Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8a7h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 7.A N ASN 3.A O no hydrogen 3.055 N/A GLN 8.A N ALA 4.A O no hydrogen 2.935 N/A LEU 9.A N LYS 5.A O no hydrogen 2.937 N/A MET 10.A N LEU 6.A O no hydrogen 2.888 N/A VAL 11.A N LEU 7.A O no hydrogen 2.897 N/A GLU 12.A N GLN 8.A O no hydrogen 2.888 N/A HIS 13.A N LEU 9.A O no hydrogen 2.950 N/A HIS 13.A ND1 LEU 9.A O no hydrogen 3.155 N/A SER 14.A N VAL 11.A O no hydrogen 3.405 N/A ASP 16.A N SER 14.A OG no hydrogen 3.222 N/A GLY 17.A N GLN 116.A O no hydrogen 2.952 N/A ILE 18.A N ASN 34.A OD1 no hydrogen 3.004 N/A VAL 19.A N GLY 114.A O no hydrogen 2.941 N/A VAL 20.A N TYR 32.A O no hydrogen 2.868 N/A ALA 21.A N TYR 112.A O no hydrogen 2.893 N/A GLU 22.A N ILE 29.A O no hydrogen 2.728 N/A GLN 23.A N THR 110.A O no hydrogen 2.902 N/A GLU 24.A N GLU 27.A O no hydrogen 2.892 N/A GLU 27.A N GLU 24.A O no hydrogen 2.862 N/A SER 28.A N ASP 52.A OD2 no hydrogen 2.524 N/A ILE 29.A N GLU 22.A O no hydrogen 2.818 N/A LEU 30.A N GLN 51.A O no hydrogen 2.728 N/A ILE 31.A N VAL 20.A O no hydrogen 2.805 N/A TYR 32.A N VAL 20.A O no hydrogen 2.974 N/A TYR 32.A OH GLU 12.A OE1 no hydrogen 2.653 N/A ASN 34.A ND2 VAL 11.A O no hydrogen 3.697 N/A ASN 34.A ND2 ASP 16.A O no hydrogen 2.962 N/A PHE 37.A N ASN 34.A OD1 no hydrogen 3.033 N/A GLU 38.A N ASN 34.A O no hydrogen 3.201 N/A ARG 39.A N PRO 35.A O no hydrogen 2.910 N/A LEU 40.A N ALA 36.A O no hydrogen 2.909 N/A THR 41.A N PHE 37.A O no hydrogen 2.874 N/A GLY 42.A N GLU 38.A O no hydrogen 2.723 N/A ILE 48.A N ALA 45.A O no hydrogen 3.118 N/A LEU 49.A N ALA 45.A O no hydrogen 3.130 N/A TYR 50.A N LEU 30.A O no hydrogen 2.625 N/A CYS 53.A SG CYS 53.A O no hydrogen 2.362 N/A ARG 54.A N ASP 52.A OD1 no hydrogen 3.345 N/A ARG 54.A NH2 GLU 27.A OE1 no hydrogen 3.497 N/A LEU 56.A N CYS 53.A O no hydrogen 2.823 N/A GLN 57.A N ARG 54.A O no hydrogen 3.010 N/A GLY 58.A N PHE 55.A O no hydrogen 3.069 N/A ASP 60.A N GLN 57.A O no hydrogen 3.176 N/A HIS 61.A NE2 GLY 58.A O no hydrogen 2.547 N/A ARG 66.A N GLN 63.A O no hydrogen 3.003 N/A ARG 66.A NE HIS 61.A O no hydrogen 3.308 N/A ILE 68.A N PRO 64.A O no hydrogen 2.947 N/A ILE 69.A N GLY 65.A O no hydrogen 2.907 N/A ARG 70.A N ARG 66.A O no hydrogen 2.906 N/A GLU 71.A N ALA 67.A O no hydrogen 2.953 N/A ALA 72.A N ILE 68.A O no hydrogen 2.903 N/A ILE 73.A N ILE 69.A O no hydrogen 2.827 N/A ARG 74.A N ARG 70.A O no hydrogen 2.887 N/A ARG 74.A NH1 GLU 71.A OE1 no hydrogen 2.681 N/A GLU 75.A N GLU 71.A O no hydrogen 2.895 N/A GLY 76.A N ALA 72.A O no hydrogen 2.813 N/A CYS 79.A N ILE 99.A O no hydrogen 2.934 N/A CYS 80.A SG GLU 96.A OE2 no hydrogen 3.211 N/A CYS 80.A SG LEU 97.A O no hydrogen 3.839 N/A GLN 81.A N LEU 97.A O no hydrogen 2.910 N/A LEU 83.A N ASN 95.A O no hydrogen 2.970 N/A ARG 84.A NE ASP 60.A OD2 no hydrogen 2.445 N/A ARG 84.A NE GLN 63.A OE1 no hydrogen 3.000 N/A ARG 84.A NH2 ASP 60.A OD2 no hydrogen 2.337 N/A ASN 85.A N PHE 93.A O no hydrogen 2.912 N/A ASN 85.A ND2 ARG 84.A O no hydrogen 2.687 N/A TYR 86.A N LEU 56.A O no hydrogen 3.171 N/A TYR 86.A OH ASP 60.A OD2 no hydrogen 2.846 N/A ARG 87.A N SER 91.A O no hydrogen 3.109 N/A ARG 87.A NE LEU 40.A O no hydrogen 2.690 N/A ARG 87.A NH1 SER 91.A OG no hydrogen 2.798 N/A GLY 90.A N ARG 87.A O no hydrogen 3.283 N/A SER 91.A N ASP 89.A OD1 no hydrogen 3.112 N/A SER 91.A OG ASP 89.A OD1 no hydrogen 2.733 N/A SER 91.A OG ASP 89.A OD2 no hydrogen 3.202 N/A PHE 93.A N ASN 85.A O no hydrogen 2.892 N/A ASN 95.A N LEU 83.A O no hydrogen 2.917 N/A GLU 96.A N ARG 117.A O no hydrogen 2.927 N/A LEU 97.A N GLN 81.A O no hydrogen 2.875 N/A SER 98.A N ILE 115.A O no hydrogen 2.859 N/A ILE 99.A N CYS 79.A O no hydrogen 2.867 N/A THR 100.A N ILE 113.A O no hydrogen 2.889 N/A VAL 102.A N TYR 111.A O no hydrogen 2.859 N/A ASN 104.A N LEU 109.A O no hydrogen 2.905 N/A ALA 106.A N ASN 104.A OD1 no hydrogen 3.050 N/A GLN 108.A N GLU 105.A O no hydrogen 3.184 N/A GLN 108.A NE2 GLU 105.A O no hydrogen 3.543 N/A LEU 109.A N ASN 104.A O no hydrogen 2.932 N/A THR 110.A OG1 GLN 23.A OE1 no hydrogen 3.567 N/A TYR 111.A N VAL 102.A O no hydrogen 2.865 N/A TYR 111.A OH ASP 107.A OD2 no hydrogen 2.900 N/A TYR 112.A N ALA 21.A O no hydrogen 2.852 N/A ILE 113.A N THR 100.A O no hydrogen 2.913 N/A GLY 114.A N VAL 19.A O no hydrogen 2.871 N/A ILE 115.A N SER 98.A O no hydrogen 2.873 N/A GLN 116.A N GLY 17.A O no hydrogen 2.862 N/A ARG 117.A N GLU 96.A O no hydrogen 2.943 N/A VAL 119.A N TRP 94.A O no hydrogen 3.191 N/A GLN 123.A N VAL 119.A O no hydrogen 3.128 N/A GLN 124.A N THR 120.A O no hydrogen 2.916 N/A THR 125.A N GLU 121.A O no hydrogen 2.957 N/A THR 125.A OG1 GLU 121.A O no hydrogen 2.895 N/A THR 125.A OG1 HIS 122.A O no hydrogen 2.677 N/A GLN 126.A N HIS 122.A O no hydrogen 2.934 N/A ALA 127.A N GLN 123.A O no hydrogen 2.901 N/A ARG 128.A N GLN 124.A O no hydrogen 2.936 N/A LEU 129.A N THR 125.A O no hydrogen 2.914 N/A GLN 130.A N GLN 126.A O no hydrogen 2.931 N/A GLU 131.A N ALA 127.A O no hydrogen 2.936 N/A LEU 132.A N ARG 128.A O no hydrogen 2.928 N/A GLN 133.A N LEU 129.A O no hydrogen 2.892 N/A SER 134.A N GLN 130.A O no hydrogen 2.947 N/A GLU 135.A N GLU 131.A O no hydrogen 3.022 N/A LEU 136.A N LEU 132.A O no hydrogen 2.861 N/A VAL 137.A N GLN 133.A O no hydrogen 2.933 N/A HIS 138.A N SER 134.A O no hydrogen 2.973 N/A VAL 139.A N GLU 135.A O no hydrogen 2.976 N/A SER 140.A N LEU 136.A O no hydrogen 2.929 N/A SER 140.A OG LEU 136.A O no hydrogen 2.732 N/A ARG 141.A N VAL 137.A O no hydrogen 2.945 N/A LEU 142.A N HIS 138.A O no hydrogen 2.980 N/A SER 143.A N VAL 139.A O no hydrogen 2.935 N/A SER 143.A OG VAL 139.A O no hydrogen 3.259 N/A ALA 144.A N SER 140.A O no hydrogen 2.901 N/A MET 145.A N ARG 141.A O no hydrogen 2.991 N/A GLY 146.A N LEU 142.A O no hydrogen 2.904 N/A GLU 147.A N SER 143.A O no hydrogen 2.949 N/A MET 148.A N ALA 144.A O no hydrogen 2.970 N/A ALA 149.A N MET 145.A O no hydrogen 2.920 N/A SER 150.A N GLY 146.A O no hydrogen 2.940 N/A ALA 151.A N GLU 147.A O no hydrogen 2.978 N/A LEU 152.A N MET 148.A O no hydrogen 2.936 N/A ALA 153.A N ALA 149.A O no hydrogen 2.834 N/A HIS 154.A N SER 150.A O no hydrogen 3.003 N/A GLU 155.A N ALA 151.A O no hydrogen 2.942 N/A LEU 156.A N LEU 152.A O no hydrogen 2.908 N/A ASN 157.A N ALA 153.A O no hydrogen 2.808 N/A GLN 158.A N HIS 154.A O no hydrogen 3.202 N/A LEU 160.A N LEU 156.A O no hydrogen 3.104 N/A ALA 161.A N ASN 157.A O no hydrogen 3.298 N/A ALA 162.A N GLN 158.A O no hydrogen 3.018 N/A ILE 163.A N PRO 159.A O no hydrogen 2.877 N/A SER 164.A N LEU 160.A O no hydrogen 2.945 N/A ASN 165.A N ALA 161.A O no hydrogen 2.917 N/A TYR 166.A N ALA 162.A O no hydrogen 2.916 N/A MET 167.A N ILE 163.A O no hydrogen 2.930 N/A LYS 168.A N SER 164.A O no hydrogen 2.947 N/A GLY 169.A N ASN 165.A O no hydrogen 2.872 N/A SER 170.A N TYR 166.A O no hydrogen 2.896 N/A SER 170.A OG TYR 166.A O no hydrogen 2.776 N/A ARG 171.A N MET 167.A O no hydrogen 2.941 N/A ARG 172.A N LYS 168.A O no hydrogen 2.910 N/A LEU 173.A N GLY 169.A O no hydrogen 2.897 N/A LEU 174.A N SER 170.A O no hydrogen 2.900 N/A ALA 175.A N ARG 171.A O no hydrogen 2.909 N/A SER 177.A OG THR 182.A OG1 no hydrogen 3.386 N/A ASP 179.A N SER 177.A OG no hydrogen 3.264 N/A THR 182.A N ASP 179.A O no hydrogen 3.241 N/A THR 182.A OG1 SER 177.A OG no hydrogen 3.386 N/A VAL 185.A N ASN 181.A O no hydrogen 3.094 N/A GLU 186.A N THR 182.A O no hydrogen 2.773 N/A SER 187.A N PRO 183.A O no hydrogen 2.742 N/A ALA 188.A N LYS 184.A O no hydrogen 2.889 N/A LEU 189.A N VAL 185.A O no hydrogen 2.992 N/A ASP 190.A N GLU 186.A O no hydrogen 3.127 N/A ARG 191.A N SER 187.A O no hydrogen 3.049 N/A ALA 192.A N ALA 188.A O no hydrogen 3.041 N/A ALA 193.A N LEU 189.A O no hydrogen 2.588 N/A GLU 194.A N ASP 190.A O no hydrogen 2.531 N/A GLN 195.A N ARG 191.A O no hydrogen 2.925 N/A ALA 196.A N ALA 192.A O no hydrogen 2.701 N/A LEU 197.A N ALA 193.A O no hydrogen 2.882 N/A ARG 198.A N GLU 194.A O no hydrogen 3.278 N/A ALA 199.A N GLN 195.A O no hydrogen 3.113 N/A GLY 200.A N ALA 196.A O no hydrogen 3.367 N/A GLN 201.A N LEU 197.A O no hydrogen 3.204 N/A ILE 202.A N ARG 198.A O no hydrogen 2.755 N/A ILE 203.A N ALA 199.A O no hydrogen 2.946 N/A ARG 204.A N GLY 200.A O no hydrogen 3.100 N/A ARG 205.A N GLN 201.A O no hydrogen 2.711 N/A LEU 206.A N ILE 202.A O no hydrogen 2.872 N/A ARG 207.A N ILE 203.A O no hydrogen 2.626 N/A ASP 208.A N ARG 204.A O no hydrogen 2.590 N/A PHE 209.A N ARG 205.A O no hydrogen 2.814 N/A PHE 209.A N LEU 206.A O no hydrogen 2.952 N/A VAL 210.A N LEU 206.A O no hydrogen 3.128 N/A VAL 210.A N ARG 207.A O no hydrogen 2.960 N/A ALA 211.A N ARG 207.A O no hydrogen 3.062 N/A ARG 218.A N ALA 257.A O no hydrogen 2.922 N/A GLU 220.A N VAL 255.A O no hydrogen 2.887 N/A LEU 222.A N ASP 253.A O no hydrogen 2.636 N/A LEU 225.A N SER 221.A O no hydrogen 3.358 N/A ILE 226.A N LEU 222.A O no hydrogen 2.884 N/A GLU 227.A N SER 223.A O no hydrogen 2.999 N/A GLU 228.A N LYS 224.A O no hydrogen 2.937 N/A ALA 229.A N LEU 225.A O no hydrogen 2.869 N/A GLY 230.A N ILE 226.A O no hydrogen 2.892 N/A ALA 231.A N GLU 227.A O no hydrogen 2.907 N/A LEU 232.A N GLU 228.A O no hydrogen 3.001 N/A GLY 233.A N ALA 229.A O no hydrogen 2.824 N/A LEU 234.A N GLY 230.A O no hydrogen 3.091 N/A ALA 237.A N LEU 234.A O no hydrogen 3.288 N/A GLN 240.A N GLY 236.A O no hydrogen 2.665 N/A VAL 242.A N ALA 237.A O no hydrogen 2.901 N/A GLN 243.A N ARG 283.A O no hydrogen 3.078 N/A ARG 245.A N LEU 285.A O no hydrogen 3.009 N/A SER 247.A N VAL 287.A O no hydrogen 2.869 N/A ASP 249.A N ASN 289.A OD1 no hydrogen 2.980 N/A GLY 251.A N ASP 249.A OD1 no hydrogen 3.282 N/A ALA 252.A N ASP 249.A O no hydrogen 3.205 N/A VAL 255.A N GLU 220.A O no hydrogen 2.967 N/A ALA 257.A N ARG 218.A O no hydrogen 2.864 N/A ILE 262.A N ASP 258.A O no hydrogen 3.097 N/A GLN 263.A N ARG 259.A O no hydrogen 2.809 N/A GLN 264.A N VAL 260.A O no hydrogen 2.911 N/A GLN 264.A NE2 SER 143.A OG no hydrogen 3.096 N/A VAL 265.A N GLN 261.A O no hydrogen 2.967 N/A LEU 266.A N ILE 262.A O no hydrogen 2.905 N/A VAL 267.A N GLN 263.A O no hydrogen 2.784 N/A ASN 268.A N GLN 264.A O no hydrogen 2.931 N/A ASN 268.A ND2 GLN 264.A O no hydrogen 3.513 N/A LEU 269.A N VAL 265.A O no hydrogen 2.990 N/A PHE 270.A N LEU 266.A O no hydrogen 2.824 N/A ARG 271.A N VAL 267.A O no hydrogen 2.887 N/A ASN 272.A N ASN 268.A O no hydrogen 2.983 N/A ALA 273.A N LEU 269.A O no hydrogen 2.917 N/A LEU 274.A N PHE 270.A O no hydrogen 2.897 N/A GLU 275.A N ARG 271.A O no hydrogen 2.924 N/A ALA 276.A N ASN 272.A O no hydrogen 2.926 N/A MET 277.A N ALA 273.A O no hydrogen 2.925 N/A SER 280.A OG ARG 282.A O no hydrogen 2.297 N/A SER 280.A OG THR 304.A O no hydrogen 2.777 N/A ARG 283.A NE SER 280.A O no hydrogen 3.371 N/A ARG 283.A NH1 GLN 240.A O no hydrogen 3.172 N/A LEU 285.A N GLN 243.A O no hydrogen 2.797 N/A VAL 286.A N SER 302.A O no hydrogen 2.974 N/A VAL 287.A N ARG 245.A O no hydrogen 2.843 N/A THR 288.A N GLU 300.A O no hydrogen 2.930 N/A ASN 289.A N SER 247.A O no hydrogen 3.024 N/A THR 290.A N GLU 298.A O no hydrogen 2.914 N/A THR 290.A OG1 GLU 298.A O no hydrogen 3.538 N/A ALA 292.A N MET 296.A O no hydrogen 2.971 N/A MET 296.A N ALA 293.A O no hydrogen 2.947 N/A ILE 297.A N LEU 362.A O no hydrogen 2.982 N/A GLU 298.A N THR 290.A O no hydrogen 2.864 N/A VAL 299.A N PHE 360.A O no hydrogen 2.878 N/A GLU 300.A N THR 288.A O no hydrogen 2.865 N/A VAL 301.A N PHE 358.A O no hydrogen 2.884 N/A SER 302.A N VAL 286.A O no hydrogen 2.883 N/A ASP 303.A N ALA 356.A O no hydrogen 2.808 N/A THR 304.A OG1 ARG 282.A O no hydrogen 2.343 N/A GLY 305.A N ASP 303.A OD1 no hydrogen 3.109 N/A SER 306.A N ALA 276.A O no hydrogen 3.295 N/A SER 306.A OG ALA 276.A O no hydrogen 3.426 N/A VAL 312.A N GLN 309.A O no hydrogen 2.987 N/A ASN 315.A N VAL 312.A O no hydrogen 2.792 N/A LEU 316.A N ILE 313.A O no hydrogen 3.320 N/A GLN 318.A N ASN 315.A O no hydrogen 3.372 N/A THR 319.A OG1 GLU 147.A OE2 no hydrogen 2.393 N/A THR 319.A OG1 SER 333.A OG no hydrogen 2.912 N/A PHE 320.A N GLY 329.A O no hydrogen 3.019 N/A PHE 321.A N GLN 318.A O no hydrogen 3.457 N/A LYS 324.A NZ ASN 272.A OD1 no hydrogen 2.318 N/A GLY 327.A N LYS 324.A O no hydrogen 3.235 N/A SER 333.A OG GLU 147.A OE2 no hydrogen 3.126 N/A SER 333.A OG THR 319.A OG1 no hydrogen 2.912 N/A ILE 334.A N VAL 330.A O no hydrogen 2.911 N/A SER 335.A N GLY 331.A O no hydrogen 2.895 N/A SER 335.A OG GLY 331.A O no hydrogen 3.083 N/A ARG 336.A N LEU 332.A O no hydrogen 2.880 N/A SER 337.A N SER 333.A O no hydrogen 2.971 N/A SER 337.A OG SER 333.A O no hydrogen 3.270 N/A SER 337.A OG ILE 334.A O no hydrogen 2.689 N/A ILE 338.A N ILE 334.A O no hydrogen 2.907 N/A ILE 339.A N SER 335.A O no hydrogen 2.914 N/A GLU 340.A N ARG 336.A O no hydrogen 2.901 N/A ALA 341.A N SER 337.A O no hydrogen 2.900 N/A HIS 342.A N ILE 338.A O no hydrogen 3.061 N/A HIS 342.A N ILE 339.A O no hydrogen 3.133 N/A HIS 342.A ND1 ILE 338.A O no hydrogen 2.563 N/A GLY 343.A N GLU 340.A O no hydrogen 3.015 N/A GLY 344.A N ILE 339.A O no hydrogen 2.972 N/A ARG 345.A N THR 361.A OG1 no hydrogen 2.872 N/A TRP 347.A N ARG 359.A O no hydrogen 3.033 N/A GLU 349.A N THR 357.A O no hydrogen 3.201 N/A SER 350.A OG ASN 351.A O no hydrogen 3.306 N/A GLY 354.A N ASN 351.A O no hydrogen 3.169 N/A ALA 356.A N ASP 303.A O no hydrogen 3.179 N/A THR 357.A N GLU 349.A O no hydrogen 3.151 N/A THR 357.A OG1 GLU 349.A O no hydrogen 3.386 N/A THR 357.A OG1 GLU 349.A OE2 no hydrogen 3.568 N/A PHE 358.A N VAL 301.A O no hydrogen 2.908 N/A ARG 359.A N TRP 347.A O no hydrogen 3.002 N/A ARG 359.A NE GLU 349.A OE2 no hydrogen 3.484 N/A ARG 359.A NH1 GLU 298.A OE2 no hydrogen 2.599 N/A ARG 359.A NH2 GLU 349.A OE2 no hydrogen 3.501 N/A PHE 360.A N VAL 299.A O no hydrogen 2.999 N/A THR 361.A OG1 ARG 345.A O no hydrogen 3.447 N/A LEU 362.A N ILE 297.A O no hydrogen 2.899 N/A