Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7ziu_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 THR 1.A O no hydrogen 2.475 N/A ASN 2.A ND2 ASN 289.A OD1 no hydrogen 3.456 N/A MET 5.A N ASN 2.A O no hydrogen 3.224 N/A VAL 6.A N ASN 2.A O no hydrogen 3.451 N/A GLU 7.A N LYS 4.A O no hydrogen 3.507 N/A ARG 9.A NH1 CYS 164.A O no hydrogen 3.409 N/A ARG 9.A NH1 PHE 285.A O no hydrogen 2.347 N/A ARG 9.A NH1 ASN 289.A O no hydrogen 2.693 N/A ARG 9.A NH2 MET 5.A O no hydrogen 3.234 N/A ARG 9.A NH2 ASN 289.A O no hydrogen 2.819 N/A VAL 10.A N VAL 6.A O no hydrogen 3.386 N/A LYS 11.A N GLU 7.A O no hydrogen 3.243 N/A LYS 11.A NZ GLU 7.A OE2 no hydrogen 3.182 N/A LYS 12.A N ASP 8.A O no hydrogen 3.109 N/A LEU 13.A N ARG 9.A O no hydrogen 3.309 N/A ALA 14.A N VAL 10.A O no hydrogen 2.772 N/A ASP 15.A N LYS 11.A O no hydrogen 2.657 N/A GLU 16.A N LYS 12.A O no hydrogen 3.001 N/A PHE 17.A N LEU 13.A O no hydrogen 3.078 N/A SER 18.A N ASP 15.A O no hydrogen 3.339 N/A SER 18.A OG ASP 15.A O no hydrogen 3.164 N/A THR 20.A N PHE 17.A O no hydrogen 3.156 N/A THR 20.A OG1 PHE 17.A O no hydrogen 3.508 N/A HIS 22.A N SER 37.A O no hydrogen 2.751 N/A HIS 22.A ND1 THR 20.A O no hydrogen 2.818 N/A ASP 24.A N TYR 34.A OH no hydrogen 2.791 N/A GLU 26.A N ASP 24.A OD1 no hydrogen 2.720 N/A TYR 29.A N HIS 27.A ND1 no hydrogen 3.232 N/A TYR 29.A OH ASP 306.A OD2 no hydrogen 2.439 N/A LYS 30.A N ASP 83.A OD2 no hydrogen 2.913 N/A THR 31.A N ASP 83.A OD1 no hydrogen 2.943 N/A THR 31.A OG1 ASP 83.A OD1 no hydrogen 2.417 N/A ASN 33.A N SER 309.A O no hydrogen 3.292 N/A ASN 33.A ND2 ASN 2.A OD1 no hydrogen 3.322 N/A TYR 34.A OH SER 37.A OG no hydrogen 2.597 N/A HIS 35.A N VAL 307.A O no hydrogen 3.020 N/A HIS 35.A NE2 SER 309.A OG no hydrogen 2.945 N/A SER 37.A N HIS 22.A O no hydrogen 2.724 N/A SER 37.A OG TYR 34.A OH no hydrogen 2.597 N/A SER 37.A OG ASP 306.A OD1 no hydrogen 2.439 N/A TYR 38.A N MET 305.A O no hydrogen 2.938 N/A VAL 40.A N THR 303.A O no hydrogen 3.167 N/A THR 43.A OG1 LYS 41.A O no hydrogen 3.320 N/A SER 45.A OG SER 47.A OG no hydrogen 3.293 N/A SER 47.A OG SER 45.A OG no hydrogen 3.293 N/A MET 49.A N SER 458.A O no hydrogen 2.992 N/A ASN 51.A N ARG 456.A O no hydrogen 2.471 N/A ASN 51.A ND2 ALA 455.A O no hydrogen 3.386 N/A ASN 51.A ND2 SER 472.A OG no hydrogen 2.781 N/A VAL 54.A N ASN 51.A OD1 no hydrogen 3.299 N/A ARG 55.A N ASN 51.A O no hydrogen 2.762 N/A ARG 55.A NH1 ARG 55.A O no hydrogen 3.070 N/A VAL 56.A N GLY 52.A O no hydrogen 3.088 N/A SER 58.A N ARG 55.A O no hydrogen 3.260 N/A SER 58.A OG VAL 54.A O no hydrogen 2.484 N/A LYS 59.A NZ VAL 56.A O no hydrogen 3.569 N/A TRP 61.A N SER 58.A O no hydrogen 3.031 N/A ASP 62.A N LYS 59.A O no hydrogen 3.046 N/A THR 70.A N ASP 68.A OD1 no hydrogen 3.398 N/A THR 70.A OG1 ASP 68.A OD1 no hydrogen 2.742 N/A GLN 74.A N THR 70.A O no hydrogen 2.844 N/A GLN 74.A NE2 THR 69.A O no hydrogen 3.099 N/A GLN 75.A N PRO 71.A O no hydrogen 3.325 N/A ARG 76.A N PHE 72.A O no hydrogen 3.113 N/A VAL 77.A N GLY 73.A O no hydrogen 3.348 N/A PHE 78.A N GLN 74.A O no hydrogen 3.263 N/A LYS 79.A N GLN 75.A O no hydrogen 2.827 N/A GLU 80.A N ARG 76.A O no hydrogen 3.090 N/A LYS 81.A N VAL 77.A O no hydrogen 2.845 N/A VAL 82.A N VAL 77.A O no hydrogen 3.194 N/A ASP 83.A N PHE 78.A O no hydrogen 2.776 N/A THR 84.A N VAL 82.A O no hydrogen 2.792 N/A LYS 85.A NZ ALA 86.A O no hydrogen 3.055 N/A LYS 85.A NZ GLU 88.A OE2 no hydrogen 2.784 N/A LYS 85.A NZ ASP 312.A OD2 no hydrogen 3.374 N/A GLY 92.A N GLU 350.A O no hydrogen 3.168 N/A THR 93.A N VAL 349.A O no hydrogen 2.973 N/A THR 93.A OG1 VAL 349.A O no hydrogen 3.403 N/A ALA 94.A N PRO 90.A O no hydrogen 2.938 N/A GLU 95.A N LYS 91.A O no hydrogen 3.290 N/A VAL 96.A N GLY 92.A O no hydrogen 3.495 N/A MET 97.A N THR 93.A O no hydrogen 2.980 N/A ARG 98.A N ALA 94.A O no hydrogen 2.785 N/A VAL 99.A N GLU 95.A O no hydrogen 2.850 N/A THR 100.A N VAL 96.A O no hydrogen 3.023 N/A THR 100.A OG1 VAL 96.A O no hydrogen 2.794 N/A ALA 101.A N MET 97.A O no hydrogen 2.892 N/A LYS 102.A N ARG 98.A O no hydrogen 3.092 N/A TRP 103.A N VAL 99.A O no hydrogen 3.050 N/A TRP 103.A NE1 ASP 365.A OD1 no hydrogen 2.749 N/A MET 104.A N THR 100.A O no hydrogen 2.873 N/A TRP 105.A N ALA 101.A O no hydrogen 2.886 N/A TRP 105.A NE1 ASN 263.A O no hydrogen 3.023 N/A LYS 106.A N LYS 102.A O no hydrogen 3.117 N/A PHE 107.A N TRP 103.A O no hydrogen 2.899 N/A VAL 108.A N MET 104.A O no hydrogen 2.726 N/A GLY 109.A N TRP 105.A O no hydrogen 3.138 N/A ARG 110.A N PHE 107.A O no hydrogen 3.327 N/A ARG 110.A NH1 PHE 107.A O no hydrogen 3.158 N/A ARG 110.A NH1 ASN 216.A O no hydrogen 2.560 N/A ARG 110.A NH2 ASN 216.A O no hydrogen 3.139 N/A LYS 112.A NZ ASP 209.A O no hydrogen 2.483 N/A LYS 112.A NZ HIS 210.A O no hydrogen 2.373 N/A ARG 115.A NE ASP 209.A OD1 no hydrogen 3.168 N/A ARG 115.A NE ASP 209.A OD2 no hydrogen 2.985 N/A ARG 115.A NH1 GLU 121.A OE1 no hydrogen 3.502 N/A ARG 115.A NH2 GLU 121.A OE1 no hydrogen 3.359 N/A ARG 115.A NH2 ASP 209.A OD1 no hydrogen 2.851 N/A CYS 117.A N GLU 201.A O no hydrogen 3.015 N/A THR 118.A OG1 GLU 120.A OE1 no hydrogen 3.342 N/A GLU 120.A N GLU 120.A OE1 no hydrogen 2.747 N/A PHE 122.A N THR 118.A O no hydrogen 3.301 N/A ILE 123.A N LYS 119.A O no hydrogen 2.636 N/A ALA 124.A N GLU 120.A O no hydrogen 2.912 N/A LYS 125.A N GLU 121.A O no hydrogen 3.126 N/A LYS 125.A N PHE 122.A O no hydrogen 3.188 N/A VAL 126.A N PHE 122.A O no hydrogen 3.202 N/A ASN 127.A N ILE 123.A O no hydrogen 3.237 N/A SER 128.A N ALA 124.A O no hydrogen 3.125 N/A SER 128.A N LYS 125.A O no hydrogen 3.160 N/A SER 128.A OG ALA 124.A O no hydrogen 2.913 N/A TRP 133.A NE1 ASP 142.A OD2 no hydrogen 2.758 N/A ARG 137.A NE ASN 127.A OD1 no hydrogen 3.253 N/A ALA 139.A N SER 135.A O no hydrogen 3.134 N/A VAL 140.A N ALA 136.A O no hydrogen 3.307 N/A ASP 142.A N ALA 139.A O no hydrogen 2.921 N/A ALA 144.A N ASP 142.A OD1 no hydrogen 3.115 N/A PHE 145.A N ASP 142.A O no hydrogen 3.032 N/A TRP 146.A NE1 VAL 140.A O no hydrogen 2.892 N/A GLU 147.A N PRO 143.A O no hydrogen 3.300 N/A MET 148.A N ALA 144.A O no hydrogen 3.403 N/A VAL 149.A N PHE 145.A O no hydrogen 3.176 N/A ASP 150.A N TRP 146.A O no hydrogen 2.775 N/A ARG 151.A N GLU 147.A O no hydrogen 2.838 N/A GLU 152.A N MET 148.A O no hydrogen 3.129 N/A ARG 153.A N VAL 149.A O no hydrogen 2.722 N/A GLU 154.A N ASP 150.A O no hydrogen 2.670 N/A ALA 155.A N ARG 151.A O no hydrogen 3.013 N/A HIS 156.A N GLU 152.A O no hydrogen 3.147 N/A LEU 157.A N ARG 153.A O no hydrogen 3.180 N/A GLN 158.A N GLU 154.A O no hydrogen 3.060 N/A GLN 158.A N ALA 155.A O no hydrogen 3.022 N/A GLY 159.A N HIS 156.A O no hydrogen 2.988 N/A ARG 160.A N ALA 155.A O no hydrogen 2.690 N/A ARG 160.A NE GLN 158.A OE1 no hydrogen 3.498 N/A ARG 160.A NH1 GLU 162.A OE2 no hydrogen 2.836 N/A ARG 160.A NH2 GLN 158.A OE1 no hydrogen 3.456 N/A CYS 161.A SG GLU 152.A OE2 no hydrogen 3.637 N/A CYS 161.A SG HIS 156.A NE2 no hydrogen 4.014 N/A GLU 162.A N GLU 152.A OE2 no hydrogen 2.891 N/A MET 163.A N GLU 152.A OE2 no hydrogen 3.122 N/A CYS 164.A SG GLU 152.A OE2 no hydrogen 3.882 N/A CYS 164.A SG HIS 156.A NE2 no hydrogen 3.530 N/A CYS 164.A SG SER 195.A OG no hydrogen 3.455 N/A THR 165.A N MET 163.A O no hydrogen 2.704 N/A THR 165.A OG1 MET 163.A O no hydrogen 3.464 N/A TYR 166.A N VAL 291.A O no hydrogen 2.631 N/A ASN 167.A N TYR 190.A O no hydrogen 2.583 N/A MET 168.A N LYS 293.A O no hydrogen 2.856 N/A LYS 171.A N ASP 68.A O no hydrogen 3.100 N/A ARG 172.A N ARG 186.A O no hydrogen 3.095 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.649 N/A LYS 175.A N LYS 183.A O no hydrogen 2.924 N/A SER 185.A OG GLU 80.A OE2 no hydrogen 2.694 N/A ILE 188.A N GLY 170.A O no hydrogen 3.142 N/A TYR 190.A N ASN 167.A O no hydrogen 2.870 N/A ARG 196.A N TRP 192.A O no hydrogen 2.875 N/A ARG 196.A NH1 GLY 317.A O no hydrogen 2.291 N/A ARG 196.A NH2 TRP 189.A O no hydrogen 3.364 N/A TYR 197.A N LEU 193.A O no hydrogen 3.046 N/A TYR 197.A OH GLU 201.A OE2 no hydrogen 3.133 N/A LEU 198.A N GLY 194.A O no hydrogen 3.157 N/A GLU 199.A N SER 195.A O no hydrogen 2.923 N/A PHE 200.A N ARG 196.A O no hydrogen 2.823 N/A GLU 201.A N TYR 197.A O no hydrogen 2.383 N/A ALA 202.A N LEU 198.A O no hydrogen 3.042 N/A LEU 203.A N GLU 199.A O no hydrogen 2.820 N/A GLY 204.A N PHE 200.A O no hydrogen 2.839 N/A LEU 206.A N LEU 203.A O no hydrogen 3.299 N/A ASN 207.A N GLY 204.A O no hydrogen 2.993 N/A ASN 207.A ND2 VAL 319.A O no hydrogen 2.652 N/A GLU 208.A N GLY 204.A O no hydrogen 2.935 N/A ASP 209.A N PHE 205.A O no hydrogen 3.157 N/A HIS 210.A N ASN 207.A O no hydrogen 3.136 N/A TRP 211.A N LEU 206.A O no hydrogen 3.133 N/A SER 213.A N HIS 210.A O no hydrogen 3.395 N/A SER 213.A OG HIS 210.A O no hydrogen 3.024 N/A ARG 214.A NH1 GLY 220.A O no hydrogen 3.122 N/A ARG 214.A NH1 MET 375.A O no hydrogen 3.038 N/A ARG 214.A NH2 MET 375.A O no hydrogen 2.973 N/A GLU 215.A N GLU 215.A OE1 no hydrogen 2.819 N/A ASN 216.A N SER 213.A O no hydrogen 2.970 N/A ASN 216.A ND2 VAL 108.A O no hydrogen 3.426 N/A THR 217.A N SER 213.A O no hydrogen 2.897 N/A THR 217.A OG1 MET 212.A O no hydrogen 3.389 N/A THR 217.A OG1 SER 213.A O no hydrogen 3.074 N/A LEU 218.A N ARG 214.A O no hydrogen 2.980 N/A GLY 220.A N THR 217.A OG1 no hydrogen 2.854 N/A LEU 224.A N VAL 221.A O no hydrogen 3.196 N/A LEU 226.A N HIS 515.A O no hydrogen 3.073 N/A GLN 227.A N GLN 227.A OE1 no hydrogen 2.607 N/A GLN 227.A NE2 GLU 519.A OE2 no hydrogen 3.035 N/A LYS 228.A N GLY 225.A O no hydrogen 3.060 N/A LYS 228.A NZ GLU 539.A OE1 no hydrogen 3.176 N/A LYS 228.A NZ GLU 539.A OE2 no hydrogen 3.529 N/A LEU 229.A N LEU 226.A O no hydrogen 3.391 N/A LEU 233.A N LEU 229.A O no hydrogen 3.379 N/A ARG 234.A N GLY 230.A O no hydrogen 3.358 N/A ASP 235.A N TYR 231.A O no hydrogen 2.936 N/A ILE 236.A N VAL 232.A O no hydrogen 2.976 N/A ALA 237.A N LEU 233.A O no hydrogen 3.041 N/A LYS 238.A N ARG 234.A O no hydrogen 3.256 N/A LYS 238.A N ASP 235.A O no hydrogen 3.259 N/A ASN 239.A N ILE 236.A O no hydrogen 3.023 N/A ASN 239.A ND2 SER 374.A OG no hydrogen 3.217 N/A GLY 242.A N PRO 386.A O no hydrogen 3.201 N/A LEU 243.A N ASP 389.A OD1 no hydrogen 3.056 N/A MET 244.A N TRP 417.A O no hydrogen 3.125 N/A TYR 245.A N VAL 384.A O no hydrogen 3.001 N/A TYR 245.A OH ASP 389.A OD1 no hydrogen 3.096 N/A TRP 252.A NE1 ASN 325.A OD1 no hydrogen 2.539 N/A THR 254.A OG1 GLY 251.A O no hydrogen 2.558 N/A ARG 255.A N TRP 252.A O no hydrogen 2.965 N/A THR 257.A N ASP 260.A OD2 no hydrogen 3.022 N/A THR 257.A OG1 ASP 260.A OD2 no hydrogen 2.909 N/A LYS 258.A N GLU 88.A OE2 no hydrogen 2.929 N/A ALA 259.A N GLU 88.A OE1 no hydrogen 3.329 N/A ASP 260.A N THR 257.A OG1 no hydrogen 3.192 N/A LEU 261.A N THR 257.A O no hydrogen 3.216 N/A GLU 262.A N LYS 258.A O no hydrogen 3.058 N/A ASN 263.A N ALA 259.A O no hydrogen 2.775 N/A GLU 264.A N ASP 260.A O no hydrogen 2.968 N/A SER 265.A N LEU 261.A O no hydrogen 2.862 N/A SER 265.A N GLU 262.A O no hydrogen 3.000 N/A SER 265.A OG LEU 261.A O no hydrogen 2.593 N/A LEU 268.A N SER 265.A O no hydrogen 3.302 N/A GLU 269.A N ILE 266.A O no hydrogen 3.164 N/A MET 270.A N VAL 267.A O no hydrogen 2.788 N/A MET 271.A N LEU 268.A O no hydrogen 3.117 N/A THR 272.A OG1 GLU 274.A OE1 no hydrogen 3.333 N/A HIS 275.A N THR 272.A OG1 no hydrogen 3.145 N/A HIS 275.A NE2 ALA 202.A O no hydrogen 2.790 N/A ARG 276.A N THR 272.A O no hydrogen 2.702 N/A ALA 277.A N PRO 273.A O no hydrogen 2.763 N/A LEU 278.A N HIS 275.A O no hydrogen 3.112 N/A ALA 279.A N HIS 275.A O no hydrogen 3.088 N/A GLU 280.A N ARG 276.A O no hydrogen 2.804 N/A ILE 283.A N ALA 279.A O no hydrogen 3.072 N/A LYS 284.A N GLU 280.A O no hydrogen 3.246 N/A PHE 285.A N PRO 281.A O no hydrogen 2.902 N/A ALA 286.A N LEU 282.A O no hydrogen 2.595 N/A TYR 287.A N ILE 283.A O no hydrogen 3.212 N/A TYR 287.A OH GLU 199.A OE2 no hydrogen 2.384 N/A MET 288.A N ILE 283.A O no hydrogen 2.894 N/A ASN 289.A ND2 LYS 284.A O no hydrogen 2.948 N/A LYS 290.A NZ TYR 287.A O no hydrogen 2.930 N/A LYS 290.A NZ GLN 318.A OE1 no hydrogen 3.372 N/A VAL 292.A N ILE 308.A O no hydrogen 3.035 N/A LYS 293.A N TYR 166.A O no hydrogen 2.867 N/A VAL 294.A N ASP 306.A O no hydrogen 3.110 N/A MET 295.A N GLN 74.A OE1 no hydrogen 3.134 N/A ARG 296.A N VAL 304.A O no hydrogen 2.791 N/A ARG 296.A NH1 ASP 306.A OD2 no hydrogen 2.669 N/A ILE 302.A N ALA 299.A O no hydrogen 3.145 N/A THR 303.A OG1 VAL 40.A O no hydrogen 2.266 N/A VAL 304.A N ARG 296.A O no hydrogen 3.194 N/A MET 305.A N TYR 38.A O no hydrogen 2.631 N/A ASP 306.A N VAL 294.A O no hydrogen 2.727 N/A VAL 307.A N GLY 36.A O no hydrogen 3.071 N/A ILE 308.A N VAL 292.A O no hydrogen 3.150 N/A SER 309.A N ASN 33.A O no hydrogen 3.294 N/A SER 309.A OG ASN 33.A OD1 no hydrogen 2.255 N/A SER 309.A OG HIS 35.A NE2 no hydrogen 2.945 N/A ARG 310.A NH1 THR 84.A O no hydrogen 2.759 N/A ARG 310.A NH2 THR 84.A O no hydrogen 2.638 N/A GLN 313.A NE2 VAL 82.A O no hydrogen 2.860 N/A ARG 314.A N ASP 253.A O no hydrogen 3.400 N/A ARG 314.A NH2 GLU 264.A OE1 no hydrogen 2.847 N/A GLY 315.A N GLN 318.A OE1 no hydrogen 2.653 N/A SER 316.A OG ASP 253.A OD2 no hydrogen 2.620 N/A SER 316.A OG ARG 314.A O no hydrogen 3.304 N/A VAL 319.A N GLU 199.A OE2 no hydrogen 2.565 N/A THR 321.A N GLN 318.A O no hydrogen 2.900 N/A THR 321.A OG1 GLN 318.A O no hydrogen 2.640 N/A TYR 322.A OH SER 378.A OG no hydrogen 2.865 N/A LEU 324.A N VAL 320.A O no hydrogen 2.900 N/A ASN 325.A N THR 321.A O no hydrogen 3.010 N/A ASN 325.A ND2 ASP 253.A OD1 no hydrogen 3.252 N/A THR 326.A N TYR 322.A O no hydrogen 2.960 N/A THR 326.A OG1 TYR 322.A O no hydrogen 2.959 N/A PHE 327.A N ALA 323.A O no hydrogen 3.060 N/A THR 328.A N LEU 324.A O no hydrogen 2.981 N/A THR 328.A OG1 GLU 264.A OE2 no hydrogen 2.222 N/A THR 328.A OG1 LEU 324.A O no hydrogen 3.421 N/A ASN 329.A N ASN 325.A O no hydrogen 2.895 N/A ASN 329.A ND2 GLY 379.A O no hydrogen 3.034 N/A LEU 330.A N THR 326.A O no hydrogen 2.955 N/A CYS 331.A N PHE 327.A O no hydrogen 3.059 N/A CYS 331.A SG PHE 327.A O no hydrogen 3.390 N/A VAL 332.A N THR 328.A O no hydrogen 2.722 N/A GLN 333.A N ASN 329.A O no hydrogen 2.894 N/A GLN 333.A NE2 ASN 329.A OD1 no hydrogen 3.141 N/A LEU 334.A N LEU 330.A O no hydrogen 3.034 N/A ILE 335.A N CYS 331.A O no hydrogen 2.922 N/A ARG 336.A N VAL 332.A O no hydrogen 3.037 N/A ARG 336.A NE PHE 391.A O no hydrogen 3.179 N/A ARG 336.A NH1 ASP 247.A OD2 no hydrogen 3.135 N/A ARG 336.A NH2 PHE 391.A O no hydrogen 3.078 N/A ARG 336.A NH2 ALA 392.A O no hydrogen 3.393 N/A ARG 336.A NH2 SER 414.A OG no hydrogen 3.073 N/A CYS 337.A N GLN 333.A O no hydrogen 2.977 N/A CYS 337.A SG GLN 333.A O no hydrogen 3.199 N/A MET 338.A N LEU 334.A O no hydrogen 3.135 N/A GLU 339.A N ILE 335.A O no hydrogen 3.196 N/A GLY 340.A N ARG 336.A O no hydrogen 2.998 N/A GLU 341.A N CYS 337.A O no hydrogen 3.067 N/A GLY 342.A N GLU 339.A O no hydrogen 3.176 N/A LEU 343.A N MET 338.A O no hydrogen 3.014 N/A LYS 345.A N GLU 348.A OE1 no hydrogen 2.934 N/A LYS 345.A NZ GLY 342.A O no hydrogen 3.200 N/A GLU 348.A N LYS 345.A O no hydrogen 3.189 N/A GLU 350.A N GLU 347.A O no hydrogen 3.325 N/A GLU 353.A N GLU 348.A OE2 no hydrogen 3.101 N/A LYS 359.A N GLY 355.A O no hydrogen 3.302 N/A GLN 361.A N GLN 357.A O no hydrogen 3.222 N/A ASP 362.A N ARG 358.A O no hydrogen 2.721 N/A TRP 363.A N LYS 359.A O no hydrogen 2.855 N/A TRP 363.A NE1 GLU 341.A OE1 no hydrogen 2.777 N/A LEU 364.A N ILE 360.A O no hydrogen 2.947 N/A ASP 365.A N GLN 361.A O no hydrogen 2.826 N/A LYS 366.A N ASP 362.A O no hydrogen 3.025 N/A ASN 367.A N TRP 363.A O no hydrogen 2.644 N/A GLY 368.A N LEU 364.A O no hydrogen 2.859 N/A ARG 371.A N ASN 367.A O no hydrogen 2.885 N/A ARG 371.A NH1 LYS 385.A O no hydrogen 3.241 N/A LEU 372.A N GLY 368.A O no hydrogen 2.983 N/A ALA 373.A N THR 369.A O no hydrogen 3.123 N/A SER 374.A N ARG 371.A O no hydrogen 3.295 N/A MET 375.A N LEU 372.A O no hydrogen 2.955 N/A ALA 376.A N VAL 383.A O no hydrogen 2.773 N/A VAL 377.A N GLY 219.A O no hydrogen 2.839 N/A SER 378.A N ASP 381.A O no hydrogen 2.809 N/A SER 378.A OG TYR 322.A OH no hydrogen 2.865 N/A SER 378.A OG HIS 515.A NE2 no hydrogen 2.658 N/A GLY 379.A N THR 326.A OG1 no hydrogen 3.166 N/A ASP 380.A N ASP 380.A OD1 no hydrogen 2.539 N/A ASP 381.A N SER 378.A O no hydrogen 3.001 N/A CYS 382.A SG ASP 247.A O no hydrogen 3.347 N/A VAL 383.A N ALA 376.A O no hydrogen 2.772 N/A VAL 384.A N TYR 245.A O no hydrogen 2.941 N/A LYS 385.A N SER 374.A O no hydrogen 2.958 N/A LYS 385.A NZ GLY 242.A O no hydrogen 2.339 N/A ARG 390.A N ASP 388.A OD1 no hydrogen 3.359 N/A ARG 390.A NE ASP 388.A OD2 no hydrogen 2.639 N/A ARG 390.A NH2 ASP 388.A OD2 no hydrogen 2.596 N/A ALA 392.A N ASP 389.A O no hydrogen 3.261 N/A THR 393.A N ARG 390.A O no hydrogen 3.224 N/A THR 393.A OG1 ARG 390.A O no hydrogen 3.164 N/A ALA 394.A N PHE 391.A O no hydrogen 3.421 N/A HIS 396.A N GLU 339.A OE2 no hydrogen 3.073 N/A PHE 397.A N GLU 339.A OE1 no hydrogen 2.816 N/A ASN 399.A N LEU 395.A O no hydrogen 3.103 N/A ASN 399.A ND2 GLU 410.A O no hydrogen 2.929 N/A SER 400.A N HIS 396.A O no hydrogen 2.931 N/A SER 400.A OG HIS 396.A O no hydrogen 2.500 N/A MET 401.A N PHE 397.A O no hydrogen 3.083 N/A MET 401.A N LEU 398.A O no hydrogen 3.290 N/A SER 402.A N ASN 399.A O no hydrogen 3.179 N/A SER 402.A OG PRO 87.A O no hydrogen 2.534 N/A LYS 403.A N LEU 398.A O no hydrogen 3.266 N/A LYS 403.A NZ ARG 255.A O no hydrogen 2.555 N/A LYS 403.A NZ ASP 260.A OD2 no hydrogen 2.977 N/A ARG 405.A NH1 LYS 412.A O no hydrogen 2.878 N/A ARG 405.A NH1 SER 414.A OG no hydrogen 2.319 N/A ARG 405.A NH2 GLU 410.A O no hydrogen 3.053 N/A ARG 405.A NH2 LYS 412.A O no hydrogen 2.660 N/A LYS 406.A N ASP 248.A O no hydrogen 2.713 N/A LYS 412.A N PRO 409.A O no hydrogen 3.472 N/A SER 414.A N ALA 392.A O no hydrogen 3.369 N/A SER 414.A OG ASP 247.A OD2 no hydrogen 3.158 N/A TRP 417.A N MET 244.A O no hydrogen 2.679 N/A GLN 421.A N ASN 419.A OD1 no hydrogen 2.816 N/A ASP 422.A N ASN 419.A O no hydrogen 3.101 N/A VAL 423.A N TRP 420.A O no hydrogen 3.251 N/A PHE 425.A N HIS 428.A O no hydrogen 2.779 N/A HIS 428.A N PHE 425.A O no hydrogen 2.941 N/A HIS 428.A ND1 CYS 426.A O no hydrogen 2.813 N/A HIS 428.A NE2 TYR 483.A OH no hydrogen 2.620 N/A HIS 429.A N CYS 445.A O no hydrogen 2.841 N/A HIS 431.A N VAL 443.A O no hydrogen 3.030 N/A GLU 432.A N GLN 421.A OE1 no hydrogen 3.302 N/A LEU 433.A N ILE 441.A O no hydrogen 2.953 N/A MET 435.A N ARG 439.A O no hydrogen 2.582 N/A GLY 438.A N MET 435.A O no hydrogen 3.116 N/A ARG 439.A N ASP 437.A OD1 no hydrogen 2.989 N/A ARG 439.A NE ASP 437.A OD1 no hydrogen 3.042 N/A ARG 439.A NH1 ASP 543.A O no hydrogen 3.328 N/A ARG 439.A NH1 THR 545.A O no hydrogen 2.574 N/A ARG 439.A NH2 ASP 437.A OD2 no hydrogen 3.024 N/A GLN 440.A NE2 THR 434.A OG1 no hydrogen 3.148 N/A ILE 441.A N LEU 433.A O no hydrogen 2.920 N/A VAL 442.A N TYR 231.A OH no hydrogen 3.314 N/A VAL 443.A N HIS 431.A O no hydrogen 2.988 N/A CYS 445.A N HIS 429.A O no hydrogen 2.658 N/A CYS 445.A SG HIS 429.A NE2 no hydrogen 3.204 N/A CYS 445.A SG ARG 446.A O no hydrogen 3.778 N/A ARG 446.A NE GLU 450.A OE1 no hydrogen 2.709 N/A ARG 446.A NH2 GLU 450.A OE1 no hydrogen 2.653 N/A GLN 448.A N CYS 564.A O no hydrogen 2.991 N/A GLN 448.A NE2 ASP 488.A OD2 no hydrogen 2.829 N/A ASP 449.A N HIS 447.A ND1 no hydrogen 3.188 N/A GLU 450.A N HIS 447.A O no hydrogen 3.158 N/A ILE 452.A N GLN 448.A O no hydrogen 3.077 N/A GLY 453.A N ASP 449.A O no hydrogen 2.881 N/A ARG 454.A N GLU 450.A O no hydrogen 3.410 N/A ARG 454.A NH1 ARG 509.A O no hydrogen 3.026 N/A ARG 456.A N ILE 452.A O no hydrogen 3.194 N/A ARG 456.A NE SER 58.A OG no hydrogen 3.302 N/A ARG 456.A NH2 SER 58.A O no hydrogen 3.513 N/A LEU 457.A N ARG 454.A O no hydrogen 3.357 N/A SER 458.A N MET 49.A O no hydrogen 2.563 N/A TRP 463.A NE1 PRO 459.A O no hydrogen 3.152 N/A SER 464.A N GLU 467.A OE1 no hydrogen 3.432 N/A GLU 467.A N SER 464.A OG no hydrogen 3.241 N/A THR 468.A N SER 464.A O no hydrogen 2.944 N/A THR 468.A OG1 ASN 51.A OD1 no hydrogen 3.095 N/A ALA 469.A N LEU 465.A O no hydrogen 2.894 N/A CYS 470.A N THR 466.A O no hydrogen 3.208 N/A CYS 470.A SG THR 466.A O no hydrogen 3.311 N/A CYS 470.A SG VAL 505.A O no hydrogen 3.294 N/A LEU 471.A N GLU 467.A O no hydrogen 3.213 N/A SER 472.A N THR 468.A O no hydrogen 3.184 N/A SER 472.A OG THR 468.A O no hydrogen 2.810 N/A LYS 473.A N ALA 469.A O no hydrogen 2.869 N/A LYS 473.A NZ TRP 504.A O no hydrogen 2.639 N/A ALA 474.A N CYS 470.A O no hydrogen 2.870 N/A TYR 475.A N LEU 471.A O no hydrogen 3.036 N/A GLY 476.A N SER 472.A O no hydrogen 2.919 N/A GLN 477.A N LYS 473.A O no hydrogen 2.855 N/A GLN 477.A NE2 TRP 520.A O no hydrogen 2.567 N/A GLN 477.A NE2 THR 522.A O no hydrogen 2.837 N/A MET 478.A N ALA 474.A O no hydrogen 2.971 N/A TRP 479.A N TYR 475.A O no hydrogen 2.942 N/A LEU 480.A N GLY 476.A O no hydrogen 3.114 N/A LEU 481.A N GLN 477.A O no hydrogen 3.209 N/A LEU 481.A N MET 478.A O no hydrogen 3.178 N/A MET 482.A N MET 478.A O no hydrogen 2.980 N/A TYR 483.A N TRP 479.A O no hydrogen 2.705 N/A TYR 483.A OH HIS 428.A NE2 no hydrogen 2.620 N/A HIS 485.A NE2 PRO 444.A O no hydrogen 2.666 N/A ARG 486.A N TYR 483.A O no hydrogen 3.083 N/A ARG 486.A NE ASP 561.A OD1 no hydrogen 2.587 N/A ARG 486.A NH1 ARG 446.A O no hydrogen 2.857 N/A ARG 486.A NH2 ASP 561.A O no hydrogen 3.353 N/A ARG 486.A NH2 ASP 561.A OD1 no hydrogen 2.837 N/A ARG 486.A NH2 CYS 564.A O no hydrogen 2.946 N/A ARG 487.A N ASP 561.A OD2 no hydrogen 3.342 N/A ARG 487.A NH1 ASP 561.A OD2 no hydrogen 3.142 N/A ARG 490.A N ARG 486.A O no hydrogen 2.983 N/A ARG 490.A NH1 PHE 484.A O no hydrogen 3.402 N/A ARG 490.A NH1 VAL 553.A O no hydrogen 3.098 N/A ARG 490.A NH2 VAL 553.A O no hydrogen 3.517 N/A LEU 491.A N ARG 487.A O no hydrogen 3.179 N/A MET 492.A N ASP 488.A O no hydrogen 2.879 N/A ALA 493.A N LEU 489.A O no hydrogen 2.629 N/A ASN 494.A N ARG 490.A O no hydrogen 3.155 N/A ALA 495.A N LEU 491.A O no hydrogen 3.066 N/A ILE 496.A N MET 492.A O no hydrogen 3.069 N/A CYS 497.A N ALA 493.A O no hydrogen 3.087 N/A CYS 497.A SG ALA 493.A O no hydrogen 3.274 N/A SER 498.A N ASN 494.A O no hydrogen 2.655 N/A SER 498.A OG ASN 494.A O no hydrogen 2.856 N/A SER 498.A OG VAL 597.A O no hydrogen 3.545 N/A ALA 499.A N ALA 495.A O no hydrogen 2.828 N/A VAL 500.A N ILE 496.A O no hydrogen 2.629 N/A VAL 502.A N ARG 595.A O no hydrogen 3.413 N/A THR 507.A N CYS 470.A O no hydrogen 3.442 N/A ARG 509.A NH1 THR 511.A O no hydrogen 3.193 N/A SER 513.A N THR 511.A OG1 no hydrogen 3.238 N/A HIS 515.A N SER 513.A OG no hydrogen 3.311 N/A HIS 515.A ND1 LEU 224.A O no hydrogen 2.689 N/A HIS 515.A NE2 SER 378.A OG no hydrogen 2.658 N/A GLY 516.A N SER 513.A O no hydrogen 3.174 N/A GLU 519.A N GLU 519.A OE1 no hydrogen 2.592 N/A TRP 520.A NE1 THR 510.A OG1 no hydrogen 3.092 N/A MET 521.A N GLY 518.A O no hydrogen 3.133 N/A GLU 524.A N THR 522.A OG1 no hydrogen 3.333 N/A LEU 527.A N ASP 525.A OD1 no hydrogen 3.315 N/A VAL 529.A N ASP 525.A O no hydrogen 3.165 N/A TRP 530.A N MET 526.A O no hydrogen 2.656 N/A ASN 531.A N LEU 527.A O no hydrogen 3.069 N/A ASN 531.A ND2 LEU 527.A O no hydrogen 2.747 N/A ASN 531.A ND2 VAL 547.A O no hydrogen 3.305 N/A ARG 532.A N ARG 528.A O no hydrogen 3.169 N/A ARG 532.A NH2 GLU 524.A OE2 no hydrogen 3.542 N/A VAL 533.A N VAL 529.A O no hydrogen 2.868 N/A TRP 534.A N TRP 530.A O no hydrogen 2.907 N/A TRP 534.A NE1 LEU 481.A O no hydrogen 2.788 N/A ILE 535.A N ASN 531.A O no hydrogen 2.988 N/A GLU 536.A N ASN 531.A O no hydrogen 2.932 N/A GLU 537.A N ARG 532.A O no hydrogen 2.732 N/A ASN 538.A ND2 TYR 231.A OH no hydrogen 2.792 N/A ASN 538.A ND2 TRP 534.A O no hydrogen 3.073 N/A GLU 539.A N GLU 539.A OE1 no hydrogen 2.724 N/A HIS 540.A N ASN 538.A OD1 no hydrogen 2.747 N/A HIS 540.A NE2 ASP 235.A OD2 no hydrogen 3.336 N/A MET 541.A N ASN 538.A O no hydrogen 3.259 N/A LYS 544.A NZ ILE 535.A O no hydrogen 2.790 N/A LYS 544.A NZ GLU 536.A O no hydrogen 3.519 N/A LYS 544.A NZ MET 541.A O no hydrogen 2.835 N/A THR 545.A N ASP 543.A OD1 no hydrogen 3.331 N/A VAL 547.A N ASN 531.A OD1 no hydrogen 2.576 N/A SER 548.A OG ASP 552.A OD2 no hydrogen 3.077 N/A ASN 551.A N SER 549.A OG no hydrogen 3.274 N/A ASN 551.A ND2 SER 549.A OG no hydrogen 3.214 N/A ASN 551.A ND2 THR 602.A O no hydrogen 3.637 N/A ASP 552.A N SER 549.A O no hydrogen 3.100 N/A VAL 553.A N TRP 550.A O no hydrogen 3.016 N/A LEU 556.A N HIS 485.A O no hydrogen 2.881 N/A GLY 557.A N GLU 560.A OE1 no hydrogen 3.176 N/A ASP 561.A N GLY 557.A O no hydrogen 2.574 N/A SER 562.A N LYS 558.A O no hydrogen 2.911 N/A TRP 563.A N ARG 559.A O no hydrogen 3.045 N/A CYS 564.A N GLU 560.A O no hydrogen 3.273 N/A CYS 564.A SG HIS 429.A NE2 no hydrogen 3.356 N/A CYS 564.A SG HIS 431.A NE2 no hydrogen 3.713 N/A CYS 564.A SG GLU 560.A O no hydrogen 3.533 N/A GLY 565.A N SER 562.A O no hydrogen 3.255 N/A SER 566.A N ASP 561.A O no hydrogen 3.024 N/A SER 566.A OG ASP 488.A OD1 no hydrogen 3.070 N/A SER 566.A OG ASP 488.A OD2 no hydrogen 3.259 N/A SER 566.A OG ASP 561.A OD2 no hydrogen 3.533 N/A LEU 567.A N ASP 488.A OD2 no hydrogen 2.841 N/A ILE 568.A N SER 566.A OG no hydrogen 3.429 N/A HIS 570.A N LEU 567.A O no hydrogen 3.316 N/A SER 574.A N HIS 570.A O no hydrogen 3.250 N/A SER 574.A OG HIS 570.A O no hydrogen 3.113 N/A THR 575.A N ARG 571.A O no hydrogen 3.205 N/A THR 575.A OG1 ARG 571.A O no hydrogen 3.349 N/A TRP 576.A N ALA 572.A O no hydrogen 3.063 N/A TRP 576.A NE1 LEU 57.A O no hydrogen 2.807 N/A ALA 577.A N ARG 573.A O no hydrogen 2.792 N/A GLU 578.A N SER 574.A O no hydrogen 3.129 N/A ASN 579.A N THR 575.A O no hydrogen 3.135 N/A ASN 579.A ND2 THR 575.A O no hydrogen 2.747 N/A ILE 580.A N ALA 577.A O no hydrogen 3.421 N/A TYR 581.A OH ASP 598.A OD2 no hydrogen 2.601 N/A THR 582.A N ASN 579.A O no hydrogen 3.252 N/A MET 585.A N TYR 581.A O no hydrogen 3.160 N/A GLN 586.A N THR 582.A O no hydrogen 3.246 N/A ILE 587.A N PRO 583.A O no hydrogen 3.266 N/A ARG 588.A N ILE 584.A O no hydrogen 3.134 N/A ARG 588.A NE SER 498.A O no hydrogen 3.040 N/A ARG 588.A NH2 SER 498.A O no hydrogen 3.048 N/A GLY 589.A N MET 585.A O no hydrogen 2.853 N/A LEU 590.A N GLN 586.A O no hydrogen 3.078 N/A ILE 591.A N ILE 587.A O no hydrogen 2.904 N/A GLY 592.A N ARG 588.A O no hydrogen 2.968 N/A TYR 596.A OH GLY 592.A O no hydrogen 3.044 N/A TYR 599.A N SER 498.A OG no hydrogen 2.840 N/A MET 600.A N ASP 598.A OD1 no hydrogen 3.110 N/A THR 602.A N TYR 599.A O no hydrogen 3.322 N/A THR 602.A OG1 TYR 599.A O no hydrogen 2.471 N/A LEU 603.A N MET 600.A O no hydrogen 2.950 N/A