Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7z3h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 5.A OG TYR 187.A OH no hydrogen 3.410 N/A GLY 11.A N TRP 133.A O no hydrogen 2.931 N/A ILE 12.A N GLN 181.A O no hydrogen 3.107 N/A SER 13.A N HIS 131.A O no hydrogen 2.862 N/A SER 13.A OG LEU 183.A O no hydrogen 2.824 N/A SER 13.A OG PRO 184.A O no hydrogen 3.353 N/A LEU 15.A N VAL 129.A O no hydrogen 2.785 N/A LEU 16.A N HIS 14.A O no hydrogen 2.996 N/A SER 17.A N GLN 185.A OE1 no hydrogen 3.008 N/A SER 17.A OG GLN 185.A OE1 no hydrogen 2.688 N/A ARG 18.A N LEU 15.A O no hydrogen 3.102 N/A ARG 18.A NE GLU 95.A OE2 no hydrogen 2.913 N/A ARG 18.A NH1 ASP 97.A OD1 no hydrogen 2.958 N/A ARG 18.A NH2 ASP 69.A O no hydrogen 2.989 N/A ARG 18.A NH2 GLU 95.A OE2 no hydrogen 3.183 N/A GLN 19.A N VAL 96.A O no hydrogen 2.819 N/A GLN 19.A NE2 VAL 122.A O no hydrogen 2.946 N/A VAL 21.A N ILE 94.A O no hydrogen 2.708 N/A VAL 22.A N LYS 120.A O no hydrogen 3.001 N/A VAL 23.A N PHE 92.A O no hydrogen 2.668 N/A TYR 24.A N LYS 118.A O no hydrogen 2.917 N/A ASP 27.A N LYS 116.A O no hydrogen 3.095 N/A ALA 28.A N GLY 25.A O no hydrogen 3.285 N/A TYR 31.A N ASP 27.A O no hydrogen 2.830 N/A TYR 31.A OH ILE 108.A O no hydrogen 2.817 N/A LEU 32.A N ALA 28.A O no hydrogen 2.883 N/A GLN 33.A N ALA 29.A O no hydrogen 2.982 N/A GLN 33.A NE2 ASN 39.A OD1 no hydrogen 2.751 N/A GLY 34.A N LYS 30.A O no hydrogen 3.448 N/A MET 35.A N LEU 32.A O no hydrogen 2.880 N/A VAL 36.A N LEU 32.A O no hydrogen 2.979 N/A THR 37.A N ALA 58.A O no hydrogen 2.837 N/A THR 37.A OG1 ALA 58.A O no hydrogen 3.346 N/A THR 37.A OG1 GLY 221.A O no hydrogen 2.602 N/A VAL 40.A N GLN 33.A OE1 no hydrogen 2.664 N/A TYR 41.A N ASN 39.A OD1 no hydrogen 3.130 N/A MET 42.A N MET 48.A O no hydrogen 2.879 N/A SER 45.A N MET 42.A O no hydrogen 3.224 N/A ARG 50.A N VAL 40.A O no hydrogen 2.933 N/A ARG 50.A NE ASP 52.A OD1 no hydrogen 2.435 N/A ARG 50.A NH1 ASN 39.A O no hydrogen 2.971 N/A TYR 55.A N ILE 72.A O no hydrogen 2.935 N/A ALA 57.A N VAL 70.A O no hydrogen 2.961 N/A ALA 58.A N THR 37.A OG1 no hydrogen 3.124 N/A LEU 59.A N TYR 68.A O no hydrogen 2.801 N/A THR 61.A N ARG 65.A O no hydrogen 2.830 N/A THR 61.A OG1 ARG 65.A O no hydrogen 3.517 N/A GLY 64.A N THR 61.A O no hydrogen 2.908 N/A ARG 65.A N THR 61.A OG1 no hydrogen 3.101 N/A ARG 65.A NH1 SER 208.A O no hydrogen 2.919 N/A VAL 66.A N ALA 209.A O no hydrogen 2.759 N/A LEU 67.A N LEU 59.A O no hydrogen 2.727 N/A TYR 68.A N LEU 59.A O no hydrogen 3.214 N/A VAL 70.A N ALA 57.A O no hydrogen 2.938 N/A PHE 71.A N GLU 95.A O no hydrogen 3.211 N/A ILE 72.A N TYR 55.A O no hydrogen 2.797 N/A TYR 73.A N LEU 93.A O no hydrogen 2.772 N/A TYR 73.A OH GLU 95.A OE1 no hydrogen 2.582 N/A LEU 75.A N ALA 91.A O no hydrogen 2.820 N/A SER 78.A N THR 76.A O no hydrogen 3.318 N/A ALA 90.A N GLY 25.A O no hydrogen 3.377 N/A PHE 92.A N VAL 23.A O no hydrogen 2.646 N/A LEU 93.A N TYR 73.A O no hydrogen 2.919 N/A ILE 94.A N VAL 21.A O no hydrogen 2.587 N/A GLU 95.A N PHE 71.A O no hydrogen 2.785 N/A VAL 96.A N GLN 19.A O no hydrogen 2.859 N/A LYS 98.A N SER 17.A O no hydrogen 2.651 N/A GLN 100.A N ASP 97.A O no hydrogen 2.817 N/A ALA 101.A N LYS 98.A O no hydrogen 3.370 N/A LEU 104.A N GLN 100.A O no hydrogen 2.738 N/A VAL 105.A N ALA 101.A O no hydrogen 3.019 N/A ASP 106.A N GLY 102.A O no hydrogen 3.022 N/A HIS 107.A N LEU 103.A O no hydrogen 2.937 N/A ILE 108.A N LEU 104.A O no hydrogen 2.896 N/A LYS 109.A N VAL 105.A O no hydrogen 2.847 N/A ARG 110.A N ASP 106.A O no hydrogen 2.940 N/A ARG 112.A N LYS 109.A O no hydrogen 3.472 N/A ARG 112.A NE LYS 109.A O no hydrogen 3.056 N/A ARG 112.A NH1 VAL 117.A O no hydrogen 2.726 N/A ALA 115.A N ARG 112.A O no hydrogen 2.766 N/A LYS 116.A N ASP 27.A OD2 no hydrogen 2.830 N/A LYS 118.A N TYR 24.A O no hydrogen 2.649 N/A LYS 120.A N VAL 22.A O no hydrogen 3.242 N/A VAL 122.A N LEU 20.A O no hydrogen 2.935 N/A GLU 126.A N ASP 123.A O no hydrogen 2.931 N/A VAL 127.A N ASP 123.A O no hydrogen 3.220 N/A ALA 128.A N HIS 162.A O no hydrogen 2.914 N/A TRP 130.A N ILE 160.A O no hydrogen 2.595 N/A HIS 131.A N SER 13.A O no hydrogen 3.013 N/A HIS 131.A NE2 MET 156.A O no hydrogen 2.749 N/A ALA 132.A N SER 158.A O no hydrogen 3.068 N/A TRP 133.A N GLY 11.A O no hydrogen 2.866 N/A TRP 133.A NE1 ALA 8.A O no hydrogen 2.904 N/A ASN 136.A N ASP 134.A OD1 no hydrogen 2.938 N/A GLY 137.A N ASP 134.A O no hydrogen 2.986 N/A VAL 142.A N LEU 145.A O no hydrogen 3.124 N/A ASN 143.A ND2 ASP 144.A OD1 no hydrogen 3.389 N/A LEU 145.A N VAL 142.A O no hydrogen 2.705 N/A LEU 146.A N LEU 161.A O no hydrogen 2.906 N/A VAL 147.A N ALA 140.A O no hydrogen 2.856 N/A THR 148.A N ARG 159.A O no hydrogen 3.063 N/A ASP 150.A N GLY 157.A O no hydrogen 2.742 N/A CYS 151.A SG PRO 149.A O no hydrogen 3.974 N/A ARG 152.A N ASP 150.A OD1 no hydrogen 3.207 N/A ARG 152.A NE ASP 150.A OD1 no hydrogen 2.922 N/A ARG 152.A NE ASP 150.A OD2 no hydrogen 3.179 N/A ARG 152.A NH1 GLU 199.A OE2 no hydrogen 2.730 N/A ARG 152.A NH2 ASP 150.A OD2 no hydrogen 2.591 N/A ARG 152.A NH2 TYR 188.A OH no hydrogen 3.499 N/A ARG 152.A NH2 GLU 199.A OE2 no hydrogen 2.904 N/A THR 153.A OG1 GLN 195.A OE1 no hydrogen 2.769 N/A ALA 155.A N THR 153.A OG1 no hydrogen 3.324 N/A MET 156.A N THR 153.A O no hydrogen 3.509 N/A SER 158.A N ALA 132.A O no hydrogen 2.836 N/A ARG 159.A NE GLU 95.A OE1 no hydrogen 2.732 N/A ARG 159.A NE GLU 95.A OE2 no hydrogen 3.064 N/A ARG 159.A NH1 HIS 131.A ND1 no hydrogen 3.028 N/A ARG 159.A NH1 TYR 188.A OH no hydrogen 2.849 N/A ARG 159.A NH2 GLU 95.A OE2 no hydrogen 2.572 N/A ARG 159.A NH2 GLU 199.A OE1 no hydrogen 3.504 N/A ARG 159.A NH2 GLU 199.A OE2 no hydrogen 2.838 N/A ILE 160.A N TRP 130.A O no hydrogen 2.830 N/A LEU 161.A N LEU 146.A O no hydrogen 2.831 N/A HIS 162.A N ALA 128.A O no hydrogen 2.896 N/A PHE 163.A N ASP 144.A O no hydrogen 2.910 N/A GLY 165.A N HIS 162.A NE2 no hydrogen 3.504 N/A ASN 173.A N ASN 169.A O no hydrogen 3.093 N/A PHE 174.A N ALA 170.A O no hydrogen 2.908 N/A ALA 175.A N ILE 171.A O no hydrogen 2.806 N/A GLU 176.A N GLN 172.A O no hydrogen 2.948 N/A ARG 177.A N ASN 173.A O no hydrogen 2.773 N/A CYS 178.A N PHE 174.A O no hydrogen 2.841 N/A CYS 178.A SG PHE 174.A O no hydrogen 3.373 N/A GLN 179.A N GLU 176.A O no hydrogen 3.335 N/A LEU 180.A N ALA 175.A O no hydrogen 2.731 N/A LEU 183.A N ILE 12.A O no hydrogen 2.810 N/A TYR 187.A N PRO 184.A O no hydrogen 3.031 N/A TYR 187.A OH SER 5.A OG no hydrogen 3.410 N/A TYR 188.A OH GLU 199.A OE1 no hydrogen 2.634 N/A VAL 189.A N GLN 185.A O no hydrogen 3.042 N/A LEU 190.A N GLU 186.A O no hydrogen 2.943 N/A HIS 191.A N TYR 187.A O no hydrogen 3.043 N/A HIS 191.A NE2 MET 156.A O no hydrogen 2.871 N/A ARG 192.A N TYR 188.A O no hydrogen 2.735 N/A ARG 192.A NH1 VAL 197.A O no hydrogen 2.775 N/A ARG 192.A NH1 GLU 203.A OE1 no hydrogen 2.765 N/A ARG 192.A NH1 GLU 203.A OE2 no hydrogen 3.527 N/A ARG 192.A NH2 GLU 203.A OE2 no hydrogen 2.809 N/A ILE 193.A N VAL 189.A O no hydrogen 2.846 N/A THR 194.A N LEU 190.A O no hydrogen 2.990 N/A THR 194.A OG1 LEU 190.A O no hydrogen 3.337 N/A THR 194.A OG1 HIS 191.A O no hydrogen 2.955 N/A GLN 195.A N HIS 191.A O no hydrogen 3.140 N/A GLN 195.A N ARG 192.A O no hydrogen 3.125 N/A GLY 196.A N ILE 193.A O no hydrogen 2.838 N/A VAL 197.A N ARG 192.A O no hydrogen 3.065 N/A GLU 199.A N GLU 203.A OE1 no hydrogen 2.837 N/A GLY 200.A N ASP 69.A OD2 no hydrogen 2.910 N/A GLN 201.A N ASP 97.A OD2 no hydrogen 3.025 N/A GLN 201.A NE2 ASP 69.A OD1 no hydrogen 2.863 N/A GLN 201.A NE2 LEU 204.A O no hydrogen 3.245 N/A LEU 204.A N GLY 200.A O no hydrogen 2.788 N/A LYS 206.A NZ TYR 68.A OH no hydrogen 2.913 N/A LYS 206.A NZ GLN 100.A OE1 no hydrogen 2.769 N/A MET 207.A N VAL 66.A O no hydrogen 2.762 N/A SER 208.A N LEU 205.A O no hydrogen 3.021 N/A ALA 209.A N LEU 205.A O no hydrogen 2.891 N/A HIS 212.A NE2 GLU 239.A OE1 no hydrogen 2.797 N/A SER 214.A N ILE 210.A O no hydrogen 2.829 N/A SER 214.A OG ILE 210.A O no hydrogen 2.825 N/A ASN 215.A N HIS 212.A O no hydrogen 3.069 N/A ASN 215.A ND2 VAL 248.A O no hydrogen 2.808 N/A LEU 216.A N PRO 211.A O no hydrogen 2.981 N/A MET 219.A N ASN 215.A O no hydrogen 2.954 N/A ASP 223.A N THR 37.A O no hydrogen 3.040 N/A ARG 225.A N ASP 223.A OD1 no hydrogen 2.864 N/A LYS 226.A NZ GLN 33.A O no hydrogen 2.803 N/A LYS 226.A NZ GLN 33.A OE1 no hydrogen 3.247 N/A LYS 226.A NZ VAL 36.A O no hydrogen 2.819 N/A LYS 226.A NZ ALA 38.A O no hydrogen 2.581 N/A VAL 230.A N GLY 34.A O no hydrogen 3.128 N/A GLN 232.A N TYR 229.A O no hydrogen 3.014 N/A VAL 235.A N GLY 231.A O no hydrogen 3.460 N/A THR 236.A N GLN 232.A O no hydrogen 2.725 N/A THR 236.A OG1 GLN 232.A O no hydrogen 2.770 N/A ARG 237.A N GLU 233.A O no hydrogen 2.937 N/A THR 238.A N LEU 234.A O no hydrogen 3.198 N/A THR 238.A OG1 LEU 234.A O no hydrogen 3.130 N/A GLU 239.A N VAL 235.A O no hydrogen 3.017 N/A HIS 240.A N THR 236.A O no hydrogen 2.967 N/A ARG 241.A N ARG 237.A O no hydrogen 2.763 N/A GLY 242.A N THR 238.A O no hydrogen 2.860 N/A ARG 245.A NE GLU 322.A OE1 no hydrogen 2.821 N/A ARG 247.A N CYS 309.A O no hydrogen 3.152 N/A ARG 247.A NH1 ASN 215.A OD1 no hydrogen 2.806 N/A ARG 247.A NH1 ASP 217.A OD1 no hydrogen 3.048 N/A ARG 247.A NH1 ASP 217.A OD2 no hydrogen 3.421 N/A ARG 247.A NH2 ASP 217.A OD2 no hydrogen 2.608 N/A VAL 248.A N GLU 213.A O no hydrogen 2.741 N/A LEU 249.A N ALA 307.A O no hydrogen 2.842 N/A CYS 251.A N GLY 305.A O no hydrogen 2.707 N/A CYS 251.A SG LEU 249.A O no hydrogen 3.988 N/A VAL 252.A N LYS 352.A O no hydrogen 2.875 N/A VAL 253.A N ASN 303.A O no hydrogen 2.614 N/A TYR 254.A N ARG 350.A O no hydrogen 2.979 N/A TYR 254.A OH GLU 339.A OE2 no hydrogen 2.945 N/A LEU 260.A N GLY 258.A O no hydrogen 2.445 N/A LEU 263.A N LEU 260.A O no hydrogen 3.064 N/A TYR 264.A N GLY 261.A O no hydrogen 3.347 N/A TYR 264.A OH PRO 4.A O no hydrogen 2.603 N/A THR 265.A N ASN 303.A OD1 no hydrogen 2.882 N/A ILE 269.A N GLY 271.A O no hydrogen 3.180 N/A SER 274.A N GLY 302.A O no hydrogen 2.708 N/A SER 274.A OG GLU 277.A OE2 no hydrogen 2.858 N/A SER 274.A OG VAL 304.A O no hydrogen 3.282 N/A ALA 275.A N SER 273.A OG no hydrogen 3.384 N/A ARG 276.A N SER 273.A O no hydrogen 3.411 N/A GLU 277.A N SER 274.A O no hydrogen 3.464 N/A SER 280.A OG ALA 279.A O no hydrogen 2.974 N/A GLU 281.A N TRP 297.A O no hydrogen 2.659 N/A ASN 283.A ND2 GLU 343.A OE2 no hydrogen 2.907 N/A ILE 284.A N GLY 295.A O no hydrogen 2.780 N/A VAL 285.A N THR 341.A O no hydrogen 2.764 N/A ARG 286.A NH1 LYS 290.A O no hydrogen 3.154 N/A VAL 287.A N GLU 339.A O no hydrogen 3.148 N/A GLY 289.A N ARG 286.A O no hydrogen 3.302 N/A LYS 290.A N SER 288.A OG no hydrogen 3.398 N/A VAL 294.A N ILE 284.A O no hydrogen 2.845 N/A LYS 296.A N VAL 308.A O no hydrogen 2.816 N/A LYS 296.A NZ ASN 283.A OD1 no hydrogen 2.796 N/A TRP 297.A N THR 282.A O no hydrogen 2.685 N/A LEU 298.A N LEU 306.A O no hydrogen 2.917 N/A ARG 299.A N LEU 306.A O no hydrogen 3.409 N/A ILE 301.A N VAL 304.A O no hydrogen 2.992 N/A ASN 303.A ND2 LEU 263.A O no hydrogen 2.780 N/A VAL 304.A N ILE 301.A O no hydrogen 3.179 N/A GLY 305.A N CYS 251.A O no hydrogen 2.916 N/A LEU 306.A N ARG 299.A O no hydrogen 2.731 N/A ALA 307.A N LEU 249.A O no hydrogen 2.990 N/A VAL 308.A N LYS 296.A O no hydrogen 2.856 N/A CYS 309.A N ARG 247.A O no hydrogen 2.917 N/A CYS 309.A SG ALA 307.A O no hydrogen 3.441 N/A ARG 310.A N VAL 294.A O no hydrogen 2.882 N/A ARG 310.A NE ASP 312.A OD1 no hydrogen 3.054 N/A ARG 310.A NH2 ASP 312.A OD2 no hydrogen 2.646 N/A LEU 311.A N ARG 245.A O no hydrogen 2.650 N/A VAL 313.A N ARG 310.A O no hydrogen 3.245 N/A MET 314.A N ARG 310.A O no hydrogen 2.929 N/A THR 315.A N LEU 311.A O no hydrogen 3.205 N/A THR 315.A OG1 LEU 311.A O no hydrogen 2.555 N/A LEU 317.A N THR 315.A OG1 no hydrogen 3.338 N/A ILE 319.A N THR 323.A OG1 no hydrogen 2.821 N/A GLU 322.A N ILE 319.A O no hydrogen 2.974 N/A THR 323.A N ILE 319.A O no hydrogen 3.023 N/A GLY 326.A N VAL 330.A O no hydrogen 2.708 N/A GLY 329.A N GLY 326.A O no hydrogen 3.342 N/A VAL 330.A N ASP 328.A OD1 no hydrogen 3.301 N/A GLU 332.A N PRO 324.A O no hydrogen 3.034 N/A ARG 334.A NE THR 315.A O no hydrogen 3.511 N/A ARG 334.A NH2 LEU 311.A O no hydrogen 2.859 N/A THR 341.A N VAL 285.A O no hydrogen 2.826 N/A THR 341.A OG1 LEU 349.A O no hydrogen 2.870 N/A GLU 343.A N ASN 283.A O no hydrogen 2.987 N/A GLY 347.A N ASP 345.A OD1 no hydrogen 2.818 N/A ARG 350.A N TYR 254.A O no hydrogen 2.781 N/A ARG 350.A NH1 GLY 347.A O no hydrogen 3.070 N/A ARG 350.A NH1 LEU 349.A O no hydrogen 2.662 N/A ILE 351.A N PHE 340.A O no hydrogen 2.882 N/A LYS 352.A N VAL 252.A O no hydrogen 2.982 N/A VAL 354.A N PRO 250.A O no hydrogen 2.881 N/A TRP 358.A NE1 GLN 195.A O no hydrogen 2.837 N/A ARG 360.A N PRO 356.A O no hydrogen 2.959 N/A ARG 361.A N ALA 357.A O no hydrogen 2.992 N/A GLU 362.A N TRP 358.A O no hydrogen 3.076 N/A LEU 363.A N LEU 359.A O no hydrogen 2.857 N/A MET 364.A N ARG 360.A O no hydrogen 3.036 N/A GLU 365.A N ARG 361.A O no hydrogen 3.061 N/A LYS 366.A N GLU 362.A O no hydrogen 2.972 N/A LYS 366.A NZ ASP 217.A OD2 no hydrogen 2.782 N/A LYS 366.A NZ GLU 239.A OE1 no hydrogen 2.783 N/A LYS 366.A NZ GLU 239.A OE2 no hydrogen 3.152 N/A TRP 367.A N LEU 363.A O no hydrogen 2.873 N/A TRP 367.A NE1 THR 323.A O no hydrogen 2.760 N/A GLU 368.A N MET 364.A O no hydrogen 2.984 N/A VAL 369.A N GLU 365.A O no hydrogen 2.976 N/A LYS 370.A N LYS 366.A O no hydrogen 2.933 N/A LYS 370.A NZ GLU 239.A O no hydrogen 2.905 N/A LYS 370.A NZ HIS 240.A O no hydrogen 2.567 N/A ASN 371.A N TRP 367.A O no hydrogen 2.831 N/A GLU 372.A N GLU 368.A O no hydrogen 3.177 N/A