Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ca3_P.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N GLN 27.A O no hydrogen 2.911 N/A THR 5.A N VAL 73.A O no hydrogen 2.908 N/A THR 5.A OG1 ALA 67.A O no hydrogen 3.222 N/A THR 5.A OG1 SER 71.A OG no hydrogen 2.261 N/A VAL 6.A N ILE 29.A O no hydrogen 2.969 N/A PHE 7.A N ILE 75.A O no hydrogen 2.918 N/A GLY 11.A N ALA 9.A O no hydrogen 2.729 N/A TYR 16.A OH GLU 158.A OE1 no hydrogen 3.232 N/A VAL 17.A N LEU 13.A O no hydrogen 2.973 N/A VAL 18.A N GLY 14.A O no hydrogen 2.885 N/A ASN 19.A N ARG 15.A O no hydrogen 2.881 N/A HIS 20.A N TYR 16.A O no hydrogen 2.945 N/A HIS 20.A ND1 TYR 16.A O no hydrogen 3.056 N/A LEU 21.A N VAL 17.A O no hydrogen 2.940 N/A GLY 22.A N VAL 18.A O no hydrogen 2.889 N/A ARG 23.A N ASN 19.A O no hydrogen 2.933 N/A ARG 23.A NE ASN 19.A OD1 no hydrogen 3.574 N/A MET 24.A N HIS 20.A O no hydrogen 2.894 N/A GLY 25.A N LEU 21.A O no hydrogen 2.938 N/A GLY 25.A N GLY 22.A O no hydrogen 2.983 N/A SER 26.A N LEU 21.A O no hydrogen 3.303 N/A SER 26.A OG LEU 21.A O no hydrogen 3.251 N/A GLN 27.A N VAL 2.A O no hydrogen 2.935 N/A VAL 28.A N GLN 50.A O no hydrogen 2.920 N/A ILE 29.A N ALA 4.A O no hydrogen 2.867 N/A ILE 30.A N THR 52.A O no hydrogen 2.880 N/A TYR 32.A N LEU 54.A O no hydrogen 2.909 N/A CYS 34.A SG ASP 35.A O no hydrogen 3.458 N/A ASP 38.A N ASP 35.A O no hydrogen 2.985 N/A ILE 39.A N VAL 36.A O no hydrogen 3.320 N/A ARG 43.A N ILE 39.A O no hydrogen 2.964 N/A ARG 43.A N MET 40.A O no hydrogen 2.941 N/A MET 45.A N LEU 42.A O no hydrogen 2.988 N/A GLN 50.A N ASP 47.A O no hydrogen 3.265 N/A THR 52.A N VAL 28.A O no hydrogen 2.897 N/A LEU 54.A N ILE 30.A O no hydrogen 2.963 N/A TRP 56.A N TYR 32.A O no hydrogen 2.908 N/A ASP 57.A N SER 63.A OG no hydrogen 3.388 N/A ARG 59.A N ASP 57.A OD1 no hydrogen 2.894 N/A ASP 62.A N ASP 60.A OD1 no hydrogen 2.785 N/A SER 63.A OG ASP 57.A O no hydrogen 3.017 N/A SER 63.A OG ASP 60.A O no hydrogen 2.376 N/A ARG 65.A N LYS 61.A O no hydrogen 2.939 N/A ARG 65.A NH2 ASP 62.A OD1 no hydrogen 2.998 N/A LYS 66.A N ASP 62.A O no hydrogen 2.891 N/A ALA 67.A N SER 63.A O no hydrogen 2.893 N/A VAL 68.A N ILE 64.A O no hydrogen 2.967 N/A GLN 69.A N LYS 66.A O no hydrogen 3.401 N/A SER 71.A OG THR 5.A OG1 no hydrogen 2.261 N/A SER 71.A OG ALA 67.A O no hydrogen 3.396 N/A ASN 72.A N VAL 3.A O no hydrogen 2.821 N/A VAL 73.A N VAL 3.A O no hydrogen 2.944 N/A VAL 74.A N ARG 111.A O no hydrogen 2.919 N/A ILE 75.A N THR 5.A O no hydrogen 2.879 N/A ASN 76.A N ILE 113.A O no hydrogen 2.898 N/A ARG 85.A NH2 ASN 86.A OD1 no hydrogen 3.372 N/A ASP 91.A N ASP 88.A OD1 no hydrogen 3.010 N/A VAL 92.A N ASP 88.A O no hydrogen 2.897 N/A PHE 93.A N PHE 89.A O no hydrogen 2.901 N/A ASN 95.A N GLU 90.A O no hydrogen 3.439 N/A ILE 96.A N ASP 91.A O no hydrogen 3.052 N/A ARG 98.A N VAL 94.A O no hydrogen 2.802 N/A ARG 98.A NH1 ASN 95.A OD1 no hydrogen 3.406 N/A ARG 98.A NH1 GLU 138.A OE1 no hydrogen 3.192 N/A ALA 99.A N ASN 95.A O no hydrogen 2.838 N/A ILE 100.A N ILE 96.A O no hydrogen 2.901 N/A ALA 101.A N PRO 97.A O no hydrogen 2.880 N/A GLN 102.A N ARG 98.A O no hydrogen 2.893 N/A ALA 103.A N ALA 99.A O no hydrogen 2.924 N/A SER 104.A N ILE 100.A O no hydrogen 2.892 N/A SER 104.A OG ILE 100.A O no hydrogen 2.359 N/A LYS 105.A N ALA 101.A O no hydrogen 2.878 N/A GLU 106.A N GLN 102.A O no hydrogen 2.913 N/A ALA 107.A N ALA 103.A O no hydrogen 2.904 N/A GLY 108.A N SER 104.A O no hydrogen 2.889 N/A VAL 109.A N SER 104.A O no hydrogen 3.101 N/A ARG 111.A N ASN 72.A O no hydrogen 2.943 N/A ARG 111.A NH1 ASP 203.A O no hydrogen 3.122 N/A ARG 111.A NH2 ASP 203.A O no hydrogen 2.699 N/A ILE 113.A N VAL 74.A O no hydrogen 2.894 N/A HIS 114.A N ILE 147.A O no hydrogen 3.002 N/A SER 116.A N ILE 149.A O no hydrogen 2.664 N/A SER 116.A OG GLU 136.A OE2 no hydrogen 2.582 N/A LEU 118.A N PRO 151.A O no hydrogen 2.791 N/A ASN 119.A N HIS 117.A ND1 no hydrogen 3.299 N/A ASN 119.A ND2 ASP 274.A OD1 no hydrogen 2.586 N/A ALA 120.A N HIS 117.A O no hydrogen 3.164 N/A LYS 123.A N SER 121.A OG no hydrogen 2.987 N/A SER 124.A N SER 121.A O no hydrogen 3.383 N/A SER 124.A OG ASN 119.A O no hydrogen 3.076 N/A SER 124.A OG SER 121.A O no hydrogen 3.562 N/A SER 126.A OG ASP 265.A OD1 no hydrogen 2.383 N/A LYS 127.A NZ GLU 83.A OE1 no hydrogen 3.403 N/A LYS 127.A NZ GLU 83.A OE2 no hydrogen 2.785 N/A SER 128.A N ASP 265.A OD1 no hydrogen 3.062 N/A SER 128.A OG ASP 265.A OD2 no hydrogen 2.354 N/A ARG 130.A N SER 126.A O no hydrogen 2.934 N/A ARG 130.A NE SER 124.A O no hydrogen 2.907 N/A SER 131.A N LYS 127.A O no hydrogen 2.908 N/A SER 131.A OG LYS 127.A O no hydrogen 3.165 N/A LYS 132.A N SER 128.A O no hydrogen 2.864 N/A LYS 132.A NZ SER 116.A O no hydrogen 3.052 N/A ALA 133.A N LEU 129.A O no hydrogen 3.002 N/A VAL 134.A N ARG 130.A O no hydrogen 3.422 N/A GLY 135.A N SER 131.A O no hydrogen 2.884 N/A GLU 136.A N LYS 132.A O no hydrogen 2.878 N/A LYS 137.A N ALA 133.A O no hydrogen 3.004 N/A GLU 138.A N VAL 134.A O no hydrogen 2.896 N/A VAL 139.A N GLY 135.A O no hydrogen 2.879 N/A ARG 140.A N GLU 136.A O no hydrogen 2.936 N/A SER 141.A N LYS 137.A O no hydrogen 2.893 N/A VAL 142.A N GLU 138.A O no hydrogen 2.928 N/A PHE 143.A N VAL 139.A O no hydrogen 2.885 N/A ALA 146.A N PHE 143.A O no hydrogen 2.773 N/A ILE 147.A N PHE 112.A O no hydrogen 2.917 N/A ILE 148.A N LYS 209.A O no hydrogen 3.069 N/A ILE 149.A N HIS 114.A O no hydrogen 2.821 N/A ARG 150.A N PHE 211.A O no hydrogen 2.869 N/A ARG 150.A NH1 GLU 136.A OE1 no hydrogen 3.223 N/A ARG 150.A NH1 GLU 136.A OE2 no hydrogen 3.528 N/A SER 152.A N PHE 213.A O no hydrogen 2.925 N/A SER 152.A OG GLN 186.A O no hydrogen 2.602 N/A SER 152.A OG ASP 274.A OD2 no hydrogen 3.144 N/A ASP 153.A N SER 152.A OG no hydrogen 2.578 N/A PHE 155.A N VAL 188.A O no hydrogen 3.039 N/A GLY 156.A N ASP 159.A OD2 no hydrogen 2.990 N/A ASP 159.A N GLY 156.A O no hydrogen 3.426 N/A LEU 162.A N ASP 159.A OD2 no hydrogen 3.251 N/A ASN 163.A N ASP 159.A OD1 no hydrogen 3.302 N/A ASN 163.A ND2 ARG 157.A O no hydrogen 3.102 N/A PHE 165.A N PHE 161.A O no hydrogen 2.917 N/A ALA 166.A N LEU 162.A O no hydrogen 2.901 N/A ASN 167.A N ASN 163.A O no hydrogen 2.921 N/A TYR 168.A N PHE 165.A O no hydrogen 2.905 N/A TYR 168.A OH HIS 164.A NE2 no hydrogen 3.408 N/A ARG 169.A N ALA 166.A O no hydrogen 3.488 N/A ARG 169.A NH1 ALA 166.A O no hydrogen 2.901 N/A ARG 169.A NH1 HIS 304.A ND1 no hydrogen 3.095 N/A TRP 170.A N ASN 167.A O no hydrogen 3.285 N/A PHE 171.A N TYR 168.A O no hydrogen 2.987 N/A LEU 172.A N ARG 169.A O no hydrogen 3.017 N/A ALA 173.A N PHE 171.A O no hydrogen 2.464 N/A VAL 174.A N ILE 237.A O no hydrogen 2.879 N/A LEU 176.A N TYR 239.A O no hydrogen 2.942 N/A GLY 180.A N VAL 177.A O no hydrogen 3.170 N/A THR 183.A OG1 LYS 182.A O no hydrogen 2.436 N/A THR 183.A OG1 HIS 271.A O no hydrogen 3.284 N/A LYS 185.A N TYR 219.A O no hydrogen 2.722 N/A LYS 185.A NZ ASP 153.A OD2 no hydrogen 3.101 N/A LYS 185.A NZ ARG 269.A O no hydrogen 2.964 N/A LYS 185.A NZ ILE 272.A O no hydrogen 3.357 N/A GLN 186.A N ASP 274.A OD2 no hydrogen 2.741 N/A GLN 186.A NE2 GLY 215.A O no hydrogen 2.530 N/A VAL 188.A N ASP 153.A O no hydrogen 2.598 N/A TYR 189.A OH GLU 299.A OE2 no hydrogen 2.695 N/A VAL 190.A N PHE 155.A O no hydrogen 3.401 N/A VAL 193.A N TYR 189.A O no hydrogen 2.949 N/A SER 194.A N VAL 190.A O no hydrogen 2.905 N/A SER 194.A OG HIS 20.A ND1 no hydrogen 3.241 N/A LYS 195.A N ALA 191.A O no hydrogen 2.891 N/A GLY 196.A N ASP 192.A O no hydrogen 2.880 N/A ILE 197.A N VAL 193.A O no hydrogen 2.936 N/A VAL 198.A N SER 194.A O no hydrogen 2.945 N/A ASN 199.A N LYS 195.A O no hydrogen 2.874 N/A ASN 199.A ND2 LEU 286.A O no hydrogen 3.472 N/A ALA 200.A N GLY 196.A O no hydrogen 2.878 N/A THR 201.A N ILE 197.A O no hydrogen 2.984 N/A THR 201.A N VAL 198.A O no hydrogen 3.001 N/A THR 201.A OG1 VAL 198.A O no hydrogen 1.927 N/A LYS 202.A N ASN 199.A O no hydrogen 2.965 N/A ASP 203.A N ASN 199.A O no hydrogen 2.889 N/A ALA 206.A N ASP 203.A O no hydrogen 3.223 N/A LYS 209.A N ALA 206.A O no hydrogen 3.237 N/A LYS 209.A NZ ASP 205.A O no hydrogen 3.195 N/A PHE 211.A N ILE 148.A O no hydrogen 2.740 N/A PHE 213.A N ARG 150.A O no hydrogen 3.296 N/A ASN 217.A ND2 TYR 219.A OH no hydrogen 3.288 N/A ARG 218.A NH1 GLN 186.A OE1 no hydrogen 2.869 N/A ARG 218.A NH1 VAL 275.A O no hydrogen 2.537 N/A ARG 218.A NH2 ASP 274.A O no hydrogen 2.808 N/A TYR 219.A N LYS 185.A O no hydrogen 2.844 N/A TYR 219.A OH GLU 294.A OE1 no hydrogen 3.211 N/A TYR 219.A OH GLU 294.A OE2 no hydrogen 2.961 N/A LEU 221.A N THR 183.A O no hydrogen 2.830 N/A LEU 224.A N LEU 220.A O no hydrogen 2.890 N/A VAL 225.A N LEU 221.A O no hydrogen 2.921 N/A LYS 226.A N PHE 222.A O no hydrogen 2.886 N/A TYR 227.A N HIS 223.A O no hydrogen 2.882 N/A TYR 227.A OH SER 297.A OG no hydrogen 2.703 N/A ILE 228.A N LEU 224.A O no hydrogen 2.910 N/A PHE 229.A N VAL 225.A O no hydrogen 2.932 N/A GLY 230.A N LYS 226.A O no hydrogen 2.874 N/A MET 231.A N TYR 227.A O no hydrogen 2.896 N/A THR 232.A N ILE 228.A O no hydrogen 2.948 N/A THR 232.A OG1 ILE 228.A O no hydrogen 3.242 N/A THR 232.A OG1 THR 232.A O no hydrogen 2.446 N/A ARG 234.A N PHE 229.A O no hydrogen 3.087 N/A ARG 234.A NE HIS 304.A O no hydrogen 3.276 N/A ARG 234.A NH2 HIS 304.A O no hydrogen 2.993 N/A TYR 239.A N VAL 174.A O no hydrogen 2.935 N/A LEU 241.A N LEU 176.A O no hydrogen 2.873 N/A TYR 246.A N PRO 242.A O no hydrogen 2.963 N/A TYR 246.A OH PRO 175.A O no hydrogen 2.372 N/A SER 247.A N LEU 243.A O no hydrogen 2.821 N/A TRP 248.A N PHE 244.A O no hydrogen 2.937 N/A ILE 249.A N VAL 245.A O no hydrogen 2.938 N/A GLY 250.A N TYR 246.A O no hydrogen 2.922 N/A LYS 251.A N SER 247.A O no hydrogen 2.844 N/A LEU 252.A N TRP 248.A O no hydrogen 2.934 N/A PHE 253.A N ILE 249.A O no hydrogen 2.952 N/A GLY 254.A N GLY 250.A O no hydrogen 2.878 N/A GLY 254.A N LYS 251.A O no hydrogen 3.216 N/A LEU 255.A N LEU 252.A O no hydrogen 3.258 N/A SER 256.A OG PHE 253.A O no hydrogen 3.488 N/A LYS 266.A NZ ARG 160.A O no hydrogen 3.388 N/A VAL 267.A N THR 263.A O no hydrogen 2.919 N/A GLU 268.A N LYS 264.A O no hydrogen 2.931 N/A ARG 269.A N ASP 265.A O no hydrogen 2.897 N/A ILE 270.A N LYS 266.A O no hydrogen 2.880 N/A HIS 271.A N VAL 267.A O no hydrogen 2.964 N/A HIS 271.A N GLU 268.A O no hydrogen 3.256 N/A ILE 272.A N GLU 268.A O no hydrogen 2.919 N/A ASP 274.A N VAL 184.A O no hydrogen 2.719 N/A VAL 275.A N ASN 119.A OD1 no hydrogen 3.176 N/A THR 278.A OG1 MET 276.A O no hydrogen 3.015 N/A THR 278.A OG1 PRO 277.A O no hydrogen 2.265 N/A GLU 284.A N GLU 284.A OE1 no hydrogen 2.567 N/A ASP 285.A N GLY 282.A O no hydrogen 3.161 N/A GLY 287.A N LEU 283.A O no hydrogen 2.926 N/A GLY 287.A N GLU 284.A O no hydrogen 3.291 N/A VAL 288.A N LEU 283.A O no hydrogen 3.226 N/A THR 291.A N ASP 192.A OD2 no hydrogen 2.599 N/A THR 291.A OG1 ASP 192.A OD2 no hydrogen 2.801 N/A GLU 294.A N GLU 294.A OE1 no hydrogen 2.447 N/A SER 297.A OG TYR 227.A OH no hydrogen 2.703 N/A SER 297.A OG LEU 293.A O no hydrogen 2.899 N/A SER 297.A OG GLU 294.A O no hydrogen 3.211 N/A VAL 300.A N SER 297.A O no hydrogen 3.182 N/A LEU 301.A N SER 297.A O no hydrogen 2.913 N/A LEU 301.A N ILE 298.A O no hydrogen 3.186 N/A ARG 302.A N ILE 298.A O no hydrogen 2.907 N/A ARG 302.A NH1 LEU 310.A O no hydrogen 2.941 N/A HIS 304.A N LEU 301.A O no hydrogen 3.255 N/A ARG 305.A NE MET 231.A O no hydrogen 2.755 N/A ARG 305.A NH1 LEU 310.A O no hydrogen 3.277 N/A ARG 305.A NH1 SER 312.A O no hydrogen 3.307 N/A ARG 305.A NH2 MET 231.A O no hydrogen 2.872 N/A ARG 308.A NH1 ARG 308.A O no hydrogen 3.093 N/A TRP 309.A N THR 306.A O no hydrogen 2.969 N/A LEU 310.A N TYR 307.A O no hydrogen 3.203 N/A GLU 316.A N GLU 313.A O no hydrogen 2.924 N/A VAL 323.A N ARG 218.A O no hydrogen 2.869 N/A