A ALA 128.A N HIS 124.A O no hydrogen 3.076 N/A VAL 129.A N LEU 125.A O no hydrogen 3.187 N/A GLY 130.A N MET 126.A O no hydrogen 3.319 N/A PHE 131.A N MET 127.A O no hydrogen 3.163 N/A CYS 132.A N ALA 128.A O no hydrogen 2.748 N/A LEU 133.A N VAL 129.A O no hydrogen 2.941 N/A GLY 134.A N GLY 130.A O no hydrogen 2.835 N/A TYR 135.A N PHE 131.A O no hydrogen 3.328 N/A TYR 135.A OH SER 67.A OG no hydrogen 3.396 N/A GLY 136.A N CYS 132.A O no hydrogen 2.938 N/A LEU 139.A N TYR 135.A O no hydrogen 3.117 N/A ILE 140.A N GLY 136.A O no hydrogen 2.843 N/A ILE 141.A N CYS 137.A O no hydrogen 3.093 N/A SER 142.A N PRO 138.A O no hydrogen 3.051 N/A SER 142.A OG HIS 93.A ND1 no hydrogen 3.139 N/A SER 142.A OG PRO 138.A O no hydrogen 3.045 N/A VAL 143.A N LEU 139.A O no hydrogen 3.112 N/A ILE 144.A N ILE 140.A O no hydrogen 3.191 N/A THR 145.A N ILE 141.A O no hydrogen 3.216 N/A THR 145.A OG1 ILE 141.A O no hydrogen 2.853 N/A ILE 146.A N SER 142.A O no hydrogen 3.369 N/A ALA 147.A N VAL 143.A O no hydrogen 3.042 N/A VAL 148.A N THR 145.A O no hydrogen 3.275 N/A THR 149.A N THR 145.A O no hydrogen 3.051 N/A THR 149.A OG1 THR 154.A OG1 no hydrogen 2.210 N/A THR 149.A OG1 SER 169.A OG no hydrogen 2.931 N/A GLN 150.A N ILE 146.A O no hydrogen 3.408 N/A SER 152.A OG THR 154.A OG1 no hydrogen 3.400 N/A ASN 153.A N GLN 150.A O no hydrogen 3.060 N/A THR 154.A OG1 THR 149.A O no hydrogen 3.428 N/A THR 154.A OG1 THR 149.A OG1 no hydrogen 2.210 N/A THR 154.A OG1 SER 152.A OG no hydrogen 3.400 N/A LYS 156.A NZ SER 82.A O no hydrogen 3.359 N/A LYS 156.A NZ SER 82.A OG no hydrogen 3.089 N/A ARG 157.A NH2 PRO 9.A O no hydrogen 2.897 N/A VAL 160.A N ARG 157.A O no hydrogen 3.487 N/A CYS 161.A N ARG 157.A O no hydrogen 3.458 N/A CYS 161.A SG GLY 78.A O no hydrogen 3.863 N/A CYS 161.A SG VAL 160.A O no hydrogen 3.037 N/A ASN 164.A ND2 THR 154.A O no hydrogen 2.801 N/A SER 166.A OG TRP 165.A O no hydrogen 2.548 N/A SER 169.A OG THR 149.A OG1 no hydrogen 2.931 N/A SER 169.A OG THR 154.A OG1 no hydrogen 3.335 N/A LYS 170.A NZ GLY 168.A O no hydrogen 2.520 N/A LEU 172.A N ASN 164.A O no hydrogen 3.219 N/A PHE 175.A N LEU 172.A O no hydrogen 2.999 N/A VAL 176.A N LEU 172.A O no hydrogen 2.970 N/A VAL 177.A N LEU 173.A O no hydrogen 3.018 N/A ALA 179.A N PHE 175.A O no hydrogen 3.415 N/A LEU 180.A N VAL 176.A O no hydrogen 2.818 N/A ALA 181.A N VAL 177.A O no hydrogen 2.878 N/A ILE 182.A N PRO 178.A O no hydrogen 2.964 N/A VAL 183.A N ALA 179.A O no hydrogen 3.181 N/A ALA 184.A N LEU 180.A O no hydrogen 2.858 N/A VAL 185.A N ALA 181.A O no hydrogen 3.028 N/A ASN 186.A N ILE 182.A O no hydrogen 2.784 N/A ASN 186.A ND2 MET 103.A O no hydrogen 3.469 N/A ASN 186.A ND2 LEU 228.A O no hydrogen 2.669 N/A PHE 187.A N VAL 183.A O no hydrogen 2.672 N/A VAL 188.A N ALA 184.A O no hydrogen 3.194 N/A VAL 189.A N VAL 185.A O no hydrogen 3.033 N/A VAL 190.A N ASN 186.A O no hydrogen 2.902 N/A LEU 191.A N PHE 187.A O no hydrogen 2.964 N/A LEU 192.A N VAL 188.A O no hydrogen 2.982 N/A VAL 193.A N VAL 189.A O no hydrogen 3.108 N/A LEU 194.A N VAL 190.A O no hydrogen 2.991 N/A THR 195.A N LEU 191.A O no hydrogen 3.076 N/A THR 195.A OG1 LEU 191.A O no hydrogen 2.751 N/A LYS 196.A N LEU 192.A O no hydrogen 3.393 N/A LEU 197.A N VAL 193.A O no hydrogen 3.121 N/A THR 201.A OG1 THR 201.A O no hydrogen 2.583 N/A ARG 205.A N VAL 202.A O no hydrogen 3.360 N/A THR 213.A OG1 ASP 210.A O no hydrogen 2.740 N/A ILE 214.A N ASP 210.A O no hydrogen 3.037 N/A ILE 215.A N LYS 211.A O no hydrogen 3.048 N/A ARG 216.A N ALA 212.A O no hydrogen 3.295 N/A ARG 216.A NH2 LEU 197.A O no hydrogen 3.391 N/A VAL 217.A N THR 213.A O no hydrogen 2.799 N/A GLY 218.A N ILE 214.A O no hydrogen 2.511 N/A LYS 219.A N ILE 215.A O no hydrogen 3.212 N/A SER 220.A N ARG 216.A O no hydrogen 3.497 N/A SER 220.A OG ARG 216.A O no hydrogen 3.191 N/A LEU 221.A N VAL 217.A O no hydrogen 3.007 N/A LEU 222.A N GLY 218.A O no hydrogen 3.057 N/A ILE 223.A N LYS 219.A O no hydrogen 3.350 N/A LEU 224.A N SER 220.A O no hydrogen 2.956 N/A THR 225.A N LEU 221.A O no hydrogen 3.218 N/A THR 225.A OG1 LEU 221.A O no hydrogen 3.228 N/A THR 225.A OG1 LEU 222.A O no hydrogen 3.048 N/A LEU 228.A N LEU 224.A O no hydrogen 3.003 N/A GLY 229.A N PRO 226.A O no hydrogen 3.333 N/A LEU 230.A N THR 225.A O no hydrogen 2.750 N/A TRP 232.A N GLY 229.A O no hydrogen 3.305 N/A GLY 233.A N LEU 230.A O no hydrogen 3.142 N/A GLY 235.A N TRP 232.A O no hydrogen 3.139 N/A GLY 237.A N PHE 234.A O no hydrogen 3.142 N/A THR 238.A N PHE 234.A O no hydrogen 3.406 N/A ILE 239.A N GLY 235.A O no hydrogen 2.934 N/A SER 242.A N THR 238.A O no hydrogen 2.932 N/A SER 242.A OG PHE 10.A O no hydrogen 2.703 N/A SER 242.A OG SER 242.A O no hydrogen 2.363 N/A ALA 246.A N ASN 244.A OD1 no hydrogen 3.094 N/A HIS 248.A N ASN 244.A O no hydrogen 3.196 N/A VAL 249.A N LEU 245.A O no hydrogen 3.133 N/A PHE 251.A N TRP 247.A O no hydrogen 3.442 N/A ALA 252.A N HIS 248.A O no hydrogen 3.147 N/A LEU 253.A N VAL 249.A O no hydrogen 2.955 N/A LEU 254.A N ILE 250.A O no hydrogen 3.167 N/A ASN 255.A N PHE 251.A O no hydrogen 3.344 N/A ALA 256.A N ALA 252.A O no hydrogen 3.059 N/A PHE 257.A N LEU 253.A O no hydrogen 3.026 N/A GLN 258.A N ASN 255.A O no hydrogen 3.181 N/A GLN 258.A NE2 PRO 226.A O no hydrogen 3.109 N/A PHE 261.A N PHE 257.A O no hydrogen 2.776 N/A ILE 262.A N GLN 258.A O no hydrogen 2.723 N/A LEU 263.A N GLY 259.A O no hydrogen 3.238 N/A CYS 264.A N PHE 260.A O no hydrogen 2.919 N/A PHE 265.A N PHE 261.A O no hydrogen 2.766 N/A GLY 266.A N ILE 262.A O no hydrogen 2.689 N/A LEU 268.A N LEU 263.A O no hydrogen 3.077 N/A ASP 270.A N ILE 267.A O no hydrogen 3.187 N/A LEU 273.A N ASP 270.A OD1 no hydrogen 2.924 N/A ARG 274.A N ASP 270.A O no hydrogen 2.930 N/A LEU 276.A N LYS 272.A O no hydrogen 3.204 N/A LEU 277.A N LEU 273.A O no hydrogen 2.731 N/A PHE 278.A N ARG 274.A O no hydrogen 2.949 N/A ASN 279.A N GLN 275.A O no hydrogen 3.066 N/A LYS 280.A N LEU 276.A O no hydrogen 3.179 N/A