Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7z5f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 6.A OG1 THR 6.A O no hydrogen 2.391 N/A SER 8.A OG TYR 9.A O no hydrogen 3.567 N/A ASP 10.A N THR 30.A OG1 no hydrogen 3.266 N/A GLN 12.A N ASP 10.A OD1 no hydrogen 3.340 N/A THR 13.A OG1 ASP 89.A OD2 no hydrogen 2.994 N/A HIS 14.A N THR 26.A O no hydrogen 3.227 N/A HIS 14.A NE2 GLN 12.A OE1 no hydrogen 2.995 N/A TYR 15.A OH ASP 89.A OD1 no hydrogen 2.732 N/A ARG 16.A N GLU 24.A O no hydrogen 3.070 N/A LEU 18.A N TRP 22.A O no hydrogen 2.583 N/A GLY 21.A N GLY 19.A O no hydrogen 2.914 N/A VAL 23.A N ALA 497.A O no hydrogen 2.851 N/A GLU 24.A N ARG 16.A O no hydrogen 2.523 N/A ILE 25.A N MET 495.A O no hydrogen 2.869 N/A THR 26.A N HIS 14.A O no hydrogen 2.895 N/A THR 26.A OG1 HIS 14.A O no hydrogen 3.513 N/A ALA 27.A N LEU 493.A O no hydrogen 2.905 N/A ALA 29.A N GLY 491.A O no hydrogen 2.942 N/A THR 30.A N ASN 11.A OD1 no hydrogen 3.010 N/A THR 30.A OG1 ASP 10.A O no hydrogen 2.498 N/A ARG 31.A N TRP 489.A O no hydrogen 2.915 N/A ARG 31.A NE GLY 161.A O no hydrogen 2.756 N/A ARG 31.A NH1 ASN 11.A OD1 no hydrogen 3.428 N/A ARG 31.A NH1 THR 30.A O no hydrogen 3.296 N/A ARG 31.A NH2 GLY 161.A O no hydrogen 3.008 N/A VAL 33.A N PHE 487.A O no hydrogen 2.851 N/A HIS 34.A N THR 168.A O no hydrogen 2.830 N/A LEU 35.A N GLY 485.A O no hydrogen 2.842 N/A MET 37.A N ASN 36.A OD1 no hydrogen 2.787 N/A TYR 43.A OH GLU 213.A OE1 no hydrogen 2.361 N/A CYS 44.A N TRP 70.A O no hydrogen 3.411 N/A CYS 44.A SG TRP 70.A O no hydrogen 3.890 N/A ILE 46.A N GLN 68.A O no hydrogen 2.896 N/A VAL 48.A N HIS 66.A O no hydrogen 2.886 N/A ASN 50.A ND2 LYS 62.A O no hydrogen 3.306 N/A THR 54.A N ASN 50.A O no hydrogen 3.240 N/A THR 54.A OG1 ASN 50.A O no hydrogen 2.877 N/A THR 54.A OG1 ASN 197.A OD1 no hydrogen 3.269 N/A SER 55.A N THR 51.A O no hydrogen 2.901 N/A VAL 56.A N ASP 53.A O no hydrogen 3.117 N/A ASN 59.A ND2 ASP 53.A O no hydrogen 3.064 N/A LYS 62.A N ASN 59.A O no hydrogen 3.301 N/A ALA 65.A N ASP 63.A OD1 no hydrogen 2.982 N/A HIS 66.A N VAL 48.A O no hydrogen 2.926 N/A GLN 68.A N ILE 46.A O no hydrogen 2.914 N/A ILE 69.A N TYR 175.A O no hydrogen 2.858 N/A TRP 70.A N CYS 44.A O no hydrogen 2.894 N/A THR 71.A N TYR 173.A O no hydrogen 3.194 N/A THR 71.A OG1 TYR 173.A O no hydrogen 2.450 N/A SER 74.A N VAL 461.A O no hydrogen 2.602 N/A LEU 75.A N SER 171.A O no hydrogen 2.441 N/A VAL 76.A N MET 459.A O no hydrogen 3.052 N/A ASN 79.A ND2 TRP 431.A O no hydrogen 3.266 N/A ALA 80.A N ALA 78.A O no hydrogen 2.853 N/A GLY 82.A N PRO 426.A O no hydrogen 3.187 N/A VAL 83.A N ALA 80.A O no hydrogen 3.426 N/A TRP 84.A NE1 ALA 78.A O no hydrogen 3.036 N/A LEU 85.A N TRP 81.A O no hydrogen 3.466 N/A GLN 86.A NE2 ASP 89.A OD2 no hydrogen 3.360 N/A TRP 90.A N GLN 86.A O no hydrogen 3.138 N/A GLN 91.A N PRO 87.A O no hydrogen 2.970 N/A GLN 91.A NE2 VAL 511.A O no hydrogen 2.428 N/A TYR 92.A N SER 88.A O no hydrogen 2.927 N/A ILE 93.A N ASP 89.A O no hydrogen 2.934 N/A CYS 94.A N TRP 90.A O no hydrogen 2.905 N/A CYS 94.A SG TRP 90.A O no hydrogen 3.208 N/A CYS 94.A SG ILE 540.A O no hydrogen 4.030 N/A CYS 94.A SG THR 541.A O no hydrogen 3.251 N/A ASN 95.A N GLN 91.A O no hydrogen 2.952 N/A ASN 95.A ND2 GLN 91.A O no hydrogen 2.379 N/A THR 96.A N TYR 92.A O no hydrogen 2.903 N/A THR 96.A OG1 TYR 92.A O no hydrogen 2.912 N/A MET 97.A N ILE 93.A O no hydrogen 2.880 N/A SER 98.A N LYS 498.A O no hydrogen 2.827 N/A LEU 100.A N VAL 239.A O no hydrogen 2.902 N/A ASN 101.A N ARG 496.A O no hydrogen 2.973 N/A VAL 103.A N THR 494.A O no hydrogen 2.854 N/A SER 104.A N THR 494.A O no hydrogen 3.421 N/A SER 104.A OG THR 494.A OG1 no hydrogen 2.899 N/A LEU 105.A N TYR 232.A O no hydrogen 3.000 N/A ASP 106.A N LYS 492.A O no hydrogen 2.917 N/A GLN 107.A N THR 229.A O no hydrogen 3.081 N/A ILE 109.A N PHE 227.A O no hydrogen 2.839 N/A PHE 110.A N PHE 488.A O no hydrogen 2.898 N/A ASN 111.A ND2 SER 5.A OG no hydrogen 2.642 N/A VAL 113.A N THR 486.A O no hydrogen 2.900 N/A LYS 115.A N TYR 484.A O no hydrogen 2.868 N/A VAL 117.A N VAL 482.A O no hydrogen 3.120 N/A THR 118.A N ILE 129.A O no hydrogen 2.890 N/A THR 118.A OG1 ASN 131.A OD1 no hydrogen 3.475 N/A GLN 120.A N ILE 127.A O no hydrogen 2.944 N/A ILE 127.A N GLN 120.A O no hydrogen 2.841 N/A ILE 129.A N THR 118.A O no hydrogen 2.875 N/A ASN 131.A N THR 116.A O no hydrogen 2.882 N/A ASP 133.A N LEU 114.A O no hydrogen 3.062 N/A THR 135.A OG1 ASP 133.A OD2 no hydrogen 3.370 N/A MET 138.A N LEU 221.A O no hydrogen 2.903 N/A MET 139.A N ARG 462.A O no hydrogen 2.839 N/A VAL 140.A N THR 219.A O no hydrogen 2.922 N/A ALA 141.A N LEU 460.A O no hydrogen 2.894 N/A ASP 143.A N GLN 458.A O no hydrogen 2.932 N/A ASN 146.A N ASP 143.A O no hydrogen 3.020 N/A ASN 146.A ND2 ALA 455.A O no hydrogen 3.143 N/A ILE 147.A N ASP 143.A OD1 no hydrogen 3.186 N/A LEU 148.A N ASP 143.A OD2 no hydrogen 3.031 N/A THR 151.A OG1 THR 151.A O no hydrogen 2.369 N/A ALA 153.A N ASP 77.A OD1 no hydrogen 2.507 N/A ASN 155.A N PRO 152.A O no hydrogen 3.367 N/A GLU 158.A N ALA 153.A O no hydrogen 2.632 N/A THR 159.A OG1 ASP 77.A O no hydrogen 2.537 N/A LEU 160.A N ASP 77.A O no hydrogen 3.286 N/A LEU 160.A N THR 159.A OG1 no hydrogen 2.456 N/A PHE 162.A N GLN 343.A O no hydrogen 3.503 N/A LYS 166.A N TYR 163.A O no hydrogen 3.426 N/A THR 168.A N LEU 32.A O no hydrogen 2.991 N/A THR 168.A OG1 ILE 169.A O no hydrogen 3.407 N/A SER 171.A N LEU 75.A O no hydrogen 3.216 N/A TYR 173.A N TRP 73.A O no hydrogen 2.849 N/A TYR 173.A OH PRO 149.A O no hydrogen 2.685 N/A ARG 174.A NH1 GLU 158.A OE1 no hydrogen 3.232 N/A ARG 174.A NH1 PRO 172.A O no hydrogen 2.784 N/A ARG 174.A NH2 GLU 158.A OE1 no hydrogen 3.319 N/A TYR 175.A N ILE 69.A O no hydrogen 2.981 N/A TYR 175.A OH PHE 210.A O no hydrogen 2.601 N/A PHE 177.A N GLU 67.A O no hydrogen 2.903 N/A ARG 181.A NE ASP 63.A OD1 no hydrogen 3.471 N/A ARG 181.A NH1 ASN 197.A OD1 no hydrogen 3.300 N/A ARG 181.A NH2 ASN 197.A OD1 no hydrogen 2.530 N/A ASP 182.A N VAL 198.A O no hydrogen 3.331 N/A SER 184.A N HIS 196.A O no hydrogen 3.033 N/A THR 186.A OG1 TYR 187.A O no hydrogen 3.439 N/A THR 186.A OG1 GLN 190.A OE1 no hydrogen 2.468 N/A GLU 195.A N SER 184.A OG no hydrogen 3.297 N/A HIS 196.A ND1 ASP 182.A OD2 no hydrogen 3.025 N/A ASN 197.A ND2 THR 54.A O no hydrogen 3.308 N/A ASN 197.A ND2 THR 54.A OG1 no hydrogen 3.275 N/A GLY 200.A N ASP 180.A O no hydrogen 2.692 N/A LYS 203.A NZ ASP 180.A OD2 no hydrogen 3.282 N/A SER 207.A OG LYS 203.A O no hydrogen 2.331 N/A PHE 210.A N TYR 175.A OH no hydrogen 2.567 N/A ILE 212.A N TYR 43.A OH no hydrogen 2.968 N/A ASN 214.A N THR 211.A OG1 no hydrogen 3.144 N/A ASN 214.A ND2 THR 211.A OG1 no hydrogen 2.487 N/A THR 215.A OG1 THR 211.A O no hydrogen 2.381 N/A THR 215.A OG1 GLN 216.A OE1 no hydrogen 3.481 N/A GLN 216.A NE2 VAL 142.A O no hydrogen 3.573 N/A GLN 216.A NE2 ASP 143.A OD1 no hydrogen 3.115 N/A THR 219.A N VAL 140.A O no hydrogen 2.862 N/A LEU 221.A N MET 138.A O no hydrogen 2.856 N/A ARG 222.A NE THR 135.A O no hydrogen 2.911 N/A ARG 222.A NH2 THR 135.A O no hydrogen 3.261 N/A ASP 225.A N ARG 222.A O no hydrogen 3.290 N/A PHE 227.A N ILE 109.A O no hydrogen 2.894 N/A THR 229.A N GLN 107.A O no hydrogen 2.928 N/A THR 231.A OG1 ASP 106.A OD2 no hydrogen 2.711 N/A TYR 232.A N LEU 105.A O no hydrogen 3.163 N/A TYR 232.A OH ASN 454.A O no hydrogen 2.237 N/A PHE 234.A N VAL 103.A O no hydrogen 2.870 N/A THR 236.A OG1 ASN 101.A OD1 no hydrogen 3.233 N/A VAL 239.A N LEU 100.A O no hydrogen 2.932 N/A LEU 241.A N SER 98.A O no hydrogen 2.961 N/A HIS 243.A N VAL 544.A O no hydrogen 3.019 N/A HIS 243.A ND1 THR 244.A O no hydrogen 3.344 N/A GLN 246.A NE2 TYR 549.A OXT no hydrogen 3.465 N/A THR 247.A N GLN 250.A OE1 no hydrogen 3.198 N/A THR 247.A OG1 GLN 250.A OE1 no hydrogen 3.187 N/A ARG 249.A N THR 247.A OG1 no hydrogen 3.248 N/A GLN 250.A N THR 247.A O no hydrogen 3.416 N/A THR 259.A N THR 269.A O no hydrogen 3.056 N/A THR 259.A OG1 THR 269.A OG1 no hydrogen 2.877 N/A THR 269.A N THR 259.A OG1 no hydrogen 3.341 N/A THR 269.A OG1 THR 259.A OG1 no hydrogen 2.877 N/A SER 275.A N ALA 272.A O no hydrogen 3.341 N/A ARG 276.A NE THR 271.A O no hydrogen 2.966 N/A ARG 276.A NH2 THR 271.A O no hydrogen 2.733 N/A THR 279.A OG1 THR 280.A O no hydrogen 3.480 N/A THR 279.A OG1 THR 293.A OG1 no hydrogen 3.420 N/A VAL 287.A N GLN 273.A O no hydrogen 3.318 N/A ALA 290.A N SER 288.A OG no hydrogen 3.328 N/A ARG 292.A NE GLU 289.A OE1 no hydrogen 3.049 N/A ARG 292.A NH1 GLN 253.A O no hydrogen 3.231 N/A ARG 292.A NH2 GLN 253.A O no hydrogen 2.795 N/A THR 293.A N THR 279.A O no hydrogen 3.288 N/A THR 293.A OG1 THR 279.A OG1 no hydrogen 3.420 N/A ARG 294.A NE ASN 248.A O no hydrogen 2.587 N/A GLN 297.A N LEU 415.A O no hydrogen 2.763 N/A CYS 301.A N SER 411.A OG no hydrogen 2.818 N/A GLN 302.A NE2 VAL 320.A O no hydrogen 3.106 N/A GLU 308.A N PHE 315.A O no hydrogen 2.904 N/A SER 310.A OG SER 310.A O no hydrogen 2.425 N/A PHE 315.A N GLU 308.A O no hydrogen 2.882 N/A ALA 317.A N ASP 306.A O no hydrogen 3.017 N/A VAL 320.A N GLN 302.A OE1 no hydrogen 3.373 N/A ALA 322.A N ASN 333.A O no hydrogen 3.146 N/A THR 325.A OG1 GLY 327.A O no hydrogen 3.043 N/A THR 325.A OG1 ARG 369.A O no hydrogen 3.398 N/A LYS 330.A NZ ASP 361.A OD2 no hydrogen 3.419 N/A ASN 333.A ND2 ARG 369.A O no hydrogen 3.374 N/A SER 335.A N LYS 330.A O no hydrogen 3.241 N/A SER 335.A OG LYS 330.A O no hydrogen 3.198 N/A TYR 338.A N TYR 358.A O no hydrogen 2.869 N/A TYR 340.A N GLU 356.A O no hydrogen 2.880 N/A LYS 342.A NZ TRP 348.A O no hydrogen 3.361 N/A LYS 342.A NZ SER 350.A O no hydrogen 3.278 N/A HIS 344.A N GLY 341.A O no hydrogen 3.090 N/A GLU 346.A N GLY 341.A O no hydrogen 2.865 N/A TRP 348.A NE1 LYS 342.A O no hydrogen 2.992 N/A SER 350.A N ASN 347.A O no hydrogen 3.249 N/A SER 350.A OG ASN 347.A O no hydrogen 3.491 N/A GLU 356.A N TYR 340.A O no hydrogen 2.924 N/A ARG 357.A NH1 SER 339.A OG no hydrogen 3.028 N/A TYR 358.A N TYR 338.A O no hydrogen 2.906 N/A TRP 360.A N VAL 336.A O no hydrogen 2.789 N/A SER 364.A OG SER 364.A O no hydrogen 2.302 N/A PHE 365.A N THR 244.A O no hydrogen 3.047 N/A SER 367.A N SER 364.A O no hydrogen 3.155 N/A ARG 369.A N ASN 333.A OD1 no hydrogen 2.967 N/A ARG 369.A NH1 GLY 368.A O no hydrogen 2.461 N/A THR 371.A OG1 ASP 329.A OD2 no hydrogen 2.635 N/A ILE 376.A N LEU 391.A O no hydrogen 2.937 N/A GLY 389.A N PRO 386.A O no hydrogen 3.380 N/A LEU 391.A N ILE 376.A O no hydrogen 2.818 N/A THR 392.A N ASN 395.A OD1 no hydrogen 3.352 N/A ILE 397.A N ILE 403.A O no hydrogen 3.178 N/A LYS 400.A N ILE 397.A O no hydrogen 3.331 N/A ASP 402.A N ASP 402.A OD1 no hydrogen 2.397 N/A ILE 403.A N LYS 400.A O no hydrogen 3.424 N/A HIS 404.A N ASN 407.A OD1 no hydrogen 2.719 N/A SER 406.A OG ASN 393.A OD1 no hydrogen 3.242 N/A ASN 407.A N HIS 404.A O no hydrogen 3.330 N/A VAL 408.A N PHE 405.A O no hydrogen 3.350 N/A SER 411.A N CYS 301.A O no hydrogen 3.192 N/A TYR 412.A N ASN 410.A OD1 no hydrogen 3.251 N/A GLY 413.A N THR 416.A OG1 no hydrogen 3.257 N/A THR 416.A OG1 GLN 297.A OE1 no hydrogen 3.279 N/A ALA 417.A N GLN 297.A O no hydrogen 2.709 N/A SER 422.A N GLU 362.A OE2 no hydrogen 2.813 N/A SER 422.A OG GLU 362.A OE2 no hydrogen 3.192 N/A TYR 425.A OH LEU 85.A O no hydrogen 2.487 N/A GLN 429.A NE2 TRP 431.A O no hydrogen 2.858 N/A ASP 432.A N PHE 449.A O no hydrogen 3.326 N/A LYS 433.A N ASP 432.A OD1 no hydrogen 2.806 N/A LEU 437.A N LEU 435.A O no hydrogen 2.840 N/A LYS 440.A NZ LEU 435.A O no hydrogen 3.289 N/A LYS 440.A NZ LEU 437.A O no hydrogen 3.265 N/A HIS 444.A ND1 ASP 432.A OD2 no hydrogen 3.325 N/A THR 446.A OG1 ASP 432.A OD2 no hydrogen 2.697 N/A PHE 449.A N ILE 430.A O no hydrogen 3.410 N/A CYS 451.A N ASP 432.A O no hydrogen 3.149 N/A CYS 451.A SG TYR 232.A OH no hydrogen 3.480 N/A CYS 451.A SG ASP 432.A O no hydrogen 3.754 N/A ASN 454.A N ASN 453.A OD1 no hydrogen 2.791 N/A GLN 458.A NE2 PRO 149.A O no hydrogen 2.897 N/A LEU 460.A N ALA 141.A O no hydrogen 2.861 N/A VAL 461.A N SER 74.A O no hydrogen 2.727 N/A ARG 462.A N MET 139.A O no hydrogen 2.948 N/A ARG 462.A NE LEU 463.A O no hydrogen 3.131 N/A ARG 462.A NH2 GLU 41.A OE1 no hydrogen 3.077 N/A GLY 464.A N CYS 137.A O no hydrogen 3.148 N/A THR 468.A OG1 GLN 470.A O no hydrogen 3.009 N/A THR 468.A OG1 SER 479.A OG no hydrogen 2.365 N/A ASN 474.A N ASP 472.A OD1 no hydrogen 3.359 N/A GLY 475.A N ASP 472.A O no hydrogen 3.357 N/A THR 477.A N GLY 475.A O no hydrogen 2.950 N/A SER 479.A OG THR 468.A OG1 no hydrogen 2.365 N/A SER 479.A OG GLN 470.A O no hydrogen 3.288 N/A ARG 480.A NH1 PRO 38.A O no hydrogen 3.408 N/A ARG 480.A NH2 PRO 38.A O no hydrogen 2.410 N/A THR 483.A OG1 LYS 115.A O no hydrogen 3.399 N/A THR 483.A OG1 TYR 484.A O no hydrogen 3.297 N/A TYR 484.A N LYS 115.A O no hydrogen 2.886 N/A GLY 485.A N LEU 35.A O no hydrogen 2.889 N/A THR 486.A N VAL 113.A O no hydrogen 2.868 N/A PHE 487.A N VAL 33.A O no hydrogen 2.952 N/A PHE 488.A N PHE 110.A O no hydrogen 2.801 N/A TRP 489.A N ARG 31.A O no hydrogen 2.906 N/A LYS 490.A N GLU 108.A O no hydrogen 3.076 N/A LYS 490.A NZ SER 8.A O no hydrogen 2.821 N/A GLY 491.A N ALA 29.A O no hydrogen 2.861 N/A LYS 492.A N ASP 106.A O no hydrogen 2.889 N/A LEU 493.A N ALA 27.A O no hydrogen 2.881 N/A THR 494.A N SER 104.A O no hydrogen 2.912 N/A THR 494.A OG1 SER 104.A OG no hydrogen 2.899 N/A MET 495.A N ILE 25.A O no hydrogen 2.841 N/A ARG 496.A N ASN 101.A O no hydrogen 2.834 N/A ALA 497.A N VAL 23.A O no hydrogen 2.911 N/A LEU 499.A N GLY 21.A O no hydrogen 3.051 N/A ARG 500.A N THR 96.A O no hydrogen 2.850 N/A THR 504.A OG1 ASN 506.A O no hydrogen 3.290 N/A THR 504.A OG1 ASN 506.A OD1 no hydrogen 3.338 N/A GLN 510.A NE2 TYR 509.A O no hydrogen 2.962 N/A VAL 511.A N ASN 95.A OD1 no hydrogen 2.957 N/A GLU 514.A N MET 521.A O no hydrogen 2.628 N/A TYR 520.A OH PRO 538.A O no hydrogen 2.455 N/A MET 521.A N SER 519.A OG no hydrogen 3.253 N/A SER 522.A OG SER 519.A O no hydrogen 3.507 N/A VAL 523.A N GLU 514.A O no hydrogen 3.050 N/A THR 524.A OG1 ASN 516.A OD1 no hydrogen 3.218 N/A LYS 525.A NZ TYR 520.A O no hydrogen 2.788 N/A TRP 526.A N VAL 523.A O no hydrogen 2.925 N/A THR 531.A N THR 529.A OG1 no hydrogen 3.381 N/A GLY 532.A N THR 529.A O no hydrogen 3.201 N/A SER 536.A N GLY 345.A O no hydrogen 3.225 N/A THR 541.A OG1 PRO 423.A O no hydrogen 2.350 N/A ARG 542.A NH1 HIS 420.A O no hydrogen 2.950 N/A ARG 542.A NH2 HIS 420.A O no hydrogen 2.848 N/A ARG 546.A N HIS 243.A O no hydrogen 2.669 N/A ARG 546.A NH1 THR 242.A OG1 no hydrogen 3.312 N/A TYR 549.A N GLN 246.A OE1 no hydrogen 2.870 N/A