Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8c1m_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N ASP 6.A OD2 no hydrogen 3.232 N/A ASP 6.A N ALA 3.A O no hydrogen 2.903 N/A PHE 7.A N LEU 4.A O no hydrogen 3.087 N/A GLU 8.A N ARG 25.A O no hydrogen 2.856 N/A GLY 10.A N LEU 23.A O no hydrogen 2.812 N/A LEU 13.A N VAL 21.A O no hydrogen 2.882 N/A GLY 14.A N VAL 21.A O no hydrogen 3.365 N/A GLY 16.A N GLY 19.A O no hydrogen 3.202 N/A GLY 19.A N GLY 16.A O no hydrogen 3.479 N/A VAL 21.A N GLY 14.A O no hydrogen 2.982 N/A TYR 22.A N LEU 35.A O no hydrogen 2.899 N/A LEU 23.A N ARG 11.A O no hydrogen 2.905 N/A ALA 24.A N LEU 33.A O no hydrogen 2.917 N/A ARG 25.A N GLU 8.A O no hydrogen 2.880 N/A GLU 26.A N PHE 31.A O no hydrogen 3.033 N/A LYS 27.A N ASP 6.A O no hydrogen 3.411 N/A LYS 27.A NZ GLU 5.A O no hydrogen 2.937 N/A GLN 28.A N GLU 26.A OE2 no hydrogen 3.163 N/A SER 29.A N LYS 27.A O no hydrogen 3.015 N/A SER 29.A OG GLU 26.A OE1 no hydrogen 3.361 N/A SER 29.A OG GLN 28.A O no hydrogen 2.533 N/A LYS 30.A N GLU 26.A O no hydrogen 2.835 N/A LYS 30.A NZ LYS 27.A O no hydrogen 3.146 N/A LEU 33.A N ALA 24.A O no hydrogen 2.878 N/A ALA 34.A N LEU 84.A O no hydrogen 2.865 N/A LEU 35.A N TYR 22.A O no hydrogen 2.845 N/A LYS 36.A N LEU 82.A O no hydrogen 2.947 N/A LYS 36.A NZ GLU 55.A OE2 no hydrogen 3.053 N/A VAL 37.A N ASN 20.A O no hydrogen 2.930 N/A LEU 38.A N VAL 80.A O no hydrogen 2.848 N/A PHE 39.A N PHE 18.A O no hydrogen 2.981 N/A LYS 40.A N THR 78.A O no hydrogen 2.872 N/A LYS 40.A NZ ASP 76.A O no hydrogen 2.769 N/A GLN 42.A NE2 LYS 17.A O no hydrogen 3.519 N/A LEU 43.A N PHE 39.A O no hydrogen 3.126 N/A GLU 44.A N LYS 40.A O no hydrogen 2.873 N/A LYS 45.A N ALA 41.A O no hydrogen 2.887 N/A ALA 46.A N GLN 42.A O no hydrogen 3.096 N/A GLY 47.A N LEU 43.A O no hydrogen 2.895 N/A GLY 47.A N GLU 44.A O no hydrogen 3.132 N/A VAL 48.A N LEU 43.A O no hydrogen 3.045 N/A GLU 49.A N GLU 49.A OE1 no hydrogen 3.063 N/A LEU 52.A N VAL 48.A O no hydrogen 2.892 N/A ARG 53.A N GLU 49.A O no hydrogen 3.063 N/A ARG 53.A NE GLU 57.A OE1 no hydrogen 2.936 N/A ARG 53.A NH2 GLU 57.A OE1 no hydrogen 3.534 N/A ARG 54.A N HIS 50.A O no hydrogen 3.141 N/A GLU 55.A N GLN 51.A O no hydrogen 2.894 N/A VAL 56.A N LEU 52.A O no hydrogen 3.006 N/A GLU 57.A N ARG 53.A O no hydrogen 2.908 N/A ILE 58.A N ARG 54.A O no hydrogen 2.982 N/A GLN 59.A N GLU 55.A O no hydrogen 3.023 N/A GLN 59.A NE2 LEU 68.A O no hydrogen 3.455 N/A SER 60.A N VAL 56.A O no hydrogen 3.162 N/A SER 60.A OG VAL 56.A O no hydrogen 2.455 N/A SER 60.A OG GLU 57.A O no hydrogen 3.276 N/A HIS 61.A N ILE 58.A O no hydrogen 3.245 N/A LEU 62.A N GLN 59.A O no hydrogen 3.320 N/A ARG 63.A N TYR 120.A OH no hydrogen 2.913 N/A ASN 66.A N HIS 64.A ND1 no hydrogen 2.964 N/A ASN 66.A ND2 LEU 144.A O no hydrogen 2.863 N/A ILE 67.A N HIS 64.A O no hydrogen 3.140 N/A LEU 68.A N ILE 146.A O no hydrogen 2.947 N/A TYR 71.A N ILE 83.A O no hydrogen 2.878 N/A PHE 74.A N TYR 81.A O no hydrogen 3.306 N/A ASP 76.A N ARG 79.A O no hydrogen 3.017 N/A ARG 79.A N ASP 76.A OD2 no hydrogen 2.869 N/A ARG 79.A NE TYR 81.A OH no hydrogen 2.737 N/A ARG 79.A NH2 TYR 81.A OH no hydrogen 3.174 N/A VAL 80.A N LEU 38.A O no hydrogen 2.836 N/A TYR 81.A N PHE 74.A O no hydrogen 2.851 N/A LEU 82.A N LYS 36.A O no hydrogen 2.875 N/A ILE 83.A N GLY 72.A O no hydrogen 2.909 N/A LEU 84.A N ALA 34.A O no hydrogen 2.848 N/A GLU 85.A N ARG 69.A O no hydrogen 3.031 N/A LEU 89.A N LEU 138.A O no hydrogen 3.011 N/A VAL 92.A N LEU 136.A O no hydrogen 2.879 N/A ARG 94.A N THR 91.A OG1 no hydrogen 2.935 N/A GLU 95.A N THR 91.A O no hydrogen 3.350 N/A LEU 96.A N VAL 92.A O no hydrogen 3.052 N/A LEU 96.A N TYR 93.A O no hydrogen 3.246 N/A GLN 97.A N TYR 93.A O no hydrogen 3.068 N/A GLN 97.A N ARG 94.A O no hydrogen 3.019 N/A LYS 98.A N ARG 94.A O no hydrogen 3.044 N/A LEU 99.A N GLU 95.A O no hydrogen 3.150 N/A PHE 102.A N PHE 195.A O no hydrogen 2.832 N/A ARG 106.A N ASP 103.A OD1 no hydrogen 2.854 N/A ARG 106.A NH2 TYR 110.A OH no hydrogen 2.793 N/A THR 107.A N ASP 103.A O no hydrogen 3.168 N/A THR 107.A OG1 ASP 103.A O no hydrogen 2.968 N/A ALA 108.A N GLU 104.A O no hydrogen 3.019 N/A THR 109.A N GLN 105.A O no hydrogen 3.019 N/A THR 109.A OG1 GLN 105.A O no hydrogen 2.599 N/A TYR 110.A N ARG 106.A O no hydrogen 2.867 N/A ILE 111.A N THR 107.A O no hydrogen 2.821 N/A THR 112.A N ALA 108.A O no hydrogen 3.035 N/A THR 112.A OG1 ALA 108.A O no hydrogen 2.299 N/A GLU 113.A N THR 109.A O no hydrogen 2.982 N/A LEU 114.A N TYR 110.A O no hydrogen 2.869 N/A ALA 115.A N ILE 111.A O no hydrogen 2.876 N/A ASN 116.A N THR 112.A O no hydrogen 2.913 N/A ALA 117.A N GLU 113.A O no hydrogen 3.134 N/A LEU 118.A N LEU 114.A O no hydrogen 2.948 N/A SER 119.A N ALA 115.A O no hydrogen 3.093 N/A SER 119.A OG ALA 115.A O no hydrogen 2.672 N/A CYS 121.A N ALA 117.A O no hydrogen 3.276 N/A CYS 121.A SG ALA 117.A O no hydrogen 3.591 N/A HIS 122.A N LEU 118.A O no hydrogen 2.789 N/A HIS 122.A NE2 ASP 184.A OD2 no hydrogen 2.872 N/A SER 123.A N SER 119.A O no hydrogen 2.908 N/A SER 123.A OG TYR 120.A O no hydrogen 2.628 N/A LYS 124.A N CYS 121.A O no hydrogen 3.066 N/A ARG 125.A N HIS 122.A O no hydrogen 3.100 N/A ARG 125.A NH1 ALA 155.A O no hydrogen 3.253 N/A VAL 126.A N CYS 121.A O no hydrogen 2.884 N/A ILE 127.A N VAL 153.A O no hydrogen 2.895 N/A HIS 128.A N ASP 184.A OD2 no hydrogen 3.099 N/A HIS 128.A NE2 ALA 147.A O no hydrogen 2.909 N/A ARG 129.A N ASP 184.A OD1 no hydrogen 2.878 N/A ARG 129.A NE TRP 151.A O no hydrogen 2.838 N/A ARG 129.A NH1 ARG 159.A O no hydrogen 2.960 N/A ARG 129.A NH2 TRP 151.A O no hydrogen 3.191 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 3.067 N/A LYS 132.A NZ THR 165.A OG1 no hydrogen 3.070 N/A ASN 135.A N LYS 132.A O no hydrogen 2.880 N/A LEU 136.A N PRO 133.A O no hydrogen 3.220 N/A LEU 137.A N LYS 145.A O no hydrogen 2.833 N/A LEU 138.A N GLY 90.A O no hydrogen 2.749 N/A GLY 139.A N GLU 143.A O no hydrogen 2.801 N/A ALA 141.A N GLU 143.A OE1 no hydrogen 2.825 N/A GLY 142.A N GLY 139.A O no hydrogen 2.895 N/A GLU 143.A N GLU 143.A OE1 no hydrogen 2.810 N/A LEU 144.A N GLU 113.A OE2 no hydrogen 3.128 N/A LYS 145.A NZ PRO 65.A O no hydrogen 2.802 N/A LYS 145.A NZ GLU 85.A OE1 no hydrogen 3.510 N/A LYS 145.A NZ GLU 85.A OE2 no hydrogen 3.367 N/A ILE 146.A N ASN 66.A O no hydrogen 2.912 N/A ALA 147.A N ASN 135.A O no hydrogen 2.891 N/A SER 152.A N PHE 149.A O no hydrogen 3.179 N/A SER 152.A OG PHE 149.A O no hydrogen 2.705 N/A VAL 153.A N ILE 127.A O no hydrogen 3.065 N/A ALA 155.A N ARG 125.A O no hydrogen 2.826 N/A SER 157.A N HIS 179.A O no hydrogen 3.062 N/A TYR 168.A OH GLU 194.A OE1 no hydrogen 2.578 N/A TYR 168.A OH GLU 194.A OE2 no hydrogen 3.423 N/A LEU 169.A N LEU 166.A O no hydrogen 2.866 N/A GLU 172.A N GLU 172.A OE1 no hydrogen 2.858 N/A MET 173.A N PRO 170.A O no hydrogen 2.913 N/A ILE 174.A N PRO 170.A O no hydrogen 3.217 N/A GLU 175.A N PRO 171.A O no hydrogen 3.142 N/A GLY 176.A N MET 173.A O no hydrogen 3.174 N/A ARG 177.A N GLU 172.A O no hydrogen 2.980 N/A ARG 177.A NH1 GLU 175.A OE1 no hydrogen 2.635 N/A HIS 179.A N SER 157.A O no hydrogen 2.889 N/A LYS 182.A N ASP 180.A OD1 no hydrogen 3.422 N/A LYS 182.A NZ ARG 244.A O no hydrogen 2.771 N/A LYS 182.A NZ PRO 245.A O no hydrogen 2.974 N/A VAL 183.A N ASP 180.A O no hydrogen 3.047 N/A TRP 186.A N LYS 182.A O no hydrogen 3.288 N/A TRP 186.A N VAL 183.A O no hydrogen 3.122 N/A SER 187.A N VAL 183.A O no hydrogen 3.150 N/A SER 187.A OG TYR 168.A O no hydrogen 2.961 N/A SER 187.A OG VAL 183.A O no hydrogen 3.330 N/A LEU 188.A N ASP 184.A O no hydrogen 3.055 N/A GLY 189.A N TRP 186.A O no hydrogen 2.959 N/A VAL 190.A N TRP 186.A O no hydrogen 3.105 N/A LEU 191.A N SER 187.A O no hydrogen 3.015 N/A CYS 192.A N LEU 188.A O no hydrogen 2.993 N/A TYR 193.A N GLY 189.A O no hydrogen 2.993 N/A TYR 193.A OH THR 220.A O no hydrogen 2.733 N/A GLU 194.A N VAL 190.A O no hydrogen 2.866 N/A PHE 195.A N LEU 191.A O no hydrogen 2.831 N/A LEU 196.A N CYS 192.A O no hydrogen 3.362 N/A VAL 197.A N TYR 193.A O no hydrogen 2.906 N/A GLY 198.A N GLU 194.A O no hydrogen 2.792 N/A THR 210.A N THR 206.A O no hydrogen 3.122 N/A THR 210.A OG1 THR 206.A O no hydrogen 3.461 N/A TYR 211.A N TYR 207.A O no hydrogen 2.976 N/A LYS 212.A N GLN 208.A O no hydrogen 3.084 N/A ARG 213.A N GLU 209.A O no hydrogen 2.885 N/A ARG 213.A NE PHE 202.A O no hydrogen 3.438 N/A ILE 214.A N THR 210.A O no hydrogen 2.864 N/A SER 215.A N TYR 211.A O no hydrogen 2.954 N/A SER 215.A OG TYR 211.A O no hydrogen 2.690 N/A SER 215.A OG LYS 212.A O no hydrogen 3.073 N/A ARG 216.A N LYS 212.A O no hydrogen 2.964 N/A VAL 217.A N ILE 214.A O no hydrogen 3.169 N/A GLU 218.A N ARG 213.A O no hydrogen 2.829 N/A VAL 225.A N PRO 222.A O no hydrogen 3.142 N/A THR 226.A OG1 GLU 104.A OE2 no hydrogen 2.625 N/A ALA 229.A N THR 226.A O no hydrogen 2.907 N/A ARG 230.A N THR 226.A O no hydrogen 2.892 N/A ARG 230.A NE VAL 225.A O no hydrogen 2.885 N/A ASP 231.A N GLU 227.A O no hydrogen 2.987 N/A LEU 232.A N GLY 228.A O no hydrogen 3.400 N/A ILE 233.A N ALA 229.A O no hydrogen 2.906 N/A SER 234.A N ARG 230.A O no hydrogen 3.070 N/A SER 234.A OG ARG 230.A O no hydrogen 2.716 N/A ARG 235.A N ASP 231.A O no hydrogen 3.004 N/A ARG 235.A NH1 GLU 249.A OE2 no hydrogen 3.423 N/A LEU 236.A N LEU 232.A O no hydrogen 3.056 N/A LEU 237.A N ILE 233.A O no hydrogen 2.892 N/A ASN 240.A ND2 GLN 243.A OE1 no hydrogen 3.106 N/A SER 242.A N ASN 240.A OD1 no hydrogen 3.258 N/A SER 242.A OG ASN 240.A OD1 no hydrogen 2.974 N/A GLN 243.A N ASN 240.A O no hydrogen 3.042 N/A ARG 244.A N PRO 241.A O no hydrogen 3.213 N/A ARG 244.A NE LYS 238.A O no hydrogen 2.902 N/A ARG 244.A NH1 GLU 172.A OE2 no hydrogen 2.775 N/A ARG 244.A NH1 LYS 182.A O no hydrogen 2.929 N/A ARG 244.A NH2 GLU 172.A OE1 no hydrogen 3.197 N/A ARG 244.A NH2 LYS 238.A O no hydrogen 3.023 N/A MET 246.A N GLU 249.A OE1 no hydrogen 3.294 N/A GLU 249.A N MET 246.A O no hydrogen 3.197 N/A VAL 250.A N LEU 247.A O no hydrogen 3.241 N/A LEU 251.A N LEU 247.A O no hydrogen 3.065 N/A GLU 252.A N ARG 248.A O no hydrogen 2.888 N/A HIS 253.A N VAL 250.A O no hydrogen 3.205 N/A HIS 253.A NE2 ASP 231.A OD2 no hydrogen 2.510 N/A TRP 255.A N HIS 253.A ND1 no hydrogen 3.027 N/A TRP 255.A NE1 GLU 104.A OE2 no hydrogen 2.880 N/A ILE 256.A N HIS 253.A O no hydrogen 2.950 N/A THR 257.A N HIS 253.A O no hydrogen 3.028 N/A THR 257.A OG1 HIS 253.A O no hydrogen 3.280 N/A THR 257.A OG1 PRO 254.A O no hydrogen 2.961 N/A ALA 258.A N PRO 254.A O no hydrogen 3.052 N/A ASN 259.A N ILE 256.A O no hydrogen 3.100 N/A ASN 259.A ND2 TRP 255.A O no hydrogen 2.863 N/A SER 260.A N ILE 256.A O no hydrogen 2.871 N/A SER 260.A OG ILE 256.A O no hydrogen 3.017 N/A SER 261.A N THR 109.A OG1 no hydrogen 3.366 N/A LYS 262.A NZ SER 260.A O no hydrogen 3.363 N/A LYS 262.A NZ SER 260.A OG no hydrogen 3.144 N/A