Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8c7x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N TYR 71.A O no hydrogen 2.743 N/A GLN 8.A N PRO 5.A O no hydrogen 3.432 N/A THR 10.A N LYS 27.A O no hydrogen 2.969 N/A GLY 12.A N LYS 25.A O no hydrogen 2.673 N/A ILE 15.A N VAL 23.A O no hydrogen 2.770 N/A GLY 16.A N VAL 23.A O no hydrogen 3.379 N/A SER 17.A OG THR 22.A OG1 no hydrogen 2.844 N/A GLY 18.A N GLY 21.A O no hydrogen 2.930 N/A GLY 21.A N GLY 18.A O no hydrogen 3.084 N/A THR 22.A N MET 36.A O no hydrogen 2.938 N/A THR 22.A OG1 SER 17.A OG no hydrogen 2.844 N/A VAL 23.A N GLY 16.A O no hydrogen 2.877 N/A TYR 24.A N VAL 34.A O no hydrogen 2.808 N/A LYS 25.A N GLN 13.A O no hydrogen 2.920 N/A GLY 26.A N VAL 32.A O no hydrogen 2.874 N/A LYS 27.A N THR 10.A O no hydrogen 2.882 N/A LYS 27.A NZ ASP 31.A OD1 no hydrogen 2.913 N/A TRP 28.A N GLY 30.A O no hydrogen 2.810 N/A TRP 28.A NE1 GLN 8.A OE1 no hydrogen 2.930 N/A VAL 32.A N GLY 26.A O no hydrogen 2.940 N/A ALA 33.A N THR 81.A O no hydrogen 2.873 N/A VAL 34.A N TYR 24.A O no hydrogen 2.891 N/A LYS 35.A N ILE 79.A O no hydrogen 2.866 N/A LYS 35.A NZ GLU 53.A OE1 no hydrogen 2.865 N/A LYS 35.A NZ GLU 53.A OE2 no hydrogen 3.020 N/A MET 36.A N THR 22.A O no hydrogen 2.781 N/A LEU 37.A N LEU 77.A O no hydrogen 3.042 N/A ASN 38.A ND2 THR 40.A O no hydrogen 2.763 N/A THR 43.A N GLN 46.A OE1 no hydrogen 2.787 N/A GLN 46.A N THR 43.A OG1 no hydrogen 2.997 N/A LEU 47.A N THR 43.A O no hydrogen 2.945 N/A GLN 48.A N PRO 44.A O no hydrogen 2.844 N/A ALA 49.A N GLN 45.A O no hydrogen 2.887 N/A PHE 50.A N GLN 46.A O no hydrogen 2.934 N/A LYS 51.A N LEU 47.A O no hydrogen 2.919 N/A ASN 52.A N GLN 48.A O no hydrogen 2.937 N/A GLU 53.A N ALA 49.A O no hydrogen 2.965 N/A VAL 54.A N PHE 50.A O no hydrogen 2.978 N/A GLY 55.A N LYS 51.A O no hydrogen 2.907 N/A VAL 56.A N ASN 52.A O no hydrogen 2.872 N/A LEU 57.A N GLU 53.A O no hydrogen 2.921 N/A ARG 58.A N VAL 54.A O no hydrogen 2.867 N/A LYS 59.A N VAL 56.A O no hydrogen 3.107 N/A LYS 59.A NZ GLY 55.A O no hydrogen 2.780 N/A THR 60.A N LEU 57.A O no hydrogen 3.008 N/A THR 60.A OG1 LEU 57.A O no hydrogen 2.743 N/A ARG 61.A N TYR 118.A OH no hydrogen 2.896 N/A ASN 64.A N HIS 62.A ND1 no hydrogen 2.969 N/A ASN 64.A ND2 GLN 111.A OE1 no hydrogen 2.870 N/A ASN 64.A ND2 VAL 142.A O no hydrogen 2.927 N/A ILE 65.A N HIS 62.A O no hydrogen 3.125 N/A LEU 66.A N ILE 144.A O no hydrogen 2.904 N/A LEU 67.A N GLN 82.A OE1 no hydrogen 2.955 N/A MET 69.A N VAL 80.A O no hydrogen 2.822 N/A GLY 70.A N VAL 80.A O no hydrogen 3.073 N/A TYR 71.A N TRP 2.A O no hydrogen 3.044 N/A SER 72.A N ALA 78.A O no hydrogen 2.911 N/A SER 72.A OG ILE 4.A O no hydrogen 3.050 N/A GLN 76.A NE2 ASN 38.A O no hydrogen 2.757 N/A LEU 77.A N ASN 38.A OD1 no hydrogen 2.819 N/A ALA 78.A N SER 72.A O no hydrogen 2.875 N/A ILE 79.A N LYS 35.A O no hydrogen 2.862 N/A VAL 80.A N GLY 70.A O no hydrogen 2.853 N/A THR 81.A N ALA 33.A O no hydrogen 2.988 N/A THR 81.A OG1 GLN 82.A O no hydrogen 2.961 N/A GLN 82.A N LEU 67.A O no hydrogen 2.857 N/A TRP 83.A NE1 GLU 85.A OE1 no hydrogen 2.850 N/A GLU 85.A N HIS 137.A ND1 no hydrogen 3.003 N/A SER 88.A OG ASN 132.A OD1 no hydrogen 2.736 N/A LEU 89.A N ILE 134.A O no hydrogen 2.777 N/A TYR 90.A N SER 131.A O no hydrogen 3.128 N/A HIS 91.A N SER 88.A OG no hydrogen 3.003 N/A HIS 92.A N SER 88.A O no hydrogen 3.018 N/A HIS 92.A ND1 THR 98.A OG1 no hydrogen 2.892 N/A LEU 93.A N LEU 89.A O no hydrogen 2.889 N/A HIS 94.A N TYR 90.A O no hydrogen 2.826 N/A HIS 94.A NE2 GLU 200.A OE1 no hydrogen 2.706 N/A ALA 95.A N HIS 91.A O no hydrogen 3.040 N/A SER 96.A OG HIS 91.A O no hydrogen 2.777 N/A THR 98.A N HIS 92.A O no hydrogen 2.987 N/A THR 98.A OG1 HIS 92.A ND1 no hydrogen 2.892 N/A THR 98.A OG1 HIS 92.A O no hydrogen 3.457 N/A LYS 104.A NZ ASP 139.A O no hydrogen 2.729 N/A LEU 105.A N GLU 101.A O no hydrogen 2.950 N/A ILE 106.A N MET 102.A O no hydrogen 2.938 N/A ASP 107.A N LYS 103.A O no hydrogen 2.939 N/A ILE 108.A N LYS 104.A O no hydrogen 2.855 N/A ALA 109.A N LEU 105.A O no hydrogen 3.062 N/A ARG 110.A N ILE 106.A O no hydrogen 2.776 N/A ARG 110.A NE ASP 107.A OD1 no hydrogen 3.246 N/A ARG 110.A NH1 GLU 267.A OE1 no hydrogen 3.462 N/A ARG 110.A NH2 ASP 107.A OD1 no hydrogen 2.753 N/A GLN 111.A N ASP 107.A O no hydrogen 2.896 N/A GLN 111.A NE2 ASP 107.A OD2 no hydrogen 2.939 N/A GLN 111.A NE2 ASN 140.A O no hydrogen 3.187 N/A THR 112.A N ILE 108.A O no hydrogen 2.955 N/A THR 112.A OG1 ILE 108.A O no hydrogen 2.816 N/A ALA 113.A N ALA 109.A O no hydrogen 2.854 N/A ARG 114.A N ARG 110.A O no hydrogen 2.863 N/A ARG 114.A NE GLU 267.A OE2 no hydrogen 2.955 N/A ARG 114.A NH2 GLU 267.A OE1 no hydrogen 3.336 N/A ARG 114.A NH2 GLU 267.A OE2 no hydrogen 2.813 N/A GLY 115.A N GLN 111.A O no hydrogen 3.045 N/A MET 116.A N THR 112.A O no hydrogen 2.923 N/A ASP 117.A N ALA 113.A O no hydrogen 2.754 N/A TYR 118.A N ARG 114.A O no hydrogen 2.957 N/A LEU 119.A N GLY 115.A O no hydrogen 2.936 N/A HIS 120.A N MET 116.A O no hydrogen 2.937 N/A HIS 120.A NE2 ASP 190.A OD2 no hydrogen 2.831 N/A ALA 121.A N ASP 117.A O no hydrogen 2.884 N/A LYS 122.A N TYR 118.A O no hydrogen 3.017 N/A LYS 122.A N LEU 119.A O no hydrogen 2.973 N/A SER 123.A N HIS 120.A O no hydrogen 2.939 N/A ILE 124.A N LEU 119.A O no hydrogen 2.895 N/A HIS 126.A N ASP 190.A OD2 no hydrogen 2.823 N/A HIS 126.A NE2 GLY 145.A O no hydrogen 2.839 N/A ARG 127.A N ASP 190.A OD1 no hydrogen 3.090 N/A ARG 127.A NH1 ASN 183.A OD1 no hydrogen 3.099 N/A ASP 128.A N HIS 126.A ND1 no hydrogen 3.023 N/A LYS 130.A NZ GLY 167.A O no hydrogen 3.154 N/A LYS 130.A NZ SER 168.A OG no hydrogen 2.930 N/A SER 131.A OG GLU 200.A OE1 no hydrogen 2.597 N/A SER 131.A OG GLU 200.A OE2 no hydrogen 3.279 N/A ASN 133.A N LYS 130.A O no hydrogen 2.944 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.851 N/A ILE 134.A N SER 131.A O no hydrogen 3.254 N/A PHE 135.A N LYS 143.A O no hydrogen 2.817 N/A LEU 136.A N SER 87.A O no hydrogen 2.971 N/A HIS 137.A N THR 141.A O no hydrogen 2.873 N/A GLU 138.A N GLU 85.A O no hydrogen 2.797 N/A ASP 139.A N LEU 136.A O no hydrogen 3.367 N/A ASN 140.A N HIS 137.A O no hydrogen 2.909 N/A THR 141.A N HIS 137.A O no hydrogen 3.185 N/A THR 141.A OG1 GLU 138.A OE2.B no hydrogen 3.505 N/A VAL 142.A N GLN 111.A OE1 no hydrogen 2.908 N/A LYS 143.A N PHE 135.A O no hydrogen 2.865 N/A LYS 143.A NZ VAL 63.A O no hydrogen 2.761 N/A LYS 143.A NZ GLN 82.A OE1 no hydrogen 3.454 N/A ILE 144.A N ASN 64.A O no hydrogen 2.841 N/A GLY 145.A N ASN 133.A O no hydrogen 3.055 N/A PHE 147.A N ASN 133.A OD1 no hydrogen 3.004 N/A GLY 148.A N ASP 146.A OD1 no hydrogen 3.113 N/A THR 151.A N SER 19.A O no hydrogen 3.033 N/A LYS 153.A NZ ALA 150.A O no hydrogen 3.378 N/A LYS 153.A NZ THR 151.A O no hydrogen 2.935 N/A TRP 156.A N SER 154.A OG no hydrogen 3.110 N/A GLN 161.A NE2 TRP 156.A O no hydrogen 2.721 N/A LEU 165.A N GLN 161.A O no hydrogen 2.803 N/A SER 166.A N GLU 163.A O no hydrogen 2.959 N/A SER 166.A OG GLU 163.A O no hydrogen 3.234 N/A SER 168.A N LEU 165.A O no hydrogen 2.817 N/A SER 168.A OG ASP 128.A OD1 no hydrogen 2.667 N/A SER 168.A OG ASP 128.A OD2 no hydrogen 3.502 N/A TRP 171.A N SER 168.A O no hydrogen 3.004 N/A TRP 171.A NE1 GLU 200.A OE2 no hydrogen 2.775 N/A MET 172.A N ILE 169.A O no hydrogen 3.164 N/A GLU 175.A N GLU 175.A OE1 no hydrogen 2.811 N/A ILE 177.A N ALA 173.A O no hydrogen 2.933 N/A ARG 178.A N PRO 174.A O no hydrogen 3.001 N/A ARG 178.A NH2 GLY 222.A O no hydrogen 2.874 N/A MET 179.A N GLU 175.A O no hydrogen 3.186 N/A MET 179.A N VAL 176.A O no hydrogen 3.258 N/A TYR 185.A N ASN 183.A OD1 no hydrogen 3.285 N/A SER 186.A N SER 189.A OG no hydrogen 2.855 N/A SER 186.A OG GLN 188.A OE1 no hydrogen 3.342 N/A GLN 188.A N GLN 188.A OE1 no hydrogen 2.852 N/A GLN 188.A NE2 ASP 254.A OD1 no hydrogen 2.797 N/A SER 189.A N SER 186.A OG no hydrogen 2.973 N/A SER 189.A OG SER 186.A O no hydrogen 3.016 N/A ASP 190.A N SER 186.A O no hydrogen 3.183 N/A VAL 191.A N PHE 187.A O no hydrogen 2.982 N/A TYR 192.A N GLN 188.A O no hydrogen 3.043 N/A ALA 193.A N SER 189.A O no hydrogen 3.035 N/A PHE 194.A N ASP 190.A O no hydrogen 3.005 N/A GLY 195.A N VAL 191.A O no hydrogen 2.908 N/A ILE 196.A N TYR 192.A O no hydrogen 3.032 N/A VAL 197.A N ALA 193.A O no hydrogen 2.994 N/A LEU 198.A N PHE 194.A O no hydrogen 2.779 N/A TYR 199.A N GLY 195.A O no hydrogen 2.957 N/A TYR 199.A OH ASP 229.A O no hydrogen 2.886 N/A GLU 200.A N ILE 196.A O no hydrogen 2.873 N/A LEU 201.A N VAL 197.A O no hydrogen 2.916 N/A MET 202.A N LEU 198.A O no hydrogen 2.832 N/A THR 203.A N TYR 199.A O no hydrogen 2.852 N/A THR 203.A OG1 TYR 199.A O no hydrogen 2.773 N/A GLY 204.A N GLU 200.A O no hydrogen 2.818 N/A GLN 205.A N THR 203.A OG1 no hydrogen 2.831 N/A ILE 211.A N TYR 208.A O no hydrogen 3.008 N/A GLN 216.A N ASN 213.A OD1 no hydrogen 2.784 N/A ILE 218.A N ARG 214.A O no hydrogen 2.890 N/A GLU 219.A N ASP 215.A O no hydrogen 2.945 N/A MET 220.A N GLN 216.A O no hydrogen 2.913 N/A VAL 221.A N ILE 217.A O no hydrogen 2.817 N/A GLY 222.A N ILE 218.A O no hydrogen 3.058 N/A ARG 223.A N GLU 219.A O no hydrogen 2.979 N/A ARG 223.A NH2.B GLU 219.A OE2 no hydrogen 3.346 N/A GLY 224.A N MET 220.A O no hydrogen 2.952 N/A GLY 224.A N VAL 221.A O no hydrogen 3.202 N/A SER 225.A N MET 220.A O no hydrogen 2.893 N/A SER 225.A OG MET 220.A O no hydrogen 3.359 N/A LEU 226.A N MET 220.A O no hydrogen 3.313 N/A SER 231.A N ASP 229.A OD1 no hydrogen 3.150 N/A SER 231.A OG ASP 229.A OD1 no hydrogen 2.638 N/A LYS 232.A N ASP 229.A O no hydrogen 3.167 N/A VAL 233.A N LEU 230.A O no hydrogen 3.404 N/A ARG 234.A N MET 202.A O no hydrogen 2.901 N/A CYS 237.A N ARG 234.A O no hydrogen 2.921 N/A CYS 237.A SG PRO 238.A O no hydrogen 3.634 N/A ARG 240.A NE GLU 272.A OE1 no hydrogen 2.864 N/A ARG 240.A NE GLU 272.A OE2 no hydrogen 3.433 N/A ARG 240.A NH1 GLU 265.A OE2 no hydrogen 2.848 N/A ARG 240.A NH2 GLU 272.A OE2 no hydrogen 2.828 N/A MET 241.A N PRO 238.A O no hydrogen 2.897 N/A LYS 242.A N PRO 238.A O no hydrogen 3.253 N/A ARG 243.A N LYS 239.A O no hydrogen 3.329 N/A ARG 243.A NE GLU 247.A OE2 no hydrogen 2.862 N/A LEU 244.A N ARG 240.A O no hydrogen 3.031 N/A MET 245.A N MET 241.A O no hydrogen 2.960 N/A ALA 246.A N LYS 242.A O no hydrogen 3.190 N/A GLU 247.A N ARG 243.A O no hydrogen 2.992 N/A CYS 248.A N LEU 244.A O no hydrogen 2.932 N/A CYS 248.A SG LEU 244.A O no hydrogen 3.415 N/A LEU 249.A N MET 245.A O no hydrogen 3.099 N/A LYS 250.A N GLU 247.A O no hydrogen 3.274 N/A LYS 251.A NZ SER 227.A OG no hydrogen 2.723 N/A GLU 255.A N LYS 252.A O no hydrogen 2.896 N/A ARG 256.A N ARG 253.A O no hydrogen 3.181 N/A ARG 256.A NE LYS 250.A O no hydrogen 2.765 N/A ARG 256.A NH1 GLU 175.A OE2 no hydrogen 2.866 N/A ARG 256.A NH1 GLN 188.A O no hydrogen 3.019 N/A ARG 256.A NH2 GLU 175.A OE1 no hydrogen 2.894 N/A ARG 256.A NH2 LYS 250.A O no hydrogen 2.990 N/A ILE 262.A N SER 258.A O no hydrogen 3.006 N/A LEU 263.A N PHE 259.A O no hydrogen 2.780 N/A ALA 264.A N PRO 260.A O no hydrogen 3.070 N/A GLU 265.A N ARG 261.A O no hydrogen 3.064 N/A ILE 266.A N ILE 262.A O no hydrogen 3.018 N/A GLU 267.A N LEU 263.A O no hydrogen 2.825 N/A GLU 268.A N ALA 264.A O no hydrogen 3.046 N/A LEU 269.A N GLU 265.A O no hydrogen 3.038 N/A ALA 270.A N ILE 266.A O no hydrogen 2.846 N/A ARG 271.A N GLU 267.A O no hydrogen 3.040 N/A GLU 272.A N GLU 268.A O no hydrogen 3.066 N/A LEU 273.A N LEU 269.A O no hydrogen 2.979 N/A SER 274.A N ARG 271.A O no hydrogen 3.140 N/A SER 274.A OG ARG 271.A O no hydrogen 2.827 N/A