Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x01_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N GLU 25.A O no hydrogen 2.440 N/A VAL 5.A N GLU 27.A O no hydrogen 3.283 N/A ILE 7.A N VAL 5.A O no hydrogen 3.028 N/A SER 11.A OG ASP 8.A O no hydrogen 3.232 N/A LEU 14.A N SER 11.A O no hydrogen 3.411 N/A LEU 17.A N PHE 13.A O no hydrogen 2.934 N/A GLN 18.A N LEU 14.A O no hydrogen 2.891 N/A ARG 19.A N LYS 15.A O no hydrogen 2.910 N/A ALA 20.A N ALA 16.A O no hydrogen 2.913 N/A TYR 21.A N LEU 17.A O no hydrogen 2.819 N/A GLU 27.A N VAL 3.A O no hydrogen 2.956 N/A ARG 29.A N VAL 5.A O no hydrogen 2.909 N/A VAL 31.A N ASP 6.A OD1 no hydrogen 2.937 N/A THR 32.A OG1 ASP 6.A OD2 no hydrogen 3.245 N/A ASN 38.A ND2 SER 193.A O no hydrogen 3.261 N/A PHE 42.A N ALA 39.A O no hydrogen 3.195 N/A SER 43.A N ALA 39.A O no hydrogen 2.988 N/A SER 43.A OG ALA 39.A O no hydrogen 3.118 N/A HIS 44.A N ARG 40.A O no hydrogen 2.837 N/A LEU 45.A N ALA 41.A O no hydrogen 3.401 N/A ALA 46.A N PHE 42.A O no hydrogen 2.962 N/A LYS 48.A NZ HIS 44.A O no hydrogen 3.262 N/A LEU 49.A N LEU 45.A O no hydrogen 2.934 N/A ILE 50.A N ALA 46.A O no hydrogen 2.942 N/A GLU 51.A N ILE 47.A O no hydrogen 2.904 N/A GLN 52.A N LYS 48.A O no hydrogen 2.868 N/A GLU 53.A N LEU 49.A O no hydrogen 2.946 N/A GLU 53.A N ILE 50.A O no hydrogen 3.270 N/A ILE 54.A N GLU 51.A O no hydrogen 3.302 N/A SER 58.A OG ASP 55.A O no hydrogen 3.517 N/A SER 58.A OG ASP 55.A OD1 no hydrogen 2.838 N/A SER 58.A OG ASP 55.A OD2 no hydrogen 3.283 N/A ILE 60.A N LYS 76.A O no hydrogen 3.070 N/A LEU 61.A N VAL 146.A O no hydrogen 2.821 N/A ILE 63.A N ILE 148.A O no hydrogen 3.484 N/A SER 65.A OG ASP 62.A OD2 no hydrogen 2.646 N/A ARG 69.A N ALA 66.A O no hydrogen 3.007 N/A ARG 70.A N PRO 67.A O no hydrogen 3.268 N/A ARG 70.A NE ASP 62.A OD2 no hydrogen 2.763 N/A SER 73.A OG GLU 51.A OE2 no hydrogen 3.479 N/A ASP 74.A N SER 73.A OG no hydrogen 2.580 N/A ARG 75.A NH2 GLU 51.A O no hydrogen 3.253 N/A LYS 76.A NZ ASP 57.A OD1 no hydrogen 3.405 N/A TYR 77.A OH GLU 51.A OE2 no hydrogen 2.297 N/A HIS 78.A N ILE 60.A O no hydrogen 2.839 N/A HIS 78.A ND1 PRO 130.A O no hydrogen 2.852 N/A CYS 79.A N THR 131.A O no hydrogen 3.424 N/A VAL 80.A N ASP 62.A O no hydrogen 2.870 N/A CYS 81.A SG SER 65.A O no hydrogen 3.387 N/A ARG 84.A N ASP 88.A OD2 no hydrogen 3.153 N/A ARG 84.A NH1 MET 83.A O no hydrogen 3.285 N/A SER 85.A N ASP 88.A OD2 no hydrogen 3.320 N/A SER 85.A OG GLU 87.A OE2 no hydrogen 3.365 N/A SER 85.A OG ASP 88.A OD1 no hydrogen 3.183 N/A GLU 87.A N SER 85.A OG no hydrogen 3.335 N/A ASP 88.A N SER 85.A O no hydrogen 3.446 N/A GLU 90.A N GLU 90.A OE1 no hydrogen 2.627 N/A LEU 92.A N ASP 88.A O no hydrogen 2.954 N/A ALA 93.A N PRO 89.A O no hydrogen 2.921 N/A ASN 94.A N GLU 90.A O no hydrogen 2.910 N/A ASN 94.A N ARG 91.A O no hydrogen 3.210 N/A TYR 95.A N ARG 91.A O no hydrogen 2.941 N/A ALA 96.A N LEU 92.A O no hydrogen 2.928 N/A ARG 97.A N ALA 93.A O no hydrogen 2.866 N/A LYS 98.A N ASN 94.A O no hydrogen 3.049 N/A LEU 99.A N TYR 95.A O no hydrogen 2.867 N/A ALA 100.A N ALA 96.A O no hydrogen 2.901 N/A SER 101.A N ARG 97.A O no hydrogen 2.904 N/A ARG 109.A NH2 MET 72.A O no hydrogen 2.900 N/A LYS 114.A N ASN 110.A O no hydrogen 2.946 N/A ILE 115.A N ILE 111.A O no hydrogen 2.884 N/A GLY 116.A N SER 112.A O no hydrogen 2.938 N/A ASP 117.A N GLY 113.A O no hydrogen 2.884 N/A LEU 118.A N LYS 114.A O no hydrogen 2.899 N/A GLN 119.A N ILE 115.A O no hydrogen 2.932 N/A ALA 120.A N GLY 116.A O no hydrogen 2.906 N/A VAL 121.A N ASP 117.A O no hydrogen 2.914 N/A MET 122.A N LEU 118.A O no hydrogen 2.910 N/A ALA 123.A N GLN 119.A O no hydrogen 2.917 N/A VAL 124.A N ALA 120.A O no hydrogen 3.074 N/A THR 129.A OG1 PHE 132.A O no hydrogen 2.534 N/A THR 131.A OG1 ASP 117.A OD2 no hydrogen 3.474 N/A CYS 133.A SG HIS 78.A NE2 no hydrogen 3.223 N/A CYS 133.A SG CYS 79.A O no hydrogen 3.656 N/A CYS 140.A SG HIS 78.A NE2 no hydrogen 3.497 N/A CYS 140.A SG GLU 128.A OE1 no hydrogen 3.793 N/A CYS 140.A SG GLU 128.A OE2 no hydrogen 3.202 N/A GLN 142.A NE2 ARG 143.A O no hydrogen 3.647 N/A ALA 147.A N LEU 171.A O no hydrogen 3.242 N/A TYR 149.A N TYR 173.A O no hydrogen 2.935 N/A TYR 149.A OH SER 160.A OG no hydrogen 2.488 N/A TYR 149.A OH GLN 164.A OE1 no hydrogen 3.166 N/A ASP 151.A N VAL 175.A O no hydrogen 3.348 N/A SER 160.A N HIS 156.A O no hydrogen 3.083 N/A SER 160.A OG TYR 149.A OH no hydrogen 2.488 N/A LEU 161.A N ALA 157.A O no hydrogen 2.910 N/A TYR 162.A N PRO 158.A O no hydrogen 2.906 N/A HIS 163.A N THR 159.A O no hydrogen 2.966 N/A HIS 163.A N SER 160.A O no hydrogen 3.056 N/A HIS 163.A ND1 THR 159.A O no hydrogen 2.759 N/A GLN 164.A N SER 160.A O no hydrogen 3.325 N/A GLN 164.A N LEU 161.A O no hydrogen 3.292 N/A ALA 165.A N LEU 161.A O no hydrogen 2.921 N/A LYS 167.A N GLN 164.A O no hydrogen 3.202 N/A LYS 167.A NZ CYS 140.A O no hydrogen 2.441 N/A LYS 167.A NZ GLN 142.A O no hydrogen 3.288 N/A VAL 169.A N GLN 164.A O no hydrogen 3.412 N/A ARG 170.A N ASP 145.A O no hydrogen 3.213 N/A ARG 170.A NH2 ALA 165.A O no hydrogen 3.404 N/A ALA 172.A N ILE 284.A O no hydrogen 2.906 N/A TYR 173.A N ALA 147.A O no hydrogen 3.128 N/A TRP 174.A N LYS 282.A O no hydrogen 2.933 N/A VAL 175.A N TYR 149.A O no hydrogen 3.263 N/A GLY 176.A N VAL 280.A O no hydrogen 3.013 N/A PHE 177.A N TYR 153.A OH no hydrogen 3.393 N/A ASP 178.A N GLY 278.A O no hydrogen 2.587 N/A THR 180.A N ASP 178.A OD1 no hydrogen 3.434 N/A THR 180.A OG1 ASP 178.A OD1 no hydrogen 3.160 N/A THR 180.A OG1 ASP 178.A OD2 no hydrogen 3.414 N/A PHE 182.A N THR 179.A O no hydrogen 3.121 N/A MET 183.A N THR 180.A O no hydrogen 3.058 N/A TYR 184.A N THR 180.A O no hydrogen 3.427 N/A TYR 184.A OH SER 412.A OG no hydrogen 3.112 N/A MET 187.A N SER 323.A O no hydrogen 3.407 N/A GLY 189.A N TRP 198.A O no hydrogen 2.932 N/A TYR 191.A N THR 196.A O no hydrogen 2.887 N/A TYR 191.A OH ASP 178.A O no hydrogen 2.920 N/A TYR 194.A N TYR 191.A O no hydrogen 2.943 N/A TYR 194.A OH CYS 276.A O no hydrogen 2.822 N/A THR 196.A OG1 TYR 194.A O no hydrogen 3.232 N/A ASN 197.A N SER 236.A O no hydrogen 2.955 N/A TRP 198.A N GLY 189.A O no hydrogen 2.919 N/A ALA 199.A N LEU 234.A O no hydrogen 2.943 N/A ASP 200.A N MET 187.A O no hydrogen 3.048 N/A GLN 202.A N ASP 200.A OD2 no hydrogen 3.276 N/A GLN 202.A NE2 ASP 200.A OD2 no hydrogen 2.814 N/A GLN 202.A NE2 GLU 228.A O no hydrogen 2.609 N/A VAL 203.A N ASP 200.A O no hydrogen 3.350 N/A ALA 206.A N VAL 203.A O no hydrogen 3.298 N/A ASN 208.A N ASP 313.A OD2 no hydrogen 3.268 N/A CYS 212.A SG ILE 209.A O no hydrogen 3.150 N/A SER 213.A N LEU 204.A O no hydrogen 3.261 N/A SER 213.A OG CYS 212.A O no hydrogen 2.743 N/A ASP 215.A N THR 214.A OG1 no hydrogen 2.716 N/A ARG 220.A NE GLY 222.A O no hydrogen 2.695 N/A ARG 220.A NH2 GLY 222.A O no hydrogen 2.850 N/A CYS 230.A N.A ASP 200.A OD1 no hydrogen 3.374 N/A CYS 230.A N.B ASP 200.A OD1 no hydrogen 3.378 N/A CYS 230.A SG.A ASP 200.A OD1 no hydrogen 3.366 N/A CYS 230.A SG.A ASP 200.A OD2 no hydrogen 3.643 N/A CYS 230.A SG.A ARG 232.A O no hydrogen 3.735 N/A CYS 230.A SG.B GLU 228.A O no hydrogen 3.797 N/A VAL 233.A N GLU 244.A O no hydrogen 2.932 N/A LEU 234.A N ALA 199.A O no hydrogen 2.915 N/A PHE 235.A N TYR 242.A O no hydrogen 2.882 N/A SER 236.A N ASN 197.A O no hydrogen 2.864 N/A VAL 237.A N THR 240.A O no hydrogen 2.909 N/A GLY 238.A N SER 195.A O no hydrogen 2.879 N/A THR 240.A N VAL 237.A O no hydrogen 2.912 N/A TYR 242.A N PHE 235.A O no hydrogen 2.907 N/A GLU 244.A N VAL 233.A O no hydrogen 2.903 N/A SER 245.A OG ASP 231.A OD1 no hydrogen 2.392 N/A SER 245.A OG ASP 231.A OD2 no hydrogen 3.126 N/A ARG 246.A N ASP 231.A O no hydrogen 3.021 N/A ARG 246.A N ASP 231.A OD1 no hydrogen 2.799 N/A ARG 246.A NE CYS 230.A O.A no hydrogen 2.848 N/A ARG 246.A NE CYS 230.A O.B no hydrogen 2.841 N/A ARG 246.A NH1 ALA 186.A O no hydrogen 2.985 N/A ARG 246.A NH2 ALA 186.A O no hydrogen 2.947 N/A ARG 246.A NH2 ASP 200.A OD1 no hydrogen 3.561 N/A LEU 249.A N SER 245.A O no hydrogen 3.351 N/A LYS 250.A N ARG 246.A O no hydrogen 2.909 N/A SER 251.A N LYS 247.A O no hydrogen 2.921 N/A SER 251.A OG LEU 248.A O no hydrogen 3.092 N/A TRP 252.A N LEU 249.A O no hydrogen 3.470 N/A HIS 253.A N LYS 250.A O no hydrogen 3.103 N/A PHE 258.A N CYS 268.A O no hydrogen 2.934 N/A HIS 259.A N ALA 418.A O no hydrogen 3.278 N/A HIS 259.A NE2 GLY 292.A O no hydrogen 3.050 N/A LEU 260.A N PHE 266.A O no hydrogen 2.920 N/A LYS 261.A N PHE 420.A O no hydrogen 3.066 N/A GLY 262.A N LEU 264.A O no hydrogen 3.412 N/A PHE 266.A N LEU 260.A O no hydrogen 2.884 N/A THR 267.A N SER 287.A O no hydrogen 2.793 N/A THR 267.A OG1 HIS 259.A ND1 no hydrogen 2.997 N/A THR 267.A OG1 GLY 289.A O no hydrogen 2.801 N/A CYS 268.A N PHE 258.A O no hydrogen 2.890 N/A ARG 269.A N THR 285.A O no hydrogen 3.160 N/A CYS 270.A N SER 256.A O no hydrogen 3.203 N/A ASP 271.A N ARG 283.A O no hydrogen 3.154 N/A VAL 273.A N VAL 281.A O no hydrogen 3.109 N/A CYS 276.A N TYR 279.A O no hydrogen 2.879 N/A CYS 276.A SG GLU 277.A OE1 no hydrogen 3.671 N/A TYR 279.A N CYS 276.A O no hydrogen 2.943 N/A VAL 280.A N GLY 176.A O no hydrogen 2.865 N/A VAL 281.A N VAL 274.A O no hydrogen 2.919 N/A LYS 282.A N TRP 174.A O no hydrogen 2.841 N/A LYS 282.A NZ TRP 252.A O no hydrogen 2.917 N/A ARG 283.A N ASP 271.A O no hydrogen 2.925 N/A ILE 284.A N ALA 172.A O no hydrogen 2.900 N/A THR 285.A N ARG 269.A O no hydrogen 3.272 N/A MET 286.A N ARG 170.A O no hydrogen 3.440 N/A SER 287.A N THR 267.A O no hydrogen 3.227 N/A GLY 289.A N SER 265.A O no hydrogen 2.904 N/A TYR 291.A N THR 267.A OG1 no hydrogen 3.253 N/A THR 294.A OG1 GLU 419.A OE2 no hydrogen 3.432 N/A ALA 298.A N GLN 414.A O no hydrogen 2.891 N/A THR 300.A N SER 412.A O no hydrogen 2.894 N/A HIS 302.A N THR 410.A O no hydrogen 2.937 N/A HIS 302.A NE2 SER 412.A OG no hydrogen 2.847 N/A GLY 305.A N VAL 328.A O no hydrogen 2.924 N/A PHE 306.A N LYS 406.A O no hydrogen 2.922 N/A LEU 307.A N THR 326.A O no hydrogen 2.942 N/A MET 308.A N VAL 404.A O no hydrogen 2.937 N/A CYS 309.A N VAL 324.A O no hydrogen 2.904 N/A CYS 309.A SG VAL 324.A O no hydrogen 3.750 N/A LYS 310.A N HIS 402.A O no hydrogen 3.189 N/A THR 311.A N PHE 322.A O no hydrogen 2.871 N/A THR 312.A OG1 SER 321.A OG no hydrogen 2.997 N/A ASP 313.A N VAL 320.A O no hydrogen 2.902 N/A THR 314.A N ASP 313.A OD1 no hydrogen 2.918 N/A VAL 315.A N GLU 318.A O no hydrogen 2.870 N/A ASP 316.A N LYS 205.A O no hydrogen 3.200 N/A GLU 318.A N VAL 315.A O no hydrogen 2.929 N/A VAL 320.A N ASP 313.A O no hydrogen 2.915 N/A SER 321.A OG THR 311.A O no hydrogen 3.535 N/A SER 321.A OG THR 312.A OG1 no hydrogen 2.997 N/A PHE 322.A N THR 311.A O no hydrogen 2.944 N/A VAL 324.A N CYS 309.A O no hydrogen 2.915 N/A CYS 325.A N ALA 188.A O no hydrogen 3.381 N/A CYS 325.A SG ALA 188.A O no hydrogen 3.926 N/A THR 326.A N LEU 307.A O no hydrogen 2.904 N/A TYR 327.A OH ASP 178.A OD2 no hydrogen 3.257 N/A VAL 328.A N GLY 305.A O no hydrogen 2.877 N/A CYS 333.A N PRO 329.A O no hydrogen 3.416 N/A CYS 333.A SG PRO 329.A O no hydrogen 3.506 N/A CYS 333.A SG TYR 405.A OH no hydrogen 3.214 N/A ASP 334.A N ALA 330.A O no hydrogen 2.897 N/A GLN 335.A N THR 331.A O no hydrogen 2.927 N/A MET 336.A N CYS 333.A O no hydrogen 3.362 N/A THR 337.A N ASP 334.A O no hydrogen 3.464 N/A THR 337.A OG1 CYS 333.A O no hydrogen 3.463 N/A THR 337.A OG1 ASP 334.A O no hydrogen 2.980 N/A LEU 340.A N MET 336.A O no hydrogen 3.421 N/A ALA 341.A N GLY 338.A O no hydrogen 3.371 N/A THR 342.A N ILE 339.A O no hydrogen 3.445 N/A GLU 343.A N THR 342.A OG1 no hydrogen 2.758 N/A THR 345.A OG1 ASP 348.A OD2 no hydrogen 2.809 N/A GLU 347.A N GLU 347.A OE2 no hydrogen 2.484 N/A ALA 349.A N THR 345.A O no hydrogen 3.155 N/A GLN 350.A N PRO 346.A O no hydrogen 2.894 N/A LYS 351.A N GLU 347.A O no hydrogen 2.922 N/A LEU 352.A N ASP 348.A O no hydrogen 2.936 N/A LEU 353.A N ALA 349.A O no hydrogen 2.868 N/A VAL 354.A N GLN 350.A O no hydrogen 2.918 N/A GLY 355.A N LYS 351.A O no hydrogen 2.911 N/A LEU 356.A N LEU 352.A O no hydrogen 2.919 N/A ASN 357.A N LEU 353.A O no hydrogen 2.885 N/A ASN 357.A ND2 MET 360.A O no hydrogen 2.993 N/A THR 359.A N ASN 357.A OD1 no hydrogen 2.946 N/A MET 360.A N ASN 357.A OD1 no hydrogen 3.005 N/A LYS 361.A NZ PRO 192.A O no hydrogen 2.968 N/A TYR 363.A OH ASN 197.A OD1 no hydrogen 3.397 N/A VAL 368.A N MET 364.A O no hydrogen 3.324 N/A ALA 369.A N ILE 365.A O no hydrogen 2.961 N/A GLN 370.A N PRO 366.A O no hydrogen 3.427 N/A ALA 371.A N VAL 367.A O no hydrogen 2.944 N/A PHE 372.A N VAL 368.A O no hydrogen 2.946 N/A SER 373.A N ALA 369.A O no hydrogen 2.945 N/A SER 373.A OG VAL 344.A O no hydrogen 3.114 N/A LYS 374.A N GLN 370.A O no hydrogen 2.949 N/A TRP 375.A N ALA 371.A O no hydrogen 2.929 N/A ALA 376.A N PHE 372.A O no hydrogen 2.988 N/A GLU 378.A N LYS 374.A O no hydrogen 3.353 N/A CYS 379.A N TRP 375.A O no hydrogen 3.027 N/A CYS 379.A SG TRP 375.A O no hydrogen 3.714 N/A ARG 380.A N ALA 376.A O no hydrogen 3.347 N/A LYS 381.A N LYS 377.A O no hydrogen 2.943 N/A ASP 382.A N GLU 378.A O no hydrogen 2.923 N/A MET 383.A N CYS 379.A O no hydrogen 2.961 N/A GLU 384.A N ARG 380.A O no hydrogen 3.207 N/A ASP 385.A N ASP 382.A O no hydrogen 3.501 N/A LYS 387.A NZ ASP 385.A O no hydrogen 2.998 N/A LYS 387.A NZ ASP 385.A OD2 no hydrogen 2.609 N/A LYS 397.A NZ LYS 398.A O no hydrogen 3.325 N/A HIS 402.A N GLU 378.A OE2 no hydrogen 3.040 N/A VAL 404.A N MET 308.A O no hydrogen 2.873 N/A LYS 406.A N PHE 306.A O no hydrogen 2.887 N/A LYS 406.A NZ GLN 411.A O no hydrogen 3.381 N/A ASP 409.A N HIS 302.A O no hydrogen 2.794 N/A THR 410.A OG1 ARG 407.A O no hydrogen 2.433 N/A GLN 411.A NE2 HIS 301.A ND1 no hydrogen 3.172 N/A SER 412.A N THR 300.A O no hydrogen 2.884 N/A SER 412.A OG TYR 184.A OH no hydrogen 3.112 N/A SER 412.A OG HIS 302.A NE2 no hydrogen 2.847 N/A GLN 414.A N ALA 298.A O no hydrogen 2.932 N/A VAL 416.A N GLY 296.A O no hydrogen 3.011 N/A GLN 417.A NE2 GLU 419.A O no hydrogen 3.118 N/A PHE 420.A N HIS 259.A O no hydrogen 3.250 N/A