Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7x8s_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 4.A NE2 GLU 1.A O no hydrogen 3.278 N/A ARG 6.A N LEU 2.A O no hydrogen 2.900 N/A GLN 7.A N ASP 3.A O no hydrogen 2.934 N/A GLN 7.A NE2 ASP 3.A OD2 no hydrogen 2.385 N/A GLU 8.A N GLN 4.A O no hydrogen 2.904 N/A ALA 9.A N LEU 5.A O no hydrogen 2.896 N/A GLU 10.A N ARG 6.A O no hydrogen 2.912 N/A GLN 11.A N GLN 7.A O no hydrogen 2.878 N/A LEU 12.A N GLU 8.A O no hydrogen 2.924 N/A LYS 13.A N ALA 9.A O no hydrogen 2.906 N/A ASN 14.A N GLU 10.A O no hydrogen 2.891 N/A GLN 15.A N GLN 11.A O no hydrogen 2.883 N/A ILE 16.A N LEU 12.A O no hydrogen 2.934 N/A ARG 17.A N LYS 13.A O no hydrogen 2.893 N/A ARG 17.A NH1 ASN 14.A OD1 no hydrogen 2.556 N/A ARG 17.A NH2 ASP 18.A OD1 no hydrogen 3.541 N/A ARG 17.A NH2 ASP 18.A OD2 no hydrogen 3.503 N/A ASP 18.A N ASN 14.A O no hydrogen 2.882 N/A ALA 19.A N GLN 15.A O no hydrogen 2.913 N/A ARG 20.A N ILE 16.A O no hydrogen 2.902 N/A ARG 20.A NH2 THR 219.A O no hydrogen 2.902 N/A LYS 21.A N ARG 17.A O no hydrogen 2.895 N/A ALA 22.A N ASP 18.A O no hydrogen 2.891 N/A CYS 23.A N ALA 19.A O no hydrogen 2.919 N/A CYS 23.A SG ALA 19.A O no hydrogen 3.697 N/A ALA 24.A N LYS 21.A O no hydrogen 3.070 N/A ASP 25.A N CYS 23.A O no hydrogen 2.950 N/A THR 27.A N GLN 30.A OE1 no hydrogen 3.399 N/A THR 27.A OG1 SER 29.A OG no hydrogen 3.023 N/A THR 27.A OG1 GLN 30.A OE1 no hydrogen 3.089 N/A SER 29.A OG THR 27.A OG1 no hydrogen 3.023 N/A GLN 30.A N THR 27.A O no hydrogen 3.307 N/A THR 32.A N LEU 28.A O no hydrogen 3.109 N/A THR 32.A OG1 LEU 28.A O no hydrogen 2.549 N/A THR 32.A OG1 SER 29.A O no hydrogen 3.451 N/A ASN 33.A N GLN 30.A O no hydrogen 3.284 N/A ILE 35.A N THR 32.A O no hydrogen 3.339 N/A ILE 41.A N ALA 303.A O no hydrogen 2.531 N/A ARG 46.A N ILE 336.A O no hydrogen 2.894 N/A ARG 47.A NE SER 82.A O no hydrogen 3.282 N/A ARG 47.A NH2 TYR 83.A O no hydrogen 3.004 N/A LEU 49.A N LEU 334.A O no hydrogen 2.933 N/A HIS 52.A NE2 SER 70.A OG no hydrogen 2.338 N/A HIS 60.A N VAL 69.A O no hydrogen 2.900 N/A TRP 61.A NE1 GLY 317.A O no hydrogen 2.919 N/A GLY 62.A N LEU 67.A O no hydrogen 2.812 N/A THR 63.A OG1 PRO 105.A O no hydrogen 3.200 N/A SER 65.A N GLY 62.A O no hydrogen 3.452 N/A SER 65.A OG ASP 321.A OD1 no hydrogen 2.208 N/A VAL 69.A N HIS 60.A O no hydrogen 2.905 N/A SER 70.A N ILE 78.A O no hydrogen 2.901 N/A SER 70.A OG HIS 52.A NE2 no hydrogen 2.338 N/A ALA 71.A N ALA 58.A O no hydrogen 2.921 N/A SER 72.A N LYS 76.A O no hydrogen 2.919 N/A SER 72.A OG ALA 54.A O no hydrogen 3.423 N/A SER 72.A OG LYS 55.A O no hydrogen 3.222 N/A SER 72.A OG ASP 74.A OD1 no hydrogen 2.699 N/A GLN 73.A N LYS 55.A O no hydrogen 2.934 N/A GLY 75.A N SER 72.A O no hydrogen 3.060 N/A LEU 77.A N ILE 91.A O no hydrogen 2.919 N/A ILE 78.A N SER 70.A O no hydrogen 2.934 N/A ILE 79.A N HIS 89.A O no hydrogen 2.927 N/A TRP 80.A N LEU 68.A O no hydrogen 2.913 N/A TRP 80.A NE1 SER 70.A OG no hydrogen 3.033 N/A ASP 81.A N ASN 86.A O no hydrogen 2.936 N/A SER 82.A N ARG 66.A O no hydrogen 2.989 N/A SER 82.A OG ARG 66.A O no hydrogen 3.184 N/A THR 84.A N ASP 81.A O no hydrogen 3.182 N/A THR 84.A OG1 ASP 81.A OD2 no hydrogen 2.690 N/A THR 85.A N ASP 81.A O no hydrogen 2.662 N/A LYS 87.A NZ ARG 50.A O no hydrogen 3.129 N/A VAL 88.A N ILE 79.A O no hydrogen 2.818 N/A ILE 91.A N LEU 77.A O no hydrogen 2.860 N/A LEU 93.A N GLY 75.A O no hydrogen 3.225 N/A MET 99.A N GLY 113.A O no hydrogen 2.893 N/A THR 100.A N GLY 113.A O no hydrogen 3.331 N/A CYS 101.A SG VAL 69.A O no hydrogen 3.861 N/A ALA 102.A N ALA 111.A O no hydrogen 3.233 N/A ALA 104.A N TYR 109.A O no hydrogen 2.901 N/A SER 106.A OG ASP 152.A OD1 no hydrogen 2.692 N/A SER 106.A OG ASP 152.A OD2 no hydrogen 3.175 N/A GLY 107.A N ALA 104.A O no hydrogen 2.784 N/A ASN 108.A N SER 106.A OG no hydrogen 3.132 N/A VAL 110.A N TYR 122.A O no hydrogen 2.926 N/A CYS 112.A N SER 120.A O no hydrogen 2.951 N/A CYS 112.A SG SER 120.A O no hydrogen 3.889 N/A CYS 112.A SG TYR 122.A OH no hydrogen 3.671 N/A LEU 115.A N TRP 97.A O no hydrogen 3.110 N/A ASN 117.A N GLY 114.A O no hydrogen 3.020 N/A CYS 119.A SG CYS 112.A O no hydrogen 3.136 N/A ILE 121.A N ARG 135.A O no hydrogen 2.955 N/A TYR 122.A N VAL 110.A O no hydrogen 2.878 N/A LEU 124.A N ASN 108.A O no hydrogen 2.914 N/A LYS 125.A N ASN 123.A OD1 no hydrogen 3.174 N/A THR 126.A OG1 ASN 130.A O no hydrogen 2.312 N/A GLY 129.A N THR 126.A OG1 no hydrogen 3.238 N/A SER 134.A N ILE 121.A O no hydrogen 2.902 N/A SER 134.A OG ILE 121.A O no hydrogen 3.280 N/A ARG 135.A NH1 GLU 170.A O no hydrogen 2.840 N/A LEU 137.A N CYS 119.A O no hydrogen 2.878 N/A HIS 140.A NE2 THR 157.A OG1 no hydrogen 2.751 N/A THR 141.A OG1 ASP 161.A OD2 no hydrogen 2.744 N/A TYR 143.A OH ASP 184.A OD2 no hydrogen 3.078 N/A LEU 144.A N GLY 114.A O no hydrogen 3.141 N/A SER 145.A N SER 158.A O no hydrogen 2.925 N/A SER 145.A OG SER 158.A O no hydrogen 3.295 N/A SER 145.A OG SER 158.A OG no hydrogen 3.308 N/A SER 145.A OG VAL 185.A O no hydrogen 2.527 N/A SER 145.A OG MET 186.A O no hydrogen 3.483 N/A CYS 146.A N SER 158.A O no hydrogen 3.275 N/A CYS 146.A SG LEU 188.A O no hydrogen 4.006 N/A ARG 148.A N VAL 156.A O no hydrogen 3.004 N/A ARG 148.A NH1 CYS 101.A O no hydrogen 2.836 N/A LEU 150.A N GLN 154.A O no hydrogen 2.929 N/A ASP 151.A N GLN 154.A O no hydrogen 3.457 N/A ASN 153.A N ASP 151.A OD1 no hydrogen 2.958 N/A GLN 154.A N ASP 151.A OD1 no hydrogen 2.474 N/A GLN 154.A NE2 ASP 151.A OD2 no hydrogen 2.602 N/A ILE 155.A N TRP 167.A O no hydrogen 2.960 N/A VAL 156.A N ARG 148.A O no hydrogen 3.312 N/A THR 157.A N ALA 165.A O no hydrogen 2.879 N/A THR 157.A OG1 HIS 140.A NE2 no hydrogen 2.751 N/A SER 158.A N CYS 146.A O no hydrogen 3.002 N/A SER 158.A OG SER 145.A OG no hydrogen 3.308 N/A SER 159.A OG HIS 140.A ND1 no hydrogen 2.788 N/A SER 159.A OG ASP 161.A OD1 no hydrogen 2.155 N/A SER 159.A OG THR 163.A O no hydrogen 2.857 N/A GLY 160.A N TYR 143.A O no hydrogen 2.687 N/A THR 162.A OG1 ASP 161.A O no hydrogen 2.301 N/A THR 163.A OG1 ASP 161.A OD1 no hydrogen 3.292 N/A THR 163.A OG1 ASP 161.A OD2 no hydrogen 3.362 N/A CYS 164.A N PHE 178.A O no hydrogen 2.939 N/A ALA 165.A N THR 157.A O no hydrogen 2.901 N/A LEU 166.A N THR 176.A O no hydrogen 2.851 N/A TRP 167.A N ILE 155.A O no hydrogen 2.882 N/A TRP 167.A NE1 THR 157.A OG1 no hydrogen 2.853 N/A ILE 169.A N ASN 153.A O no hydrogen 2.737 N/A THR 171.A OG1 ASP 168.A O no hydrogen 3.092 N/A THR 171.A OG1 GLN 173.A O no hydrogen 3.452 N/A GLY 172.A N ASP 168.A O no hydrogen 2.816 N/A GLN 173.A N THR 171.A OG1 no hydrogen 3.269 N/A THR 175.A N LEU 166.A O no hydrogen 2.820 N/A THR 176.A N LEU 166.A O no hydrogen 2.979 N/A THR 177.A OG1 GLN 174.A OE1 no hydrogen 2.422 N/A PHE 178.A N CYS 164.A O no hydrogen 2.874 N/A HIS 181.A NE2 SER 199.A OG no hydrogen 2.393 N/A THR 182.A OG1 ASP 203.A OD2 no hydrogen 2.966 N/A MET 186.A N GLY 200.A O no hydrogen 2.913 N/A SER 189.A N VAL 198.A O no hydrogen 3.160 N/A SER 189.A OG LEU 190.A O no hydrogen 3.541 N/A ALA 191.A N LEU 196.A O no hydrogen 3.182 N/A THR 194.A N ALA 191.A O no hydrogen 2.958 N/A THR 194.A OG1 ASP 193.A O no hydrogen 2.536 N/A PHE 197.A N TRP 209.A O no hydrogen 2.945 N/A VAL 198.A N SER 189.A O no hydrogen 3.307 N/A SER 199.A N LYS 207.A O no hydrogen 2.909 N/A SER 199.A OG HIS 181.A NE2 no hydrogen 2.393 N/A GLY 200.A N SER 187.A O no hydrogen 3.335 N/A CYS 202.A N ASP 184.A O no hydrogen 3.049 N/A CYS 202.A SG ASP 184.A O no hydrogen 3.763 N/A CYS 202.A SG ASP 184.A OD1 no hydrogen 2.987 N/A SER 205.A OG ASP 203.A OD1 no hydrogen 3.237 N/A SER 205.A OG ASP 203.A OD2 no hydrogen 2.893 N/A ALA 206.A N PHE 220.A O no hydrogen 2.911 N/A LYS 207.A N SER 199.A O no hydrogen 2.921 N/A LEU 208.A N GLN 218.A O no hydrogen 2.899 N/A TRP 209.A N PHE 197.A O no hydrogen 2.871 N/A TRP 209.A NE1 SER 199.A OG no hydrogen 2.457 N/A ARG 212.A N ASP 210.A OD1 no hydrogen 3.287 N/A GLY 214.A N ASP 210.A O no hydrogen 2.829 N/A CYS 216.A SG LEU 208.A O no hydrogen 3.406 N/A CYS 216.A SG GLN 218.A O no hydrogen 3.350 N/A ARG 217.A N LEU 208.A O no hydrogen 2.706 N/A PHE 220.A N ALA 206.A O no hydrogen 2.912 N/A HIS 223.A NE2 THR 241.A O no hydrogen 3.188 N/A HIS 223.A NE2 THR 241.A OG1 no hydrogen 2.301 N/A GLU 224.A N ASP 245.A OD2 no hydrogen 3.485 N/A ASP 226.A N SER 225.A OG no hydrogen 2.541 N/A ILE 227.A N ALA 201.A O no hydrogen 3.270 N/A ASN 228.A N GLY 242.A O no hydrogen 2.906 N/A ALA 229.A N GLY 242.A O no hydrogen 3.297 N/A CYS 231.A N ALA 240.A O no hydrogen 3.305 N/A CYS 231.A SG PHE 232.A O no hydrogen 3.305 N/A PHE 232.A N SER 189.A OG no hydrogen 3.210 N/A PHE 233.A N ALA 238.A O no hydrogen 2.722 N/A GLY 236.A N PHE 233.A O no hydrogen 2.909 N/A ASN 237.A N ASN 235.A OD1 no hydrogen 2.913 N/A PHE 239.A N PHE 251.A O no hydrogen 2.925 N/A ALA 240.A N CYS 231.A O no hydrogen 3.025 N/A THR 241.A N ARG 249.A O no hydrogen 2.880 N/A THR 241.A OG1 HIS 223.A NE2 no hydrogen 2.301 N/A GLY 242.A N ALA 229.A O no hydrogen 3.232 N/A SER 243.A N THR 247.A O no hydrogen 3.445 N/A ASP 244.A N ASP 226.A O no hydrogen 3.008 N/A THR 247.A OG1 ASP 245.A OD1 no hydrogen 3.115 N/A THR 247.A OG1 ASP 245.A OD2 no hydrogen 3.113 N/A CYS 248.A N TYR 262.A O no hydrogen 2.926 N/A ARG 249.A N THR 241.A O no hydrogen 2.927 N/A ARG 249.A NE GLU 258.A OE2 no hydrogen 3.259 N/A LEU 250.A N MET 260.A O no hydrogen 2.938 N/A PHE 251.A N PHE 239.A O no hydrogen 2.904 N/A LEU 253.A N ASN 237.A O no hydrogen 3.374 N/A ASP 256.A N ASP 252.A O no hydrogen 2.764 N/A LEU 259.A N LEU 250.A O no hydrogen 2.806 N/A TYR 262.A N CYS 248.A O no hydrogen 2.861 N/A TYR 262.A OH ALA 297.A O no hydrogen 2.484 N/A ASN 266.A N HIS 264.A ND1 no hydrogen 3.129 N/A ILE 267.A N HIS 264.A O no hydrogen 3.043 N/A ILE 271.A N SER 243.A O no hydrogen 2.931 N/A THR 272.A N GLY 286.A O no hydrogen 3.173 N/A THR 272.A OG1 VAL 313.A O no hydrogen 2.445 N/A SER 273.A OG THR 272.A O no hydrogen 2.611 N/A SER 273.A OG SER 314.A O no hydrogen 2.723 N/A SER 275.A N LEU 284.A O no hydrogen 2.916 N/A SER 275.A OG VAL 274.A O no hydrogen 2.662 N/A SER 275.A OG LEU 316.A O no hydrogen 2.841 N/A SER 277.A N LEU 282.A O no hydrogen 2.708 N/A GLY 280.A N SER 277.A O no hydrogen 2.954 N/A LEU 283.A N TRP 295.A O no hydrogen 2.891 N/A LEU 284.A N SER 275.A O no hydrogen 2.871 N/A ALA 285.A N ASN 293.A O no hydrogen 2.929 N/A GLY 286.A N SER 273.A O no hydrogen 2.871 N/A CYS 292.A N LEU 306.A O no hydrogen 3.090 N/A ASN 293.A N ALA 285.A O no hydrogen 2.875 N/A VAL 294.A N GLY 304.A O no hydrogen 2.989 N/A TRP 295.A N LEU 283.A O no hydrogen 2.853 N/A TRP 295.A NE1 TYR 287.A OH no hydrogen 3.120 N/A ALA 297.A N ARG 281.A O no hydrogen 3.475 N/A ALA 300.A N ASP 296.A O no hydrogen 2.826 N/A ASP 301.A N ASP 296.A OD1 no hydrogen 2.610 N/A ALA 303.A N VAL 294.A O no hydrogen 2.818 N/A HIS 309.A NE2 THR 327.A OG1 no hydrogen 2.824 N/A ARG 312.A N ASN 311.A OD1 no hydrogen 2.678 N/A SER 314.A N GLY 328.A O no hydrogen 3.424 N/A SER 314.A OG ILE 56.A O no hydrogen 2.192 N/A GLY 317.A N ALA 326.A O no hydrogen 2.907 N/A THR 319.A N ALA 324.A O no hydrogen 3.287 N/A THR 319.A OG1 ALA 324.A O no hydrogen 3.553 N/A ASP 321.A N ASP 321.A OD1 no hydrogen 2.538 N/A GLY 322.A N THR 319.A O no hydrogen 3.070 N/A MET 323.A N THR 319.A OG1 no hydrogen 2.836 N/A VAL 325.A N TRP 337.A O no hydrogen 2.974 N/A ALA 326.A N GLY 317.A O no hydrogen 2.930 N/A THR 327.A N LYS 335.A O no hydrogen 2.907 N/A THR 327.A OG1 HIS 309.A NE2 no hydrogen 2.824 N/A THR 327.A OG1 LYS 335.A O no hydrogen 3.491 N/A GLY 328.A N CYS 315.A O no hydrogen 2.923 N/A SER 329.A N PHE 333.A O no hydrogen 2.981 N/A SER 329.A OG ARG 312.A O no hydrogen 2.320 N/A TRP 330.A N ARG 312.A O no hydrogen 2.800 N/A SER 332.A N SER 329.A O no hydrogen 3.174 N/A SER 332.A OG HIS 52.A O no hydrogen 3.321 N/A SER 332.A OG LEU 53.A O no hydrogen 3.418 N/A SER 332.A OG ASP 331.A O no hydrogen 2.300 N/A PHE 333.A N ASP 331.A OD1 no hydrogen 3.260 N/A LEU 334.A N LEU 49.A O no hydrogen 3.461 N/A LYS 335.A N THR 327.A O no hydrogen 2.911 N/A ILE 336.A N ARG 47.A O no hydrogen 3.108 N/A TRP 337.A N VAL 325.A O no hydrogen 2.875 N/A TRP 337.A NE1 THR 327.A OG1 no hydrogen 2.823 N/A ASN 338.A N ARG 44.A O no hydrogen 3.381 N/A