Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7xyh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N TYR 200.A OH no hydrogen 3.350 N/A SER 1.A OG TYR 200.A OH no hydrogen 3.283 N/A ARG 2.A NH1 GLU 8.A OE2 no hydrogen 3.122 N/A ALA 3.A N TYR 176.A OH no hydrogen 3.122 N/A TYR 6.A OH ASP 139.A OD1 no hydrogen 2.879 N/A VAL 9.A N TYR 6.A O no hydrogen 3.386 N/A ASN 10.A ND2 GLY 145.A O no hydrogen 3.039 N/A ASN 10.A ND2 TYR 176.A O no hydrogen 2.869 N/A SER 11.A N GLU 8.A O no hydrogen 3.044 N/A SER 11.A OG GLU 8.A O no hydrogen 2.898 N/A LEU 12.A N GLU 8.A O no hydrogen 3.368 N/A ARG 13.A N ASN 10.A O no hydrogen 3.276 N/A ARG 13.A NH1 ASN 10.A OD1 no hydrogen 3.251 N/A ARG 13.A NH2 SER 143.A O no hydrogen 2.702 N/A TYR 17.A N SER 14.A O no hydrogen 2.871 N/A TYR 17.A OH LYS 144.A O no hydrogen 2.494 N/A TRP 18.A N ARG 15.A O no hydrogen 3.146 N/A ASP 19.A N ARG 15.A O no hydrogen 2.960 N/A TYR 20.A OH GLU 174.A OE1 no hydrogen 3.267 N/A ALA 22.A N ASP 19.A O no hydrogen 3.307 N/A HIS 23.A N TYR 20.A O no hydrogen 2.828 N/A GLY 28.A N THR 94.A O no hydrogen 3.061 N/A GLN 30.A N LYS 96.A O no hydrogen 2.628 N/A VAL 36.A N GLU 49.A O no hydrogen 2.918 N/A GLY 40.A N LYS 38.A O no hydrogen 2.367 N/A VAL 47.A N GLY 40.A O no hydrogen 2.994 N/A PHE 48.A N VAL 61.A O no hydrogen 2.970 N/A GLU 49.A N ARG 37.A O no hydrogen 3.003 N/A ASN 52.A N GLU 57.A O no hydrogen 3.002 N/A ASN 52.A ND2 TYR 33.A OH no hydrogen 3.500 N/A ILE 53.A N ASP 32.A O no hydrogen 3.369 N/A ASN 55.A N ASN 52.A O no hydrogen 3.433 N/A ASN 56.A N ASN 52.A O no hydrogen 2.524 N/A VAL 59.A N ALA 50.A O no hydrogen 2.861 N/A VAL 60.A N PHE 107.A O no hydrogen 2.771 N/A VAL 61.A N PHE 48.A O no hydrogen 2.718 N/A LYS 62.A N LEU 105.A O no hydrogen 2.799 N/A LYS 62.A NZ GLU 75.A OE1 no hydrogen 2.832 N/A LYS 62.A NZ GLU 75.A OE2 no hydrogen 3.448 N/A LYS 62.A NZ ASP 169.A OD1 no hydrogen 3.051 N/A ILE 63.A N GLU 46.A O no hydrogen 3.135 N/A LEU 64.A N PRO 103.A O no hydrogen 3.275 N/A LYS 65.A NZ LYS 43.A O no hydrogen 3.130 N/A VAL 67.A N LYS 65.A O no hydrogen 2.652 N/A LYS 71.A NZ GLY 171.A O no hydrogen 3.007 N/A ILE 72.A N LYS 68.A O no hydrogen 3.371 N/A LYS 73.A N LYS 69.A O no hydrogen 3.006 N/A LYS 73.A NZ GLU 21.A O no hydrogen 3.539 N/A LYS 73.A NZ HIS 23.A O no hydrogen 2.311 N/A ARG 74.A N LYS 70.A O no hydrogen 2.948 N/A ARG 74.A NH1 GLU 174.A OE1 no hydrogen 3.450 N/A ARG 74.A NH2 GLY 171.A O no hydrogen 3.187 N/A GLU 75.A N LYS 71.A O no hydrogen 3.202 N/A VAL 76.A N ILE 72.A O no hydrogen 3.046 N/A LYS 77.A N LYS 73.A O no hydrogen 2.805 N/A LYS 77.A NZ GLU 80.A OE1 no hydrogen 2.919 N/A ILE 78.A N ARG 74.A O no hydrogen 3.037 N/A LEU 79.A N GLU 75.A O no hydrogen 2.936 N/A GLU 80.A N VAL 76.A O no hydrogen 2.901 N/A ASN 81.A N LYS 77.A O no hydrogen 2.962 N/A ASN 81.A ND2 TYR 17.A O no hydrogen 3.108 N/A LEU 82.A N ILE 78.A O no hydrogen 2.971 N/A LEU 82.A N LEU 79.A O no hydrogen 3.056 N/A ARG 83.A N GLU 80.A O no hydrogen 3.348 N/A GLY 85.A N LEU 82.A O no hydrogen 2.959 N/A ASN 87.A ND2 GLU 133.A O no hydrogen 2.801 N/A ASN 87.A ND2 GLU 133.A OE1 no hydrogen 3.294 N/A ILE 88.A N GLY 85.A O no hydrogen 3.021 N/A ILE 89.A N LEU 167.A O no hydrogen 3.200 N/A LYS 90.A N GLU 108.A OE2 no hydrogen 3.005 N/A ILE 92.A N VAL 106.A O no hydrogen 2.787 N/A ASP 93.A N VAL 106.A O no hydrogen 3.468 N/A THR 94.A OG1 SER 26.A O no hydrogen 2.858 N/A VAL 95.A N ALA 104.A O no hydrogen 2.856 N/A LYS 96.A N GLY 28.A O no hydrogen 3.124 N/A ASP 97.A N THR 102.A O no hydrogen 3.172 N/A SER 100.A N ASP 97.A O no hydrogen 3.011 N/A SER 100.A N ASP 97.A OD1 no hydrogen 2.574 N/A LYS 101.A N ASP 97.A O no hydrogen 2.361 N/A THR 102.A N SER 100.A OG no hydrogen 3.319 N/A LEU 105.A N LYS 62.A O no hydrogen 2.819 N/A VAL 106.A N ASP 93.A O no hydrogen 2.934 N/A PHE 107.A N VAL 60.A O no hydrogen 2.650 N/A GLU 108.A N LYS 90.A O no hydrogen 3.089 N/A THR 113.A N ILE 158.A O no hydrogen 2.968 N/A THR 113.A OG1 ILE 158.A O no hydrogen 3.487 N/A LYS 116.A N ASP 114.A OD2 no hydrogen 3.445 N/A LYS 116.A NZ GLU 224.A OE1 no hydrogen 2.945 N/A GLN 117.A N ASP 114.A O no hydrogen 2.845 N/A LEU 118.A N ASP 114.A O no hydrogen 2.843 N/A TYR 119.A N PHE 115.A O no hydrogen 2.952 N/A ILE 121.A N LEU 118.A O no hydrogen 3.235 N/A THR 123.A N ASP 126.A OD2 no hydrogen 3.330 N/A ASP 126.A N THR 123.A OG1 no hydrogen 3.056 N/A ILE 127.A N THR 123.A O no hydrogen 3.029 N/A ARG 128.A N ASP 124.A O no hydrogen 3.348 N/A ARG 128.A NE ASP 124.A OD1 no hydrogen 2.985 N/A ARG 128.A NE ASP 124.A OD2 no hydrogen 3.349 N/A ARG 128.A NH1 TYR 317.A O no hydrogen 2.835 N/A ARG 128.A NH2 ASP 124.A OD1 no hydrogen 3.309 N/A ARG 128.A NH2 ASP 124.A OD2 no hydrogen 3.190 N/A PHE 129.A N PHE 125.A O no hydrogen 2.838 N/A TYR 130.A N ASP 126.A O no hydrogen 2.872 N/A TYR 130.A OH HIS 160.A ND1 no hydrogen 3.016 N/A MET 131.A N ILE 127.A O no hydrogen 3.115 N/A TYR 132.A N ARG 128.A O no hydrogen 3.001 N/A GLU 133.A N PHE 129.A O no hydrogen 3.167 N/A LEU 134.A N TYR 130.A O no hydrogen 2.795 N/A LEU 135.A N MET 131.A O no hydrogen 2.841 N/A LYS 136.A N TYR 132.A O no hydrogen 2.923 N/A LYS 136.A NZ GLU 133.A OE2 no hydrogen 2.953 N/A LYS 136.A NZ GLN 325.A OE1 no hydrogen 2.786 N/A ALA 137.A N GLU 133.A O no hydrogen 3.271 N/A LEU 138.A N LEU 134.A O no hydrogen 3.059 N/A ASP 139.A N LEU 135.A O no hydrogen 2.797 N/A TYR 140.A N LYS 136.A O no hydrogen 3.118 N/A CYS 141.A N ALA 137.A O no hydrogen 3.170 N/A CYS 141.A SG ALA 137.A O no hydrogen 4.029 N/A CYS 141.A SG LEU 138.A O no hydrogen 3.653 N/A CYS 141.A SG ILE 146.A O no hydrogen 3.614 N/A HIS 142.A N LEU 138.A O no hydrogen 3.064 N/A HIS 142.A NE2 ASP 208.A OD2 no hydrogen 2.844 N/A SER 143.A N ASP 139.A O no hydrogen 3.156 N/A SER 143.A OG ASP 139.A O no hydrogen 3.020 N/A SER 143.A OG TYR 140.A O no hydrogen 2.648 N/A LYS 144.A N TYR 140.A O no hydrogen 2.907 N/A GLY 145.A N HIS 142.A O no hydrogen 2.785 N/A ILE 146.A N CYS 141.A O no hydrogen 2.871 N/A MET 147.A N GLU 174.A O no hydrogen 2.864 N/A HIS 148.A N ASP 208.A OD2 no hydrogen 3.033 N/A HIS 148.A NE2 ILE 168.A O no hydrogen 2.759 N/A ARG 149.A N ASP 208.A OD1 no hydrogen 2.875 N/A ARG 149.A NE LEU 172.A O no hydrogen 2.495 N/A ARG 149.A NH1 TYR 203.A OH no hydrogen 3.082 N/A ARG 149.A NH2 LEU 172.A O no hydrogen 2.693 N/A ASP 150.A N HIS 148.A ND1 no hydrogen 3.010 N/A ASN 155.A N LYS 152.A O no hydrogen 2.917 N/A ASN 155.A ND2 ASP 150.A O no hydrogen 2.905 N/A ASN 155.A ND2 ASP 150.A OD2 no hydrogen 3.287 N/A VAL 156.A N PRO 153.A O no hydrogen 3.136 N/A MET 157.A N ARG 166.A O no hydrogen 2.819 N/A ASP 159.A N LYS 164.A O no hydrogen 2.816 N/A GLN 161.A N ASP 159.A OD1 no hydrogen 3.236 N/A GLN 162.A N ASP 159.A OD1 no hydrogen 3.238 N/A LYS 163.A N HIS 160.A O no hydrogen 3.174 N/A LYS 164.A N ASP 159.A O no hydrogen 2.991 N/A ARG 166.A N MET 157.A O no hydrogen 2.772 N/A ARG 166.A NE GLU 108.A OE2 no hydrogen 3.155 N/A ARG 166.A NH1 LEU 165.A O no hydrogen 2.934 N/A LEU 167.A N ASN 87.A O no hydrogen 3.145 N/A ILE 168.A N ASN 155.A O no hydrogen 3.124 N/A ALA 173.A N TRP 170.A O no hydrogen 2.975 N/A GLU 174.A N MET 147.A O no hydrogen 2.953 N/A PHE 175.A N GLU 174.A OE2 no hydrogen 2.451 N/A TYR 176.A N GLY 145.A O no hydrogen 2.781 N/A HIS 177.A N TYR 182.A OH no hydrogen 2.868 N/A GLN 180.A N HIS 177.A O no hydrogen 3.244 N/A TYR 182.A N GLN 201.A O no hydrogen 2.766 N/A TYR 182.A OH PHE 175.A O no hydrogen 2.757 N/A ARG 185.A N ASN 183.A OD1 no hydrogen 2.613 N/A ARG 185.A NE ASN 183.A OD1 no hydrogen 3.102 N/A ARG 189.A NH1 GLY 229.A O no hydrogen 3.005 N/A PHE 191.A N SER 188.A O no hydrogen 3.039 N/A LYS 192.A N ARG 189.A O no hydrogen 3.301 N/A LYS 192.A NZ VAL 186.A O no hydrogen 3.043 N/A LYS 192.A NZ ALA 187.A O no hydrogen 3.307 N/A GLU 195.A N GLU 195.A OE1 no hydrogen 2.528 N/A LEU 197.A N GLY 193.A O no hydrogen 3.299 N/A VAL 198.A N PRO 194.A O no hydrogen 2.881 N/A VAL 198.A N GLU 195.A O no hydrogen 3.272 N/A ASP 199.A N LEU 196.A O no hydrogen 3.132 N/A TYR 200.A N GLU 195.A O no hydrogen 2.929 N/A GLN 201.A NE2 TYR 182.A O no hydrogen 3.200 N/A TYR 203.A OH ASN 183.A O no hydrogen 2.480 N/A TYR 205.A OH TYR 6.A O no hydrogen 2.832 N/A SER 206.A N ASP 204.A OD1 no hydrogen 2.716 N/A SER 206.A OG ASP 204.A OD1 no hydrogen 2.913 N/A SER 206.A OG ASP 204.A OD2 no hydrogen 3.381 N/A SER 206.A OG HIS 303.A O no hydrogen 3.406 N/A LEU 207.A N ASP 204.A O no hydrogen 3.194 N/A TRP 210.A N SER 206.A O no hydrogen 3.214 N/A SER 211.A N LEU 207.A O no hydrogen 3.059 N/A SER 211.A OG PHE 191.A O no hydrogen 2.700 N/A LEU 212.A N ASP 208.A O no hydrogen 2.853 N/A GLY 213.A N MET 209.A O no hydrogen 2.966 N/A CYS 214.A N TRP 210.A O no hydrogen 2.944 N/A CYS 214.A SG TYR 190.A O no hydrogen 3.829 N/A CYS 214.A SG TRP 210.A O no hydrogen 3.463 N/A MET 215.A N SER 211.A O no hydrogen 3.070 N/A LEU 216.A N LEU 212.A O no hydrogen 2.915 N/A ALA 217.A N GLY 213.A O no hydrogen 2.877 N/A SER 218.A N CYS 214.A O no hydrogen 3.098 N/A SER 218.A OG MET 215.A O no hydrogen 2.941 N/A MET 219.A N MET 215.A O no hydrogen 3.035 N/A MET 219.A N LEU 216.A O no hydrogen 3.050 N/A ILE 220.A N LEU 216.A O no hydrogen 3.016 N/A PHE 221.A N ALA 217.A O no hydrogen 3.010 N/A ARG 222.A NH2 GLN 120.A O no hydrogen 2.892 N/A ARG 223.A NE PHE 226.A O no hydrogen 3.003 N/A ARG 223.A NH2 PHE 226.A O no hydrogen 3.118 N/A GLY 229.A N PHE 227.A O no hydrogen 3.223 N/A GLN 230.A N ASP 234.A OD2 no hydrogen 3.025 N/A TYR 233.A OH ASP 260.A OD2 no hydrogen 2.796 N/A ASP 234.A N ASP 231.A OD1 no hydrogen 2.573 N/A GLN 235.A N ASP 231.A O no hydrogen 2.868 N/A GLN 235.A NE2 PHE 227.A O no hydrogen 3.102 N/A LEU 236.A N ASN 232.A O no hydrogen 3.367 N/A VAL 237.A N TYR 233.A O no hydrogen 3.142 N/A ARG 238.A N ASP 234.A O no hydrogen 2.768 N/A ARG 238.A NE ASP 234.A OD1 no hydrogen 3.386 N/A ARG 238.A NE ASP 234.A OD2 no hydrogen 2.858 N/A ARG 238.A NH2 ASP 234.A OD2 no hydrogen 3.237 N/A ILE 239.A N GLN 235.A O no hydrogen 3.060 N/A ALA 240.A N LEU 236.A O no hydrogen 2.989 N/A LYS 241.A N VAL 237.A O no hydrogen 3.081 N/A LYS 241.A N ARG 238.A O no hydrogen 3.290 N/A VAL 242.A N ILE 239.A O no hydrogen 3.021 N/A LEU 243.A N ILE 239.A O no hydrogen 2.926 N/A THR 245.A N HIS 270.A O no hydrogen 2.910 N/A THR 245.A OG1 HIS 270.A O no hydrogen 3.022 N/A GLU 247.A N GLU 247.A OE1 no hydrogen 2.472 N/A LEU 248.A N THR 245.A O no hydrogen 3.296 N/A TYR 249.A N THR 245.A O no hydrogen 3.199 N/A GLY 250.A N GLU 246.A O no hydrogen 3.093 N/A TYR 251.A OH HIS 303.A ND1 no hydrogen 3.321 N/A LEU 252.A N LEU 248.A O no hydrogen 3.074 N/A LYS 253.A N TYR 249.A O no hydrogen 2.894 N/A LYS 254.A N GLY 250.A O no hydrogen 2.946 N/A LYS 254.A NZ ASP 302.A OD2 no hydrogen 2.858 N/A TYR 255.A N TYR 251.A O no hydrogen 3.060 N/A TYR 255.A OH ASP 302.A OD1 no hydrogen 2.749 N/A HIS 256.A N LYS 253.A O no hydrogen 2.888 N/A ILE 257.A N LEU 252.A O no hydrogen 2.806 N/A HIS 262.A N ASP 260.A OD1 no hydrogen 2.969 N/A HIS 262.A ND1 ASP 260.A OD1 no hydrogen 2.889 N/A PHE 263.A N ASP 260.A O no hydrogen 3.083 N/A ILE 266.A N PHE 263.A O no hydrogen 3.136 N/A LEU 267.A N PHE 263.A O no hydrogen 2.843 N/A HIS 270.A N THR 245.A OG1 no hydrogen 2.772 N/A LYS 273.A N VAL 242.A O no hydrogen 2.744 N/A LYS 273.A NZ LYS 241.A O no hydrogen 2.627 N/A LYS 273.A NZ SER 271.A O no hydrogen 2.694 N/A TRP 275.A NE1 ASP 296.A OD1 no hydrogen 2.621 N/A GLU 276.A N GLU 276.A OE1 no hydrogen 2.557 N/A ASN 277.A N ARG 274.A O no hydrogen 2.828 N/A ILE 279.A N GLU 276.A O no hydrogen 2.972 N/A HIS 280.A N ASN 283.A OD1 no hydrogen 3.184 N/A HIS 280.A NE2 GLU 282.A OE1 no hydrogen 2.955 N/A ASN 283.A N HIS 280.A O no hydrogen 2.989 N/A ASN 283.A ND2 PHE 221.A O no hydrogen 3.157 N/A ASN 283.A ND2 PHE 278.A O no hydrogen 3.160 N/A LEU 286.A N ASN 283.A O no hydrogen 3.027 N/A VAL 287.A N ARG 284.A O no hydrogen 3.312 N/A ALA 291.A N SER 288.A O no hydrogen 2.920 N/A LEU 292.A N SER 288.A O no hydrogen 3.126 N/A ASP 293.A N PRO 289.A O no hydrogen 3.008 N/A LEU 294.A N GLU 290.A O no hydrogen 3.232 N/A LEU 295.A N ALA 291.A O no hydrogen 3.089 N/A ASP 296.A N LEU 292.A O no hydrogen 2.982 N/A LYS 297.A N ASP 293.A O no hydrogen 3.110 N/A LYS 297.A NZ ASP 293.A OD1 no hydrogen 3.351 N/A LYS 297.A NZ ASP 293.A OD2 no hydrogen 3.086 N/A LEU 298.A N LEU 295.A O no hydrogen 2.931 N/A LEU 299.A N LEU 295.A O no hydrogen 3.014 N/A ARG 300.A N LEU 298.A O no hydrogen 3.187 N/A ARG 300.A NE ASP 296.A O no hydrogen 3.579 N/A TYR 301.A OH GLY 244.A O no hydrogen 3.014 N/A HIS 303.A ND1 TYR 251.A OH no hydrogen 3.321 N/A GLN 304.A N ASP 302.A OD1 no hydrogen 2.924 N/A GLN 305.A N ASP 302.A O no hydrogen 2.807 N/A ARG 306.A N HIS 303.A O no hydrogen 3.260 N/A ARG 306.A NE ARG 300.A O no hydrogen 2.982 N/A ARG 306.A NH1 GLU 195.A OE1 no hydrogen 3.272 N/A ARG 306.A NH1 GLU 195.A OE2 no hydrogen 2.510 N/A ARG 306.A NH1 SER 206.A O no hydrogen 3.313 N/A ARG 306.A NH2 GLU 195.A OE1 no hydrogen 2.868 N/A ARG 306.A NH2 ARG 300.A O no hydrogen 3.286 N/A ARG 306.A NH2 TYR 301.A O no hydrogen 2.778 N/A LEU 307.A N LYS 297.A O no hydrogen 3.119 N/A THR 308.A N GLU 311.A OE1 no hydrogen 2.884 N/A THR 308.A OG1 GLU 311.A OE1 no hydrogen 3.295 N/A GLU 311.A N THR 308.A OG1 no hydrogen 3.116 N/A ALA 312.A N THR 308.A O no hydrogen 2.951 N/A MET 313.A N ALA 309.A O no hydrogen 2.969 N/A GLU 314.A N LYS 310.A O no hydrogen 3.236 N/A GLU 314.A N GLU 311.A O no hydrogen 2.997 N/A HIS 315.A N ALA 312.A O no hydrogen 2.911 N/A HIS 315.A NE2 ASP 293.A OD2 no hydrogen 2.849 N/A TYR 317.A N HIS 315.A ND1 no hydrogen 3.079 N/A PHE 318.A N HIS 315.A O no hydrogen 2.816 N/A TYR 319.A N PRO 316.A O no hydrogen 3.013 N/A VAL 321.A N PHE 318.A O no hydrogen 2.564 N/A VAL 322.A N PHE 318.A O no hydrogen 3.123 N/A LYS 323.A N TYR 319.A O no hydrogen 3.353 N/A GLN 325.A N VAL 322.A O no hydrogen 3.094 N/A GLN 325.A NE2 VAL 321.A O no hydrogen 3.593 N/A