Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x3u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 6.A N LYS 432.A O no hydrogen 3.118 N/A SER 8.A N LEU 430.A O no hydrogen 3.058 N/A THR 9.A OG1 ASP 428.A O no hydrogen 2.604 N/A SER 15.A N GLU 11.A O no hydrogen 3.028 N/A SER 15.A OG GLU 11.A O no hydrogen 2.847 N/A SER 15.A OG ASP 101.A OD1 no hydrogen 3.051 N/A GLN 16.A N THR 12.A O no hydrogen 2.681 N/A ASN 17.A N ILE 13.A O no hydrogen 3.100 N/A VAL 18.A N ARG 14.A O no hydrogen 2.937 N/A MET 19.A N SER 15.A O no hydrogen 2.644 N/A ALA 20.A N GLN 16.A O no hydrogen 2.949 N/A ALA 21.A N ASN 17.A O no hydrogen 3.115 N/A ALA 22.A N VAL 18.A O no hydrogen 2.918 N/A SER 23.A N MET 19.A O no hydrogen 3.344 N/A SER 23.A N ALA 20.A O no hydrogen 3.165 N/A SER 23.A OG MET 19.A O no hydrogen 3.062 N/A ILE 24.A N ALA 20.A O no hydrogen 3.393 N/A ALA 25.A N ALA 21.A O no hydrogen 3.227 N/A ASN 26.A N ALA 22.A O no hydrogen 3.099 N/A ILE 27.A N SER 23.A O no hydrogen 3.184 N/A VAL 28.A N ALA 25.A O no hydrogen 2.862 N/A LEU 32.A N LYS 29.A O no hydrogen 3.272 N/A GLY 36.A N GLY 33.A O no hydrogen 3.337 N/A LEU 37.A N SER 30.A O no hydrogen 3.418 N/A LYS 39.A N THR 51.A O no hydrogen 2.753 N/A LYS 39.A NZ SER 30.A OG no hydrogen 2.510 N/A ASP 43.A N ASP 47.A O no hydrogen 3.317 N/A GLY 46.A N ASP 43.A OD1 no hydrogen 3.057 N/A THR 49.A N LEU 41.A O no hydrogen 3.215 N/A THR 51.A N LYS 39.A O no hydrogen 3.299 N/A ASN 52.A ND2 ASP 38.A OD1 no hydrogen 3.514 N/A THR 56.A N ASP 53.A OD2 no hydrogen 2.856 N/A THR 56.A OG1 ASP 53.A OD2 no hydrogen 2.773 N/A ILE 57.A N ASP 53.A O no hydrogen 3.123 N/A LEU 58.A N GLY 54.A O no hydrogen 3.245 N/A LYS 59.A N ALA 55.A O no hydrogen 3.239 N/A LEU 60.A N THR 56.A O no hydrogen 3.277 N/A LEU 61.A N ILE 57.A O no hydrogen 2.591 N/A ALA 67.A N HIS 65.A ND1 no hydrogen 3.307 N/A LYS 69.A N HIS 65.A O no hydrogen 3.186 N/A VAL 70.A N PRO 66.A O no hydrogen 3.223 N/A VAL 70.A N ALA 67.A O no hydrogen 3.197 N/A CYS 72.A N ALA 68.A O no hydrogen 3.197 N/A CYS 72.A SG ALA 68.A O no hydrogen 3.608 N/A GLU 73.A N LYS 69.A O no hydrogen 2.973 N/A LEU 74.A N VAL 70.A O no hydrogen 2.773 N/A ALA 75.A N LEU 71.A O no hydrogen 2.968 N/A ASP 76.A N CYS 72.A O no hydrogen 3.280 N/A LEU 77.A N GLU 73.A O no hydrogen 3.243 N/A GLN 78.A N LEU 74.A O no hydrogen 3.151 N/A GLN 78.A NE2 ASP 84.A O no hydrogen 2.864 N/A ASP 79.A N ALA 75.A O no hydrogen 2.888 N/A LYS 80.A N ASP 76.A O no hydrogen 2.908 N/A GLU 81.A N LEU 77.A O no hydrogen 3.069 N/A VAL 82.A N GLN 78.A O no hydrogen 3.071 N/A GLY 83.A N GLN 78.A O no hydrogen 3.114 N/A SER 88.A OG GLY 85.A O no hydrogen 3.083 N/A VAL 89.A N GLY 85.A O no hydrogen 3.199 N/A VAL 90.A N THR 86.A O no hydrogen 3.365 N/A ILE 91.A N THR 87.A O no hydrogen 3.135 N/A ILE 92.A N SER 88.A O no hydrogen 2.825 N/A ALA 93.A N VAL 89.A O no hydrogen 3.042 N/A ALA 94.A N VAL 90.A O no hydrogen 3.235 N/A GLU 95.A N ILE 91.A O no hydrogen 3.216 N/A LEU 96.A N ILE 92.A O no hydrogen 3.113 N/A LEU 97.A N ALA 93.A O no hydrogen 3.055 N/A LYS 98.A N ALA 94.A O no hydrogen 2.909 N/A ASN 99.A N GLU 95.A O no hydrogen 2.958 N/A ASN 99.A ND2 GLU 340.A O no hydrogen 3.512 N/A ALA 100.A N LEU 96.A O no hydrogen 2.748 N/A ASP 101.A N LEU 97.A O no hydrogen 2.867 N/A GLU 102.A N LYS 98.A O no hydrogen 3.244 N/A LEU 103.A N ASN 99.A O no hydrogen 3.058 N/A VAL 104.A N ALA 100.A O no hydrogen 2.973 N/A LYS 105.A N ASP 101.A O no hydrogen 3.285 N/A LYS 105.A NZ ASP 101.A OD2 no hydrogen 3.226 N/A GLN 106.A N GLU 102.A O no hydrogen 3.281 N/A GLN 106.A N LEU 103.A O no hydrogen 2.754 N/A LYS 107.A N VAL 104.A O no hydrogen 3.292 N/A ILE 108.A N LEU 103.A O no hydrogen 3.113 N/A THR 111.A N HIS 109.A ND1 no hydrogen 3.336 N/A SER 112.A N HIS 109.A O no hydrogen 3.125 N/A VAL 113.A N HIS 109.A O no hydrogen 3.136 N/A ILE 114.A N PRO 110.A O no hydrogen 2.608 N/A SER 115.A N THR 111.A O no hydrogen 3.050 N/A SER 115.A OG THR 111.A O no hydrogen 3.261 N/A GLY 116.A N SER 112.A O no hydrogen 3.239 N/A GLY 116.A N VAL 113.A O no hydrogen 3.260 N/A TYR 117.A N VAL 113.A O no hydrogen 3.127 N/A TYR 117.A OH LEU 96.A O no hydrogen 3.016 N/A ARG 118.A N ILE 114.A O no hydrogen 3.113 N/A ALA 120.A N GLY 116.A O no hydrogen 2.755 N/A CYS 121.A N TYR 117.A O no hydrogen 3.007 N/A LYS 122.A N ARG 118.A O no hydrogen 3.355 N/A GLU 123.A N LEU 119.A O no hydrogen 3.042 N/A ALA 124.A N ALA 120.A O no hydrogen 2.954 N/A VAL 125.A N CYS 121.A O no hydrogen 3.176 N/A ARG 126.A N LYS 122.A O no hydrogen 3.193 N/A TYR 127.A N GLU 123.A O no hydrogen 2.842 N/A TYR 127.A OH GLN 375.A OE1 no hydrogen 2.472 N/A ILE 128.A N ALA 124.A O no hydrogen 2.875 N/A ASN 129.A N VAL 125.A O no hydrogen 3.009 N/A GLU 130.A N ARG 126.A O no hydrogen 3.126 N/A ASN 131.A N ILE 128.A O no hydrogen 3.120 N/A ASN 131.A ND2 TYR 127.A O no hydrogen 3.559 N/A ALA 141.A N CYS 137.A O no hydrogen 2.678 N/A THR 144.A OG1 ASN 140.A O no hydrogen 3.372 N/A THR 144.A OG1 ALA 401.A O no hydrogen 2.517 N/A MET 146.A N ALA 142.A O no hydrogen 3.002 N/A ILE 150.A N ILE 147.A O no hydrogen 3.422 N/A ASN 151.A N ILE 148.A O no hydrogen 3.443 N/A PHE 155.A N ASN 151.A O no hydrogen 3.439 N/A ALA 156.A N GLY 152.A O no hydrogen 2.915 N/A ASN 157.A N ASP 153.A O no hydrogen 3.079 N/A VAL 159.A N ALA 156.A O no hydrogen 2.958 N/A VAL 160.A N ALA 156.A O no hydrogen 3.289 N/A ALA 162.A N MET 158.A O no hydrogen 3.128 N/A VAL 163.A N VAL 159.A O no hydrogen 2.930 N/A LEU 164.A N VAL 160.A O no hydrogen 3.168 N/A ALA 165.A N ASP 161.A O no hydrogen 3.033 N/A LYS 167.A N LEU 164.A O no hydrogen 3.104 N/A ASP 170.A N THR 169.A OG1 no hydrogen 2.619 N/A GLN 174.A N ILE 171.A O no hydrogen 2.538 N/A TYR 177.A N GLU 304.A OE2 no hydrogen 3.267 N/A SER 181.A N VAL 179.A O no hydrogen 2.875 N/A LEU 185.A N ILE 275.A O no hydrogen 3.284 N/A LYS 186.A NZ ASP 282.A OD1 no hydrogen 3.062 N/A LYS 186.A NZ ASP 286.A OD2 no hydrogen 3.171 N/A ALA 187.A N LEU 277.A O no hydrogen 2.482 N/A ARG 190.A N HIS 188.A O no hydrogen 3.305 N/A ARG 190.A NE ARG 190.A O no hydrogen 3.046 N/A MET 193.A N SER 191.A OG no hydrogen 2.723 N/A GLU 194.A N SER 191.A OG no hydrogen 2.988 N/A SER 195.A OG GLN 192.A O no hydrogen 3.552 N/A SER 195.A OG ARG 278.A O no hydrogen 3.318 N/A MET 196.A N ILE 276.A O no hydrogen 3.335 N/A ILE 198.A N SER 274.A O no hydrogen 2.543 N/A LEU 203.A N ILE 269.A O no hydrogen 3.033 N/A ASN 204.A ND2 ASP 266.A OD1 no hydrogen 3.355 N/A CYS 205.A N LEU 203.A O no hydrogen 2.977 N/A ASN 210.A ND2 ASN 221.A OD1 no hydrogen 2.549 N/A LYS 212.A N ASN 210.A OD1 no hydrogen 3.209 N/A ALA 214.A N VAL 222.A O no hydrogen 3.082 N/A CYS 215.A SG ILE 213.A O no hydrogen 3.549 N/A LEU 216.A N LEU 224.A O no hydrogen 3.425 N/A SER 219.A OG GLY 227.A O no hydrogen 2.133 N/A LEU 220.A N GLY 228.A O no hydrogen 3.214 N/A ASN 221.A ND2 GLY 241.A O no hydrogen 2.684 N/A LEU 224.A N ALA 214.A O no hydrogen 3.241 N/A THR 225.A N VAL 245.A O no hydrogen 3.267 N/A THR 226.A OG1 ASP 217.A O no hydrogen 2.821 N/A ASP 231.A N ASP 230.A OD2 no hydrogen 2.718 N/A CYS 233.A SG LEU 220.A O no hydrogen 3.789 N/A LYS 235.A N MET 232.A O no hydrogen 3.141 N/A VAL 238.A N LEU 234.A O no hydrogen 3.359 N/A GLU 239.A N TYR 236.A O no hydrogen 3.235 N/A ALA 240.A N TYR 236.A O no hydrogen 3.464 N/A GLY 241.A N PHE 237.A O no hydrogen 2.641 N/A ALA 242.A N PHE 237.A O no hydrogen 2.902 N/A VAL 245.A N ILE 223.A O no hydrogen 3.041 N/A VAL 248.A N THR 225.A O no hydrogen 2.941 N/A LEU 253.A N LEU 249.A O no hydrogen 3.210 N/A LYS 254.A N LYS 250.A O no hydrogen 3.255 N/A ARG 255.A N ARG 251.A O no hydrogen 3.431 N/A ARG 255.A NE ARG 251.A O no hydrogen 3.309 N/A ILE 256.A N ASP 252.A O no hydrogen 2.726 N/A ALA 257.A N LEU 253.A O no hydrogen 2.655 N/A LYS 258.A N LYS 254.A O no hydrogen 2.926 N/A ALA 259.A N ARG 255.A O no hydrogen 2.537 N/A SER 260.A N ILE 256.A O no hydrogen 2.661 N/A SER 260.A OG ILE 256.A O no hydrogen 3.302 N/A ILE 269.A N LEU 203.A O no hydrogen 2.592 N/A ILE 271.A N TYR 201.A O no hydrogen 3.191 N/A SER 274.A N ILE 198.A O no hydrogen 2.804 N/A SER 274.A OG ASN 183.A O no hydrogen 2.488 N/A ILE 276.A N MET 196.A O no hydrogen 3.303 N/A LEU 277.A N LEU 185.A O no hydrogen 3.135 N/A ARG 278.A NE GLU 194.A O no hydrogen 3.251 N/A GLY 279.A N ALA 187.A O no hydrogen 2.695 N/A ASP 282.A N ASN 281.A OD1 no hydrogen 2.535 N/A CYS 285.A N ASN 281.A O no hydrogen 3.325 N/A CYS 285.A SG ALA 187.A O no hydrogen 3.786 N/A CYS 285.A SG ASN 281.A O no hydrogen 3.297 N/A CYS 285.A SG ASP 282.A O no hydrogen 3.818 N/A ASP 286.A N ASP 282.A O no hydrogen 3.091 N/A MET 288.A N MET 284.A O no hydrogen 3.409 N/A GLU 289.A N CYS 285.A O no hydrogen 3.136 N/A GLU 289.A N ASP 286.A O no hydrogen 3.236 N/A ARG 290.A NH1 ASP 286.A OD1 no hydrogen 3.475 N/A SER 291.A N GLU 287.A O no hydrogen 3.019 N/A SER 291.A OG GLU 287.A O no hydrogen 2.557 N/A LEU 292.A N MET 288.A O no hydrogen 3.100 N/A LEU 292.A N GLU 289.A O no hydrogen 3.268 N/A HIS 293.A N GLU 289.A O no hydrogen 3.284 N/A ASP 294.A N ARG 290.A O no hydrogen 2.961 N/A ALA 295.A N SER 291.A O no hydrogen 3.446 N/A LEU 296.A N LEU 292.A O no hydrogen 2.920 N/A CYS 297.A N HIS 293.A O no hydrogen 3.384 N/A CYS 297.A N ASP 294.A O no hydrogen 3.043 N/A CYS 297.A SG HIS 293.A O no hydrogen 3.232 N/A VAL 298.A N ASP 294.A O no hydrogen 3.280 N/A VAL 299.A N ALA 295.A O no hydrogen 3.179 N/A LYS 300.A N LEU 296.A O no hydrogen 2.943 N/A ARG 301.A N CYS 297.A O no hydrogen 2.721 N/A ARG 301.A NH1 ASP 84.A OD2 no hydrogen 2.792 N/A ARG 301.A NH2 ASP 84.A OD2 no hydrogen 2.812 N/A VAL 302.A N VAL 298.A O no hydrogen 3.260 N/A LEU 303.A N VAL 299.A O no hydrogen 3.170 N/A GLU 304.A N LYS 300.A O no hydrogen 2.838 N/A SER 307.A OG THR 407.A OG1 no hydrogen 2.562 N/A VAL 308.A N ILE 133.A O no hydrogen 3.279 N/A VAL 309.A N GLU 405.A O no hydrogen 3.077 N/A GLY 311.A N VAL 403.A O no hydrogen 3.293 N/A ALA 314.A N GLY 311.A O no hydrogen 3.276 N/A GLU 316.A N GLU 316.A OE1 no hydrogen 2.578 N/A ALA 317.A N GLY 313.A O no hydrogen 3.112 N/A ALA 318.A N ALA 314.A O no hydrogen 3.221 N/A LEU 319.A N VAL 315.A O no hydrogen 2.967 N/A SER 320.A N GLU 316.A O no hydrogen 3.196 N/A ILE 321.A N ALA 318.A O no hydrogen 3.113 N/A TYR 322.A N ALA 318.A O no hydrogen 3.074 N/A LEU 323.A N LEU 319.A O no hydrogen 2.963 N/A ASN 325.A N ILE 321.A O no hydrogen 3.183 N/A TYR 326.A N TYR 322.A O no hydrogen 2.803 N/A ALA 327.A N LEU 323.A O no hydrogen 3.074 N/A THR 328.A OG1 ASN 325.A O no hydrogen 2.736 N/A SER 329.A N TYR 326.A O no hydrogen 3.088 N/A SER 329.A OG TYR 326.A O no hydrogen 2.633 N/A MET 330.A N ALA 327.A O no hydrogen 3.226 N/A SER 332.A OG GLY 331.A O no hydrogen 2.390 N/A ARG 333.A NH2 LYS 107.A O no hydrogen 3.541 N/A GLU 334.A N GLY 331.A O no hydrogen 3.421 N/A ILE 338.A N GLU 334.A O no hydrogen 3.042 N/A ALA 339.A N GLN 335.A O no hydrogen 2.638 N/A GLU 340.A N LEU 336.A O no hydrogen 2.967 N/A PHE 341.A N ALA 337.A O no hydrogen 3.112 N/A ALA 342.A N ILE 338.A O no hydrogen 3.176 N/A ALA 342.A N ALA 339.A O no hydrogen 3.223 N/A ARG 343.A N ALA 339.A O no hydrogen 3.417 N/A SER 344.A N GLU 340.A O no hydrogen 3.149 N/A SER 344.A OG PHE 341.A O no hydrogen 2.743 N/A LEU 345.A N ALA 342.A O no hydrogen 3.305 N/A LEU 346.A N ARG 343.A O no hydrogen 3.188 N/A VAL 347.A N SER 344.A O no hydrogen 3.322 N/A ILE 348.A N LEU 345.A O no hydrogen 3.293 N/A ASN 350.A N LEU 346.A O no hydrogen 2.933 N/A THR 351.A N VAL 347.A O no hydrogen 2.538 N/A THR 351.A OG1 VAL 347.A O no hydrogen 2.627 N/A LEU 352.A N ILE 348.A O no hydrogen 2.944 N/A ALA 353.A N PRO 349.A O no hydrogen 3.119 N/A VAL 354.A N ASN 350.A O no hydrogen 3.279 N/A ASN 355.A N THR 351.A O no hydrogen 3.078 N/A ASN 355.A ND2 LYS 29.A O no hydrogen 3.446 N/A ASN 355.A ND2 LEU 32.A O no hydrogen 2.660 N/A ALA 356.A N LEU 352.A O no hydrogen 3.067 N/A ALA 357.A N VAL 354.A O no hydrogen 3.038 N/A GLN 358.A N ALA 353.A O no hydrogen 3.159 N/A SER 360.A OG ASN 350.A OD1 no hydrogen 2.814 N/A ASP 362.A N ASP 359.A O no hydrogen 3.146 N/A LEU 363.A N ASP 359.A O no hydrogen 3.127 N/A VAL 364.A N SER 360.A O no hydrogen 2.919 N/A ALA 365.A N THR 361.A O no hydrogen 3.351 N/A LYS 366.A N ASP 362.A O no hydrogen 2.718 N/A LEU 367.A N LEU 363.A O no hydrogen 2.670 N/A ARG 368.A N VAL 364.A O no hydrogen 2.956 N/A ALA 369.A N ALA 365.A O no hydrogen 3.002 N/A PHE 370.A N LYS 366.A O no hydrogen 3.484 N/A HIS 371.A N LEU 367.A O no hydrogen 3.425 N/A HIS 371.A NE2 ILE 386.A O no hydrogen 3.068 N/A ASN 372.A N ARG 368.A O no hydrogen 2.876 N/A GLU 373.A N ALA 369.A O no hydrogen 3.094 N/A ALA 374.A N PHE 370.A O no hydrogen 3.230 N/A ALA 374.A N HIS 371.A O no hydrogen 3.228 N/A GLN 375.A N ASN 372.A O no hydrogen 3.119 N/A VAL 376.A N ASN 372.A O no hydrogen 3.234 N/A ASN 382.A ND2 GLU 379.A O no hydrogen 3.487 N/A LYS 384.A NZ PRO 378.A O no hydrogen 3.126 N/A TRP 385.A NE1 ASN 131.A OD1 no hydrogen 3.274 N/A GLY 387.A N ARG 396.A O no hydrogen 2.719 N/A ASP 389.A N LYS 394.A O no hydrogen 2.586 N/A SER 391.A N ASP 389.A OD1 no hydrogen 3.206 N/A SER 391.A OG ASP 389.A OD1 no hydrogen 2.751 N/A ASN 392.A N ASP 389.A OD1 no hydrogen 3.414 N/A ASN 392.A ND2 ASP 389.A OD2 no hydrogen 2.842 N/A GLY 393.A N ASP 389.A O no hydrogen 2.777 N/A LYS 394.A N ASP 389.A O no hydrogen 3.318 N/A ARG 396.A N GLY 387.A O no hydrogen 3.427 N/A ARG 396.A NE ASP 389.A OD2 no hydrogen 2.809 N/A ARG 396.A NH2 ASP 389.A OD2 no hydrogen 3.109 N/A ASN 398.A ND2 GLY 311.A O no hydrogen 2.600 N/A LYS 399.A N ASP 397.A OD1 no hydrogen 3.257 N/A GLN 400.A N ASP 397.A O no hydrogen 3.221 N/A ALA 401.A N ASP 397.A O no hydrogen 3.156 N/A GLY 402.A N ASN 398.A O no hydrogen 3.159 N/A VAL 403.A N ASN 398.A O no hydrogen 3.356 N/A GLU 405.A N VAL 309.A O no hydrogen 3.130 N/A THR 407.A N SER 307.A O no hydrogen 3.373 N/A THR 407.A OG1 SER 307.A OG no hydrogen 2.562 N/A VAL 409.A N PRO 406.A O no hydrogen 3.214 N/A LYS 410.A NZ GLU 316.A OE1 no hydrogen 3.140 N/A LYS 410.A NZ GLU 316.A OE2 no hydrogen 3.099 N/A VAL 411.A N THR 407.A O no hydrogen 3.026 N/A LYS 412.A N ILE 408.A O no hydrogen 2.883 N/A SER 413.A N VAL 409.A O no hydrogen 2.817 N/A SER 413.A OG VAL 409.A O no hydrogen 2.601 N/A SER 413.A OG LYS 410.A O no hydrogen 3.060 N/A LYS 415.A N VAL 411.A O no hydrogen 3.263 N/A PHE 416.A N LYS 412.A O no hydrogen 2.733 N/A ALA 417.A N SER 413.A O no hydrogen 3.035 N/A THR 418.A N LEU 414.A O no hydrogen 2.928 N/A THR 418.A OG1 LEU 414.A O no hydrogen 2.704 N/A GLU 419.A N LYS 415.A O no hydrogen 2.944 N/A ALA 420.A N PHE 416.A O no hydrogen 2.956 N/A ALA 421.A N ALA 417.A O no hydrogen 3.079 N/A ILE 422.A N THR 418.A O no hydrogen 2.993 N/A THR 423.A N GLU 419.A O no hydrogen 2.978 N/A THR 423.A OG1 GLU 419.A O no hydrogen 2.653 N/A ILE 424.A N ALA 420.A O no hydrogen 2.914 N/A LEU 425.A N ALA 421.A O no hydrogen 2.819 N/A ARG 426.A N ILE 422.A O no hydrogen 2.946 N/A LEU 430.A N SER 8.A O no hydrogen 2.928 N/A LEU 430.A N ASP 429.A OD1 no hydrogen 2.969 N/A LYS 432.A N ASP 6.A O no hydrogen 2.928 N/A