Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x3j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 7.A NH1 ASP 6.A O no hydrogen 2.717 N/A ARG 7.A NH1 LYS 528.A O no hydrogen 2.742 N/A ARG 7.A NH2 LYS 528.A O no hydrogen 3.114 N/A THR 9.A OG1 ASP 524.A O no hydrogen 2.726 N/A GLY 10.A N THR 9.A OG1 no hydrogen 2.719 N/A GLU 11.A N GLU 11.A OE1 no hydrogen 2.923 N/A ARG 14.A N GLU 11.A O no hydrogen 3.124 N/A ARG 14.A NE ASP 524.A OD1 no hydrogen 2.802 N/A SER 15.A N GLU 11.A O no hydrogen 3.043 N/A GLN 16.A N THR 12.A O no hydrogen 3.299 N/A ASN 17.A N ILE 13.A O no hydrogen 3.275 N/A VAL 18.A N ARG 14.A O no hydrogen 3.399 N/A MET 19.A N SER 15.A O no hydrogen 3.336 N/A ALA 20.A N GLN 16.A O no hydrogen 3.341 N/A ALA 21.A N ASN 17.A O no hydrogen 3.247 N/A ALA 22.A N VAL 18.A O no hydrogen 2.990 N/A SER 23.A OG MET 19.A O no hydrogen 3.136 N/A ILE 24.A N ALA 21.A O no hydrogen 3.312 N/A ASN 26.A N ALA 22.A O no hydrogen 3.290 N/A ILE 27.A N ILE 24.A O no hydrogen 3.157 N/A VAL 28.A N ALA 25.A O no hydrogen 3.095 N/A LEU 37.A N SER 30.A O no hydrogen 3.158 N/A LYS 39.A N THR 51.A O no hydrogen 3.194 N/A LEU 41.A N THR 49.A O no hydrogen 3.186 N/A ASP 43.A N ASP 47.A O no hydrogen 3.119 N/A THR 49.A N LEU 41.A O no hydrogen 3.348 N/A THR 51.A OG1 THR 56.A OG1 no hydrogen 3.288 N/A THR 56.A OG1 THR 51.A OG1 no hydrogen 3.288 N/A THR 56.A OG1 ASP 53.A O no hydrogen 3.087 N/A ILE 57.A N ASP 53.A O no hydrogen 3.240 N/A LEU 58.A N GLY 54.A O no hydrogen 3.451 N/A LEU 61.A N ILE 57.A O no hydrogen 2.925 N/A HIS 65.A N VAL 63.A O no hydrogen 2.932 N/A ALA 67.A N HIS 65.A ND1 no hydrogen 3.155 N/A LYS 69.A N HIS 65.A O no hydrogen 2.867 N/A LYS 69.A NZ GLU 64.A OE1 no hydrogen 3.336 N/A GLU 73.A N VAL 70.A O no hydrogen 3.392 N/A ASP 76.A N GLU 73.A O no hydrogen 3.061 N/A LEU 77.A N GLU 73.A O no hydrogen 3.245 N/A GLN 78.A NE2 ASP 84.A O no hydrogen 3.435 N/A ASP 79.A N ALA 75.A O no hydrogen 3.493 N/A VAL 82.A N GLN 78.A O no hydrogen 3.236 N/A GLY 83.A N GLN 78.A O no hydrogen 3.122 N/A SER 88.A N GLY 85.A O no hydrogen 2.974 N/A SER 88.A OG GLY 85.A O no hydrogen 2.342 N/A VAL 90.A N THR 87.A O no hydrogen 3.162 N/A ILE 91.A N THR 87.A O no hydrogen 3.259 N/A ALA 93.A N VAL 89.A O no hydrogen 3.061 N/A ALA 94.A N VAL 90.A O no hydrogen 3.047 N/A GLU 95.A N ILE 91.A O no hydrogen 3.249 N/A LEU 96.A N ILE 92.A O no hydrogen 2.862 N/A LEU 97.A N ALA 93.A O no hydrogen 3.057 N/A LYS 98.A N ALA 94.A O no hydrogen 3.022 N/A LYS 98.A NZ GLU 95.A OE2 no hydrogen 3.136 N/A ASN 99.A N GLU 95.A O no hydrogen 3.188 N/A ALA 100.A N LEU 96.A O no hydrogen 3.170 N/A ASP 101.A N LEU 97.A O no hydrogen 2.892 N/A LEU 103.A N ALA 100.A O no hydrogen 3.105 N/A VAL 104.A N ALA 100.A O no hydrogen 3.226 N/A LYS 105.A NZ ASP 101.A OD1 no hydrogen 3.541 N/A LYS 105.A NZ ASP 101.A OD2 no hydrogen 3.511 N/A GLN 106.A N LEU 103.A O no hydrogen 3.178 N/A ILE 108.A N LEU 103.A O no hydrogen 3.187 N/A HIS 109.A ND1 THR 111.A OG1 no hydrogen 2.749 N/A THR 111.A N HIS 109.A ND1 no hydrogen 3.452 N/A THR 111.A OG1 HIS 109.A ND1 no hydrogen 2.749 N/A SER 112.A OG HIS 109.A O no hydrogen 2.868 N/A ILE 114.A N PRO 110.A O no hydrogen 2.857 N/A SER 115.A N THR 111.A O no hydrogen 3.192 N/A SER 115.A OG GLU 430.A OE2 no hydrogen 2.572 N/A GLY 116.A N SER 112.A O no hydrogen 3.018 N/A TYR 117.A N VAL 113.A O no hydrogen 3.028 N/A TYR 117.A N ILE 114.A O no hydrogen 3.269 N/A TYR 117.A OH LEU 96.A O no hydrogen 3.244 N/A ARG 118.A N ILE 114.A O no hydrogen 3.364 N/A ALA 120.A N GLY 116.A O no hydrogen 3.124 N/A CYS 121.A N TYR 117.A O no hydrogen 2.893 N/A CYS 121.A SG LEU 510.A O no hydrogen 3.554 N/A LYS 122.A N ARG 118.A O no hydrogen 3.182 N/A GLU 123.A N LEU 119.A O no hydrogen 3.277 N/A ALA 124.A N ALA 120.A O no hydrogen 3.209 N/A ALA 124.A N CYS 121.A O no hydrogen 3.162 N/A VAL 125.A N CYS 121.A O no hydrogen 3.288 N/A ARG 126.A N LYS 122.A O no hydrogen 3.315 N/A TYR 127.A N GLU 123.A O no hydrogen 3.154 N/A ILE 128.A N ALA 124.A O no hydrogen 3.144 N/A ASN 129.A N VAL 125.A O no hydrogen 2.959 N/A GLU 130.A N ARG 126.A O no hydrogen 3.251 N/A ASN 131.A N ILE 128.A O no hydrogen 2.996 N/A ASN 131.A ND2 TYR 127.A O no hydrogen 2.733 N/A ILE 133.A N VAL 404.A O no hydrogen 3.351 N/A ASN 135.A ND2 LEU 399.A O no hydrogen 2.695 N/A ASP 137.A N THR 136.A OG1 no hydrogen 2.487 N/A ASN 146.A N ASP 142.A OD1 no hydrogen 3.020 N/A ASN 146.A N ASP 142.A OD2 no hydrogen 3.112 N/A ASN 146.A ND2 GLN 496.A O no hydrogen 2.485 N/A ALA 147.A N LEU 144.A O no hydrogen 2.149 N/A ALA 148.A N LEU 144.A O no hydrogen 2.895 N/A LYS 149.A N ILE 145.A O no hydrogen 3.234 N/A THR 150.A OG1 ASN 146.A O no hydrogen 3.297 N/A MET 152.A N ALA 148.A O no hydrogen 3.309 N/A SER 153.A N THR 150.A O no hydrogen 3.497 N/A SER 153.A OG THR 150.A O no hydrogen 3.233 N/A LYS 155.A NZ GLU 383.A OE2 no hydrogen 2.649 N/A GLY 158.A N LYS 155.A O no hydrogen 3.510 N/A ALA 165.A N GLY 161.A O no hydrogen 3.167 N/A MET 167.A N PHE 164.A O no hydrogen 3.362 N/A VAL 169.A N ALA 165.A O no hydrogen 3.231 N/A VAL 172.A N VAL 168.A O no hydrogen 3.155 N/A LEU 173.A N VAL 169.A O no hydrogen 3.265 N/A ILE 175.A N VAL 172.A O no hydrogen 3.420 N/A LYS 176.A NZ GLU 138.A OE1 no hydrogen 3.284 N/A GLN 183.A N ILE 180.A O no hydrogen 3.041 N/A VAL 191.A N SER 190.A OG no hydrogen 2.476 N/A ASN 192.A N ALA 369.A O no hydrogen 3.364 N/A ASN 192.A ND2 ALA 211.A O no hydrogen 3.640 N/A LEU 194.A N ILE 371.A O no hydrogen 3.144 N/A LYS 195.A NZ ASP 378.A OD1 no hydrogen 2.567 N/A ALA 196.A N LEU 373.A O no hydrogen 3.369 N/A GLN 201.A N GLN 201.A OE1 no hydrogen 3.011 N/A MET 202.A N SER 200.A OG no hydrogen 3.092 N/A SER 204.A OG ILE 372.A O no hydrogen 2.668 N/A LEU 212.A N ILE 358.A O no hydrogen 2.780 N/A ALA 231.A N VAL 281.A O no hydrogen 2.790 N/A CYS 232.A SG THR 322.A O no hydrogen 3.381 N/A CYS 232.A SG MET 340.A O no hydrogen 3.956 N/A ASP 234.A N LEU 324.A O no hydrogen 2.723 N/A GLN 238.A NE2 ILE 288.A O no hydrogen 3.295 N/A THR 240.A OG1 LYS 241.A O no hydrogen 3.487 N/A GLU 254.A N GLU 254.A OE2 no hydrogen 2.846 N/A LYS 255.A NZ VAL 249.A O no hydrogen 2.737 N/A ASP 257.A N GLU 254.A O no hydrogen 3.266 N/A ARG 260.A N ASP 257.A O no hydrogen 3.240 N/A GLN 261.A N ASP 257.A O no hydrogen 3.235 N/A GLN 261.A NE2 ASP 257.A O no hydrogen 3.178 N/A ARG 262.A N GLN 258.A O no hydrogen 3.058 N/A GLU 263.A N ILE 259.A O no hydrogen 3.161 N/A SER 264.A N ARG 260.A O no hydrogen 3.139 N/A SER 264.A OG GLN 261.A O no hydrogen 2.988 N/A ASP 265.A N GLN 261.A O no hydrogen 3.054 N/A ASP 265.A N ARG 262.A O no hydrogen 3.238 N/A ILE 266.A N ARG 262.A O no hydrogen 2.834 N/A THR 267.A OG1 GLU 263.A O no hydrogen 2.962 N/A THR 267.A OG1 SER 264.A O no hydrogen 2.915 N/A ARG 270.A N ILE 266.A O no hydrogen 3.379 N/A LYS 273.A N ARG 270.A O no hydrogen 3.307 N/A LYS 273.A NZ GLU 333.A O no hydrogen 2.448 N/A ILE 274.A N ARG 270.A O no hydrogen 3.324 N/A LEU 275.A N ILE 271.A O no hydrogen 3.408 N/A THR 277.A N ILE 274.A O no hydrogen 3.353 N/A THR 277.A OG1 ILE 274.A O no hydrogen 2.359 N/A GLY 278.A N LEU 275.A O no hydrogen 3.378 N/A ILE 282.A N MET 302.A O no hydrogen 2.991 N/A LEU 283.A N ALA 231.A O no hydrogen 3.436 N/A THR 284.A N VAL 304.A O no hydrogen 3.035 N/A THR 285.A OG1 ASP 234.A OD2 no hydrogen 3.380 N/A ASP 290.A N ASP 290.A OD1 no hydrogen 2.554 N/A MET 291.A N ASP 289.A OD2 no hydrogen 3.468 N/A LEU 293.A N ASP 289.A O no hydrogen 3.128 N/A TYR 295.A N CYS 292.A O no hydrogen 3.341 N/A PHE 296.A N LEU 293.A O no hydrogen 3.389 N/A ALA 299.A N TYR 295.A O no hydrogen 3.396 N/A GLY 300.A N PHE 296.A O no hydrogen 3.034 N/A ALA 301.A N PHE 296.A O no hydrogen 3.278 N/A VAL 304.A N ILE 282.A O no hydrogen 2.615 N/A VAL 307.A N THR 284.A O no hydrogen 3.367 N/A LEU 312.A N LEU 308.A O no hydrogen 3.219 N/A LEU 312.A N LYS 309.A O no hydrogen 3.204 N/A LYS 313.A N LYS 309.A O no hydrogen 3.208 N/A ARG 314.A NH2 ASP 311.A OD1 no hydrogen 2.945 N/A ILE 315.A N ASP 311.A O no hydrogen 3.235 N/A ALA 316.A N LEU 312.A O no hydrogen 2.976 N/A LYS 317.A N LYS 313.A O no hydrogen 3.367 N/A ALA 318.A N ILE 315.A O no hydrogen 3.026 N/A SER 319.A N ILE 315.A O no hydrogen 3.270 N/A THR 322.A OG1 ALA 339.A O no hydrogen 3.543 N/A GLU 334.A N LEU 327.A O no hydrogen 3.460 N/A GLU 337.A N GLU 337.A OE1 no hydrogen 2.843 N/A GLY 342.A N ILE 230.A O no hydrogen 3.397 N/A GLU 345.A N LYS 361.A O no hydrogen 3.243 N/A ILE 358.A N LEU 212.A O no hydrogen 3.070 N/A LEU 359.A N VAL 348.A O no hydrogen 3.501 N/A ILE 360.A N TYR 210.A O no hydrogen 3.132 N/A THR 363.A OG1 ALA 318.A O no hydrogen 3.324 N/A ALA 365.A N ALA 318.A O no hydrogen 2.997 N/A ARG 366.A NE SER 368.A O no hydrogen 2.935 N/A ARG 366.A NH1 ILE 360.A O no hydrogen 3.503 N/A THR 367.A OG1 ARG 366.A O no hydrogen 2.607 N/A SER 368.A OG SER 190.A O no hydrogen 3.509 N/A SER 368.A OG ALA 369.A O no hydrogen 3.365 N/A SER 370.A N ILE 207.A O no hydrogen 3.409 N/A SER 370.A OG GLY 209.A O no hydrogen 2.373 N/A ILE 371.A N ASN 192.A O no hydrogen 3.383 N/A LEU 373.A N LEU 194.A O no hydrogen 2.881 N/A ARG 374.A N ILE 372.A O no hydrogen 3.059 N/A ARG 374.A NE GLU 203.A O no hydrogen 2.684 N/A ARG 374.A NH2 GLU 203.A O no hydrogen 2.854 N/A GLY 375.A N ALA 196.A O no hydrogen 2.856 N/A MET 380.A N ASN 377.A OD1 no hydrogen 3.254 N/A CYS 381.A SG ALA 196.A O no hydrogen 3.855 N/A CYS 381.A SG LEU 373.A O no hydrogen 3.650 N/A CYS 381.A SG ASN 377.A O no hydrogen 3.290 N/A ASP 382.A N ASP 378.A O no hydrogen 3.299 N/A GLU 385.A N CYS 381.A O no hydrogen 3.216 N/A SER 387.A OG MET 384.A O no hydrogen 2.704 N/A LEU 388.A N MET 384.A O no hydrogen 3.079 N/A HIS 389.A N GLU 385.A O no hydrogen 3.112 N/A ASP 390.A N ARG 386.A O no hydrogen 3.022 N/A ALA 391.A N SER 387.A O no hydrogen 3.048 N/A LEU 392.A N LEU 388.A O no hydrogen 2.951 N/A CYS 393.A N HIS 389.A O no hydrogen 3.401 N/A CYS 393.A SG HIS 389.A O no hydrogen 3.991 N/A CYS 393.A SG ASP 390.A O no hydrogen 3.304 N/A LYS 396.A N LEU 392.A O no hydrogen 2.966 N/A LYS 396.A NZ GLU 400.A OE2 no hydrogen 3.079 N/A ARG 397.A N CYS 393.A O no hydrogen 3.193 N/A LEU 399.A N VAL 395.A O no hydrogen 3.342 N/A SER 401.A OG SER 403.A O no hydrogen 3.229 N/A VAL 404.A N ILE 133.A O no hydrogen 3.129 N/A VAL 405.A N GLU 501.A O no hydrogen 2.685 N/A GLY 408.A N GLU 501.A OE2 no hydrogen 2.669 N/A LEU 415.A N VAL 411.A O no hydrogen 3.164 N/A TYR 418.A N ALA 414.A O no hydrogen 3.504 N/A TYR 418.A OH GLU 123.A OE1 no hydrogen 3.374 N/A LEU 419.A N LEU 415.A O no hydrogen 3.310 N/A ASN 421.A N ILE 417.A O no hydrogen 3.280 N/A TYR 422.A N TYR 418.A O no hydrogen 2.885 N/A ALA 423.A N LEU 419.A O no hydrogen 3.074 N/A THR 424.A N GLU 420.A O no hydrogen 3.375 N/A THR 424.A OG1 ASN 421.A O no hydrogen 2.994 N/A SER 425.A N TYR 422.A O no hydrogen 3.203 N/A SER 428.A OG GLY 427.A O no hydrogen 2.800 N/A GLU 430.A N GLY 427.A O no hydrogen 3.378 N/A ALA 435.A N GLN 431.A O no hydrogen 2.988 N/A GLU 436.A N LEU 432.A O no hydrogen 3.272 N/A ALA 438.A N ILE 434.A O no hydrogen 3.078 N/A ARG 439.A N ALA 435.A O no hydrogen 3.446 N/A ARG 439.A NE GLU 436.A OE1 no hydrogen 3.400 N/A ARG 439.A NH2 GLU 436.A OE1 no hydrogen 3.036 N/A SER 440.A N GLU 436.A O no hydrogen 3.107 N/A LEU 442.A N ARG 439.A O no hydrogen 3.394 N/A ASN 446.A N LEU 442.A O no hydrogen 3.225 N/A THR 447.A N VAL 443.A O no hydrogen 2.896 N/A THR 447.A OG1 VAL 443.A O no hydrogen 2.928 N/A THR 447.A OG1 ILE 444.A O no hydrogen 3.477 N/A ALA 449.A N PRO 445.A O no hydrogen 2.935 N/A ASN 451.A ND2 LYS 29.A O no hydrogen 3.608 N/A ASN 451.A ND2 LEU 32.A O no hydrogen 2.939 N/A GLN 454.A N ALA 449.A O no hydrogen 3.334 N/A GLN 454.A NE2 ALA 452.A O no hydrogen 3.176 N/A SER 456.A OG ASN 446.A O no hydrogen 3.561 N/A SER 456.A OG ASN 446.A OD1 no hydrogen 2.296 N/A THR 457.A OG1 ASP 455.A OD1 no hydrogen 2.752 N/A ASP 458.A N ASP 455.A O no hydrogen 3.245 N/A LEU 459.A N ASP 455.A O no hydrogen 3.066 N/A LYS 462.A N ASP 458.A O no hydrogen 3.016 N/A LEU 463.A N VAL 460.A O no hydrogen 3.090 N/A ARG 464.A N VAL 460.A O no hydrogen 3.318 N/A ARG 464.A NE SER 416.A OG no hydrogen 2.866 N/A ARG 464.A NH2 SER 416.A OG no hydrogen 2.785 N/A ALA 465.A N ALA 461.A O no hydrogen 3.079 N/A HIS 467.A N LEU 463.A O no hydrogen 3.174 N/A ASN 468.A N ARG 464.A O no hydrogen 3.172 N/A ASN 468.A ND2 GLU 469.A OE1 no hydrogen 2.831 N/A GLN 471.A N ASN 468.A O no hydrogen 3.168 N/A VAL 472.A N ASN 468.A O no hydrogen 3.234 N/A ARG 476.A NH1 ASN 478.A O no hydrogen 3.532 N/A LYS 477.A NZ ASN 478.A OD1 no hydrogen 3.319 N/A ASN 478.A N GLU 475.A O no hydrogen 3.341 N/A ASN 478.A ND2 ASN 473.A OD1 no hydrogen 2.590 N/A GLY 483.A N ARG 492.A O no hydrogen 2.510 N/A GLY 489.A N ASP 485.A O no hydrogen 3.290 N/A ASN 494.A N TRP 481.A O no hydrogen 2.915 N/A ASN 494.A ND2 GLY 407.A O no hydrogen 2.478 N/A ALA 497.A N ASP 493.A O no hydrogen 3.196 N/A GLY 498.A N ASN 494.A O no hydrogen 2.845 N/A GLU 501.A N VAL 405.A O no hydrogen 2.782 N/A THR 503.A OG1 SER 403.A O no hydrogen 3.437 N/A LYS 506.A N THR 503.A O no hydrogen 3.138 N/A LYS 506.A NZ GLU 412.A OE1 no hydrogen 2.777 N/A LYS 506.A NZ GLU 412.A OE2 no hydrogen 2.958 N/A VAL 507.A N THR 503.A O no hydrogen 2.750 N/A LYS 508.A N ILE 504.A O no hydrogen 3.416 N/A SER 509.A OG VAL 505.A O no hydrogen 2.843 N/A SER 509.A OG LYS 506.A O no hydrogen 2.765 N/A LYS 511.A N VAL 507.A O no hydrogen 3.027 N/A PHE 512.A N LYS 508.A O no hydrogen 3.051 N/A ALA 513.A N SER 509.A O no hydrogen 3.120 N/A GLU 515.A N LYS 511.A O no hydrogen 3.437 N/A ALA 516.A N PHE 512.A O no hydrogen 3.047 N/A ALA 517.A N ALA 513.A O no hydrogen 3.028 N/A ILE 518.A N THR 514.A O no hydrogen 2.970 N/A THR 519.A N GLU 515.A O no hydrogen 3.397 N/A THR 519.A OG1 GLU 515.A O no hydrogen 2.743 N/A ILE 520.A N ALA 516.A O no hydrogen 3.463 N/A LEU 521.A N ALA 517.A O no hydrogen 3.332 N/A ARG 522.A N ILE 518.A O no hydrogen 3.091 N/A ILE 523.A N ILE 520.A O no hydrogen 3.355 N/A LEU 526.A N SER 8.A O no hydrogen 3.002 N/A LYS 528.A NZ ASP 6.A O no hydrogen 3.554 N/A