Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7xot_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N THR 282.A O no hydrogen 2.743 N/A ILE 4.A N TYR 21.A O no hydrogen 2.981 N/A TYR 5.A N ALA 280.A O no hydrogen 2.723 N/A THR 6.A N GLU 19.A O no hydrogen 2.694 N/A ALA 7.A N GLY 278.A O no hydrogen 2.723 N/A GLY 8.A N TYR 17.A O no hydrogen 2.671 N/A GLY 9.A N ARG 38.A O no hydrogen 2.892 N/A PHE 11.A N GLN 13.A O no hydrogen 3.098 N/A SER 14.A OG SER 39.A OG no hydrogen 3.359 N/A LEU 15.A N GLY 9.A O no hydrogen 2.862 N/A GLU 19.A N THR 6.A O no hydrogen 2.973 N/A ALA 20.A N LEU 29.A O no hydrogen 3.109 N/A TYR 21.A N ILE 4.A O no hydrogen 2.764 N/A ASN 22.A N THR 27.A O no hydrogen 2.955 N/A SER 24.A N ASN 22.A OD1 no hydrogen 2.791 N/A GLY 26.A N ASN 22.A O no hydrogen 2.721 N/A THR 27.A N ASP 25.A OD1 no hydrogen 2.870 N/A THR 27.A OG1 ASP 25.A OD1 no hydrogen 2.406 N/A THR 27.A OG1 ASP 25.A OD2 no hydrogen 3.422 N/A TRP 28.A NE1 THR 268.A OG1 no hydrogen 3.038 N/A LEU 29.A N ALA 20.A O no hydrogen 2.788 N/A ARG 30.A NH2 ASP 33.A OD1 no hydrogen 2.985 N/A LEU 31.A N LEU 18.A O no hydrogen 2.925 N/A ALA 32.A N ASN 74.A OD1 no hydrogen 3.092 N/A LEU 34.A N SER 16.A O no hydrogen 2.917 N/A ARG 38.A N LEU 15.A O no hydrogen 2.883 N/A ARG 38.A NH1 GLY 54.A O no hydrogen 2.700 N/A ARG 38.A NH2 ALA 52.A O no hydrogen 3.560 N/A SER 39.A N ARG 56.A O no hydrogen 2.940 N/A SER 39.A OG SER 14.A OG no hydrogen 3.359 N/A GLY 40.A N GLY 276.A O no hydrogen 3.113 N/A ALA 42.A N VAL 53.A O no hydrogen 3.011 N/A CYS 44.A N TYR 51.A O no hydrogen 3.105 N/A VAL 46.A N LEU 49.A O no hydrogen 3.086 N/A LEU 49.A N VAL 46.A O no hydrogen 2.874 N/A LEU 50.A N TYR 69.A O no hydrogen 2.825 N/A TYR 51.A N CYS 44.A O no hydrogen 2.820 N/A ALA 52.A N ASP 67.A O no hydrogen 2.883 N/A VAL 53.A N ALA 42.A O no hydrogen 2.915 N/A GLY 54.A N ALA 65.A O no hydrogen 2.988 N/A GLY 55.A N ARG 86.A O no hydrogen 2.896 N/A ARG 56.A N SER 39.A O no hydrogen 2.763 N/A ASN 57.A N THR 61.A O no hydrogen 2.870 N/A ASN 58.A N SER 14.A OG no hydrogen 2.603 N/A THR 61.A N ASN 57.A O no hydrogen 2.928 N/A SER 63.A N GLY 55.A O no hydrogen 2.668 N/A ALA 65.A N SER 63.A OG no hydrogen 2.919 N/A ASP 67.A N ALA 52.A O no hydrogen 3.099 N/A CYS 68.A N SER 77.A O no hydrogen 2.746 N/A CYS 68.A SG LEU 50.A O no hydrogen 3.921 N/A TYR 69.A N LEU 50.A O no hydrogen 2.614 N/A TYR 69.A OH ASN 74.A OD1 no hydrogen 2.665 N/A ASN 70.A N GLN 75.A O no hydrogen 3.233 N/A MET 72.A N ASN 70.A OD1 no hydrogen 3.065 N/A THR 73.A OG1 ASN 70.A O no hydrogen 3.391 N/A ASN 74.A N ASN 70.A O no hydrogen 2.706 N/A TRP 76.A NE1 ALA 32.A O no hydrogen 2.854 N/A SER 77.A N CYS 68.A O no hydrogen 2.719 N/A CYS 79.A N LEU 66.A O no hydrogen 2.863 N/A ALA 80.A N ASP 121.A OD1 no hydrogen 2.810 N/A ALA 80.A N ASP 121.A OD2 no hydrogen 3.333 N/A MET 82.A N SER 64.A O no hydrogen 2.829 N/A SER 83.A N GLU 114.A OE1 no hydrogen 2.490 N/A SER 83.A OG GLU 114.A OE1 no hydrogen 3.155 N/A SER 83.A OG GLU 114.A OE2 no hydrogen 2.834 N/A ARG 86.A N SER 63.A O no hydrogen 3.008 N/A ARG 86.A NE GLU 114.A OE2 no hydrogen 3.015 N/A ARG 86.A NH1 GLY 102.A O no hydrogen 2.778 N/A ARG 86.A NH1 SER 112.A O no hydrogen 3.002 N/A ARG 86.A NH2 SER 112.A OG no hydrogen 3.075 N/A ARG 86.A NH2 GLU 114.A OE2 no hydrogen 2.649 N/A ASN 87.A N SER 104.A O no hydrogen 2.666 N/A GLY 90.A N VAL 101.A O no hydrogen 3.218 N/A GLY 92.A N TYR 99.A O no hydrogen 3.248 N/A ILE 94.A N HIS 97.A O no hydrogen 2.889 N/A HIS 97.A N ILE 94.A O no hydrogen 2.977 N/A HIS 97.A NE2 GLU 119.A OE1 no hydrogen 2.935 N/A ILE 98.A N TYR 116.A O no hydrogen 3.172 N/A TYR 99.A N GLY 92.A O no hydrogen 2.775 N/A ALA 100.A N GLU 114.A O no hydrogen 2.779 N/A VAL 101.A N GLY 90.A O no hydrogen 2.819 N/A GLY 102.A N SER 112.A O no hydrogen 3.207 N/A GLY 103.A N ARG 133.A O no hydrogen 2.852 N/A SER 104.A N ASN 87.A O no hydrogen 2.748 N/A SER 104.A OG ASN 87.A O no hydrogen 3.408 N/A HIS 105.A N ILE 108.A O no hydrogen 3.123 N/A GLY 106.A N ASP 62.A OD2 no hydrogen 2.838 N/A ILE 108.A N HIS 105.A O no hydrogen 2.990 N/A HIS 110.A N GLY 103.A O no hydrogen 2.851 N/A HIS 110.A NE2 PRO 85.A O no hydrogen 2.799 N/A ASN 111.A ND2 MET 129.A O no hydrogen 2.805 N/A GLU 114.A N ALA 100.A O no hydrogen 3.102 N/A ARG 115.A N HIS 124.A O no hydrogen 2.921 N/A ARG 115.A NH1 TYR 99.A OH no hydrogen 3.331 N/A TYR 116.A N ILE 98.A O no hydrogen 2.802 N/A TYR 116.A OH ASP 121.A OD1 no hydrogen 2.549 N/A GLU 117.A N GLU 122.A O no hydrogen 2.899 N/A GLU 119.A N GLU 119.A OE2 no hydrogen 2.879 N/A ARG 120.A N GLU 117.A O no hydrogen 3.027 N/A TRP 123.A NE1 ALA 80.A O no hydrogen 2.737 N/A HIS 124.A N ARG 115.A O no hydrogen 2.978 N/A HIS 124.A NE2 GLU 122.A OE2 no hydrogen 2.955 N/A VAL 126.A N VAL 113.A O no hydrogen 2.821 N/A ALA 127.A N ASN 168.A OD1 no hydrogen 2.929 N/A MET 129.A N ASN 111.A O no hydrogen 2.851 N/A LEU 130.A N GLU 161.A OE1 no hydrogen 2.730 N/A THR 131.A OG1 GLU 161.A OE2 no hydrogen 3.260 N/A ARG 132.A NE.A HIS 109.A O no hydrogen 2.671 N/A ARG 133.A N HIS 110.A O no hydrogen 2.940 N/A ARG 133.A NE GLU 161.A OE2 no hydrogen 3.039 N/A ARG 133.A NH1 GLY 149.A O no hydrogen 2.972 N/A ARG 133.A NH1 SER 159.A O no hydrogen 3.122 N/A ARG 133.A NH1 SER 159.A OG no hydrogen 3.408 N/A ARG 133.A NH2 SER 159.A OG no hydrogen 3.171 N/A ARG 133.A NH2 GLU 161.A OE2 no hydrogen 2.921 N/A ILE 134.A N PHE 151.A O no hydrogen 2.826 N/A GLY 135.A N ARG 88.A O no hydrogen 2.875 N/A GLY 137.A N VAL 148.A O no hydrogen 2.843 N/A ALA 139.A N TYR 146.A O no hydrogen 3.085 N/A LEU 141.A N LEU 144.A O no hydrogen 2.786 N/A ARG 143.A NE ASP 95.A OD1 no hydrogen 3.258 N/A ARG 143.A NH1 ASP 95.A OD2 no hydrogen 1.858 N/A LEU 144.A N LEU 141.A O no hydrogen 2.826 N/A LEU 145.A N TYR 163.A O no hydrogen 3.302 N/A TYR 146.A N ALA 139.A O no hydrogen 2.754 N/A ALA 147.A N GLU 161.A O no hydrogen 2.876 N/A VAL 148.A N GLY 137.A O no hydrogen 2.737 N/A GLY 149.A N SER 159.A O no hydrogen 2.970 N/A GLY 150.A N ARG 180.A O no hydrogen 2.748 N/A PHE 151.A N ILE 134.A O no hydrogen 2.778 N/A ASP 152.A N ASN 155.A O no hydrogen 3.188 N/A THR 154.A N ASP 152.A OD1 no hydrogen 2.674 N/A ASN 155.A N ASP 152.A OD1 no hydrogen 2.757 N/A ARG 156.A NE SER 181.A OG no hydrogen 2.759 N/A LEU 157.A N GLY 150.A O no hydrogen 2.796 N/A ASN 158.A ND2 MET 176.A O no hydrogen 2.926 N/A GLU 161.A N ALA 147.A O no hydrogen 2.975 N/A CYS 162.A N ARG 171.A O no hydrogen 2.780 N/A TYR 163.A N LEU 145.A O no hydrogen 2.742 N/A TYR 163.A OH ASN 168.A OD1 no hydrogen 2.821 N/A TYR 164.A N GLU 169.A O no hydrogen 2.751 N/A ASN 168.A N PRO 165.A O no hydrogen 3.052 N/A GLU 169.A N TYR 164.A O no hydrogen 3.418 N/A TRP 170.A NE1 ALA 127.A O no hydrogen 2.843 N/A ARG 171.A N CYS 162.A O no hydrogen 2.881 N/A ILE 173.A N ALA 160.A O no hydrogen 2.856 N/A THR 174.A OG1 GLU 215.A O no hydrogen 2.714 N/A MET 176.A N ASN 158.A O no hydrogen 2.846 N/A ASN 177.A N GLU 208.A OE1 no hydrogen 2.833 N/A ASN 177.A ND2 GLU 208.A OE1 no hydrogen 3.075 N/A ASN 177.A ND2 TRP 217.A O no hydrogen 2.721 N/A THR 178.A N GLU 208.A OE2 no hydrogen 2.857 N/A ARG 180.A N LEU 157.A O no hydrogen 3.024 N/A ARG 180.A NE GLU 208.A OE2 no hydrogen 3.102 N/A ARG 180.A NH1 GLY 196.A O no hydrogen 2.752 N/A ARG 180.A NH1 SER 206.A O no hydrogen 3.005 N/A ARG 180.A NH2 SER 206.A OG no hydrogen 2.753 N/A ARG 180.A NH2 GLU 208.A OE2 no hydrogen 3.101 N/A SER 181.A N TYR 198.A O no hydrogen 3.002 N/A GLY 182.A N GLY 135.A O no hydrogen 3.002 N/A GLY 184.A N ALA 195.A O no hydrogen 2.800 N/A CYS 186.A N TYR 193.A O no hydrogen 3.096 N/A LEU 188.A N CYS 191.A O no hydrogen 2.973 N/A CYS 191.A N LEU 188.A O no hydrogen 3.070 N/A CYS 191.A SG HIS 189.A O no hydrogen 3.917 N/A ILE 192.A N TYR 210.A O no hydrogen 3.301 N/A TYR 193.A N CYS 186.A O no hydrogen 2.858 N/A ALA 194.A N GLU 208.A O no hydrogen 2.936 N/A ALA 195.A N GLY 184.A O no hydrogen 2.642 N/A GLY 196.A N SER 206.A O no hydrogen 3.090 N/A GLY 197.A N ARG 227.A O no hydrogen 2.809 N/A TYR 198.A N SER 181.A O no hydrogen 2.786 N/A ASP 199.A N ASP 202.A O no hydrogen 3.154 N/A GLN 201.A N ASP 199.A OD1 no hydrogen 2.759 N/A ASP 202.A N ASP 199.A OD1 no hydrogen 2.865 N/A GLN 203.A N ASP 202.A OD2 no hydrogen 2.608 N/A GLN 203.A N GLN 203.A OE1 no hydrogen 2.884 N/A LEU 204.A N GLY 197.A O no hydrogen 2.709 N/A GLU 208.A N ALA 194.A O no hydrogen 3.102 N/A ARG 209.A N THR 218.A O no hydrogen 2.820 N/A TYR 210.A N ILE 192.A O no hydrogen 2.775 N/A ASP 211.A N THR 216.A O no hydrogen 3.013 N/A THR 214.A N ASP 211.A OD1 no hydrogen 2.957 N/A THR 214.A OG1 ASP 211.A O no hydrogen 3.440 N/A THR 214.A OG1 ASP 211.A OD1 no hydrogen 3.099 N/A THR 214.A OG1 THR 216.A OG1 no hydrogen 3.185 N/A GLU 215.A N VAL 212.A O no hydrogen 3.057 N/A THR 216.A OG1 THR 214.A OG1 no hydrogen 3.185 N/A TRP 217.A NE1 THR 174.A O no hydrogen 3.049 N/A THR 218.A N ARG 209.A O no hydrogen 2.977 N/A VAL 220.A N VAL 207.A O no hydrogen 2.886 N/A ALA 221.A N ASP 262.A OD1 no hydrogen 2.997 N/A MET 223.A N ASN 205.A O no hydrogen 2.947 N/A LYS 224.A N GLU 255.A OE1 no hydrogen 2.659 N/A HIS 225.A N GLU 255.A OE2 no hydrogen 2.722 N/A HIS 225.A NE2 GLU 266.A OE1 no hydrogen 2.929 N/A ARG 226.A NH2 GLN 203.A O no hydrogen 2.762 N/A ARG 227.A N LEU 204.A O no hydrogen 3.103 N/A ARG 227.A NE HIS 225.A O no hydrogen 3.071 N/A ARG 227.A NH1 GLY 243.A O no hydrogen 3.000 N/A ARG 227.A NH1 SER 253.A O no hydrogen 3.053 N/A ARG 227.A NH2 SER 253.A OG no hydrogen 3.187 N/A ARG 227.A NH2 GLU 255.A OE2 no hydrogen 2.679 N/A SER 228.A N TYR 245.A O no hydrogen 2.879 N/A ALA 229.A N GLY 182.A O no hydrogen 2.804 N/A GLY 231.A N LEU 242.A O no hydrogen 2.865 N/A THR 233.A N TYR 240.A O no hydrogen 2.944 N/A HIS 235.A N ARG 238.A O no hydrogen 2.994 N/A ARG 238.A N HIS 235.A O no hydrogen 3.089 N/A ILE 239.A N TYR 257.A O no hydrogen 3.169 N/A TYR 240.A N THR 233.A O no hydrogen 2.846 N/A VAL 241.A N GLU 255.A O no hydrogen 3.089 N/A LEU 242.A N GLY 231.A O no hydrogen 2.737 N/A GLY 243.A N SER 253.A O no hydrogen 3.129 N/A GLY 244.A N ARG 274.A O no hydrogen 2.869 N/A TYR 245.A N SER 228.A O no hydrogen 2.865 N/A ASP 246.A N THR 249.A O no hydrogen 3.168 N/A HIS 248.A N ASP 246.A OD1 no hydrogen 2.901 N/A THR 249.A N ASP 246.A OD1 no hydrogen 2.779 N/A LEU 251.A N GLY 244.A O no hydrogen 2.746 N/A SER 253.A OG GLU 266.A OE2 no hydrogen 3.080 N/A VAL 254.A N THR 268.A O no hydrogen 3.078 N/A GLU 255.A N VAL 241.A O no hydrogen 3.226 N/A CYS 256.A N SER 265.A O no hydrogen 2.746 N/A CYS 256.A SG ILE 239.A O no hydrogen 3.796 N/A TYR 257.A N ILE 239.A O no hydrogen 2.927 N/A TYR 257.A OH ASP 262.A OD1 no hydrogen 2.886 N/A ASP 258.A N THR 263.A O no hydrogen 2.918 N/A ASP 260.A N ASP 258.A OD1 no hydrogen 2.919 N/A THR 261.A OG1 THR 263.A OG1 no hydrogen 3.183 N/A THR 263.A N ASP 258.A O no hydrogen 3.292 N/A THR 263.A OG1 THR 261.A OG1 no hydrogen 3.183 N/A TRP 264.A NE1 ALA 221.A O no hydrogen 2.786 N/A SER 265.A N CYS 256.A O no hydrogen 3.059 N/A VAL 267.A N VAL 254.A O no hydrogen 2.960 N/A THR 268.A OG1 ARG 269.A O no hydrogen 3.158 N/A MET 270.A N ASP 252.A O no hydrogen 2.719 N/A THR 271.A OG1 GLU 19.A OE1 no hydrogen 3.387 N/A THR 271.A OG1 GLU 19.A OE2 no hydrogen 2.824 N/A ARG 274.A N LEU 251.A O no hydrogen 2.996 N/A ARG 274.A NE SER 272.A O no hydrogen 3.236 N/A ARG 274.A NH1 GLU 19.A OE1 no hydrogen 2.861 N/A ARG 274.A NH2 GLU 19.A OE1 no hydrogen 2.659 N/A ARG 274.A NH2 SER 272.A OG no hydrogen 3.016 N/A SER 275.A N TYR 10.A O no hydrogen 2.880 N/A SER 275.A OG ALA 229.A O no hydrogen 3.349 N/A GLY 276.A N ALA 229.A O no hydrogen 3.043 N/A GLY 278.A N ALA 7.A O no hydrogen 2.949 N/A ALA 280.A N TYR 5.A O no hydrogen 3.091 N/A THR 282.A N LEU 3.A O no hydrogen 3.159 N/A