Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x3j_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A N PRO 1.A O no hydrogen 3.287 N/A PHE 6.A N ALA 2.A O no hydrogen 3.211 N/A ASN 8.A N ILE 4.A O no hydrogen 3.176 N/A SER 10.A N PHE 6.A O no hydrogen 3.050 N/A ALA 11.A N SER 7.A O no hydrogen 3.283 N/A ALA 12.A N ASN 8.A O no hydrogen 3.332 N/A LYS 13.A N ILE 9.A O no hydrogen 2.733 N/A ALA 14.A N SER 10.A O no hydrogen 3.290 N/A ALA 16.A N ALA 12.A O no hydrogen 3.387 N/A ASP 17.A N LYS 13.A O no hydrogen 3.124 N/A ALA 18.A N VAL 15.A O no hydrogen 3.351 N/A ILE 19.A N VAL 15.A O no hydrogen 3.462 N/A THR 21.A OG1 ALA 18.A O no hydrogen 3.226 N/A SER 22.A N ILE 19.A O no hydrogen 3.292 N/A SER 22.A OG SER 22.A O no hydrogen 2.330 N/A SER 22.A OG ASN 43.A O no hydrogen 2.688 N/A MET 28.A N THR 21.A O no hydrogen 2.729 N/A LYS 30.A N ASP 29.A OD1 no hydrogen 2.729 N/A LYS 30.A NZ ALA 18.A O no hydrogen 3.344 N/A ILE 32.A N THR 40.A O no hydrogen 3.174 N/A GLY 37.A N ASP 34.A O no hydrogen 3.458 N/A THR 40.A N ILE 32.A O no hydrogen 2.915 N/A THR 47.A N ASP 44.A O no hydrogen 3.136 N/A THR 47.A N ASP 44.A OD2 no hydrogen 2.767 N/A THR 47.A OG1 ASP 44.A OD2 no hydrogen 2.548 N/A ILE 48.A N ASP 44.A O no hydrogen 3.119 N/A LEU 49.A N GLY 45.A O no hydrogen 3.319 N/A GLN 51.A N THR 47.A O no hydrogen 3.303 N/A GLN 53.A NE2 LYS 50.A O no hydrogen 3.215 N/A ALA 58.A N HIS 56.A ND1 no hydrogen 3.383 N/A ARG 60.A N HIS 56.A O no hydrogen 2.870 N/A MET 61.A N PRO 57.A O no hydrogen 3.083 N/A VAL 63.A N ARG 60.A O no hydrogen 3.260 N/A GLU 64.A N ARG 60.A O no hydrogen 3.267 N/A LEU 65.A N MET 61.A O no hydrogen 2.875 N/A SER 66.A N LEU 62.A O no hydrogen 3.010 N/A SER 66.A OG VAL 63.A O no hydrogen 2.653 N/A LYS 67.A N VAL 63.A O no hydrogen 3.268 N/A ALA 68.A N LEU 65.A O no hydrogen 3.299 N/A ALA 73.A N GLN 69.A O no hydrogen 3.102 N/A GLY 74.A N GLN 69.A O no hydrogen 3.090 N/A THR 77.A OG1 ASP 70.A OD1 no hydrogen 2.785 N/A THR 77.A OG1 ASP 70.A OD2 no hydrogen 3.419 N/A THR 78.A OG1 ILE 19.A O no hydrogen 3.303 N/A SER 79.A OG GLY 76.A O no hydrogen 3.028 N/A VAL 80.A N THR 77.A O no hydrogen 3.399 N/A ALA 84.A N VAL 80.A O no hydrogen 3.143 N/A GLY 85.A N VAL 81.A O no hydrogen 3.157 N/A SER 86.A N ILE 82.A O no hydrogen 3.012 N/A LEU 87.A N ILE 83.A O no hydrogen 3.289 N/A ASP 89.A N GLY 85.A O no hydrogen 3.224 N/A SER 90.A N SER 86.A O no hydrogen 3.179 N/A SER 90.A OG SER 86.A O no hydrogen 3.437 N/A SER 90.A OG LEU 87.A O no hydrogen 2.785 N/A CYS 91.A N LEU 87.A O no hydrogen 2.913 N/A THR 92.A N LEU 88.A O no hydrogen 3.020 N/A THR 92.A N ASP 89.A O no hydrogen 3.296 N/A THR 92.A OG1 LEU 88.A O no hydrogen 2.481 N/A LEU 95.A N CYS 91.A O no hydrogen 2.833 N/A GLN 96.A N THR 92.A O no hydrogen 3.306 N/A LYS 97.A N LEU 94.A O no hydrogen 3.334 N/A THR 102.A N HIS 100.A ND1 no hydrogen 3.422 N/A ILE 103.A N HIS 100.A O no hydrogen 3.282 N/A SER 105.A N PRO 101.A O no hydrogen 3.067 N/A SER 105.A OG PRO 101.A O no hydrogen 3.289 N/A SER 107.A N ILE 103.A O no hydrogen 3.107 N/A SER 107.A OG ILE 103.A O no hydrogen 3.455 N/A SER 107.A OG ILE 104.A O no hydrogen 3.082 N/A PHE 108.A N ILE 104.A O no hydrogen 2.974 N/A GLN 109.A N SER 105.A O no hydrogen 3.360 N/A LYS 110.A N GLU 106.A O no hydrogen 3.375 N/A LYS 110.A NZ GLU 377.A OE2 no hydrogen 2.877 N/A ALA 111.A N SER 107.A O no hydrogen 2.985 N/A LEU 112.A N PHE 108.A O no hydrogen 2.811 N/A GLU 113.A N GLN 109.A O no hydrogen 2.877 N/A LYS 114.A N LYS 110.A O no hydrogen 3.128 N/A GLY 115.A N ALA 111.A O no hydrogen 2.990 N/A ILE 116.A N LEU 112.A O no hydrogen 3.075 N/A ILE 118.A N LYS 114.A O no hydrogen 3.316 N/A LEU 119.A N GLY 115.A O no hydrogen 3.314 N/A THR 120.A OG1 ILE 116.A O no hydrogen 2.339 N/A ASP 121.A N GLU 117.A O no hydrogen 3.391 N/A MET 122.A N ILE 118.A O no hydrogen 3.362 N/A SER 123.A OG LEU 351.A O no hydrogen 2.720 N/A ARG 124.A N LEU 351.A O no hydrogen 2.814 N/A VAL 126.A N ARG 349.A O no hydrogen 3.330 N/A THR 133.A N ASP 130.A OD2 no hydrogen 2.976 N/A THR 133.A OG1 GLU 127.A O no hydrogen 3.356 N/A THR 133.A OG1 ASP 130.A O no hydrogen 2.959 N/A THR 133.A OG1 ASP 130.A OD2 no hydrogen 3.089 N/A LEU 135.A N GLU 132.A O no hydrogen 3.265 N/A ASN 136.A N GLU 132.A O no hydrogen 3.218 N/A SER 137.A N THR 133.A O no hydrogen 3.421 N/A SER 137.A OG THR 133.A O no hydrogen 2.658 N/A SER 137.A OG ASN 136.A OD1 no hydrogen 3.216 N/A THR 139.A N LEU 135.A O no hydrogen 3.206 N/A THR 139.A OG1 SER 151.A O no hydrogen 2.916 N/A THR 140.A OG1 ASN 136.A O no hydrogen 2.361 N/A SER 141.A OG ALA 138.A O no hydrogen 3.543 N/A ASN 143.A N THR 140.A O no hydrogen 3.437 N/A SER 144.A OG SER 141.A O no hydrogen 3.340 N/A LYS 145.A N LEU 142.A O no hydrogen 3.411 N/A SER 148.A OG GLN 149.A OE1 no hydrogen 3.510 N/A SER 151.A OG LEU 142.A O no hydrogen 3.335 N/A SER 151.A OG ASN 143.A OD1 no hydrogen 3.360 N/A SER 151.A OG VAL 147.A O no hydrogen 3.400 N/A SER 151.A OG SER 148.A O no hydrogen 3.021 N/A LEU 153.A N TYR 150.A O no hydrogen 3.402 N/A LEU 154.A N TYR 150.A O no hydrogen 2.978 N/A SER 155.A OG LEU 135.A O no hydrogen 2.874 N/A SER 158.A N SER 155.A O no hydrogen 3.344 N/A SER 158.A OG ALA 338.A O no hydrogen 3.016 N/A VAL 159.A N SER 155.A O no hydrogen 3.220 N/A ASN 160.A N PRO 156.A O no hydrogen 3.184 N/A ILE 166.A N VAL 162.A O no hydrogen 2.846 N/A THR 170.A OG1 PRO 168.A O no hydrogen 2.974 N/A LYS 180.A NZ ASP 262.A OD1 no hydrogen 2.551 N/A LYS 183.A NZ GLU 332.A OE1 no hydrogen 2.445 N/A ASP 190.A N THR 188.A OG1 no hydrogen 3.197 N/A CYS 192.A SG VAL 319.A O no hydrogen 3.836 N/A VAL 195.A N THR 317.A O no hydrogen 2.530 N/A LEU 198.A N ILE 306.A O no hydrogen 3.191 N/A SER 205.A OG ASN 206.A OD1 no hydrogen 2.327 N/A SER 207.A N VAL 204.A O no hydrogen 2.657 N/A SER 207.A OG ILE 252.A O no hydrogen 3.226 N/A THR 210.A OG1 ILE 209.A O no hydrogen 2.733 N/A ARG 211.A NH1 THR 210.A OG1 no hydrogen 2.919 N/A VAL 212.A N ALA 292.A O no hydrogen 3.209 N/A LYS 214.A NZ LYS 214.A O no hydrogen 2.796 N/A ALA 215.A N ALA 289.A O no hydrogen 2.820 N/A LYS 216.A NZ GLY 234.A O no hydrogen 2.447 N/A GLY 218.A N VAL 237.A O no hydrogen 3.372 N/A ILE 220.A N LEU 239.A O no hydrogen 3.146 N/A SER 225.A OG CYS 223.A O no hydrogen 3.242 N/A LYS 231.A N VAL 227.A O no hydrogen 3.282 N/A GLY 234.A N LYS 231.A O no hydrogen 3.329 N/A CYS 235.A SG LYS 216.A O no hydrogen 3.631 N/A CYS 235.A SG VAL 237.A O no hydrogen 3.273 N/A LEU 238.A N MET 253.A O no hydrogen 3.208 N/A ILE 240.A N ILE 255.A O no hydrogen 2.961 N/A LEU 244.A N ASP 241.A O no hydrogen 3.283 N/A ASN 248.A N LEU 244.A O no hydrogen 3.306 N/A ASN 248.A ND2 ASN 206.A O no hydrogen 3.644 N/A ASN 248.A ND2 LEU 244.A O no hydrogen 3.417 N/A MET 250.A N PHE 246.A O no hydrogen 3.356 N/A LYS 251.A N ASN 248.A O no hydrogen 3.382 N/A MET 253.A N ASN 236.A O no hydrogen 2.834 N/A VAL 254.A N SER 207.A OG no hydrogen 3.181 N/A ILE 255.A N LEU 238.A O no hydrogen 3.403 N/A ASP 262.A N GLU 259.A O no hydrogen 3.179 N/A ILE 263.A N ARG 260.A O no hydrogen 3.298 N/A PHE 265.A N ASP 262.A O no hydrogen 3.208 N/A ILE 266.A N ASP 262.A O no hydrogen 3.298 N/A ILE 266.A N ILE 263.A O no hydrogen 3.254 N/A CYS 267.A N ILE 263.A O no hydrogen 3.273 N/A CYS 267.A N GLU 264.A O no hydrogen 3.244 N/A CYS 267.A SG ILE 263.A O no hydrogen 3.239 N/A CYS 267.A SG THR 272.A O no hydrogen 3.672 N/A THR 269.A OG1 PHE 265.A O no hydrogen 3.341 N/A THR 269.A OG1 ILE 266.A O no hydrogen 2.982 N/A THR 272.A OG1 ILE 217.A O no hydrogen 3.470 N/A THR 272.A OG1 LYS 273.A O no hydrogen 3.536 N/A THR 272.A OG1 MET 285.A O no hydrogen 3.386 N/A VAL 275.A N LEU 219.A O no hydrogen 3.016 N/A ALA 276.A N GLN 280.A OE1 no hydrogen 3.196 N/A PHE 281.A N HIS 277.A O no hydrogen 3.160 N/A PHE 281.A N ILE 278.A O no hydrogen 3.150 N/A THR 282.A OG1 GLN 280.A O no hydrogen 3.248 N/A THR 282.A OG1 ASP 284.A OD2 no hydrogen 2.346 N/A ALA 289.A N ALA 215.A O no hydrogen 2.759 N/A GLU 293.A N LYS 305.A O no hydrogen 3.473 N/A GLU 294.A N THR 210.A O no hydrogen 3.283 N/A VAL 295.A N LEU 303.A O no hydrogen 3.227 N/A LEU 297.A N GLY 301.A O no hydrogen 2.981 N/A LEU 304.A N LEU 200.A O no hydrogen 3.225 N/A LYS 305.A N GLU 293.A O no hydrogen 2.964 N/A LYS 305.A NZ GLU 193.A OE2 no hydrogen 2.785 N/A ILE 306.A N LEU 198.A O no hydrogen 3.360 N/A THR 307.A OG1 GLU 290.A OE2 no hydrogen 3.048 N/A CYS 309.A SG GLU 196.A OE1 no hydrogen 3.876 N/A CYS 309.A SG SER 311.A O no hydrogen 3.852 N/A SER 311.A OG ILE 270.A O no hydrogen 3.069 N/A SER 311.A OG CYS 309.A O no hydrogen 2.903 N/A THR 315.A OG1 GLU 196.A O no hydrogen 3.224 N/A THR 317.A N VAL 195.A O no hydrogen 2.572 N/A THR 317.A OG1 GLY 197.A O no hydrogen 3.250 N/A VAL 319.A N GLU 193.A O no hydrogen 2.734 N/A GLY 322.A N GLY 186.A O no hydrogen 3.103 N/A LEU 326.A N ASN 324.A OD1 no hydrogen 3.095 N/A VAL 327.A N ASN 324.A O no hydrogen 3.366 N/A ILE 328.A N ASN 324.A O no hydrogen 3.447 N/A ALA 331.A N VAL 327.A O no hydrogen 2.703 N/A GLU 332.A N ILE 328.A O no hydrogen 2.958 N/A SER 334.A N ALA 331.A O no hydrogen 3.272 N/A ILE 335.A N ALA 331.A O no hydrogen 3.289 N/A HIS 336.A N GLU 332.A O no hydrogen 3.171 N/A ASP 337.A N ARG 333.A O no hydrogen 2.949 N/A ALA 338.A N SER 334.A O no hydrogen 3.179 N/A LEU 339.A N ILE 335.A O no hydrogen 2.527 N/A CYS 340.A N HIS 336.A O no hydrogen 3.049 N/A CYS 340.A SG ALA 73.A O no hydrogen 3.407 N/A CYS 340.A SG GLY 74.A O no hydrogen 3.359 N/A CYS 340.A SG ASP 337.A O no hydrogen 3.320 N/A CYS 340.A SG ASP 337.A OD1 no hydrogen 3.348 N/A ARG 343.A N LEU 339.A O no hydrogen 3.416 N/A ARG 343.A NE VAL 174.A O no hydrogen 2.615 N/A ARG 343.A NH1 GLU 72.A O no hydrogen 2.575 N/A CYS 344.A N CYS 340.A O no hydrogen 3.195 N/A CYS 344.A SG ALA 73.A O no hydrogen 3.820 N/A CYS 344.A SG CYS 340.A O no hydrogen 3.818 N/A LEU 345.A N ILE 342.A O no hydrogen 3.148 N/A VAL 346.A N ILE 342.A O no hydrogen 3.268 N/A ALA 350.A N LYS 348.A O no hydrogen 2.841 N/A LEU 351.A N ARG 124.A O no hydrogen 2.755 N/A ILE 352.A N GLN 440.A O no hydrogen 2.988 N/A ILE 360.A N ALA 357.A O no hydrogen 3.435 N/A LEU 362.A N PRO 358.A O no hydrogen 3.062 N/A ALA 363.A N GLU 359.A O no hydrogen 3.193 N/A ALA 363.A N ILE 360.A O no hydrogen 3.172 N/A LEU 364.A N ILE 360.A O no hydrogen 2.972 N/A ARG 365.A N GLU 361.A O no hydrogen 3.277 N/A ARG 365.A NH1 GLU 368.A OE1 no hydrogen 2.977 N/A THR 367.A OG1 ALA 363.A O no hydrogen 2.650 N/A GLU 368.A N LEU 364.A O no hydrogen 3.326 N/A TYR 369.A N ARG 365.A O no hydrogen 3.126 N/A SER 370.A N LEU 366.A O no hydrogen 3.001 N/A SER 370.A N THR 367.A O no hydrogen 3.195 N/A SER 370.A OG GLU 377.A O no hydrogen 3.309 N/A THR 372.A OG1 TYR 369.A O no hydrogen 3.204 N/A GLU 377.A N SER 374.A O no hydrogen 3.306 N/A CYS 380.A N MET 376.A O no hydrogen 3.145 N/A CYS 380.A SG MET 376.A O no hydrogen 3.275 N/A ALA 383.A N TYR 379.A O no hydrogen 2.839 N/A PHE 384.A N CYS 380.A O no hydrogen 2.795 N/A ALA 385.A N VAL 381.A O no hydrogen 3.018 N/A ASP 386.A N ARG 382.A O no hydrogen 3.079 N/A ALA 387.A N ALA 383.A O no hydrogen 3.156 N/A MET 388.A N ALA 385.A O no hydrogen 3.335 N/A SER 393.A N GLU 389.A O no hydrogen 3.331 N/A THR 394.A N VAL 390.A O no hydrogen 3.006 N/A THR 394.A OG1 VAL 390.A O no hydrogen 2.405 N/A LEU 395.A N ILE 391.A O no hydrogen 2.996 N/A ALA 396.A N PRO 392.A O no hydrogen 3.009 N/A ASN 398.A N THR 394.A O no hydrogen 3.064 N/A ASN 398.A ND2 THR 21.A O no hydrogen 3.483 N/A ASN 398.A ND2 LEU 23.A O no hydrogen 2.456 N/A ALA 399.A N LEU 395.A O no hydrogen 3.182 N/A GLY 400.A N GLU 397.A O no hydrogen 3.399 N/A LEU 401.A N ALA 396.A O no hydrogen 3.199 N/A ILE 404.A N ASN 402.A OD1 no hydrogen 2.902 N/A SER 405.A N ASN 402.A OD1 no hydrogen 2.646 N/A THR 406.A N ASN 402.A O no hydrogen 3.355 N/A THR 406.A OG1 ASN 402.A O no hydrogen 2.442 N/A THR 408.A N ILE 404.A O no hydrogen 3.107 N/A THR 408.A OG1 ILE 404.A O no hydrogen 2.702 N/A GLU 409.A N SER 405.A O no hydrogen 3.174 N/A LEU 410.A N THR 406.A O no hydrogen 2.998 N/A ARG 411.A N VAL 407.A O no hydrogen 2.971 N/A ARG 411.A NE GLU 389.A OE2 no hydrogen 2.968 N/A ARG 411.A NH2 GLU 389.A OE1 no hydrogen 3.237 N/A ARG 411.A NH2 GLU 389.A OE2 no hydrogen 2.815 N/A ARG 413.A N GLU 409.A O no hydrogen 3.377 N/A HIS 414.A N LEU 410.A O no hydrogen 3.102 N/A HIS 414.A ND1 LEU 410.A O no hydrogen 2.860 N/A ALA 415.A N ARG 411.A O no hydrogen 3.191 N/A GLY 417.A N ARG 413.A O no hydrogen 3.044 N/A LYS 419.A NZ MET 122.A O no hydrogen 2.754 N/A THR 420.A OG1 GLU 418.A OE2 no hydrogen 3.256 N/A ILE 423.A N GLY 355.A O no hydrogen 3.189 N/A ASN 424.A N GLY 429.A O no hydrogen 3.075 N/A ARG 426.A NH2 GLU 436.A O no hydrogen 2.705 N/A LYS 427.A NZ GLU 436.A OE1 no hydrogen 3.321 N/A GLY 428.A N ASN 424.A O no hydrogen 2.979 N/A GLY 429.A N ASN 424.A O no hydrogen 3.305 N/A SER 431.A N GLY 422.A O no hydrogen 3.270 N/A SER 431.A OG ILE 430.A O no hydrogen 2.916 N/A ASN 432.A ND2 GLU 435.A OE2 no hydrogen 3.294 N/A ILE 433.A N THR 420.A O no hydrogen 2.708 N/A GLU 435.A N ASN 432.A O no hydrogen 3.274 N/A GLU 436.A N ASN 432.A O no hydrogen 3.323 N/A VAL 438.A N ILE 433.A O no hydrogen 3.387 N/A GLN 440.A N ILE 352.A O no hydrogen 3.002 N/A SER 445.A N LEU 442.A O no hydrogen 3.189 N/A VAL 446.A N LEU 442.A O no hydrogen 3.000 N/A SER 447.A N LEU 443.A O no hydrogen 3.407 N/A SER 447.A OG GLU 72.A OE1 no hydrogen 3.285 N/A SER 447.A OG LEU 443.A O no hydrogen 3.134 N/A LEU 449.A N SER 445.A O no hydrogen 3.145 N/A THR 450.A OG1 VAL 446.A O no hydrogen 2.615 N/A LEU 451.A N SER 447.A O no hydrogen 2.935 N/A ALA 452.A N ALA 448.A O no hydrogen 3.350 N/A THR 453.A N LEU 449.A O no hydrogen 3.312 N/A THR 453.A OG1 LEU 449.A O no hydrogen 2.656 N/A GLU 454.A N THR 450.A O no hydrogen 3.084 N/A THR 455.A N LEU 451.A O no hydrogen 3.181 N/A THR 455.A OG1 LEU 451.A O no hydrogen 2.777 N/A VAL 456.A N ALA 452.A O no hydrogen 3.211 N/A ARG 457.A N THR 453.A O no hydrogen 2.944 N/A ARG 457.A NH1 GLN 109.A OE1 no hydrogen 2.845 N/A SER 458.A N GLU 454.A O no hydrogen 3.008 N/A ILE 459.A N THR 455.A O no hydrogen 2.762 N/A LEU 460.A N VAL 456.A O no hydrogen 2.808 N/A LYS 461.A N ARG 457.A O no hydrogen 3.332 N/A ILE 462.A N ILE 459.A O no hydrogen 3.154 N/A