Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x1y_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 7.A NZ SER 19.A O no hydrogen 2.689 N/A LYS 7.A NZ HIS 20.A O no hydrogen 3.171 N/A LYS 7.A NZ THR 215.A OG1 no hydrogen 3.101 N/A MET 8.A N LEU 23.A O no hydrogen 2.641 N/A THR 10.A OG1 ASP 16.A OD1 no hydrogen 2.951 N/A PHE 15.A N ILE 12.A O no hydrogen 3.336 N/A ILE 18.A N PHE 15.A O no hydrogen 3.122 N/A SER 19.A N PHE 15.A O no hydrogen 3.201 N/A SER 19.A OG GLY 22.A O no hydrogen 2.542 N/A HIS 20.A ND1 SER 216.A O no hydrogen 3.297 N/A GLY 21.A N ASP 16.A O no hydrogen 2.999 N/A GLY 22.A N SER 19.A OG no hydrogen 2.946 N/A LEU 23.A N MET 8.A O no hydrogen 2.966 N/A ILE 25.A N ALA 6.A O no hydrogen 3.245 N/A LEU 30.A N ASN 190.A O no hydrogen 2.803 N/A VAL 31.A N MET 167.A O no hydrogen 2.768 N/A SER 32.A N VAL 192.A O no hydrogen 3.077 N/A SER 32.A OG ILE 178.A O no hydrogen 3.136 N/A GLY 33.A N THR 169.A O no hydrogen 3.150 N/A SER 35.A N THR 34.A OG1 no hydrogen 2.546 N/A LYS 39.A NZ THR 34.A O no hydrogen 3.076 N/A SER 43.A OG THR 40.A O no hydrogen 2.741 N/A ILE 44.A N THR 40.A O no hydrogen 3.384 N/A GLN 45.A N LEU 41.A O no hydrogen 2.871 N/A PHE 46.A N PHE 42.A O no hydrogen 2.917 N/A LEU 47.A N SER 43.A O no hydrogen 2.964 N/A TYR 48.A N ILE 44.A O no hydrogen 2.897 N/A ASN 49.A N GLN 45.A O no hydrogen 2.952 N/A ASN 49.A ND2 MET 11.A O no hydrogen 2.938 N/A ILE 51.A N LEU 47.A O no hydrogen 2.979 N/A ILE 52.A N TYR 48.A O no hydrogen 2.924 N/A GLU 53.A N ASN 49.A O no hydrogen 3.041 N/A GLU 56.A N GLY 50.A O no hydrogen 3.060 N/A VAL 59.A N ARG 128.A O no hydrogen 3.085 N/A PHE 60.A N PHE 91.A O no hydrogen 3.124 N/A VAL 61.A N SER 130.A O no hydrogen 3.212 N/A THR 62.A N LEU 93.A O no hydrogen 3.050 N/A THR 62.A OG1 LEU 93.A O no hydrogen 2.941 N/A THR 66.A OG1 ASP 69.A OD2 no hydrogen 2.303 N/A ILE 70.A N THR 66.A O no hydrogen 3.312 N/A ILE 71.A N PRO 67.A O no hydrogen 2.951 N/A LYS 72.A N GLN 68.A O no hydrogen 2.926 N/A ASN 73.A N ASP 69.A O no hydrogen 2.876 N/A ALA 74.A N ILE 70.A O no hydrogen 2.925 N/A ARG 75.A N ILE 71.A O no hydrogen 2.925 N/A SER 76.A N ASN 73.A O no hydrogen 3.442 N/A SER 76.A OG ASN 73.A O no hydrogen 3.240 N/A PHE 77.A N ALA 74.A O no hydrogen 3.360 N/A GLY 78.A N ARG 75.A O no hydrogen 3.378 N/A ALA 82.A N ASP 80.A OD1 no hydrogen 3.120 N/A LYS 83.A N ASP 80.A OD2 no hydrogen 3.353 N/A LYS 83.A NZ GLU 87.A OE2 no hydrogen 3.155 N/A VAL 85.A N LEU 81.A O no hydrogen 2.939 N/A ASP 86.A N ALA 82.A O no hydrogen 2.929 N/A GLU 87.A N LYS 83.A O no hydrogen 2.962 N/A GLY 88.A N VAL 85.A O no hydrogen 3.126 N/A LYS 89.A N LEU 84.A O no hydrogen 3.067 N/A LYS 89.A NZ ASP 55.A OD1 no hydrogen 2.771 N/A LEU 90.A N LEU 84.A O no hydrogen 3.348 N/A PHE 91.A N GLY 58.A O no hydrogen 3.395 N/A LEU 93.A N PHE 60.A O no hydrogen 2.597 N/A ALA 95.A N THR 62.A O no hydrogen 3.046 N/A SER 96.A OG ASP 94.A OD1 no hydrogen 3.222 N/A SER 96.A OG ASP 94.A OD2 no hydrogen 3.236 N/A GLU 100.A N ASP 98.A OD1 no hydrogen 3.038 N/A ILE 114.A N ASP 109.A O no hydrogen 2.672 N/A ARG 116.A N ALA 112.A O no hydrogen 2.913 N/A ARG 116.A NH1 ASP 94.A O no hydrogen 3.070 N/A ASN 118.A N ILE 114.A O no hydrogen 2.894 N/A TYR 119.A N GLU 115.A O no hydrogen 2.892 N/A ALA 120.A N ARG 116.A O no hydrogen 2.944 N/A ILE 121.A N ILE 117.A O no hydrogen 2.895 N/A GLN 122.A N ASN 118.A O no hydrogen 2.999 N/A GLN 122.A NE2 ASN 118.A OD1 no hydrogen 3.155 N/A LYS 123.A N ALA 120.A O no hydrogen 3.226 N/A TYR 124.A N ALA 120.A O no hydrogen 2.909 N/A ARG 125.A NH2 LYS 123.A O no hydrogen 3.401 N/A ARG 127.A N PRO 57.A O no hydrogen 2.844 N/A ARG 128.A NH1 PHE 46.A O no hydrogen 2.815 N/A ARG 128.A NH2 ARG 9.A O no hydrogen 2.853 N/A VAL 129.A N THR 164.A O no hydrogen 2.842 N/A SER 130.A N VAL 59.A O no hydrogen 3.317 N/A ASP 132.A N VAL 61.A O no hydrogen 3.304 N/A SER 133.A OG GLU 64.A OE2 no hydrogen 3.266 N/A SER 133.A OG ASP 132.A O no hydrogen 2.556 N/A VAL 134.A N THR 168.A O no hydrogen 3.113 N/A SER 136.A N SER 133.A O no hydrogen 3.203 N/A SER 136.A OG SER 133.A O no hydrogen 3.491 N/A VAL 137.A N VAL 134.A O no hydrogen 3.404 N/A GLN 140.A N GLN 140.A OE1 no hydrogen 2.574 N/A VAL 146.A N ALA 143.A O no hydrogen 2.482 N/A VAL 147.A N ALA 143.A O no hydrogen 3.383 N/A LEU 151.A N VAL 147.A O no hydrogen 2.960 N/A PHE 152.A N ARG 148.A O no hydrogen 2.889 N/A ARG 153.A N ARG 149.A O no hydrogen 2.917 N/A ARG 153.A NE ARG 149.A O no hydrogen 2.949 N/A LEU 154.A N GLU 150.A O no hydrogen 3.030 N/A VAL 155.A N LEU 151.A O no hydrogen 2.940 N/A ALA 156.A N PHE 152.A O no hydrogen 2.911 N/A ARG 157.A N ARG 153.A O no hydrogen 2.918 N/A LEU 158.A N LEU 154.A O no hydrogen 2.983 N/A LYS 159.A N VAL 155.A O no hydrogen 2.915 N/A LYS 159.A NZ ASP 189.A OD2 no hydrogen 3.500 N/A GLN 160.A N ALA 156.A O no hydrogen 2.928 N/A ILE 161.A N ARG 157.A O no hydrogen 2.958 N/A GLY 162.A N LEU 158.A O no hydrogen 3.064 N/A THR 164.A N ARG 127.A O no hydrogen 3.337 N/A THR 165.A OG1 ALA 163.A O no hydrogen 3.246 N/A VAL 166.A N VAL 129.A O no hydrogen 3.039 N/A MET 167.A N THR 29.A O no hydrogen 2.704 N/A THR 168.A OG1 ASP 132.A OD1 no hydrogen 3.272 N/A THR 169.A N VAL 31.A O no hydrogen 3.283 N/A ARG 171.A N GLY 33.A O no hydrogen 3.173 N/A ARG 171.A NE PRO 177.A O no hydrogen 3.400 N/A ARG 171.A NH2 GLU 174.A O no hydrogen 2.729 N/A ARG 171.A NH2 PRO 177.A O no hydrogen 3.417 N/A VAL 183.A N GLU 184.A OE1 no hydrogen 3.363 N/A GLU 184.A N GLU 184.A OE1 no hydrogen 2.628 N/A GLU 185.A N GLU 185.A OE2 no hydrogen 2.489 N/A PHE 186.A N VAL 183.A O no hydrogen 2.951 N/A VAL 187.A N GLU 184.A O no hydrogen 3.390 N/A SER 188.A N GLU 184.A O no hydrogen 3.250 N/A ASN 190.A ND2 THR 29.A OG1 no hydrogen 3.092 N/A VAL 191.A N LYS 211.A O no hydrogen 3.194 N/A VAL 192.A N LEU 30.A O no hydrogen 2.679 N/A ILE 193.A N GLU 208.A O no hydrogen 2.935 N/A LEU 194.A N SER 32.A O no hydrogen 3.137 N/A ARG 195.A N THR 206.A O no hydrogen 3.132 N/A ASN 196.A N GLU 174.A OE1 no hydrogen 3.341 N/A ASN 196.A N GLU 174.A OE2 no hydrogen 3.404 N/A GLU 199.A N ARG 202.A O no hydrogen 2.994 N/A ARG 202.A N GLU 199.A O no hydrogen 3.300 N/A ARG 202.A NE GLU 201.A O no hydrogen 2.398 N/A ARG 203.A NH1 ASN 196.A O no hydrogen 2.721 N/A ARG 204.A N VAL 197.A O no hydrogen 3.222 N/A ARG 204.A NH2 GLN 381.A OE1 no hydrogen 2.915 N/A ARG 205.A NH1 GLY 36.A O no hydrogen 3.262 N/A THR 206.A N ARG 195.A O no hydrogen 3.223 N/A THR 206.A OG1 GLU 221.A OE1 no hydrogen 2.512 N/A LEU 207.A N TYR 222.A O no hydrogen 2.620 N/A GLU 208.A N ILE 193.A O no hydrogen 3.161 N/A LEU 210.A N VAL 191.A O no hydrogen 2.827 N/A LYS 211.A NZ GLU 185.A O no hydrogen 3.189 N/A ARG 213.A NH1 ASP 189.A OD1 no hydrogen 2.776 N/A SER 216.A N THR 215.A OG1 no hydrogen 2.751 N/A HIS 217.A ND1 MET 218.A O no hydrogen 3.253 N/A MET 218.A N ILE 18.A O no hydrogen 3.154 N/A TYR 222.A N LEU 207.A O no hydrogen 2.653 N/A PHE 224.A N ARG 205.A O no hydrogen 3.239 N/A THR 225.A N ASN 232.A O no hydrogen 3.290 N/A THR 227.A N GLY 230.A O no hydrogen 3.088 N/A THR 227.A OG1 GLY 230.A O no hydrogen 3.054 N/A GLY 230.A N THR 227.A O no hydrogen 3.324 N/A ILE 231.A N GLN 45.A OE1 no hydrogen 3.226 N/A ASN 232.A N THR 225.A O no hydrogen 3.052 N/A ASN 232.A ND2 GLN 348.A OE1 no hydrogen 3.221 N/A ILE 233.A N GLU 13.A O no hydrogen 3.044 N/A PHE 234.A N PRO 223.A O no hydrogen 3.210 N/A THR 242.A OG1 GLU 394.A OE2 no hydrogen 2.611 N/A SER 245.A N GLN 243.A O no hydrogen 2.720 N/A SER 245.A OG ASP 268.A OD1 no hydrogen 3.104 N/A SER 246.A N SER 245.A OG no hydrogen 2.741 N/A SER 246.A OG SER 245.A O no hydrogen 2.788 N/A ARG 249.A NH1 SER 435.A OG no hydrogen 2.405 N/A ARG 249.A NH2 GLY 264.A O no hydrogen 3.063 N/A VAL 250.A N PHE 265.A O no hydrogen 2.656 N/A SER 251.A OG ASN 291.A OD1 no hydrogen 2.308 N/A SER 252.A N ASP 258.A OD2 no hydrogen 3.160 N/A SER 252.A OG VAL 254.A O no hydrogen 3.444 N/A SER 252.A OG ASP 258.A OD1 no hydrogen 2.457 N/A GLY 253.A N ASN 291.A OD1 no hydrogen 3.141 N/A VAL 254.A N SER 252.A O no hydrogen 2.783 N/A ARG 256.A NE ILE 453.A O no hydrogen 3.519 N/A ASP 258.A N VAL 255.A O no hydrogen 2.586 N/A GLU 259.A N VAL 255.A O no hydrogen 3.015 N/A GLU 259.A N GLU 259.A OE1 no hydrogen 2.964 N/A CYS 261.A SG CYS 261.A O no hydrogen 3.012 N/A LYS 267.A NZ GLU 394.A O no hydrogen 3.124 N/A SER 269.A OG PHE 266.A O no hydrogen 2.584 N/A ILE 271.A N GLY 397.A O no hydrogen 2.874 N/A LEU 272.A N THR 410.A O no hydrogen 2.980 N/A ALA 273.A N PHE 399.A O no hydrogen 3.009 N/A THR 274.A N ILE 412.A O no hydrogen 3.012 N/A THR 279.A OG1 ALA 276.A O no hydrogen 2.857 N/A THR 279.A OG1 THR 277.A O no hydrogen 3.290 N/A VAL 285.A N LYS 281.A O no hydrogen 3.003 N/A SER 286.A N THR 282.A O no hydrogen 2.864 N/A ARG 287.A N LEU 283.A O no hydrogen 2.938 N/A PHE 288.A N LEU 284.A O no hydrogen 2.929 N/A VAL 289.A N VAL 285.A O no hydrogen 2.948 N/A GLU 290.A N SER 286.A O no hydrogen 2.897 N/A ASN 291.A N ARG 287.A O no hydrogen 2.949 N/A ASN 291.A ND2 ASN 291.A O no hydrogen 2.563 N/A ALA 292.A N VAL 289.A O no hydrogen 3.081 N/A CYS 293.A SG GLU 290.A O no hydrogen 3.142 N/A ALA 294.A N ASN 291.A O no hydrogen 3.132 N/A LYS 296.A N CYS 293.A O no hydrogen 3.158 N/A GLU 297.A N ALA 292.A O no hydrogen 3.103 N/A ILE 300.A N ARG 361.A O no hydrogen 3.101 N/A LEU 301.A N LYS 332.A O no hydrogen 3.001 N/A PHE 302.A N ALA 363.A O no hydrogen 3.029 N/A ARG 308.A NH2 GLU 326.A OE1 no hydrogen 3.438 N/A ARG 308.A NH2 GLU 326.A OE2 no hydrogen 2.847 N/A GLN 310.A N SER 307.A O no hydrogen 3.430 N/A LEU 312.A N ARG 308.A O no hydrogen 2.754 N/A ARG 313.A N ALA 309.A O no hydrogen 2.910 N/A ARG 313.A NH2 ASN 314.A OD1 no hydrogen 3.260 N/A ASN 314.A N GLN 310.A O no hydrogen 2.937 N/A ASN 314.A ND2 GLU 306.A OE1 no hydrogen 3.330 N/A ALA 315.A N LEU 311.A O no hydrogen 2.899 N/A TYR 316.A N LEU 312.A O no hydrogen 2.906 N/A SER 317.A N ARG 313.A O no hydrogen 2.913 N/A TRP 318.A N ASN 314.A O no hydrogen 2.962 N/A GLY 319.A N TYR 316.A O no hydrogen 3.363 N/A MET 320.A N ALA 315.A O no hydrogen 2.870 N/A GLU 324.A N ASP 321.A O no hydrogen 3.266 N/A GLU 326.A N PHE 322.A O no hydrogen 2.907 N/A ARG 327.A N GLU 323.A O no hydrogen 2.898 N/A ASN 329.A N GLU 326.A O no hydrogen 3.196 N/A LEU 330.A N MET 325.A O no hydrogen 3.236 N/A LYS 332.A N ALA 299.A O no hydrogen 3.202 N/A LYS 332.A NZ GLU 353.A OE1 no hydrogen 2.394 N/A VAL 334.A N LEU 301.A O no hydrogen 3.370 N/A CYS 335.A SG GLU 306.A O no hydrogen 3.978 N/A ALA 336.A N ALA 303.A O no hydrogen 3.241 N/A SER 340.A N TYR 337.A O no hydrogen 3.367 N/A SER 340.A OG TYR 337.A O no hydrogen 3.241 N/A GLU 344.A N GLU 344.A OE2 no hydrogen 2.783 N/A HIS 346.A N GLY 342.A O no hydrogen 2.995 N/A HIS 346.A NE2 PRO 338.A O no hydrogen 3.075 N/A LEU 347.A N LEU 343.A O no hydrogen 2.934 N/A GLN 348.A N GLU 344.A O no hydrogen 2.920 N/A ILE 349.A N ASP 345.A O no hydrogen 2.930 N/A ILE 350.A N HIS 346.A O no hydrogen 2.935 N/A LYS 351.A N LEU 347.A O no hydrogen 2.950 N/A SER 352.A N GLN 348.A O no hydrogen 2.917 N/A SER 352.A OG GLN 348.A O no hydrogen 3.306 N/A SER 352.A OG ILE 349.A O no hydrogen 2.745 N/A GLU 353.A N ILE 349.A O no hydrogen 2.947 N/A ILE 354.A N ILE 350.A O no hydrogen 2.956 N/A ASN 355.A N LYS 351.A O no hydrogen 2.941 N/A ASP 356.A N SER 352.A O no hydrogen 2.879 N/A PHE 357.A N GLU 353.A O no hydrogen 2.950 N/A LYS 358.A N ILE 354.A O no hydrogen 3.111 N/A ALA 360.A N ARG 298.A O no hydrogen 2.937 N/A ILE 362.A N THR 396.A O no hydrogen 3.005 N/A ALA 363.A N ILE 300.A O no hydrogen 3.137 N/A ILE 364.A N LEU 398.A O no hydrogen 3.003 N/A ASP 365.A N PHE 302.A O no hydrogen 2.948 N/A SER 366.A OG GLU 305.A OE2 no hydrogen 1.675 N/A SER 366.A OG ASP 365.A OD1 no hydrogen 2.700 N/A LEU 367.A N THR 400.A O no hydrogen 2.691 N/A ALA 369.A N SER 366.A O no hydrogen 3.087 N/A LEU 370.A N LEU 367.A O no hydrogen 3.062 N/A PHE 379.A N SER 375.A O no hydrogen 3.348 N/A ARG 380.A N ASN 376.A O no hydrogen 2.946 N/A GLN 381.A N ASN 377.A O no hydrogen 2.954 N/A PHE 382.A N ALA 378.A O no hydrogen 2.939 N/A VAL 383.A N PHE 379.A O no hydrogen 2.945 N/A ILE 384.A N ARG 380.A O no hydrogen 3.007 N/A GLY 385.A N GLN 381.A O no hydrogen 2.934 N/A VAL 386.A N PHE 382.A O no hydrogen 2.964 N/A THR 387.A N VAL 383.A O no hydrogen 2.980 N/A THR 387.A OG1 VAL 383.A O no hydrogen 3.058 N/A GLY 388.A N ILE 384.A O no hydrogen 2.893 N/A TYR 389.A N GLY 385.A O no hydrogen 2.972 N/A TYR 389.A OH ASN 355.A OD1 no hydrogen 2.407 N/A ALA 390.A N VAL 386.A O no hydrogen 2.942 N/A LYS 391.A N THR 387.A O no hydrogen 2.907 N/A LYS 391.A NZ ASP 409.A OD1 no hydrogen 3.447 N/A LYS 391.A NZ ASP 409.A OD2 no hydrogen 3.364 N/A GLN 392.A N GLY 388.A O no hydrogen 2.929 N/A GLU 393.A N TYR 389.A O no hydrogen 3.256 N/A ILE 395.A N ALA 390.A O no hydrogen 3.184 N/A THR 396.A OG1 LYS 267.A O no hydrogen 2.248 N/A GLY 397.A N SER 269.A O no hydrogen 3.347 N/A LEU 398.A N ILE 362.A O no hydrogen 2.895 N/A PHE 399.A N ILE 271.A O no hydrogen 2.805 N/A ASN 401.A N ALA 273.A O no hydrogen 2.981 N/A SER 403.A N GLY 275.A O no hydrogen 2.659 N/A SER 403.A OG SER 403.A O no hydrogen 2.536 N/A ILE 407.A N ILE 404.A O no hydrogen 3.084 N/A THR 408.A N ILE 404.A O no hydrogen 3.140 N/A THR 408.A OG1 ILE 404.A O no hydrogen 3.541 N/A THR 408.A OG1 ALA 405.A O no hydrogen 3.332 N/A ASP 409.A N ILE 270.A O no hydrogen 2.971 N/A THR 410.A N ILE 270.A O no hydrogen 3.312 N/A ILE 411.A N LYS 431.A O no hydrogen 3.217 N/A ILE 412.A N LEU 272.A O no hydrogen 2.913 N/A LEU 413.A N ASN 428.A O no hydrogen 2.831 N/A LEU 414.A N THR 274.A O no hydrogen 2.965 N/A TYR 416.A OH THR 277.A O no hydrogen 2.286 N/A VAL 417.A N SER 424.A O no hydrogen 3.324 N/A ILE 419.A N GLU 422.A O no hydrogen 2.666 N/A GLU 422.A N ILE 419.A O no hydrogen 2.903 N/A SER 424.A N VAL 417.A O no hydrogen 2.886 N/A ARG 425.A NH2 GLY 278.A O no hydrogen 2.589 N/A ALA 426.A N GLN 415.A O no hydrogen 3.346 N/A ILE 427.A N ARG 442.A O no hydrogen 2.620 N/A PHE 430.A N ILE 411.A O no hydrogen 2.697 N/A LYS 431.A NZ ALA 405.A O no hydrogen 3.376 N/A LYS 431.A NZ THR 408.A O no hydrogen 3.363 N/A ARG 433.A NH1 ASP 409.A OD1 no hydrogen 2.924 N/A ARG 433.A NH2 ALA 406.A O no hydrogen 3.396 N/A SER 435.A OG GLY 434.A O no hydrogen 2.686 N/A ARG 442.A N ILE 427.A O no hydrogen 3.270 N/A ARG 442.A NH2 ASP 438.A OD2 no hydrogen 3.337 N/A MET 445.A N ASP 452.A OD1 no hydrogen 2.881 N/A SER 447.A N GLY 450.A O no hydrogen 3.292 N/A SER 447.A OG GLY 450.A O no hydrogen 2.746 N/A ASP 452.A N MET 445.A O no hydrogen 3.304 N/A LYS 454.A N GLU 443.A O no hydrogen 2.594 N/A