Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7xm2_X.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N THR 280.A O no hydrogen 2.881 N/A ILE 4.A N TYR 21.A O no hydrogen 2.907 N/A TYR 5.A N ALA 278.A O no hydrogen 2.859 N/A THR 6.A N GLU 19.A O no hydrogen 2.778 N/A ALA 7.A N GLY 276.A O no hydrogen 2.753 N/A GLY 8.A N TYR 17.A O no hydrogen 2.780 N/A GLY 9.A N ARG 38.A O no hydrogen 2.675 N/A PHE 11.A N GLN 13.A O no hydrogen 3.193 N/A LEU 15.A N GLY 9.A O no hydrogen 2.884 N/A GLU 19.A N THR 6.A O no hydrogen 3.058 N/A ALA 20.A N LEU 29.A O no hydrogen 3.088 N/A TYR 21.A N ILE 4.A O no hydrogen 2.703 N/A ASN 22.A N THR 27.A O no hydrogen 3.053 N/A SER 24.A N ASN 22.A OD1 no hydrogen 3.032 N/A ASP 25.A N ASN 22.A O no hydrogen 3.211 N/A GLY 26.A N ASN 22.A O no hydrogen 2.748 N/A THR 27.A N ASP 25.A OD1 no hydrogen 2.991 N/A THR 27.A OG1 ASP 25.A OD1 no hydrogen 2.319 N/A TRP 28.A NE1 THR 266.A OG1 no hydrogen 3.193 N/A LEU 29.A N ALA 20.A O no hydrogen 2.884 N/A ARG 30.A NH2 ASP 33.A OD1 no hydrogen 2.960 N/A LEU 31.A N LEU 18.A O no hydrogen 2.919 N/A ALA 32.A N ASN 72.A OD1 no hydrogen 3.083 N/A LEU 34.A N SER 16.A O no hydrogen 2.853 N/A ARG 38.A N LEU 15.A O no hydrogen 2.836 N/A ARG 38.A NE GLY 54.A O no hydrogen 3.098 N/A ARG 38.A NH2 GLY 54.A O no hydrogen 3.037 N/A SER 39.A N ARG 56.A O no hydrogen 3.059 N/A GLY 40.A N GLY 274.A O no hydrogen 2.742 N/A ALA 42.A N VAL 53.A O no hydrogen 3.003 N/A CYS 44.A N TYR 51.A O no hydrogen 3.082 N/A VAL 46.A N LEU 49.A O no hydrogen 3.057 N/A LEU 49.A N VAL 46.A O no hydrogen 3.011 N/A LEU 50.A N TYR 67.A O no hydrogen 2.950 N/A TYR 51.A N CYS 44.A O no hydrogen 2.736 N/A ALA 52.A N ASP 65.A O no hydrogen 2.828 N/A VAL 53.A N ALA 42.A O no hydrogen 2.889 N/A GLY 54.A N ALA 63.A O no hydrogen 2.910 N/A GLY 55.A N ARG 84.A O no hydrogen 2.691 N/A ARG 56.A N SER 39.A O no hydrogen 2.921 N/A ARG 56.A NE ASP 60.A OD1 no hydrogen 2.916 N/A ARG 56.A NH1 ASP 60.A OD1 no hydrogen 3.160 N/A ASN 57.A N THR 59.A O no hydrogen 2.888 N/A ASN 57.A ND2 PRO 37.A O no hydrogen 3.200 N/A SER 61.A N GLY 55.A O no hydrogen 2.818 N/A ALA 63.A N SER 61.A OG no hydrogen 3.035 N/A ASP 65.A N ALA 52.A O no hydrogen 3.036 N/A CYS 66.A N SER 75.A O no hydrogen 2.880 N/A TYR 67.A N LEU 50.A O no hydrogen 2.632 N/A TYR 67.A OH ASN 72.A OD1 no hydrogen 2.607 N/A ASN 68.A N GLN 73.A O no hydrogen 3.093 N/A MET 70.A N ASN 68.A OD1 no hydrogen 2.967 N/A THR 71.A N ASN 68.A O no hydrogen 3.028 N/A THR 71.A OG1 ASN 68.A O no hydrogen 3.369 N/A ASN 72.A N ASN 68.A O no hydrogen 2.728 N/A TRP 74.A NE1 ALA 32.A O no hydrogen 2.793 N/A SER 75.A N CYS 66.A O no hydrogen 2.690 N/A CYS 77.A N LEU 64.A O no hydrogen 2.859 N/A CYS 77.A SG SER 75.A O no hydrogen 3.844 N/A CYS 77.A SG TYR 114.A OH no hydrogen 3.751 N/A ALA 78.A N ASP 119.A OD1 no hydrogen 2.901 N/A MET 80.A N SER 62.A O no hydrogen 2.749 N/A SER 81.A N GLU 112.A OE1 no hydrogen 2.730 N/A SER 81.A OG GLU 112.A OE1 no hydrogen 3.304 N/A SER 81.A OG GLU 112.A OE2 no hydrogen 2.751 N/A ARG 84.A N SER 61.A O no hydrogen 2.930 N/A ARG 84.A NE GLU 112.A OE2 no hydrogen 2.996 N/A ARG 84.A NH1 GLY 100.A O no hydrogen 2.982 N/A ARG 84.A NH1 SER 110.A O no hydrogen 2.920 N/A ARG 84.A NH1 SER 110.A OG no hydrogen 3.309 N/A ARG 84.A NH2 SER 110.A OG no hydrogen 2.977 N/A ARG 84.A NH2 GLU 112.A OE2 no hydrogen 2.771 N/A ASN 85.A N SER 102.A O no hydrogen 2.907 N/A ARG 86.A N GLY 40.A O no hydrogen 2.905 N/A GLY 88.A N VAL 99.A O no hydrogen 3.158 N/A GLY 90.A N TYR 97.A O no hydrogen 3.144 N/A ILE 92.A N HIS 95.A O no hydrogen 2.966 N/A HIS 95.A N ILE 92.A O no hydrogen 2.865 N/A HIS 95.A ND1 ASP 93.A O no hydrogen 2.751 N/A ILE 96.A N TYR 114.A O no hydrogen 3.019 N/A TYR 97.A N GLY 90.A O no hydrogen 2.727 N/A ALA 98.A N GLU 112.A O no hydrogen 2.746 N/A VAL 99.A N GLY 88.A O no hydrogen 2.708 N/A GLY 100.A N SER 110.A O no hydrogen 3.227 N/A GLY 101.A N ARG 131.A O no hydrogen 2.848 N/A SER 102.A N ASN 85.A O no hydrogen 2.900 N/A SER 102.A OG ASN 85.A O no hydrogen 3.478 N/A HIS 103.A N ILE 106.A O no hydrogen 2.937 N/A GLY 104.A N ASP 60.A OD2 no hydrogen 2.733 N/A ILE 106.A N HIS 103.A O no hydrogen 2.779 N/A HIS 107.A ND1 CYS 105.A O no hydrogen 2.698 N/A HIS 108.A N GLY 101.A O no hydrogen 2.788 N/A HIS 108.A NE2 PRO 83.A O no hydrogen 2.744 N/A ASN 109.A ND2 MET 127.A O no hydrogen 3.481 N/A GLU 112.A N ALA 98.A O no hydrogen 3.091 N/A ARG 113.A N HIS 122.A O no hydrogen 2.774 N/A TYR 114.A N ILE 96.A O no hydrogen 2.695 N/A TYR 114.A OH ASP 119.A OD1 no hydrogen 2.522 N/A GLU 115.A N GLU 120.A O no hydrogen 2.903 N/A GLU 117.A N GLU 117.A OE2 no hydrogen 2.950 N/A ARG 118.A N GLU 115.A O no hydrogen 3.153 N/A ARG 118.A NH1 GLU 115.A OE2 no hydrogen 2.578 N/A ASP 119.A N PRO 116.A O no hydrogen 3.219 N/A TRP 121.A NE1 ALA 78.A O no hydrogen 2.880 N/A HIS 122.A N ARG 113.A O no hydrogen 2.873 N/A HIS 122.A NE2 GLU 120.A OE2 no hydrogen 2.963 N/A VAL 124.A N VAL 111.A O no hydrogen 2.984 N/A ALA 125.A N ASN 166.A OD1 no hydrogen 2.895 N/A MET 127.A N ASN 109.A O no hydrogen 2.805 N/A LEU 128.A N GLU 159.A OE1 no hydrogen 2.753 N/A THR 129.A OG1 GLU 159.A OE2 no hydrogen 3.262 N/A ARG 130.A NH1 HIS 107.A O no hydrogen 2.913 N/A ARG 131.A N HIS 108.A O no hydrogen 3.183 N/A ARG 131.A NE GLU 159.A OE2 no hydrogen 2.869 N/A ARG 131.A NH1 GLY 147.A O no hydrogen 3.123 N/A ARG 131.A NH1 SER 157.A O no hydrogen 2.845 N/A ARG 131.A NH1 SER 157.A OG no hydrogen 3.354 N/A ARG 131.A NH2 SER 157.A OG no hydrogen 3.220 N/A ARG 131.A NH2 GLU 159.A OE2 no hydrogen 2.860 N/A ILE 132.A N PHE 149.A O no hydrogen 3.004 N/A GLY 133.A N ARG 86.A O no hydrogen 2.965 N/A GLY 135.A N VAL 146.A O no hydrogen 2.974 N/A ALA 137.A N TYR 144.A O no hydrogen 2.993 N/A LEU 139.A N LEU 142.A O no hydrogen 2.872 N/A LEU 142.A N LEU 139.A O no hydrogen 2.816 N/A LEU 143.A N TYR 161.A O no hydrogen 3.200 N/A TYR 144.A N ALA 137.A O no hydrogen 2.738 N/A ALA 145.A N GLU 159.A O no hydrogen 2.858 N/A VAL 146.A N GLY 135.A O no hydrogen 2.729 N/A GLY 147.A N SER 157.A O no hydrogen 3.028 N/A GLY 148.A N ARG 178.A O no hydrogen 2.881 N/A PHE 149.A N ILE 132.A O no hydrogen 2.833 N/A ASP 150.A N ASN 153.A O no hydrogen 3.040 N/A THR 152.A N ASP 150.A OD1 no hydrogen 2.725 N/A THR 152.A OG1 ASP 150.A OD1 no hydrogen 3.197 N/A THR 152.A OG1 ASN 153.A OD1 no hydrogen 2.923 N/A ASN 153.A N ASP 150.A OD1 no hydrogen 2.720 N/A ARG 154.A NH1 SER 179.A OG no hydrogen 2.807 N/A LEU 155.A N GLY 148.A O no hydrogen 2.946 N/A ASN 156.A ND2 MET 174.A O no hydrogen 3.215 N/A GLU 159.A N ALA 145.A O no hydrogen 3.004 N/A CYS 160.A N ARG 169.A O no hydrogen 2.718 N/A TYR 161.A N LEU 143.A O no hydrogen 2.633 N/A TYR 161.A OH ASN 166.A OD1 no hydrogen 2.619 N/A TYR 162.A N GLU 167.A O no hydrogen 2.790 N/A ASN 166.A N TYR 162.A O no hydrogen 2.605 N/A ASN 166.A N PRO 163.A O no hydrogen 3.163 N/A TRP 168.A NE1 ALA 125.A O no hydrogen 2.900 N/A ARG 169.A N CYS 160.A O no hydrogen 2.871 N/A ILE 171.A N ALA 158.A O no hydrogen 2.922 N/A THR 172.A OG1 GLU 213.A O no hydrogen 2.721 N/A MET 174.A N ASN 156.A O no hydrogen 2.788 N/A ASN 175.A N GLU 206.A OE1 no hydrogen 2.797 N/A ASN 175.A ND2 GLU 206.A OE1 no hydrogen 2.774 N/A ASN 175.A ND2 TRP 215.A O no hydrogen 2.968 N/A THR 176.A N GLU 206.A OE2 no hydrogen 3.024 N/A ARG 178.A N LEU 155.A O no hydrogen 3.023 N/A ARG 178.A NE GLU 206.A OE2 no hydrogen 3.055 N/A ARG 178.A NH1 GLY 194.A O no hydrogen 2.838 N/A ARG 178.A NH1 SER 204.A O no hydrogen 3.040 N/A ARG 178.A NH1 SER 204.A OG no hydrogen 3.406 N/A ARG 178.A NH2 SER 204.A OG no hydrogen 2.796 N/A ARG 178.A NH2 GLU 206.A OE2 no hydrogen 3.051 N/A SER 179.A N TYR 196.A O no hydrogen 2.877 N/A SER 179.A OG TYR 196.A O no hydrogen 3.392 N/A GLY 180.A N GLY 133.A O no hydrogen 2.952 N/A GLY 182.A N ALA 193.A O no hydrogen 2.909 N/A CYS 184.A N TYR 191.A O no hydrogen 3.135 N/A LEU 186.A N CYS 189.A O no hydrogen 3.054 N/A CYS 189.A N LEU 186.A O no hydrogen 3.092 N/A CYS 189.A SG HIS 187.A O no hydrogen 4.029 N/A ILE 190.A N TYR 208.A O no hydrogen 3.122 N/A TYR 191.A N CYS 184.A O no hydrogen 2.850 N/A ALA 192.A N GLU 206.A O no hydrogen 2.861 N/A ALA 193.A N GLY 182.A O no hydrogen 2.810 N/A GLY 194.A N SER 204.A O no hydrogen 3.004 N/A GLY 195.A N ARG 225.A O no hydrogen 2.732 N/A TYR 196.A N SER 179.A O no hydrogen 2.695 N/A ASP 197.A N ASP 200.A O no hydrogen 3.231 N/A GLN 199.A N ASP 197.A OD1 no hydrogen 2.681 N/A ASP 200.A N ASP 197.A OD1 no hydrogen 2.960 N/A LEU 202.A N GLY 195.A O no hydrogen 2.794 N/A GLU 206.A N ALA 192.A O no hydrogen 3.092 N/A ARG 207.A N THR 216.A O no hydrogen 2.781 N/A ARG 207.A NH1 TYR 191.A OH no hydrogen 2.675 N/A TYR 208.A N ILE 190.A O no hydrogen 2.631 N/A ASP 209.A N THR 214.A O no hydrogen 3.047 N/A THR 212.A N ASP 209.A OD1 no hydrogen 2.689 N/A GLU 213.A N ASP 209.A O no hydrogen 2.749 N/A THR 214.A OG1 THR 212.A O no hydrogen 3.137 N/A TRP 215.A NE1 THR 172.A O no hydrogen 2.857 N/A THR 216.A N ARG 207.A O no hydrogen 2.905 N/A VAL 218.A N VAL 205.A O no hydrogen 2.735 N/A ALA 219.A N ASP 260.A OD1 no hydrogen 2.907 N/A MET 221.A N ASN 203.A O no hydrogen 2.826 N/A LYS 222.A N GLU 253.A OE1 no hydrogen 2.718 N/A HIS 223.A N GLU 253.A OE2 no hydrogen 3.096 N/A ARG 224.A NH1 GLN 201.A O no hydrogen 2.786 N/A ARG 225.A N LEU 202.A O no hydrogen 2.874 N/A ARG 225.A NH1 GLY 241.A O no hydrogen 2.743 N/A ARG 225.A NH1 SER 251.A O no hydrogen 3.168 N/A ARG 225.A NH2 SER 251.A OG.A no hydrogen 3.202 N/A ARG 225.A NH2 SER 251.A OG.B no hydrogen 3.130 N/A ARG 225.A NH2 GLU 253.A OE2 no hydrogen 2.714 N/A SER 226.A N TYR 243.A O no hydrogen 2.913 N/A ALA 227.A N GLY 180.A O no hydrogen 2.640 N/A GLY 229.A N LEU 240.A O no hydrogen 2.875 N/A THR 231.A N TYR 238.A O no hydrogen 2.923 N/A HIS 233.A N ARG 236.A O no hydrogen 2.883 N/A ARG 236.A N HIS 233.A O no hydrogen 2.962 N/A ILE 237.A N TYR 255.A O no hydrogen 3.105 N/A TYR 238.A N THR 231.A O no hydrogen 2.883 N/A VAL 239.A N GLU 253.A O no hydrogen 3.027 N/A LEU 240.A N GLY 229.A O no hydrogen 2.766 N/A GLY 241.A N SER 251.A O no hydrogen 3.085 N/A GLY 242.A N ARG 272.A O no hydrogen 2.858 N/A TYR 243.A N SER 226.A O no hydrogen 2.901 N/A ASP 244.A N THR 247.A O no hydrogen 3.210 N/A HIS 246.A N ASP 244.A OD1 no hydrogen 2.803 N/A THR 247.A N ASP 244.A OD1 no hydrogen 2.778 N/A THR 247.A OG1 ASP 244.A OD2 no hydrogen 3.365 N/A LEU 249.A N GLY 242.A O no hydrogen 2.892 N/A SER 251.A OG.A GLU 264.A OE2 no hydrogen 3.115 N/A SER 251.A OG.B GLU 264.A OE2 no hydrogen 3.188 N/A VAL 252.A N THR 266.A O no hydrogen 3.085 N/A GLU 253.A N VAL 239.A O no hydrogen 3.168 N/A CYS 254.A N SER 263.A O no hydrogen 2.694 N/A CYS 254.A SG ILE 237.A O no hydrogen 3.901 N/A TYR 255.A N ILE 237.A O no hydrogen 2.724 N/A TYR 255.A OH ASP 260.A OD1 no hydrogen 2.748 N/A ASP 256.A N THR 261.A O no hydrogen 2.843 N/A THR 259.A N ASP 256.A OD2 no hydrogen 3.025 N/A THR 259.A OG1 ASP 256.A O no hydrogen 3.345 N/A THR 259.A OG1 ASP 256.A OD2 no hydrogen 2.468 N/A THR 259.A OG1 THR 261.A OG1 no hydrogen 3.268 N/A ASP 260.A N PRO 257.A O no hydrogen 3.399 N/A THR 261.A N ASP 256.A O no hydrogen 3.301 N/A THR 261.A OG1 THR 259.A O no hydrogen 3.082 N/A THR 261.A OG1 THR 259.A OG1 no hydrogen 3.268 N/A TRP 262.A NE1 ALA 219.A O no hydrogen 2.784 N/A SER 263.A N CYS 254.A O no hydrogen 2.950 N/A SER 263.A OG CYS 254.A O no hydrogen 3.502 N/A VAL 265.A N VAL 252.A O no hydrogen 3.035 N/A ARG 267.A NH1 GLU 264.A OE1 no hydrogen 3.134 N/A MET 268.A N ASP 250.A O no hydrogen 2.803 N/A THR 269.A OG1 GLU 19.A OE1 no hydrogen 3.120 N/A THR 269.A OG1 GLU 19.A OE2 no hydrogen 2.577 N/A ARG 272.A N LEU 249.A O no hydrogen 2.926 N/A ARG 272.A NE SER 270.A O no hydrogen 3.032 N/A ARG 272.A NH1 GLU 19.A OE1 no hydrogen 2.734 N/A ARG 272.A NH2 GLU 19.A OE1 no hydrogen 2.757 N/A ARG 272.A NH2 THR 269.A OG1 no hydrogen 3.268 N/A ARG 272.A NH2 SER 270.A O no hydrogen 3.228 N/A SER 273.A N TYR 10.A O no hydrogen 3.067 N/A GLY 274.A N ALA 227.A O no hydrogen 2.882 N/A GLY 276.A N ALA 7.A O no hydrogen 2.946 N/A ALA 278.A N TYR 5.A O no hydrogen 3.217 N/A THR 280.A N LEU 3.A O no hydrogen 3.121 N/A