Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8c2s_F.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 12.A N LYS 8.A O no hydrogen 2.904 N/A ARG 12.A NE GLU 261.A O no hydrogen 2.485 N/A ARG 12.A NH1 LEU 7.A O no hydrogen 2.711 N/A PHE 14.A N GLU 261.A OE1 no hydrogen 2.891 N/A THR 15.A OG1 ILE 13.A O no hydrogen 2.977 N/A TYR 18.A OH THR 259.A O no hydrogen 3.012 N/A ARG 24.A N ASP 22.A OD1 no hydrogen 2.712 N/A ARG 24.A NE ASP 22.A OD1 no hydrogen 3.200 N/A LEU 25.A N GLU 147.A OE1 no hydrogen 2.851 N/A ALA 28.A N ARG 24.A O no hydrogen 2.884 N/A LEU 29.A N LEU 25.A O no hydrogen 2.880 N/A ARG 30.A N LYS 26.A O no hydrogen 2.872 N/A ARG 31.A N GLY 27.A O no hydrogen 2.915 N/A ASP 33.A N ALA 28.A O no hydrogen 2.839 N/A TRP 34.A N GLU 112.A OE1 no hydrogen 2.991 N/A TYR 35.A N GLY 32.A O no hydrogen 3.056 N/A THR 37.A OG1 GLU 112.A OE2 no hydrogen 3.081 N/A ILE 40.A N LYS 36.A O no hydrogen 2.921 N/A LEU 41.A N THR 37.A O no hydrogen 2.885 N/A LEU 42.A N LYS 38.A O no hydrogen 3.463 N/A LYS 43.A N GLU 39.A O no hydrogen 2.999 N/A LYS 43.A N ILE 40.A O no hydrogen 3.159 N/A GLY 44.A N LEU 41.A O no hydrogen 3.514 N/A LEU 49.A N PRO 45.A O no hydrogen 2.956 N/A GLY 50.A N ASP 46.A O no hydrogen 2.846 N/A GLU 51.A N TRP 47.A O no hydrogen 2.884 N/A MET 52.A N ILE 48.A O no hydrogen 2.970 N/A LYS 53.A N LEU 49.A O no hydrogen 2.880 N/A THR 54.A N GLY 50.A O no hydrogen 2.907 N/A THR 54.A OG1 GLY 50.A O no hydrogen 2.869 N/A THR 54.A OG1 GLU 51.A O no hydrogen 3.016 N/A SER 55.A N GLU 51.A O no hydrogen 2.866 N/A SER 55.A OG MET 52.A O no hydrogen 2.386 N/A GLY 56.A N MET 52.A O no hydrogen 2.956 N/A GLY 56.A N LYS 53.A O no hydrogen 3.128 N/A LEU 57.A N SER 55.A OG no hydrogen 3.172 N/A GLY 59.A N PHE 65.A O no hydrogen 2.828 N/A ARG 60.A N THR 219.A OG1 no hydrogen 3.217 N/A THR 67.A N LEU 57.A O no hydrogen 2.540 N/A LYS 70.A N PRO 66.A O no hydrogen 2.883 N/A LYS 70.A NZ GLU 181.A OE2 no hydrogen 3.454 N/A LYS 70.A NZ VAL 214.A O no hydrogen 3.283 N/A TRP 71.A N THR 67.A O no hydrogen 2.908 N/A SER 72.A N GLY 68.A O no hydrogen 2.913 N/A SER 72.A OG LEU 69.A O no hydrogen 2.812 N/A PHE 73.A N LYS 70.A O no hydrogen 3.470 N/A MET 74.A N TRP 71.A O no hydrogen 3.158 N/A ASN 75.A N SER 72.A O no hydrogen 3.213 N/A ARG 81.A NE GLY 209.A O no hydrogen 2.646 N/A ARG 81.A NH2 ASP 204.A O no hydrogen 3.386 N/A ARG 81.A NH2 GLY 209.A O no hydrogen 2.671 N/A LYS 83.A NZ MET 74.A O no hydrogen 3.017 N/A LYS 83.A NZ LYS 76.A O no hydrogen 3.465 N/A LYS 83.A NZ MET 121.A O no hydrogen 3.474 N/A TYR 84.A N PRO 211.A O no hydrogen 2.925 N/A LEU 85.A N ALA 125.A O no hydrogen 2.923 N/A VAL 86.A N THR 213.A O no hydrogen 2.927 N/A ASN 88.A N ALA 215.A O no hydrogen 2.902 N/A ALA 89.A N VAL 87.A O no hydrogen 3.110 N/A ALA 89.A N TYR 129.A O no hydrogen 2.918 N/A ASP 90.A N ASN 88.A OD1 no hydrogen 2.843 N/A THR 96.A N GLU 93.A O no hydrogen 2.974 N/A THR 96.A OG1 GLU 93.A O no hydrogen 2.985 N/A CYS 97.A SG GLY 95.A O no hydrogen 3.415 N/A LYS 98.A NZ ARG 60.A O no hydrogen 3.474 N/A LYS 98.A NZ GLU 218.A OE1 no hydrogen 2.932 N/A ASP 99.A N GLU 91.A OE2 no hydrogen 2.960 N/A ARG 100.A N GLU 91.A OE1 no hydrogen 2.962 N/A ARG 100.A NE GLU 137.A OE2 no hydrogen 2.662 N/A ARG 100.A NH2 GLU 137.A OE2 no hydrogen 3.316 N/A ILE 102.A N LYS 98.A O no hydrogen 3.034 N/A MET 103.A N ASP 99.A O no hydrogen 2.865 N/A ARG 104.A N ARG 100.A O no hydrogen 3.022 N/A ARG 104.A NE GLU 101.A OE1 no hydrogen 3.161 N/A ARG 104.A NH2 GLU 101.A OE1 no hydrogen 2.609 N/A ARG 104.A NH2 GLU 101.A OE2 no hydrogen 3.078 N/A HIS 105.A N GLU 101.A O no hydrogen 2.966 N/A LYS 109.A NZ ALA 221.A O no hydrogen 2.824 N/A LYS 109.A NZ THR 225.A OG1 no hydrogen 2.683 N/A VAL 111.A N PRO 107.A O no hydrogen 3.010 N/A GLU 112.A N HIS 108.A O no hydrogen 2.863 N/A GLY 113.A N LYS 109.A O no hydrogen 2.892 N/A CYS 114.A N LEU 110.A O no hydrogen 2.870 N/A CYS 114.A SG LEU 110.A O no hydrogen 2.866 N/A LEU 115.A N VAL 111.A O no hydrogen 2.993 N/A VAL 116.A N GLU 112.A O no hydrogen 2.938 N/A GLY 117.A N GLY 113.A O no hydrogen 2.894 N/A GLY 118.A N CYS 114.A O no hydrogen 2.845 N/A ARG 119.A N LEU 115.A O no hydrogen 3.006 N/A ARG 119.A NE LEU 41.A O no hydrogen 2.918 N/A ALA 120.A N VAL 116.A O no hydrogen 2.901 N/A MET 121.A N GLY 117.A O no hydrogen 2.868 N/A GLY 122.A N ARG 119.A O no hydrogen 3.358 N/A ALA 123.A N GLY 118.A O no hydrogen 2.528 N/A ARG 124.A N LYS 83.A O no hydrogen 3.039 N/A ALA 126.A N ASP 166.A O no hydrogen 2.905 N/A TYR 127.A N LEU 85.A O no hydrogen 2.890 N/A ILE 128.A N PHE 168.A O no hydrogen 2.909 N/A TYR 129.A N VAL 87.A O no hydrogen 2.888 N/A ILE 130.A N VAL 170.A O no hydrogen 2.909 N/A ARG 131.A NH1 GLU 91.A O no hydrogen 2.547 N/A GLU 133.A N GLU 133.A OE1 no hydrogen 3.036 N/A PHE 134.A N ARG 131.A O no hydrogen 3.000 N/A GLU 137.A N GLU 137.A OE1 no hydrogen 2.519 N/A SER 139.A N TYR 135.A O no hydrogen 2.905 N/A SER 139.A OG TYR 135.A O no hydrogen 2.433 N/A ASN 140.A N ASN 136.A O no hydrogen 2.913 N/A LEU 141.A N GLU 137.A O no hydrogen 2.945 N/A GLN 142.A N ALA 138.A O no hydrogen 2.888 N/A VAL 143.A N SER 139.A O no hydrogen 2.928 N/A ALA 144.A N ASN 140.A O no hydrogen 2.978 N/A ILE 145.A N LEU 141.A O no hydrogen 2.875 N/A ARG 146.A N GLN 142.A O no hydrogen 2.897 N/A GLU 147.A N VAL 143.A O no hydrogen 2.931 N/A ALA 148.A N ALA 144.A O no hydrogen 2.927 N/A TYR 149.A N ILE 145.A O no hydrogen 2.881 N/A GLU 150.A N ARG 146.A O no hydrogen 2.903 N/A ALA 151.A N GLU 147.A O no hydrogen 2.925 N/A GLY 152.A N TYR 149.A O no hydrogen 3.037 N/A LEU 153.A N ALA 148.A O no hydrogen 3.126 N/A ALA 158.A N TYR 163.A O no hydrogen 2.430 N/A CYS 159.A SG LEU 153.A O no hydrogen 3.144 N/A SER 161.A OG ALA 158.A O no hydrogen 3.075 N/A SER 161.A OG GLY 160.A O no hydrogen 2.570 N/A TYR 163.A OH GLY 118.A O no hydrogen 3.108 N/A VAL 167.A N TYR 149.A OH no hydrogen 3.132 N/A PHE 168.A N ALA 126.A O no hydrogen 2.894 N/A VAL 170.A N ILE 128.A O no hydrogen 2.857 N/A ARG 171.A NH2 GLY 132.A O no hydrogen 3.019 N/A TYR 176.A N GLU 349.A OE2 no hydrogen 3.477 N/A CYS 178.A N ALA 175.A O no hydrogen 2.656 N/A CYS 178.A SG TYR 129.A OH no hydrogen 3.199 N/A CYS 178.A SG SER 187.A OG no hydrogen 3.587 N/A GLY 179.A N TYR 176.A O no hydrogen 3.163 N/A GLU 180.A N ILE 177.A O no hydrogen 2.815 N/A LEU 184.A N GLU 180.A O no hydrogen 2.863 N/A ILE 185.A N GLU 181.A O no hydrogen 2.974 N/A GLU 186.A N THR 182.A O no hydrogen 2.946 N/A SER 187.A N ALA 183.A O no hydrogen 2.911 N/A ILE 188.A N LEU 184.A O no hydrogen 2.853 N/A GLU 189.A N ILE 185.A O no hydrogen 2.952 N/A GLY 190.A N SER 187.A O no hydrogen 2.657 N/A LYS 191.A N GLU 186.A O no hydrogen 3.185 N/A LYS 194.A N GLN 192.A O no hydrogen 2.567 N/A ARG 196.A N THR 182.A OG1 no hydrogen 2.574 N/A ASP 204.A N PHE 201.A O no hydrogen 2.806 N/A VAL 205.A N PHE 201.A O no hydrogen 3.034 N/A VAL 205.A N PRO 202.A O no hydrogen 2.971 N/A VAL 207.A N THR 212.A OG1 no hydrogen 3.089 N/A GLY 209.A N GLY 206.A O no hydrogen 2.655 N/A CYS 210.A N VAL 207.A O no hydrogen 3.130 N/A CYS 210.A SG VAL 207.A O no hydrogen 3.904 N/A CYS 210.A SG PHE 208.A O no hydrogen 3.560 N/A THR 212.A N PRO 202.A O no hydrogen 3.423 N/A THR 212.A OG1 CYS 210.A O no hydrogen 2.764 N/A ALA 215.A N VAL 86.A O no hydrogen 2.897 N/A ASN 216.A ND2 ARG 60.A O no hydrogen 3.163 N/A GLU 218.A N ASN 216.A OD1 no hydrogen 3.053 N/A VAL 220.A N ASN 216.A O no hydrogen 2.996 N/A ALA 221.A N VAL 217.A O no hydrogen 2.828 N/A VAL 222.A N GLU 218.A O no hydrogen 2.957 N/A SER 223.A N VAL 220.A O no hydrogen 2.944 N/A ILE 226.A N VAL 222.A O no hydrogen 3.229 N/A CYS 227.A N SER 223.A O no hydrogen 2.916 N/A CYS 227.A SG SER 223.A O no hydrogen 2.822 N/A CYS 227.A SG SER 223.A OG no hydrogen 3.574 N/A ARG 228.A N PRO 224.A O no hydrogen 2.871 N/A ARG 228.A NH1 TYR 35.A O no hydrogen 3.218 N/A ARG 228.A NH1 GLU 112.A OE1 no hydrogen 3.422 N/A ARG 228.A NH2 GLU 112.A OE1 no hydrogen 3.046 N/A ARG 229.A N THR 225.A O no hydrogen 2.902 N/A ARG 229.A NH1 GLU 10.A O no hydrogen 2.598 N/A GLY 230.A N ILE 226.A O no hydrogen 2.873 N/A PHE 234.A N GLY 231.A O no hydrogen 3.119 N/A GLY 236.A N THR 232.A O no hydrogen 2.868 N/A PHE 237.A N PHE 234.A O no hydrogen 3.087 N/A ARG 239.A NE ASN 242.A OD1 no hydrogen 3.030 N/A ARG 239.A NH2 ASN 242.A OD1 no hydrogen 2.665 N/A ARG 241.A NE ASP 312.A OD2 no hydrogen 3.343 N/A SER 243.A OG SER 55.A O no hydrogen 2.783 N/A THR 245.A OG1 GLU 262.A O no hydrogen 2.094 N/A LYS 246.A NZ LEU 247.A O no hydrogen 3.535 N/A LYS 246.A NZ THR 323.A O no hydrogen 2.604 N/A LEU 247.A N GLU 218.A OE2 no hydrogen 3.072 N/A PHE 248.A N VAL 260.A O no hydrogen 2.875 N/A ASN 249.A ND2 THR 259.A OG1 no hydrogen 3.060 N/A ILE 250.A N CYS 258.A O no hydrogen 2.883 N/A SER 251.A N VAL 326.A O no hydrogen 2.936 N/A HIS 253.A N VAL 328.A O no hydrogen 3.051 N/A ASN 255.A N VAL 279.A O no hydrogen 2.653 N/A HIS 256.A ND1 ASN 255.A O no hydrogen 2.828 N/A CYS 258.A N ILE 250.A O no hydrogen 2.945 N/A CYS 258.A SG HIS 275.A O no hydrogen 3.270 N/A VAL 260.A N PHE 248.A O no hydrogen 2.916 N/A SER 265.A N MET 309.A O no hydrogen 2.702 N/A SER 265.A N ASP 310.A OD1 no hydrogen 2.964 N/A LEU 268.A N VAL 307.A O no hydrogen 3.357 N/A LEU 271.A N PRO 267.A O no hydrogen 2.895 N/A ILE 272.A N LEU 268.A O no hydrogen 2.849 N/A GLU 273.A N LYS 269.A O no hydrogen 3.023 N/A LYS 274.A N GLU 270.A O no hydrogen 2.845 N/A ALA 276.A N GLU 273.A O no hydrogen 3.000 N/A VAL 279.A N GLY 277.A O no hydrogen 2.841 N/A THR 280.A OG1 VAL 279.A O no hydrogen 2.731 N/A ASN 285.A N GLY 282.A O no hydrogen 2.960 N/A ASN 285.A ND2 THR 280.A O no hydrogen 3.497 N/A LEU 286.A N TRP 283.A O no hydrogen 3.234 N/A LEU 287.A N MET 329.A O no hydrogen 3.122 N/A VAL 289.A N ILE 299.A O no hydrogen 3.143 N/A ILE 290.A N ILE 327.A O no hydrogen 2.850 N/A SER 295.A OG TYR 346.A OH no hydrogen 1.975 N/A THR 296.A N GLY 293.A O no hydrogen 2.572 N/A THR 296.A OG1 GLY 293.A O no hydrogen 3.139 N/A THR 296.A OG1 GLY 320.A O no hydrogen 3.467 N/A ILE 299.A N VAL 289.A O no hydrogen 3.255 N/A LYS 301.A NZ TRP 283.A O no hydrogen 2.455 N/A CYS 304.A N PRO 300.A O no hydrogen 2.997 N/A CYS 304.A SG LYS 301.A O no hydrogen 3.117 N/A GLU 305.A N LYS 301.A O no hydrogen 2.883 N/A THR 306.A N VAL 303.A O no hydrogen 3.158 N/A VAL 307.A N VAL 303.A O no hydrogen 2.915 N/A VAL 307.A N CYS 304.A O no hydrogen 3.282 N/A MET 309.A N VAL 266.A O no hydrogen 3.099 N/A LEU 314.A N ASP 310.A O no hydrogen 2.887 N/A VAL 315.A N PHE 311.A O no hydrogen 2.915 N/A GLN 316.A N ASP 312.A O no hydrogen 2.889 N/A ALA 317.A N ALA 313.A O no hydrogen 2.937 N/A GLN 318.A N VAL 315.A O no hydrogen 2.730 N/A THR 319.A N LEU 314.A O no hydrogen 2.870 N/A THR 319.A OG1 LEU 314.A O no hydrogen 3.187 N/A THR 323.A OG1 GLU 93.A OE1 no hydrogen 3.074 N/A VAL 326.A N ASN 249.A O no hydrogen 2.847 N/A ILE 327.A N ILE 290.A O no hydrogen 2.962 N/A VAL 328.A N SER 251.A O no hydrogen 2.913 N/A MET 329.A N ALA 288.A O no hydrogen 2.944 N/A ARG 331.A NH2 ASP 284.A O no hydrogen 3.525 N/A SER 332.A N ASP 330.A OD1 no hydrogen 2.957 N/A LYS 337.A N ASP 334.A OD1 no hydrogen 3.160 N/A ALA 338.A N ASP 334.A O no hydrogen 2.932 N/A ILE 339.A N ILE 335.A O no hydrogen 2.956 N/A ALA 340.A N VAL 336.A O no hydrogen 2.881 N/A ARG 341.A N LYS 337.A O no hydrogen 2.915 N/A LEU 342.A N ALA 338.A O no hydrogen 3.043 N/A ILE 343.A N ILE 339.A O no hydrogen 2.929 N/A GLU 344.A N ALA 340.A O no hydrogen 2.884 N/A PHE 345.A N ARG 341.A O no hydrogen 2.905 N/A TYR 346.A N LEU 342.A O no hydrogen 2.970 N/A TYR 346.A OH SER 295.A OG no hydrogen 1.975 N/A LYS 347.A N ILE 343.A O no hydrogen 2.892 N/A HIS 348.A N GLU 344.A O no hydrogen 2.952 N/A GLU 349.A N PHE 345.A O no hydrogen 2.930 N/A GLU 349.A N TYR 346.A O no hydrogen 3.073 N/A GLN 353.A NE2 PRO 195.A O no hydrogen 3.627 N/A ARG 358.A N CYS 354.A O no hydrogen 3.081 N/A ARG 358.A NE GLY 352.A O no hydrogen 3.137 N/A GLU 359.A N THR 355.A O no hydrogen 2.944 N/A GLY 360.A N PRO 356.A O no hydrogen 2.906 N/A VAL 361.A N CYS 357.A O no hydrogen 2.859 N/A TRP 363.A N GLU 359.A O no hydrogen 2.971 N/A MET 364.A N GLY 360.A O no hydrogen 2.814 N/A ASN 365.A N VAL 361.A O no hydrogen 2.852 N/A LYS 366.A N ASP 362.A O no hydrogen 2.915 N/A VAL 367.A N TRP 363.A O no hydrogen 2.988 N/A MET 368.A N MET 364.A O no hydrogen 2.818 N/A ALA 369.A N ASN 365.A O no hydrogen 2.920 N/A ARG 370.A N LYS 366.A O no hydrogen 2.971 N/A ARG 370.A NH1 GLU 380.A OE1 no hydrogen 2.837 N/A ARG 370.A NH2 GLU 380.A OE1 no hydrogen 3.292 N/A ARG 370.A NH2 GLU 380.A OE2 no hydrogen 2.886 N/A PHE 371.A N VAL 367.A O no hydrogen 2.882 N/A VAL 372.A N MET 368.A O no hydrogen 2.852 N/A LYS 373.A N ALA 369.A O no hydrogen 2.990 N/A GLY 374.A N PHE 371.A O no hydrogen 2.748 N/A ALA 376.A N GLY 374.A O no hydrogen 2.962 N/A ARG 377.A N GLU 380.A OE2 no hydrogen 2.739 N/A GLU 380.A N ARG 377.A O no hydrogen 2.956 N/A ILE 381.A N PRO 378.A O no hydrogen 3.472 N/A SER 383.A OG GLU 380.A O no hydrogen 2.392 N/A LEU 384.A N GLU 380.A O no hydrogen 2.929 N/A TRP 385.A N ILE 381.A O no hydrogen 2.904 N/A GLU 386.A N ASP 382.A O no hydrogen 2.884 N/A ILE 387.A N SER 383.A O no hydrogen 2.901 N/A SER 388.A N LEU 384.A O no hydrogen 2.912 N/A SER 388.A OG LEU 384.A O no hydrogen 2.832 N/A LYS 389.A N TRP 385.A O no hydrogen 2.943 N/A GLN 390.A N GLU 386.A O no hydrogen 2.868 N/A ILE 391.A N ILE 387.A O no hydrogen 2.958 N/A GLU 392.A N LYS 389.A O no hydrogen 3.028 N/A THR 395.A OG1 CYS 397.A O no hydrogen 2.433 N/A THR 395.A OG1 ASP 401.A OD1 no hydrogen 3.198 N/A GLY 402.A N ALA 398.A O no hydrogen 2.902 N/A ALA 403.A N LEU 399.A O no hydrogen 2.866 N/A ALA 404.A N GLY 400.A O no hydrogen 2.892 N/A TRP 405.A N ASP 401.A O no hydrogen 2.942 N/A GLN 408.A N ALA 404.A O no hydrogen 3.069 N/A GLY 409.A N TRP 405.A O no hydrogen 2.893 N/A LEU 410.A N PRO 406.A O no hydrogen 2.943 N/A ILE 411.A N VAL 407.A O no hydrogen 2.910 N/A ARG 412.A N GLN 408.A O no hydrogen 2.844 N/A HIS 413.A N GLY 409.A O no hydrogen 3.002 N/A PHE 414.A N LEU 410.A O no hydrogen 2.909 N/A ARG 415.A NH2 ASP 382.A OD2 no hydrogen 3.228 N/A LEU 418.A N PHE 414.A O no hydrogen 3.236 N/A GLU 419.A N ARG 415.A O no hydrogen 2.953 N/A ASP 420.A N PRO 416.A O no hydrogen 2.909 N/A ARG 421.A N GLU 417.A O no hydrogen 2.888 N/A ARG 421.A NE GLU 417.A OE2 no hydrogen 3.042 N/A ARG 421.A NH1 ASP 334.A OD1 no hydrogen 3.201 N/A ARG 421.A NH1 ASP 334.A OD2 no hydrogen 3.533 N/A ARG 421.A NH1 VAL 372.A O no hydrogen 3.369 N/A ARG 421.A NH2 ASP 334.A OD1 no hydrogen 2.976 N/A ARG 421.A NH2 GLU 417.A OE2 no hydrogen 3.005 N/A MET 422.A N LEU 418.A O no hydrogen 2.932 N/A GLN 423.A N GLU 419.A O no hydrogen 2.901 N/A ARG 424.A N ASP 420.A O no hydrogen 2.891 N/A ARG 424.A NH1 ASP 420.A OD2 no hydrogen 3.144 N/A PHE 425.A N ARG 421.A O no hydrogen 2.944 N/A ALA 426.A N MET 422.A O no hydrogen 2.874 N/A GLN 427.A N GLN 423.A O no hydrogen 2.923 N/A GLN 428.A N ARG 424.A O no hydrogen 2.901 N/A