Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7xhy_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N GLU 4.A OE2 no hydrogen 2.416 N/A GLU 4.A N SER 1.A OG no hydrogen 3.351 N/A GLU 5.A N SER 1.A O no hydrogen 2.814 N/A LEU 6.A N HIS 2.A O no hydrogen 3.112 N/A GLN 7.A N MET 3.A O no hydrogen 2.875 N/A ASN 8.A N GLU 4.A O no hydrogen 2.863 N/A ASN 8.A ND2 GLU 4.A O no hydrogen 3.558 N/A LYS 9.A N GLU 5.A O no hydrogen 3.041 N/A LEU 10.A N LEU 6.A O no hydrogen 2.971 N/A GLU 11.A N GLN 7.A O no hydrogen 3.077 N/A GLU 11.A N ASN 8.A O no hydrogen 2.921 N/A VAL 13.A N LEU 10.A O no hydrogen 3.494 N/A ILE 15.A N VAL 81.A O no hydrogen 2.823 N/A ARG 17.A NE GLU 84.A OE2 no hydrogen 2.807 N/A ARG 17.A NH1 ARG 17.A O no hydrogen 3.087 N/A ARG 17.A NH2 GLU 84.A OE2 no hydrogen 3.294 N/A LEU 19.A N ASP 16.A O no hydrogen 2.952 N/A LEU 20.A N ARG 17.A O no hydrogen 3.252 N/A ILE 21.A N ASN 36.A O no hydrogen 3.139 N/A GLY 23.A N GLU 34.A O no hydrogen 2.670 N/A ARG 24.A N GLU 34.A OE2 no hydrogen 2.636 N/A LEU 26.A N VAL 32.A O no hydrogen 2.719 N/A GLY 27.A N VAL 32.A O no hydrogen 3.190 N/A SER 31.A N THR 51.A O no hydrogen 3.018 N/A VAL 32.A N GLY 27.A O no hydrogen 2.846 N/A MET 33.A N VAL 49.A O no hydrogen 2.769 N/A GLU 34.A N ARG 24.A O no hydrogen 3.133 N/A GLY 35.A N VAL 47.A O no hydrogen 2.837 N/A ASN 36.A N ILE 21.A O no hydrogen 3.014 N/A LEU 37.A N LEU 45.A O no hydrogen 2.773 N/A LYS 38.A N LEU 19.A O no hydrogen 2.804 N/A GLN 39.A N THR 43.A O no hydrogen 2.850 N/A GLY 42.A N GLN 39.A O no hydrogen 3.382 N/A THR 43.A N ASP 41.A OD1 no hydrogen 2.992 N/A THR 43.A OG1 GLN 39.A OE1 no hydrogen 3.556 N/A THR 43.A OG1 ASP 41.A OD1 no hydrogen 2.749 N/A LEU 45.A N LEU 37.A O no hydrogen 2.704 N/A LYS 46.A NZ GLU 34.A OE1 no hydrogen 2.885 N/A LYS 46.A NZ ASN 36.A OD1 no hydrogen 3.164 N/A VAL 47.A N GLY 35.A O no hydrogen 2.866 N/A ALA 48.A N LEU 97.A O no hydrogen 2.775 N/A VAL 49.A N MET 33.A O no hydrogen 2.697 N/A LYS 50.A N VAL 95.A O no hydrogen 2.907 N/A LYS 50.A NZ PHE 168.A O no hydrogen 3.274 N/A THR 51.A N SER 31.A O no hydrogen 2.925 N/A MET 52.A N PRO 93.A O no hydrogen 3.099 N/A GLN 54.A NE2 GLU 58.A OE2 no hydrogen 3.025 N/A ILE 57.A N GLN 54.A O no hydrogen 3.171 N/A GLU 58.A N GLN 54.A O no hydrogen 3.019 N/A PHE 60.A N GLU 56.A O no hydrogen 3.002 N/A LEU 61.A N ILE 57.A O no hydrogen 2.947 N/A SER 62.A N GLU 58.A O no hydrogen 2.799 N/A SER 62.A OG GLU 58.A O no hydrogen 2.914 N/A SER 62.A OG GLU 59.A O no hydrogen 3.330 N/A GLU 63.A N GLU 59.A O no hydrogen 3.006 N/A ALA 64.A N PHE 60.A O no hydrogen 3.021 N/A ALA 65.A N LEU 61.A O no hydrogen 2.833 N/A CYS 66.A N SER 62.A O no hydrogen 2.914 N/A MET 67.A N GLU 63.A O no hydrogen 3.040 N/A LYS 68.A N ALA 64.A O no hydrogen 2.906 N/A ASP 69.A N ALA 65.A O no hydrogen 3.181 N/A PHE 70.A N CYS 66.A O no hydrogen 3.219 N/A SER 71.A N TYR 139.A OH no hydrogen 2.805 N/A ASN 74.A N HIS 72.A ND1 no hydrogen 2.992 N/A ASN 74.A ND2 VAL 163.A O no hydrogen 2.970 N/A VAL 75.A N HIS 72.A O no hydrogen 3.244 N/A ILE 76.A N VAL 165.A O no hydrogen 2.852 N/A LEU 79.A N ILE 96.A O no hydrogen 2.829 N/A GLY 80.A N ILE 96.A O no hydrogen 3.459 N/A VAL 81.A N VAL 13.A O no hydrogen 2.940 N/A CYS 82.A N MET 94.A O no hydrogen 2.915 N/A CYS 82.A SG ILE 15.A O no hydrogen 3.759 N/A GLU 84.A N LYS 92.A O no hydrogen 2.971 N/A SER 86.A N ILE 90.A O no hydrogen 2.706 N/A SER 86.A OG ILE 90.A O no hydrogen 2.931 N/A GLY 89.A N SER 86.A O no hydrogen 2.780 N/A ILE 90.A N SER 86.A OG no hydrogen 2.914 N/A LYS 92.A N GLU 84.A O no hydrogen 2.510 N/A MET 94.A N CYS 82.A O no hydrogen 2.685 N/A VAL 95.A N LYS 50.A O no hydrogen 2.884 N/A ILE 96.A N GLY 80.A O no hydrogen 2.809 N/A LEU 97.A N ALA 48.A O no hydrogen 2.972 N/A PHE 99.A N LYS 46.A O no hydrogen 3.181 N/A GLY 103.A N MET 100.A O no hydrogen 2.952 N/A LEU 105.A N CYS 155.A O no hydrogen 2.631 N/A HIS 106.A N ALA 152.A O no hydrogen 3.318 N/A THR 107.A N ASP 104.A OD2 no hydrogen 3.141 N/A THR 107.A OG1 ASP 104.A OD1 no hydrogen 2.468 N/A THR 107.A OG1 ASP 104.A OD2 no hydrogen 3.282 N/A TYR 108.A N ASP 104.A O no hydrogen 3.203 N/A LEU 109.A N LEU 105.A O no hydrogen 2.991 N/A LEU 110.A N HIS 106.A O no hydrogen 3.193 N/A TYR 111.A N THR 107.A O no hydrogen 2.894 N/A SER 112.A N TYR 108.A O no hydrogen 2.956 N/A SER 112.A OG LEU 109.A O no hydrogen 2.749 N/A ARG 113.A N LEU 110.A O no hydrogen 2.847 N/A LEU 114.A N TYR 111.A O no hydrogen 2.810 N/A GLY 117.A N LEU 114.A O no hydrogen 3.098 N/A LEU 126.A N PRO 122.A O no hydrogen 3.006 N/A LEU 127.A N LEU 123.A O no hydrogen 2.890 N/A ARG 128.A N GLN 124.A O no hydrogen 3.004 N/A ARG 128.A NH2 GLN 124.A OE1 no hydrogen 3.168 N/A PHE 129.A N THR 125.A O no hydrogen 2.834 N/A MET 130.A N LEU 126.A O no hydrogen 3.392 N/A VAL 131.A N LEU 127.A O no hydrogen 2.869 N/A ASP 132.A N ARG 128.A O no hydrogen 3.151 N/A ILE 133.A N PHE 129.A O no hydrogen 3.137 N/A ALA 134.A N MET 130.A O no hydrogen 2.868 N/A LEU 135.A N VAL 131.A O no hydrogen 2.842 N/A GLY 136.A N ASP 132.A O no hydrogen 3.111 N/A MET 137.A N ILE 133.A O no hydrogen 2.996 N/A GLU 138.A N ALA 134.A O no hydrogen 2.771 N/A TYR 139.A N LEU 135.A O no hydrogen 3.024 N/A LEU 140.A N GLY 136.A O no hydrogen 2.943 N/A SER 141.A N MET 137.A O no hydrogen 2.857 N/A SER 141.A OG MET 137.A O no hydrogen 3.080 N/A SER 141.A OG GLU 138.A O no hydrogen 3.295 N/A ASN 142.A N GLU 138.A O no hydrogen 3.003 N/A ARG 143.A N LEU 140.A O no hydrogen 2.926 N/A ARG 143.A NH1 TYR 139.A O no hydrogen 3.105 N/A ASN 144.A N SER 141.A O no hydrogen 2.686 N/A PHE 145.A N LEU 140.A O no hydrogen 3.130 N/A HIS 147.A N ASP 190.A OD2 no hydrogen 2.822 N/A HIS 147.A NE2 ALA 166.A O no hydrogen 2.761 N/A ARG 148.A N ASP 190.A OD1 no hydrogen 3.115 N/A ASP 149.A N HIS 147.A ND1 no hydrogen 3.039 N/A ALA 152.A N GLU 200.A OE1 no hydrogen 2.869 N/A ARG 153.A NH2 ASP 149.A OD1 no hydrogen 2.743 N/A ASN 154.A N ALA 151.A O no hydrogen 2.995 N/A ASN 154.A ND2 ASP 149.A O no hydrogen 2.805 N/A ASN 154.A ND2 ASP 149.A OD2 no hydrogen 3.242 N/A CYS 155.A N ALA 152.A O no hydrogen 3.082 N/A CYS 155.A SG ALA 151.A O no hydrogen 3.540 N/A MET 156.A N CYS 164.A O no hydrogen 2.968 N/A LEU 157.A N GLY 103.A O no hydrogen 2.968 N/A ARG 158.A N THR 162.A O no hydrogen 2.901 N/A ARG 158.A NH1 PRO 73.A O no hydrogen 2.498 N/A ARG 158.A NH2 PRO 73.A O no hydrogen 3.079 N/A MET 161.A N ARG 158.A O no hydrogen 2.753 N/A THR 162.A N ASP 160.A OD1 no hydrogen 3.040 N/A THR 162.A OG1 ASP 160.A OD1 no hydrogen 3.031 N/A THR 162.A OG1 ASP 160.A OD2 no hydrogen 3.365 N/A VAL 163.A N ASP 132.A OD2 no hydrogen 2.962 N/A CYS 164.A N MET 156.A O no hydrogen 2.986 N/A CYS 164.A SG MET 156.A O no hydrogen 3.826 N/A VAL 165.A N ASN 74.A O no hydrogen 2.867 N/A ALA 166.A N ASN 154.A O no hydrogen 3.031 N/A PHE 168.A N ASN 154.A OD1 no hydrogen 3.028 N/A GLY 169.A N ASP 167.A OD1 no hydrogen 2.800 N/A LYS 173.A NZ PRO 208.A O no hydrogen 2.721 N/A LYS 173.A NZ TYR 209.A O no hydrogen 2.811 N/A LYS 173.A NZ VAL 212.A O no hydrogen 2.789 N/A TRP 174.A N PRO 171.A O no hydrogen 3.092 N/A TRP 174.A NE1 GLU 200.A OE1 no hydrogen 2.918 N/A ILE 175.A N VAL 172.A O no hydrogen 3.099 N/A GLU 178.A N GLU 178.A OE2 no hydrogen 2.878 N/A SER 179.A OG VAL 184.A O no hydrogen 2.597 N/A LEU 180.A N ALA 176.A O no hydrogen 3.043 N/A LEU 180.A N ILE 177.A O no hydrogen 3.132 N/A ALA 181.A N GLU 178.A O no hydrogen 3.274 N/A ASP 182.A N GLU 178.A O no hydrogen 2.920 N/A TYR 185.A OH ASP 190.A OD1 no hydrogen 3.173 N/A THR 186.A N SER 189.A OG no hydrogen 3.168 N/A LYS 188.A N THR 186.A OG1 no hydrogen 3.180 N/A LYS 188.A NZ PRO 249.A O no hydrogen 3.073 N/A LYS 188.A NZ ARG 252.A O no hydrogen 2.777 N/A SER 189.A N THR 186.A O no hydrogen 2.871 N/A SER 189.A OG GLU 178.A OE1 no hydrogen 3.176 N/A SER 189.A OG SER 179.A OG no hydrogen 3.382 N/A ASP 190.A N THR 186.A O no hydrogen 3.227 N/A VAL 191.A N SER 187.A O no hydrogen 2.820 N/A TRP 192.A N LYS 188.A O no hydrogen 3.111 N/A ALA 193.A N SER 189.A O no hydrogen 3.050 N/A PHE 194.A N ASP 190.A O no hydrogen 2.864 N/A GLY 195.A N VAL 191.A O no hydrogen 2.987 N/A VAL 196.A N TRP 192.A O no hydrogen 3.103 N/A THR 197.A N ALA 193.A O no hydrogen 2.843 N/A THR 197.A OG1 ALA 193.A O no hydrogen 2.816 N/A MET 198.A N PHE 194.A O no hydrogen 2.718 N/A TRP 199.A N GLY 195.A O no hydrogen 3.031 N/A TRP 199.A NE1 LYS 228.A O no hydrogen 2.750 N/A GLU 200.A N VAL 196.A O no hydrogen 2.834 N/A ILE 201.A N THR 197.A O no hydrogen 2.972 N/A ALA 202.A N MET 198.A O no hydrogen 2.896 N/A THR 203.A N TRP 199.A O no hydrogen 2.916 N/A THR 203.A OG1 TRP 199.A O no hydrogen 2.981 N/A THR 203.A OG1 GLU 200.A O no hydrogen 3.061 N/A ARG 204.A N ILE 201.A O no hydrogen 3.058 N/A ARG 204.A NH2 ILE 121.A O no hydrogen 2.207 N/A GLY 205.A N GLU 200.A O no hydrogen 2.821 N/A MET 206.A N THR 203.A OG1 no hydrogen 3.094 N/A VAL 212.A N TYR 209.A O no hydrogen 3.192 N/A GLN 213.A N GLU 216.A OE1 no hydrogen 3.196 N/A HIS 215.A NE2 GLN 213.A OE1 no hydrogen 2.219 N/A GLU 216.A N GLN 213.A O no hydrogen 3.084 N/A MET 217.A N ASN 214.A O no hydrogen 3.086 N/A TYR 220.A N GLU 216.A O no hydrogen 2.937 N/A LEU 221.A N MET 217.A O no hydrogen 3.186 N/A LEU 222.A N TYR 218.A O no hydrogen 2.783 N/A HIS 223.A N ASP 219.A O no hydrogen 3.287 N/A HIS 223.A ND1 ASP 219.A O no hydrogen 2.533 N/A GLY 224.A N LEU 221.A O no hydrogen 2.944 N/A ARG 226.A NE TRP 245.A O no hydrogen 3.020 N/A ARG 226.A NH1 LEU 221.A O no hydrogen 3.221 N/A ARG 226.A NH1 HIS 225.A O no hydrogen 2.676 N/A ARG 226.A NH2 TRP 245.A O no hydrogen 3.253 N/A GLN 229.A NE2 CYS 233.A O no hydrogen 2.901 N/A GLN 229.A NE2 ASP 235.A OD1 no hydrogen 3.191 N/A GLU 231.A N GLU 231.A OE1 no hydrogen 2.557 N/A CYS 233.A N PRO 230.A O no hydrogen 3.226 N/A CYS 233.A SG LEU 234.A O no hydrogen 3.521 N/A TYR 238.A N LEU 234.A O no hydrogen 2.996 N/A TYR 238.A OH LEU 227.A O no hydrogen 2.626 N/A GLU 239.A N ASP 235.A O no hydrogen 2.814 N/A ILE 240.A N GLU 236.A O no hydrogen 3.145 N/A MET 241.A N LEU 237.A O no hydrogen 3.041 N/A TYR 242.A N TYR 238.A O no hydrogen 2.756 N/A SER 243.A N GLU 239.A O no hydrogen 2.854 N/A SER 243.A OG ILE 240.A O no hydrogen 2.625 N/A CYS 244.A N MET 241.A O no hydrogen 2.972 N/A CYS 244.A SG ILE 240.A O no hydrogen 3.726 N/A TRP 245.A N TYR 242.A O no hydrogen 2.934 N/A ARG 246.A NH1 ASP 251.A O no hydrogen 3.171 N/A LEU 250.A N ASP 248.A OD1 no hydrogen 3.107 N/A ASP 251.A N ASP 248.A O no hydrogen 2.804 N/A ARG 252.A N PRO 249.A O no hydrogen 3.123 N/A ARG 252.A NE ARG 246.A O no hydrogen 2.750 N/A ARG 252.A NH1 GLU 178.A OE1 no hydrogen 2.866 N/A ARG 252.A NH1 LYS 188.A O no hydrogen 2.839 N/A ARG 252.A NH2 GLU 178.A OE1 no hydrogen 3.528 N/A ARG 252.A NH2 GLU 178.A OE2 no hydrogen 2.524 N/A ARG 252.A NH2 ARG 246.A O no hydrogen 3.147 N/A SER 256.A OG GLU 138.A OE2 no hydrogen 2.562 N/A VAL 257.A N THR 254.A OG1 no hydrogen 3.097 N/A LEU 258.A N THR 254.A O no hydrogen 2.848 N/A ARG 259.A N PHE 255.A O no hydrogen 2.718 N/A ARG 259.A NE GLU 138.A OE1 no hydrogen 2.866 N/A ARG 259.A NH1 GLU 263.A OE1 no hydrogen 3.200 N/A ARG 259.A NH2 GLU 138.A OE1 no hydrogen 3.423 N/A ARG 259.A NH2 GLU 138.A OE2 no hydrogen 2.881 N/A LEU 260.A N SER 256.A O no hydrogen 3.261 N/A GLN 261.A N VAL 257.A O no hydrogen 2.953 N/A LEU 262.A N LEU 258.A O no hydrogen 2.866 N/A GLU 263.A N ARG 259.A O no hydrogen 2.794 N/A ARG 264.A N LEU 260.A O no hydrogen 2.865 N/A LEU 265.A N GLN 261.A O no hydrogen 2.910 N/A LEU 266.A N LEU 262.A O no hydrogen 2.932 N/A GLU 267.A N GLU 263.A O no hydrogen 3.158 N/A SER 268.A N ARG 264.A O no hydrogen 3.212 N/A SER 268.A OG LEU 265.A O no hydrogen 2.713 N/A LEU 269.A N LEU 266.A O no hydrogen 3.133 N/A