Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7xm5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N THR 281.A O no hydrogen 2.920 N/A ILE 5.A N TYR 22.A O no hydrogen 2.925 N/A TYR 6.A N ALA 279.A O no hydrogen 2.694 N/A THR 7.A N GLU 20.A O no hydrogen 2.933 N/A ALA 8.A N GLY 277.A O no hydrogen 2.728 N/A GLY 9.A N TYR 18.A O no hydrogen 2.788 N/A GLY 10.A N ARG 39.A O no hydrogen 2.832 N/A TYR 11.A N SER 274.A O no hydrogen 2.858 N/A PHE 12.A N GLN 14.A O no hydrogen 2.971 N/A SER 15.A OG SER 40.A OG no hydrogen 3.365 N/A SER 15.A OG ARG 57.A O no hydrogen 3.404 N/A LEU 16.A N GLY 10.A O no hydrogen 2.602 N/A GLU 20.A N THR 7.A O no hydrogen 3.043 N/A ALA 21.A N LEU 30.A O no hydrogen 3.020 N/A TYR 22.A N ILE 5.A O no hydrogen 2.818 N/A ASN 23.A N THR 28.A O no hydrogen 2.818 N/A SER 25.A N ASN 23.A OD1 no hydrogen 2.896 N/A GLY 27.A N ASN 23.A O no hydrogen 2.865 N/A THR 28.A N ASP 26.A OD1 no hydrogen 3.019 N/A THR 28.A OG1 ASP 26.A OD1 no hydrogen 2.506 N/A THR 28.A OG1 ASP 26.A OD2 no hydrogen 3.274 N/A TRP 29.A NE1 THR 267.A OG1 no hydrogen 3.226 N/A LEU 30.A N ALA 21.A O no hydrogen 2.702 N/A ARG 31.A NH2 ASP 34.A OD1 no hydrogen 2.802 N/A LEU 32.A N LEU 19.A O no hydrogen 2.951 N/A ALA 33.A N ASN 73.A OD1 no hydrogen 3.020 N/A LEU 35.A N SER 17.A O no hydrogen 2.910 N/A ARG 39.A N LEU 16.A O no hydrogen 2.964 N/A ARG 39.A NH1 GLY 55.A O no hydrogen 2.743 N/A SER 40.A N ARG 57.A O no hydrogen 3.193 N/A SER 40.A OG SER 15.A OG no hydrogen 3.365 N/A GLY 41.A N GLY 275.A O no hydrogen 2.962 N/A ALA 43.A N VAL 54.A O no hydrogen 3.039 N/A CYS 45.A N TYR 52.A O no hydrogen 3.151 N/A VAL 47.A N LEU 50.A O no hydrogen 2.933 N/A LEU 50.A N VAL 47.A O no hydrogen 2.942 N/A LEU 51.A N TYR 68.A O no hydrogen 3.013 N/A TYR 52.A N CYS 45.A O no hydrogen 2.795 N/A ALA 53.A N ASP 66.A O no hydrogen 2.851 N/A VAL 54.A N ALA 43.A O no hydrogen 3.002 N/A GLY 55.A N ALA 64.A O no hydrogen 2.982 N/A GLY 56.A N ARG 85.A O no hydrogen 2.943 N/A ARG 57.A N SER 40.A O no hydrogen 2.762 N/A ASN 58.A N THR 60.A O no hydrogen 2.399 N/A SER 62.A N GLY 56.A O no hydrogen 2.758 N/A ALA 64.A N SER 62.A OG no hydrogen 3.007 N/A ASP 66.A N ALA 53.A O no hydrogen 2.966 N/A CYS 67.A N SER 76.A O no hydrogen 2.840 N/A CYS 67.A SG LEU 51.A O no hydrogen 3.823 N/A TYR 68.A N LEU 51.A O no hydrogen 2.746 N/A TYR 68.A OH ASN 73.A OD1 no hydrogen 2.632 N/A ASN 69.A N GLN 74.A O no hydrogen 2.917 N/A MET 71.A N ASN 69.A OD1 no hydrogen 2.923 N/A THR 72.A N ASN 69.A O no hydrogen 3.270 N/A TRP 75.A NE1 ALA 33.A O no hydrogen 2.876 N/A SER 76.A N CYS 67.A O no hydrogen 2.614 N/A CYS 78.A N LEU 65.A O no hydrogen 2.840 N/A CYS 78.A SG TYR 115.A OH no hydrogen 3.772 N/A ALA 79.A N ASP 120.A OD1 no hydrogen 2.817 N/A MET 81.A N SER 63.A O no hydrogen 2.811 N/A SER 82.A N GLU 113.A OE1 no hydrogen 2.910 N/A SER 82.A OG GLU 113.A OE1 no hydrogen 3.002 N/A SER 82.A OG GLU 113.A OE2 no hydrogen 2.881 N/A ARG 85.A N SER 62.A O no hydrogen 3.034 N/A ARG 85.A NE GLU 113.A OE2 no hydrogen 3.017 N/A ARG 85.A NH1 GLY 101.A O no hydrogen 2.722 N/A ARG 85.A NH1 SER 111.A O no hydrogen 2.986 N/A ARG 85.A NH2 SER 111.A OG no hydrogen 3.082 N/A ARG 85.A NH2 GLU 113.A OE2 no hydrogen 2.597 N/A ASN 86.A N SER 103.A O no hydrogen 2.780 N/A ARG 87.A N GLY 41.A O no hydrogen 2.886 N/A ILE 88.A N GLY 41.A O no hydrogen 3.455 N/A GLY 89.A N VAL 100.A O no hydrogen 3.209 N/A GLY 91.A N TYR 98.A O no hydrogen 3.022 N/A ILE 93.A N HIS 96.A O no hydrogen 2.867 N/A HIS 96.A N ILE 93.A O no hydrogen 2.968 N/A HIS 96.A NE2 GLU 118.A OE2 no hydrogen 2.801 N/A ILE 97.A N TYR 115.A O no hydrogen 3.203 N/A TYR 98.A N GLY 91.A O no hydrogen 2.615 N/A ALA 99.A N GLU 113.A O no hydrogen 2.768 N/A VAL 100.A N GLY 89.A O no hydrogen 2.788 N/A GLY 101.A N SER 111.A O no hydrogen 3.119 N/A GLY 102.A N ARG 132.A O no hydrogen 2.832 N/A SER 103.A N ASN 86.A O no hydrogen 2.824 N/A SER 103.A OG ASN 86.A O no hydrogen 3.555 N/A HIS 104.A N ILE 107.A O no hydrogen 2.967 N/A GLY 105.A N ASP 61.A OD2 no hydrogen 2.663 N/A ILE 107.A N HIS 104.A O no hydrogen 2.901 N/A HIS 109.A N GLY 102.A O no hydrogen 2.836 N/A HIS 109.A NE2 PRO 84.A O no hydrogen 2.927 N/A ASN 110.A ND2 MET 128.A O no hydrogen 3.045 N/A GLU 113.A N ALA 99.A O no hydrogen 3.051 N/A ARG 114.A N HIS 123.A O no hydrogen 2.810 N/A ARG 114.A NH2 GLU 116.A OE2 no hydrogen 2.849 N/A TYR 115.A N ILE 97.A O no hydrogen 2.751 N/A TYR 115.A OH ASP 120.A OD1 no hydrogen 2.513 N/A GLU 116.A N GLU 121.A O no hydrogen 2.771 N/A GLU 118.A N GLU 118.A OE1 no hydrogen 2.627 N/A ARG 119.A N GLU 116.A O no hydrogen 3.019 N/A ARG 119.A NH2 GLU 116.A OE1 no hydrogen 2.814 N/A GLU 121.A N GLU 116.A O no hydrogen 3.496 N/A TRP 122.A NE1 ALA 79.A O no hydrogen 2.853 N/A HIS 123.A N ARG 114.A O no hydrogen 2.899 N/A HIS 123.A NE2 GLU 121.A OE1 no hydrogen 3.022 N/A VAL 125.A N VAL 112.A O no hydrogen 2.892 N/A ALA 126.A N ASN 167.A OD1 no hydrogen 2.957 N/A MET 128.A N ASN 110.A O no hydrogen 2.753 N/A LEU 129.A N GLU 160.A OE1 no hydrogen 2.808 N/A THR 130.A N GLU 160.A OE2 no hydrogen 3.157 N/A THR 130.A OG1 GLU 160.A OE2 no hydrogen 3.219 N/A ARG 131.A NH1 HIS 108.A O no hydrogen 2.867 N/A ARG 132.A N HIS 109.A O no hydrogen 3.038 N/A ARG 132.A NE GLU 160.A OE2 no hydrogen 2.914 N/A ARG 132.A NH1 GLY 148.A O no hydrogen 2.902 N/A ARG 132.A NH1 SER 158.A O no hydrogen 3.197 N/A ARG 132.A NH2 SER 158.A OG no hydrogen 2.849 N/A ARG 132.A NH2 GLU 160.A OE2 no hydrogen 2.965 N/A ILE 133.A N PHE 150.A O no hydrogen 2.971 N/A GLY 134.A N ARG 87.A O no hydrogen 2.936 N/A GLY 136.A N VAL 147.A O no hydrogen 2.832 N/A ALA 138.A N TYR 145.A O no hydrogen 3.012 N/A LEU 140.A N LEU 143.A O no hydrogen 2.922 N/A ARG 142.A NE ASP 94.A OD2 no hydrogen 2.711 N/A ARG 142.A NH1 GLU 165.A OE2 no hydrogen 3.032 N/A ARG 142.A NH2 ASP 94.A OD2 no hydrogen 2.667 N/A LEU 143.A N LEU 140.A O no hydrogen 3.100 N/A LEU 144.A N TYR 162.A O no hydrogen 3.260 N/A TYR 145.A N ALA 138.A O no hydrogen 2.657 N/A ALA 146.A N GLU 160.A O no hydrogen 2.765 N/A VAL 147.A N GLY 136.A O no hydrogen 2.696 N/A GLY 148.A N SER 158.A O no hydrogen 3.019 N/A GLY 149.A N ARG 179.A O no hydrogen 2.707 N/A PHE 150.A N ILE 133.A O no hydrogen 2.801 N/A ASP 151.A N ASN 154.A O no hydrogen 3.091 N/A THR 153.A N ASP 151.A OD1 no hydrogen 2.692 N/A ASN 154.A N ASP 151.A OD1 no hydrogen 2.878 N/A ARG 155.A NH1 SER 180.A OG no hydrogen 2.967 N/A LEU 156.A N GLY 149.A O no hydrogen 2.834 N/A ASN 157.A ND2 MET 175.A O no hydrogen 3.024 N/A GLU 160.A N ALA 146.A O no hydrogen 2.902 N/A CYS 161.A N ARG 170.A O no hydrogen 2.878 N/A TYR 162.A N LEU 144.A O no hydrogen 2.651 N/A TYR 162.A OH ASN 167.A OD1 no hydrogen 2.627 N/A TYR 163.A N GLU 168.A O no hydrogen 2.733 N/A TRP 169.A NE1 ALA 126.A O no hydrogen 2.864 N/A ARG 170.A N CYS 161.A O no hydrogen 2.939 N/A ARG 170.A NE GLU 168.A OE2 no hydrogen 3.182 N/A ILE 172.A N ALA 159.A O no hydrogen 2.882 N/A THR 173.A OG1 GLU 214.A O no hydrogen 2.924 N/A MET 175.A N ASN 157.A O no hydrogen 2.809 N/A ASN 176.A N GLU 207.A OE1 no hydrogen 2.969 N/A ASN 176.A ND2 GLU 207.A OE1 no hydrogen 2.694 N/A ASN 176.A ND2 TRP 216.A O no hydrogen 2.988 N/A THR 177.A N GLU 207.A OE2 no hydrogen 3.098 N/A ARG 179.A N LEU 156.A O no hydrogen 2.960 N/A ARG 179.A NE GLU 207.A OE2 no hydrogen 3.005 N/A ARG 179.A NH1 GLY 195.A O no hydrogen 2.728 N/A ARG 179.A NH1 SER 205.A O no hydrogen 3.101 N/A ARG 179.A NH1 SER 205.A OG no hydrogen 3.189 N/A ARG 179.A NH2 SER 205.A OG no hydrogen 2.874 N/A ARG 179.A NH2 GLU 207.A OE2 no hydrogen 2.842 N/A SER 180.A N TYR 197.A O no hydrogen 3.028 N/A SER 180.A OG TYR 197.A O no hydrogen 3.364 N/A GLY 181.A N GLY 134.A O no hydrogen 2.860 N/A GLY 183.A N ALA 194.A O no hydrogen 2.901 N/A CYS 185.A N TYR 192.A O no hydrogen 3.060 N/A LEU 187.A N CYS 190.A O no hydrogen 2.984 N/A CYS 190.A N LEU 187.A O no hydrogen 3.108 N/A ILE 191.A N TYR 209.A O no hydrogen 3.241 N/A TYR 192.A N CYS 185.A O no hydrogen 2.793 N/A ALA 193.A N GLU 207.A O no hydrogen 2.823 N/A ALA 194.A N GLY 183.A O no hydrogen 2.710 N/A GLY 195.A N SER 205.A O no hydrogen 2.934 N/A GLY 196.A N ARG 226.A O no hydrogen 2.890 N/A TYR 197.A N SER 180.A O no hydrogen 2.771 N/A ASP 198.A N ASP 201.A O no hydrogen 3.131 N/A GLN 200.A N ASP 198.A OD1 no hydrogen 2.752 N/A ASP 201.A N ASP 198.A OD1 no hydrogen 2.863 N/A LEU 203.A N GLY 196.A O no hydrogen 2.709 N/A GLU 207.A N ALA 193.A O no hydrogen 3.029 N/A ARG 208.A N THR 217.A O no hydrogen 2.762 N/A TYR 209.A N ILE 191.A O no hydrogen 2.849 N/A ASP 210.A N THR 215.A O no hydrogen 3.024 N/A THR 213.A N ASP 210.A OD2 no hydrogen 3.103 N/A THR 213.A OG1 ASP 210.A OD2 no hydrogen 3.178 N/A GLU 214.A N VAL 211.A O no hydrogen 3.103 N/A THR 215.A N ASP 210.A O no hydrogen 3.373 N/A TRP 216.A NE1 THR 173.A O no hydrogen 3.058 N/A THR 217.A N ARG 208.A O no hydrogen 2.678 N/A VAL 219.A N VAL 206.A O no hydrogen 2.742 N/A ALA 220.A N ASP 261.A OD1 no hydrogen 2.884 N/A MET 222.A N ASN 204.A O no hydrogen 2.910 N/A LYS 223.A N GLU 254.A OE2 no hydrogen 2.551 N/A HIS 224.A N GLU 254.A OE1 no hydrogen 2.837 N/A HIS 224.A NE2 GLU 265.A OE2 no hydrogen 3.128 N/A ARG 225.A NH1 GLN 202.A O no hydrogen 2.653 N/A ARG 226.A N LEU 203.A O no hydrogen 3.001 N/A ARG 226.A NE HIS 224.A O no hydrogen 3.342 N/A ARG 226.A NH1 GLY 242.A O no hydrogen 2.661 N/A ARG 226.A NH1 SER 252.A O no hydrogen 3.150 N/A ARG 226.A NH2 SER 252.A OG no hydrogen 3.280 N/A ARG 226.A NH2 GLU 254.A OE1 no hydrogen 2.773 N/A SER 227.A N TYR 244.A O no hydrogen 2.866 N/A ALA 228.A N GLY 181.A O no hydrogen 2.809 N/A GLY 230.A N LEU 241.A O no hydrogen 2.978 N/A THR 232.A N TYR 239.A O no hydrogen 2.927 N/A HIS 234.A N ARG 237.A O no hydrogen 2.939 N/A ARG 237.A N HIS 234.A O no hydrogen 3.090 N/A ILE 238.A N TYR 256.A O no hydrogen 3.199 N/A TYR 239.A N THR 232.A O no hydrogen 2.869 N/A VAL 240.A N GLU 254.A O no hydrogen 3.078 N/A LEU 241.A N GLY 230.A O no hydrogen 2.843 N/A GLY 242.A N SER 252.A O no hydrogen 3.070 N/A GLY 243.A N ARG 273.A O no hydrogen 2.762 N/A TYR 244.A N SER 227.A O no hydrogen 2.863 N/A ASP 245.A N THR 248.A O no hydrogen 3.148 N/A HIS 247.A N ASP 245.A OD1 no hydrogen 2.749 N/A THR 248.A N ASP 245.A OD1 no hydrogen 2.748 N/A THR 248.A OG1 ASP 245.A OD2 no hydrogen 3.098 N/A LEU 250.A N GLY 243.A O no hydrogen 2.760 N/A SER 252.A OG GLU 265.A OE2 no hydrogen 3.077 N/A VAL 253.A N THR 267.A O no hydrogen 3.280 N/A GLU 254.A N VAL 240.A O no hydrogen 3.262 N/A CYS 255.A N SER 264.A O no hydrogen 2.653 N/A CYS 255.A SG ILE 238.A O no hydrogen 3.837 N/A TYR 256.A N ILE 238.A O no hydrogen 2.815 N/A TYR 256.A OH ASP 261.A OD1 no hydrogen 2.685 N/A ASP 257.A N THR 262.A O no hydrogen 2.839 N/A ASP 259.A N ASP 257.A OD1 no hydrogen 3.133 N/A THR 260.A N ASP 257.A O no hydrogen 3.222 N/A THR 262.A N ASP 257.A O no hydrogen 3.377 N/A THR 262.A OG1 THR 260.A O no hydrogen 3.301 N/A TRP 263.A NE1 ALA 220.A O no hydrogen 2.650 N/A SER 264.A N CYS 255.A O no hydrogen 2.934 N/A VAL 266.A N VAL 253.A O no hydrogen 2.932 N/A THR 267.A OG1 ARG 268.A O no hydrogen 3.466 N/A ARG 268.A N THR 267.A OG1 no hydrogen 2.601 N/A MET 269.A N ASP 251.A O no hydrogen 2.656 N/A THR 270.A OG1 GLU 20.A OE1 no hydrogen 3.462 N/A THR 270.A OG1 GLU 20.A OE2 no hydrogen 2.713 N/A ARG 273.A N LEU 250.A O no hydrogen 2.976 N/A ARG 273.A NH1 GLU 20.A OE1 no hydrogen 2.672 N/A ARG 273.A NH2 GLU 20.A OE1 no hydrogen 3.038 N/A ARG 273.A NH2 THR 270.A OG1 no hydrogen 3.314 N/A ARG 273.A NH2 SER 271.A OG no hydrogen 2.974 N/A SER 274.A N TYR 11.A O no hydrogen 3.200 N/A GLY 275.A N ALA 228.A O no hydrogen 2.835 N/A GLY 277.A N ALA 8.A O no hydrogen 2.894 N/A ALA 279.A N TYR 6.A O no hydrogen 2.946 N/A THR 281.A N LEU 4.A O no hydrogen 3.208 N/A