Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x3j_Z.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 8.A N GLN 5.A O no hydrogen 3.297 N/A VAL 10.A N ALA 6.A O no hydrogen 3.355 N/A ILE 12.A N LEU 8.A O no hydrogen 3.212 N/A SER 13.A OG ALA 9.A O no hydrogen 3.482 N/A ALA 14.A N VAL 10.A O no hydrogen 3.372 N/A ALA 15.A N ASN 11.A O no hydrogen 3.164 N/A ARG 16.A N ILE 12.A O no hydrogen 2.674 N/A GLY 17.A N SER 13.A O no hydrogen 2.761 N/A LEU 18.A N ALA 14.A O no hydrogen 2.991 N/A GLN 19.A N ALA 15.A O no hydrogen 2.997 N/A GLN 19.A NE2 GLU 89.A OE1 no hydrogen 2.878 N/A ASP 20.A N ARG 16.A O no hydrogen 3.206 N/A LEU 22.A N LEU 18.A O no hydrogen 3.410 N/A ARG 23.A NE ASP 20.A OD1 no hydrogen 3.238 N/A THR 24.A OG1 VAL 21.A O no hydrogen 3.289 N/A THR 31.A N THR 24.A O no hydrogen 2.594 N/A THR 31.A OG1 THR 24.A O no hydrogen 2.808 N/A LYS 33.A N THR 45.A O no hydrogen 3.460 N/A LYS 33.A NZ VAL 21.A O no hydrogen 3.108 N/A LYS 33.A NZ THR 24.A OG1 no hydrogen 3.222 N/A LEU 35.A N LYS 43.A O no hydrogen 2.940 N/A SER 37.A N ASP 41.A O no hydrogen 3.276 N/A LYS 43.A NZ ASP 377.A OD2 no hydrogen 3.109 N/A THR 45.A N LYS 33.A O no hydrogen 3.472 N/A LYS 46.A NZ GLY 27.A O no hydrogen 3.318 N/A LYS 46.A NZ PRO 28.A O no hydrogen 3.312 N/A LYS 46.A NZ GLY 30.A O no hydrogen 2.602 N/A LEU 51.A N ASP 47.A O no hydrogen 3.127 N/A LEU 52.A N ASN 49.A O no hydrogen 3.207 N/A HIS 53.A N ASN 49.A O no hydrogen 2.797 N/A GLU 54.A N VAL 50.A O no hydrogen 3.313 N/A MET 55.A N VAL 50.A O no hydrogen 3.389 N/A GLN 56.A NE2 GLU 54.A O no hydrogen 3.188 N/A THR 61.A N HIS 59.A ND1 no hydrogen 3.261 N/A THR 61.A OG1 ASN 11.A OD1 no hydrogen 2.643 N/A SER 63.A N PRO 60.A O no hydrogen 3.261 N/A SER 63.A OG PRO 60.A O no hydrogen 2.411 N/A LEU 64.A N THR 61.A O no hydrogen 3.160 N/A ALA 66.A N ALA 62.A O no hydrogen 3.341 N/A LYS 67.A N LEU 64.A O no hydrogen 3.074 N/A VAL 68.A N ILE 65.A O no hydrogen 3.114 N/A THR 70.A OG1 LYS 67.A O no hydrogen 2.802 N/A ALA 71.A N VAL 68.A O no hydrogen 3.091 N/A GLN 72.A N ALA 69.A O no hydrogen 3.363 N/A THR 76.A N GLN 72.A O no hydrogen 3.407 N/A THR 76.A OG1 GLN 72.A O no hydrogen 2.820 N/A THR 76.A OG1 ASP 78.A O no hydrogen 3.473 N/A THR 81.A OG1 ASN 25.A OD1 no hydrogen 3.433 N/A ASN 83.A N THR 80.A O no hydrogen 3.318 N/A ASN 83.A ND2 SER 495.A OG no hydrogen 3.355 N/A GLY 88.A N VAL 84.A O no hydrogen 2.948 N/A LEU 90.A N ILE 86.A O no hydrogen 2.776 N/A LEU 91.A N ILE 87.A O no hydrogen 3.369 N/A LYS 92.A N GLY 88.A O no hydrogen 3.290 N/A GLN 93.A N GLU 89.A O no hydrogen 2.926 N/A GLN 93.A NE2 GLU 89.A OE2 no hydrogen 3.227 N/A ALA 94.A N LEU 90.A O no hydrogen 3.270 N/A ASP 95.A N LYS 92.A O no hydrogen 3.290 N/A TYR 97.A N ALA 94.A O no hydrogen 3.243 N/A ILE 98.A N ALA 94.A O no hydrogen 3.117 N/A GLY 101.A N ILE 98.A O no hydrogen 3.073 N/A LEU 102.A N TYR 97.A O no hydrogen 3.316 N/A ARG 105.A N HIS 103.A ND1 no hydrogen 3.308 N/A ILE 106.A N HIS 103.A O no hydrogen 3.307 N/A THR 108.A N PRO 104.A O no hydrogen 3.143 N/A THR 108.A OG1 PRO 104.A O no hydrogen 2.951 N/A GLU 109.A N ARG 105.A O no hydrogen 2.963 N/A GLY 110.A N ILE 106.A O no hydrogen 3.099 N/A GLY 110.A N ILE 107.A O no hydrogen 3.241 N/A PHE 111.A N ILE 107.A O no hydrogen 2.956 N/A PHE 111.A N THR 108.A O no hydrogen 3.219 N/A GLU 112.A N THR 108.A O no hydrogen 3.303 N/A ALA 114.A N GLY 110.A O no hydrogen 3.161 N/A LYS 115.A N PHE 111.A O no hydrogen 3.029 N/A GLU 116.A N GLU 112.A O no hydrogen 3.425 N/A ALA 118.A N ALA 114.A O no hydrogen 3.191 N/A LEU 119.A N LYS 115.A O no hydrogen 3.080 N/A GLN 120.A N GLU 116.A O no hydrogen 3.274 N/A PHE 121.A N LYS 117.A O no hydrogen 3.083 N/A LEU 122.A N ALA 118.A O no hydrogen 3.203 N/A GLU 124.A N PHE 121.A O no hydrogen 3.371 N/A LYS 126.A NZ GLU 123.A OE1 no hydrogen 2.986 N/A VAL 127.A N VAL 395.A O no hydrogen 2.814 N/A ARG 133.A NH2 ASP 162.A OD2 no hydrogen 3.432 N/A ILE 137.A N GLU 134.A O no hydrogen 3.367 N/A ALA 140.A N LEU 136.A O no hydrogen 3.079 N/A ARG 141.A N ILE 137.A O no hydrogen 2.765 N/A THR 142.A N ASP 138.A O no hydrogen 3.353 N/A THR 142.A OG1 VAL 139.A O no hydrogen 2.880 N/A THR 142.A OG1 TRP 483.A O no hydrogen 2.958 N/A SER 143.A OG ALA 140.A O no hydrogen 3.429 N/A LEU 144.A N ALA 140.A O no hydrogen 3.042 N/A ARG 145.A NE ARG 141.A O no hydrogen 2.542 N/A THR 146.A OG1 SER 143.A O no hydrogen 3.135 N/A LYS 147.A N LEU 144.A O no hydrogen 3.491 N/A LEU 156.A N LEU 152.A O no hydrogen 3.266 N/A THR 157.A OG1 ASP 154.A O no hydrogen 3.184 N/A THR 157.A OG1 GLU 158.A OE1 no hydrogen 2.702 N/A VAL 160.A N THR 157.A O no hydrogen 3.344 N/A VAL 161.A N THR 157.A O no hydrogen 3.030 N/A SER 163.A OG ALA 159.A O no hydrogen 3.326 N/A SER 163.A OG VAL 160.A O no hydrogen 2.889 N/A ILE 164.A N VAL 160.A O no hydrogen 3.473 N/A LEU 165.A N VAL 161.A O no hydrogen 3.064 N/A ALA 166.A N ASP 162.A O no hydrogen 3.290 N/A LYS 169.A NZ ALA 166.A O no hydrogen 2.455 N/A GLU 172.A N LYS 169.A O no hydrogen 3.320 N/A ILE 179.A N LEU 176.A O no hydrogen 3.327 N/A GLU 180.A N VAL 360.A O no hydrogen 3.118 N/A MET 182.A N LEU 362.A O no hydrogen 3.337 N/A MET 184.A N ILE 364.A O no hydrogen 3.401 N/A THR 192.A OG1 LEU 363.A O no hydrogen 2.516 N/A SER 193.A N LEU 363.A O no hydrogen 3.291 N/A ILE 195.A N THR 361.A O no hydrogen 3.034 N/A ARG 196.A NH2 CYS 354.A O no hydrogen 2.888 N/A HIS 202.A N ASP 201.A OD1 no hydrogen 2.860 N/A ARG 205.A NH1 ALA 204.A O no hydrogen 2.911 N/A ARG 205.A NH2 LYS 347.A O no hydrogen 3.102 N/A HIS 206.A NE2 ASP 291.A OD1 no hydrogen 2.447 N/A ARG 212.A NE GLU 214.A OE2 no hydrogen 3.129 N/A ARG 212.A NH2 GLU 214.A OE1 no hydrogen 3.384 N/A VAL 213.A N VAL 338.A O no hydrogen 2.707 N/A TYR 217.A N GLY 276.A O no hydrogen 3.146 N/A ILE 218.A N GLY 333.A O no hydrogen 3.372 N/A LEU 219.A N VAL 278.A O no hydrogen 3.343 N/A CYS 221.A SG LEU 219.A O no hydrogen 3.404 N/A LEU 225.A N GLY 284.A O no hydrogen 3.127 N/A THR 230.A OG1 VAL 232.A O no hydrogen 3.048 N/A SER 234.A OG GLY 235.A O no hydrogen 3.339 N/A GLY 235.A N SER 234.A OG no hydrogen 2.450 N/A LYS 246.A N GLU 242.A O no hydrogen 3.375 N/A LYS 246.A NZ LYS 246.A O no hydrogen 2.894 N/A LEU 247.A N GLU 243.A O no hydrogen 2.931 N/A VAL 248.A N ARG 244.A O no hydrogen 2.808 N/A ALA 250.A N LYS 246.A O no hydrogen 3.123 N/A GLU 251.A N LEU 247.A O no hydrogen 2.897 N/A ARG 252.A N VAL 248.A O no hydrogen 3.159 N/A ILE 255.A N ARG 252.A O no hydrogen 2.888 N/A GLU 256.A N ARG 252.A O no hydrogen 3.403 N/A ARG 258.A N ILE 255.A O no hydrogen 3.004 N/A VAL 259.A N ILE 255.A O no hydrogen 3.253 N/A LYS 260.A N GLU 256.A O no hydrogen 3.168 N/A LYS 261.A NZ GLU 264.A OE1 no hydrogen 3.457 N/A ILE 262.A N VAL 259.A O no hydrogen 3.326 N/A GLU 264.A N LYS 260.A O no hydrogen 3.152 N/A LEU 265.A N LYS 261.A O no hydrogen 2.975 N/A LYS 266.A N ILE 262.A O no hydrogen 2.880 N/A LYS 266.A NZ GLU 296.A O no hydrogen 2.713 N/A ARG 267.A N ILE 263.A O no hydrogen 2.990 N/A LYS 268.A N GLU 264.A O no hydrogen 3.208 N/A VAL 269.A N LEU 265.A O no hydrogen 3.317 N/A LYS 275.A NZ SER 273.A O no hydrogen 3.316 N/A VAL 278.A N TYR 217.A O no hydrogen 3.487 N/A VAL 279.A N VAL 299.A O no hydrogen 2.830 N/A ASN 281.A ND2 VAL 223.A O no hydrogen 3.298 N/A GLN 282.A N CYS 221.A O no hydrogen 3.423 N/A GLN 282.A NE2 ALA 304.A O no hydrogen 3.080 N/A LYS 283.A NZ GLN 282.A OE1 no hydrogen 2.613 N/A SER 289.A N ASP 286.A O no hydrogen 2.980 N/A LEU 290.A N ASP 286.A O no hydrogen 3.253 N/A LEU 290.A N PRO 287.A O no hydrogen 3.366 N/A SER 294.A N LEU 290.A O no hydrogen 3.298 N/A ILE 298.A N LEU 293.A O no hydrogen 3.013 N/A VAL 299.A N PHE 277.A O no hydrogen 3.258 N/A LEU 301.A N VAL 279.A O no hydrogen 2.903 N/A ARG 302.A NH1 ILE 285.A O no hydrogen 2.973 N/A ARG 303.A NH2 GLU 226.A OE2 no hydrogen 3.254 N/A ALA 304.A N GLN 282.A O no hydrogen 3.093 N/A ARG 307.A NE GLU 180.A OE1 no hydrogen 3.402 N/A ARG 307.A NH2 GLU 180.A OE1 no hydrogen 3.053 N/A ARG 307.A NH2 GLU 180.A OE2 no hydrogen 2.728 N/A ARG 311.A N ARG 307.A O no hydrogen 3.386 N/A ARG 311.A NH1 MET 178.A O no hydrogen 3.060 N/A LEU 312.A N ASN 308.A O no hydrogen 2.926 N/A THR 313.A N MET 309.A O no hydrogen 3.100 N/A THR 313.A N GLU 310.A O no hydrogen 3.269 N/A THR 313.A OG1 MET 309.A O no hydrogen 2.747 N/A LEU 314.A N GLU 310.A O no hydrogen 3.378 N/A ALA 315.A N ARG 311.A O no hydrogen 3.052 N/A CYS 316.A N LEU 312.A O no hydrogen 3.261 N/A CYS 316.A SG LEU 312.A O no hydrogen 3.334 N/A SER 328.A OG ASP 330.A OD2 no hydrogen 2.953 N/A CYS 331.A N SER 328.A O no hydrogen 3.391 N/A CYS 331.A SG VAL 319.A O no hydrogen 3.647 N/A LEU 332.A N PRO 329.A O no hydrogen 3.377 N/A GLY 333.A N ILE 218.A O no hydrogen 2.538 N/A HIS 334.A N CYS 316.A O no hydrogen 3.364 N/A HIS 334.A ND1 ALA 216.A O no hydrogen 3.029 N/A ALA 335.A N ALA 216.A O no hydrogen 3.438 N/A VAL 338.A N VAL 213.A O no hydrogen 2.712 N/A TYR 339.A N PHE 350.A O no hydrogen 2.991 N/A TYR 339.A OH GLU 352.A OE2 no hydrogen 3.185 N/A GLU 340.A N LYS 211.A O no hydrogen 3.409 N/A TYR 341.A N PHE 348.A O no hydrogen 2.589 N/A THR 342.A OG1 LEU 343.A O no hydrogen 3.285 N/A LEU 343.A N GLU 346.A O no hydrogen 3.002 N/A PHE 348.A N TYR 341.A O no hydrogen 2.910 N/A THR 349.A OG1 GLU 340.A OE2 no hydrogen 2.528 N/A PHE 350.A N TYR 339.A O no hydrogen 2.726 N/A GLU 352.A N GLU 352.A OE1 no hydrogen 2.767 N/A CYS 354.A SG ILE 351.A O no hydrogen 3.405 N/A ARG 358.A NH1 GLU 172.A OE2 no hydrogen 3.536 N/A ARG 358.A NH2 GLU 172.A OE2 no hydrogen 2.789 N/A SER 359.A OG MET 178.A O no hydrogen 2.675 N/A VAL 360.A N MET 178.A O no hydrogen 3.338 N/A THR 361.A N ILE 195.A O no hydrogen 3.289 N/A THR 361.A OG1 GLY 197.A O no hydrogen 3.141 N/A LEU 362.A N GLU 180.A O no hydrogen 2.832 N/A LEU 363.A N SER 193.A O no hydrogen 3.195 N/A ILE 364.A N MET 182.A O no hydrogen 3.329 N/A LYS 365.A NZ ASP 191.A OD2 no hydrogen 3.117 N/A LYS 365.A NZ TYR 341.A OH no hydrogen 3.230 N/A GLY 366.A N MET 184.A O no hydrogen 3.404 N/A ASN 368.A ND2 THR 371.A OG1 no hydrogen 3.087 N/A LEU 372.A N LYS 369.A O no hydrogen 3.248 N/A THR 373.A OG1 HIS 370.A O no hydrogen 3.313 N/A GLN 374.A N HIS 370.A O no hydrogen 3.322 N/A GLN 374.A NE2 LYS 147.A O no hydrogen 3.209 N/A ILE 375.A N THR 371.A O no hydrogen 3.369 N/A LYS 376.A N LEU 372.A O no hydrogen 3.192 N/A ASP 377.A N THR 373.A O no hydrogen 3.193 N/A ALA 378.A N ILE 375.A O no hydrogen 3.039 N/A VAL 379.A N ILE 375.A O no hydrogen 2.741 N/A ARG 380.A NE LYS 376.A O no hydrogen 3.354 N/A ARG 380.A NH2 ASP 377.A OD1 no hydrogen 2.695 N/A GLY 382.A N ALA 378.A O no hydrogen 2.909 N/A LEU 383.A N VAL 379.A O no hydrogen 2.985 N/A ARG 384.A NE ARG 380.A O no hydrogen 3.118 N/A VAL 386.A N GLY 382.A O no hydrogen 3.351 N/A LYS 387.A N LEU 383.A O no hydrogen 3.019 N/A ASN 388.A N ARG 384.A O no hydrogen 3.166 N/A ASN 388.A ND2 THR 76.A O no hydrogen 2.920 N/A ALA 389.A N VAL 386.A O no hydrogen 2.933 N/A ILE 390.A N VAL 386.A O no hydrogen 3.011 N/A ASP 391.A N LYS 387.A O no hydrogen 3.320 N/A CYS 394.A SG ASP 392.A OD1 no hydrogen 3.298 N/A CYS 394.A SG ASP 392.A OD2 no hydrogen 3.726 N/A VAL 395.A N VAL 127.A O no hydrogen 3.054 N/A VAL 396.A N ASP 484.A O no hydrogen 3.009 N/A GLY 398.A N VAL 482.A O no hydrogen 2.999 N/A ALA 401.A N GLY 398.A O no hydrogen 3.146 N/A VAL 404.A N GLY 400.A O no hydrogen 3.470 N/A ALA 405.A N ALA 401.A O no hydrogen 3.335 N/A MET 406.A N VAL 402.A O no hydrogen 2.821 N/A ALA 407.A N GLU 403.A O no hydrogen 3.204 N/A ALA 407.A N VAL 404.A O no hydrogen 3.228 N/A ALA 409.A N ALA 405.A O no hydrogen 3.375 N/A LEU 410.A N MET 406.A O no hydrogen 3.089 N/A LYS 412.A N GLU 408.A O no hydrogen 3.345 N/A LYS 418.A NZ GLU 109.A OE1 no hydrogen 2.480 N/A GLN 422.A N GLY 419.A O no hydrogen 3.379 N/A GLY 424.A N ALA 421.A O no hydrogen 3.150 N/A GLN 426.A N GLN 422.A O no hydrogen 3.253 N/A ALA 427.A N LEU 423.A O no hydrogen 2.947 N/A PHE 428.A N GLY 424.A O no hydrogen 3.396 N/A ALA 429.A N VAL 425.A O no hydrogen 3.292 N/A ASP 430.A N GLN 426.A O no hydrogen 3.260 N/A ALA 431.A N ALA 427.A O no hydrogen 3.094 N/A LEU 433.A N ASP 430.A O no hydrogen 3.419 N/A VAL 438.A N ILE 434.A O no hydrogen 2.757 N/A LEU 439.A N ILE 435.A O no hydrogen 3.244 N/A ASN 442.A N VAL 438.A O no hydrogen 3.269 N/A ASN 442.A ND2 ARG 23.A O no hydrogen 3.243 N/A ASN 442.A ND2 LEU 26.A O no hydrogen 2.906 N/A SER 443.A OG LEU 439.A O no hydrogen 3.420 N/A SER 443.A OG ALA 440.A O no hydrogen 3.238 N/A GLY 444.A N GLN 441.A O no hydrogen 3.415 N/A PHE 445.A N ALA 440.A O no hydrogen 2.969 N/A GLN 448.A N ASP 446.A OD2 no hydrogen 2.974 N/A GLU 449.A N ASP 446.A OD2 no hydrogen 3.094 N/A THR 450.A OG1 GLY 472.A O no hydrogen 3.219 N/A ILE 454.A N THR 450.A O no hydrogen 3.072 N/A GLN 455.A N VAL 452.A O no hydrogen 3.162 N/A ALA 456.A N VAL 452.A O no hydrogen 2.867 N/A SER 459.A OG GLN 463.A OE1 no hydrogen 2.597 N/A GLY 466.A N MET 475.A O no hydrogen 2.707 N/A VAL 467.A N ALA 399.A O no hydrogen 3.412 N/A ASN 470.A N ASP 468.A OD2 no hydrogen 2.792 N/A THR 471.A N ASP 468.A OD2 no hydrogen 2.781 N/A MET 475.A N GLY 466.A O no hydrogen 2.875 N/A GLY 481.A N ALA 477.A O no hydrogen 3.275 N/A VAL 482.A N ALA 477.A O no hydrogen 3.099 N/A ASP 484.A N VAL 396.A O no hydrogen 2.780 N/A ASN 485.A ND2 ALA 385.A O no hydrogen 2.976 N/A LYS 489.A N ASN 485.A O no hydrogen 3.380 N/A LYS 489.A NZ GLU 403.A OE2 no hydrogen 3.328 N/A LYS 490.A N TYR 486.A O no hydrogen 2.970 N/A GLN 491.A N CYS 487.A O no hydrogen 3.186 N/A LEU 492.A N VAL 488.A O no hydrogen 2.891 N/A LEU 493.A N LYS 489.A O no hydrogen 3.390 N/A HIS 494.A N LYS 490.A O no hydrogen 3.377 N/A SER 495.A N GLN 491.A O no hydrogen 3.060 N/A SER 495.A OG GLN 72.A OE1 no hydrogen 3.454 N/A CYS 496.A N LEU 492.A O no hydrogen 3.180 N/A CYS 496.A SG ASN 83.A O no hydrogen 4.044 N/A CYS 496.A SG ASN 83.A OD1 no hydrogen 3.241 N/A CYS 496.A SG LEU 492.A O no hydrogen 3.282 N/A THR 497.A OG1 LEU 493.A O no hydrogen 2.785 N/A ILE 499.A N SER 495.A O no hydrogen 3.271 N/A ALA 500.A N CYS 496.A O no hydrogen 3.301 N/A THR 501.A OG1 THR 497.A O no hydrogen 2.760 N/A ASN 502.A N VAL 498.A O no hydrogen 3.286 N/A ILE 503.A N ILE 499.A O no hydrogen 3.314 N/A LEU 504.A N ALA 500.A O no hydrogen 3.409 N/A