Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7yrz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A N GLN 294.A OE1 no hydrogen 3.151 N/A LYS 4.A NZ GLU 285.A O no hydrogen 2.863 N/A LYS 4.A NZ GLU 290.A OE1 no hydrogen 3.284 N/A LYS 4.A NZ GLU 290.A OE2 no hydrogen 2.812 N/A GLN 7.A N ASN 111.A OD1 no hydrogen 2.836 N/A GLN 7.A NE2 LEU 150.A O no hydrogen 3.048 N/A SER 9.A OG GLU 13.A OE1 no hydrogen 2.603 N/A GLU 13.A N SER 9.A O no hydrogen 2.910 N/A CYS 15.A N VAL 12.A O no hydrogen 2.790 N/A CYS 15.A SG PHE 11.A O no hydrogen 3.763 N/A VAL 16.A N GLU 13.A O no hydrogen 3.307 N/A VAL 17.A N GLY 28.A O no hydrogen 2.915 N/A ARG 18.A N ILE 67.A O no hydrogen 2.886 N/A ARG 18.A NE ASP 117.A O no hydrogen 3.312 N/A VAL 19.A N LEU 26.A O no hydrogen 2.783 N/A CYS 20.A N SER 65.A O no hydrogen 2.789 N/A TYR 21.A N THR 24.A O no hydrogen 2.944 N/A GLY 22.A N ASN 63.A O no hydrogen 3.431 N/A ASN 23.A ND2 SER 44.A O no hydrogen 3.638 N/A THR 24.A N TYR 21.A O no hydrogen 3.079 N/A THR 24.A OG1 ASN 23.A OD1 no hydrogen 3.338 N/A LEU 26.A N VAL 19.A O no hydrogen 2.902 N/A ASN 27.A N CYS 143.A O no hydrogen 2.925 N/A ASN 27.A ND2 CYS 115.A O no hydrogen 2.999 N/A ASN 27.A ND2 GLY 141.A O no hydrogen 3.099 N/A ASN 27.A ND2 CYS 143.A O no hydrogen 3.022 N/A GLY 28.A N VAL 17.A O no hydrogen 2.908 N/A LEU 29.A N TYR 36.A O no hydrogen 2.849 N/A TRP 30.A N CYS 15.A O no hydrogen 2.771 N/A LEU 31.A N ILE 34.A O no hydrogen 2.904 N/A GLY 32.A N THR 96.A OG1 no hydrogen 2.915 N/A ILE 34.A N LEU 31.A O no hydrogen 3.002 N/A VAL 35.A N ILE 87.A O no hydrogen 2.740 N/A TYR 36.A N LEU 29.A O no hydrogen 2.783 N/A CYS 37.A N LEU 85.A O no hydrogen 3.176 N/A CYS 37.A SG PRO 38.A O no hydrogen 3.592 N/A ARG 39.A N VAL 83.A O no hydrogen 3.028 N/A ARG 39.A NE ASP 185.A OD1 no hydrogen 2.710 N/A ARG 39.A NH2 ASP 185.A OD2 no hydrogen 3.100 N/A VAL 41.A N PRO 38.A O no hydrogen 3.348 N/A ILE 42.A N ARG 39.A O no hydrogen 3.116 N/A ALA 43.A N HIS 40.A O no hydrogen 3.097 N/A SER 44.A OG GLU 55.A OE2 no hydrogen 3.173 N/A THR 47.A N ASN 45.A OD1 no hydrogen 3.062 N/A THR 47.A OG1 ASN 45.A OD1 no hydrogen 2.773 N/A ILE 50.A N GLN 186.A OE1 no hydrogen 2.803 N/A TYR 52.A OH ASP 185.A O no hydrogen 2.787 N/A HIS 54.A N ASP 51.A OD1 no hydrogen 3.149 N/A GLU 55.A N ASP 51.A O no hydrogen 2.925 N/A TYR 56.A N TYR 52.A O no hydrogen 2.833 N/A TYR 56.A OH ALA 78.A O no hydrogen 2.635 N/A SER 57.A N ASP 53.A O no hydrogen 2.999 N/A SER 57.A OG HIS 54.A O no hydrogen 2.815 N/A ILE 58.A N HIS 54.A O no hydrogen 3.141 N/A MET 59.A N TYR 56.A O no hydrogen 3.253 N/A ARG 60.A N TYR 21.A OH no hydrogen 2.937 N/A ARG 60.A NH1 SER 57.A O no hydrogen 3.413 N/A ARG 60.A NH1 MET 59.A O no hydrogen 3.042 N/A ASN 63.A N ARG 60.A O no hydrogen 2.963 N/A ASN 63.A ND2 TYR 21.A OH no hydrogen 3.491 N/A PHE 64.A N LEU 61.A O no hydrogen 3.145 N/A SER 65.A N CYS 20.A O no hydrogen 2.853 N/A ILE 67.A N ARG 18.A O no hydrogen 2.957 N/A SER 68.A N ALA 71.A O no hydrogen 2.806 N/A ALA 71.A N SER 68.A O no hydrogen 2.891 N/A LEU 73.A N ILE 66.A O no hydrogen 2.788 N/A VAL 76.A N LYS 88.A O no hydrogen 2.825 N/A GLY 77.A N LYS 88.A O no hydrogen 3.393 N/A THR 79.A N LYS 86.A O no hydrogen 3.015 N/A THR 79.A OG1 HIS 81.A NE2 no hydrogen 2.628 N/A HIS 81.A N THR 84.A O no hydrogen 2.862 N/A HIS 81.A NE2 THR 79.A OG1 no hydrogen 2.628 N/A VAL 83.A N GLY 177.A O no hydrogen 2.901 N/A THR 84.A N HIS 81.A O no hydrogen 2.906 N/A THR 84.A OG1 HIS 81.A O no hydrogen 2.854 N/A LEU 85.A N CYS 37.A O no hydrogen 2.827 N/A LYS 86.A N THR 79.A O no hydrogen 2.859 N/A ILE 87.A N VAL 35.A O no hydrogen 2.794 N/A LYS 88.A N GLY 77.A O no hydrogen 2.735 N/A VAL 89.A N ASP 33.A O no hydrogen 2.890 N/A SER 90.A N GLY 74.A O no hydrogen 2.779 N/A SER 90.A OG GLY 74.A O no hydrogen 3.537 N/A ASN 93.A N GLY 32.A O no hydrogen 2.791 N/A ASN 93.A ND2 LYS 14.A O no hydrogen 3.522 N/A ASN 93.A ND2 TRP 30.A O no hydrogen 2.866 N/A HIS 95.A N ASN 93.A OD1 no hydrogen 2.928 N/A THR 96.A N ASN 93.A O no hydrogen 2.998 N/A THR 96.A OG1 ASN 93.A O no hydrogen 2.645 N/A HIS 99.A ND1 PRO 97.A O no hydrogen 2.858 N/A SER 100.A N VAL 155.A O no hydrogen 2.956 N/A SER 100.A OG GLU 154.A OE2 no hydrogen 2.743 N/A ARG 102.A N PHE 157.A O no hydrogen 3.181 N/A ARG 102.A NE GLU 156.A OE1 no hydrogen 3.347 N/A ARG 102.A NE GLU 156.A OE2 no hydrogen 3.337 N/A ARG 102.A NH2 GLU 156.A OE1 no hydrogen 3.014 N/A LEU 104.A N TYR 180.A OH no hydrogen 2.860 N/A LYS 105.A N GLU 108.A OE1 no hydrogen 2.868 N/A GLY 107.A N MET 128.A O no hydrogen 2.699 N/A GLU 108.A N LYS 105.A O no hydrogen 3.094 N/A PHE 110.A N VAL 126.A O no hydrogen 2.863 N/A ASN 111.A N TYR 148.A O no hydrogen 2.891 N/A ASN 111.A ND2 GLN 7.A OE1 no hydrogen 2.967 N/A ASN 111.A ND2 TYR 148.A O no hydrogen 2.891 N/A ILE 112.A N PHE 124.A O no hydrogen 2.845 N/A LEU 113.A N PRO 146.A O no hydrogen 3.016 N/A ALA 114.A N GLY 122.A O no hydrogen 2.807 N/A CYS 115.A N SER 145.A OG no hydrogen 2.856 N/A CYS 115.A SG LEU 113.A O no hydrogen 3.341 N/A TYR 116.A N CYS 119.A O no hydrogen 2.964 N/A GLY 118.A N ASN 27.A OD1 no hydrogen 2.799 N/A CYS 119.A N TYR 116.A O no hydrogen 3.045 N/A CYS 119.A SG ALA 120.A O no hydrogen 3.655 N/A GLN 121.A N ALA 114.A O no hydrogen 2.762 N/A GLY 122.A N ALA 114.A O no hydrogen 3.323 N/A PHE 124.A N ILE 112.A O no hydrogen 3.075 N/A VAL 126.A N PHE 110.A O no hydrogen 2.884 N/A ASN 127.A ND2 GLU 285.A O no hydrogen 2.932 N/A MET 128.A N GLU 108.A O no hydrogen 2.970 N/A ARG 129.A N THR 133.A O no hydrogen 3.220 N/A ARG 129.A NE THR 133.A O no hydrogen 3.350 N/A ARG 129.A NE THR 133.A OG1 no hydrogen 3.320 N/A ARG 129.A NH2 THR 133.A OG1 no hydrogen 2.768 N/A ASN 131.A ND2 SER 193.A O no hydrogen 3.022 N/A TRP 132.A N ARG 129.A O no hydrogen 2.925 N/A THR 133.A N ASN 131.A OD1 no hydrogen 3.199 N/A THR 133.A OG1 ASN 131.A OD1 no hydrogen 2.787 N/A ILE 134.A N HIS 170.A O no hydrogen 2.934 N/A GLY 136.A N HIS 170.A ND1 no hydrogen 3.137 N/A ILE 139.A N TYR 116.A OH no hydrogen 3.061 N/A ALA 142.A N ILE 139.A O no hydrogen 3.256 N/A CYS 143.A SG HIS 40.A NE2 no hydrogen 3.621 N/A CYS 143.A SG GLN 162.A O no hydrogen 3.058 N/A GLY 144.A N HIS 161.A O no hydrogen 2.904 N/A SER 145.A N ALA 142.A O no hydrogen 3.058 N/A SER 145.A OG ALA 142.A O no hydrogen 2.705 N/A GLY 147.A N TYR 159.A O no hydrogen 2.660 N/A TYR 148.A N ASN 111.A O no hydrogen 2.817 N/A TYR 148.A OH GLN 7.A O no hydrogen 2.725 N/A ASN 149.A N GLU 156.A O no hydrogen 2.848 N/A ASN 149.A ND2 GLY 109.A O no hydrogen 2.767 N/A LEU 150.A N GLN 7.A OE1 no hydrogen 2.713 N/A LYS 151.A N GLU 154.A O no hydrogen 2.968 N/A GLU 154.A N LYS 151.A O no hydrogen 2.822 N/A VAL 155.A N ARG 98.A O no hydrogen 2.754 N/A GLU 156.A N ASN 149.A O no hydrogen 2.751 N/A PHE 157.A N SER 100.A O no hydrogen 2.953 N/A VAL 158.A N GLY 147.A O no hydrogen 2.906 N/A TYR 159.A N GLY 147.A O no hydrogen 3.371 N/A TYR 159.A OH HIS 161.A ND1 no hydrogen 2.820 N/A MET 160.A N SER 173.A O no hydrogen 2.839 N/A HIS 161.A N SER 145.A O no hydrogen 2.932 N/A HIS 161.A ND1 TYR 159.A OH no hydrogen 2.820 N/A GLN 162.A N VAL 171.A O no hydrogen 3.086 N/A GLN 162.A NE2 VAL 83.A O no hydrogen 3.087 N/A GLN 162.A NE2 SER 173.A OG no hydrogen 3.120 N/A ILE 163.A N VAL 171.A O no hydrogen 2.992 N/A LEU 165.A N SER 169.A O no hydrogen 2.732 N/A SER 167.A OG GLU 192.A OE1 no hydrogen 2.878 N/A SER 167.A OG GLU 192.A OE2 no hydrogen 2.899 N/A GLY 168.A N LEU 165.A O no hydrogen 2.845 N/A SER 169.A N SER 167.A OG no hydrogen 3.268 N/A SER 169.A OG GLU 192.A OE2 no hydrogen 2.736 N/A HIS 170.A N ILE 134.A O no hydrogen 3.012 N/A HIS 170.A NE2 GLU 164.A OE2 no hydrogen 2.834 N/A VAL 171.A N ILE 163.A O no hydrogen 2.960 N/A SER 173.A N MET 160.A O no hydrogen 2.970 N/A SER 173.A OG SER 174.A O no hydrogen 3.095 N/A SER 174.A N VAL 178.A O no hydrogen 2.902 N/A ASP 176.A N SER 174.A OG no hydrogen 3.233 N/A GLY 177.A N SER 174.A O no hydrogen 3.014 N/A TYR 180.A N GLY 172.A O no hydrogen 2.929 N/A TYR 180.A OH VAL 158.A O no hydrogen 2.555 N/A GLY 182.A N MET 179.A O no hydrogen 3.231 N/A GLU 184.A N GLN 190.A OE1 no hydrogen 2.867 N/A GLN 186.A NE2 ILE 50.A O no hydrogen 2.860 N/A ASN 188.A N GLN 186.A O no hydrogen 2.942 N/A ASN 188.A ND2 LEU 189.A O no hydrogen 3.398 N/A GLN 190.A NE2 GLU 184.A O no hydrogen 3.044 N/A GLN 190.A NE2 ASN 188.A O no hydrogen 3.579 N/A GLU 192.A N GLU 192.A OE1 no hydrogen 3.083 N/A GLN 196.A N THR 130.A OG1 no hydrogen 3.095 N/A GLN 196.A NE2 PHE 237.A O no hydrogen 3.336 N/A MET 197.A N GLY 236.A O no hydrogen 2.898 N/A LEU 198.A N ASP 284.A OD1 no hydrogen 2.985 N/A THR 199.A N THR 238.A OG1 no hydrogen 2.781 N/A THR 199.A OG1 TYR 228.A OH no hydrogen 2.678 N/A THR 199.A OG1 THR 238.A O no hydrogen 2.451 N/A ASN 201.A N LEU 198.A O no hydrogen 3.049 N/A ASN 201.A ND2 ASP 284.A O no hydrogen 2.893 N/A VAL 202.A N LEU 198.A O no hydrogen 3.039 N/A VAL 203.A N THR 199.A O no hydrogen 2.926 N/A ALA 204.A N VAL 200.A O no hydrogen 3.113 N/A PHE 205.A N ASN 201.A O no hydrogen 2.892 N/A LEU 206.A N VAL 202.A O no hydrogen 2.932 N/A TYR 207.A N VAL 203.A O no hydrogen 2.989 N/A TYR 207.A OH VAL 255.A O no hydrogen 2.652 N/A ALA 208.A N ALA 204.A O no hydrogen 3.001 N/A ALA 209.A N PHE 205.A O no hydrogen 2.969 N/A ILE 210.A N LEU 206.A O no hydrogen 3.032 N/A LEU 211.A N TYR 207.A O no hydrogen 2.967 N/A ASN 212.A N ALA 208.A O no hydrogen 3.074 N/A ASN 212.A N ALA 209.A O no hydrogen 3.094 N/A GLY 213.A N ILE 210.A O no hydrogen 3.004 N/A CYS 214.A N ALA 209.A O no hydrogen 2.906 N/A CYS 214.A SG GLN 275.A O no hydrogen 3.753 N/A THR 215.A OG1 THR 215.A O no hydrogen 2.407 N/A TRP 216.A NE1 GLN 275.A O no hydrogen 3.264 N/A TRP 217.A NE1 CYS 214.A O no hydrogen 2.973 N/A LEU 218.A N THR 215.A O no hydrogen 3.056 N/A LEU 223.A N GLU 258.A O no hydrogen 3.050 N/A TYR 228.A N PHE 224.A O no hydrogen 2.809 N/A TYR 228.A OH THR 199.A OG1 no hydrogen 2.678 N/A ASN 229.A N VAL 225.A O no hydrogen 2.785 N/A ASN 229.A ND2 MET 240.A O no hydrogen 3.401 N/A GLU 230.A N GLU 226.A O no hydrogen 3.209 N/A TRP 231.A N HIS 227.A O no hydrogen 3.219 N/A ALA 232.A N TYR 228.A O no hydrogen 2.688 N/A GLN 233.A N ASN 229.A O no hydrogen 3.130 N/A ASN 235.A N ALA 232.A O no hydrogen 3.079 N/A ASN 235.A ND2 TRP 231.A O no hydrogen 2.861 N/A PHE 237.A N ALA 232.A O no hydrogen 3.193 N/A THR 238.A N MET 197.A O no hydrogen 2.875 N/A THR 238.A OG1 MET 197.A O no hydrogen 3.342 N/A MET 240.A N ASN 229.A OD1 no hydrogen 2.719 N/A ALA 245.A N GLY 242.A O no hydrogen 2.970 N/A PHE 246.A N GLU 243.A O no hydrogen 3.070 N/A SER 247.A N ASP 244.A O no hydrogen 3.114 N/A SER 247.A OG ASP 244.A O no hydrogen 2.832 N/A ALA 250.A N PHE 246.A O no hydrogen 2.801 N/A ALA 251.A N SER 247.A O no hydrogen 2.875 N/A LYS 252.A N ILE 248.A O no hydrogen 3.245 N/A THR 253.A N LEU 249.A O no hydrogen 3.189 N/A THR 253.A OG1 LEU 249.A O no hydrogen 2.766 N/A THR 253.A OG1 ALA 250.A O no hydrogen 3.368 N/A GLY 254.A N ALA 250.A O no hydrogen 2.699 N/A VAL 255.A N THR 253.A OG1 no hydrogen 3.307 N/A ARG 259.A N CYS 256.A O no hydrogen 3.175 N/A ARG 259.A NE LYS 219.A O no hydrogen 2.996 N/A ARG 259.A NH2 LYS 219.A O no hydrogen 3.337 N/A LEU 261.A N VAL 257.A O no hydrogen 2.853 N/A HIS 262.A N GLU 258.A O no hydrogen 3.153 N/A ALA 263.A N ARG 259.A O no hydrogen 3.149 N/A ILE 264.A N LEU 260.A O no hydrogen 2.903 N/A GLN 265.A N LEU 261.A O no hydrogen 3.263 N/A VAL 266.A N HIS 262.A O no hydrogen 3.315 N/A LEU 267.A N ALA 263.A O no hydrogen 2.799 N/A ASN 268.A N ILE 264.A O no hydrogen 2.864 N/A ASN 269.A N VAL 266.A O no hydrogen 3.286 N/A GLY 270.A N LEU 267.A O no hydrogen 2.958 N/A LYS 274.A N PHE 271.A O no hydrogen 3.039 N/A ILE 276.A N TYR 279.A O no hydrogen 3.117 N/A TYR 279.A N ILE 276.A O no hydrogen 3.104 N/A GLU 285.A N ASN 283.A OD1 no hydrogen 2.753 N/A SER 287.A N GLU 290.A OE1 no hydrogen 2.990 N/A SER 287.A OG GLU 290.A OE1 no hydrogen 3.398 N/A GLU 290.A N SER 287.A OG no hydrogen 3.255 N/A VAL 291.A N SER 287.A O no hydrogen 3.103 N/A VAL 292.A N ILE 288.A O no hydrogen 2.916 N/A LYS 293.A N ASN 289.A O no hydrogen 2.791 N/A GLN 294.A N GLU 290.A O no hydrogen 2.875 N/A GLN 294.A NE2 ARG 3.A O no hydrogen 2.660 N/A MET 295.A N VAL 291.A O no hydrogen 2.870 N/A PHE 296.A N VAL 292.A O no hydrogen 2.891 N/A GLY 297.A N LYS 293.A O no hydrogen 2.858 N/A