Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7z4v_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 5.A N LEU 2.A O no hydrogen 3.260 N/A HIS 9.A N ALA 6.A O no hydrogen 3.130 N/A SER 10.A N SER 80.A O no hydrogen 2.903 N/A ARG 11.A NH1 ALA 6.A O no hydrogen 2.952 N/A GLU 15.A N ASP 13.A OD1 no hydrogen 3.314 N/A GLU 16.A N ASP 13.A O no hydrogen 3.133 N/A LEU 17.A N PRO 14.A O no hydrogen 3.010 N/A PHE 18.A N PRO 14.A O no hydrogen 2.913 N/A THR 19.A N ILE 34.A O no hydrogen 2.963 N/A THR 19.A OG1 ASN 36.A OD1 no hydrogen 2.452 N/A LEU 21.A N LYS 32.A O no hydrogen 3.139 N/A ARG 23.A NH2 ILE 24.A O no hydrogen 3.032 N/A ILE 24.A N VAL 30.A O no hydrogen 2.807 N/A SER 26.A OG ASP 154.A OD1 no hydrogen 3.413 N/A SER 26.A OG ASP 154.A OD2 no hydrogen 2.805 N/A VAL 30.A N GLY 25.A O no hydrogen 2.876 N/A TYR 31.A N ILE 44.A O no hydrogen 2.817 N/A LYS 32.A N ASP 22.A O no hydrogen 2.853 N/A GLY 33.A N VAL 42.A O no hydrogen 2.807 N/A ILE 34.A N THR 19.A O no hydrogen 3.190 N/A ASP 35.A N GLU 40.A O no hydrogen 2.967 N/A ASN 36.A N LEU 17.A O no hydrogen 2.903 N/A HIS 37.A N ASP 35.A OD1 no hydrogen 3.029 N/A THR 38.A N ASP 35.A OD1 no hydrogen 3.382 N/A THR 38.A OG1 GLU 40.A OE1 no hydrogen 2.866 N/A LYS 39.A N ASP 35.A O no hydrogen 2.900 N/A LYS 39.A NZ ASN 36.A O no hydrogen 3.372 N/A VAL 42.A N GLY 33.A O no hydrogen 2.863 N/A ALA 43.A N MET 91.A O no hydrogen 2.888 N/A ILE 44.A N TYR 31.A O no hydrogen 2.801 N/A LYS 45.A N ILE 89.A O no hydrogen 2.916 N/A LYS 45.A NZ SER 26.A O no hydrogen 2.814 N/A LYS 45.A NZ GLU 62.A OE1 no hydrogen 3.440 N/A LYS 45.A NZ GLU 62.A OE2 no hydrogen 3.512 N/A ILE 46.A N GLU 29.A O no hydrogen 2.852 N/A ILE 47.A N LEU 87.A O no hydrogen 2.882 N/A LEU 49.A N THR 85.A O no hydrogen 2.834 N/A GLU 50.A N ASP 48.A OD1 no hydrogen 3.028 N/A GLU 51.A N ASP 48.A OD1 no hydrogen 3.302 N/A ALA 52.A N ASP 48.A O no hydrogen 2.865 N/A GLU 55.A N ALA 52.A O no hydrogen 3.059 N/A ILE 56.A N GLU 53.A O no hydrogen 3.457 N/A ILE 59.A N GLU 55.A O no hydrogen 2.982 N/A GLN 60.A N ILE 56.A O no hydrogen 2.991 N/A GLN 60.A NE2 GLN 8.A OE1 no hydrogen 2.881 N/A GLN 61.A N GLU 57.A O no hydrogen 3.021 N/A GLN 61.A NE2 ALA 158.A O no hydrogen 2.907 N/A GLU 62.A N ASP 58.A O no hydrogen 3.028 N/A ILE 63.A N ILE 59.A O no hydrogen 3.155 N/A THR 64.A N GLN 60.A O no hydrogen 2.910 N/A THR 64.A OG1 GLN 60.A O no hydrogen 2.941 N/A THR 64.A OG1 GLN 60.A OE1 no hydrogen 3.058 N/A VAL 65.A N GLN 61.A O no hydrogen 2.920 N/A LEU 66.A N GLU 62.A O no hydrogen 2.907 N/A SER 67.A N ILE 63.A O no hydrogen 2.869 N/A SER 67.A OG ILE 63.A O no hydrogen 3.209 N/A SER 67.A OG THR 64.A O no hydrogen 2.736 N/A GLN 68.A N THR 64.A O no hydrogen 3.170 N/A GLN 68.A N VAL 65.A O no hydrogen 3.146 N/A CYS 69.A N LEU 66.A O no hydrogen 3.252 N/A CYS 69.A SG VAL 65.A O no hydrogen 3.323 N/A ASP 70.A N TYR 126.A OH no hydrogen 3.008 N/A TYR 73.A N SER 71.A OG no hydrogen 3.136 N/A ILE 74.A N SER 71.A O no hydrogen 3.327 N/A THR 75.A N LEU 152.A O no hydrogen 3.182 N/A ARG 76.A N GLU 92.A OE1 no hydrogen 3.012 N/A ARG 76.A NH1 ASP 70.A OD1 no hydrogen 2.983 N/A TYR 77.A OH SER 80.A OG no hydrogen 2.446 N/A PHE 78.A N ILE 90.A O no hydrogen 2.907 N/A SER 80.A OG TYR 77.A OH no hydrogen 2.446 N/A TYR 81.A N TRP 88.A O no hydrogen 2.855 N/A LEU 82.A N SER 10.A O no hydrogen 2.888 N/A LYS 83.A N LYS 86.A O no hydrogen 2.960 N/A LYS 83.A NZ ASP 13.A OD1 no hydrogen 2.735 N/A LYS 86.A N LYS 83.A O no hydrogen 2.970 N/A LEU 87.A N ILE 47.A O no hydrogen 2.888 N/A TRP 88.A N TYR 81.A O no hydrogen 2.851 N/A ILE 89.A N LYS 45.A O no hydrogen 2.819 N/A ILE 90.A N GLY 79.A O no hydrogen 2.830 N/A MET 91.A N ALA 43.A O no hydrogen 2.782 N/A GLU 92.A N ARG 76.A O no hydrogen 2.935 N/A GLY 96.A N LEU 144.A O no hydrogen 2.850 N/A GLY 97.A N LEU 94.A O no hydrogen 3.480 N/A SER 98.A N ASP 101.A OD2 no hydrogen 3.025 N/A ALA 99.A N VAL 142.A O no hydrogen 2.899 N/A ASP 101.A N SER 98.A OG no hydrogen 3.057 N/A LEU 102.A N SER 98.A O no hydrogen 3.036 N/A LEU 103.A N LEU 100.A O no hydrogen 3.273 N/A LYS 104.A N ASP 101.A O no hydrogen 3.079 N/A GLY 106.A N LEU 103.A O no hydrogen 3.250 N/A THR 111.A OG1 TYR 268.A O no hydrogen 3.009 N/A TYR 112.A N GLU 109.A O no hydrogen 2.909 N/A TYR 112.A OH GLU 277.A OE1 no hydrogen 2.617 N/A ILE 113.A N GLU 109.A O no hydrogen 3.091 N/A ALA 114.A N GLU 110.A O no hydrogen 2.902 N/A THR 115.A N THR 111.A O no hydrogen 3.161 N/A THR 115.A OG1 THR 111.A O no hydrogen 2.611 N/A ILE 116.A N TYR 112.A O no hydrogen 2.982 N/A LEU 117.A N ILE 113.A O no hydrogen 2.896 N/A ARG 118.A N ALA 114.A O no hydrogen 2.928 N/A ARG 118.A NE GLU 119.A OE2 no hydrogen 3.050 N/A ARG 118.A NH2 GLU 119.A OE2 no hydrogen 3.287 N/A ARG 118.A NH2 LYS 270.A O no hydrogen 2.726 N/A GLU 119.A N THR 115.A O no hydrogen 3.136 N/A ILE 120.A N ILE 116.A O no hydrogen 2.937 N/A LEU 121.A N LEU 117.A O no hydrogen 2.890 N/A LYS 122.A N ARG 118.A O no hydrogen 3.161 N/A LYS 122.A NZ GLU 119.A OE2 no hydrogen 3.212 N/A GLY 123.A N GLU 119.A O no hydrogen 3.184 N/A LEU 124.A N ILE 120.A O no hydrogen 2.884 N/A ASP 125.A N LEU 121.A O no hydrogen 2.821 N/A TYR 126.A N LYS 122.A O no hydrogen 2.942 N/A LEU 127.A N GLY 123.A O no hydrogen 2.900 N/A HIS 128.A N LEU 124.A O no hydrogen 2.785 N/A HIS 128.A NE2 ASP 192.A OD2 no hydrogen 2.950 N/A SER 129.A N ASP 125.A O no hydrogen 2.966 N/A SER 129.A OG ASP 125.A O no hydrogen 3.360 N/A SER 129.A OG TYR 126.A O no hydrogen 2.784 N/A GLU 130.A N TYR 126.A O no hydrogen 3.179 N/A GLU 130.A N LEU 127.A O no hydrogen 3.181 N/A ARG 131.A N HIS 128.A O no hydrogen 3.015 N/A ARG 131.A NE LEU 161.A O no hydrogen 3.246 N/A ARG 131.A NH2 THR 162.A O no hydrogen 3.154 N/A LYS 132.A N LEU 127.A O no hydrogen 2.860 N/A LYS 132.A NZ GLN 68.A OE1 no hydrogen 2.902 N/A ILE 133.A N GLY 159.A O no hydrogen 2.948 N/A HIS 134.A N ASP 192.A OD2 no hydrogen 2.846 N/A HIS 134.A NE2 ALA 153.A O no hydrogen 2.782 N/A ARG 135.A N ASP 192.A OD1 no hydrogen 2.867 N/A ARG 135.A NE VAL 157.A O no hydrogen 2.814 N/A ARG 135.A NH1 TYR 187.A OH no hydrogen 2.769 N/A ARG 135.A NH2 VAL 157.A O no hydrogen 3.171 N/A ARG 135.A NH2 ALA 158.A O no hydrogen 3.547 N/A ASP 136.A N HIS 134.A ND1 no hydrogen 3.069 N/A LYS 138.A NZ THR 173.A OG1 no hydrogen 2.832 N/A ALA 139.A N GLU 202.A OE1 no hydrogen 3.046 N/A ASN 141.A N LYS 138.A O no hydrogen 2.993 N/A VAL 142.A N ALA 139.A O no hydrogen 3.225 N/A LEU 143.A N LYS 151.A O.A no hydrogen 2.910 N/A LEU 143.A N LYS 151.A O.B no hydrogen 2.908 N/A LEU 144.A N GLY 97.A O no hydrogen 2.881 N/A SER 145.A N ASP 149.A O no hydrogen 2.850 N/A SER 145.A OG ASP 149.A OD2 no hydrogen 2.961 N/A GLN 147.A N SER 145.A OG no hydrogen 3.188 N/A GLY 148.A N SER 145.A O no hydrogen 3.159 N/A ASP 149.A N SER 145.A OG no hydrogen 3.159 N/A LYS 151.A N.A LEU 143.A O no hydrogen 2.857 N/A LYS 151.A N.B LEU 143.A O no hydrogen 2.862 N/A LYS 151.A NZ.A GLU 92.A OE2 no hydrogen 3.210 N/A LYS 151.A NZ.B PRO 72.A O no hydrogen 2.794 N/A LYS 151.A NZ.B GLU 92.A OE1 no hydrogen 3.410 N/A LYS 151.A NZ.B GLU 92.A OE2 no hydrogen 2.876 N/A LEU 152.A N TYR 73.A O no hydrogen 2.873 N/A ALA 153.A N ASN 141.A O no hydrogen 2.927 N/A ALA 158.A N PHE 155.A O no hydrogen 3.110 N/A GLY 159.A N ILE 133.A O no hydrogen 2.828 N/A LEU 161.A N ARG 131.A O no hydrogen 2.931 N/A THR 162.A N GLN 165.A O no hydrogen 2.929 N/A THR 162.A OG1 THR 164.A OG1 no hydrogen 3.379 N/A THR 164.A OG1 THR 162.A OG1 no hydrogen 3.379 N/A ARG 168.A N TYR 187.A O no hydrogen 2.931 N/A ARG 168.A NH1 GLN 160.A O no hydrogen 2.871 N/A THR 173.A OG1 ASP 136.A OD1 no hydrogen 2.715 N/A THR 173.A OG1 ASP 136.A OD2 no hydrogen 3.501 N/A TRP 176.A N THR 173.A O no hydrogen 2.957 N/A TRP 176.A NE1 GLU 202.A OE1 no hydrogen 2.977 N/A MET 177.A N PRO 174.A O no hydrogen 3.224 N/A GLU 180.A N GLU 180.A OE1 no hydrogen 2.777 N/A ILE 182.A N ALA 178.A O no hydrogen 3.017 N/A LYS 183.A N PRO 179.A O no hydrogen 3.082 N/A GLN 184.A N VAL 181.A O no hydrogen 2.883 N/A SER 185.A N GLU 180.A O no hydrogen 3.046 N/A TYR 187.A N ARG 168.A O no hydrogen 2.866 N/A LYS 190.A N ASP 188.A OD1 no hydrogen 3.142 N/A LYS 190.A NZ PRO 250.A O no hydrogen 2.801 N/A LYS 190.A NZ ARG 253.A O no hydrogen 2.748 N/A ALA 191.A N ASP 188.A O no hydrogen 3.080 N/A ASP 192.A N PHE 189.A O no hydrogen 2.943 N/A TRP 194.A N LYS 190.A O no hydrogen 3.245 N/A SER 195.A N ALA 191.A O no hydrogen 3.135 N/A SER 195.A OG TRP 176.A O no hydrogen 2.740 N/A SER 195.A OG ALA 191.A O no hydrogen 3.394 N/A LEU 196.A N ASP 192.A O no hydrogen 2.867 N/A GLY 197.A N ILE 193.A O no hydrogen 3.081 N/A ILE 198.A N TRP 194.A O no hydrogen 3.039 N/A THR 199.A N SER 195.A O no hydrogen 2.909 N/A THR 199.A OG1 SER 195.A O no hydrogen 2.741 N/A ALA 200.A N LEU 196.A O no hydrogen 2.800 N/A ILE 201.A N GLY 197.A O no hydrogen 3.224 N/A GLU 202.A N ILE 198.A O no hydrogen 2.924 N/A LEU 203.A N THR 199.A O no hydrogen 2.815 N/A ALA 204.A N ALA 200.A O no hydrogen 3.281 N/A ALA 204.A N ILE 201.A O no hydrogen 3.020 N/A LYS 205.A N ILE 201.A O no hydrogen 2.854 N/A LYS 205.A NZ GLU 231.A O no hydrogen 2.754 N/A LYS 205.A NZ HIS 234.A NE2 no hydrogen 3.261 N/A GLY 206.A N GLU 202.A O no hydrogen 2.739 N/A SER 211.A OG PRO 208.A O no hydrogen 2.641 N/A LEU 213.A N ASN 210.A O no hydrogen 2.961 N/A MET 216.A N HIS 214.A ND1 no hydrogen 3.073 N/A VAL 218.A N HIS 214.A O no hydrogen 3.034 N/A LEU 219.A N PRO 215.A O no hydrogen 3.092 N/A PHE 220.A N MET 216.A O no hydrogen 3.343 N/A LEU 221.A N ARG 217.A O no hydrogen 2.989 N/A ILE 222.A N VAL 218.A O no hydrogen 2.864 N/A LYS 224.A N LEU 221.A O no hydrogen 3.008 N/A ASN 225.A N LEU 221.A O no hydrogen 2.897 N/A HIS 234.A N GLY 232.A O no hydrogen 2.961 N/A SER 235.A N GLU 110.A OE2 no hydrogen 3.059 N/A SER 235.A OG GLU 110.A OE1 no hydrogen 2.660 N/A LYS 236.A NZ GLU 240.A OE2 no hydrogen 2.736 N/A PHE 238.A N SER 235.A O no hydrogen 3.226 N/A LYS 239.A N SER 235.A O no hydrogen 3.066 N/A LYS 239.A NZ GLY 232.A O no hydrogen 2.977 N/A GLU 240.A N LYS 236.A O no hydrogen 2.865 N/A PHE 241.A N PRO 237.A O no hydrogen 2.993 N/A VAL 242.A N PHE 238.A O no hydrogen 3.053 N/A GLU 243.A N LYS 239.A O no hydrogen 2.901 N/A ALA 244.A N GLU 240.A O no hydrogen 2.965 N/A CYS 245.A N PHE 241.A O no hydrogen 3.169 N/A CYS 245.A SG PHE 241.A O no hydrogen 3.592 N/A LEU 246.A N VAL 242.A O no hydrogen 2.905 N/A LYS 248.A NZ PRO 223.A O no hydrogen 2.924 N/A LYS 248.A NZ ASN 225.A O no hydrogen 2.931 N/A ASP 249.A N ASN 247.A OD1 no hydrogen 3.034 N/A ARG 251.A N ASP 249.A OD1 no hydrogen 3.088 N/A ARG 251.A NE ASP 249.A OD1 no hydrogen 3.075 N/A ARG 251.A NE ASP 249.A OD2 no hydrogen 3.100 N/A ARG 251.A NH2 ASP 249.A OD2 no hydrogen 2.589 N/A PHE 252.A N ASP 249.A O no hydrogen 3.099 N/A ARG 253.A N PRO 250.A O no hydrogen 3.189 N/A ARG 253.A NE ASN 247.A O no hydrogen 2.830 N/A ARG 253.A NH1 GLU 180.A OE1 no hydrogen 3.351 N/A ARG 253.A NH1 GLU 180.A OE2 no hydrogen 2.560 N/A ARG 253.A NH1 LYS 190.A O no hydrogen 2.869 N/A ARG 253.A NH2 GLU 180.A OE1 no hydrogen 2.717 N/A ARG 253.A NH2 ASN 247.A O no hydrogen 3.340 N/A ARG 253.A NH2 LYS 248.A O no hydrogen 3.347 N/A GLU 258.A N THR 255.A OG1 no hydrogen 3.250 N/A LEU 259.A N THR 255.A O no hydrogen 2.927 N/A LEU 260.A N ALA 256.A O no hydrogen 3.043 N/A LYS 261.A N GLU 258.A O no hydrogen 3.229 N/A HIS 262.A N LEU 259.A O no hydrogen 3.087 N/A PHE 264.A N HIS 262.A ND1 no hydrogen 3.017 N/A THR 266.A N HIS 262.A O no hydrogen 3.027 N/A THR 266.A OG1 HIS 262.A O no hydrogen 3.326 N/A THR 266.A OG1 LYS 263.A O no hydrogen 3.438 N/A ARG 267.A N LYS 263.A O no hydrogen 2.952 N/A ARG 267.A NH1 ARG 267.A O no hydrogen 2.969 N/A TYR 268.A N PHE 264.A O no hydrogen 3.274 N/A THR 269.A N ILE 265.A O no hydrogen 3.069 N/A THR 269.A OG1 ILE 265.A O no hydrogen 2.567 N/A LYS 270.A N THR 115.A OG1 no hydrogen 3.227 N/A PHE 274.A N LYS 271.A O no hydrogen 2.962 N/A LEU 275.A N THR 272.A O no hydrogen 2.908 N/A THR 276.A N SER 273.A O no hydrogen 3.496 N/A THR 276.A OG1 SER 273.A O no hydrogen 3.120 N/A GLU 277.A N PHE 274.A O no hydrogen 3.212 N/A LEU 278.A N LEU 275.A O no hydrogen 2.875 N/A ASP 280.A N THR 276.A O no hydrogen 2.902 N/A ARG 281.A N GLU 277.A O no hydrogen 2.968 N/A ARG 281.A NH1 PRO 107.A O no hydrogen 2.857 N/A ARG 281.A NH2 LEU 102.A O no hydrogen 2.832 N/A ARG 281.A NH2 GLY 106.A O no hydrogen 2.966 N/A TYR 282.A N LEU 278.A O no hydrogen 3.029 N/A LYS 283.A N ILE 279.A O no hydrogen 2.966 N/A ARG 284.A N ASP 280.A O no hydrogen 3.099 N/A TRP 285.A N ARG 281.A O no hydrogen 2.898 N/A LYS 286.A N TYR 282.A O no hydrogen 2.894 N/A SER 287.A N LYS 283.A O no hydrogen 2.909 N/A SER 287.A OG LYS 283.A O no hydrogen 3.513 N/A SER 287.A OG ARG 284.A O no hydrogen 2.904 N/A GLU 288.A N ARG 284.A O no hydrogen 2.907 N/A