Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7zhq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N GLU 27.A OE1 no hydrogen 2.825 N/A LEU 4.A N TYR 29.A OH no hydrogen 3.125 N/A ASN 7.A N VAL 16.A O no hydrogen 2.820 N/A TYR 8.A N PRO 5.A O no hydrogen 3.042 N/A VAL 10.A N TRP 14.A O no hydrogen 2.802 N/A ARG 13.A N VAL 10.A O no hydrogen 2.906 N/A ARG 13.A NE ASP 33.A OD1 no hydrogen 2.936 N/A ARG 13.A NE ASP 33.A OD2 no hydrogen 3.351 N/A ARG 13.A NH2 ASP 33.A OD1 no hydrogen 3.480 N/A ARG 13.A NH2 ASP 33.A OD2 no hydrogen 2.845 N/A TRP 14.A N VAL 10.A O no hydrogen 2.983 N/A TRP 14.A NE1 ASP 33.A OD2 no hydrogen 2.880 N/A LYS 15.A N MET 32.A O no hydrogen 2.834 N/A VAL 16.A N TYR 8.A O no hydrogen 2.814 N/A LEU 17.A N GLU 30.A O no hydrogen 2.781 N/A LYS 18.A N GLU 30.A O no hydrogen 3.316 N/A LYS 19.A NZ ASP 2.A OD1 no hydrogen 3.020 N/A ILE 20.A N ILE 28.A O no hydrogen 2.791 N/A GLY 21.A N ILE 28.A O no hydrogen 3.119 N/A GLY 23.A N GLY 26.A O no hydrogen 3.014 N/A GLU 27.A N VAL 44.A O no hydrogen 3.090 N/A ILE 28.A N GLY 21.A O no hydrogen 2.917 N/A TYR 29.A N LEU 42.A O no hydrogen 2.761 N/A TYR 29.A OH GLU 27.A OE1 no hydrogen 2.462 N/A GLU 30.A N LYS 18.A O no hydrogen 2.884 N/A ALA 31.A N VAL 40.A O no hydrogen 2.941 N/A MET 32.A N LYS 15.A O no hydrogen 2.803 N/A ASP 33.A N GLU 38.A O no hydrogen 2.927 N/A LEU 34.A N ARG 13.A O no hydrogen 2.775 N/A LEU 35.A N ASP 33.A OD1 no hydrogen 2.992 N/A THR 36.A N ASP 33.A OD1 no hydrogen 3.123 N/A ARG 37.A N ASP 33.A O no hydrogen 2.839 N/A ARG 37.A NH1 LEU 34.A O no hydrogen 2.945 N/A ASN 39.A ND2 GLU 30.A OE2 no hydrogen 2.897 N/A VAL 40.A N ALA 31.A O no hydrogen 2.746 N/A ALA 41.A N MET 87.A O no hydrogen 2.938 N/A LEU 42.A N TYR 29.A O no hydrogen 2.761 N/A LYS 43.A N VAL 85.A O no hydrogen 2.865 N/A LYS 43.A NZ GLU 57.A OE1 no hydrogen 3.107 N/A LYS 43.A NZ GLU 57.A OE2 no hydrogen 3.111 N/A VAL 44.A N GLU 27.A O no hydrogen 2.839 N/A GLU 45.A N ASN 83.A O no hydrogen 2.910 N/A ALA 47.A N LYS 81.A O no hydrogen 2.977 N/A GLN 48.A N SER 46.A OG no hydrogen 3.312 N/A GLN 48.A NE2 GLU 80.A O no hydrogen 3.263 N/A GLN 49.A N SER 46.A O no hydrogen 3.267 N/A GLN 49.A NE2 PHE 25.A O no hydrogen 2.888 N/A GLN 49.A NE2 LYS 51.A O no hydrogen 2.888 N/A GLN 52.A NE2 SER 46.A O no hydrogen 3.353 N/A GLN 52.A NE2 GLN 49.A O no hydrogen 2.960 N/A VAL 53.A N GLU 45.A OE2 no hydrogen 2.866 N/A LEU 54.A N GLU 45.A OE2 no hydrogen 2.834 N/A MET 56.A N VAL 53.A O no hydrogen 2.947 N/A GLU 57.A N VAL 53.A O no hydrogen 3.174 N/A VAL 58.A N LEU 54.A O no hydrogen 2.864 N/A ALA 59.A N LYS 55.A O no hydrogen 3.114 N/A VAL 60.A N MET 56.A O no hydrogen 2.932 N/A LEU 61.A N GLU 57.A O no hydrogen 2.917 N/A LYS 62.A N VAL 58.A O no hydrogen 2.921 N/A LYS 63.A N ALA 59.A O no hydrogen 3.018 N/A LEU 64.A N VAL 60.A O no hydrogen 3.120 N/A LEU 64.A N LEU 61.A O no hydrogen 3.155 N/A GLN 65.A N LYS 62.A O no hydrogen 3.195 N/A GLN 65.A NE2 LEU 61.A O no hydrogen 2.966 N/A GLN 65.A NE2 CYS 71.A O no hydrogen 3.041 N/A LYS 67.A N LEU 64.A O no hydrogen 2.942 N/A HIS 69.A N ASP 68.A OD1 no hydrogen 2.795 N/A HIS 69.A NE2 GLU 120.A OE1.A no hydrogen 2.751 N/A HIS 69.A NE2 GLU 120.A OE1.B no hydrogen 3.142 N/A CYS 71.A SG GLN 88.A O no hydrogen 3.776 N/A ARG 72.A N GLN 88.A OE1 no hydrogen 3.006 N/A PHE 73.A N GLN 65.A OE1 no hydrogen 2.756 N/A ILE 74.A N VAL 86.A O no hydrogen 2.948 N/A GLY 75.A N VAL 86.A O no hydrogen 3.173 N/A GLY 77.A N TYR 84.A O no hydrogen 3.152 N/A ASN 79.A N PHE 82.A O no hydrogen 3.192 N/A GLU 80.A N GLU 80.A OE1 no hydrogen 2.436 N/A LYS 81.A N ASN 79.A OD1 no hydrogen 3.020 N/A PHE 82.A N ASN 79.A OD1 no hydrogen 3.151 N/A ASN 83.A N GLU 45.A O no hydrogen 2.853 N/A ASN 83.A ND2 GLU 45.A OE1 no hydrogen 3.330 N/A ASN 83.A ND2 GLN 52.A OE1 no hydrogen 2.945 N/A TYR 84.A N GLY 77.A O no hydrogen 2.927 N/A VAL 85.A N LYS 43.A O no hydrogen 2.846 N/A VAL 86.A N GLY 75.A O no hydrogen 2.760 N/A MET 87.A N ALA 41.A O no hydrogen 2.949 N/A GLN 88.A N ARG 72.A O no hydrogen 2.958 N/A GLY 91.A N MET 142.A O no hydrogen 2.830 N/A LEU 94.A N PHE 140.A O no hydrogen 3.033 N/A ASP 96.A N ASN 93.A OD1 no hydrogen 2.852 N/A LEU 97.A N ASN 93.A O no hydrogen 3.076 N/A ARG 98.A N LEU 94.A O no hydrogen 2.914 N/A ARG 98.A NH1 GLY 104.A O no hydrogen 2.773 N/A ARG 99.A N ALA 95.A O no hydrogen 3.025 N/A SER 100.A N ASP 96.A O no hydrogen 3.052 N/A SER 100.A N LEU 97.A O no hydrogen 3.261 N/A SER 100.A OG ASP 96.A O no hydrogen 3.162 N/A GLN 101.A N ARG 98.A O no hydrogen 3.081 N/A GLY 104.A N GLN 101.A O no hydrogen 2.975 N/A PHE 106.A N PHE 212.A O no hydrogen 2.809 N/A THR 107.A N ASP 289.A OD2 no hydrogen 2.752 N/A THR 107.A OG1 ASP 289.A OD1 no hydrogen 2.701 N/A THR 107.A OG1 ASP 289.A OD2 no hydrogen 3.409 N/A SER 109.A OG GLU 286.A OE1 no hydrogen 2.751 N/A THR 110.A N THR 107.A OG1 no hydrogen 3.235 N/A THR 111.A N THR 107.A O no hydrogen 2.941 N/A THR 111.A OG1 THR 107.A O no hydrogen 2.872 N/A LEU 112.A N LEU 108.A O no hydrogen 2.833 N/A ARG 113.A N SER 109.A O no hydrogen 3.156 N/A ARG 113.A NE SER 109.A O no hydrogen 3.070 N/A ARG 113.A NE SER 109.A OG no hydrogen 3.079 N/A ARG 113.A NH2 SER 109.A OG no hydrogen 2.719 N/A ARG 113.A NH2 ALA 287.A O no hydrogen 3.042 N/A LEU 114.A N THR 110.A O no hydrogen 2.946 N/A GLY 115.A N THR 111.A O no hydrogen 2.942 N/A LYS 116.A N LEU 112.A O no hydrogen 3.038 N/A LYS 116.A NZ GLU 284.A OE2 no hydrogen 2.668 N/A GLN 117.A N ARG 113.A O no hydrogen 3.319 N/A GLN 117.A NE2 ARG 150.A O no hydrogen 3.126 N/A ILE 118.A N LEU 114.A O no hydrogen 2.827 N/A LEU 119.A N GLY 115.A O no hydrogen 2.847 N/A GLU 120.A N LYS 116.A O no hydrogen 3.033 N/A SER 121.A N GLN 117.A O no hydrogen 3.087 N/A SER 121.A OG.A ILE 118.A O no hydrogen 2.600 N/A SER 121.A OG.B HIS 69.A O no hydrogen 3.473 N/A ILE 122.A N ILE 118.A O no hydrogen 2.832 N/A GLU 123.A N LEU 119.A O no hydrogen 2.942 N/A ALA 124.A N GLU 120.A O no hydrogen 2.983 N/A ILE 125.A N SER 121.A O no hydrogen 3.100 N/A HIS 126.A N ILE 122.A O no hydrogen 3.062 N/A HIS 126.A ND1 TYR 266.A OH no hydrogen 2.607 N/A HIS 126.A NE2 ASP 201.A OD2 no hydrogen 2.729 N/A SER 127.A N GLU 123.A O no hydrogen 2.778 N/A SER 127.A OG ALA 124.A O no hydrogen 2.585 N/A VAL 128.A N ILE 125.A O no hydrogen 3.085 N/A GLY 129.A N HIS 126.A O no hydrogen 2.924 N/A PHE 130.A N ILE 125.A O no hydrogen 3.253 N/A LEU 131.A N ARG 161.A O no hydrogen 2.847 N/A HIS 132.A N ASP 201.A OD2 no hydrogen 3.065 N/A HIS 132.A NE2 LEU 155.A O no hydrogen 2.985 N/A ARG 133.A N ASP 201.A OD1 no hydrogen 2.870 N/A ARG 133.A NE LEU 159.A O no hydrogen 2.813 N/A ARG 133.A NH1 LEU 159.A O no hydrogen 2.946 N/A ASP 134.A N HIS 132.A ND1 no hydrogen 2.991 N/A LYS 136.A NZ THR 182.A OG1 no hydrogen 2.809 N/A ASN 139.A N LYS 136.A O no hydrogen 3.046 N/A ASN 139.A ND2 ASP 134.A O no hydrogen 2.935 N/A PHE 140.A N PRO 137.A O no hydrogen 3.155 N/A ALA 141.A N TYR 153.A O no hydrogen 2.968 N/A MET 142.A N ARG 92.A O no hydrogen 2.894 N/A GLY 143.A N LYS 151.A O no hydrogen 2.854 N/A ARG 144.A NH2 GLN 90.A O no hydrogen 2.967 N/A LEU 145.A N THR 148.A OG1 no hydrogen 3.080 N/A THR 148.A N LEU 145.A O no hydrogen 2.842 N/A THR 148.A OG1 LEU 145.A O no hydrogen 3.399 N/A ARG 150.A NH1 GLU 286.A O no hydrogen 2.870 N/A ARG 150.A NH1 GLU 291.A OE2 no hydrogen 2.934 N/A ARG 150.A NH2 GLU 284.A O no hydrogen 3.380 N/A ARG 150.A NH2 GLU 286.A O no hydrogen 2.128 N/A LYS 151.A N THR 148.A O no hydrogen 2.907 N/A LYS 151.A NZ SER 147.A O no hydrogen 3.206 N/A CYS 152.A N GLN 117.A OE1 no hydrogen 2.760 N/A TYR 153.A N ALA 141.A O no hydrogen 2.767 N/A MET 154.A N HIS 69.A O no hydrogen 3.047 N/A LEU 155.A N ASN 139.A O no hydrogen 2.824 N/A GLY 158.A N ASP 156.A OD1 no hydrogen 2.937 N/A ALA 160.A N PHE 157.A O no hydrogen 3.045 N/A ARG 161.A N LEU 131.A O no hydrogen 3.130 N/A GLN 162.A NE2 THR 164.A O no hydrogen 3.223 N/A GLN 162.A NE2 THR 164.A OG1 no hydrogen 3.280 N/A GLN 162.A NE2 ASN 165.A O no hydrogen 3.590 N/A TYR 163.A N GLY 129.A O no hydrogen 2.864 N/A TYR 163.A OH HIS 126.A O no hydrogen 2.594 N/A THR 164.A OG1 ASN 165.A O no hydrogen 3.463 N/A ASN 165.A N ASP 169.A O no hydrogen 2.855 N/A ASN 165.A ND2 ASP 169.A OD2 no hydrogen 2.949 N/A THR 167.A N ASN 165.A OD1 no hydrogen 2.987 N/A THR 167.A OG1 ASN 165.A OD1 no hydrogen 3.229 N/A THR 167.A OG1 ASP 169.A OD2 no hydrogen 2.959 N/A GLY 168.A N ASN 165.A O no hydrogen 3.447 N/A ASP 169.A N ASN 165.A OD1 no hydrogen 2.838 N/A ARG 171.A N TYR 163.A O no hydrogen 2.804 N/A ARG 171.A NH1 GLN 162.A O no hydrogen 2.894 N/A ARG 174.A N GLU 195.A OE1 no hydrogen 2.854 N/A ARG 174.A NE GLU 195.A OE1 no hydrogen 2.775 N/A ARG 174.A NH2 GLU 195.A OE2 no hydrogen 2.939 N/A ALA 177.A N ASN 193.A O no hydrogen 2.891 N/A PHE 179.A N ASN 193.A OD1 no hydrogen 2.985 N/A THR 182.A N ASP 134.A OD1 no hydrogen 2.807 N/A THR 182.A OG1 ASP 134.A OD1 no hydrogen 3.057 N/A THR 182.A OG1 ASP 134.A OD2 no hydrogen 2.852 N/A ARG 184.A NH1 GLU 211.A OE2 no hydrogen 2.896 N/A TYR 185.A OH GLU 211.A OE1 no hydrogen 2.509 N/A TYR 185.A OH GLU 211.A OE2 no hydrogen 3.325 N/A ALA 186.A N VAL 183.A O no hydrogen 3.135 N/A SER 187.A OG ASP 200.A OD1 no hydrogen 2.650 N/A ASN 189.A ND2 ASP 200.A OD1 no hydrogen 2.841 N/A ALA 190.A N SER 187.A OG no hydrogen 3.032 N/A HIS 191.A N SER 187.A O no hydrogen 3.016 N/A LYS 192.A N VAL 188.A O no hydrogen 3.072 N/A LYS 192.A N ASN 189.A O no hydrogen 3.111 N/A LYS 192.A NZ GLU 233.A OE2 no hydrogen 3.009 N/A ASN 193.A N ALA 190.A O no hydrogen 2.944 N/A ARG 194.A N ASN 189.A O no hydrogen 3.209 N/A GLY 197.A N ASP 200.A OD2 no hydrogen 2.850 N/A ASP 200.A N GLY 197.A O no hydrogen 3.037 N/A LEU 202.A N ARG 198.A O no hydrogen 3.401 N/A TRP 203.A N HIS 199.A O no hydrogen 2.857 N/A SER 204.A N ASP 200.A O no hydrogen 3.154 N/A SER 204.A OG TYR 185.A O no hydrogen 2.813 N/A SER 204.A OG ASP 200.A O no hydrogen 3.315 N/A LEU 205.A N ASP 201.A O no hydrogen 3.084 N/A PHE 206.A N LEU 202.A O no hydrogen 2.876 N/A TYR 207.A N TRP 203.A O no hydrogen 2.995 N/A TYR 207.A OH HIS 237.A NE2 no hydrogen 2.687 N/A MET 208.A N SER 204.A O no hydrogen 2.898 N/A LEU 209.A N LEU 205.A O no hydrogen 2.998 N/A VAL 210.A N PHE 206.A O no hydrogen 3.218 N/A GLU 211.A N TYR 207.A O no hydrogen 3.073 N/A PHE 212.A N MET 208.A O no hydrogen 2.872 N/A ALA 213.A N LEU 209.A O no hydrogen 3.015 N/A VAL 214.A N VAL 210.A O no hydrogen 2.883 N/A GLY 215.A N GLU 211.A O no hydrogen 2.766 N/A TRP 219.A NE1 ARG 184.A O no hydrogen 2.890 N/A ARG 220.A N LEU 217.A O no hydrogen 3.208 N/A ARG 220.A NH1 LEU 217.A O no hydrogen 2.931 N/A ILE 222.A N TRP 219.A O no hydrogen 2.943 N/A LYS 225.A NZ PHE 179.A O no hydrogen 3.118 N/A GLN 227.A N ASP 224.A OD2 no hydrogen 3.058 N/A VAL 228.A N ASP 224.A O no hydrogen 3.083 N/A GLY 229.A N LYS 225.A O no hydrogen 3.051 N/A MET 230.A N GLU 226.A O no hydrogen 3.072 N/A ILE 231.A N GLN 227.A O no hydrogen 2.987 N/A LYS 232.A N VAL 228.A O no hydrogen 2.873 N/A LYS 232.A NZ VAL 183.A O no hydrogen 2.795 N/A LYS 232.A NZ ARG 184.A O no hydrogen 3.194 N/A LYS 232.A NZ ALA 186.A O no hydrogen 2.638 N/A LYS 232.A NZ HIS 191.A NE2 no hydrogen 2.960 N/A GLU 233.A N GLY 229.A O no hydrogen 2.954 N/A TYR 235.A N ILE 231.A O no hydrogen 3.156 N/A HIS 237.A ND1 TYR 235.A O no hydrogen 2.825 N/A HIS 237.A NE2 TYR 207.A OH no hydrogen 2.687 N/A ARG 238.A N GLU 236.A OE2 no hydrogen 3.012 N/A ARG 238.A NH1 HIS 249.A ND1 no hydrogen 3.036 N/A ARG 238.A NH1 ASP 253.A OD2 no hydrogen 3.076 N/A ARG 238.A NH2 ASP 253.A OD1 no hydrogen 2.646 N/A ARG 238.A NH2 ASP 253.A OD2 no hydrogen 3.194 N/A MET 239.A N GLU 236.A O no hydrogen 2.970 N/A LEU 240.A N HIS 237.A O no hydrogen 2.940 N/A LEU 241.A N ARG 238.A O no hydrogen 3.080 N/A LYS 242.A N MET 239.A O no hydrogen 3.294 N/A MET 244.A N LEU 241.A O no hydrogen 2.886 N/A PHE 248.A N PRO 245.A O no hydrogen 2.956 N/A HIS 249.A N SER 246.A O no hydrogen 3.059 N/A LEU 250.A N GLU 247.A O no hydrogen 2.962 N/A LEU 252.A N PHE 248.A O no hydrogen 2.955 N/A ASP 253.A N HIS 249.A O no hydrogen 2.888 N/A HIS 254.A N LEU 250.A O no hydrogen 2.996 N/A ILE 255.A N PHE 251.A O no hydrogen 2.982 N/A ALA 256.A N LEU 252.A O no hydrogen 2.914 N/A SER 257.A N HIS 254.A O no hydrogen 2.928 N/A SER 257.A OG HIS 254.A O no hydrogen 2.592 N/A LEU 258.A N ILE 255.A O no hydrogen 3.218 N/A TYR 260.A OH ARG 171.A O no hydrogen 2.768 N/A PHE 261.A N ASP 259.A OD1 no hydrogen 2.923 N/A THR 262.A N ASP 259.A O no hydrogen 3.295 N/A THR 262.A OG1 ASP 259.A OD1 no hydrogen 2.752 N/A ASP 265.A N HIS 254.A NE2 no hydrogen 2.893 N/A TYR 266.A OH HIS 126.A ND1 no hydrogen 2.607 N/A LEU 268.A N ASP 265.A OD1 no hydrogen 2.972 N/A ILE 269.A N ASP 265.A O no hydrogen 3.338 N/A MET 270.A N TYR 266.A O no hydrogen 2.773 N/A SER 271.A N GLN 267.A O no hydrogen 2.835 N/A SER 271.A OG.A GLN 267.A O no hydrogen 3.025 N/A SER 271.A OG.B GLN 267.A O no hydrogen 3.488 N/A SER 271.A OG.B LEU 268.A O no hydrogen 2.741 N/A VAL 272.A N LEU 268.A O no hydrogen 3.011 N/A PHE 273.A N ILE 269.A O no hydrogen 3.244 N/A GLU 274.A N MET 270.A O no hydrogen 2.885 N/A ASN 275.A N SER 271.A O no hydrogen 2.716 N/A ASN 275.A ND2 GLU 247.A OE1 no hydrogen 3.339 N/A SER 276.A N VAL 272.A O no hydrogen 3.029 N/A SER 276.A OG VAL 272.A O no hydrogen 2.728 N/A MET 277.A N PHE 273.A O no hydrogen 2.992 N/A LYS 278.A N GLU 274.A O no hydrogen 2.862 N/A GLU 279.A N ASN 275.A O no hydrogen 2.934 N/A ARG 280.A N MET 277.A O no hydrogen 2.948 N/A ARG 280.A NH1 SER 276.A O no hydrogen 2.846 N/A ARG 280.A NH1 GLU 279.A OE1 no hydrogen 3.238 N/A GLY 281.A N LYS 278.A O no hydrogen 3.176 N/A ILE 282.A N MET 277.A O no hydrogen 2.965 N/A ALA 283.A N GLU 286.A OE2 no hydrogen 3.317 N/A ASP 289.A N THR 110.A OG1 no hydrogen 3.037 N/A GLU 291.A N PHE 288.A O no hydrogen 3.115 N/A