Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x8r_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 SER 1.A O no hydrogen 3.383 N/A VAL 6.A N LEU 2.A O no hydrogen 3.086 N/A GLN 7.A N TRP 3.A O no hydrogen 2.926 N/A GLN 7.A NE2 GLU 4.A O no hydrogen 3.519 N/A LYS 8.A N GLU 4.A O no hydrogen 2.910 N/A TRP 9.A N THR 5.A O no hydrogen 2.886 N/A ARG 10.A N VAL 6.A O no hydrogen 2.909 N/A GLU 11.A N GLN 7.A O no hydrogen 2.912 N/A TYR 12.A N LYS 8.A O no hydrogen 2.881 N/A ARG 13.A N TRP 9.A O no hydrogen 2.916 N/A ARG 14.A N ARG 10.A O no hydrogen 2.903 N/A GLN 15.A N GLU 11.A O no hydrogen 2.894 N/A CYS 16.A N TYR 12.A O no hydrogen 2.904 N/A CYS 16.A SG TYR 12.A O no hydrogen 3.233 N/A GLN 17.A N ARG 13.A O no hydrogen 2.900 N/A ARG 18.A N ARG 14.A O no hydrogen 2.902 N/A SER 19.A N GLN 15.A O no hydrogen 2.898 N/A LEU 20.A N CYS 16.A O no hydrogen 2.903 N/A THR 21.A N GLN 17.A O no hydrogen 2.902 N/A THR 21.A OG1 GLN 17.A O no hydrogen 2.433 N/A GLU 22.A N ARG 18.A O no hydrogen 2.716 N/A ASP 23.A N ARG 18.A O no hydrogen 3.057 N/A LEU 29.A N PRO 25.A O no hydrogen 3.042 N/A LEU 30.A N GLU 26.A O no hydrogen 2.912 N/A PHE 31.A N GLU 27.A O no hydrogen 2.913 N/A LEU 32.A N GLN 28.A O no hydrogen 2.914 N/A TYR 33.A N LEU 29.A O no hydrogen 2.902 N/A ILE 34.A N LEU 30.A O no hydrogen 2.904 N/A ILE 35.A N PHE 31.A O no hydrogen 2.964 N/A TYR 36.A N LEU 32.A O no hydrogen 3.000 N/A THR 37.A N TYR 33.A O no hydrogen 2.928 N/A THR 37.A OG1 TYR 33.A O no hydrogen 2.551 N/A VAL 38.A N ILE 34.A O no hydrogen 2.880 N/A GLY 39.A N ILE 35.A O no hydrogen 2.944 N/A TYR 40.A N TYR 36.A O no hydrogen 2.923 N/A ALA 41.A N THR 37.A O no hydrogen 2.874 N/A LEU 42.A N VAL 38.A O no hydrogen 2.917 N/A SER 43.A N GLY 39.A O no hydrogen 2.891 N/A SER 43.A OG GLY 39.A O no hydrogen 2.723 N/A SER 43.A OG SER 267.A O no hydrogen 2.512 N/A PHE 44.A N TYR 40.A O no hydrogen 2.835 N/A SER 45.A N ALA 41.A O no hydrogen 2.993 N/A SER 45.A OG LEU 42.A O no hydrogen 2.930 N/A ALA 46.A N LEU 42.A O no hydrogen 2.922 N/A LEU 47.A N SER 43.A O no hydrogen 2.852 N/A VAL 48.A N PHE 44.A O no hydrogen 2.940 N/A ILE 49.A N SER 45.A O no hydrogen 3.002 N/A ALA 50.A N ALA 46.A O no hydrogen 2.858 N/A SER 51.A N LEU 47.A O no hydrogen 2.854 N/A SER 51.A OG LEU 47.A O no hydrogen 3.230 N/A ALA 52.A N VAL 48.A O no hydrogen 2.951 N/A ILE 53.A N ILE 49.A O no hydrogen 2.952 N/A LEU 54.A N ALA 50.A O no hydrogen 2.921 N/A LEU 55.A N SER 51.A O no hydrogen 2.907 N/A GLY 56.A N ALA 52.A O no hydrogen 2.898 N/A GLY 56.A N ILE 53.A O no hydrogen 3.132 N/A PHE 57.A N ILE 53.A O no hydrogen 3.026 N/A HIS 59.A ND1 GLU 287.A OE2 no hydrogen 2.212 N/A CYS 62.A SG LEU 60.A O no hydrogen 3.981 N/A ASN 65.A ND2 LEU 54.A O no hydrogen 3.551 N/A ASN 65.A ND2 LEU 60.A O no hydrogen 2.365 N/A TYR 66.A N CYS 62.A O no hydrogen 2.962 N/A ILE 67.A N THR 63.A O no hydrogen 2.941 N/A HIS 68.A N ARG 64.A O no hydrogen 2.877 N/A LEU 69.A N ASN 65.A O no hydrogen 2.888 N/A ASN 70.A N TYR 66.A O no hydrogen 2.951 N/A ASN 70.A ND2 TYR 66.A O no hydrogen 3.118 N/A LEU 71.A N ILE 67.A O no hydrogen 2.902 N/A PHE 72.A N HIS 68.A O no hydrogen 2.866 N/A ALA 73.A N LEU 69.A O no hydrogen 2.914 N/A SER 74.A N ASN 70.A O no hydrogen 2.927 N/A PHE 75.A N LEU 71.A O no hydrogen 2.934 N/A ILE 76.A N PHE 72.A O no hydrogen 2.897 N/A LEU 77.A N ALA 73.A O no hydrogen 2.890 N/A ARG 78.A N SER 74.A O no hydrogen 2.961 N/A ARG 78.A NH1 ASN 128.A OD1 no hydrogen 3.461 N/A ALA 79.A N PHE 75.A O no hydrogen 2.938 N/A LEU 80.A N ILE 76.A O no hydrogen 2.872 N/A SER 81.A N LEU 77.A O no hydrogen 2.866 N/A VAL 82.A N ARG 78.A O no hydrogen 3.001 N/A PHE 83.A N ALA 79.A O no hydrogen 2.911 N/A ILE 84.A N LEU 80.A O no hydrogen 2.873 N/A LYS 85.A N SER 81.A O no hydrogen 2.933 N/A LYS 85.A NZ TYR 36.A OH no hydrogen 3.531 N/A ASP 86.A N VAL 82.A O no hydrogen 2.928 N/A ALA 87.A N PHE 83.A O no hydrogen 2.907 N/A ALA 88.A N ILE 84.A O no hydrogen 2.879 N/A LEU 89.A N LYS 85.A O no hydrogen 2.964 N/A LYS 90.A NZ TYR 33.A OH no hydrogen 3.167 N/A TRP 91.A N ALA 87.A O no hydrogen 2.891 N/A MET 92.A N ALA 88.A O no hydrogen 2.914 N/A SER 94.A N LYS 90.A O no hydrogen 2.901 N/A THR 95.A N TRP 91.A O no hydrogen 2.907 N/A THR 95.A OG1 TRP 91.A O no hydrogen 3.022 N/A ALA 96.A N MET 92.A O no hydrogen 2.795 N/A GLN 98.A N GLN 101.A OE1 no hydrogen 3.069 N/A TRP 102.A N GLN 99.A O no hydrogen 3.104 N/A GLY 104.A N ASP 103.A OD1 no hydrogen 2.624 N/A LEU 106.A N TRP 102.A O no hydrogen 2.971 N/A SER 107.A N ASP 103.A O no hydrogen 2.944 N/A TYR 108.A N GLY 104.A O no hydrogen 2.805 N/A GLN 109.A N LEU 105.A O no hydrogen 2.611 N/A ASP 110.A N LEU 106.A O no hydrogen 2.757 N/A SER 111.A OG TYR 108.A O no hydrogen 2.990 N/A ARG 115.A NH1 ASP 110.A O no hydrogen 3.079 N/A ARG 115.A NH2 ASP 181.A O no hydrogen 2.398 N/A LEU 116.A N LEU 112.A O no hydrogen 2.909 N/A VAL 117.A N SER 113.A O no hydrogen 2.906 N/A PHE 118.A N CYS 114.A O no hydrogen 2.939 N/A LEU 119.A N ARG 115.A O no hydrogen 2.904 N/A LEU 120.A N LEU 116.A O no hydrogen 2.922 N/A MET 121.A N VAL 117.A O no hydrogen 2.904 N/A GLN 122.A N PHE 118.A O no hydrogen 2.955 N/A TYR 123.A N LEU 119.A O no hydrogen 2.915 N/A TYR 123.A OH TRP 162.A O no hydrogen 2.470 N/A CYS 124.A N LEU 120.A O no hydrogen 2.912 N/A CYS 124.A SG LEU 77.A O no hydrogen 3.737 N/A CYS 124.A SG LEU 120.A O no hydrogen 3.198 N/A VAL 125.A N MET 121.A O no hydrogen 3.012 N/A ALA 126.A N GLN 122.A O no hydrogen 2.960 N/A ALA 127.A N TYR 123.A O no hydrogen 2.838 N/A ASN 128.A N CYS 124.A O no hydrogen 2.978 N/A TYR 129.A N VAL 125.A O no hydrogen 3.052 N/A TYR 129.A OH GLU 247.A OE1 no hydrogen 3.393 N/A TYR 129.A OH GLU 247.A OE2 no hydrogen 3.323 N/A TYR 130.A N ALA 126.A O no hydrogen 2.918 N/A TYR 130.A OH PRO 200.A O no hydrogen 2.796 N/A TRP 131.A N ALA 127.A O no hydrogen 2.896 N/A LEU 132.A N ASN 128.A O no hydrogen 3.005 N/A LEU 133.A N TYR 129.A O no hydrogen 2.977 N/A VAL 134.A N TYR 130.A O no hydrogen 2.888 N/A GLU 135.A N TRP 131.A O no hydrogen 2.933 N/A GLY 136.A N LEU 132.A O no hydrogen 3.017 N/A VAL 137.A N LEU 133.A O no hydrogen 2.905 N/A TYR 138.A N VAL 134.A O no hydrogen 2.898 N/A LEU 139.A N GLU 135.A O no hydrogen 3.036 N/A TYR 140.A N GLY 136.A O no hydrogen 2.932 N/A THR 141.A N VAL 137.A O no hydrogen 2.917 N/A THR 141.A OG1 VAL 137.A O no hydrogen 3.239 N/A THR 141.A OG1 TYR 138.A O no hydrogen 2.936 N/A THR 141.A OG1 TYR 157.A OH no hydrogen 3.360 N/A LEU 142.A N TYR 138.A O no hydrogen 2.925 N/A LEU 143.A N LEU 139.A O no hydrogen 2.995 N/A ALA 144.A N TYR 140.A O no hydrogen 2.845 N/A ARG 155.A N GLN 151.A O no hydrogen 3.488 N/A TYR 157.A N ILE 153.A O no hydrogen 2.889 N/A TYR 157.A OH THR 141.A OG1 no hydrogen 3.360 N/A VAL 158.A N PHE 154.A O no hydrogen 2.897 N/A SER 159.A N ARG 155.A O no hydrogen 2.890 N/A SER 159.A OG LEU 156.A O no hydrogen 2.692 N/A ILE 160.A N LEU 156.A O no hydrogen 2.915 N/A TRP 162.A NE1 ASN 70.A OD1 no hydrogen 2.662 N/A GLY 163.A N SER 159.A O no hydrogen 2.780 N/A VAL 164.A N SER 159.A O no hydrogen 3.203 N/A LEU 167.A N VAL 164.A O no hydrogen 2.930 N/A PHE 168.A N PRO 165.A O no hydrogen 2.933 N/A VAL 169.A N PRO 165.A O no hydrogen 2.747 N/A TRP 172.A N VAL 169.A O no hydrogen 3.020 N/A GLY 173.A N VAL 169.A O no hydrogen 3.190 N/A ILE 174.A N VAL 170.A O no hydrogen 3.074 N/A VAL 175.A N PRO 171.A O no hydrogen 3.235 N/A LYS 176.A N TRP 172.A O no hydrogen 2.863 N/A LYS 176.A NZ GLU 180.A OE1 no hydrogen 2.761 N/A TYR 177.A N GLY 173.A O no hydrogen 2.470 N/A LEU 178.A N ILE 174.A O no hydrogen 2.979 N/A LEU 178.A N VAL 175.A O no hydrogen 2.946 N/A GLU 180.A N LYS 176.A O no hydrogen 3.111 N/A ASP 181.A N LYS 176.A O no hydrogen 2.960 N/A TRP 185.A N GLU 182.A O no hydrogen 3.274 N/A THR 186.A N GLY 183.A O no hydrogen 2.974 N/A THR 186.A OG1 GLY 183.A O no hydrogen 3.371 N/A THR 186.A OG1 CYS 184.A O no hydrogen 3.351 N/A LEU 195.A N MET 191.A O no hydrogen 2.900 N/A ILE 196.A N ASN 192.A O no hydrogen 2.929 N/A ILE 197.A N TRP 194.A O no hydrogen 3.275 N/A ARG 198.A N TRP 194.A O no hydrogen 2.914 N/A ARG 198.A N LEU 195.A O no hydrogen 2.928 N/A LEU 199.A N LEU 195.A O no hydrogen 2.910 N/A LEU 202.A N ARG 198.A O no hydrogen 3.090 N/A PHE 203.A N LEU 199.A O no hydrogen 2.888 N/A ALA 204.A N PRO 200.A O no hydrogen 3.424 N/A ILE 205.A N ILE 201.A O no hydrogen 2.976 N/A GLY 206.A N LEU 202.A O no hydrogen 2.881 N/A VAL 207.A N PHE 203.A O no hydrogen 2.943 N/A ASN 208.A N ALA 204.A O no hydrogen 2.930 N/A PHE 209.A N ILE 205.A O no hydrogen 2.980 N/A LEU 210.A N GLY 206.A O no hydrogen 2.979 N/A ILE 211.A N VAL 207.A O no hydrogen 2.945 N/A PHE 212.A N ASN 208.A O no hydrogen 2.880 N/A VAL 213.A N PHE 209.A O no hydrogen 2.977 N/A ARG 214.A N LEU 210.A O no hydrogen 2.984 N/A VAL 215.A N ILE 211.A O no hydrogen 2.905 N/A ILE 216.A N PHE 212.A O no hydrogen 2.954 N/A CYS 217.A N VAL 213.A O no hydrogen 2.941 N/A CYS 217.A SG VAL 213.A O no hydrogen 3.288 N/A ILE 218.A N ARG 214.A O no hydrogen 2.961 N/A VAL 219.A N VAL 215.A O no hydrogen 2.931 N/A VAL 220.A N ILE 216.A O no hydrogen 2.890 N/A SER 221.A N CYS 217.A O no hydrogen 2.946 N/A SER 221.A OG CYS 217.A O no hydrogen 3.504 N/A LYS 222.A N ILE 218.A O no hydrogen 2.955 N/A LEU 223.A N VAL 219.A O no hydrogen 2.918 N/A LYS 224.A N VAL 220.A O no hydrogen 2.875 N/A ALA 225.A N SER 221.A O no hydrogen 2.950 N/A ASN 226.A N LYS 222.A O no hydrogen 3.222 N/A ARG 231.A N ASP 227.A O no hydrogen 3.258 N/A ARG 231.A NE ARG 231.A O no hydrogen 3.010 N/A LEU 232.A N ILE 228.A O no hydrogen 2.894 N/A ALA 233.A N LYS 229.A O no hydrogen 2.905 N/A LYS 234.A N CYS 230.A O no hydrogen 2.905 N/A SER 235.A N ARG 231.A O no hydrogen 2.917 N/A SER 235.A OG ARG 231.A O no hydrogen 3.337 N/A SER 235.A OG LEU 232.A O no hydrogen 2.868 N/A THR 236.A N LEU 232.A O no hydrogen 2.922 N/A THR 236.A OG1 LEU 232.A O no hydrogen 2.569 N/A LEU 237.A N ALA 233.A O no hydrogen 2.915 N/A THR 238.A N LYS 234.A O no hydrogen 2.915 N/A THR 238.A OG1 LYS 234.A O no hydrogen 2.937 N/A LEU 239.A N SER 235.A O no hydrogen 2.916 N/A ILE 240.A N THR 236.A O no hydrogen 2.974 N/A LEU 243.A N ILE 240.A O no hydrogen 3.320 N/A GLY 244.A N ILE 240.A O no hydrogen 2.961 N/A HIS 246.A NE2 GLN 269.A OE1 no hydrogen 2.939 N/A VAL 248.A N THR 245.A O no hydrogen 2.931 N/A ILE 249.A N HIS 246.A O no hydrogen 2.923 N/A PHE 250.A N GLU 247.A O no hydrogen 2.910 N/A ILE 257.A N THR 253.A O no hydrogen 3.227 N/A LYS 258.A N LEU 254.A O no hydrogen 2.927 N/A LEU 259.A N ARG 255.A O no hydrogen 2.881 N/A PHE 260.A N PHE 256.A O no hydrogen 2.899 N/A THR 261.A N ILE 257.A O no hydrogen 2.939 N/A THR 261.A OG1 ILE 257.A O no hydrogen 3.091 N/A THR 261.A OG1 LYS 258.A O no hydrogen 2.714 N/A GLU 262.A N LYS 258.A O no hydrogen 2.897 N/A LEU 263.A N LEU 259.A O no hydrogen 2.908 N/A SER 264.A N PHE 260.A O no hydrogen 2.958 N/A SER 264.A OG PHE 260.A O no hydrogen 2.926 N/A PHE 265.A N THR 261.A O no hydrogen 2.942 N/A THR 266.A N GLU 262.A O no hydrogen 2.911 N/A THR 266.A OG1 GLU 262.A O no hydrogen 2.561 N/A SER 267.A N LEU 263.A O no hydrogen 2.892 N/A SER 267.A OG LEU 263.A O no hydrogen 2.532 N/A PHE 268.A N SER 264.A O no hydrogen 2.999 N/A GLN 269.A N THR 266.A O no hydrogen 3.325 N/A GLN 269.A NE2 PRO 241.A O no hydrogen 3.012 N/A LEU 271.A N SER 43.A OG no hydrogen 3.246 N/A MET 272.A N PHE 268.A O no hydrogen 2.985 N/A VAL 273.A N GLN 269.A O no hydrogen 2.873 N/A ALA 274.A N GLY 270.A O no hydrogen 2.952 N/A ILE 275.A N LEU 271.A O no hydrogen 2.932 N/A LEU 276.A N MET 272.A O no hydrogen 2.902 N/A TYR 277.A N VAL 273.A O no hydrogen 2.948 N/A TYR 277.A OH THR 238.A O no hydrogen 2.533 N/A CYS 278.A N ALA 274.A O no hydrogen 2.901 N/A CYS 278.A SG ALA 50.A O no hydrogen 3.614 N/A PHE 279.A N ALA 274.A O no hydrogen 3.357 N/A PHE 279.A N ILE 275.A O no hydrogen 3.139 N/A VAL 280.A N ILE 275.A O no hydrogen 2.948 N/A GLU 283.A N ASN 281.A OD1 no hydrogen 3.367 N/A GLN 285.A N ASN 281.A O no hydrogen 3.028 N/A GLN 285.A NE2 PHE 279.A O no hydrogen 3.281 N/A LEU 286.A N ASN 282.A O no hydrogen 2.918 N/A GLU 287.A N GLU 283.A O no hydrogen 2.912 N/A PHE 288.A N VAL 284.A O no hydrogen 2.895 N/A ARG 289.A N GLN 285.A O no hydrogen 2.899 N/A LYS 290.A N LEU 286.A O no hydrogen 2.946 N/A SER 291.A N GLU 287.A O no hydrogen 2.890 N/A TRP 292.A N PHE 288.A O no hydrogen 2.895 N/A GLU 293.A N ARG 289.A O no hydrogen 2.921 N/A ARG 294.A N LYS 290.A O no hydrogen 2.949 N/A TRP 295.A N SER 291.A O no hydrogen 2.890 N/A ARG 296.A N TRP 292.A O no hydrogen 2.879 N/A LEU 297.A N GLU 293.A O no hydrogen 2.915 N/A