Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8axv_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PRO 1.A N GLU 24.A OE1 no hydrogen 2.719 N/A VAL 2.A N GLU 24.A O no hydrogen 2.403 N/A VAL 4.A N GLU 26.A O no hydrogen 2.908 N/A SER 10.A N ASP 7.A O no hydrogen 3.126 N/A LEU 13.A N SER 10.A O no hydrogen 3.236 N/A ALA 15.A N ALA 11.A O no hydrogen 2.945 N/A LEU 16.A N PHE 12.A O no hydrogen 2.838 N/A GLN 17.A N LEU 13.A O no hydrogen 2.930 N/A ARG 18.A N LYS 14.A O no hydrogen 2.927 N/A ARG 18.A NH2 ALA 299.A O no hydrogen 2.874 N/A ALA 19.A N ALA 15.A O no hydrogen 2.894 N/A TYR 20.A N LEU 16.A O no hydrogen 2.748 N/A TYR 20.A N GLN 17.A O no hydrogen 3.299 N/A PHE 23.A N TYR 20.A O no hydrogen 3.304 N/A GLU 24.A N GLU 24.A OE1 no hydrogen 2.942 N/A GLU 26.A N VAL 2.A O no hydrogen 2.890 N/A GLN 29.A NE2 PRO 32.A O no hydrogen 3.668 N/A ARG 39.A N HIS 35.A O no hydrogen 3.164 N/A ALA 40.A N ALA 36.A O no hydrogen 2.869 N/A PHE 41.A N ASN 37.A O no hydrogen 2.938 N/A SER 42.A N ALA 38.A O no hydrogen 2.906 N/A SER 42.A OG ALA 38.A O no hydrogen 2.493 N/A HIS 43.A N ARG 39.A O no hydrogen 2.885 N/A LEU 44.A N ALA 40.A O no hydrogen 2.905 N/A ALA 45.A N PHE 41.A O no hydrogen 2.903 N/A ILE 46.A N SER 42.A O no hydrogen 2.884 N/A LYS 47.A N HIS 43.A O no hydrogen 2.902 N/A LEU 48.A N LEU 44.A O no hydrogen 2.905 N/A ILE 49.A N ALA 45.A O no hydrogen 2.902 N/A GLU 50.A N ILE 46.A O no hydrogen 2.888 N/A GLN 51.A N LYS 47.A O no hydrogen 2.913 N/A GLU 52.A N LEU 48.A O no hydrogen 3.201 N/A GLU 52.A N ILE 49.A O no hydrogen 3.140 N/A ASP 56.A N ASP 54.A OD2 no hydrogen 3.410 N/A SER 57.A N ASP 54.A O no hydrogen 3.127 N/A SER 57.A OG ASP 54.A O no hydrogen 2.948 N/A ILE 59.A N LYS 75.A O no hydrogen 3.095 N/A LEU 60.A N VAL 145.A O no hydrogen 3.241 N/A ASP 61.A N HIS 77.A O no hydrogen 3.258 N/A SER 64.A N ILE 62.A O no hydrogen 2.673 N/A ARG 68.A N ALA 65.A O no hydrogen 2.742 N/A ARG 69.A NH2 ASP 61.A OD1 no hydrogen 2.841 N/A MET 70.A N ARG 68.A O no hydrogen 2.752 N/A ASP 73.A N ASP 73.A OD1 no hydrogen 2.426 N/A ARG 74.A NH2 GLU 50.A O no hydrogen 3.096 N/A HIS 77.A N ILE 59.A O no hydrogen 3.134 N/A HIS 77.A ND1 PRO 129.A O no hydrogen 2.557 N/A CYS 80.A N CYS 132.A O no hydrogen 3.421 N/A CYS 80.A SG SER 64.A OG no hydrogen 2.892 N/A ARG 90.A N GLU 86.A O no hydrogen 3.267 N/A LEU 91.A N ASP 87.A O no hydrogen 2.917 N/A ALA 92.A N PRO 88.A O no hydrogen 2.616 N/A ASN 93.A N GLU 89.A O no hydrogen 3.039 N/A TYR 94.A N ARG 90.A O no hydrogen 2.767 N/A ALA 95.A N LEU 91.A O no hydrogen 2.815 N/A ARG 96.A N ALA 92.A O no hydrogen 2.861 N/A LYS 97.A N ASN 93.A O no hydrogen 2.488 N/A LEU 98.A N TYR 94.A O no hydrogen 2.768 N/A ALA 99.A N ALA 95.A O no hydrogen 2.838 N/A SER 100.A N ARG 96.A O no hydrogen 2.655 N/A SER 100.A OG LYS 97.A O no hydrogen 2.264 N/A ALA 101.A N LYS 97.A O no hydrogen 2.763 N/A ALA 102.A N ALA 99.A O no hydrogen 2.919 N/A LYS 113.A N ASN 109.A O no hydrogen 3.227 N/A ILE 114.A N ILE 110.A O no hydrogen 2.929 N/A GLY 115.A N SER 111.A O no hydrogen 2.895 N/A ASP 116.A N GLY 112.A O no hydrogen 2.891 N/A LEU 117.A N LYS 113.A O no hydrogen 2.926 N/A GLN 118.A N ILE 114.A O no hydrogen 2.897 N/A ALA 119.A N GLY 115.A O no hydrogen 2.899 N/A VAL 120.A N ASP 116.A O no hydrogen 2.914 N/A MET 121.A N LEU 117.A O no hydrogen 2.886 N/A ALA 122.A N GLN 118.A O no hydrogen 2.910 N/A VAL 123.A N ALA 119.A O no hydrogen 3.041 N/A THR 126.A N VAL 123.A O no hydrogen 3.264 N/A THR 130.A N ASP 116.A OD2 no hydrogen 3.230 N/A THR 130.A OG1 ASP 116.A OD2 no hydrogen 3.185 N/A PHE 131.A N THR 128.A O no hydrogen 3.454 N/A CYS 132.A SG THR 126.A O no hydrogen 3.889 N/A CYS 132.A SG HIS 134.A ND1 no hydrogen 3.250 N/A SER 138.A N THR 135.A OG1 no hydrogen 3.345 N/A CYS 139.A SG HIS 77.A NE2 no hydrogen 3.407 N/A ASP 144.A N THR 58.A O no hydrogen 2.708 N/A ALA 146.A N LEU 170.A O no hydrogen 2.799 N/A ILE 147.A N LEU 60.A O no hydrogen 3.296 N/A TYR 148.A N TYR 172.A O no hydrogen 2.668 N/A ASP 150.A N VAL 174.A O no hydrogen 2.997 N/A TYR 152.A OH ASP 150.A OD1 no hydrogen 2.651 N/A HIS 155.A ND1 THR 158.A OG1 no hydrogen 3.280 N/A ALA 156.A N SER 247.A OG no hydrogen 2.634 N/A THR 158.A OG1 HIS 155.A ND1 no hydrogen 3.280 N/A SER 159.A N HIS 155.A O no hydrogen 3.093 N/A SER 159.A OG TYR 148.A OH no hydrogen 3.065 N/A SER 159.A OG HIS 155.A O no hydrogen 3.231 N/A SER 159.A OG ALA 156.A O no hydrogen 3.012 N/A LEU 160.A N ALA 156.A O no hydrogen 2.925 N/A TYR 161.A N PRO 157.A O no hydrogen 2.875 N/A HIS 162.A N THR 158.A O no hydrogen 2.919 N/A HIS 162.A ND1 THR 158.A O no hydrogen 3.079 N/A GLN 163.A N SER 159.A O no hydrogen 2.919 N/A GLN 163.A N LEU 160.A O no hydrogen 3.255 N/A ALA 164.A N LEU 160.A O no hydrogen 2.858 N/A ILE 165.A N TYR 161.A O no hydrogen 2.957 N/A LYS 166.A NZ ASP 136.A O no hydrogen 3.415 N/A GLY 167.A N ALA 164.A O no hydrogen 2.622 N/A ARG 169.A N ASP 144.A O no hydrogen 3.079 N/A ARG 169.A NE MET 282.A O no hydrogen 2.974 N/A ALA 171.A N ILE 280.A O no hydrogen 2.901 N/A TYR 172.A N ALA 146.A O no hydrogen 2.928 N/A TRP 173.A N LYS 278.A O no hydrogen 2.901 N/A TRP 173.A NE1 VAL 151.A O no hydrogen 3.084 N/A GLY 175.A N VAL 276.A O no hydrogen 2.956 N/A ASP 177.A N GLY 274.A O no hydrogen 2.439 N/A THR 179.A N ASP 177.A OD1 no hydrogen 3.325 N/A THR 179.A OG1 ASP 177.A OD1 no hydrogen 2.748 N/A THR 179.A OG1 ASP 177.A OD2 no hydrogen 2.532 N/A PHE 181.A N THR 178.A O no hydrogen 3.204 N/A MET 182.A N THR 178.A O no hydrogen 3.169 N/A TYR 183.A N THR 179.A O no hydrogen 3.042 N/A TYR 183.A OH SER 408.A OG no hydrogen 2.560 N/A ASN 184.A N PHE 181.A O no hydrogen 3.368 N/A ALA 185.A N PRO 180.A O no hydrogen 3.105 N/A MET 186.A N SER 319.A O no hydrogen 2.816 N/A ALA 187.A N SER 319.A O no hydrogen 3.125 N/A GLY 188.A N TRP 197.A O no hydrogen 2.923 N/A ALA 189.A N CYS 321.A O no hydrogen 3.164 N/A TYR 190.A N THR 195.A O no hydrogen 2.884 N/A TYR 190.A OH ASP 177.A O no hydrogen 3.054 N/A SER 192.A N TYR 190.A O no hydrogen 2.438 N/A SER 192.A OG PRO 191.A O no hydrogen 3.226 N/A TYR 193.A N TYR 190.A O no hydrogen 2.878 N/A TYR 193.A OH CYS 272.A O no hydrogen 2.523 N/A THR 195.A OG1 TYR 193.A O no hydrogen 3.020 N/A ASN 196.A N SER 232.A O no hydrogen 2.921 N/A ASN 196.A ND2 TYR 361.A OH no hydrogen 3.194 N/A TRP 197.A N GLY 188.A O no hydrogen 2.888 N/A ALA 198.A N LEU 230.A O no hydrogen 2.940 N/A ASP 199.A N MET 186.A O no hydrogen 2.890 N/A GLU 200.A N ARG 228.A O no hydrogen 3.440 N/A GLN 201.A NE2 GLU 224.A O no hydrogen 2.632 N/A VAL 202.A N ASP 199.A O no hydrogen 2.765 N/A ALA 205.A N VAL 202.A O no hydrogen 3.209 N/A LYS 206.A N ASP 309.A OD2 no hydrogen 3.254 N/A LYS 206.A NZ ASN 207.A OD1 no hydrogen 3.067 N/A ASN 207.A N ASP 309.A OD2 no hydrogen 3.181 N/A CYS 211.A SG ALA 205.A O no hydrogen 2.910 N/A CYS 211.A SG ILE 208.A O no hydrogen 2.971 N/A SER 212.A N LEU 203.A O no hydrogen 3.094 N/A SER 212.A OG CYS 211.A O no hydrogen 2.806 N/A THR 216.A N ASP 214.A O no hydrogen 2.777 N/A CYS 226.A N ASP 199.A OD2 no hydrogen 2.795 N/A CYS 226.A SG GLN 201.A OE1 no hydrogen 2.865 N/A CYS 226.A SG GLU 224.A O no hydrogen 3.662 N/A VAL 229.A N GLU 240.A O no hydrogen 2.928 N/A LEU 230.A N ALA 198.A O no hydrogen 2.891 N/A PHE 231.A N TYR 238.A O no hydrogen 2.895 N/A SER 232.A N ASN 196.A O no hydrogen 2.854 N/A VAL 233.A N THR 236.A O no hydrogen 2.888 N/A GLY 234.A N SER 194.A O no hydrogen 2.545 N/A THR 236.A N VAL 233.A O no hydrogen 2.921 N/A TYR 238.A N PHE 231.A O no hydrogen 2.869 N/A GLU 240.A N VAL 229.A O no hydrogen 2.888 N/A SER 241.A OG ASP 227.A OD1 no hydrogen 1.951 N/A ARG 242.A N ASP 227.A O no hydrogen 2.557 N/A ARG 242.A NE CYS 226.A O no hydrogen 3.096 N/A ARG 242.A NH1 ALA 185.A O no hydrogen 3.122 N/A ARG 242.A NH2 ALA 185.A O no hydrogen 2.569 N/A LEU 245.A N SER 241.A O no hydrogen 2.875 N/A LEU 245.A N ARG 242.A O no hydrogen 2.992 N/A LYS 246.A N ARG 242.A O no hydrogen 2.664 N/A LYS 246.A NZ PHE 181.A O no hydrogen 3.278 N/A HIS 249.A NE2 THR 296.A OG1 no hydrogen 3.151 N/A SER 252.A N TYR 293.A O no hydrogen 2.986 N/A PHE 254.A N CYS 264.A O no hydrogen 2.897 N/A HIS 255.A N ALA 414.A O no hydrogen 2.503 N/A LEU 256.A N PHE 262.A O no hydrogen 2.898 N/A LYS 257.A N PHE 416.A O no hydrogen 2.645 N/A PHE 262.A N LEU 256.A O no hydrogen 2.901 N/A THR 263.A N SER 283.A O no hydrogen 2.670 N/A CYS 264.A N PHE 254.A O no hydrogen 2.897 N/A CYS 264.A SG PHE 254.A O no hydrogen 3.826 N/A ARG 265.A N THR 281.A O no hydrogen 3.149 N/A CYS 266.A N SER 252.A O no hydrogen 3.108 N/A CYS 266.A SG ARG 279.A O no hydrogen 4.031 N/A ASP 267.A N ARG 279.A O no hydrogen 2.897 N/A VAL 269.A N VAL 277.A O no hydrogen 3.052 N/A CYS 272.A N TYR 275.A O no hydrogen 2.888 N/A TYR 275.A N CYS 272.A O no hydrogen 2.915 N/A TYR 275.A OH ASP 150.A OD1 no hydrogen 2.640 N/A VAL 276.A N GLY 175.A O no hydrogen 2.869 N/A VAL 277.A N VAL 270.A O no hydrogen 2.909 N/A LYS 278.A N TRP 173.A O no hydrogen 2.891 N/A LYS 278.A NZ TRP 248.A O no hydrogen 2.667 N/A ARG 279.A N ASP 267.A O no hydrogen 3.265 N/A ILE 280.A N ALA 171.A O no hydrogen 2.895 N/A THR 281.A N ARG 265.A O no hydrogen 2.861 N/A THR 281.A OG1 ARG 265.A O no hydrogen 3.371 N/A MET 282.A N ARG 169.A O no hydrogen 2.735 N/A SER 283.A N THR 263.A O no hydrogen 3.257 N/A GLY 285.A N SER 261.A O no hydrogen 2.704 N/A LYS 289.A NZ THR 290.A O no hydrogen 3.405 N/A THR 290.A OG1 GLU 415.A OE2 no hydrogen 2.739 N/A ALA 294.A N GLN 410.A O no hydrogen 2.869 N/A THR 296.A N SER 408.A O no hydrogen 2.908 N/A HIS 298.A N THR 406.A O no hydrogen 2.915 N/A HIS 298.A NE2 SER 408.A OG no hydrogen 2.292 N/A PHE 302.A N LYS 402.A O no hydrogen 2.919 N/A LEU 303.A N THR 322.A O no hydrogen 2.920 N/A MET 304.A N VAL 400.A O no hydrogen 2.911 N/A CYS 305.A N VAL 320.A O no hydrogen 2.941 N/A CYS 305.A SG.A HIS 398.A O no hydrogen 3.846 N/A CYS 305.A SG.B VAL 365.A O no hydrogen 4.044 N/A LYS 306.A N HIS 398.A O no hydrogen 3.464 N/A THR 307.A N PHE 318.A O no hydrogen 2.869 N/A THR 308.A OG1 VAL 316.A O no hydrogen 2.981 N/A ASP 309.A N VAL 316.A O no hydrogen 2.878 N/A VAL 311.A N GLU 314.A O no hydrogen 2.889 N/A GLU 314.A N VAL 311.A O no hydrogen 2.912 N/A VAL 316.A N ASP 309.A O no hydrogen 2.909 N/A PHE 318.A N THR 307.A O no hydrogen 2.939 N/A VAL 320.A N CYS 305.A O no hydrogen 2.889 N/A CYS 321.A N ALA 187.A O no hydrogen 3.039 N/A CYS 321.A SG ALA 187.A O no hydrogen 3.843 N/A THR 322.A N LEU 303.A O no hydrogen 2.863 N/A TYR 323.A OH ASP 177.A OD2 no hydrogen 2.800 N/A CYS 329.A N PRO 325.A O no hydrogen 3.376 N/A CYS 329.A SG PRO 325.A O no hydrogen 3.676 N/A CYS 329.A SG TYR 401.A OH no hydrogen 2.686 N/A ASP 330.A N ALA 326.A O no hydrogen 2.907 N/A GLN 331.A N THR 327.A O no hydrogen 2.914 N/A MET 332.A N ILE 328.A O no hydrogen 2.890 N/A MET 332.A N CYS 329.A O no hydrogen 3.183 N/A THR 333.A N ASP 330.A O no hydrogen 3.225 N/A THR 333.A OG1 CYS 329.A O no hydrogen 2.982 N/A THR 333.A OG1 ASP 330.A O no hydrogen 2.359 N/A LEU 336.A N MET 332.A O no hydrogen 2.856 N/A ALA 337.A N THR 333.A O no hydrogen 2.954 N/A THR 338.A N ILE 335.A O no hydrogen 2.750 N/A THR 338.A OG1 ILE 335.A O no hydrogen 2.662 N/A THR 341.A OG1 ASP 344.A OD2 no hydrogen 2.324 N/A ASP 344.A N THR 341.A OG1 no hydrogen 2.801 N/A ALA 345.A N THR 341.A O no hydrogen 2.746 N/A GLN 346.A N PRO 342.A O no hydrogen 2.863 N/A LYS 347.A N GLU 343.A O no hydrogen 2.921 N/A LEU 348.A N ASP 344.A O no hydrogen 2.924 N/A LEU 349.A N ALA 345.A O no hydrogen 2.856 N/A VAL 350.A N GLN 346.A O no hydrogen 2.883 N/A GLY 351.A N LYS 347.A O no hydrogen 2.931 N/A LEU 352.A N LEU 348.A O no hydrogen 2.865 N/A ASN 353.A N LEU 349.A O no hydrogen 2.889 N/A ASN 353.A ND2 MET 358.A O no hydrogen 2.748 N/A GLN 354.A N VAL 350.A O no hydrogen 3.145 N/A THR 357.A N ASN 353.A OD1 no hydrogen 2.330 N/A MET 358.A N ASN 353.A OD1 no hydrogen 3.375 N/A LYS 359.A NZ SER 194.A OG no hydrogen 3.305 N/A MET 362.A N LYS 359.A O MET 362.A H 3.260 2.429 ILE 363.A N ASN 360.A O no hydrogen 3.207 N/A VAL 365.A N MET 362.A O no hydrogen 2.880 N/A VAL 366.A N MET 362.A O no hydrogen 2.801 N/A ALA 367.A N ILE 363.A O no hydrogen 2.886 N/A ALA 369.A N VAL 365.A O no hydrogen 2.919 N/A PHE 370.A N VAL 366.A O no hydrogen 2.888 N/A SER 371.A N ALA 367.A O no hydrogen 2.903 N/A SER 371.A OG VAL 340.A O no hydrogen 2.982 N/A SER 371.A OG ALA 367.A O no hydrogen 2.755 N/A LYS 372.A N GLN 368.A O no hydrogen 2.908 N/A TRP 373.A N ALA 369.A O no hydrogen 2.901 N/A ALA 374.A N PHE 370.A O no hydrogen 2.899 N/A LYS 375.A N SER 371.A O no hydrogen 2.918 N/A GLU 376.A N LYS 372.A O no hydrogen 2.917 N/A CYS 377.A N TRP 373.A O no hydrogen 2.879 N/A CYS 377.A SG TRP 373.A O no hydrogen 3.480 N/A ARG 378.A N ALA 374.A O no hydrogen 2.927 N/A ARG 378.A NH1 ALA 337.A O no hydrogen 2.421 N/A ARG 378.A NH2 ALA 337.A O no hydrogen 2.571 N/A LYS 379.A N LYS 375.A O no hydrogen 2.899 N/A ASP 380.A N GLU 376.A O no hydrogen 2.878 N/A MET 381.A N CYS 377.A O no hydrogen 2.908 N/A ASP 383.A N ASP 380.A O no hydrogen 3.249 N/A LEU 386.A N GLU 391.A OE2 no hydrogen 2.843 N/A LYS 394.A N PHE 392.A O no hydrogen 2.795 N/A HIS 398.A N GLU 376.A OE2 no hydrogen 2.643 N/A VAL 400.A N MET 304.A O no hydrogen 2.882 N/A LYS 402.A N PHE 302.A O no hydrogen 2.897 N/A LYS 402.A NZ GLN 407.A O no hydrogen 3.268 N/A ASP 405.A N HIS 298.A O no hydrogen 2.772 N/A THR 406.A N ARG 403.A O no hydrogen 3.257 N/A THR 406.A OG1 ARG 403.A O no hydrogen 2.643 N/A SER 408.A N THR 296.A O no hydrogen 2.878 N/A SER 408.A OG TYR 183.A OH no hydrogen 2.560 N/A SER 408.A OG HIS 298.A NE2 no hydrogen 2.292 N/A GLN 410.A N ALA 294.A O no hydrogen 2.961 N/A VAL 412.A N GLY 292.A O no hydrogen 3.174 N/A PHE 416.A N HIS 255.A O no hydrogen 2.778 N/A LEU 424.A N SER 421.A OG no hydrogen 3.163 N/A ARG 425.A N SER 421.A O no hydrogen 2.794 N/A THR 426.A N ILE 422.A O no hydrogen 2.911 N/A THR 426.A OG1 ILE 422.A O no hydrogen 2.884 N/A ARG 427.A N PRO 423.A O no hydrogen 2.906 N/A ILE 428.A N LEU 424.A O no hydrogen 2.903 N/A LYS 429.A NZ ARG 425.A O no hydrogen 3.397 N/A