Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8bzi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 SER 75.A OG no hydrogen 2.887 N/A ASN 2.A N SER 75.A O no hydrogen 2.777 N/A LYS 4.A N ASN 2.A OD1 no hydrogen 3.084 N/A ALA 5.A N ASN 2.A OD1 no hydrogen 2.875 N/A GLU 8.A N ASP 6.A OD1 no hydrogen 2.890 N/A GLU 9.A N ASP 6.A O no hydrogen 2.960 N/A LEU 10.A N ASP 6.A O no hydrogen 3.158 N/A PHE 11.A N PRO 7.A O no hydrogen 2.918 N/A THR 12.A N ILE 29.A O no hydrogen 2.871 N/A THR 12.A OG1 ASN 31.A OD1 no hydrogen 2.647 N/A LEU 14.A N LYS 27.A O no hydrogen 2.726 N/A GLU 15.A N GLU 15.A OE1 no hydrogen 2.798 N/A LYS 16.A NZ GLU 24.A OE1 no hydrogen 2.409 N/A ILE 17.A N VAL 25.A O no hydrogen 2.864 N/A GLY 18.A N VAL 25.A O no hydrogen 3.352 N/A GLY 20.A N GLY 23.A O no hydrogen 3.184 N/A VAL 25.A N GLY 18.A O no hydrogen 2.943 N/A PHE 26.A N ILE 39.A O no hydrogen 2.697 N/A LYS 27.A N GLU 15.A O no hydrogen 2.844 N/A LYS 27.A NZ GLU 15.A OE2 no hydrogen 2.925 N/A GLY 28.A N VAL 37.A O no hydrogen 2.846 N/A ILE 29.A N THR 12.A O no hydrogen 2.853 N/A ASP 30.A N LYS 35.A O no hydrogen 2.838 N/A ASN 31.A N LEU 10.A O no hydrogen 2.938 N/A ASN 31.A ND2 GLU 9.A O no hydrogen 2.948 N/A ARG 32.A N ASP 30.A OD1 no hydrogen 2.803 N/A THR 33.A N ASP 30.A OD1 no hydrogen 3.096 N/A GLN 34.A N ASP 30.A O no hydrogen 2.668 N/A LYS 35.A N THR 33.A OG1 no hydrogen 3.152 N/A VAL 37.A N GLY 28.A O no hydrogen 2.775 N/A ALA 38.A N MET 86.A O no hydrogen 2.826 N/A ILE 39.A N PHE 26.A O no hydrogen 2.753 N/A LYS 40.A N ILE 84.A O no hydrogen 2.939 N/A LYS 40.A NZ SER 21.A O no hydrogen 2.983 N/A ILE 41.A N GLU 24.A O no hydrogen 3.118 N/A ILE 42.A N LEU 82.A O no hydrogen 2.906 N/A LEU 44.A N THR 80.A O no hydrogen 2.838 N/A GLU 45.A N ASP 43.A OD1 no hydrogen 2.963 N/A ALA 47.A N ASP 43.A O no hydrogen 2.973 N/A ILE 51.A N GLU 48.A O no hydrogen 3.336 N/A ILE 54.A N GLU 50.A O no hydrogen 3.078 N/A GLN 55.A N ILE 51.A O no hydrogen 2.956 N/A GLN 56.A N GLU 52.A O no hydrogen 2.919 N/A GLU 57.A N ASP 53.A O no hydrogen 2.990 N/A ILE 58.A N ILE 54.A O no hydrogen 2.969 N/A THR 59.A N GLN 55.A O no hydrogen 2.889 N/A THR 59.A OG1 GLN 55.A O no hydrogen 3.117 N/A VAL 60.A N GLN 56.A O no hydrogen 3.059 N/A LEU 61.A N GLU 57.A O no hydrogen 3.001 N/A SER 62.A N ILE 58.A O no hydrogen 2.864 N/A SER 62.A OG ILE 58.A O no hydrogen 3.305 N/A SER 62.A OG THR 59.A O no hydrogen 2.566 N/A GLN 63.A N THR 59.A O no hydrogen 3.191 N/A GLN 63.A N VAL 60.A O no hydrogen 3.072 N/A CYS 64.A N LEU 61.A O no hydrogen 3.099 N/A CYS 64.A SG VAL 60.A O no hydrogen 3.429 N/A ASP 65.A N TYR 121.A OH no hydrogen 2.836 N/A TYR 68.A N SER 66.A OG no hydrogen 2.982 N/A VAL 69.A N SER 66.A O no hydrogen 3.298 N/A THR 70.A N LEU 147.A O no hydrogen 2.947 N/A THR 70.A OG1 LEU 147.A O no hydrogen 2.897 N/A LYS 71.A N GLU 87.A OE1 no hydrogen 2.883 N/A LYS 71.A NZ ASP 65.A OD1 no hydrogen 3.259 N/A TYR 72.A OH SER 75.A OG no hydrogen 2.941 N/A TYR 73.A N ILE 85.A O no hydrogen 2.845 N/A SER 75.A OG THR 1.A OG1 no hydrogen 2.887 N/A SER 75.A OG TYR 72.A OH no hydrogen 2.941 N/A TYR 76.A N TRP 83.A O no hydrogen 2.900 N/A LEU 77.A N ASN 2.A O no hydrogen 3.294 N/A LYS 78.A N LYS 81.A O no hydrogen 2.969 N/A LYS 78.A NZ ASP 6.A OD1 no hydrogen 2.958 N/A LYS 78.A NZ ASP 6.A OD2 no hydrogen 2.772 N/A LYS 78.A NZ GLU 8.A OE1 no hydrogen 3.125 N/A THR 80.A OG1 ASP 43.A OD1 no hydrogen 3.456 N/A LYS 81.A N LYS 78.A O no hydrogen 2.948 N/A LEU 82.A N ILE 42.A O no hydrogen 2.760 N/A TRP 83.A N TYR 76.A O no hydrogen 2.734 N/A ILE 84.A N LYS 40.A O no hydrogen 2.744 N/A ILE 85.A N GLY 74.A O no hydrogen 2.964 N/A MET 86.A N ALA 38.A O no hydrogen 2.798 N/A GLU 87.A N LYS 71.A O no hydrogen 2.873 N/A GLY 91.A N LEU 139.A O no hydrogen 2.684 N/A GLY 92.A N LEU 89.A O no hydrogen 3.372 N/A SER 93.A N ASP 96.A OD2 no hydrogen 3.081 N/A ALA 94.A N VAL 137.A O no hydrogen 2.725 N/A LEU 95.A N ALA 134.A O no hydrogen 3.187 N/A ASP 96.A N SER 93.A OG no hydrogen 2.991 N/A LEU 97.A N SER 93.A O no hydrogen 3.142 N/A LEU 98.A N LEU 95.A O no hydrogen 3.120 N/A GLU 99.A N ASP 96.A O no hydrogen 3.068 N/A GLY 101.A N LEU 98.A O no hydrogen 3.382 N/A ASP 104.A N GLN 107.A OE1 no hydrogen 2.936 N/A THR 106.A OG1 ASN 249.A O no hydrogen 3.396 N/A GLN 107.A N ASP 104.A OD1 no hydrogen 2.778 N/A ILE 108.A N ASP 104.A O no hydrogen 2.964 N/A ALA 109.A N GLU 105.A O no hydrogen 2.868 N/A THR 110.A N THR 106.A O no hydrogen 2.892 N/A THR 110.A OG1 THR 106.A O no hydrogen 2.692 N/A THR 110.A OG1 LYS 251.A O no hydrogen 3.531 N/A ILE 111.A N GLN 107.A O no hydrogen 2.969 N/A LEU 112.A N ILE 108.A O no hydrogen 2.865 N/A ARG 113.A N ALA 109.A O no hydrogen 2.892 N/A ARG 113.A NE GLU 114.A OE1 no hydrogen 2.913 N/A ARG 113.A NH2 GLU 114.A OE1 no hydrogen 3.237 N/A ARG 113.A NH2 LYS 251.A O no hydrogen 2.805 N/A GLU 114.A N THR 110.A O no hydrogen 3.130 N/A ILE 115.A N ILE 111.A O no hydrogen 2.930 N/A LEU 116.A N LEU 112.A O no hydrogen 2.838 N/A LYS 117.A N ARG 113.A O no hydrogen 2.911 N/A LYS 117.A NZ GLU 114.A OE1 no hydrogen 3.057 N/A GLY 118.A N GLU 114.A O no hydrogen 3.075 N/A LEU 119.A N ILE 115.A O no hydrogen 2.855 N/A ASP 120.A N LEU 116.A O no hydrogen 2.779 N/A TYR 121.A N LYS 117.A O no hydrogen 3.079 N/A LEU 122.A N GLY 118.A O no hydrogen 2.951 N/A HIS 123.A N LEU 119.A O no hydrogen 2.783 N/A HIS 123.A NE2 ASP 173.A OD2 no hydrogen 2.869 N/A SER 124.A N ASP 120.A O no hydrogen 2.974 N/A SER 124.A OG ASP 120.A O no hydrogen 3.277 N/A SER 124.A OG TYR 121.A O no hydrogen 2.686 N/A GLU 125.A N TYR 121.A O no hydrogen 3.019 N/A LYS 126.A N HIS 123.A O no hydrogen 3.129 N/A LYS 127.A N LEU 122.A O no hydrogen 2.928 N/A LYS 127.A NZ GLN 63.A OE1 no hydrogen 3.013 N/A HIS 129.A N ASP 173.A OD2 no hydrogen 2.814 N/A HIS 129.A NE2 ALA 148.A O no hydrogen 2.802 N/A ARG 130.A N ASP 173.A OD1 no hydrogen 2.879 N/A ARG 130.A NE TYR 168.A OH no hydrogen 2.893 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.025 N/A ALA 134.A N GLU 183.A OE1 no hydrogen 2.933 N/A ASN 136.A N LYS 133.A O no hydrogen 2.933 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.895 N/A ASN 136.A ND2 ASP 131.A OD2 no hydrogen 3.055 N/A VAL 137.A N ALA 134.A O no hydrogen 3.336 N/A LEU 138.A N LYS 146.A O no hydrogen 2.861 N/A LEU 139.A N GLY 92.A O no hydrogen 2.796 N/A SER 140.A N GLU 144.A O no hydrogen 2.802 N/A SER 140.A OG GLU 144.A OE2 no hydrogen 2.558 N/A HIS 142.A N SER 140.A OG no hydrogen 3.021 N/A GLY 143.A N SER 140.A O no hydrogen 3.026 N/A GLU 144.A N SER 140.A OG no hydrogen 3.139 N/A LYS 146.A N LEU 138.A O no hydrogen 2.795 N/A LYS 146.A NZ GLU 87.A OE1 no hydrogen 3.200 N/A LYS 146.A NZ GLU 87.A OE2 no hydrogen 2.648 N/A LEU 147.A N TYR 68.A O no hydrogen 2.817 N/A ALA 148.A N ASN 136.A O no hydrogen 2.877 N/A GLY 151.A N HIS 129.A O no hydrogen 2.893 N/A TRP 157.A NE1 GLU 183.A OE1 no hydrogen 2.897 N/A MET 158.A N PRO 155.A O no hydrogen 3.019 N/A GLU 161.A N GLU 161.A OE1 no hydrogen 2.707 N/A ILE 163.A N ALA 159.A O no hydrogen 3.203 N/A LYS 164.A N PRO 160.A O no hydrogen 2.910 N/A GLN 165.A N VAL 162.A O no hydrogen 3.076 N/A SER 166.A N GLU 161.A O no hydrogen 2.964 N/A LYS 171.A N ASP 169.A OD1 no hydrogen 2.843 N/A LYS 171.A NZ PRO 231.A O no hydrogen 3.288 N/A LYS 171.A NZ ARG 234.A O no hydrogen 2.572 N/A ALA 172.A N ASP 169.A O no hydrogen 3.061 N/A ASP 173.A N SER 170.A O no hydrogen 3.010 N/A TRP 175.A N LYS 171.A O no hydrogen 3.123 N/A SER 176.A N ALA 172.A O no hydrogen 3.039 N/A SER 176.A OG TRP 157.A O no hydrogen 2.753 N/A SER 176.A OG ALA 172.A O no hydrogen 3.284 N/A LEU 177.A N ASP 173.A O no hydrogen 2.854 N/A GLY 178.A N ILE 174.A O no hydrogen 3.039 N/A ILE 179.A N TRP 175.A O no hydrogen 3.025 N/A THR 180.A N SER 176.A O no hydrogen 2.831 N/A THR 180.A OG1 SER 176.A O no hydrogen 2.850 N/A ALA 181.A N LEU 177.A O no hydrogen 2.751 N/A ILE 182.A N GLY 178.A O no hydrogen 3.140 N/A GLU 183.A N ILE 179.A O no hydrogen 2.893 N/A LEU 184.A N THR 180.A O no hydrogen 2.781 N/A ALA 185.A N ALA 181.A O no hydrogen 3.048 N/A ARG 186.A N ILE 182.A O no hydrogen 2.739 N/A ARG 186.A NH1 GLU 212.A O no hydrogen 3.066 N/A GLY 187.A N GLU 183.A O no hydrogen 2.754 N/A SER 192.A OG GLU 188.A OE2 no hydrogen 3.083 N/A SER 192.A OG PRO 189.A O no hydrogen 3.511 N/A GLU 193.A N GLU 193.A OE1 no hydrogen 2.655 N/A LEU 194.A N HIS 191.A O no hydrogen 2.926 N/A MET 197.A N HIS 195.A ND1 no hydrogen 3.103 N/A VAL 199.A N HIS 195.A O no hydrogen 3.117 N/A LEU 200.A N PRO 196.A O no hydrogen 2.924 N/A PHE 201.A N LYS 198.A O no hydrogen 3.136 N/A LEU 202.A N LYS 198.A O no hydrogen 2.964 N/A ILE 203.A N VAL 199.A O no hydrogen 3.017 N/A LYS 205.A N PHE 201.A O no hydrogen 3.077 N/A ASN 206.A N LEU 202.A O no hydrogen 2.773 N/A THR 210.A OG1 GLU 212.A OE2 no hydrogen 2.790 N/A TYR 215.A N GLY 213.A O no hydrogen 2.907 N/A TYR 215.A OH ALA 185.A O no hydrogen 2.861 N/A SER 216.A N GLU 105.A OE2 no hydrogen 2.862 N/A SER 216.A OG GLU 105.A OE1 no hydrogen 2.588 N/A LEU 219.A N SER 216.A OG no hydrogen 3.284 N/A LYS 220.A N SER 216.A O no hydrogen 3.066 N/A LYS 220.A NZ GLY 213.A O no hydrogen 2.957 N/A GLU 221.A N LYS 217.A O no hydrogen 2.820 N/A PHE 222.A N PRO 218.A O no hydrogen 2.852 N/A VAL 223.A N LEU 219.A O no hydrogen 3.051 N/A GLU 224.A N LYS 220.A O no hydrogen 2.907 N/A ALA 225.A N GLU 221.A O no hydrogen 2.846 N/A CYS 226.A N PHE 222.A O no hydrogen 3.189 N/A CYS 226.A SG PHE 222.A O no hydrogen 3.514 N/A LEU 227.A N VAL 223.A O no hydrogen 2.915 N/A LYS 229.A NZ PRO 204.A O no hydrogen 3.075 N/A LYS 229.A NZ ASN 206.A O no hydrogen 2.756 N/A GLU 230.A N ASN 228.A OD1 no hydrogen 2.972 N/A SER 232.A N GLU 230.A OE1 no hydrogen 2.960 N/A SER 232.A OG GLU 230.A OE1 no hydrogen 2.781 N/A PHE 233.A N GLU 230.A O no hydrogen 2.935 N/A ARG 234.A N PRO 231.A O no hydrogen 2.988 N/A ARG 234.A NE ASN 228.A O no hydrogen 2.817 N/A ARG 234.A NH1 GLU 161.A OE2 no hydrogen 2.688 N/A ARG 234.A NH1 LYS 171.A O no hydrogen 2.934 N/A ARG 234.A NH2 GLU 161.A OE1 no hydrogen 2.877 N/A ARG 234.A NH2 GLU 161.A OE2 no hydrogen 3.452 N/A ARG 234.A NH2 ASN 228.A O no hydrogen 3.188 N/A THR 236.A N GLU 239.A OE1 no hydrogen 3.101 N/A LYS 238.A NZ ASP 120.A OD1 no hydrogen 2.786 N/A LYS 238.A NZ ASP 120.A OD2 no hydrogen 3.541 N/A GLU 239.A N THR 236.A OG1 no hydrogen 3.121 N/A LEU 240.A N THR 236.A O no hydrogen 2.981 N/A LEU 241.A N ALA 237.A O no hydrogen 3.014 N/A LYS 242.A N GLU 239.A O no hydrogen 2.970 N/A HIS 243.A N LEU 240.A O no hydrogen 3.002 N/A LYS 244.A NZ GLU 221.A OE1 no hydrogen 2.770 N/A PHE 245.A N HIS 243.A ND1 no hydrogen 3.034 N/A LEU 247.A N HIS 243.A O no hydrogen 2.945 N/A ARG 248.A N LYS 244.A O no hydrogen 2.859 N/A ASN 249.A N PHE 245.A O no hydrogen 3.213 N/A ASN 249.A N ILE 246.A O no hydrogen 3.293 N/A ASN 249.A ND2 PHE 245.A O no hydrogen 2.946 N/A ALA 250.A N ILE 246.A O no hydrogen 2.882 N/A LYS 251.A N THR 110.A OG1 no hydrogen 3.066 N/A TYR 255.A N LYS 252.A O no hydrogen 3.157 N/A LEU 256.A N THR 253.A O no hydrogen 2.845 N/A THR 257.A N SER 254.A O no hydrogen 3.093 N/A THR 257.A OG1 SER 254.A O no hydrogen 2.916 N/A GLU 258.A N TYR 255.A O no hydrogen 3.114 N/A ILE 260.A N LEU 256.A O no hydrogen 3.039 N/A ASP 261.A N THR 257.A O no hydrogen 2.798 N/A ALA 262.A N GLU 258.A O no hydrogen 2.980 N/A HIS 263.A N LEU 259.A O no hydrogen 3.200 N/A HIS 263.A NE2 GLU 99.A OE1 no hydrogen 3.025 N/A HIS 264.A N ILE 260.A O no hydrogen 3.005 N/A HIS 265.A N ASP 261.A O no hydrogen 2.880 N/A HIS 266.A N ALA 262.A O no hydrogen 3.005 N/A HIS 267.A N HIS 264.A O no hydrogen 3.334 N/A