Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7yq4_E.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 6.A N ASN 25.A O no hydrogen 3.335 N/A MET 11.A N HIS 32.A O no hydrogen 3.284 N/A ASN 15.A N LEU 37.A O no hydrogen 3.211 N/A LEU 20.A N LEU 17.A O no hydrogen 3.215 N/A HIS 21.A N THR 18.A O no hydrogen 3.509 N/A HIS 21.A ND1 THR 18.A O no hydrogen 2.869 N/A LEU 23.A N LEU 20.A O no hydrogen 3.353 N/A CYS 26.A SG GLU 22.A O no hydrogen 3.958 N/A SER 27.A N GLU 6.A O no hydrogen 3.279 N/A ILE 29.A N MET 56.A O no hydrogen 3.311 N/A LEU 33.A N TYR 60.A O no hydrogen 3.476 N/A GLN 34.A N MET 11.A O no hydrogen 3.289 N/A ILE 35.A N LEU 62.A O no hydrogen 3.023 N/A LEU 36.A N ILE 13.A O no hydrogen 3.051 N/A LEU 37.A N PHE 64.A O no hydrogen 3.286 N/A MET 38.A N ARG 65.A O no hydrogen 3.242 N/A THR 41.A N PHE 39.A O no hydrogen 2.994 N/A SER 50.A OG ASP 74.A O no hydrogen 2.936 N/A PHE 51.A N LEU 75.A O no hydrogen 3.197 N/A ILE 55.A N SER 27.A O no hydrogen 3.325 N/A ILE 57.A N VAL 81.A O no hydrogen 3.426 N/A THR 58.A N ILE 29.A O no hydrogen 3.110 N/A THR 58.A OG1 ILE 29.A O no hydrogen 3.376 N/A THR 58.A OG1 GLY 31.A O no hydrogen 3.474 N/A TYR 60.A OH GLN 34.A OE1 no hydrogen 3.380 N/A LEU 62.A N LEU 33.A O no hydrogen 3.302 N/A LEU 63.A N VAL 94.A O no hydrogen 3.302 N/A PHE 64.A N ILE 35.A O no hydrogen 3.276 N/A ARG 65.A N GLU 97.A O no hydrogen 3.262 N/A LEU 75.A N LEU 72.A O no hydrogen 3.141 N/A PHE 76.A N LEU 72.A O no hydrogen 3.150 N/A ASN 78.A ND2 PRO 52.A O no hydrogen 3.597 N/A THR 80.A N ILE 55.A O no hydrogen 2.919 N/A ARG 83.A N ILE 57.A O no hydrogen 3.136 N/A GLY 84.A N THR 58.A O no hydrogen 2.467 N/A SER 85.A N THR 58.A O no hydrogen 3.344 N/A ARG 86.A N ASP 59.A OD1 no hydrogen 3.078 N/A PHE 88.A N TYR 91.A O no hydrogen 3.036 N/A PHE 89.A N THR 317.A OG1 no hydrogen 2.532 N/A TYR 91.A N PHE 88.A O no hydrogen 3.154 N/A ALA 92.A N SER 116.A O no hydrogen 2.582 N/A LEU 93.A N SER 116.A O no hydrogen 3.423 N/A VAL 94.A N LEU 61.A O no hydrogen 3.193 N/A ILE 95.A N ARG 118.A O no hydrogen 3.329 N/A PHE 96.A N LEU 63.A O no hydrogen 3.081 N/A GLU 97.A N GLU 120.A O no hydrogen 3.365 N/A LYS 102.A N GLU 70.A O no hydrogen 2.668 N/A GLU 103.A N GLU 70.A O no hydrogen 3.279 N/A ASN 108.A ND2 ASN 78.A OD1 no hydrogen 2.730 N/A MET 110.A N THR 80.A O no hydrogen 2.764 N/A ASN 111.A N THR 80.A O no hydrogen 3.466 N/A ILE 112.A N ILE 136.A O no hydrogen 3.412 N/A THR 113.A N ILE 82.A O no hydrogen 3.403 N/A ARG 114.A N ARG 83.A O no hydrogen 3.172 N/A ARG 114.A NE GLU 345.A OE1 no hydrogen 2.768 N/A ARG 114.A NH2 GLN 320.A OE1 no hydrogen 3.174 N/A ARG 114.A NH2 GLU 345.A OE1 no hydrogen 2.766 N/A VAL 117.A N ASN 143.A OD1 no hydrogen 3.017 N/A ARG 118.A N LEU 93.A O no hydrogen 3.086 N/A ARG 118.A NH1 TYR 91.A OH no hydrogen 3.454 N/A GLU 120.A N ILE 95.A O no hydrogen 3.067 N/A CYS 126.A N LYS 102.A O no hydrogen 2.960 N/A CYS 126.A SG GLU 124.A O no hydrogen 3.967 N/A LEU 128.A N ASP 150.A OD2 no hydrogen 2.955 N/A THR 130.A OG1 THR 130.A O no hydrogen 2.434 N/A THR 130.A OG1 GLU 172.A O no hydrogen 3.440 N/A THR 130.A OG1 CYS 174.A O no hydrogen 2.958 N/A ARG 135.A N ASP 132.A O no hydrogen 3.497 N/A ARG 135.A NH1 ARG 135.A O no hydrogen 3.197 N/A ARG 135.A NH2 LYS 189.A O no hydrogen 3.134 N/A ILE 136.A N TRP 133.A O no hydrogen 3.002 N/A LEU 137.A N TRP 133.A O no hydrogen 3.329 N/A ASN 148.A ND2 ILE 119.A O no hydrogen 3.484 N/A ASN 152.A ND2 GLU 154.A OE2 no hydrogen 2.769 N/A CYS 155.A SG ASP 150.A OD1 no hydrogen 3.202 N/A ASP 157.A N CYS 155.A O no hydrogen 3.025 N/A CYS 159.A SG PRO 160.A O no hydrogen 3.305 N/A CYS 161.A N GLN 181.A O no hydrogen 2.524 N/A THR 164.A OG1 ASP 132.A OD2 no hydrogen 3.205 N/A ARG 173.A N GLU 172.A OE1 no hydrogen 3.142 N/A CYS 174.A N THR 130.A O no hydrogen 2.957 N/A CYS 174.A N THR 130.A OG1 no hydrogen 2.552 N/A TRP 175.A N HIS 179.A O no hydrogen 3.104 N/A THR 176.A N HIS 179.A O no hydrogen 3.257 N/A GLN 181.A NE2 ILE 131.A O no hydrogen 3.110 N/A LYS 182.A NZ ASN 207.A OD1 no hydrogen 2.532 N/A THR 186.A OG1 THR 186.A O no hydrogen 2.392 N/A CYS 188.A SG GLY 192.A O no hydrogen 4.019 N/A HIS 191.A ND1 SER 202.A O no hydrogen 2.446 N/A CYS 193.A SG THR 194.A O no hydrogen 3.269 N/A THR 194.A OG1 LEU 198.A O no hydrogen 3.012 N/A GLU 196.A N GLU 196.A OE1 no hydrogen 2.733 N/A CYS 199.A SG CYS 200.A O no hydrogen 3.848 N/A GLU 203.A N HIS 201.A ND1 no hydrogen 3.354 N/A CYS 204.A SG GLU 203.A O no hydrogen 3.192 N/A LEU 205.A N ALA 219.A O no hydrogen 3.029 N/A ASN 207.A ND2 ASN 108.A OD1 no hydrogen 3.632 N/A CYS 208.A SG ASN 207.A O no hydrogen 3.273 N/A SER 209.A OG GLN 210.A OE1 no hydrogen 3.452 N/A SER 209.A OG LYS 216.A O no hydrogen 2.511 N/A THR 215.A N ASP 213.A OD1 no hydrogen 3.116 N/A THR 215.A OG1 ASP 213.A OD1 no hydrogen 3.370 N/A LYS 216.A NZ ASP 213.A OD2 no hydrogen 3.002 N/A CYS 220.A SG PHE 223.A O no hydrogen 3.261 N/A ARG 228.A N LEU 225.A O no hydrogen 3.001 N/A ARG 228.A NH1 ASP 226.A OD2 no hydrogen 2.856 N/A ARG 228.A NH2 ASP 226.A OD2 no hydrogen 3.082 N/A CYS 229.A SG GLU 203.A O no hydrogen 3.911 N/A TYR 237.A N PRO 234.A O no hydrogen 2.820 N/A HIS 239.A N ASN 274.A O no hydrogen 3.010 N/A TRP 243.A N PHE 240.A O no hydrogen 3.237 N/A TRP 243.A NE1 GLU 30.A OE2 no hydrogen 3.049 N/A ARG 244.A N PHE 240.A O no hydrogen 3.115 N/A CYS 245.A SG TYR 224.A O no hydrogen 3.827 N/A CYS 245.A SG ARG 244.A O no hydrogen 3.257 N/A VAL 246.A N TYR 238.A O no hydrogen 3.422 N/A SER 249.A OG ASN 247.A OD1 no hydrogen 2.486 N/A HIS 255.A N GLN 252.A O no hydrogen 3.177 N/A HIS 255.A NE2 TYR 269.A O no hydrogen 2.426 N/A HIS 256.A N ASP 253.A O no hydrogen 3.201 N/A LYS 257.A NZ ASP 253.A O no hydrogen 3.459 N/A LYS 257.A NZ ASP 253.A OD2 no hydrogen 2.598 N/A CYS 258.A SG LEU 254.A O no hydrogen 3.620 N/A LYS 259.A N HIS 255.A O no hydrogen 2.837 N/A LYS 259.A NZ ASN 260.A OD1 no hydrogen 3.421 N/A ARG 262.A N ASN 260.A O no hydrogen 2.681 N/A CYS 266.A SG HIS 267.A O no hydrogen 3.970 N/A GLN 268.A N GLN 268.A OE1 no hydrogen 2.810 N/A VAL 270.A N ILE 277.A O no hydrogen 3.031 N/A HIS 272.A N LYS 275.A O no hydrogen 3.034 N/A LYS 275.A N HIS 272.A O no hydrogen 3.052 N/A CYS 276.A N HIS 239.A O no hydrogen 3.234 N/A ILE 277.A N VAL 270.A O no hydrogen 3.291 N/A GLY 283.A N CYS 300.A O no hydrogen 2.980 N/A CYS 293.A SG ILE 271.A O no hydrogen 3.888 N/A THR 294.A N THR 285.A O no hydrogen 3.529 N/A THR 294.A OG1 THR 285.A O no hydrogen 3.492 N/A CYS 296.A SG LEU 297.A O no hydrogen 3.734 N/A CYS 304.A N VAL 327.A O no hydrogen 3.022 N/A SER 315.A OG ASN 90.A OD1 no hydrogen 2.990 N/A SER 315.A OG ASP 314.A O no hydrogen 2.739 N/A SER 318.A N SER 315.A O no hydrogen 3.252 N/A ALA 319.A N SER 315.A O no hydrogen 3.009 N/A CYS 325.A SG LEU 322.A O no hydrogen 3.597 N/A THR 326.A N LYS 302.A O no hydrogen 3.387 N/A ILE 328.A N GLU 355.A O no hydrogen 3.092 N/A SER 331.A OG TYR 359.A O no hydrogen 2.309 N/A LEU 332.A N TYR 359.A O no hydrogen 3.327 N/A ILE 333.A N LYS 311.A O no hydrogen 3.174 N/A ILE 334.A N LYS 361.A O no hydrogen 2.772 N/A ASN 335.A N ILE 313.A O no hydrogen 3.302 N/A ASN 341.A N ASN 340.A OD1 no hydrogen 2.516 N/A GLU 354.A N THR 326.A O no hydrogen 2.896 N/A ILE 356.A N LEU 379.A O no hydrogen 3.520 N/A SER 357.A N ILE 328.A O no hydrogen 3.246 N/A TYR 359.A N SER 331.A OG no hydrogen 2.964 N/A LEU 360.A N SER 391.A O no hydrogen 3.102 N/A ILE 362.A N TYR 393.A O no hydrogen 3.079 N/A ARG 363.A N ILE 334.A O no hydrogen 3.359 N/A ARG 364.A N LEU 395.A O no hydrogen 2.989 N/A TYR 366.A N ILE 336.A O no hydrogen 3.425 N/A LEU 371.A N GLN 402.A O no hydrogen 3.140 N/A ARG 375.A NH2 GLU 347.A OE1 no hydrogen 3.378 N/A ARG 378.A N GLU 354.A O no hydrogen 3.245 N/A ARG 381.A N ILE 356.A O no hydrogen 3.067 N/A THR 384.A OG1 LEU 385.A O no hydrogen 3.354 N/A GLU 386.A N TYR 390.A O no hydrogen 3.082 N/A ASN 389.A N GLU 386.A O no hydrogen 3.379 N/A SER 391.A N LYS 417.A O no hydrogen 3.338 N/A SER 391.A OG GLN 415.A O no hydrogen 3.243 N/A LEU 395.A N ILE 362.A O no hydrogen 2.970 N/A ASP 396.A N HIS 421.A O no hydrogen 3.443 N/A ASN 397.A ND2 ILE 362.A O no hydrogen 3.532 N/A ASN 397.A ND2 SER 365.A O no hydrogen 3.265 N/A GLN 398.A NE2 ASP 396.A O no hydrogen 3.498 N/A THR 412.A N ARG 378.A O no hydrogen 3.153 N/A THR 412.A OG1 THR 412.A O no hydrogen 2.536 N/A THR 413.A OG1 GLN 415.A O no hydrogen 3.449 N/A THR 414.A OG1 ARG 381.A O no hydrogen 2.702 N/A GLN 415.A NE2 GLY 382.A O no hydrogen 2.386 N/A GLN 415.A NE2 THR 384.A O no hydrogen 3.519 N/A LEU 426.A N ASN 423.A O no hydrogen 3.239 N/A HIS 432.A N LEU 428.A O no hydrogen 3.014 N/A LYS 433.A N SER 429.A O no hydrogen 3.260 N/A GLU 435.A N HIS 432.A O no hydrogen 3.061 N/A VAL 437.A N LYS 433.A O no hydrogen 3.345 N/A SER 438.A N MET 434.A O no hydrogen 3.185 N/A SER 438.A OG MET 434.A O no hydrogen 3.033 N/A SER 438.A OG GLU 435.A O no hydrogen 3.396 N/A SER 438.A OG THR 440.A O no hydrogen 3.135 N/A LYS 441.A NZ GLY 439.A O no hydrogen 3.501 N/A ARG 443.A NH1 THR 414.A O no hydrogen 3.289 N/A ARG 443.A NH2 GLY 416.A O no hydrogen 2.491 N/A ALA 450.A N PHE 420.A O no hydrogen 3.331 N/A GLY 455.A N ASN 423.A O no hydrogen 3.063 N/A LYS 457.A N PRO 424.A O no hydrogen 3.292 N/A GLU 463.A N ASN 462.A OD1 no hydrogen 2.592 N/A SER 468.A N ARG 480.A O no hydrogen 2.881 N/A SER 468.A OG ARG 480.A O no hydrogen 2.759 N/A TYR 469.A N ARG 480.A O no hydrogen 3.387 N/A ARG 471.A N LEU 478.A O no hydrogen 3.352 N/A SER 473.A N LYS 476.A O no hydrogen 2.788 N/A LEU 478.A N ARG 471.A O no hydrogen 2.892 N/A ARG 480.A NE LEU 479.A O no hydrogen 3.210 N/A GLU 482.A N LYS 466.A O no hydrogen 3.455 N/A ARG 490.A N ASP 488.A OD1 no hydrogen 2.828 N/A ARG 490.A NE ASP 488.A OD1 no hydrogen 3.122 N/A ARG 490.A NH2 ASP 488.A OD1 no hydrogen 3.394 N/A ARG 490.A NH2 ASP 488.A OD2 no hydrogen 2.962 N/A ASP 491.A N ASP 488.A O no hydrogen 3.291 N/A LEU 492.A N ARG 490.A O no hydrogen 2.821 N/A LEU 493.A N LEU 561.A O no hydrogen 3.196 N/A MET 496.A N LYS 559.A O no hydrogen 2.842 N/A LEU 497.A N VAL 524.A O no hydrogen 3.072 N/A PHE 498.A N PHE 557.A O no hydrogen 3.301 N/A TYR 499.A N TRP 521.A O no hydrogen 3.310 N/A LYS 500.A N ALA 555.A O no hydrogen 3.314 N/A ALA 502.A N GLN 553.A O no hydrogen 3.178 N/A THR 508.A OG1 GLU 509.A O no hydrogen 3.335 N/A GLN 513.A NE2 ASN 519.A OD1 no hydrogen 2.713 N/A SER 520.A OG GLY 517.A O no hydrogen 3.109 N/A THR 522.A OG1 TYR 499.A O no hydrogen 3.089 N/A THR 522.A OG1 TRP 521.A O no hydrogen 2.717 N/A THR 522.A OG1 THR 522.A O no hydrogen 2.464 N/A VAL 524.A N LEU 497.A O no hydrogen 3.055 N/A SER 532.A OG ASP 534.A O no hydrogen 2.951 N/A ASP 534.A N SER 532.A OG no hydrogen 3.370 N/A ASN 539.A N SER 537.A OG no hydrogen 2.961 N/A ASN 539.A ND2 LEU 530.A O no hydrogen 2.405 N/A MET 545.A N ILE 477.A O no hydrogen 3.454 N/A LEU 548.A N ASP 475.A OD1 no hydrogen 3.186 N/A LYS 549.A NZ GLU 501.A OE2 no hydrogen 3.210 N/A TRP 551.A N ASP 583.A O no hydrogen 3.137 N/A THR 552.A OG1 GLU 501.A OE1 no hydrogen 3.422 N/A TYR 554.A N VAL 580.A O no hydrogen 3.026 N/A ALA 555.A N LYS 500.A O no hydrogen 3.095 N/A LYS 559.A N MET 496.A O no hydrogen 3.144 N/A THR 560.A N ALA 573.A O no hydrogen 3.321 N/A THR 560.A OG1 GLY 494.A O no hydrogen 3.270 N/A THR 563.A OG1 ASP 491.A OD1 no hydrogen 2.325 N/A ARG 568.A NE HIS 432.A ND1 no hydrogen 3.453 N/A THR 570.A OG1 ARG 569.A O no hydrogen 2.651 N/A LYS 574.A N GLU 463.A O no hydrogen 3.342 N/A LYS 574.A NZ GLU 509.A OE1 no hydrogen 2.464 N/A SER 575.A N VAL 558.A O no hydrogen 3.089 N/A SER 575.A OG LEU 465.A O no hydrogen 3.369 N/A SER 575.A OG ASP 576.A O no hydrogen 2.987 N/A SER 575.A OG ASP 576.A OD1 no hydrogen 3.041 N/A ASP 576.A N ASP 576.A OD1 no hydrogen 2.403 N/A ILE 578.A N ILE 556.A O no hydrogen 3.380 N/A VAL 580.A N TYR 554.A O no hydrogen 3.232 N/A THR 582.A N THR 552.A O no hydrogen 3.326 N/A THR 582.A OG1 LYS 549.A O no hydrogen 3.416 N/A