Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8c2s_N.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N ASN 1.A O no hydrogen 2.972 N/A ALA 6.A N PRO 2.A O no hydrogen 2.867 N/A ILE 7.A N ILE 3.A O no hydrogen 2.934 N/A ILE 8.A N THR 4.A O no hydrogen 2.850 N/A TYR 9.A N LEU 5.A O no hydrogen 2.916 N/A PHE 10.A N ALA 6.A O no hydrogen 2.860 N/A THR 11.A N ILE 7.A O no hydrogen 2.862 N/A THR 11.A OG1 ILE 7.A O no hydrogen 3.102 N/A ILE 12.A N ILE 8.A O no hydrogen 2.931 N/A PHE 13.A N TYR 9.A O no hydrogen 2.933 N/A LEU 14.A N PHE 10.A O no hydrogen 2.815 N/A GLY 15.A N THR 11.A O no hydrogen 2.954 N/A ILE 18.A N LEU 14.A O no hydrogen 2.849 N/A THR 19.A N GLY 15.A O no hydrogen 2.953 N/A THR 19.A OG1 GLY 15.A O no hydrogen 3.050 N/A MET 20.A N PRO 16.A O no hydrogen 2.908 N/A SER 21.A N VAL 17.A O no hydrogen 2.918 N/A SER 21.A N ILE 18.A O no hydrogen 3.266 N/A SER 21.A OG VAL 17.A O no hydrogen 3.229 N/A SER 22.A OG ILE 18.A O no hydrogen 2.605 N/A LEU 25.A N TRP 83.A O no hydrogen 2.918 N/A LEU 27.A N ASN 24.A OD1 no hydrogen 3.136 N/A MET 28.A N ASN 24.A O no hydrogen 2.957 N/A TRP 29.A N LEU 25.A O no hydrogen 2.900 N/A TRP 29.A NE1 SER 66.A O no hydrogen 3.101 N/A VAL 30.A N MET 26.A O no hydrogen 2.851 N/A GLY 31.A N LEU 27.A O no hydrogen 2.926 N/A LEU 32.A N MET 28.A O no hydrogen 2.992 N/A GLU 33.A N TRP 29.A O no hydrogen 2.934 N/A PHE 34.A N VAL 30.A O no hydrogen 2.887 N/A SER 35.A N GLY 31.A O no hydrogen 3.039 N/A SER 35.A OG GLY 31.A O no hydrogen 3.116 N/A SER 35.A OG LEU 32.A O no hydrogen 2.514 N/A LEU 36.A N LEU 32.A O no hydrogen 2.949 N/A LEU 37.A N GLU 33.A O no hydrogen 2.882 N/A ALA 38.A N PHE 34.A O no hydrogen 2.970 N/A ILE 39.A N SER 35.A O no hydrogen 3.009 N/A LEU 43.A N ILE 39.A O no hydrogen 3.058 N/A ILE 44.A N ILE 40.A O no hydrogen 2.901 N/A ASN 45.A N MET 42.A O no hydrogen 3.384 N/A LYS 47.A N ILE 44.A O no hydrogen 3.246 N/A SER 51.A N ASN 48.A OD1 no hydrogen 2.591 N/A SER 51.A OG ASN 48.A OD1 no hydrogen 3.067 N/A THR 52.A N ASN 48.A O no hydrogen 2.978 N/A THR 52.A OG1 PRO 49.A O no hydrogen 2.877 N/A GLU 53.A N PRO 49.A O no hydrogen 3.319 N/A ALA 54.A N ARG 50.A O no hydrogen 2.929 N/A ALA 55.A N SER 51.A O no hydrogen 2.943 N/A THR 56.A N THR 52.A O no hydrogen 2.940 N/A THR 56.A OG1 GLU 53.A O no hydrogen 2.643 N/A LYS 57.A N GLU 53.A O no hydrogen 2.959 N/A TYR 58.A N ALA 54.A O no hydrogen 2.993 N/A PHE 59.A N ALA 55.A O no hydrogen 2.875 N/A VAL 60.A N THR 56.A O no hydrogen 2.948 N/A THR 61.A N LYS 57.A O no hydrogen 3.069 N/A THR 61.A OG1 LYS 57.A O no hydrogen 2.874 N/A GLN 62.A N TYR 58.A O no hydrogen 2.945 N/A ALA 63.A N PHE 59.A O no hydrogen 2.906 N/A THR 64.A N VAL 60.A O no hydrogen 3.044 N/A THR 64.A OG1 VAL 60.A O no hydrogen 2.949 N/A ALA 65.A N THR 61.A O no hydrogen 3.014 N/A SER 66.A N GLN 62.A O no hydrogen 2.907 N/A SER 66.A OG GLU 33.A OE2 no hydrogen 2.342 N/A SER 66.A OG GLN 62.A O no hydrogen 3.491 N/A MET 67.A N ALA 63.A O no hydrogen 2.985 N/A ILE 68.A N THR 64.A O no hydrogen 3.032 N/A ILE 69.A N ALA 65.A O no hydrogen 2.994 N/A LEU 70.A N SER 66.A O no hydrogen 2.879 N/A LEU 71.A N MET 67.A O no hydrogen 2.906 N/A ALA 72.A N ILE 68.A O no hydrogen 2.994 N/A ILE 73.A N ILE 69.A O no hydrogen 2.934 N/A VAL 74.A N LEU 70.A O no hydrogen 2.894 N/A LEU 75.A N LEU 71.A O no hydrogen 2.931 N/A ASN 76.A N ALA 72.A O no hydrogen 2.942 N/A ASN 76.A ND2 MET 84.A O no hydrogen 3.019 N/A TYR 77.A N ILE 73.A O no hydrogen 2.911 N/A LYS 78.A N VAL 74.A O no hydrogen 2.867 N/A GLN 79.A N LEU 75.A O no hydrogen 2.938 N/A GLN 79.A NE2 GLN 88.A O no hydrogen 3.040 N/A LEU 80.A N ASN 76.A O no hydrogen 2.919 N/A GLY 81.A N TYR 77.A O no hydrogen 2.844 N/A GLN 86.A N THR 89.A OG1 no hydrogen 2.911 N/A GLN 86.A NE2 MET 84.A O no hydrogen 3.692 N/A GLN 88.A N GLN 88.A OE1 no hydrogen 2.640 N/A THR 89.A N GLN 86.A O no hydrogen 2.871 N/A THR 89.A OG1 ASN 76.A OD1 no hydrogen 2.844 N/A THR 89.A OG1 GLN 86.A O no hydrogen 2.947 N/A ASN 90.A N GLN 79.A OE1 no hydrogen 2.940 N/A LEU 92.A N ASN 90.A OD1 no hydrogen 3.351 N/A ILE 93.A N ASN 90.A O no hydrogen 3.188 N/A ASN 95.A N GLY 91.A O no hydrogen 2.953 N/A MET 96.A N LEU 92.A O no hydrogen 2.897 N/A THR 97.A N ILE 93.A O no hydrogen 2.943 N/A THR 97.A OG1 ILE 93.A O no hydrogen 2.893 N/A THR 97.A OG1 LEU 94.A O no hydrogen 2.477 N/A LEU 98.A N LEU 94.A O no hydrogen 2.928 N/A MET 99.A N ASN 95.A O no hydrogen 2.930 N/A ALA 100.A N MET 96.A O no hydrogen 2.874 N/A LEU 101.A N THR 97.A O no hydrogen 2.907 N/A SER 102.A N LEU 98.A O no hydrogen 2.856 N/A MET 103.A N MET 99.A O no hydrogen 2.954 N/A LYS 104.A N ALA 100.A O no hydrogen 2.935 N/A LYS 104.A NZ GLN 62.A O no hydrogen 3.192 N/A LYS 104.A NZ SER 66.A OG no hydrogen 3.278 N/A LEU 105.A N LEU 101.A O no hydrogen 2.870 N/A GLY 106.A N SER 102.A O no hydrogen 2.907 N/A GLY 106.A N MET 103.A O no hydrogen 3.222 N/A LEU 107.A N SER 102.A O no hydrogen 3.063 N/A ALA 108.A N SER 160.A OG no hydrogen 2.458 N/A TRP 113.A NE1 MET 103.A O no hydrogen 3.058 N/A LEU 114.A N HIS 111.A O no hydrogen 3.278 N/A VAL 117.A N TRP 113.A O no hydrogen 3.227 N/A THR 118.A N LEU 114.A O no hydrogen 2.952 N/A THR 118.A OG1 LEU 114.A O no hydrogen 2.998 N/A GLN 119.A N PRO 115.A O no hydrogen 2.897 N/A GLN 119.A NE2 GLN 173.A OE1 no hydrogen 3.119 N/A GLY 120.A N GLU 116.A O no hydrogen 2.920 N/A ILE 121.A N VAL 117.A O no hydrogen 2.962 N/A MET 125.A N PRO 122.A O no hydrogen 3.252 N/A GLY 126.A N PRO 122.A O no hydrogen 2.806 N/A LEU 127.A N LEU 123.A O no hydrogen 2.940 N/A LEU 129.A N MET 125.A O no hydrogen 2.936 N/A LEU 130.A N GLY 126.A O no hydrogen 2.906 N/A THR 131.A N ILE 128.A O no hydrogen 3.143 N/A THR 131.A OG1 LEU 127.A O no hydrogen 2.124 N/A TRP 132.A N ILE 128.A O no hydrogen 2.906 N/A TRP 132.A NE1 ILE 12.A O no hydrogen 3.031 N/A GLN 133.A N ILE 128.A O no hydrogen 3.275 N/A GLN 133.A NE2 TYR 58.A OH no hydrogen 3.155 N/A LYS 134.A N THR 131.A O no hydrogen 3.450 N/A LEU 138.A N LYS 134.A O no hydrogen 3.202 N/A SER 139.A N ILE 135.A O no hydrogen 2.890 N/A SER 139.A OG ALA 136.A O no hydrogen 2.448 N/A ILE 140.A N ALA 136.A O no hydrogen 2.895 N/A LEU 141.A N PRO 137.A O no hydrogen 2.987 N/A ILE 142.A N LEU 138.A O no hydrogen 2.858 N/A GLN 143.A N SER 139.A O no hydrogen 2.920 N/A GLN 143.A NE2 SER 139.A O no hydrogen 3.649 N/A ILE 144.A N LEU 141.A O no hydrogen 2.727 N/A TYR 145.A N ILE 142.A O no hydrogen 3.288 N/A LEU 147.A N ILE 144.A O no hydrogen 3.211 N/A LEU 148.A N TYR 145.A O no hydrogen 3.231 N/A THR 151.A N ASN 149.A OD1 no hydrogen 2.979 N/A ILE 153.A N ASN 149.A O no hydrogen 2.944 N/A LEU 154.A N SER 150.A O no hydrogen 2.891 N/A MET 155.A N THR 151.A O no hydrogen 2.916 N/A LEU 156.A N ILE 152.A O no hydrogen 2.930 N/A ALA 157.A N ILE 153.A O no hydrogen 2.878 N/A ILE 158.A N LEU 154.A O no hydrogen 2.909 N/A THR 159.A N MET 155.A O no hydrogen 2.930 N/A THR 159.A OG1 MET 155.A O no hydrogen 2.095 N/A SER 160.A N LEU 156.A O no hydrogen 2.894 N/A SER 160.A OG ALA 108.A O no hydrogen 3.527 N/A SER 160.A OG LEU 156.A O no hydrogen 3.404 N/A ILE 161.A N ALA 157.A O no hydrogen 2.892 N/A PHE 162.A N ILE 158.A O no hydrogen 2.965 N/A MET 163.A N THR 159.A O no hydrogen 2.877 N/A GLY 164.A N SER 160.A O no hydrogen 2.804 N/A ALA 165.A N ILE 161.A O no hydrogen 2.960 N/A TRP 166.A N PHE 162.A O no hydrogen 2.942 N/A GLY 167.A N MET 163.A O no hydrogen 2.850 N/A GLY 168.A N GLY 164.A O no hydrogen 2.940 N/A MET 174.A N MET 224.A O no hydrogen 3.438 N/A ARG 175.A NH1 ILE 121.A O no hydrogen 3.050 N/A ILE 177.A N GLN 173.A O no hydrogen 2.964 N/A MET 178.A N MET 174.A O no hydrogen 2.892 N/A ALA 179.A N ARG 175.A O no hydrogen 3.014 N/A TYR 180.A N LYS 176.A O no hydrogen 2.968 N/A SER 181.A N ILE 177.A O no hydrogen 2.931 N/A SER 182.A N MET 178.A O no hydrogen 2.930 N/A ILE 183.A N ALA 179.A O no hydrogen 3.002 N/A ALA 184.A N TYR 180.A O no hydrogen 3.007 N/A HIS 185.A N SER 181.A O no hydrogen 2.994 N/A MET 186.A N SER 182.A O no hydrogen 2.929 N/A GLY 187.A N ILE 183.A O no hydrogen 2.923 N/A TRP 188.A N ALA 184.A O no hydrogen 3.083 N/A MET 189.A N HIS 185.A O no hydrogen 2.972 N/A LEU 190.A N MET 186.A O no hydrogen 2.915 N/A ALA 191.A N GLY 187.A O no hydrogen 2.911 N/A ILE 192.A N TRP 188.A O no hydrogen 3.059 N/A LEU 193.A N LEU 190.A O no hydrogen 3.108 N/A ASN 196.A N ILE 192.A O no hydrogen 3.227 N/A ASN 196.A ND2 GLU 268.A OE1 no hydrogen 2.842 N/A SER 198.A OG ASN 196.A OD1 no hydrogen 3.449 N/A LEU 199.A N ASN 196.A O no hydrogen 3.019 N/A THR 200.A OG1 MET 189.A O no hydrogen 2.762 N/A LEU 201.A N PRO 197.A O no hydrogen 2.940 N/A LEU 202.A N SER 198.A O no hydrogen 2.907 N/A ASN 203.A N LEU 199.A O no hydrogen 2.880 N/A ASN 203.A ND2 HIS 185.A O no hydrogen 3.454 N/A LEU 204.A N THR 200.A O no hydrogen 2.926 N/A MET 205.A N LEU 201.A O no hydrogen 2.893 N/A ILE 206.A N LEU 202.A O no hydrogen 2.957 N/A TYR 207.A N ASN 203.A O no hydrogen 2.863 N/A ILE 208.A N LEU 204.A O no hydrogen 2.918 N/A ILE 209.A N MET 205.A O no hydrogen 2.871 N/A LEU 210.A N ILE 206.A O no hydrogen 2.911 N/A THR 211.A N TYR 207.A O no hydrogen 2.840 N/A THR 211.A OG1 TYR 207.A O no hydrogen 2.711 N/A ALA 212.A N ILE 208.A O no hydrogen 2.954 N/A MET 214.A N LEU 210.A O no hydrogen 3.462 N/A PHE 215.A N THR 211.A O no hydrogen 2.823 N/A MET 216.A N ALA 212.A O no hydrogen 2.945 N/A ALA 217.A N PRO 213.A O no hydrogen 2.860 N/A LEU 218.A N MET 214.A O no hydrogen 2.922 N/A MET 219.A N PHE 215.A O no hydrogen 2.880 N/A LEU 220.A N MET 216.A O no hydrogen 2.963 N/A LEU 220.A N ALA 217.A O no hydrogen 3.128 N/A ASN 222.A N MET 219.A O no hydrogen 3.128 N/A SER 223.A N LEU 218.A O no hydrogen 3.050 N/A ILE 226.A N THR 172.A O no hydrogen 3.338 N/A ILE 229.A N THR 225.A O no hydrogen 2.875 N/A SER 230.A N ILE 226.A O no hydrogen 2.925 N/A SER 230.A N ASN 227.A O no hydrogen 3.027 N/A SER 230.A OG ASN 227.A O no hydrogen 2.560 N/A LEU 231.A N SER 228.A O no hydrogen 3.085 N/A LEU 232.A N ILE 229.A O no hydrogen 3.320 N/A TRP 233.A NE1 PHE 304.A O no hydrogen 2.820 N/A ASN 234.A N LEU 231.A O no hydrogen 3.180 N/A LYS 235.A N LEU 231.A O no hydrogen 2.922 N/A THR 236.A N LEU 232.A O no hydrogen 2.876 N/A LEU 240.A N PRO 237.A O no hydrogen 3.229 N/A ILE 243.A N MET 239.A O no hydrogen 2.954 N/A SER 244.A N LEU 240.A O no hydrogen 2.899 N/A SER 244.A OG LEU 240.A O no hydrogen 3.100 N/A LEU 245.A N THR 241.A O no hydrogen 2.996 N/A MET 246.A N MET 242.A O no hydrogen 2.877 N/A LEU 247.A N ILE 243.A O no hydrogen 2.928 N/A LEU 248.A N SER 244.A O no hydrogen 2.966 N/A SER 249.A N LEU 245.A O no hydrogen 2.898 N/A LEU 250.A N MET 246.A O no hydrogen 2.921 N/A GLY 251.A N LEU 247.A O no hydrogen 2.910 N/A GLY 252.A N LEU 248.A O no hydrogen 2.890 N/A THR 257.A OG1 SER 332.A O no hydrogen 2.474 N/A THR 257.A OG1 THR 335.A OG1 no hydrogen 2.706 N/A GLY 258.A N SER 249.A OG no hydrogen 3.084 N/A PHE 259.A N LEU 256.A O no hydrogen 3.324 N/A LEU 260.A N THR 257.A O no hydrogen 2.612 N/A TRP 263.A N PHE 259.A O no hydrogen 2.694 N/A ILE 264.A N LEU 260.A O no hydrogen 2.903 N/A ILE 265.A N PRO 261.A O no hydrogen 2.905 N/A ILE 266.A N LYS 262.A O no hydrogen 2.883 N/A THR 267.A N TRP 263.A O no hydrogen 2.932 N/A THR 267.A OG1 TRP 263.A O no hydrogen 2.895 N/A GLU 268.A N ILE 264.A O no hydrogen 2.956 N/A LEU 269.A N ILE 265.A O no hydrogen 2.948 N/A MET 270.A N ILE 266.A O no hydrogen 2.903 N/A LYS 271.A N THR 267.A O no hydrogen 2.921 N/A LYS 271.A NZ GLU 268.A OE2 no hydrogen 3.468 N/A ASN 272.A N GLU 268.A O no hydrogen 2.971 N/A ASN 273.A N MET 270.A O no hydrogen 2.892 N/A CYS 274.A N LEU 269.A O no hydrogen 2.877 N/A CYS 274.A SG CYS 274.A O no hydrogen 2.799 N/A ALA 278.A N CYS 274.A O no hydrogen 2.941 N/A THR 279.A N LEU 275.A O no hydrogen 2.850 N/A THR 279.A OG1 LEU 275.A O no hydrogen 2.754 N/A LEU 280.A N ILE 276.A O no hydrogen 2.947 N/A MET 281.A N MET 277.A O no hydrogen 2.904 N/A ALA 282.A N ALA 278.A O no hydrogen 2.950 N/A MET 283.A N THR 279.A O no hydrogen 2.894 N/A MET 284.A N LEU 280.A O no hydrogen 2.918 N/A ALA 285.A N MET 281.A O no hydrogen 2.915 N/A ALA 285.A N ALA 282.A O no hydrogen 3.317 N/A LEU 286.A N MET 283.A O no hydrogen 3.265 N/A PHE 290.A N LEU 286.A O no hydrogen 2.938 N/A PHE 291.A N LEU 287.A O no hydrogen 2.948 N/A TYR 292.A N ASN 288.A O no hydrogen 2.939 N/A THR 293.A N LEU 289.A O no hydrogen 2.815 N/A THR 293.A OG1 LEU 289.A O no hydrogen 2.752 N/A ARG 294.A N PHE 290.A O no hydrogen 2.980 N/A ARG 294.A NH2 LEU 169.A O no hydrogen 3.471 N/A ILE 296.A N TYR 292.A O no hydrogen 2.940 N/A TYR 297.A N THR 293.A O no hydrogen 2.852 N/A SER 298.A N ARG 294.A O no hydrogen 2.933 N/A SER 298.A OG ARG 294.A O no hydrogen 3.507 N/A THR 299.A N LEU 295.A O no hydrogen 2.902 N/A THR 299.A OG1 LEU 295.A O no hydrogen 3.540 N/A THR 299.A OG1 SER 300.A OG no hydrogen 2.643 N/A SER 300.A N ILE 296.A O no hydrogen 2.896 N/A SER 300.A OG LEU 240.A O no hydrogen 3.451 N/A SER 300.A OG SER 244.A OG no hydrogen 2.341 N/A SER 300.A OG THR 299.A OG1 no hydrogen 2.643 N/A LEU 301.A N ILE 296.A O no hydrogen 3.322 N/A THR 302.A N TYR 297.A O no hydrogen 3.218 N/A THR 302.A OG1 TYR 297.A O no hydrogen 2.588 N/A THR 306.A OG1 SER 310.A OG no hydrogen 3.354 N/A ASN 307.A N THR 306.A OG1 no hydrogen 2.770 N/A SER 310.A OG THR 306.A OG1 no hydrogen 3.354 N/A SER 310.A OG ASN 307.A O no hydrogen 3.490 N/A LYS 311.A N ASN 308.A O no hydrogen 3.313 N/A MET 312.A N ASN 309.A O no hydrogen 3.236 N/A THR 314.A N SER 310.A O no hydrogen 2.935 N/A THR 314.A OG1 SER 310.A O no hydrogen 2.813 N/A HIS 315.A N LYS 311.A O no hydrogen 2.891 N/A GLN 316.A N MET 312.A O no hydrogen 2.925 N/A THR 327.A N LEU 323.A O no hydrogen 3.005 N/A THR 327.A OG1 LEU 323.A O no hydrogen 2.659 N/A LEU 328.A N MET 324.A O no hydrogen 2.881 N/A ALA 329.A N PHE 325.A O no hydrogen 2.882 N/A ILE 330.A N SER 326.A O no hydrogen 2.986 N/A MET 331.A N THR 327.A O no hydrogen 2.950 N/A SER 332.A N ALA 329.A O no hydrogen 3.255 N/A SER 332.A OG ALA 329.A O no hydrogen 3.093 N/A THR 333.A N ALA 329.A O no hydrogen 2.979 N/A THR 333.A N ILE 330.A O no hydrogen 3.197 N/A THR 333.A OG1 ALA 329.A O no hydrogen 3.090 N/A THR 335.A OG1 THR 257.A OG1 no hydrogen 2.706 N/A THR 335.A OG1 MET 331.A O no hydrogen 2.950 N/A LEU 338.A N THR 335.A O no hydrogen 2.945 N/A ALA 339.A N LEU 336.A O no hydrogen 2.541 N/A GLN 341.A N LEU 338.A O no hydrogen 3.190 N/A LEU 342.A N ALA 339.A O no hydrogen 2.760 N/A ILE 343.A N ALA 339.A O no hydrogen 3.317 N/A